nitrous oxide has been researched along with Chemical Dependence in 182 studies
Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nitrous oxide myelopathy is rare in children." | 7.80 | Nitrous oxide myelopathy in a pediatric patient. ( Hu, MH; Huang, GS; Hung, PC; Wu, CT, 2014) |
| "The authors describe a patient who presented with acute tetraparesis and a proposed acute traumatic spinal cord injury that was the result of nitrous oxide myelopathy." | 7.78 | Nitrous oxide myelopathy posing as spinal cord injury. ( Dalyai, R; Flanders, AE; Ghobrial, GM; Harrop, J, 2012) |
| "Inhaled nitrous oxide can reveal asymptomatic pneumothorax by worsening it." | 7.74 | [Pneumothorax following recreational inhalation of nitrous oxide]. ( Boutemy, M; Garbaz, L; Jounieaux, V; Mispelaere, D, 2007) |
| "A 23 year old man presented with a severe posterior column myelopathy related to prolonged nitrous oxide abuse obtained from whipped cream bulbs." | 7.70 | Nitrous oxide myelopathy in an abuser of whipped cream bulbs. ( Butzkueven, H; King, JO, 2000) |
| "N2O inactivates vitamin B12, leading to vitamin B12 deficiency and subsequent to hyperhomocysteinemia, which is associated with the formation of fibrinolysis-resistant blood thrombi." | 5.62 | [Thromboembolisms due to recreational use of nitrous oxide]. ( de Metz, J; Fokkema, TMM; Kuipers, RS; Oomens, T; Riezebos, RK; van den Bogaard, B; van Nieuwenhuizen, RC, 2021) |
| "A 27-year-old woman presented with confusion, agitation and fever." | 5.51 | Encephalitis secondary to nitrous oxide and vitamin B ( Dedicoat, MJ; Hughes, G; Moran, E, 2019) |
| "She exhibited dystonia in four limbs with athetoid movement in fingers and toes, worsened by eye closure." | 5.43 | Nitrous Oxide-induced Subacute Combined Degeneration Presenting with Dystonia and Pseudoathetosis: A Case Report. ( Chen, HJ; Huang, CS, 2016) |
| "Nitrous oxide (N2O) abuse has been associated with myeloneuropathy, but significant mental status changes rarely have been described." | 5.27 | Subacute toxic delirium following nitrous oxide abuse. ( Coyle, PK; Sterman, AB, 1983) |
| "MEOPA (equimolar mixture of oxygen and nitrous oxide) is used for its analgesic and anxiolytic properties in order to obtain conscious sedation of the patient when performing painful care." | 3.85 | [MEOPA use practices in a university hospital: Which conformity?] ( Cosset, C; Jolliet, P; Joyau, C; Kuhn, E; Le Pelletier, A; Nizard, J; Paille, C; Veyrac, G; Victorri-Vigneau, C, 2017) |
| "We present a case of non-immune haemolytic anaemia with leukopenia and acute severe neurological impairments, as a result of severe vitamin B12 deficiency due to recreational use of nitrous oxide." | 3.85 | Is nitrous oxide really that joyful? ( Ertekin, E; Glijn, NHP; Grimbergen, YAM; Libourel, EJ; van Burg, PLM; van der Linde, D, 2017) |
| "Nitrous oxide myelopathy is rare in children." | 3.80 | Nitrous oxide myelopathy in a pediatric patient. ( Hu, MH; Huang, GS; Hung, PC; Wu, CT, 2014) |
