Page last updated: 2024-10-19

nitrous oxide and Nervous System Disorders

nitrous oxide has been researched along with Nervous System Disorders in 58 studies

Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.

Research Excerpts

ExcerptRelevanceReference
"02 mg X kg-1) on succinylcholine-induced fasciculations and myoglobinaemia was studied in 64 healthy children (ages two to nine years), anaesthetized with halothane, nitrous oxide and oxygen."7.67Succinylcholine, fasciculations and myoglobinaemia. ( Blanc, VF; Brisson, G; Vaillancourt, G, 1986)
"N2O inactivates vitamin B12, leading to vitamin B12 deficiency and subsequent to hyperhomocysteinemia, which is associated with the formation of fibrinolysis-resistant blood thrombi."5.62[Thromboembolisms due to recreational use of nitrous oxide]. ( de Metz, J; Fokkema, TMM; Kuipers, RS; Oomens, T; Riezebos, RK; van den Bogaard, B; van Nieuwenhuizen, RC, 2021)
"A 50% nitrous oxide/oxygen (N(2)O/O(2)) premix is widely used to alleviate pain or anxiety during brief care procedures in various medical domains."5.12Safety of inhalation of a 50% nitrous oxide/oxygen premix: a prospective survey of 35 828 administrations. ( Gil, P; Hennequin, M; Onody, P, 2006)
"02 mg X kg-1) on succinylcholine-induced fasciculations and myoglobinaemia was studied in 64 healthy children (ages two to nine years), anaesthetized with halothane, nitrous oxide and oxygen."3.67Succinylcholine, fasciculations and myoglobinaemia. ( Blanc, VF; Brisson, G; Vaillancourt, G, 1986)
"Nitrous oxide anaesthesia is a particular risk."2.47Vitamin B12 deficiency and phenylketonuria. ( Walter, JH, 2011)
"Nitrous oxide has been used as a component of general anesthesia for over 160 years and has contributed to countless apparently uneventful anesthetics in neurologically at-risk patients."2.46Is nitrous oxide use appropriate in neurosurgical and neurologically at-risk patients? ( Lanier, WL; Pasternak, JJ, 2010)
"A vitamin B12 deficiency is unusual in pregnant women who consume a normal, varied diet."2.37Clinical chemistry of vitamin B12. ( Davis, RE, 1985)
"All cases of neurological disorders related to nitrous oxide recreational use reported to the Hauts-de-France addictovigilance center between January 2019 and August 2020 were selected."1.72Myeloneuropathy induced by recreational nitrous oxide use with variable exposure levels. ( Bordet, R; Caous, AS; Carton, L; Deheul, S; Gautier, S; Karam, A; Kuchcinski, G; Largeau, B; Potey, C; Tard, C, 2022)
"N2O inactivates vitamin B12, leading to vitamin B12 deficiency and subsequent to hyperhomocysteinemia, which is associated with the formation of fibrinolysis-resistant blood thrombi."1.62[Thromboembolisms due to recreational use of nitrous oxide]. ( de Metz, J; Fokkema, TMM; Kuipers, RS; Oomens, T; Riezebos, RK; van den Bogaard, B; van Nieuwenhuizen, RC, 2021)
"Nitrous oxide continues to be a valuable agent for the control of pain and anxiety."1.30Nitrous oxide in the dental office. ADA Council on Scientific Affairs; ADA Council on Dental Practice. ( , 1997)

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-199024 (41.38)18.7374
1990's13 (22.41)18.2507
2000's6 (10.34)29.6817
2010's7 (12.07)24.3611
2020's8 (13.79)2.80

