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nitrous oxide and Lung Neoplasms

nitrous oxide has been researched along with Lung Neoplasms in 20 studies

Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.

Lung Neoplasms: Tumors or cancer of the LUNG.

Research Excerpts

ExcerptRelevanceReference
" The results indicated that two of the anesthetic drugs used during excision of the Lewis lung carcinoma (3LL) tumor, halothane and ketamine, decreased NK activity, whereas the other two, thiopental sodium and N2O, had no effect on NK activity in in vitro assays."3.67General anesthesia during excision of a mouse tumor accelerates postsurgical growth of metastases by suppression of natural killer cell activity. ( Feldman, M; Katzav, S; Segal, S; Shapiro, J, 1986)
"The syndrome is prevalent in elderly men, completely remitted with a small dose of steroid over a relatively short period, and has a benign clinical course."1.32[Anesthetic management for a patient with remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome]. ( Aoyama, K; Ishimura, H; Iwagaki, T; Kadoya, T; Takenaka, I; Terada, T, 2004)
" A cumulative dose-response curve for vecuronium was constructed, and pupillary changes in response to various noxious stimuli were evaluated with concomitant recording of the Spectral-Edge-Frequency 90% (SEF90; the frequency below which 90 percent of the EEG power is located)."1.30Vecuronium dose requirement and pupillary response in a patient with olivopontocerebellar atrophy (OPCA). ( Fukura, H; Goto, F; Kuroda, M; Morita, T; Saruki, N; Yoshikawa, D, 1998)
"Nitrous oxide was used after thoracotomy."1.28[Anesthetic management of a patient with diffuse pulmonary hamartoangiomyomatosis associated with spontaneous pneumothorax]. ( Kaneko, Y; Kobayashi, Y; Nagasaka, S; Shiratori, H; Shiratori, R; Uchiyama, M; Yamamoto, T, 1992)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19909 (45.00)18.7374
1990's4 (20.00)18.2507
2000's4 (20.00)29.6817
2010's3 (15.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Safdieh, JE1
Moré, JM1
Eclov, NCW1
Chung, MP1
Wynne, JF1
Shorter, JH1
Nelson, DD1
Hanlon, AL1
Burmeister, R1
Banos, P1
Maxim, PG1
Loo, BW1
Diehn, M1
Ko, R1
McRae, K1
Darling, G1
Waddell, TK1
McGlade, D1
Cheung, K1
Katz, J1
Slinger, P1
Bertoletti, L1
Robert, A1
Cottier, M1
Chambonniere, ML1
Vergnon, JM1
Järvholm, B1
Reuterwall, C1
POPOVIAN, IM1
Terada, T1
Ishimura, H1
Iwagaki, T1
Aoyama, K1
Takenaka, I1
Kadoya, T1
Shapiro, J2
Jersky, J1
Katzav, S2
Feldman, M2
Segal, S2
Wagner, RI1
Frid, IA2
Evtukhin, AI1
Barchuk, AS2
Shulga, NI1
Vagner, RI1
Evtiukhin, AI1
Shul'ga, NI1
Mitsuhata, H1
Horiguchi, Y1
Saitoh, J1
Saitoh, K1
Fukuda, H1
Hirabayasi, Y1
Togashi, H1
Shimizu, R1
Ziora, D1
Kozielski, J1
Oklek, K1
Kuroda, M1
Fukura, H1
Saruki, N1
Yoshikawa, D1
Morita, T1
Goto, F1
Maiwand, MO1
Simpson, PM1
Nagasaka, S1
Shiratori, R1
Kaneko, Y1
Shiratori, H1
Kobayashi, Y1
Uchiyama, M1
Yamamoto, T1
Baden, JM1
Kundomal, YR1
Luttropp, ME1
Mazze, RI1
Kosek, JC1
Giesecke, AH1
Gerbershagen, HU1
Dortman, C1
Lee, D1
Kerr, JH1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
IPg2 Study - Left-sided Lung Isolation: Comparison of Twodevices[NCT02137291]40 participants (Actual)Observational2014-05-31Completed
Physiology of Lung Collapse Under One-Lung Ventilation: Underlying Mechanisms[NCT02919267]40 participants (Actual)Interventional2016-09-30Completed
Isolated Lung Collapse in Two Stages With Bronchial Blocker: Comparison With Double Lumen Tube[NCT01615263]40 participants (Actual)Interventional2012-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Quantification of Gas Volume Coming From Ambient Air Towards the Alveoli Space of the Non-ventilated Lung During OLV With the Use of DLT and BB.