| "The authors describe a patient who presented with acute tetraparesis and a proposed acute traumatic spinal cord injury that was the result of nitrous oxide myelopathy." | 3.78 | Nitrous oxide myelopathy posing as spinal cord injury. ( Dalyai, R; Flanders, AE; Ghobrial, GM; Harrop, J, 2012) |
| "The objective of this study was determine if core temperature (T (core)), a common measure in drug research, can mask the variability both in underlying pharmacological effects and physiological counter-responses during an initial administration of the hypothermia-promoting drug, nitrous oxide (N(2)O)." | 3.74 | Direct evidence for systems-level modulation of initial drug (in)sensitivity in rats. ( Butt, S; Kaiyala, KJ; Ramsay, DS, 2007) |
| "Inhaled nitrous oxide can reveal asymptomatic pneumothorax by worsening it." | 3.74 | [Pneumothorax following recreational inhalation of nitrous oxide]. ( Boutemy, M; Garbaz, L; Jounieaux, V; Mispelaere, D, 2007) |
| "A 23 year old man presented with a severe posterior column myelopathy related to prolonged nitrous oxide abuse obtained from whipped cream bulbs." | 3.70 | Nitrous oxide myelopathy in an abuser of whipped cream bulbs. ( Butzkueven, H; King, JO, 2000) |
| "Nitrous oxide has become over the last few years a public health problem in many countries." | 1.91 | Nitrous oxide: a unique official French addictovigilance national survey. ( Aquizerate, A; Daveluy, A; Duval, M; Gérardin, M; Guerlais, M; Istvan, M; Laforgue, EJ; Lionnet, A; Victorri-Vigneau, C, 2023) |
| "Regular alcohol use, binge drinking, and current tobacco use were higher in PSI users than in non-users." | 1.72 | Psychoactive substance use among students: A cross-sectional analysis. ( Daveluy, A; Fatseas, M; Fourrier-Réglat, A; Letinier, L; Mathieu, C; Pereira, E; Perino, J; Perret, G; Peyré, A; Pollet, C; Tournier, M; Tzourio, C, 2022) |
| "We report four cases of subacute combined degeneration induced by recreational nitrous oxide abuse despite self-administered vitamin B12 supplementation." | 1.72 | Nitrous oxide abuse induced subacute combined degeneration despite patient initiated B12 supplementation. ( Horowitz, BZ; Temple, C, 2022) |
| "All cases of neurological disorders related to nitrous oxide recreational use reported to the Hauts-de-France addictovigilance center between January 2019 and August 2020 were selected." | 1.72 | Myeloneuropathy induced by recreational nitrous oxide use with variable exposure levels. ( Bordet, R; Caous, AS; Carton, L; Deheul, S; Gautier, S; Karam, A; Kuchcinski, G; Largeau, B; Potey, C; Tard, C, 2022) |
| "Multiple illicit substance users were more likely to use methamphetamine (p = 0." | 1.72 | Survey of substance use among adolescent drug offenders referred from juvenile courts in Taiwan: Clinical epidemiology of single versus multiple illicit substance use. ( Chen, LY; Chen, MH; Chen, YH; Wei, HT, 2022) |
| "N2O inactivates vitamin B12, leading to vitamin B12 deficiency and subsequent to hyperhomocysteinemia, which is associated with the formation of fibrinolysis-resistant blood thrombi." | 1.62 | [Thromboembolisms due to recreational use of nitrous oxide]. ( de Metz, J; Fokkema, TMM; Kuipers, RS; Oomens, T; Riezebos, RK; van den Bogaard, B; van Nieuwenhuizen, RC, 2021) |
