Page last updated: 2024-10-19

nitrous oxide and Muscle Contraction

nitrous oxide has been researched along with Muscle Contraction in 83 studies

Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"We studied the neuromuscular effects of both atracurium and mivacurium in a patient with Charcot-Marie-Tooth disease (CMTD) during nitrous oxide-oxygen-alfentanil-propofol anaesthesia."7.70Response to atracurium and mivacurium in a patient with Charcot-Marie-Tooth disease. ( Naguib, M; Samarkandi, AH, 1998)
"We describe the effect of repeated suxamethonium doses during propofol-fentanyl-N2O/O2 anaesthesia in a 29-year-old woman with active myasthenia gravis receiving chronic pyridostigmine therapy."7.69Response to suxamethonium during propofol-fentanyl-N2O/O2 anaesthesia in a patient with active myasthenia gravis receiving long-term anticholinesterase therapy. ( Booij, LH; Robertson, EN; Vanlinthout, LE, 1994)
"To investigate the relationship between total body weight (TBW) or body mass index (BMI) and atracurium reversal time."3.70Antagonism of atracurium-induced block in obese patients. ( Kirkegaard-Nielsen, H; Lindholm, P; Petersen, HS; Severinsen, IK, 1998)
"We studied the neuromuscular effects of both atracurium and mivacurium in a patient with Charcot-Marie-Tooth disease (CMTD) during nitrous oxide-oxygen-alfentanil-propofol anaesthesia."3.70Response to atracurium and mivacurium in a patient with Charcot-Marie-Tooth disease. ( Naguib, M; Samarkandi, AH, 1998)
" Neuromuscular blockade was induced and maintained with atracurium."3.70New equipment for neuromuscular transmission monitoring: a comparison of the TOF-Guard with the Myograph 2000. ( Helbo-Hansen, HS; Kirkegaard-Nielsen, H; Lindholm, P; Pedersen, HS; Schmidt, MB; Severinsen, IK, 1998)
"We describe the effect of repeated suxamethonium doses during propofol-fentanyl-N2O/O2 anaesthesia in a 29-year-old woman with active myasthenia gravis receiving chronic pyridostigmine therapy."3.69Response to suxamethonium during propofol-fentanyl-N2O/O2 anaesthesia in a patient with active myasthenia gravis receiving long-term anticholinesterase therapy. ( Booij, LH; Robertson, EN; Vanlinthout, LE, 1994)
"An in vitro constant-flow, alternatively constant-pressure, perfusion method for studying microvascular myogenic responsiveness in otherwise intact rat hindquarters was used to explore how three types of influences affect the pressure-flow induced enhancements of myogenic tone: (1) Changes of potassium concentration over the range 2-50 mmol; (2) Whether myogenic responsiveness, which is fairly weak during these conditions of high shear rates, is enhanced by blockade of endothelial prostacyclin and nitrous oxide formation; (3) Whether some of the drawbacks of the constant-flow technique, like rapid edema formation, is offset by a constant-pressure variant."3.68Myogenic responsiveness in rat hindquarter vessels during constant-flow and constant-pressure perfusion in vitro; effects of various potassium concentrations and of endothelial nitrous oxide blockade. ( Folkow, B; Johnsson, E; Karlström, G, 1991)
" Because mild hypothermia is common during general anesthesia, the authors sought to determine the relationship between the core temperature, adductor pollicis muscle temperature, and the twitch response of the adductor pollicis muscle, during isoflurane anesthesia in 15 patients undergoing elective surgery in which muscle relaxants were not required."3.67The relationship between adductor pollicis twitch tension and core, skin, and muscle temperature during nitrous oxide-isoflurane anesthesia in humans. ( Caldwell, JE; Heier, T; Kitts, JB; Miller, RD; Sessler, DI, 1989)
"A two years, ten months old male with dermatomyositis was anaesthetized with enflurane, nitrous oxide and oxygen by mask followed by intravenous succinylcholine to facilitate endotracheal intubation."3.67Anaesthetic management of a child with dermatomyositis. ( Finholt, DA; Johns, RA; Stirt, JA, 1986)
"Rocuronium has minimal side effects, provides conditions more suitable for rapid tracheal intubation, and is associated with a shorter clinical duration than atracurium."2.69Comparison of neuromuscular effects, efficacy and safety of rocuronium and atracurium in ambulatory anaesthesia. ( Estafanous, FG; Knapik, AL; Maurer, WG; Whalley, DG, 1998)
"Mivacurium infusion was titrated to give a 90% block of first twitch height."2.68Recovery from mivacurium block with or without anticholinesterase following continuous infusion in obstetric patients. ( Chan, AM; Hui, TW; Jan, GS; Lo, JW; Tong, WN, 1996)
