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nitrous oxide and Encephalopathy, Toxic

nitrous oxide has been researched along with Encephalopathy, Toxic in 9 studies

Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.

Research Excerpts

ExcerptRelevanceReference
"Use of nitrous oxide in pediatric leukemia patients at the same time as methotrexate use should be avoided especially as many suitable alternative anesthetic agents exist."7.83Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients. ( Baird, SF; Forster, VJ; Halsey, C; Mair, S; Skinner, R; van Delft, FW, 2016)
"Use of nitrous oxide in pediatric leukemia patients at the same time as methotrexate use should be avoided especially as many suitable alternative anesthetic agents exist."3.83Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients. ( Baird, SF; Forster, VJ; Halsey, C; Mair, S; Skinner, R; van Delft, FW, 2016)
"Nitrous oxide is a commonly abused inhalant drug."2.43Nitrous oxide "whippit" abuse presenting with cobalamin responsive psychosis. ( Capasso, G; Mullin, P; Sethi, NK; Torgovnick, J, 2006)
"To date, chronic toxic encephalopathy (CTE) has never been described in operating room personnel."1.35Persistent cognitive functioning deficits in operating rooms: two cases. ( Dreyfus, E; Lehucher-Michel, MP; Tramoni, E, 2008)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's3 (33.33)29.6817
2010's4 (44.44)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Xiang, Y1
Li, L1
Ma, X1
Li, S1
Xue, Y1
Yan, P1
Chen, M1
Wu, J1
Johnson, K1
Mikhail, P1
Kim, MG1
Bosco, A1
Huynh, W1
Shah, K1
Murphy, C1
Löbel, U1
Trah, J1
Escherich, G1
Forster, VJ1
van Delft, FW1
Baird, SF1
Mair, S1
Skinner, R1
Halsey, C1
Nakao, S1
Nagata, A1
Masuzawa, M1
Miyamoto, E1
Yamada, M1
Nishizawa, N1
Shingu, K1
Sethi, NK1
Mullin, P1
Torgovnick, J1
Capasso, G1
Dreyfus, E1
Tramoni, E1
Lehucher-Michel, MP1
Haljamäe, H1

Reviews

3 reviews available for nitrous oxide and Encephalopathy, Toxic

ArticleYear
Recreational Nitrous Oxide Abuse: Prevalence, Neurotoxicity, and Treatment.
    Neurotoxicity research, 2021, Volume: 39, Issue:3

    Topics: Humans; Illicit Drugs; Neurotoxicity Syndromes; Nitrous Oxide; Recreational Drug Use; Substance-Rela

2021
[NMDA receptor antagonist neurotoxicity and psychotomimetic activity].
    Masui. The Japanese journal of anesthesiology, 2003, Volume: 52, Issue:6

    Topics: Anesthetics, Dissociative; Animals; Cerebral Cortex; Dizocilpine Maleate; Drug Synergism; GABA Modul

2003
Nitrous oxide "whippit" abuse presenting with cobalamin responsive psychosis.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2006, Volume: 2, Issue:2

    Topics: Adult; Hallucinogens; Humans; Male; Neurotoxicity Syndromes; Nitrous Oxide; Psychoses, Substance-Ind

2006

Other Studies

6 other studies available for nitrous oxide and Encephalopathy, Toxic

ArticleYear
Recreational nitrous oxide-associated neurotoxicity.
    Journal of neurology, neurosurgery, and psychiatry, 2018, Volume: 89, Issue:8

    Topics: Female; Humans; Neural Conduction; Neurotoxicity Syndromes; Nitrous Oxide; Spinal Cord; Treatment Ou

2018
Nitrous Oxide Toxicity: Case Files of the Carolinas Medical Center Medical Toxicology Fellowship.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2019, Volume: 15, Issue:4

    Topics: Academic Medical Centers; Aerosols; Humans; Male; Methionine; Middle Aged; Neurotoxicity Syndromes;

2019
Severe neurotoxicity following intrathecal methotrexate with nitrous oxide sedation in a child with acute lymphoblastic leukemia.
    Pediatric blood & cancer, 2015, Volume: 62, Issue:3

    Topics: Analgesics, Non-Narcotic; Child; Female; Humans; Immunosuppressive Agents; Injections, Spinal; Intra

2015
Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients.
    Cancer chemotherapy and pharmacology, 2016, Volume: 78, Issue:5

    Topics: Antimetabolites, Antineoplastic; Child; Child, Preschool; Drug Interactions; Female; Humans; Leukemi

2016
Persistent cognitive functioning deficits in operating rooms: two cases.
    International archives of occupational and environmental health, 2008, Volume: 82, Issue:1

    Topics: Anesthesiology; Anesthetics, Inhalation; Cognition Disorders; Female; Humans; Middle Aged; Neurotoxi

2008
[Risk of neurological injury after nitrous oxide anesthesia. Rare, but probably unreported adverse effect].
    Lakartidningen, 1999, Nov-03, Volume: 96, Issue:44

    Topics: Adverse Drug Reaction Reporting Systems; Air Pollutants, Occupational; Anesthetics, Inhalation; Huma

1999