| "The taboo culture surrounding substance use-mistrust, shame and macho culture-frustrates timely medical/psychological treatment of Moroccan-Dutch problematic nitrous oxide users." | 1.62 | Problematic Use of Nitrous Oxide by Young Moroccan-Dutch Adults. ( Nabben, T; van Amsterdam, J; Weijs, J, 2021) |
| "Nitrous oxide has long been used recreationally for its ability to induce euphoria and other deliriant effects." | 1.56 | Nitrous Oxide Inhalant Use Disorder Preceding Symptoms Concerning for Primary Psychotic Illness. ( Farahmand, P; Roberts, D; Wolkin, A, 2020) |
| "Nitrous oxide has become a popular inhalant as abused substance by young Chinese people in recent years." | 1.56 | Isolated cortical vein thrombosis after nitrous oxide use in a young woman: a case report. ( Bu, B; Liu, M; Zhang, J, 2020) |
| "A 27-year-old woman presented with confusion, agitation and fever." | 1.51 | Encephalitis secondary to nitrous oxide and vitamin B ( Dedicoat, MJ; Hughes, G; Moran, E, 2019) |
| " Accidental injury is associated with the highest number of 'hits' per session, suggesting a dose-response relationship." | 1.43 | Up: The rise of nitrous oxide abuse. An international survey of contemporary nitrous oxide use. ( Devaney, M; Ferris, J; Kaar, SJ; Ramsey, J; Waldron, J; Winstock, AR, 2016) |
| "She exhibited dystonia in four limbs with athetoid movement in fingers and toes, worsened by eye closure." | 1.43 | Nitrous Oxide-induced Subacute Combined Degeneration Presenting with Dystonia and Pseudoathetosis: A Case Report. ( Chen, HJ; Huang, CS, 2016) |
| "A case of subacute combined degeneration (SCD) of the spinal cord manifesting as severe ataxia and urinary retention in a patient with a history of heavy nitrous oxide abuse and self-supplementation with cyanocobalamin is reported." | 1.42 | Subacute combined degeneration of the spinal cord in a patient abusing nitrous oxide and self-medicating with cyanocobalamin. ( Ambrose, TM; Neuburger, KJ; Oettinger, GR; Pugliese, RS; Slagle, EJ, 2015) |
| "This case discusses subacute combined degeneration of the spinal cord on a background of N2O abuse." | 1.39 | Subacute combined degeneration of the spinal cord following recreational nitrous oxide use. ( Cheng, HM; Hernstadt, D; Park, JH, 2013) |
| "The annual death rate from drug abuse for teenagers increased from 1." | 1.37 | Trends and pattern of drug abuse deaths in Maryland teenagers. ( Fowler, DR; Levine, B; Li, G; Li, L; Zhang, X; Zielke, HR, 2011) |
| "Nitrous oxide is a common adjuvant to anaesthesia in the ED but it not often thought of as a drug of abuse." | 1.36 | Peripheral neuropathy following nitrous oxide abuse. ( Richardson, PG, 2010) |
| "Nitrous oxide toxicity has been reported in medical and dental professions and a few cases of myeloneuropathy due to induced vitamin B12 deficiency have been reported." | 1.30 | Myeloneuropathy from whipped cream bulbs presenting as conversion disorder. ( Brett, A, 1997) |
| "Nitrous oxide is a popular inhalation anesthetic-analgesic agent." | 1.29 | Accidental death by nitrous oxide inhalation. ( Rozin, L; Wahba, WW; Winek, CL, 1995) |