"The mivacurium infusion rate was adjusted to maintain single twitch depression at 95 +/- 4% of control."2.68Prolonged mivacurium infusion in young and elderly adults. ( Chakravorti, S; Cook, DR; Denman, W; Goudsouzian, N; Schwartz, A; Yang, HS, 1997)
"Mivacurium is a new short-acting competitive neuromuscular blocking agent."2.66Continuous infusion of mivacurium in children. ( Alifimoff, JK; Goudsouzian, NG, 1989)
"We were interested in determining the dose-response relationship of atracurium in children (2-10 yr) during nitrous oxide-isoflurane anesthesia (1%) and the atracurium infusion rate required to maintain about 95% neuromuscular blockade during nitrous oxide-halothane (0."2.66Atracurium infusion requirements in children during halothane, isoflurane, and narcotic anesthesia. ( Brandom, BW; Cook, DR; Fehr, B; Lineberry, CG; Rudd, GD; Woelfel, SK, 1985)
"In this article the pathophysiology of malignant hyperthermia, its signs, symptoms and treatment as well as safe anesthetic agents for individuals susceptible to malignant hyperthermia are discussed."2.42[Malignant hyperthermia]. ( Glahn, KP, 2003)
"A rigorous study of the dose-response relation of rapacuronium has, to our knowledge, yet to be performed."1.31Dose-response and onset/offset characteristics of rapacuronium. ( Flores, F; Ghori, K; Klewicka, MM; Kopman, AF; Neuman, GG, 2000)
" Dilations to sodium nitroprusside and C-type natriuretic peptide were significantly reduced (by 10+/-2% and 35+/-6%), whereas dose-response curves for papaverine and ACh were shifted to the right, despite unchanged increases in endothelial Ca(2+) after ACh."1.31Oxidized LDL increases the sensitivity of the contractile apparatus in isolated resistance arteries for Ca(2+) via a rho- and rho kinase-dependent mechanism. ( Bolz, SS; de Wit, C; Derwand, R; Galle, J; Pohl, U, 2000)
"Nitrous oxide has a short-acting suppressant effect on the pressure generating capacity of the diaphragm in healthy humans."1.31Depression of diaphragm contractility by nitrous oxide in humans. ( Clément, A; Cordingley, J; Fauroux, B; Hart, N; Lofaso, F; Moxham, J; Polkey, MI, 2002)
"Neostigmine was administered at either 10% recovery of the twitch height (TH10) at the adductor pollicis muscle (n = 14) or upon reappearance of the first response at the orbicularis oculi muscle (OO1) after train-of-four (TOF) stimulation (n = 16), the latter representing a deeper degree of neuromuscular blockade."1.29Effect of neostigmine at different levels of mivacurium-induced neuromuscular blockade. ( Baras, E; Camatte, S; Chandon, M; Just, B; Lienhart, A; Trévien, V, 1995)
"3 to 19 years old were studied to determine the individual dose-response curves and the maintenance requirements of alcuronium during N2O-O2-opioid anaesthesia."1.28Maintenance requirement of alcuronium in paediatric patients. ( Brown, TC; Meretoja, OA, 1990)
" They then compared these dose-response relationships with values obtained for adults (greater than 18 years old) under comparable anesthetic conditions."1.27Neuromuscular effects of vecuronium (ORG NC45) in infants and children during N2O, halothane anesthesia. ( Fisher, DM; Miller, RD, 1983)
" The dose-response curve was shifted significantly to the left during nitrous oxide-isoflurane anaesthesia (ED50 0."1.27Neuromuscular and cardiovascular effects of atracurium during nitrous oxide-fentanyl and nitrous oxide-isoflurane anaesthesia. ( Fahey, MR; Miller, RD; Rupp, SM, 1983)
" The dose-response curve for vecuronium was determined after the injection of a single bolus (40, 55 or 70 micrograms kg-1) to 33 patients."1.27Clinical pharmacology of vecuronium in children. Studies during nitrous oxide and halothane in oxygen anaesthesia. ( da Silva, GL; Delleur, MM; Loose, JP; Meistelman, C; Saint-Maurice, C, 1986)
"This study was performed to determine the potency of succinylcholine using the single-dose technique, and to test the ability of the cumulative dose technique for generating dose-response data."1.27Dose-response curves for succinylcholine: single versus cumulative techniques. ( Bevan, DR; Donati, F; Smith, CE, 1988)
" Group B (n = 10), H24 (n = 5), and H72 (n = 5) were anesthetized with sodium thiamylal (B) or halothane and N2O (H24, H72) for 3 h, during which a dose-response curve to histamine was obtained."1.27Prolonged hyporesponsiveness of airway smooth muscle to histamine following general anesthesia. ( Amyot, R; Chapleau, D; Couture, J; Michoud, MC; St-Jean, S, 1986)
"There were six recurrences, five of which could be attributed to inadequate sphincterotomy."1.25Conservative management of haemorrhoids. Part I: injection, freezing and ligation. ( Alexander-Williams, J; Crapp, AR, 1975)

