Page last updated: 2024-10-19

nitrous oxide and Cough

nitrous oxide has been researched along with Cough in 19 studies

Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.

Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy of continuous administration of 50% nitrous oxide in oxygen for reducing pain during flexible fiberoptic bronchoscopy 32 children aged 3-60 months were randomly assigned to an experimental or a control group."9.08[Bronchial endoscopy under local anesthesia and pain in children. The value of a nitrous oxide-oxygen combination]. ( Dupont, D; Garcia, J; Hayem, C; Roure, P, 1998)
"ET cuffs filled with alkalinized lidocaine prevented the occurrence of high cuff pressures during N2O anesthesia and reduced ET discomfort and postoperative sore throat incidence."5.12Effectiveness and safety of endotracheal tube cuffs filled with air versus filled with alkalinized lidocaine: a randomized clinical trial. ( Braz, JR; Lima, RM; Módolo, NS; Nakamura, G; Navarro, LH; Silva, Fde P, 2007)
"In healthy premedicated children, aged 2 to 6 years, who are undergoing induction of anesthesia with halothane-N2O, 2 mg/kg of lidocaine given 90 seconds prior to laryngoscopy effectively suppresses the cough reflex and increase in IOP secondary to endotracheal intubation and attenuates increases in HR and MAP."5.08Is intravenous lidocaine an effective adjuvant for endotracheal intubation in children undergoing induction of anesthesia with halothane-nitrous oxide? ( Balch, DR; Davidson, PJ; Warner, LO, 1997)
"To evaluate the efficacy of continuous administration of 50% nitrous oxide in oxygen for reducing pain during flexible fiberoptic bronchoscopy 32 children aged 3-60 months were randomly assigned to an experimental or a control group."5.08[Bronchial endoscopy under local anesthesia and pain in children. The value of a nitrous oxide-oxygen combination]. ( Dupont, D; Garcia, J; Hayem, C; Roure, P, 1998)
"Isoflurane was compared with sevoflurane in terms of rapidity, efficacy, safety and acceptability of induction."2.69Single vital capacity inhalational anaesthetic induction in adults--isoflurane vs sevoflurane. ( Lee, TL; Pua, HL; Ti, LK, 1998)
"Sevoflurane patients were less likely to have complications during induction (P < 0."2.68Sevoflurane versus isoflurane: induction and recovery characteristics with single-breath inhaled inductions of anesthesia. ( Conard, PF; Gross, JB; Karsunky, PK; Sloan, MH, 1996)
"The presence of gagging, coughing, laryngospasm and movement was noted and graded."2.67Patient response to laryngeal mask insertion after induction of anaesthesia with propofol or thiopentone. ( Carey, M; Kirby, F; Power, M; Scanlon, P, 1993)
"Moderate-to-severe laryngospasm (49%) and moderate-to-severe coughing (58%) occurred frequently during induction of anesthesia with desflurane; the incidence of these was not altered by premedication."1.28Induction and maintenance characteristics of anesthesia with desflurane and nitrous oxide in infants and children. ( Coté, CJ; Davis, PJ; Dinner, M; Fisher, DM; Hannallah, RS; Liu, LM; McGill, WA; Sarner, J; Welborn, LG; Zwass, MS, 1992)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19905 (26.32)18.7374
1990's8 (42.11)18.2507
2000's4 (21.05)29.6817
2010's1 (5.26)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Armstrong, J1
Jenner, P1
Poulose, S1
Moppett, IK1
Makkar, JK1
Ghai, B1
Bhardwaj, N1
Wig, J1
Bajaj, P1
Nanda, R1
Goyal, PK1
Hohlrieder, M1
Tiefenthaler, W1
Klaus, H1
Gabl, M1
Kavakebi, P1
Keller, C1
Benzer, A1
Navarro, LH1
Braz, JR1
Nakamura, G1
Lima, RM1
Silva, Fde P1
Módolo, NS1
Iwasaki, H1
Namiki, A1
Omote, T1
Scanlon, P1
Carey, M1
Power, M1
Kirby, F1
Sloan, MH1
Conard, PF1
Karsunky, PK1
Gross, JB1
Harling, DW1
Harrison, DA1
Dorman, T1
Barker, I1
Warner, LO1
Balch, DR1
Davidson, PJ1
Garcia, J1
Roure, P1
Hayem, C1
Dupont, D1
Boufflers, E1
Maslowski, D1
Menu, H1
Guermouche, T1
Theeten, G1
Beague, D1
Reyford, H1
Krivosic-Horber, R1
Ti, LK1
Pua, HL1
Lee, TL1
Olympio, MA1
Youngblood, BL1
James, RL1
Tammisto, T1
Mattila, MJ1
Lanning, CF1
Harmel, MH1
Zwass, MS1
Fisher, DM1
Welborn, LG1
Coté, CJ1
Davis, PJ1
Dinner, M1
Hannallah, RS1
Liu, LM1
Sarner, J1
McGill, WA1
Delilkan, AE1
Chandran, S1
Kristoffersen, MB1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Comparative Analysis of Elevated Endotracheal Tube Cuff Pressure Incidence in Elective Laparoscopic Abdominal Surgery: Saline vs. Air Inflation[NCT06089187]60 participants (Actual)Interventional2023-09-27Completed
Reducing Intra-operative Pressure Variations in Paediatric Microcuff Endotracheal Tube Cuffs[NCT03240354]49 participants (Actual)Interventional2018-08-06Completed
Effect of Head Position on Minimum Alveolar Concentration of Endotracheal Intubation(MACEI)of Sevoflurane in Children With Obstructive Airway[NCT03522402]38 participants (Anticipated)Interventional2018-01-01Enrolling by invitation
Can Propofol Reduce Respiratory Adverse Events During Extubation in Children With Tonsillectomy? A Prospective Randomized Controlled Study[NCT05769842]240 participants (Anticipated)Interventional2023-11-01Not yet recruiting
Effect of Two Plasma Concentrations of Remifentanil Through Target Controlled Anesthesia on Frequency and Intensity of Coughing During Extubation: Randomized Controlled Clinical Trial[NCT02711904]Phase 4110 participants (Actual)Interventional2011-01-31Completed
Efficiency of Intravenous Lidocaine to Reduce Coughing and the Hemodynamic Changes Associated to Tracheal Extubation[NCT03731429]Phase 4144 participants (Anticipated)Interventional2019-04-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nitrous oxide and Cough

