nitrous oxide has been researched along with Laryngeal Spasm in 23 studies
Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intranasal dexmedetomidine and midazolam are equally effective in decreasing anxiety upon separation from parents; however, midazolam is superior in providing satisfactory conditions during mask induction." | 5.16 | Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia. ( Akin, A; Aksu, R; Altuntas, R; Bayram, A; Boyaci, A; Esmaoglu, A; Tosun, Z, 2012) |
| "The frequencies of laryngospasm and coughing of any severity after desflurane were greater than those after isoflurane (13% vs 5% and 26% vs 14%, respectively) (P < 0." | 2.75 | Airway responses to desflurane during maintenance of anesthesia and recovery in children with laryngeal mask airways. ( Betts, E; Deutsch, J; Ehlers, M; Hammer, GB; Khalil, SN; Lerman, J; Trillo, R; Verghese, S, 2010) |
| "Isoflurane was compared with sevoflurane in terms of rapidity, efficacy, safety and acceptability of induction." | 2.69 | Single vital capacity inhalational anaesthetic induction in adults--isoflurane vs sevoflurane. ( Lee, TL; Pua, HL; Ti, LK, 1998) |
| "The presence of gagging, coughing, laryngospasm and movement was noted and graded." | 2.67 | Patient response to laryngeal mask insertion after induction of anaesthesia with propofol or thiopentone. ( Carey, M; Kirby, F; Power, M; Scanlon, P, 1993) |
| "Desflurane was used for maintenance of anesthesia." | 1.39 | Minimum alveolar concentration of desflurane with caudal analgesia for laryngeal mask airway removal in anesthetized children. ( Ghai, B; Makkar, JK; Wig, J, 2013) |
| "Following the scout scan, severe laryngospasm developed." | 1.37 | Computed tomography changes of alveoli and airway collapse after laryngospasm. ( Erb, TO; Johnson, J; Keating, M; von Ungern-Sternberg, BS, 2011) |
| " We characterize the fasting status of patients receiving procedural sedation and analgesia in a pediatric ED and assess the relationship between fasting status and adverse events." | 1.32 | Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department. ( Agrawal, D; Gupta, R; Krauss, B; Manzi, SF, 2003) |
| "Moderate-to-severe laryngospasm (49%) and moderate-to-severe coughing (58%) occurred frequently during induction of anesthesia with desflurane; the incidence of these was not altered by premedication." | 1.28 | Induction and maintenance characteristics of anesthesia with desflurane and nitrous oxide in infants and children. ( Coté, CJ; Davis, PJ; Dinner, M; Fisher, DM; Hannallah, RS; Liu, LM; McGill, WA; Sarner, J; Welborn, LG; Zwass, MS, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (21.74) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 4 (17.39) | 29.6817 |
| 2010's | 8 (34.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Makkar, JK | 2 |
| Ghai, B | 2 |
| Wig, J | 2 |
| Babl, FE | 1 |
| Grindlay, J | 1 |
| Barrett, MJ | 1 |
| Smits, GJP | 1 |
| Thijssen, WAMH | 1 |
| Umesh, G | 1 |
| Jasvinder, K | 1 |
| Ramkumar, V | 1 |
| D'Eramo, EM | 3 |
| Bontempi, WJ | 1 |
| Howard, JB | 1 |
| Lerman, J | 1 |
| Hammer, GB | 1 |
| Verghese, S | 1 |
| Ehlers, M | 1 |
| Khalil, SN | 1 |
| Betts, E | 1 |
| Trillo, R | 1 |
| Deutsch, J | 1 |
| Keating, M | 1 |
| Johnson, J | 1 |
| Erb, TO | 1 |
| von Ungern-Sternberg, BS | 1 |
| Bhardwaj, N | 1 |
| Akin, A | 1 |
| Bayram, A | 1 |
| Esmaoglu, A | 1 |
| Tosun, Z | 1 |
| Aksu, R | 1 |
| Altuntas, R | 1 |
| Boyaci, A | 1 |
| Agrawal, D | 1 |
| Manzi, SF | 1 |
| Gupta, R | 1 |
| Krauss, B | 1 |
| Galante, D | 1 |
| Pellico, G | 1 |
| Federico, A | 1 |
| Schiraldi, R | 1 |
| Matella, M | 1 |
| Milillo, R | 1 |
| Dambrosio, M | 1 |
| Cinnella, G | 1 |
| Scanlon, P | 1 |
| Carey, M | 1 |
| Power, M | 1 |
| Kirby, F | 1 |
| Harling, DW | 1 |
| Harrison, DA | 1 |
| Dorman, T | 1 |
| Barker, I | 1 |