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-199052 (62.65)18.7374
1990's26 (31.33)18.2507
2000's5 (6.02)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glahn, KP1
SCOGGIN, WA1
MCGAUGHEY, HS1
JOHNSON, WL1
THORNTON, WN1
Fahey, MR3
Morris, RB1
Miller, RD6
Sohn, YJ1
Cronnelly, R1
Gencarelli, P1
Fisher, DM1
Vitez, TS1
Difrancesco, LV1
Takatsuka, K1
Miyamoto, S1
Tamiya, T1
Gotoh, Y1
Rupp, SM1
Stirt, JA2
Katz, RL3
Murray, AL1
Schehl, DL1
Lee, C2
Donati, F3
Bevan, DR3
Takita, K1
Goda, Y1
Kemmotsu, O1
Mashio, H1
Okuyama, A1
Ito, Y1
Sakamoto, H1
Kawahigashi, H1
Kaplan, RF1
Garcia, M1
Hannallah, RS1
Vanlinthout, LE1
Robertson, EN1
Booij, LH1
Trévien, V1
Lienhart, A1
Just, B1
Chandon, M1
Baras, E1
Camatte, S1
Scheiber, G1
Ribeiro, FC1
Marichal, A1
Bredendiek, M1
Renzing, K1
Eiken, O1
Tesch, PA1
Mejkavic, IB1
Martínez, MC1
Muller, B1
Stoclet, JC1
Andriantsitohaina, R1
Kim, DW1
Joshi, GP1
White, PF2
Johnson, ER1
Lepage, JY1
Malinovsky, JM1
Malinge, M1
Lechevalier, T1
Dupuch, C1
Cozian, A1
Pinaud, M1
Souron, R1
Jan, GS1
Tong, WN1
Chan, AM1
Hui, TW1
Lo, JW1
Saitoh, Y2
Koitabashi, Y1
Makita, K2
Tanaka, H2
Amaha, K2
Goudsouzian, N1
Chakravorti, S1
Denman, W1
Schwartz, A1
Yang, HS1
Cook, DR3
Kirkegaard-Nielsen, H3
Lindholm, P3
Petersen, HS1
Severinsen, IK3
Naguib, M2
Samarkandi, AH1
Brandom, BW2
Woelfel, SK2
Ference, A1
Dayal, B1
Kerls, S1
Dutton, RC1
Smith, WD1
Bennett, HL1
Archer, S1
Smith, NT1
Helbo-Hansen, HS1
Pedersen, HS2
Schmidt, MB1
Fujii, Y2
Whalley, DG1
Maurer, WG1
Knapik, AL1
Estafanous, FG1
Heier, T3
Hetland, S1
Kopman, AF1
Klewicka, MM1
Ghori, K1
Flores, F1
Neuman, GG1
Bolz, SS1
Galle, J1
Derwand, R1
de Wit, C1
Pohl, U1
Fauroux, B1
Cordingley, J1
Hart, N1
Clément, A1
Moxham, J1
Lofaso, F1
Polkey, MI1
Hoshi, T1
Toyooka, H1
Sugai, N2
Hughes, R3
Payne, JP3
Ingram, GS1
Baraka, A1
Krahwinkel, DJ1
Sawyer, DC1
Eyster, GE1
Bender, G1
Alexander-Williams, J1
Crapp, AR1
Worsley, R1
Pühringer, FK1
Khuenl-Brady, KS1
Koller, J1
Mitterschiffthaler, G1
Vinet, R1
Brieva, C1
Pinardi, G1
Penna, M1
Johnsson, E1
Folkow, B1
Karlström, G1
Fiset, P1
Balendran, P1
Meretoja, OA1
Brown, TC1
Caldwell, JE2
Kitts, JB2
Lynam, DP1
Alifimoff, JK1
Goudsouzian, NG1
Engbaek, J1
Ostergaard, D1
Viby-Mogensen, J1
Skovgaard, LT1
Sessler, DI1
Watcha, MF1
Meistelman, C1
Loose, JP1
Saint-Maurice, C1
Delleur, MM1
da Silva, GL1
O'Hara, DA1
Fragen, RJ1
Shanks, CA2
Smith, CE1
Farag, HM1
Gyasi, H1
Ibrahim, AW1
Rudd, GD1
Fehr, B1
Lineberry, CG1
Amyot, R1
Michoud, MC1
St-Jean, S1
Chapleau, D1
Couture, J1
Condon, RE1
Cowles, V1
Ekbom, GA1
Schulte, WJ1
Hess, G1
Johns, RA1
Finholt, DA1
Norman, J2
Koiwa, S1
Kawazoe, T1
Takiguchi, M1
Takino, Y1
Sekiguchi, H1
Luchi, RJ1
Kritcher, EM1
Epstein, RA2
Wyte, SR1
Jackson, SH2
Sitter, S1
Heisterkamp, DV2
Skovsted, P2
Cohen, PJ2
Schuh, FT1
Viguera, MG1
Terry, RN1
Davies, JM1
Hogg, MI1
Rosen, M1
Harrison, GA1
Crane, LA1
Gootman, NL1
Gootman, PM1
Eger, EI1
Way, WL1
Stevens, WC1
Dolan, WM1
Gil-Rodriguez, JA1
Hill, DW1
Lundberg, S1
Blackburn, JP1
Conway, CM1
Leigh, JM1
Lindop, MJ1
Reitan, JA1
Hauge, A1
Treshchinskiĭ, AI1
Iamkovoĭ, IT1
Dretchen, K1
Ghoneim, MM1
Long, JP1
Wuschech, H1
Kempe, G1
Koschorek, H1
Ahrendt, E1
Platzek, S1
Freund, FG1
Munson, ES1
Maier, WR1
Caton, D1
Seed, RF1
de Jong, RH1
Robles, R1
Morikawa, KI1
Lundborg, RO1
Milde, JH1
Theye, RA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
INVIBO: Evaluation of the Feasibility and Tolerance of an Intubation Procedure Performed by Means of the Bonfils Fiberscope in Awake Patients With Predicted Difficult Intubation in the Context of ENT Cancer Surgery[NCT01070537]Phase 241 participants (Actual)Interventional2008-02-29Completed
The Effectiveness of Neostigmine on the Recovery of Rocuronium-Induced Neuromuscular Blockade: A Comparison Between Partial Dose and TOF Ratio-Based Adjustment Dose[NCT03058263]Phase 1/Phase 266 participants (Actual)Interventional2016-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nitrous oxide and Muscle Contraction

