Page last updated: 2024-10-19

nitrous oxide and Disease, Pulmonary

nitrous oxide has been researched along with Disease, Pulmonary in 39 studies

Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.

Research Excerpts

ExcerptRelevanceReference
"The investigation of gas exchange, central hemodynamics and real oxygen transport has shown expediency of using ether and fluothane as main anesthetic drugs in operations on the lungs in patients with a compensated form of chronic pulmonary respiratory insufficiency."3.67[Clinico-physiological substantiation of using various methods of anesthesia in operations on the lungs in patients with chronic respiratory insufficiency]. ( Zverev, VV, 1985)
"There are also possible effects on postoperative wound infections and neuropsychological function, although the multifactorial nature of these complications should be considered."2.50Nitrous oxide and perioperative outcomes. ( Kaye, AD; Ko, H; Urman, RD, 2014)
" The nature of these radicals, their cellular production as well as the defence mechanism which oppose their toxic effects are successively and briefly analysed."2.36[Pulmonary toxicity of free radicals of oxygen]. ( Housset, B; Junod, A, 1983)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199031 (79.49)18.7374
1990's4 (10.26)18.2507
2000's2 (5.13)29.6817
2010's2 (5.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ko, H1
Kaye, AD1
Urman, RD1
Sathitkarnmanee, T1
Tribuddharat, S1
Nonlhaopol, D1
Thananun, M1
Somdee, W1
Rytilä, P1
Malmberg, P1
GRAYSON, RR1
GAILITIS, J1
BURNS, LE1
NALLY, JB1
LEIB, GM1
DAVIS, WN1
BROWN, T1
McQUIGGAN, M1
SCHELL, HW1
Safar, P1
Karpinski, S1
Housset, B1
Junod, A1
Evans, MJ2
Wald, C1
Messina, FV1
Wynne, JW1
Gaston, B1
Drazen, JM1
Loscalzo, J1
Stamler, JS1
Okamoto, I1
Abe, M1
Shibata, K1
Shimizu, N1
Sakata, N1
Katsuragi, T1
Tanaka, K1
Keeri-Szanto, M1
Dekker, NP1
Cabral-Anderson, LJ1
Freeman, G1
Reil, B1
Podlesch, I1
Pallade, E1
Baktai, G1
Székely, E1
Márialigeti, T1
Kovács, L1
Russi, E1
Meulenbelt, J1
Sangster, B1
Smith, LL1
Stokke, T1
Burchardi, H1
Angerer, H1
Hensel, I1
Zverev, VV1
Borisko, AS1
Chernobrovyĭ, NP1
Carden, E1
Schwesinger, WB1
Ishikawa, K1
Miyazawa, K1
Tsuiki, K1
Matsunaga, A1
Haneda, T1
Knudsen, J1
Lomholt, N1
Wisborg, K1
Kerr, JH1
Stanley, TH1
Zikria, BA1
Anokhin, MI1
Hodgson, DC1
Collie, JA1
Thomford, NR1
Hamelberg, WE1
Wiederholt, WC1
Timchenko, IS1
Brakensiek, AL1
Bergman, NA1
Boutros, AR1
Weisel, M1
Martinez, LR1
Norlander, OP1
Kamiński, B1
Makowiecki, S1
Hamilton, WK1
Sokoll, MD1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Methods to Identify and Treat Severe Asthma Patients Project 1: GSNOR Phenotyping and GSNO Challenge[NCT03926741]Early Phase 160 participants (Anticipated)Interventional2019-04-30Recruiting
Investigation of Changes in the Levels of Exhaled NO and Eosinophil Blood Count in Patients Undergoing Thyroidectomy by Two Different Methods of General Anesthesia Maintenance[NCT02065635]60 participants (Actual)Interventional2014-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for nitrous oxide and Disease, Pulmonary

ArticleYear
Nitrous oxide and perioperative outcomes.
    Journal of anesthesia, 2014, Volume: 28, Issue:3

    Topics: Analgesics, Non-Narcotic; Anesthetics, Inhalation; Cardiovascular Diseases; Humans; Lung Diseases; N

