nitrous oxide has been researched along with Neuropathy, Subacute Combined Degeneration in 36 studies
Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nitrous oxide abuse is a rare cause of vitamin B12 deficiency and consequent subacute combined degeneration of the spinal cord." | 5.56 | Pernicious azotaemia? A case series of subacute combined degeneration of the cord secondary to nitrous oxide abuse. ( Gaillard, F; McArdle, DJT, 2020) |
| "Nitrous oxide (N2O), a long-standing anesthetic, is also neurotoxic by interfering with the bioavailability of vitamin B12 if abused." | 5.46 | Nitrous oxide induced subacute combined degeneration with longitudinally extensive myelopathy with inverted V-sign on spinal MRI: a case report and literature review. ( Hu, WL; Jiang, T; Wang, SK; Yuan, JL, 2017) |
| "She exhibited dystonia in four limbs with athetoid movement in fingers and toes, worsened by eye closure." | 5.43 | Nitrous Oxide-induced Subacute Combined Degeneration Presenting with Dystonia and Pseudoathetosis: A Case Report. ( Chen, HJ; Huang, CS, 2016) |
| "In patients with postsurgical myelopathy, surgeons should evaluate B12 status and consider the possibility that nitrous oxide could cause a subclinical B12 deficiency to become overt, particularly in patients with malabsorptive GI comorbidities." | 4.98 | Subacute combined degeneration of the spinal cord following nitrous oxide anesthesia: A systematic review of cases. ( Alshafai, N; Cheng, J; Gimbel, D; Gunness, VRN; Hersey, D; Mejia Munne, JC; Nasser, R; Nouri, A; Patel, KK; Sciubba, D, 2018) |
| "We report four cases of subacute combined degeneration induced by recreational nitrous oxide abuse despite self-administered vitamin B12 supplementation." | 1.72 | Nitrous oxide abuse induced subacute combined degeneration despite patient initiated B12 supplementation. ( Horowitz, BZ; Temple, C, 2022) |
| "Several studies have reported subacute combined degeneration (SCD) induced by nitrous oxide (N2O) abuse." | 1.72 | An unusual case of subacute combined degeneration due to nitrous oxide abuse, which relapsed after bariatric surgery: A case report. ( Bi, Y; Chen, W; Si, Z; Yang, B, 2022) |
| "Clinicians diagnose subacute combined degeneration of the spinal cord, especially when the patient has no gastrointestinal disease, diet, malnutrition, etc." | 1.62 | [A case of subacute combined degeneration of spinal cord caused by inhaling laughing gas]. ( Liu, Y; Lu, ZM; Ni, MY; Pan, XJ; Wang, ZY; Zhang, ZN, 2021) |
| "Nitrous oxide abuse is a rare cause of vitamin B12 deficiency and consequent subacute combined degeneration of the spinal cord." | 1.56 | Pernicious azotaemia? A case series of subacute combined degeneration of the cord secondary to nitrous oxide abuse. ( Gaillard, F; McArdle, DJT, 2020) |
| "Nitrous oxide (N2O), a long-standing anesthetic, is also neurotoxic by interfering with the bioavailability of vitamin B12 if abused." | 1.46 | Nitrous oxide induced subacute combined degeneration with longitudinally extensive myelopathy with inverted V-sign on spinal MRI: a case report and literature review. ( Hu, WL; Jiang, T; Wang, SK; Yuan, JL, 2017) |
| "She exhibited dystonia in four limbs with athetoid movement in fingers and toes, worsened by eye closure." | 1.43 | Nitrous Oxide-induced Subacute Combined Degeneration Presenting with Dystonia and Pseudoathetosis: A Case Report. ( Chen, HJ; Huang, CS, 2016) |
| "A case of subacute combined degeneration (SCD) of the spinal cord manifesting as severe ataxia and urinary retention in a patient with a history of heavy nitrous oxide abuse and self-supplementation with cyanocobalamin is reported." | 1.42 | Subacute combined degeneration of the spinal cord in a patient abusing nitrous oxide and self-medicating with cyanocobalamin. ( Ambrose, TM; Neuburger, KJ; Oettinger, GR; Pugliese, RS; Slagle, EJ, 2015) |