Authors

AuthorsStudies
Redmond, J1
Cruse, B1
Kiers, L1
Largeau, B1
Karam, A1
Potey, C1
Caous, AS1
Tard, C1
Carton, L1
Kuchcinski, G1
Gautier, S1
Deheul, S1
Bordet, R1
Fang, X1
Li, W1
Gao, H1
Ma, Y1
Dong, X1
Zheng, D1
Bethmont, A1
Harper, CE1
Chan, BS1
Dawson, AH1
McAnulty, J1
Brosset, C1
The Nguyen, H1
Do Van, T1
Giang Thuc, A1
Vallès, M1
Soler, D1
Albu, S1
Kumru, H1
Oomens, T1
Fokkema, TMM1
van den Bogaard, B1
de Metz, J1
van Nieuwenhuizen, RC1
Riezebos, RK1
Kuipers, RS1
Dang, XT1
Nguyen, TX1
Nguyen, TTH1
Ha, HT1
Sluyts, Y1
Pals, P1
Amir, R1
Vanherpe, P1
Egan, W1
Steinberg, E1
Rose, J1
de Vasconcellos, K1
Sneyd, JR1
Thompson, AG1
Leite, MI1
Lunn, MP1
Bennett, DL1
Pasternak, JJ3
McGregor, DG2
Lanier, WL3
Schroeder, DR2
Rusy, DA2
Hindman, B2
Clarke, W2
Torner, J2
Todd, MM2
Reynolds, F1
Walter, JH1
Weimann, J1
KIHLMAN, BA1
Onody, P1
Gil, P1
Hennequin, M1
Culley, DJ1
Crosby, G1
Hogan, K1
Samra, S1
Bayman, EO1
Weeks, J1
van der Westhuyzen, J3
Fernandes-Costa, F2
Metz, J4
Kanazawa, S1
Drivas, G1
Herbert, V1
Brodsky, JB1
Cohen, EN1
Brown, BW1
Wu, ML1
Whitcher, CE1
Michenfelder, JD1
Dyck, PJ1
Grina, LA1
Lambert, EH1
Calder, CS1
Oviatt, K1
Rehder, K1
Lund, BA1
Skau, KA1
King, M1
Coulter, C1
Boyle, RS1
Whitby, RM1
McMorrow, AM1
Adams, RJ1
Rubenstein, MN1
Hoffman, WE1
Thomas, C1
Albrecht, RF1
Werner, C1
Möllenberg, O1
Kochs, E1
Lucchini, R1
Placidi, D1
Toffoletto, F1
Alessio, L1
Howard, WR1
Mayall, M1
Iwata, K1
O'Keefe, GB1
Karanas, A1
Layzer, RB1
Eadie, MJ1
Malan, MD1
Crago, RR1
Stacy, CB1
Di Rocco, A1
Gould, RJ1
Chanarin, I1
Deacon, R1
Lumb, M1
Perry, J1
Melon, E1
Homs, JB1
Jastak, JT1
Gillman, MA2
Lichtigfeld, FJ1
Peduto, VA1
Napoleone, M1
Kano, Y1
Sakamoto, S1
Miura, Y1
Takaku, F1
Heyer, EJ1
Simpson, DM1
Bodis-Wollner, I1
Diamond, SP1
Davis, RE2
Icke, GC1
Weir, DG1
Keating, S1
Molloy, A1
McPartlin, J1
Kennedy, S1
Blanchflower, J1
Kennedy, DG1
Rice, D1
Scott, JM1
Blanc, VF1
Vaillancourt, G1
Brisson, G1
Schilling, RF1
Pope, WD1
Halsey, MJ1
Hammond, G1
Ward, CF1
McPherson, RW1
Mahla, M1
Johnson, R1
Traystman, RJ1
Murdoch, BD1
Fleming, JH1
Lines, JG1
Loder, RE1
Millar, RA1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Improving Labour Induction Analgesia: a Randomized Control Trial of Single Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour[NCT04011098]Phase 15 participants (Actual)Interventional2019-07-01Terminated (stopped due to Unable to meet recruitment numbers, lack of participation)
Evaluation of the Effectiveness of Transcutaneous Electrical Nerve Stimulation During Labor. A Triple Blind Randomized Clinical Trial[NCT03137251]63 participants (Actual)Interventional2017-05-01Completed
Efficacy of Inhaled 50% Equimolar Nitrous Oxide/Oxygen Gas Premix (Kalinox®) as Compared to Topically Administered 5% Eutectic Mixture of Lidocaine/Prilocaine (EMLA®) in Chronic Leg Ulcer Debridement[NCT02696460]21 participants (Actual)Interventional2010-04-30Completed
Longitudinal Assessment of Neurological Recovery in Patients Following Nitrous Oxide Abuse[NCT05714917]100 participants (Anticipated)Observational2023-04-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

14 reviews available for nitrous oxide and Nervous System Disorders

ArticleYear
Nitrous oxide: are we still in equipoise? A qualitative review of current controversies.
    British journal of anaesthesia, 2013, Volume: 111, Issue:6