2014
[New non-invasive assessments of inflammation process in asthma].
    Duodecim; laaketieteellinen aikakauskirja, 2003, Volume: 119, Issue:11

    Topics: Asthma; Biomarkers; Breath Tests; Diagnosis, Differential; Eosinophils; Humans; Lung Diseases; Nitro

2003
[Pulmonary toxicity of free radicals of oxygen].
    Revue francaise des maladies respiratoires, 1983, Volume: 11, Issue:1

    Topics: Animals; Bleomycin; Cadmium; Cadmium Chloride; Chemical Phenomena; Chemistry; Free Radicals; Humans;

1983
Oxidant gases.
    Environmental health perspectives, 1984, Volume: 55

    Topics: Animals; Bronchi; Epithelium; Gases; Humans; Lung; Lung Diseases; Nitrous Oxide; Nutritional Physiol

1984
The biology of nitrogen oxides in the airways.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:2 Pt 1

    Topics: Amino Acid Oxidoreductases; Animals; Humans; Lung; Lung Diseases; Nitric Oxide; Nitric Oxide Synthas

1994
The biology of nitrogen oxides in the airways.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:2 Pt 1

    Topics: Amino Acid Oxidoreductases; Animals; Humans; Lung; Lung Diseases; Nitric Oxide; Nitric Oxide Synthas

1994
The biology of nitrogen oxides in the airways.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:2 Pt 1

    Topics: Amino Acid Oxidoreductases; Animals; Humans; Lung; Lung Diseases; Nitric Oxide; Nitric Oxide Synthas

1994
The biology of nitrogen oxides in the airways.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:2 Pt 1

    Topics: Amino Acid Oxidoreductases; Animals; Humans; Lung; Lung Diseases; Nitric Oxide; Nitric Oxide Synthas

1994
[Toxic and drug-induced lesions of the pulmonary parenchyma].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1992, May-05, Volume: 81, Issue:19

    Topics: Alveolitis, Extrinsic Allergic; Antineoplastic Agents; Herbicides; Humans; Lung Diseases; Nitrous Ox

1992
Acute nitrous oxide intoxication: clinical symptoms, pathophysiology and treatment.
    The Netherlands journal of medicine, 1990, Volume: 37, Issue:3-4

    Topics: Acute Disease; Humans; Lung Diseases; Nitrous Oxide

1990
The response of the lung to foreign compounds that produce free radicals.
    Annual review of physiology, 1986, Volume: 48

    Topics: Air Pollutants; Animals; Bleomycin; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; DNA; Dogs;

1986
Physiological aspects of one-lung (endobronchial) anesthesia.
    International anesthesiology clinics, 1972,Winter, Volume: 10, Issue:4

    Topics: Aged; Anesthesia, Inhalation; Bronchi; Carbon Dioxide; Carcinoma, Bronchogenic; Cardiac Output; Fema

1972

Trials

2 trials available for nitrous oxide and Disease, Pulmonary

ArticleYear
Use of midazolam ('Dormicum') and flumazenil ('Anexate') in paediatric bronchology.
    Current medical research and opinion, 1992, Volume: 12, Issue:9

    Topics: Anesthesia; Atropine; Bronchoscopy; Child, Preschool; Chronic Disease; Drug Administration Schedule;

1992
Postoperative pulmonary complications using dry and humidified anaesthetic gases.
    British journal of anaesthesia, 1973, Volume: 45, Issue:4

    Topics: Abdomen; Aged; Anesthesia, Inhalation; Body Temperature; Carbon Dioxide; Clinical Trials as Topic; F

1973

Other Studies

28 other studies available for nitrous oxide and Disease, Pulmonary

ArticleYear
1-1-12 one-step wash-in scheme for desflurane low flow anesthesia: performance without nitrous oxide.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Adolescent; Adult; Anesthesia, General; Blood Pressure; Desflurane; Female; Heart Diseases; Heart Ra