| "This case discusses subacute combined degeneration of the spinal cord on a background of N2O abuse." | 1.39 | Subacute combined degeneration of the spinal cord following recreational nitrous oxide use. ( Cheng, HM; Hernstadt, D; Park, JH, 2013) |
| "Copper deficiency myelopathy (CDM) is an increasingly recognised mimic of subacute combined degeneration (SCD) of the cord due to cobalamin (vitamin B(12)) deficiency." | 1.35 | Copper deficiency myelopathy and subacute combined degeneration of the cord - why is the phenotype so similar? ( Jaiser, SR; Winston, GP, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (11.11) | 29.6817 |
| 2010's | 12 (33.33) | 24.3611 |
| 2020's | 20 (55.56) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 1 |
| Dong, J | 1 |
| Xu, R | 1 |
| Feng, F | 1 |
| Kan, W | 1 |
| Ding, H | 1 |
| Wang, X | 2 |
| Chen, Y | 1 |
| Zhu, S | 1 |
| Dong, R | 1 |
| Cao, J | 1 |
| Ran, L | 1 |
| Liu, C | 1 |
| Li, Z | 2 |
| Liu, Y | 1 |
| Wang, ZY | 1 |
| Zhang, ZN | 1 |
| Ni, MY | 1 |
| Lu, ZM | 1 |
| Pan, XJ | 1 |
| Wong, J | 1 |
| Viyasar, T | 1 |
| Layton, B | 1 |
| Lauder, J | 1 |
| Temple, C | 2 |
| Horowitz, BZ | 2 |
| Yoon, JY | 1 |
| Klein, JP | 1 |
| Chen, W | 1 |
| Si, Z | 1 |
| Bi, Y | 1 |
| Yang, B | 1 |
| Paris, A | 1 |
| Lake, L | 1 |
| Joseph, A | 1 |
| Workman, A | 1 |
| Walton, J | 1 |
| Hayton, T | 1 |
| Evangelou, N | 1 |
| Lilleker, JB | 1 |
| Ayling, RM | 1 |
| Nicholl, D | 1 |
| Noyce, AJ | 1 |
| Vitte, T | 1 |
| Castrioto, A | 1 |
| Schmitt, E | 1 |
| Moro, E | 1 |
| Potel, SR | 1 |
| Al Omari, O | 1 |
| Ahmed, A | 1 |
| Patel, D | 1 |
| Jani, C | 1 |
| Singh, H | 1 |
| Sasson, P | 1 |
| AbdelRazek, M | 1 |
| Gardin, TM | 1 |
| Yang, A | 1 |
| Moeller, JJ | 1 |
| Quraishi, IH | 1 |
| Mogensen, MA | 1 |
| Fink, JR | 1 |
| McArdle, DJT | 1 |
| Gaillard, F | 1 |
| Jiang, J | 1 |
| Shang, X | 1 |
| Zhao, B | 1 |
| Zhao, L | 1 |
| Zhao, R | 1 |
| Seed, A | 1 |
| Jogia, M | 1 |
| Zhang, S | 1 |
| Zhou, Z | 1 |
| Wu, W | 1 |
| Yu, Q | 1 |
| Hong, M | 1 |
| Lai, Y | 1 |
| Cheng, J | 2 |
| Yang, Z | 1 |
| Padayachee, Y | 1 |
| Richards, C | 1 |
| Morgan, O | 1 |
| Yuan, JL | 1 |
| Wang, SK | 1 |
| Jiang, T | 1 |
| Hu, WL | 1 |
| Antonucci, MU | 1 |
| Anderson, D | 1 |
| Beecher, G | 1 |
| van Dijk, R | 1 |
| Hussain, M | 1 |
| Siddiqi, Z | 1 |
| Ba, F | 1 |
| Jolobe, OMP | 1 |
| Patel, KK | 1 |
| Mejia Munne, JC | 1 |
| Gunness, VRN | 1 |
| Hersey, D | 1 |
| Alshafai, N | 1 |
| Sciubba, D | 1 |
| Nasser, R | 1 |
| Gimbel, D | 1 |
| Nouri, A | 1 |
| Lan, SY | 1 |
| Kuo, CY | 1 |
| Chou, CC | 1 |
| Kong, SS | 1 |
| Hung, PC | 1 |
| Tsai, HY | 1 |
| Chen, YC | 1 |
| Lin, JJ | 1 |
| Chou, IJ | 1 |
| Lin, KL | 1 |
| Cheng, HM | 1 |
| Park, JH | 1 |
| Hernstadt, D | 1 |
| Chin, J | 1 |
| Forzani, B | 1 |
| Chowdhury, N | 1 |
| Lombardo, S | 1 |
| Rizzo, JR | 1 |
| Ragucci, M | 1 |
| Pugliese, RS | 1 |
| Slagle, EJ | 1 |
| Oettinger, GR | 1 |
| Neuburger, KJ | 1 |
| Ambrose, TM | 1 |
| Chen, HJ | 1 |
| Huang, CS | 1 |
| Renard, D | 1 |
| Dutray, A | 1 |
| Remy, A | 1 |
| Castelnovo, G | 1 |
| Labauge, P | 1 |
| Hathout, L | 1 |
| El-Saden, S | 1 |
| Lin, RJ | 1 |
| Chen, HF | 1 |
| Chang, YC | 1 |
| Su, JJ | 1 |
| Shulman, RM | 1 |
| Geraghty, TJ | 1 |
| Tadros, M | 1 |
| Wu, MS | 1 |
| Hsu, YD | 1 |
| Lin, JC | 1 |
| Chen, SC | 1 |
| Lee, JT | 1 |
| Winston, GP | 1 |
| Jaiser, SR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Longitudinal Assessment of Neurological Recovery in Patients Following Nitrous Oxide Abuse[NCT05714917] | 100 participants (Anticipated) | Observational | 2023-04-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for nitrous oxide and Neuropathy, Subacute Combined Degeneration
| Article | Year |
|---|---|
Subacute combined degeneration of the spinal cord following nitrous oxide anesthesia: A systematic review of cases.