    Topics: Analgesics, Non-Narcotic; Anesthetics, Inhalation; Cardiovascular Diseases; Humans; Intraoperative A

2013
Is nitrous oxide use appropriate in neurosurgical and neurologically at-risk patients?
    Current opinion in anaesthesiology, 2010, Volume: 23, Issue:5

    Topics: Anesthesia, General; Anesthetics, Inhalation; Blood Volume; Cerebrovascular Circulation; Electroence

2010
Labour analgesia and the baby: good news is no news.
    International journal of obstetric anesthesia, 2011, Volume: 20, Issue:1

    Topics: Acid-Base Equilibrium; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Apgar Score; Breast Feedin

2011
Labour analgesia and the baby: good news is no news.
    International journal of obstetric anesthesia, 2011, Volume: 20, Issue:1

    Topics: Acid-Base Equilibrium; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Apgar Score; Breast Feedin

2011
Labour analgesia and the baby: good news is no news.
    International journal of obstetric anesthesia, 2011, Volume: 20, Issue:1

    Topics: Acid-Base Equilibrium; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Apgar Score; Breast Feedin

2011
Labour analgesia and the baby: good news is no news.
    International journal of obstetric anesthesia, 2011, Volume: 20, Issue:1

    Topics: Acid-Base Equilibrium; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Apgar Score; Breast Feedin

2011
Vitamin B12 deficiency and phenylketonuria.
    Molecular genetics and metabolism, 2011, Volume: 104 Suppl

    Topics: Humans; Nervous System Diseases; Nitrous Oxide; Phenylketonurias; Vitamin B 12; Vitamin B 12 Deficie

2011
Toxicity of nitrous oxide.
    Best practice & research. Clinical anaesthesiology, 2003, Volume: 17, Issue:1

    Topics: Animals; Bone Marrow; Folic Acid Deficiency; Humans; Methionine; Nervous System Diseases; Nitrous Ox

2003
Nitrous oxide, vitamin B12 deficiency and the methyl folate trap.
    Nutrition reviews, 1982, Volume: 40, Issue:5

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Megaloblastic; Animals; Humans; L

1982
Nitrous oxide in the dental environment: assessing the risk, reducing the exposure.
    Journal of the American Dental Association (1939), 1997, Volume: 128, Issue:3

    Topics: Air Pollution, Indoor; Anesthesia, Dental; Bone Marrow Diseases; Chemical and Drug Induced Liver Inj

1997
Cobalamin deficiency and the pathogenesis of nervous system disease.
    Annual review of nutrition, 1992, Volume: 12

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Disease Models, Animal; Humans;

1992
Cobalamin and folate: recent developments.
    Journal of clinical pathology, 1992, Volume: 45, Issue:4

    Topics: Anemia, Megaloblastic; Female; Folic Acid; Humans; Methylation; Methylmalonic Acid; Nervous System D

1992
Analgesic nitrous oxide in neuropsychiatry: past, present and future.
    The International journal of neuroscience, 1989, Volume: 49, Issue:1-2

    Topics: Humans; Mental Disorders; Nervous System Diseases; Nitrous Oxide

1989
[Poisoning caused by chronic exposure to volatile anesthetics. Molecular mechanisms and risk anesthetics].
    Minerva anestesiologica, 1989, Volume: 55, Issue:12

    Topics: Air Pollutants, Occupational; Biodegradation, Environmental; Bromides; Chemical and Drug Induced Liv

1989
Disorders of cobalamin metabolism.
    Critical reviews in oncology/hematology, 1985, Volume: 3, Issue:1

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Isomerases; Anemia, Pernicious

1985
Nitrous oxide, an opioid addictive agent. Review of the evidence.
    The American journal of medicine, 1986, Volume: 81, Issue:1

    Topics: Analgesia; Animals; Drug Tolerance; Humans; Locomotion; Nervous System Diseases; Nitrous Oxide; Opio

1986
Clinical chemistry of vitamin B12.
    Advances in clinical chemistry, 1985, Volume: 24

    Topics: Absorption; Adult; Alcoholism; Anemia, Pernicious; Ascorbic Acid; Autoantibodies; Biguanides; Biolog