ArticleYear
[Malignant hyperthermia].
    Ugeskrift for laeger, 2003, Apr-21, Volume: 165, Issue:17

    Topics: Anesthetics, Inhalation; Dantrolene; Diagnosis, Differential; Genetic Predisposition to Disease; Hum

2003

Trials

17 trials available for nitrous oxide and Muscle Contraction

ArticleYear
Potentiation of succinylcholine phase II block with isoflurane.
    Anesthesiology, 1983, Volume: 58, Issue:6

    Topics: Adult; Drug Synergism; Female; Fentanyl; Humans; Infusions, Parenteral; Isoflurane; Male; Methyl Eth

1983
Intubating conditions and onset of action after rocuronium, vecuronium, and atracurium in young children.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:2

    Topics: Androstanols; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Child; Child, Preschool

1996
Interactions between mivacurium, rocuronium, and vecuronium during general anesthesia.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:4

    Topics: Adult; Androstanols; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Desflur

1996
Recovery from mivacurium block with or without anticholinesterase following continuous infusion in obstetric patients.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:5

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intrav

1996
Train-of-four and double burst stimulation fade at the great toe and thumb.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:4

    Topics: Adult; Analysis of Variance; Anesthetics, Inhalation; Anesthetics, Intravenous; Electric Stimulation

1997
Prolonged mivacurium infusion in young and elderly adults.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:9

    Topics: Adolescent; Adult; Aged; Aging; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inh

1997
Craniofacial electromyogram activation response: another indicator of anesthetic depth.
    Journal of clinical monitoring and computing, 1998, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Anesthesia, General; Anesthetics, Inhalation; Brain; Communication; Electric Stim

1998
Modified double burst stimulation of varying stimulating currents.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:7

    Topics: Adult; Analysis of Variance; Anesthesia Recovery Period; Anesthetics, Inhalation; Electric Stimulati

1998
Comparison of neuromuscular effects, efficacy and safety of rocuronium and atracurium in ambulatory anaesthesia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:10

    Topics: Adolescent; Adult; Aged; Alfentanil; Ambulatory Surgical Procedures; Androstanols; Anesthesia Recove

1998
The effect of suxamethonium alone and its interaction with gallamine on the indirectly elicited tetanic and single twitch contractions of skeletal muscle in man during anaesthesia.
    British journal of clinical pharmacology, 1975, Volume: 2, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthesia; Clinical Trials as Topic; Depression, Chemical; Drug Interactio

1975
Studies on dimethyl tubocurarine in anaesthetized man.
    British journal of anaesthesia, 1976, Volume: 48, Issue:10

    Topics: Anesthesia; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Heart Rate;

1976
Evaluation of the endotracheal intubating conditions of rocuronium (ORG 9426) and succinylcholine in outpatient surgery.
    Anesthesia and analgesia, 1992, Volume: 75, Issue:1

    Topics: Adult; Alfentanil; Ambulatory Surgical Procedures; Androstanols; Electric Stimulation; Humans; Intub