Topics: Adult; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nitrous Oxide; Spinal Cord; Sp | 2018 |
Recreational nitrous oxide abuse related subacute combined degeneration of the spinal cord in adolescents - A case series and literature review.
Topics: Adolescent; Adult; Female; Humans; Male; Nitrous Oxide; Outcome Assessment, Health Care; Subacute Co | 2019 |
Nitrous oxide-induced B₁₂ deficiency myelopathy: Perspectives on the clinical biochemistry of vitamin B₁₂.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cobamides; Cytokines; Folic Acid | 2011 |
Subacute combined degeneration caused by nitrous oxide intoxication: case reports.
Topics: Adolescent; Female; Humans; Magnetic Resonance Imaging; Male; Nitrous Oxide; Spinal Cord Diseases; S | 2011 |
32 other studies available for nitrous oxide and Neuropathy, Subacute Combined Degeneration
| Article | Year |
|---|---|
Clinical epidemiological characteristics of nitrous oxide abusers: A single-center experience in a hospital in China.
Topics: Adolescent; Adult; China; Female; Hospitals; Humans; Male; Nitrous Oxide; Subacute Combined Degenera | 2021 |
Serum copper decrease and cerebellar atrophy in patients with nitrous oxide-induced subacute combined degeneration: two cases report.
Topics: Atrophy; Copper; Humans; Magnetic Resonance Imaging; Nitrous Oxide; Subacute Combined Degeneration | 2021 |
[A case of subacute combined degeneration of spinal cord caused by inhaling laughing gas].
Topics: Cervical Vertebrae; Humans; Magnetic Resonance Imaging; Nitrous Oxide; Spinal Cord; Subacute Combine | 2021 |
The dangers of recreational inhalation of nitrous oxide.
Topics: Adolescent; Humans; Nitrous Oxide; Spinal Cord Diseases; Subacute Combined Degeneration; Vitamin B 1 | 2021 |
Nitrous Oxide "Whippet" Induced Subacute Combined Degeneration of the Spinal Cord.
Topics: Humans; Magnetic Resonance Imaging; Nitrous Oxide; Spinal Cord; Spinal Cord Diseases; Subacute Combi | 2022 |
Nitrous oxide abuse induced subacute combined degeneration despite patient initiated B12 supplementation.
Topics: Dietary Supplements; Humans; Illicit Drugs; Nitrous Oxide; Subacute Combined Degeneration; Substance | 2022 |
Subacute Combined Degeneration from Nitrous Oxide Use.
Topics: Anesthetics, Inhalation; Humans; Magnetic Resonance Imaging; Nitrous Oxide; Spinal Cord Diseases; Su | 2022 |
An unusual case of subacute combined degeneration due to nitrous oxide abuse, which relapsed after bariatric surgery: A case report.
Topics: Adolescent; Bariatric Surgery; Female; Gait Disorders, Neurologic; Homocysteine; Humans; Nitrous Oxi | 2022 |
Nitrous oxide-induced subacute combined degeneration of the cord: diagnosis and treatment.
Topics: Adolescent; Humans; Magnetic Resonance Imaging; Nitrous Oxide; Subacute Combined Degeneration; Vitam | 2023 |
Subacute cognitive impairment in B12 vitamin-deficiency neuromyelopathy secondary to nitrous oxide abuse.
Topics: Cognitive Dysfunction; Humans; Nitrous Oxide; Subacute Combined Degeneration; Vitamin B 12; Vitamin | 2023 |
Subacute Combined Degeneration Caused by Nitrous Oxide Abuse Mimicking Guillain-Barré Syndrome.
Topics: Guillain-Barre Syndrome; Humans; Nitrous Oxide; Subacute Combined Degeneration | 2023 |
Subacute combined degeneration of the spinal cord in a patient with nitrous oxide use and autoimmune atrophic gastritis.
Topics: Adolescent; Atrophy; Gastritis; Gastritis, Atrophic; Humans; Male; Nitrous Oxide; Spinal Cord; Subac | 2023 |
Subacute Combined Degeneration from Nitrous Oxide Abuse.