1985

Trials

2 trials available for nitrous oxide and Nervous System Disorders

ArticleYear
Effect of nitrous oxide use on long-term neurologic and neuropsychological outcome in patients who received temporary proximal artery occlusion during cerebral aneurysm clipping surgery.
    Anesthesiology, 2009, Volume: 110, Issue:3

    Topics: Adult; Balloon Occlusion; Cerebral Arteries; Female; Follow-Up Studies; Humans; Intracranial Aneurys

2009
Safety of inhalation of a 50% nitrous oxide/oxygen premix: a prospective survey of 35 828 administrations.
    Drug safety, 2006, Volume: 29, Issue:7

    Topics: Administration, Inhalation; Analgesics, Non-Narcotic; Anesthetics, Combined; Anesthetics, Inhalation

2006

Other Studies

42 other studies available for nitrous oxide and Nervous System Disorders

ArticleYear
Nitrous oxide-induced neurological disorders: an increasing public health concern.
    Internal medicine journal, 2022, Volume: 52, Issue:5

    Topics: Adolescent; Humans; Nervous System Diseases; Nitrous Oxide; Public Health; Substance-Related Disorde

2022
Myeloneuropathy induced by recreational nitrous oxide use with variable exposure levels.
    European journal of neurology, 2022, Volume: 29, Issue:8

    Topics: Adolescent; Adult; Ataxia; Female; Humans; Male; Nervous System Diseases; Nitrous Oxide; Peripheral

2022
Skin hyperpigmentation: a rare presenting symptom of nitrous oxide abuse.
    Clinical toxicology (Philadelphia, Pa.), 2020, Volume: 58, Issue:6

    Topics: China; Female; Humans; Hyperpigmentation; Illicit Drugs; Male; Nervous System Diseases; Nitrous Oxid

2020
Increasing illicit use of nitrous oxide in presentations to NSW emergency departments.
    The Medical journal of Australia, 2019, Volume: 211, Issue:9

    Topics: Adolescent; Adult; Criminal Behavior; Emergency Service, Hospital; Female; Humans; Inhalant Abuse; M

2019
[Neurological complications of nitrous oxide poisoning].
    La Revue du praticien, 2020, Volume: 70, Issue:10

    Topics: Drug-Related Side Effects and Adverse Reactions; Humans; Nervous System Diseases; Nitrous Oxide; Pos

2020
[Neurological complications of nitrous oxide consumption. A case report].
    Revista de neurologia, 2021, Apr-01, Volume: 72, Issue:7

    Topics: Humans; Male; Nervous System Diseases; Nitrous Oxide; Vitamin B 12 Deficiency; Young Adult

2021
[Thromboembolisms due to recreational use of nitrous oxide].
    Nederlands tijdschrift voor geneeskunde, 2021, 04-26, Volume: 165

    Topics: Female; Humans; Illicit Drugs; Male; Nervous System Diseases; Nitrous Oxide; Peripheral Nervous Syst

2021
Nitrous Oxide-Induced Neuropathy among Recreational Users in Vietnam.
    International journal of environmental research and public health, 2021, 06-09, Volume: 18, Issue:12

    Topics: Adolescent; Adult; Humans; Nervous System Diseases; Nitrous Oxide; Peripheral Nervous System Disease

2021
Recreational use of nitrous oxide may cause collateral neurological damage.
    Acta neurologica Belgica, 2021, Volume: 121, Issue:4

    Topics: Adult; Female; Humans; Inhalation Exposure; Male; Nervous System Diseases; Nitrous Oxide; Recreation

2021
Vitamin B
    The American journal of emergency medicine, 2018, Volume: 36, Issue:9

    Topics: Emergency Service, Hospital; Female; Humans; Inhalant Abuse; Nervous System Diseases; Nitrous Oxide;

2018
Whippits, nitrous oxide and the dangers of legal highs.
    Practical neurology, 2015, Volume: 15, Issue:3

    Topics: Adult; Analgesics, Non-Narcotic; Female; Humans; Male; Nervous System Diseases; Nitrous Oxide; Spina

2015
The effect of oxygen, nitric oxide, and respiratory inhibitors on the production of chromosome aberration by x-rays.
    Experimental cell research, 1958, Volume: 14, Issue:3

    Topics: Chromosome Aberrations; Chromosomes; Humans; Nervous System Diseases; Nitric Oxide; Nitrous Oxide; O