2015
Nitrogen dioxide pneumonia: a recently discovered malady in silo-fillers.
    GP, 1957, Volume: 16, Issue:5

    Topics: Humans; Lung Diseases; Nitrogen Dioxide; Nitrous Oxide; Occupational Diseases; Pneumonia; Silo Fille

1957
Silo-fillers disease; report of a case.
    The New England journal of medicine, 1958, Mar-13, Volume: 258, Issue:11

    Topics: Humans; Lung Diseases; Medical Records; Nitrous Oxide; Occupational Diseases

1958
Chronic pulmonary insufficiency secondary to silo-filler's disease.
    The American journal of medicine, 1958, Volume: 24, Issue:3

    Topics: Disease; Endocardium; Humans; Lung Diseases; Medical Records; Nitrous Oxide; Occupational Diseases;

1958
Chronic silo filler's disease.
    Connecticut state medical journal, 1958, Volume: 22, Issue:7

    Topics: Humans; Lung Diseases; Medical Records; Nitrous Oxide; Occupational Diseases; Silo Filler's Disease

1958
Anesthesia and obstructive lung disorders.
    Clinical anesthesia, 1967, Volume: 1

    Topics: Adult; Aged; Anesthesia; Anesthesia, General; Asthma; Bronchial Spasm; Child, Preschool; Cyclopropan

1967
Nitrous oxide - are there any real contraindications?
    Quintessence international, dental digest, 1983, Volume: 14, Issue:2

    Topics: Anesthesia, Dental; Anesthesia, Inhalation; Heart Diseases; Humans; Lung Diseases; Mental Disorders;

1983
Homemade nitrous oxide: no laughing matter.
    Annals of internal medicine, 1982, Volume: 96, Issue:3

    Topics: Adult; Drug Contamination; Humans; Lung Diseases; Male; Nitrogen Dioxide; Nitrous Oxide; Substance-R

1982
Evaluating the role of inducible nitric oxide synthase using a novel and selective inducible nitric oxide synthase inhibitor in septic lung injury produced by cecal ligation and puncture.
    American journal of respiratory and critical care medicine, 2000, Volume: 162, Issue:2 Pt 1

    Topics: Amidines; Animals; Cecum; Enzyme Inhibitors; Heterocyclic Compounds, 2-Ring; Isoenzymes; Ligation; L

2000
Asymptomatic diaphragmatic defect--a post-operative problem.
    Canadian Anaesthetists' Society journal, 1978, Volume: 25, Issue:2

    Topics: Anesthesia, General; Diaphragm; Female; Humans; Lung Diseases; Maxilla; Middle Aged; Nitrous Oxide;

1978
Quantitation of damage to the alveolar epithelium by means of type 2 cell proliferation.
    The American review of respiratory disease, 1978, Volume: 118, Issue:4

    Topics: Animals; Cell Division; Environmental Exposure; Epithelium; Lung Diseases; Nitrous Oxide; Pulmonary

1978
Diagnostic and therapeutic regime for reducing mortality after resection of tumours in the head and neck.
    Journal of maxillofacial surgery, 1975, Volume: 3, Issue:1

    Topics: Barbiturates; Blood Transfusion; Bronchopneumonia; Embolism; Halothane; Head; Head and Neck Neoplasm

1975
Measurement of pulmonary capillary blood flow by a nitrous oxide rebreathing technique.
    Acta anaesthesiologica Scandinavica, 1986, Volume: 30, Issue:7

    Topics: Anesthesia, Closed-Circuit; Anesthesia, General; Animals; Capillaries; Cardiac Output; Female; Lung

1986
[Clinico-physiological substantiation of using various methods of anesthesia in operations on the lungs in patients with chronic respiratory insufficiency].
    Vestnik khirurgii imeni I. I. Grekova, 1985, Volume: 134, Issue:6

    Topics: Anesthesia, General; Chronic Disease; Ether; Fentanyl; Halothane; Hemodynamics; Humans; Lung Disease

1985
[Decurarization with calcium pantothenate after operations on pulmonary patients with bronchial asthma].
    Vestnik khirurgii imeni I. I. Grekova, 1974, Volume: 113, Issue:8