ArticleYear
Ketamine anesthesia.
    Annual review of medicine, 1975, Volume: 26

    Topics: Anesthesia, General; Animals; Blood Pressure; Bronchial Spasm; Central Nervous System; Central Venou

1975

Trials

13 trials available for nitrous oxide and Cough

ArticleYear
The effect of saline versus air for cuff inflation on the incidence of high intra-cuff pressure in paediatric MicroCuff
    Anaesthesia, 2021, Volume: 76, Issue:11

    Topics: Adolescent; Air; Anesthetics, Inhalation; Child; Child, Preschool; Cough; Female; Humans; Infant; In

2021
The effect of saline versus air for cuff inflation on the incidence of high intra-cuff pressure in paediatric MicroCuff
    Anaesthesia, 2021, Volume: 76, Issue:11

    Topics: Adolescent; Air; Anesthetics, Inhalation; Child; Child, Preschool; Cough; Female; Humans; Infant; In

2021
The effect of saline versus air for cuff inflation on the incidence of high intra-cuff pressure in paediatric MicroCuff
    Anaesthesia, 2021, Volume: 76, Issue:11

    Topics: Adolescent; Air; Anesthetics, Inhalation; Child; Child, Preschool; Cough; Female; Humans; Infant; In

2021
The effect of saline versus air for cuff inflation on the incidence of high intra-cuff pressure in paediatric MicroCuff
    Anaesthesia, 2021, Volume: 76, Issue:11

    Topics: Adolescent; Air; Anesthetics, Inhalation; Child; Child, Preschool; Cough; Female; Humans; Infant; In

2021
Pressure and volume changes of tracheal tube cuff following inflation with various inflating agents during nitrous oxide anesthesia.
    Middle East journal of anaesthesiology, 2004, Volume: 17, Issue:6

    Topics: Air; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Cough; Deglutition Disorde

2004
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effect of total intravenous anaesthesia and balanced anaesthesia on the frequency of coughing during emergence from the anaesthesia.
    British journal of anaesthesia, 2007, Volume: 99, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inh