Topics: Humans; Magnetic Resonance Imaging; Nitrous Oxide; Subacute Combined Degeneration | 2020 |
Pernicious azotaemia? A case series of subacute combined degeneration of the cord secondary to nitrous oxide abuse.
Topics: Adolescent; Azotemia; Female; Humans; Inhalant Abuse; Magnetic Resonance Imaging; Nitrous Oxide; Pyr | 2020 |
Clinical-radiological dissociation in a patient with nitrous oxide-induced subacute combined degeneration: a case report.
Topics: Humans; Magnetic Resonance Imaging; Male; Neuroimaging; Nitrous Oxide; Subacute Combined Degeneratio | 2020 |
Subacute combined degeneration induced by nitrous oxide inhalation: Two case reports.
Topics: Adolescent; Female; Humans; Male; Nitrous Oxide; Subacute Combined Degeneration; Thiamine; Vitamin B | 2020 |
Lessons of the month: Nitrous oxide-induced functional vitamin B
Topics: Adult; Humans; Magnetic Resonance Imaging; Male; Nitrous Oxide; Subacute Combined Degeneration; Vita | 2020 |
Methylprednisolone combined vitamin supplementation reversed rapidly subacute combined degeneration of the spinal cord induced by the abuse of nitrous oxide.
Topics: Dietary Supplements; Humans; Methylprednisolone; Nitrous Oxide; Spinal Cord; Spinal Cord Diseases; S | 2022 |
Appearance of hypersegmented neutrophils in the peripheral blood associated with subacute combined degeneration of the spinal cord due to nitrous oxide abuse.
Topics: Adult; Anesthetics, Inhalation; Humans; Male; Neutrophils; Nitrous Oxide; Spinal Cord; Subacute Comb | 2021 |
Inhaled nitrous oxide-induced functional B
Topics: Humans; Magnetic Resonance Imaging; Male; Nitrous Oxide; Oxides; Spinal Cord Diseases; Subacute Comb | 2021 |
Nitrous oxide induced subacute combined degeneration with longitudinally extensive myelopathy with inverted V-sign on spinal MRI: a case report and literature review.
Topics: Adult; Female; Humans; Magnetic Resonance Imaging; Nitrous Oxide; Spinal Cord Diseases; Subacute Com | 2017 |
Subacute Combined Degeneration from Recreational Nitrous Oxide Inhalation.
Topics: Administration, Inhalation; Adult; Anesthetics; Humans; Magnetic Resonance Imaging; Male; Nitrous Ox | 2018 |
Subacute Combined Degeneration from Nitrous Oxide Abuse in a Patient with Pernicious Anemia.
Topics: Adult; Anemia, Pernicious; Female; Humans; Magnetic Resonance Imaging; Nitrous Oxide; Spinal Cord; S | 2018 |
Other aspects of nitrous oxide-related neuromyelopathy.
Topics: Homocysteine; Humans; Magnetic Resonance Imaging; Nitrous Oxide; Spinal Cord; Subacute Combined Dege | 2019 |
Subacute combined degeneration of the spinal cord following recreational nitrous oxide use.
Topics: Female; Humans; Magnetic Resonance Imaging; Nitrous Oxide; Physical Therapy Modalities; Spinal Cord; | 2013 |
Rehabilitation essential in the recovery of multifactorial subacute combined degeneration.
Topics: Adult; Alcoholism; Anemia, Pernicious; Humans; Male; Nitrous Oxide; Subacute Combined Degeneration; | 2015 |
Subacute combined degeneration of the spinal cord in a patient abusing nitrous oxide and self-medicating with cyanocobalamin.
Topics: Adult; Female; Humans; Magnetic Resonance Imaging; Nitrous Oxide; Self Medication; Spinal Cord Disea | 2015 |
Nitrous Oxide-induced Subacute Combined Degeneration Presenting with Dystonia and Pseudoathetosis: A Case Report.
Topics: Adult; Athetosis; Dystonia; Female; Gait Disorders, Neurologic; Humans; Nitrous Oxide; Subacute Comb | 2016 |
Subacute combined degeneration of the spinal cord caused by nitrous oxide anaesthesia.
Topics: Afferent Pathways; Anesthetics, Inhalation; Causality; Disease Progression; Gait Ataxia; Humans; Iat | 2009 |
A case of unusual substance abuse causing myeloneuropathy.
Topics: Adult; Female; Humans; Magnetic Resonance Imaging; Nitrous Oxide; Subacute Combined Degeneration; Su | 2007 |
Spinal myoclonus in subacute combined degeneration caused by nitrous oxide intoxication.
Topics: Adult; Female; Humans; Magnetic Resonance Imaging; Myoclonus; Nitrous Oxide; Spinal Cord Diseases; S | 2007 |
Copper deficiency myelopathy and subacute combined degeneration of the cord - why is the phenotype so similar?
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Copper; Electron Transport Complex IV; Hu | 2008 |