1992
Comparison of the neuromuscular block induced by mivacurium, suxamethonium or atracurium during nitrous oxide-fentanyl anaesthesia.
    British journal of anaesthesia, 1989, Volume: 63, Issue:4

    Topics: Anesthesia, General; Anesthesia, Inhalation; Atracurium; Fentanyl; Humans; Isoquinolines; Mivacurium

1989
Continuous infusion of mivacurium in children.
    British journal of anaesthesia, 1989, Volume: 63, Issue:5

    Topics: Anesthesia, Inhalation; Child; Fentanyl; Halothane; Humans; Infant; Infusions, Intravenous; Isoquino

1989
Comparison of visual and measured train-of-four recovery after vecuronium-induced neuromuscular blockade using two anaesthetic techniques.
    British journal of anaesthesia, 1986, Volume: 58, Issue:11

    Topics: Anesthesia, General; Anesthesia, Inhalation; Enflurane; Female; Humans; Male; Muscle Contraction; Ne

1986
Atracurium infusion requirements in children during halothane, isoflurane, and narcotic anesthesia.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:5

    Topics: Anesthesia, General; Atracurium; Child; Child, Preschool; Dose-Response Relationship, Drug; Fentanyl

1985
Comparative neuromuscular effects of Forane and halothane alone and in combination with d-tubocurarine in man.
    Anesthesiology, 1971, Volume: 35, Issue:1

    Topics: Adult; Anesthetics; Carbon Dioxide; Clinical Trials as Topic; Ethers; Halothane; Humans; Hydrocarbon

1971

Other Studies

65 other studies available for nitrous oxide and Muscle Contraction

ArticleYear
UTERINE CONTRACTILITY IN PRIMATES: A COMPARATIVE STUDY.
    Surgical forum, 1963, Volume: 14

    Topics: Animals; Cyclopropanes; Diphenylacetic Acids; Ether; Female; Haplorhini; Humans; Magnesium; Meperidi

1963
Clinical pharmacology of ORG NC45 (NorcuronTM): a new nondepolarizing muscle relaxant.
    Anesthesiology, 1981, Volume: 55, Issue:1

    Topics: Adult; Aged; Anesthesia, Inhalation; Halothane; Humans; Middle Aged; Muscle Contraction; Neostigmine

1981
Neuromuscular effects of vecuronium (ORG NC45) in infants and children during N2O, halothane anesthesia.
    Anesthesiology, 1983, Volume: 58, Issue:6

    Topics: Adolescent; Adult; Aging; Anesthesia, Inhalation; Child; Child, Preschool; Electromyography; Halotha

1983
Reversal of combination nondepolarized neuromuscular block.
    Anesthesia and analgesia, 1983, Volume: 62, Issue:12

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Electric Stimulation; Humans; Middle Aged; Muscle Cont

1983
[Effects of anesthetics (fluothane and nitrous oxide) and analgesics (diazepam and pentazocine) on the intracystic pressure curves].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1983, Volume: 74, Issue:3

    Topics: Analgesics; Child; Child, Preschool; Diazepam; Female; Halothane; Humans; Male; Muscle Contraction;

1983
Neuromuscular and cardiovascular effects of atracurium during nitrous oxide-fentanyl and nitrous oxide-isoflurane anaesthesia.
    British journal of anaesthesia, 1983, Volume: 55 Suppl 1

    Topics: Anesthesia, General; Atracurium; Blood Pressure; Dose-Response Relationship, Drug; Fentanyl; Heart R

1983
Modification of atracurium blockade by halothane and by suxamethonium. A review of clinical experience.
    British journal of anaesthesia, 1983, Volume: 55 Suppl 1

    Topics: Adolescent; Adult; Anesthesia, General; Atracurium; Drug Interactions; Halothane; Humans; Isoquinoli

1983
Secondary hyperparathyroidism shortens the action of vecuronium in patients with chronic renal failure.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:5 Pt 1

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Case-Control Studies; Electromyography; Female; Fen

1995
Mivacurium-induced neuromuscular blockade during sevoflurane and halothane anaesthesia in children.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:1

    Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Child, Preschool

1995
Response to suxamethonium during propofol-fentanyl-N2O/O2 anaesthesia in a patient with active myasthenia gravis receiving long-term anticholinesterase therapy.
    Anaesthesia, 1994, Volume: 49, Issue:6

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Dose-Response Relationship, Drug; Drug Resis

1994
Effect of neostigmine at different levels of mivacurium-induced neuromuscular blockade.
    Acta anaesthesiologica Scandinavica. Supplementum, 1995, Volume: 106

    Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Cholinesterase Inhibitor

1995
Effect of nitrous oxide on human skeletal muscle function.
    Acta anaesthesiologica Scandinavica, 1996, Volume: 40, Issue:4