(NCT02919267)
Timeframe: From the beginning of OLV until 60 minutes

Interventionmilliliters (mL) (Mean)
Gas Movement Quantification With Double-lumen Tube504
Gas Movement Quantification With Bronchial Blocker630

Measurement of Intra-pulmonary Pressure in the Non-ventilated Lung With the Use of DLT and BB

Intra-pulmonary pressure measured from initiation of OLV to pleural opening were similarly analyzed using a two-way ANOVA. Two experimental factors, one associated to the comparison between two groups (DLT versus BB), factor fixed and one associated to the comparison among results from the time periods (0 to 10 minutes), factor fixed with interaction terms between the fixed factors were defined. The data was analyzed using a repeated mixed model. An autoregressive covariance structure was used to consider the dependency among repeated measurements. (NCT02919267)
Timeframe: From the beginning until 10 minutes of OLV

,
InterventioncmH2O (Mean)
0 minutes1 minutes2 minutes3 minutes4 minutes5 minutes6 minutes7 minutes8 minutes9 minutes10 minutes
Intra-pulmonary Pressure Determination With Bronchial Blocker0-0.7-2.6-4.9-8.9-11.9-14.2-18.1-19.7-24.6-28.3
Intra-pulmonary Pressure Measurements With Double-lumen Tube0-1.1-2.4-3.7-5.2-6.9-8.8-10.7-13.6-16.3-20.6

Opinion on the Device

20 minutes after pleural opening, the thoracic surgeon will give his opinion on the lung isolation device that was used on his patient (double lumen tube or bronchial blocker). (NCT01615263)
Timeframe: 20 minutes after pleural opening

Interventionpercentage of right guess/opinion (Number)
Double Lumen Tube50
Bronchial Blocker22.2

Time to Obtain Complete Lung Collapse

For patients intubated with double lumen tube (DLT), clamping of the ipsilateral lumen without continuous positive airway pressure (CPAP) on the isolated lung will be done to allow lung collapse. The timer will be started at this moment and stopped 20 minutes after pleural opening. For patients of the bronchial blocker (BB) group, the first apnea period will of 30 seconds, keeping a pulse oximetry (SpO2) always over 97%, and under direct visualization with the FOB. Afterward, the cuff will be reflated and the timer will be started at this moment and stopped 20 minutes after pleural opening. For both groups, time of total lung collapse will be measured. (NCT01615263)
Timeframe: From the beginning of one lung ventilation to 20 minutes after pleural opening

Interventionminutes (Mean)
Double Lumen Tube47.8
Bronchial Blocker32.5

Use of Suction to Facilitate Lung Collapse

(NCT01615263)
Timeframe: Up to 5 minutes after surgery

Interventionparticipants (Number)
Double Lumen Tube0
Bronchial Blocker1

Quality of Lung Collapse

"Assessment of lung collapse by the thoracic surgeon at 0, 5, 10 and 20 minutes after pleural opening.Visual analog scale of the quality of lung collapse will be assessed as the following:~No lung collapse~Partial lung collapse, not satisfactory~Partial lung collapse, satisfactory~Complete lung collapse" (NCT01615263)
Timeframe: From pleural opening to 20 minutes after

,
Interventionpercentage of patients (Number)
Time 0, No lung collapseTime 0, Partial lung collapse, not satisfactoryTime 0, Partial lung collapse, satisfactoryTime 0, Complete lung collapseTime 5 min, No lung collapseTime 5 min, Partial lung collapse not satisfactoryTime 5 min Partial lung collapse, satisfactoryTime 5 min Complete lung collapseTime 10 min, No lung collapseTime 10 min Partial lung collapse not satisfactoryTime 10 min Partial lung collapse, satisfactoryTime 10 min Complete lung collapseTime 20 min, No lung collapseTime 20 min Partial lung collapse not satisfactoryTime 20 min Partial lung collapse, satisfactoryTime 20 min Complete lung collapse
Bronchial Blocker6175522063955003367002278
Double Lumen Tube1045301551065200106030055045