1958
Nitrous oxide in neuroanesthesia: tried and true or toxin?
    Anesthesiology, 2008, Volume: 108, Issue:4

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Humans; Nervous System Diseases; Nitrous Oxide

2008
Effect of nitrous oxide on neurologic and neuropsychological function after intracranial aneurysm surgery.
    Anesthesiology, 2008, Volume: 108, Issue:4

    Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Hypothermia, Induced; Intracranial Aneurysm; Male; M

2008
Cobalamin (vitamin B12) analogs are absent in plasma of fruit bats exposed to nitrous oxide.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1982, Volume: 171, Issue:1

    Topics: Animals; Chiroptera; Nervous System Diseases; Nitrous Oxide; Vitamin B 12

1982
Cobalamin inactivation by nitrous oxide produces severe neurological impairment in fruit bats : protection by methionine and aggravation by folates.
    Life sciences, 1982, Nov-01, Volume: 31, Issue:18

    Topics: Animals; Chiroptera; Diet; Folic Acid; Formyltetrahydrofolates; Methionine; Nervous System Diseases;

1982
Exposure to nitrous oxide and neurologic disease among dental professionals.
    Anesthesia and analgesia, 1981, Volume: 60, Issue:5

    Topics: Adult; Anesthesia, Dental; Anesthesia, Inhalation; Dental Assistants; Dentists; Female; Humans; Male

1981
Exposure to anesthetic gases and health problems in dental workers.
    Anesthesiology, 1980, Volume: 53, Issue:1

    Topics: Abortion, Incomplete; Anesthesia, Inhalation; Dental Staff; Dentists; Female; Gases; Humans; Kidney

1980
Nitrous oxide neurotoxicity studies in man and rat.
    Anesthesiology, 1980, Volume: 53, Issue:3

    Topics: Adult; Animals; Dentists; Electromyography; Humans; Median Nerve; Middle Aged; Nerve Fibers; Nerve F

1980
Neurotoxicity from overuse of nitrous oxide.
    The Medical journal of Australia, 1995, Jul-03, Volume: 163, Issue:1

    Topics: Adolescent; Humans; Male; Nervous System Diseases; Nitrous Oxide; Vitamin B 12 Deficiency

1995
Combined system disease after nitrous oxide anesthesia: a case report.
    Neurology, 1995, Volume: 45, Issue:6

    Topics: Adult; Anesthesia; Female; Humans; Nervous System Diseases; Nitrous Oxide; Vitamin B 12 Deficiency

1995
The effect of halothane and isoflurane on neurologic outcome following incomplete cerebral ischemia in the rat.
    Anesthesia and analgesia, 1993, Volume: 76, Issue:2

    Topics: Anesthesia, Inhalation; Animals; Brain Ischemia; Catecholamines; Fentanyl; Halothane; Isoflurane; Ma

1993
Sevoflurane improves neurological outcome after incomplete cerebral ischaemia in rats.
    British journal of anaesthesia, 1995, Volume: 75, Issue:6

    Topics: Anesthetics; Animals; Blood Glucose; Blood Pressure; Carbon Dioxide; Ethers; Fentanyl; Ischemic Atta

1995
Neurotoxicity in operating room personnel working with gaseous and nongaseous anesthesia.
    International archives of occupational and environmental health, 1996, Volume: 68, Issue:3

    Topics: Adult; Anesthesia; Female; Health Personnel; Humans; Hydrocortisone; Male; Nervous System Diseases;

1996
Nitrous oxide in the dental office. ADA Council on Scientific Affairs; ADA Council on Dental Practice.
    Journal of the American Dental Association (1939), 1997, Volume: 128, Issue:3

    Topics: Air Pollution, Indoor; American Dental Association; Anesthesia, Dental; Dental Offices; Dentistry; E

1997
Vitamin B12 deficiency and nitrous oxide.
    Lancet (London, England), 1999, May-01, Volume: 353, Issue:9163

    Topics: Anesthesia, General; Humans; Nervous System Diseases; Nitrous Oxide; Vitamin B 12 Deficiency

1999
Neurologic problems associated with chronic nitrous oxide abuse in a non-healthcare worker.
    The American journal of the medical sciences, 2001, Volume: 322, Issue:3

    Topics: Humans; Inhalation Exposure; Male; Middle Aged; Nervous System Diseases; Nitrous Oxide; Substance-Re