    Topics: Adult; Humans; Male; Muscle Contraction; Muscle, Skeletal; Nitrous Oxide

1996
Alteration by lipopolysaccharide of the relationship between intracellular calcium levels and contraction in rat mesenteric artery.
    British journal of pharmacology, 1996, Volume: 118, Issue:5

    Topics: Analysis of Variance; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibi

1996
Pharmacodynamic dose-response and safety study of cisatracurium (51W89) in adult surgical patients during N2O-O2-opioid anesthesia.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; A

1996
Antagonism of atracurium-induced block in obese patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:1

    Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Body Mass Index; Body Weight;

1998
Response to atracurium and mivacurium in a patient with Charcot-Marie-Tooth disease.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:1

    Topics: Adolescent; Alfentanil; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenou

1998
Effects of cisatracurium in children during halothane-nitrous oxide anesthesia.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:3

    Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Antidotes; Atracurium;

1998
New equipment for neuromuscular transmission monitoring: a comparison of the TOF-Guard with the Myograph 2000.
    Journal of clinical monitoring and computing, 1998, Volume: 14, Issue:1

    Topics: Acceleration; Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhal

1998
A comparison of train-of-four monitoring: mechanomyography at the thumb vs acceleromyography at the big toe.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Acceleration; Adult; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous;

1999
Factors predicting atracurium reversal time.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:8

    Topics: Adult; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Ch

1999
Dose-response and onset/offset characteristics of rapacuronium.
    Anesthesiology, 2000, Volume: 93, Issue:4

    Topics: Adult; Alfentanil; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Dose-Resp

2000
Oxidized LDL increases the sensitivity of the contractile apparatus in isolated resistance arteries for Ca(2+) via a rho- and rho kinase-dependent mechanism.
    Circulation, 2000, Nov-07, Volume: 102, Issue:19

    Topics: Acetylcholine; Animals; Arteries; Calcium; Cricetinae; Endothelins; Intracellular Signaling Peptides

2000
Depression of diaphragm contractility by nitrous oxide in humans.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:2

    Topics: Administration, Inhalation; Adult; Anesthetics, Inhalation; Body Mass Index; Depression, Chemical; D

2002
Comparative effects of xenon and nitrous oxide on diaphragmatic contractility in dogs.
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:6

    Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Diaphragm; Dogs; Muscle Contraction; Nitrous

2002
Some characteristics of neuromuscular block in the respiratory musculature in anaesthetized man.
    Canadian Anaesthetists' Society journal, 1976, Volume: 23, Issue:2

    Topics: Abdominal Muscles; Adult; Diaphragm; Dose-Response Relationship, Drug; Halothane; Humans; Intercosta

1976
Potentiation of suxamethonium blockade by neostigmine in patients with atypical cholinesterase.
    British journal of anaesthesia, 1975, Volume: 47, Issue:3

    Topics: Anesthesia, Inhalation; Atropine; Child; Cholinesterases; Drug Synergism; Electric Stimulation; Halo

1975
Cardiopulmonary effects of fentanyl-droperidol, nitrous oxide, and atropine sulfate in dogs.
    American journal of veterinary research, 1975, Volume: 36, Issue:08

    Topics: Analgesia; Anesthesia; Animals; Atropine; Blood Pressure; Carbon Dioxide; Cardiac Output; Cardiovasc

1975
Conservative management of haemorrhoids. Part I: injection, freezing and ligation.
    Clinics in gastroenterology, 1975, Volume: 4, Issue:3

    Topics: Aged; Cicatrix; Cryosurgery; Defecation; Dilatation; Fecal Incontinence; Female; Hemorrhoids; Humans

1975
Tetanic force development of adductor pollicis muscle in anesthetized man.
    Journal of applied physiology, 1975, Volume: 39, Issue:5

    Topics: Adult; Aged; Anesthesia, General; Electric Stimulation; Humans; Male; Meperidine; Middle Aged; Muscl

1975
Modulation of alpha-adrenergic-induced contractions by endothelium-derived relaxing factor in rat aorta.
    General pharmacology, 1991, Volume: 22, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Clonidine; Endothelium, Vascular; In Vitro Tech

1991
Myogenic responsiveness in rat hindquarter vessels during constant-flow and constant-pressure perfusion in vitro; effects of various potassium concentrations and of endothelial nitrous oxide blockade.
    Acta physiologica Scandinavica, 1991, Volume: 142, Issue:3

    Topics: Animals; Blood Vessels; Edema; Endothelium, Vascular; Epoprostenol; Hindlimb; In Vitro Techniques; M

1991
Nitrous oxide potentiates vecuronium.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:4 Pt 2

    Topics: Adult; Anesthesia, General; Anesthesia, Inhalation; Dose-Response Relationship, Drug; Drug Synergism