| Ti, LK | 1 |
| Pua, HL | 1 |
| Lee, TL | 1 |
| Lanning, CF | 1 |
| Harmel, MH | 1 |
| Cibils, LA | 1 |
| Zwass, MS | 1 |
| Fisher, DM | 1 |
| Welborn, LG | 1 |
| Coté, CJ | 1 |
| Davis, PJ | 1 |
| Dinner, M | 1 |
| Hannallah, RS | 1 |
| Liu, LM | 1 |
| Sarner, J | 1 |
| McGill, WA | 1 |
| Jeppesen, K | 1 |
| Carugati, G | 1 |
| Fessl-Alemany, E | 1 |
| Stöcker, L | 1 |
| Taube, HD | 1 |
| Wessing, A | 1 |
| Noble, FP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Nebulized Midazolam, Dexmedetomidine, and Their Combination in Sedation of Preschoolers Undergoing Dental Treatment: A Randomized Clinical Trial[NCT03827408] | Phase 2 | 72 participants (Actual) | Interventional | 2017-11-27 | Completed | ||
| Effectiveness and Pulmonary Complications of Peri-Operative Laryngeal Mask Airway Used in Elderly Patients(POLMA-EP Trial): a Multi-center Randomized Controlled Clinical Trial[NCT02240901] | 2,900 participants (Actual) | Interventional | 2016-08-03 | Completed | |||
| Comparing the Efficacy Between Desflurane and Sevoflurane in Miantainance of Spontaneous General Anaesthesia Using Ambu Aura Gain in Paediatrics Patients[NCT04771962] | Phase 1/Phase 2 | 80 participants (Actual) | Interventional | 2020-01-01 | Completed | ||
| Effect of Head Position on Minimum Alveolar Concentration of Endotracheal Intubation（MACEI）of Sevoflurane in Children With Obstructive Airway[NCT03522402] | 38 participants (Anticipated) | Interventional | 2018-01-01 | Enrolling by invitation | |||
| Evaluating Stress Response and Anxiety Score in Paediatric Patients Sedated With Intranasal Dexmedetomidine[NCT04526652] | Phase 2 | 60 participants (Actual) | Interventional | 2020-12-01 | Completed | ||
| Comparing Intranasal Dexmedetomidine With Oral Midazolam as Premedication for Older Children Undergoing General Anesthesia for Dental Rehabilitation[NCT02250703] | Phase 3 | 75 participants (Actual) | Interventional | 2014-09-30 | Completed | ||
| Do Patients Need Pre-Procedural Fasting for Coronary Artery Procedures?[NCT02562638] | 240 participants (Anticipated) | Interventional | 2015-10-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Level of sedation at separation from parents and at the time of mask induction will be measured on a scale of 0 to 4 (University of Michigan Sedation Scale)~University of Michigan Sedation Scale:~0 -Awake/Alert~1 -Minimally Sedated: Tired/sleepy, appropriate response to verbal conversation and/or sounds.~2- Moderately Sedated: Somnolent/sleeping, easily aroused with light tactile stimulation.~3 - Deeply Sedated: Deep sleep, arousable only with significant physical stimulation.~4 - Unarousable~Moderately and Deeply sedated: Satisfactory Awake, minimally sedate, unarousable: Unsatisfactory" (NCT02250703)
Timeframe: Day 0:Just before the patient will be brought to the operating room
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Satisfactory sedation on separation from parents | Unsatisfactory sedation on separation from parents | Satisfactory sedation on transfer to OR table | Unsatisfactory sedation on transfer to OR table | |
| Dexmedetomidine | 25 | 11 | 22 | 14 |
| Midazolam | 15 | 22 | 12 | 25 |
1 review available for nitrous oxide and Laryngeal Spasm
| Article | Year |
|---|---|
Ketamine anesthesia.
Topics: Anesthesia, General; Animals; Blood Pressure; Bronchial Spasm; Central Nervous System; Central Venou | 1975 |
5 trials available for nitrous oxide and Laryngeal Spasm
| Article | Year |
|---|---|
Airway responses to desflurane during maintenance of anesthesia and recovery in children with laryngeal mask airways.
Topics: Adolescent; Age Factors; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Inhalation; A | 2010 |
Airway responses to desflurane during maintenance of anesthesia and recovery in children with laryngeal mask airways.