    Topics: Adult; Asthma; Atropine; Calcium; Drug Therapy, Combination; Electrocardiography; Female; Halothane;

1974
The use of nitrous oxide during ventilation with the open bronchoscope.
    Anesthesiology, 1973, Volume: 39, Issue:5

    Topics: Adult; Aged; Bronchoscopes; Bronchoscopy; Humans; Lung Diseases; Methods; Middle Aged; Nitrous Oxide

1973
ASOS anesthesia morbidity and mortality survey.
    Journal of oral surgery (American Dental Association : 1965), 1974, Volume: 32, Issue:10

    Topics: Administration, Oral; Anesthesia, Dental; Anesthesia, General; Anesthesia, Local; Anesthesiology; Ce

1974
Measurement of coronary sinus blood flow by dye dilution technique in man.
    The Journal of laboratory and clinical medicine, 1972, Volume: 79, Issue:1

    Topics: Adolescent; Adult; Animals; Aorta; Blood Pressure; Body Weight; Bronchiectasis; Cardiac Catheterizat

1972
The effects of general anaesthesia on the surface tension of secretions in the upper airway in patients with and without pulmonary disease.
    Canadian Anaesthetists' Society journal, 1973, Volume: 20, Issue:3

    Topics: Adult; Aged; Anesthesia, General; Bronchi; Halothane; Humans; Lung Diseases; Middle Aged; Narcotics;

1973
[Bronchodilatory effect of mechanical actions on the thorax in children].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 76, Issue:7

    Topics: Adolescent; Airway Resistance; Anesthesia, Inhalation; Bronchi; Child; Child, Preschool; Halothane;

1973
An unusual cause of a high central venous pressure during anaesthesia.
    Anaesthesia, 1966, Volume: 21, Issue:4

    Topics: Adolescent; Anesthesia, Endotracheal; Arm Injuries; Brachiocephalic Veins; Embolism, Air; Halothane;

1966
Sudden hyperpyrexia during general anesthesia.
    Surgery, 1969, Volume: 66, Issue:5

    Topics: Adult; Anesthesia, Inhalation; Brain Diseases; Cerebral Cortex; Edema; Fever; Hemorrhage; Hernia, In

1969
[Bronchoscopy under anesthesia at a district hospital].
    Problemy tuberkuleza, 1970, Volume: 48, Issue:6

    Topics: Adolescent; Adult; Anesthesia; Barbiturates; Bronchoscopy; Child; Female; Humans; Lung Diseases; Mal

1970
The effects of halothane and atropine on total respiratory resistance in anesthetized man.
    Anesthesiology, 1970, Volume: 33, Issue:3

    Topics: Adult; Aged; Airway Resistance; Anesthesia, General; Atropine; Bronchi; Bronchial Spasm; Chronic Dis

1970
Comparison of effects of three anaesthetic techniques on patients with severe pulmonary obstructive disease.
    Canadian Anaesthetists' Society journal, 1971, Volume: 18, Issue:3

    Topics: Anesthesia, Conduction; Anesthesia, Epidural; Blood Gas Analysis; Ethyl Ethers; Humans; Lung Disease

1971
Arterial oxygen tension during nitrous oxide-oxygen-halothane anaesthesia in patients with cardiovascular and pulmonary disease.
    Acta anaesthesiologica Scandinavica, 1967, Volume: 11, Issue:4

    Topics: Acid-Base Equilibrium; Anesthesia, Inhalation; Carbon Dioxide; Cardiovascular Diseases; Halothane; H

1967
[Application of nitrous oxide after surgery as a method of prevention of lung complications].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1966, Oct-17, Volume: 21, Issue:42

    Topics: Humans; Lung Diseases; Nitrous Oxide; Postoperative Complications

1966
Choice of anesthetic technique in patients with acute pulmonary disease.
    JAMA, 1966, Sep-05, Volume: 197, Issue:10

    Topics: Aged; Anesthesia, General; Drainage; Female; Halothane; Humans; Lung Diseases; Nitrous Oxide; Oxygen

1966