| "Chemical dependence is a devastating disease that, unless some form of intervention and treatment takes place, will ultimately destroy a person's life." | 1.29 | The Texas Dental Peer Assistance Program and the impaired dental professional. ( Jessee, SA, 1993) |
| "All presented with paresthesias, weakness, and Lhermitte's phenomena, and exhibited signs of sensorimotor polyneuropathy, ataxia, and arreflexia." | 1.28 | Reversible myeloneuropathy of nitrous oxide abuse: serial electrophysiological studies. ( Beresford, HR; Vishnubhakat, SM, 1991) |
| "Nitrous oxide (N2O) abuse has been associated with myeloneuropathy, but significant mental status changes rarely have been described." | 1.27 | Subacute toxic delirium following nitrous oxide abuse. ( Coyle, PK; Sterman, AB, 1983) |
| "The severity and duration of these convulsions were related to the nitrous oxide concentration and duration of exposure." | 1.26 | Physical dependence on nitrous oxide in mice: resemblance to alcohol but not to opiate withdrawal. ( Cervenko, FW; Jhamandas, KH; Milne, B, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 54 (29.67) | 18.7374 |
| 1990's | 31 (17.03) | 18.2507 |
| 2000's | 29 (15.93) | 29.6817 |
| 2010's | 36 (19.78) | 24.3611 |
| 2020's | 32 (17.58) | 2.80 |
| Authors | Studies |
|---|---|
| Redmond, J | 1 |
| Cruse, B | 1 |
| Kiers, L | 1 |
| van Riel, AJHP | 2 |
| Hunault, CC | 1 |
| van den Hengel-Koot, IS | 2 |
| Nugteren-van Lonkhuyzen, JJ | 2 |
| de Lange, DW | 2 |
| Hondebrink, L | 2 |
| Perino, J | 1 |
| Tournier, M | 1 |
| Mathieu, C | 1 |
| Letinier, L | 1 |
| Peyré, A | 1 |
| Perret, G | 1 |
| Pereira, E | 1 |
| Fourrier-Réglat, A | 1 |
| Pollet, C | 1 |
| Fatseas, M | 1 |
| Tzourio, C | 1 |
| Daveluy, A | 2 |
| Temple, C | 1 |
| Horowitz, BZ | 1 |
| Huizink, AC | 1 |
| Largeau, B | 1 |
| Karam, A | 1 |
| Potey, C | 1 |
| Caous, AS | 1 |
| Tard, C | 2 |
| Carton, L | 2 |
| Kuchcinski, G | 1 |
| Gautier, S | 1 |
| Deheul, S | 2 |
| Bordet, R | 1 |
| Chen, YH | 1 |
| Chen, MH | 1 |
| Wei, HT | 1 |
| Chen, LY | 1 |
| Inquimbert, C | 1 |
| Maitre, Y | 1 |
| Moulis, E | 1 |
| Gremillet, V | 1 |
| Tramini, P | 1 |
| Valcarcel, J | 1 |
| Carayon, D | 1 |
| Ng, GJ | 1 |
| Chiew, YR | 1 |
| Canali, A | 1 |
| Rieu, JB | 1 |
| MacLean, SJ | 1 |
| Riddell, O | 1 |
| Herold, MD | 1 |
| Frank, VA | 1 |
| Sumnall, H | 1 |
| Grzych, G | 1 |
| Gernez, E | 1 |
| Davion, JB | 1 |
| Dobbelaere, D | 1 |
| Kim, I | 1 |
| Guichard, JC | 1 |
| Girot, M | 1 |
| Humbert, L | 1 |
| Bennis, A | 1 |
| Joncquel, M | 1 |
| Chieux, V | 1 |
| Joly, A | 1 |
| Nasserdine, P | 1 |
| Trillot, N | 1 |
| Douillard, C | 1 |
| Pigny, P | 1 |
| Er, C | 1 |
| Breen, K | 1 |
| Cohen, AT | 1 |
| van der Ben, L | 1 |
| Guerlais, M | 1 |
| Aquizerate, A | 1 |
| Lionnet, A | 1 |
| Duval, M | 1 |
| Gérardin, M | 2 |
| Istvan, M | 1 |
| Laforgue, EJ | 1 |
| Victorri-Vigneau, C | 4 |
| Mair, D | 1 |
| Paris, A | 1 |
| Zaloum, SA | 1 |
| White, LM | 1 |
| Dodd, KC | 1 |
| Englezou, C | 1 |
| Patel, F | 1 |
| Abualnaja, S | 1 |
| Lilleker, JB | 1 |