2007
Effectiveness and safety of endotracheal tube cuffs filled with air versus filled with alkalinized lidocaine: a randomized clinical trial.
    Sao Paulo medical journal = Revista paulista de medicina, 2007, Nov-01, Volume: 125, Issue:6

    Topics: Administration, Inhalation; Adolescent; Adult; Anesthesia, Inhalation; Anesthetics, Local; Cough; Fe

2007
Patient response to laryngeal mask insertion after induction of anaesthesia with propofol or thiopentone.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:9

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Cough; Extremities; Female; Gagging; Head; H

1993
Sevoflurane versus isoflurane: induction and recovery characteristics with single-breath inhaled inductions of anesthesia.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:3

    Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Inh

1996
A comparison of thiopentone-isoflurane anaesthesia vs propofol infusion in children having repeat minor haematological procedures.
    Paediatric anaesthesia, 1997, Volume: 7, Issue:1

    Topics: Acute Disease; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Biopsy, Nee

1997
Is intravenous lidocaine an effective adjuvant for endotracheal intubation in children undergoing induction of anesthesia with halothane-nitrous oxide?
    Journal of clinical anesthesia, 1997, Volume: 9, Issue:4

    Topics: Adjuvants, Anesthesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Child; C

1997
[Bronchial endoscopy under local anesthesia and pain in children. The value of a nitrous oxide-oxygen combination].
    Revue des maladies respiratoires, 1998, Volume: 15, Issue:2

    Topics: Adjuvants, Anesthesia; Administration, Rectal; Anesthesia, Local; Anesthetics, Inhalation; Anestheti

1998
Single vital capacity inhalational anaesthetic induction in adults--isoflurane vs sevoflurane.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:10

    Topics: Adolescent; Adult; Anesthesia, Closed-Circuit; Anesthesia, Inhalation; Anesthetics, Inhalation; Coug

1998
Emergence from anesthesia in the prone versus supine position in patients undergoing lumbar surgery.
    Anesthesiology, 2000, Volume: 93, Issue:4

    Topics: Androstanols; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Anestheti

2000
Antitussive respiratory depressant effects of dextromoramide, fentanyl, morphine, pentazocine, and pethidine during the N2O-O2 anaesthesia in man.
    Annals of clinical research, 1977, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Antitussive Agents; Atropi

1977
Cataract extractions without tracheal intubation.
    Canadian Anaesthetists' Society journal, 1974, Volume: 21, Issue:4

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Atropine; Carbon Dioxide; Cataract Ext

1974

Other Studies

5 other studies available for nitrous oxide and Cough

ArticleYear
Minimum alveolar concentration of desflurane with fentanyl for laryngeal mask airway removal in anesthetized children.
    Paediatric anaesthesia, 2012, Volume: 22, Issue:4

    Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Child, Preschool; Cou

2012
[Studies on the vital responses caused by coughing under endotracheal anesthesia. --Part 2. Changes in intra-abdominal, intrathoracic, cerebrospinal fluid and central venous pressures and circulatory responses caused by coughing under various neuromuscula
    Masui. The Japanese journal of anesthesiology, 1982, Volume: 31, Issue:9

    Topics: Adult; Aged; Anesthesia, Endotracheal; Central Venous Pressure; Cough; Female; Hemodynamics; Humans;

1982
-The clinical use of the cuffed oropharyngeal airway (COPA)-.
    Annales francaises d'anesthesie et de reanimation, 1998, Volume: 17, Issue:3

    Topics: Adult; Aged; Alfentanil; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous;

1998
Induction and maintenance characteristics of anesthesia with desflurane and nitrous oxide in infants and children.
    Anesthesiology, 1992, Volume: 76, Issue:3

    Topics: Anesthesia, Inhalation; Atropine; Child; Child, Preschool; Cough; Desflurane; Diazepam; Halothane; H

1992
[Entonox--ready-mixed 02-N20].
    Nordisk medicin, 1968, Oct-10, Volume: 80, Issue:41

    Topics: Analgesics; Anesthesia, Dental; Anesthesia, Obstetrical; Cough; Humans; Nitrous Oxide; Oxygen; Physi

1968