Topics: Adolescent; Age Factors; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Inhalation; A | 2010 |
Airway responses to desflurane during maintenance of anesthesia and recovery in children with laryngeal mask airways.
Topics: Adolescent; Age Factors; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Inhalation; A | 2010 |
Airway responses to desflurane during maintenance of anesthesia and recovery in children with laryngeal mask airways.
Topics: Adolescent; Age Factors; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Inhalation; A | 2010 |
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2012 |
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2012 |
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2012 |
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2012 |
Patient response to laryngeal mask insertion after induction of anaesthesia with propofol or thiopentone.
Topics: Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Cough; Extremities; Female; Gagging; Head; H | 1993 |
A comparison of thiopentone-isoflurane anaesthesia vs propofol infusion in children having repeat minor haematological procedures.
Topics: Acute Disease; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Biopsy, Nee | 1997 |
Single vital capacity inhalational anaesthetic induction in adults--isoflurane vs sevoflurane.
Topics: Adolescent; Adult; Anesthesia, Closed-Circuit; Anesthesia, Inhalation; Anesthetics, Inhalation; Coug | 1998 |
17 other studies available for nitrous oxide and Laryngeal Spasm
| Article | Year |
|---|---|
Minimum alveolar concentration of desflurane with caudal analgesia for laryngeal mask airway removal in anesthetized children.
Topics: Airway Extubation; Analgesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Breath Holding; Child | 2013 |
Laryngospasm With Apparent Aspiration During Sedation With Nitrous Oxide.
Topics: Adolescent; Conscious Sedation; Emergency Service, Hospital; Humans; Hypnotics and Sedatives; Laryng | 2015 |
Laryngospasm With Apparent Aspiration During Sedation With Nitrous Oxide.
Topics: Anesthesia; Conscious Sedation; Humans; Laryngismus; Nitrous Oxide | 2016 |
Guideline for Monitoring and Management of Pediatric Patients Before, During, and After Sedation for Diagnostic and Therapeutic Procedures: Update 2016.
Topics: Airway Management; Airway Obstruction; Anesthesia, General; Anesthetics, Local; Apnea; Capnography; | 2016 |
Management of laryngospasm - our concerns and suggestions.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Humans; Infusions, Intravenous; Laryngismus; Nitrog | 2008 |
Anesthesia morbidity and mortality experience among Massachusetts oral and maxillofacial surgeons.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, Gene | 2008 |
Computed tomography changes of alveoli and airway collapse after laryngospasm.
Topics: Anesthesia, General; Anesthetics, Inhalation; Female; Humans; Infant; Laryngismus; Lung; Methyl Ethe | 2011 |
Minimum alveolar concentration of desflurane with fentanyl for laryngeal mask airway removal in anesthetized children.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Child, Preschool; Cou | 2012 |
Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department.
Topics: Adjuvants, Anesthesia; Analgesia; Anesthetics, Combined; Child; Child, Preschool; Chloral Hydrate; C | 2003 |
Postextubation adverse events in children undergoing general anesthesia.
Topics: Air Pressure; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Croup; Equip | 2007 |
Mortality and morbidity with outpatient anesthesia: the Massachusetts experience.
Topics: Aged; Ambulatory Care; Analgesics, Opioid; Anesthesia, Dental; Anesthesia, General; Anesthesia, Loca | 1999 |
Anesthesia for coelioscopy.
Topics: Abdomen; Anesthesia; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Local; Arrhythmias, Ca | 1975 |
Induction and maintenance characteristics of anesthesia with desflurane and nitrous oxide in infants and children.
Topics: Anesthesia, Inhalation; Atropine; Child; Child, Preschool; Cough; Desflurane; Diazepam; Halothane; H | 1992 |
Morbidity and mortality with outpatient anesthesia: the Massachusetts experience.
Topics: Aged; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, General; Anesthesia, Intraveno | 1992 |
[General anesthesia for outpatient dental treatment of children].
Topics: Ambulatory Care; Anesthesia, Dental; Anesthesia, General; Blood Pressure; Child; Child, Preschool; D | 1973 |
[General anaesthesia in ophthalmic surgery. 5 year report from the eye hospital Essen].
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Anest | 1973 |
Office experience with nitrous oxide-halothane anesthesia.
Topics: Anesthesia, Dental; Anesthesia, General; Atropine; Barbiturates; Blood Pressure Determination; Costs | 1967 |