nitrous oxide has been researched along with Leukemia in 9 studies
Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Use of nitrous oxide in pediatric leukemia patients at the same time as methotrexate use should be avoided especially as many suitable alternative anesthetic agents exist." | 7.83 | Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients. ( Baird, SF; Forster, VJ; Halsey, C; Mair, S; Skinner, R; van Delft, FW, 2016) |
| "Myelo-cytotoxicity of extended nitrous oxide (N2O) inhalation was described almost forty years ago and then incidentally applied already with temporary success for suppressing leukemia." | 4.78 | Anti-leukemic potential of methyl-cobalamin inactivation by nitrous oxide. ( Abels, J; Ermens, AA; Kroes, AC; Lindemans, J; Schoester, M; Spijkers, LJ; van Kapel, J, 1990) |
| "Use of nitrous oxide in pediatric leukemia patients at the same time as methotrexate use should be avoided especially as many suitable alternative anesthetic agents exist." | 3.83 | Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients. ( Baird, SF; Forster, VJ; Halsey, C; Mair, S; Skinner, R; van Delft, FW, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fluegge, K | 2 |
| Forster, VJ | 1 |
| van Delft, FW | 1 |
| Baird, SF | 1 |
| Mair, S | 1 |
| Skinner, R | 1 |
| Halsey, C | 1 |
| HINGSON, RA | 1 |
| EDWARDS, WB | 1 |
| DOAN, CA | 1 |
| LASSEN, HC | 1 |
| KRISTENSEN, HS | 1 |
| Harling, DW | 1 |
| Harrison, DA | 1 |
| Dorman, T | 1 |
| Barker, I | 1 |
| Zack, M | 1 |
| Adami, HO | 1 |
| Ericson, A | 1 |
| Abels, J | 2 |
| Kroes, AC | 2 |
| Ermens, AA | 2 |
| van Kapel, J | 1 |
| Schoester, M | 2 |
| Spijkers, LJ | 1 |
| Lindemans, J | 2 |
| van Lom, K | 1 |
1 review available for nitrous oxide and Leukemia
| Article | Year |
|---|---|
Anti-leukemic potential of methyl-cobalamin inactivation by nitrous oxide.
Topics: Animals; Humans; Leukemia; Nitrous Oxide; Vitamin B 12 | 1990 |
1 trial available for nitrous oxide and Leukemia
| Article | Year |
|---|---|
A comparison of thiopentone-isoflurane anaesthesia vs propofol infusion in children having repeat minor haematological procedures.
Topics: Acute Disease; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Biopsy, Nee | 1997 |
7 other studies available for nitrous oxide and Leukemia
| Article | Year |
|---|---|
Exploring the potential confounder of nitrogen fertilizers in the relationship between pesticide exposures and risk of leukemia: a Poisson regression with two-way fixed-effects analysis.
Topics: Air Pollutants; Fertilizers; Glycine; Glyphosate; Humans; Leukemia; Longitudinal Studies; Nitrous Ox | 2017 |
Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients.
Topics: Antimetabolites, Antineoplastic; Child; Child, Preschool; Drug Interactions; Female; Humans; Leukemi | 2016 |
Newborn mortality and morbidity with continuous caudal analgesia; an analysis of cases in New York, Philadelphia and Memphis, with controls.
Topics: Analgesia; Anesthesia; Anesthesia, Spinal; Disease; Humans; Infant; Infant Mortality; Infant, Newbor | 1948 |
APLASTIC VERSUS HYPERPLASTIC BLOOD DYSCRASIAS.
Topics: Anemia; Anemia, Aplastic; Anti-Bacterial Agents; Benzene; Bone Marrow Diseases; Chlorpromazine; Coba | 1964 |
Remission in chronic myeloid leucaemia following prolonged nitrous oxide inhalation.
Topics: Humans; Leukemia; Leukemia, Myeloid; Nitrous Oxide | 1959 |
Maternal and perinatal risk factors for childhood leukemia.
Topics: Child; Child, Preschool; Cleft Palate; Female; Fetus; Humans; Infant; Infant, Newborn; Jaundice, Neo | 1991 |
Effect of cobalamin inactivation on folate metabolism of leukemic cells.
Topics: Bone Marrow; Cell Line; Deoxyuridine; Female; Folic Acid; Humans; Leukemia; Male; Methotrexate; Nitr | 1988 |