1990
Maintenance requirement of alcuronium in paediatric patients.
    Anaesthesia and intensive care, 1990, Volume: 18, Issue:4

    Topics: Adolescent; Alcuronium; Anesthesia, Inhalation; Anesthesia, Intravenous; Child; Child, Preschool; Do

1990
Clinical recovery and train-of-four ratio measured mechanically and electromyographically following atracurium.
    Anesthesiology, 1989, Volume: 71, Issue:3

    Topics: Adult; Aged; Anesthesia Recovery Period; Atracurium; Diazepam; Droperidol; Electromyography; Female;

1989
The relationship between adductor pollicis twitch tension and core, skin, and muscle temperature during nitrous oxide-isoflurane anesthesia in humans.
    Anesthesiology, 1989, Volume: 71, Issue:3

    Topics: Anesthesia, Inhalation; Body Temperature; Electric Stimulation; Humans; Hypothermia; Hypothermia, In

1989
Failure of lower esophageal contractility to predict patient movement in children anesthetized with halothane and nitrous oxide.
    Anesthesiology, 1989, Volume: 71, Issue:5

    Topics: Adolescent; Anesthesia, General; Child; Dermatologic Surgical Procedures; Esophagus; Forecasting; Ha

1989
Clinical pharmacology of vecuronium in children. Studies during nitrous oxide and halothane in oxygen anaesthesia.
    British journal of anaesthesia, 1986, Volume: 58, Issue:9

    Topics: Anesthesia, Inhalation; Child; Child, Preschool; Dose-Response Relationship, Drug; Halothane; Hemody

1986
Dose-response curves for succinylcholine: single versus cumulative techniques.
    Anesthesiology, 1988, Volume: 69, Issue:3

    Topics: Adult; Analgesics, Opioid; Anesthesia, General; Dose-Response Relationship, Drug; Humans; Infusions,

1988
Anesthesia for a patient with eosinophilic myositis.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:8

    Topics: Adult; Anesthesia, General; Atracurium; Creatine Kinase; Eosinophilia; Fentanyl; Humans; Isoquinolin

1986
Prolonged hyporesponsiveness of airway smooth muscle to histamine following general anesthesia.
    Anesthesiology, 1986, Volume: 64, Issue:6

    Topics: Anesthesia, General; Animals; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Halothan

1986
Effects of halothane, enflurane, and nitrous oxide on colon motility.
    Surgery, 1987, Volume: 101, Issue:1

    Topics: Animals; Colon; Electrophysiology; Enflurane; Gastrointestinal Motility; Halothane; Macaca; Muscle C

1987
Anaesthetic management of a child with dermatomyositis.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:1

    Topics: Anesthesia, General; Child, Preschool; Dermatomyositis; Enflurane; Humans; Muscle Contraction; Neuro

1986
Effects of anaesthetics and their interactions with neuromuscular blocking agents in cats.
    British journal of anaesthesia, 1970, Volume: 42, Issue:10

    Topics: Animals; Blood Pressure; Cats; Chloralose; Drug Synergism; Electric Stimulation; Gallamine Triethiod

1970
Some effects of the steroidal muscle relaxant, dacuronium bromide, in anaesthetized patients.
    British journal of anaesthesia, 1971, Volume: 43, Issue:4

    Topics: Androstanes; Anesthesia, General; Blood Pressure; Electrophysiology; Halothane; Heart Rate; Humans;

1971
Relationship between pulmonary ventilation and serial changes in tetanus fading, with special reference to cumulative effects of pancuronium.
    Masui. The Japanese journal of anesthesiology, 1971, Volume: 20, Issue:4

    Topics: Adult; Aged; Androstanes; Anesthesia, Epidural; Electric Stimulation; Electrophysiology; Halothane;

1971
Drug effects on cardiac myosin adenosine triphosphatase activity.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:3

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Angiotensin II; Animals; Binding Sites; Calcium;

1967
The electromechanical response to stimulation by the Block-Aid Monitor.
    Anesthesiology, 1969, Volume: 30, Issue:1

    Topics: Anesthesia; Atropine; Electric Stimulation; Evoked Potentials; Halothane; Humans; Methods; Muscle Co

1969
The effects of small incremental doses of d-tubocurarine on neuromuscular transmission in anesthetized man.
    Anesthesiology, 1969, Volume: 30, Issue:5

    Topics: Adult; Anesthesia, Inhalation; Electric Stimulation; Female; Humans; Male; Methoxyflurane; Middle Ag

1969
Repetitive muscle depolarization from single indirect stimulation in anesthetized man.
    Journal of applied physiology, 1970, Volume: 28, Issue:4

    Topics: Anesthetics; Cyclopropanes; Electric Stimulation; Electromyography; Ethers; Ethyl Ethers; Halothane;