2001
Myeloneuropathy after prolonged exposure to nitrous oxide.
    Lancet (London, England), 1978, Dec-09, Volume: 2, Issue:8102

    Topics: Adult; Anesthesia, Dental; Arm; Dental Technicians; Dentists; Erectile Dysfunction; Humans; Leg; Mal

1978
Nervous laughter--or, hazards of laughing gas.
    The Medical journal of Australia, 1979, May-19, Volume: 1, Issue:10

    Topics: Humans; Nervous System Diseases; Nitrous Oxide; Occupational Diseases; Substance-Related Disorders

1979
Anaesthetic considerations in idiopathic orthostatic hypotension and the Shy-Drager syndrome.
    Canadian Anaesthetists' Society journal, 1979, Volume: 26, Issue:4

    Topics: Adult; Anesthesia; Diazepam; Fecal Incontinence; Fentanyl; Humans; Hypotension, Orthostatic; Lidocai

1979
Methionine in the treatment of nitrous-oxide-induced neuropathy and myeloneuropathy.
    Journal of neurology, 1992, Volume: 239, Issue:7

    Topics: Adult; Anemia, Macrocytic; Female; Humans; Male; Methionine; Nervous System Diseases; Neuromuscular

1992
[Nitrous oxide in neurosurgery].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1991, Volume: 32, Issue:8-9 Spec N

    Topics: Anesthesia, Inhalation; Animals; Brain; Cerebrovascular Circulation; Humans; Intracranial Pressure;

1991
Nitrous oxide and its abuse.
    Journal of the American Dental Association (1939), 1991, Volume: 122, Issue:2

    Topics: Hematopoiesis; Humans; Nervous System Diseases; Nitrous Oxide; Students, Dental; Students, Medical;

1991
Nitrous oxide: clinical and electrophysiologic investigation of neurologic complications.
    Neurology, 1986, Volume: 36, Issue:12

    Topics: Adult; Evoked Potentials, Somatosensory; Evoked Potentials, Visual; Humans; Male; Median Nerve; Nerv

1986
Tissue folates in fruit bats (Rousettus aegyptiacus) with nitrous oxide-induced vitamin B12 deficiency and neurological impairment.
    The British journal of nutrition, 1987, Volume: 58, Issue:3

    Topics: Animals; Brain; Chiroptera; Folic Acid; Liver; Methionine; Nervous System Diseases; Nitrous Oxide; S

1987
Methylation deficiency causes vitamin B12-associated neuropathy in the pig.
    Journal of neurochemistry, 1988, Volume: 51, Issue:6

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Homocysteine; Methylation; Nervo

1988
Succinylcholine, fasciculations and myoglobinaemia.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:2

    Topics: Age Factors; Anesthesia, General; Child; Child, Preschool; Drug Administration Schedule; Fasciculati

1986
Is nitrous oxide a dangerous anesthetic for vitamin B12-deficient subjects?
    JAMA, 1986, Mar-28, Volume: 255, Issue:12

    Topics: Adult; Erythrocyte Indices; Female; Hematocrit; Humans; Leukocyte Count; Middle Aged; Nervous System

1986
Occupational Hazards of anaesthesia. A panel discussion.
    Canadian Anaesthetists' Society journal, 1985, Volume: 32, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Anesthesia; Anesthesiology; Environmental Pollutants; Female; He

1985
Effects of enflurane, isoflurane, and nitrous oxide on somatosensory evoked potentials during fentanyl anesthesia.
    Anesthesiology, 1985, Volume: 62, Issue:5

    Topics: Anesthesia, General; Arm; Blood Pressure; Body Temperature; Enflurane; Evoked Potentials, Somatosens

1985
Pattern-reversal visual evoked potential in a case of nitrous oxide abuse and recovery.
    Clinical EEG (electroencephalography), 1985, Volume: 16, Issue:3

    Topics: Adult; Dentists; Diagnostic Errors; Evoked Potentials, Visual; Humans; Male; Multiple Sclerosis; Ner

1985
Plasma cortisol responses during neurosurgical and abdominal operations.
    British journal of anaesthesia, 1971, Volume: 43, Issue:12

    Topics: Abdomen; Adrenal Glands; Adult; Aged; Anesthesia, General; Betamethasone; Brain Neoplasms; Craniotom

1971