Reviews

2 reviews available for nitrous oxide and Lung Neoplasms

ArticleYear
Endobronchial cryosurgery.
    Chest surgery clinics of North America, 2001, Volume: 11, Issue:4

    Topics: Bronchial Diseases; Bronchoscopes; Bronchoscopy; Carbon Dioxide; Cryosurgery; Humans; Lung Neoplasms

2001
Physiological aspects of one-lung (endobronchial) anesthesia.
    International anesthesiology clinics, 1972,Winter, Volume: 10, Issue:4

    Topics: Aged; Anesthesia, Inhalation; Bronchi; Carbon Dioxide; Carcinoma, Bronchogenic; Cardiac Output; Fema

1972

Trials

3 trials available for nitrous oxide and Lung Neoplasms

ArticleYear
The use of air in the inspired gas mixture during two-lung ventilation delays lung collapse during one-lung ventilation.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:4

    Topics: Administration, Inhalation; Aged; Anesthetics, Inhalation; Female; Humans; Inhalation; Lung Neoplasm

2009
The use of air in the inspired gas mixture during two-lung ventilation delays lung collapse during one-lung ventilation.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:4

    Topics: Administration, Inhalation; Aged; Anesthetics, Inhalation; Female; Humans; Inhalation; Lung Neoplasm

2009
The use of air in the inspired gas mixture during two-lung ventilation delays lung collapse during one-lung ventilation.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:4

    Topics: Administration, Inhalation; Aged; Anesthetics, Inhalation; Female; Humans; Inhalation; Lung Neoplasm

2009
The use of air in the inspired gas mixture during two-lung ventilation delays lung collapse during one-lung ventilation.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:4

    Topics: Administration, Inhalation; Aged; Anesthetics, Inhalation; Female; Humans; Inhalation; Lung Neoplasm

2009
The use of air in the inspired gas mixture during two-lung ventilation delays lung collapse during one-lung ventilation.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:4

    Topics: Administration, Inhalation; Aged; Anesthetics, Inhalation; Female; Humans; Inhalation; Lung Neoplasm

2009
The use of air in the inspired gas mixture during two-lung ventilation delays lung collapse during one-lung ventilation.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:4

    Topics: Administration, Inhalation; Aged; Anesthetics, Inhalation; Female; Humans; Inhalation; Lung Neoplasm

2009
The use of air in the inspired gas mixture during two-lung ventilation delays lung collapse during one-lung ventilation.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:4

    Topics: Administration, Inhalation; Aged; Anesthetics, Inhalation; Female; Humans; Inhalation; Lung Neoplasm

2009
The use of air in the inspired gas mixture during two-lung ventilation delays lung collapse during one-lung ventilation.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:4

    Topics: Administration, Inhalation; Aged; Anesthetics, Inhalation; Female; Humans; Inhalation; Lung Neoplasm

2009
The use of air in the inspired gas mixture during two-lung ventilation delays lung collapse during one-lung ventilation.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:4

    Topics: Administration, Inhalation; Aged; Anesthetics, Inhalation; Female; Humans; Inhalation; Lung Neoplasm

2009
Accuracy and feasibility of electromagnetic navigated bronchoscopy under nitrous oxide sedation for pulmonary peripheral opacities: an outpatient study.
    Respiration; international review of thoracic diseases, 2009, Volume: 78, Issue:3

    Topics: Aged; Anesthetics, Inhalation; Bronchoscopy; Diagnostic Errors; Electromagnetic Fields; Female; Huma

2009
[Usefulness of cryoapplication for bleeding after needle biopsy during fiberoptic bronchoscopy].
    Pneumonologia i alergologia polska, 1997, Volume: 65, Issue:11-12

    Topics: Adult; Aerosol Propellants; Aged; Biopsy, Needle; Bronchoscopy; Cryotherapy; Female; Fiber Optic Tec

1997

Other Studies

15 other studies available for nitrous oxide and Lung Neoplasms

ArticleYear
Patient management problem.
    Continuum (Minneapolis, Minn.), 2014, Volume: 20, Issue:3 Neurolog

    Topics: Adenocarcinoma; Aged; Alcoholism; Anesthetics, Inhalation; Bariatric Surgery; Diabetes Mellitus, Typ