| Gosal, D | 1 |
| Hayton, T | 1 |
| Liang, D | 1 |
| Allroggen, H | 1 |
| Pucci, M | 1 |
| Keddie, S | 2 |
| Noyce, AJ | 2 |
| Riccò, M | 1 |
| Ferraro, P | 1 |
| Corrado, S | 1 |
| Bottazzoli, M | 1 |
| Marchesi, F | 1 |
| Wekim, R | 1 |
| Lindeman, E | 1 |
| Nordmark Grass, J | 1 |
| Bång Arhammar, J | 1 |
| Fang, X | 1 |
| Li, W | 1 |
| Gao, H | 1 |
| Ma, Y | 1 |
| Dong, X | 2 |
| Zheng, D | 2 |
| Bethmont, A | 1 |
| Harper, CE | 1 |
| Chan, BS | 1 |
| Dawson, AH | 1 |
| McAnulty, J | 1 |
| Hughes, G | 1 |
| Moran, E | 1 |
| Dedicoat, MJ | 1 |
| Roberts, D | 1 |
| Farahmand, P | 1 |
| Wolkin, A | 1 |
| Liu, M | 1 |
| Zhang, J | 1 |
| Bu, B | 1 |
| Lewis, B | 1 |
| Nelson, G | 1 |
| Vu, T | 1 |
| Judge, B | 1 |
| van den Toren, SJ | 1 |
| van Grieken, A | 1 |
| Raat, H | 1 |
| Lai, Y | 1 |
| Cheng, J | 1 |
| Yang, Z | 1 |
| Xiang, Y | 1 |
| Li, L | 2 |
| Ma, X | 1 |
| Li, S | 1 |
| Xue, Y | 1 |
| Yan, P | 1 |
| Chen, M | 1 |
| Wu, J | 1 |
| Oomens, T | 1 |
| Fokkema, TMM | 1 |
| van den Bogaard, B | 1 |
| de Metz, J | 1 |
| van Nieuwenhuizen, RC | 2 |
| Riezebos, RK | 1 |
| Kuipers, RS | 1 |
| Nabben, T | 2 |
| Weijs, J | 1 |
| van Amsterdam, J | 2 |
| Li, Y | 1 |
| Zhang, X | 2 |
| Zhao, C | 1 |
| Dang, XT | 1 |
| Nguyen, TX | 1 |
| Nguyen, TTH | 1 |
| Ha, HT | 1 |
| Vollenbrock, SE | 1 |
| Fokkema, TM | 1 |
| Leijdekkers, VJ | 1 |
| Vahl, AC | 1 |
| Konings, R | 1 |
| Paulus, MC | 1 |
| Wijnhoven, AM | 1 |
| Maessen, GC | 1 |
| Blankensteijn, SR | 1 |
| van der Heyden, MAG | 1 |
| Walker, S | 1 |
| Marshall, J | 1 |
| Ginsberg, L | 1 |
| Paille, C | 1 |
| Joyau, C | 1 |
| Veyrac, G | 1 |
| Cosset, C | 1 |
| Le Pelletier, A | 1 |
| Jolliet, P | 3 |
| Nizard, J | 1 |
| Kuhn, E | 1 |
| Lin, AN | 1 |
| Bause, GS | 1 |
| Glijn, NHP | 1 |
| van der Linde, D | 1 |
| Ertekin, E | 1 |
| van Burg, PLM | 1 |
| Grimbergen, YAM | 1 |
| Libourel, EJ | 1 |
| Hew, A | 1 |
| Lai, E | 1 |
| Radford, E | 1 |
| Adams, A | 1 |
| Kelso, ARC | 1 |
| Turner, B | 1 |
| Schmierer, K | 1 |
| Gnanapavan, S | 1 |
| Malaspina, A | 1 |
| Giovannoni, G | 1 |
| Basnett, I | 2 |
| Antonucci, MU | 1 |
| Ba, F | 1 |
| Wang, R | 1 |
| Acharya, A | 1 |
| Gutteridge, C | 1 |
| Noyce, A | 1 |
| Lan, SY | 1 |
| Kuo, CY | 1 |
| Chou, CC | 1 |
| Kong, SS | 1 |
| Hung, PC | 2 |
| Tsai, HY | 1 |
| Chen, YC | 1 |
| Lin, JJ | 1 |
| Chou, IJ | 1 |
| Lin, KL | 1 |
| Fidalgo, M | 1 |
| Prud'homme, T | 1 |
| Allio, A | 1 |
| Bronnec, M | 1 |
| Bulteau, S | 1 |
| Francis, A | 1 |
| Crossley, R | 1 |
| Brady, S | 1 |
| Cheng, HM | 1 |
| Park, JH | 1 |
| Hernstadt, D | 1 |
| Christen, AG | 1 |
| Christen, JA | 1 |
| Cousaert, C | 1 |
| Heylens, G | 1 |
| Audenaert, K | 1 |
| Rheinboldt, M | 1 |
| Harper, D | 1 |
| Parrish, D | 1 |
| Francis, K | 1 |
| Blase, J | 1 |
| Hu, MH | 1 |
| Huang, GS | 1 |
| Wu, CT | 1 |
| Shwe, Y | 1 |
| Scelsa, SN | 1 |
| Ramsay, DS | 3 |
| Al-Noori, S | 1 |
| Shao, J | 1 |
| Leroux, BG | 1 |
| Woods, SC | 1 |
| Kaiyala, KJ | 3 |
| Chin, J | 1 |
| Forzani, B | 1 |
| Chowdhury, N | 1 |
| Lombardo, S | 1 |
| Rizzo, JR | 1 |
| Ragucci, M | 1 |
| Pugliese, RS | 1 |
| Slagle, EJ | 1 |