1970
The effect of a subthreshold dose of d-tubocurarine on the neuromuscular blocking action of succinylcholine in anesthetized man.
    Acta anaesthesiologica Scandinavica, 1974, Volume: 18, Issue:2

    Topics: Adult; Anesthesia, General; Cyclopropanes; Depression, Chemical; Dose-Response Relationship, Drug; D

1974
Upper limits of resistance of apparatus for inhalation analgesia during labour. Response of mothers to increasing apparatus resistance.
    British journal of anaesthesia, 1974, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Anesthesia, Inhalation; Anesthesia, Obstetrical; Female; Humans; Methoxyflurane;

1974
Mechanical measurement of neuromuscular blockade. A comparison between the force transducer and a simple muscle twitch monitor.
    British journal of anaesthesia, 1973, Volume: 45, Issue:1

    Topics: Electric Stimulation; Halothane; Humans; Manometry; Muscle Contraction; Neuromuscular Depolarizing A

1973
The effects of decamethonium (C-10) on blood pressure and heart rate in newborn piglets.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 208, Issue:1

    Topics: Acetylcholine; Aging; Anesthesia; Animals; Animals, Newborn; Blood Pressure; Carbon Dioxide; Decamet

1974
The correlation between haemodynamic changes and arterial blood halothane concentrations during halothane-nitrous oxide anaesthesia in the dog.
    British journal of anaesthesia, 1971, Volume: 43, Issue:11

    Topics: Anesthesia, Inhalation; Animals; Aorta; Blood Pressure; Cardiac Output; Cardiac Volume; Central Veno

1971
Pa CO2 and the pre-ejection period: the pa CO2 inotropy response curve.
    Anesthesiology, 1972, Volume: 37, Issue:3

    Topics: Adult; Age Factors; Aged; Anesthesia, General; Animals; Biomechanical Phenomena; Carbon Dioxide; Dog

1972
[Effect of anesthetics on the heart and blood vessels].
    Nordisk medicin, 1969, Oct-16, Volume: 82, Issue:42

    Topics: Anesthetics; Anesthetics, Local; Animals; Antihypertensive Agents; Barbiturates; Blood Circulation;

1969
The effect of general anaesthetics on the response to tetanic stimulus in man.
    British journal of anaesthesia, 1970, Volume: 42, Issue:6

    Topics: Adult; Anesthetics; Cyclopropanes; Electric Stimulation; Ethyl Ethers; Female; Humans; Methoxyfluran

1970
[Changes in the myocardial contractile function under the effects of the ganglionic blockader arfonad against a background of endotracheal nitrous oxide anesthesia].
    Vestnik khirurgii imeni I. I. Grekova, 1970, Volume: 105, Issue:10

    Topics: Adult; Anesthesia, Endotracheal; Female; Heart; Humans; Male; Middle Aged; Muscle Contraction; Nitro

1970
The interaction of diazepam with myoneural blocking agents.
    Anesthesiology, 1971, Volume: 34, Issue:5

    Topics: Acetylcholine; Adjuvants, Anesthesia; Adult; Animals; Cats; Chickens; Decamethonium Compounds; Diaze

1971
[Inorganic phosphate behavior during abdominal surgery under-intubation anesthesia (curaro-nitrous oxide anesthesia)].
    Zentralblatt fur Chirurgie, 1967, Volume: 92, Issue:26a Pt 1

    Topics: Anesthesia, Endotracheal; Colorimetry; Curare; Female; Humans; Male; Muscle Contraction; Muscles; Ni

1967
Tachyphylaxis to decamethonium and reversibility of the block by anticholinesterase drugs.
    Anesthesiology, 1969, Volume: 30, Issue:1

    Topics: Adult; Anesthesia, Endotracheal; Cholinesterase Inhibitors; Decamethonium Compounds; Electric Stimul

1969
Effects of halothane, cyclopropane and nitrous oxide on isolated human uterine muscle.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1969, Volume: 76, Issue:1

    Topics: Adult; Cyclopropanes; Female; Halothane; Humans; In Vitro Techniques; Middle Aged; Muscle Contractio

1969
A transatlantic studyof neuromuscular blockade.
    British journal of anaesthesia, 1969, Volume: 41, Issue:6

    Topics: Ethanol; Halothane; Humans; London; Muscle Contraction; New York; Nitrous Oxide; Succinylcholine; Th

1969
Actions of halothane and nitrous oxide on dorsal horn neurons ("The Spinal Gate").
    Anesthesiology, 1969, Volume: 31, Issue:3

    Topics: Anesthesia, General; Animals; Blood Pressure; Cats; Electrodes; Electroshock; Female; Foot; Halothan

1969
Effect of nitrous oxide on myocardial contractility of dogs.
    Canadian Anaesthetists' Society journal, 1966, Volume: 13, Issue:4

    Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Halothane; Heart; Heart Rate; Muscle Contraction; Nit

1966