2014
Feasibility and potential utility of multicomponent exhaled breath analysis for predicting development of radiation pneumonitis after stereotactic ablative radiotherapy.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2014, Volume: 9, Issue:7

    Topics: Aged; Aged, 80 and over; Breath Tests; Carbon Dioxide; Carbon Monoxide; Feasibility Studies; Female;

2014
A comparison of occupational and non-occupational exposure to diesel exhausts and its consequences for studying health effects.
    Occupational and environmental medicine, 2012, Volume: 69, Issue:11

    Topics: Air Pollution; Environmental Exposure; Humans; Lung Neoplasms; Mining; Nitrous Oxide; Occupational E

2012
[OUR EXPERIENCE IN REDUCING COMPLICATIONS AND MORTALITY IN LOBECTOMY].
    Khirurgiia, 1964, Volume: 40

    Topics: Anesthesia; Anesthesia, Endotracheal; Echinococcosis; Echinococcosis, Pulmonary; Humans; Lung; Lung

1964
[Anesthetic management for a patient with remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:9

    Topics: Anesthesia, Epidural; Anesthesia, Inhalation; Arthritis; Arthritis, Rheumatoid; Carcinoma, Large Cel

2004
Anesthetic drugs accelerate the progression of postoperative metastases of mouse tumors.
    The Journal of clinical investigation, 1981, Volume: 68, Issue:3

    Topics: Anesthetics; Animals; Halothane; Liver Neoplasms; Lung Neoplasms; Male; Mice; Neoplasm Metastasis; N

1981
On the end results of surgical treatment of lung cancer patients depending on the type of anesthetic agent.
    Journal of surgical oncology, 1981, Volume: 18, Issue:1

    Topics: Adenocarcinoma; Aged; Anesthesia, General; Carcinoma; Carcinoma, Squamous Cell; Ether; Ethyl Ethers;

1981
[Effect of the type of anesthesia on the long-term results of surgical treatment of lung cancer patients].
    Voprosy onkologii, 1981, Volume: 27, Issue:11

    Topics: Adenocarcinoma; Anesthesia, General; Carcinoma, Squamous Cell; Ethyl Ethers; Halothane; Humans; Lung

1981
An anaphylactic reaction to topical fibrin glue.
    Anesthesiology, 1994, Volume: 81, Issue:4

    Topics: Administration, Topical; Aged; Anaphylaxis; Anesthesia, General; Anesthetics; Ethers; Female; Fibrin

1994
Vecuronium dose requirement and pupillary response in a patient with olivopontocerebellar atrophy (OPCA).
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:10

    Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Autonomic Nervous System; Dose-Response Rel

1998
Tracheal intubation with a Robertshaw tube via a tracheostomy.
    British journal of anaesthesia, 1976, Volume: 48, Issue:4

    Topics: Aged; Anesthesia, General; Humans; Intubation, Intratracheal; Lung Neoplasms; Male; Nitrous Oxide; P

1976
[Anesthetic management of a patient with diffuse pulmonary hamartoangiomyomatosis associated with spontaneous pneumothorax].
    Masui. The Japanese journal of anesthesiology, 1992, Volume: 41, Issue:5

    Topics: Adult; Anesthesia, Inhalation; Enflurane; Female; Humans; Lung Neoplasms; Lymphangiomyoma; Nitrous O

1992
Carcinogen bioassay of nitrous oxide in mice.
    Anesthesiology, 1986, Volume: 64, Issue:6

    Topics: Adenoma; Animals; Biological Assay; Body Weight; Female; Liver Neoplasms; Lung Neoplasms; Male; Mice

1986
General anesthesia during excision of a mouse tumor accelerates postsurgical growth of metastases by suppression of natural killer cell activity.
    Israel journal of medical sciences, 1986, Volume: 22, Issue:5

    Topics: Anesthesia, General; Anesthetics; Animals; Carcinoma; Female; Halothane; In Vitro Techniques; Ketami

1986
Comparison of the ventilating and injection bronchoscopes.
    Anesthesiology, 1973, Volume: 38, Issue:3

    Topics: Acidosis, Respiratory; Adult; Anesthesia, General; Anesthesia, Inhalation; Blood Pressure; Bronchosc

1973