| Oettinger, GR | 1 |
| Neuburger, KJ | 1 |
| Ambrose, TM | 1 |
| Randhawa, G | 1 |
| Bodenham, A | 1 |
| Duque, MA | 1 |
| Kresak, JL | 1 |
| Falchook, A | 1 |
| Harris, NS | 1 |
| van den Brink, W | 1 |
| Couec, ML | 1 |
| Grall-Bronnec, M | 1 |
| Feuillet, F | 1 |
| Wainstein, L | 1 |
| Rousselet, M | 1 |
| Pinot, ML | 1 |
| Perrouin, F | 1 |
| Bonnot, O | 1 |
| Drouineau, MH | 1 |
| Kaar, SJ | 1 |
| Ferris, J | 1 |
| Waldron, J | 1 |
| Devaney, M | 1 |
| Ramsey, J | 1 |
| Winstock, AR | 1 |
| Garakani, A | 1 |
| Jaffe, RJ | 1 |
| Savla, D | 1 |
| Welch, AK | 1 |
| Protin, CA | 1 |
| Bryson, EO | 1 |
| McDowell, DM | 1 |
| Dubrey, S | 1 |
| Smith, R | 1 |
| Chen, HJ | 1 |
| Huang, CS | 1 |
| Kangas, BD | 1 |
| Walker, DJ | 3 |
| Zacny, JP | 5 |
| Derus, LM | 1 |
| Mortelmans, LJ | 1 |
| Luc, MJ | 1 |
| Herrijgers, J | 1 |
| Jan, H | 1 |
| Richardson, PG | 1 |
| Garland, EL | 1 |
| Howard, MO | 1 |
| Perron, BE | 1 |
| Hathout, L | 1 |
| El-Saden, S | 1 |
| Levine, B | 1 |
| Li, G | 1 |
| Zielke, HR | 1 |
| Fowler, DR | 1 |
| Probasco, JC | 1 |
| Felling, RJ | 1 |
| Carson, JT | 1 |
| Dorsey, ER | 1 |
| Niessen, TM | 1 |
| Ghobrial, GM | 1 |
| Dalyai, R | 1 |
| Flanders, AE | 1 |
| Harrop, J | 1 |
| Ng, J | 1 |
| O'Grady, G | 1 |
| Pettit, T | 1 |
| Frith, R | 1 |
| Malamed, SF | 1 |
| Clark, MS | 1 |
| DANTO, BL | 1 |
| Miller, MA | 1 |
| Martinez, V | 1 |
| McCarthy, R | 1 |
| Patel, MM | 1 |
| Diamond, AL | 1 |
| Diamond, R | 1 |
| Freedman, SM | 1 |
| Thomas, FP | 1 |
| Seidberg, BH | 1 |
| Sullivan, TH | 1 |
| Abanades, S | 1 |
| Peiró, AM | 1 |
| Farré, M | 1 |
| Beckman, NJ | 1 |
| Waters, MF | 1 |
| Kang, GA | 1 |
| Mazziotta, JC | 1 |
| DeGiorgio, CM | 1 |
| Barrueto, F | 1 |
| Long, H | 1 |
| Nelson, LS | 1 |
| Osterhoudt, KC | 1 |
| Gillman, MA | 4 |
| Shulman, RM | 1 |
| Geraghty, TJ | 1 |
| Tadros, M | 1 |
| Butt, S | 2 |
| Blanton, A | 1 |
| Lin, CY | 1 |
| Guo, WY | 1 |
| Chen, SP | 1 |
| Chen, JT | 1 |
| Kao, KP | 1 |
| Wu, ZA | 1 |
| Liao, KK | 1 |
| Garbaz, L | 1 |
| Mispelaere, D | 1 |
| Boutemy, M | 1 |
| Jounieaux, V | 1 |
| Cartner, M | 1 |
| Sinnott, M | 1 |
| Silburn, P | 1 |
| Dillon, JB | 1 |
| Nevins, MA | 1 |
| Blanco, G | 1 |
| Peters, HA | 1 |
| Lunsford, JM | 1 |
| Wynn, MH | 1 |
| Kwan, WH | 1 |
| Schwartz, RH | 2 |
| Calihan, M | 1 |
| Cady, PA | 1 |
| Aston, R | 1 |
| Torda, TA | 1 |
| Atkinson, RM | 1 |
| Green, JD | 1 |
| Sterman, AB | 1 |
| Coyle, PK | 1 |
| Hirschi, RG | 1 |
| Boyum, R | 1 |
| Gutmann, L | 2 |
| Johnsen, D | 2 |
| Messina, FV | 1 |
| Wynne, JW | 1 |
| LiPuma, JP | 1 |
| Wellman, J | 1 |
| Stern, HP | 1 |
| Milne, B | 1 |
| Cervenko, FW | 1 |
| Jhamandas, KH | 1 |
| Tulunay, FC | 1 |
| Tulunay, M | 1 |
| Akkartal, B | 1 |
| Ayhan, IH | 1 |
| Murray, MJ | 1 |
| Murray, WJ | 1 |
| Garriott, J | 1 |
| Petty, CS | 1 |
| Ficarra, BJ | 1 |
| Lichtor, JL | 2 |
| Coalson, DW | 2 |
| Apfelbaum, JL | 1 |
| Winek, CL | 1 |
| Wahba, WW | 1 |
| Rozin, L | 1 |
| Sandoval, VA | 1 |
| Jessee, SA | 1 |
| Dzoljic, M | 1 |
| Rupreht, J | 1 |
| Erdmann, W | 1 |
| Stijnen, TH | 1 |
| van Briemen, LJ | 1 |
| Dzoljic, MR | 1 |
| Mandel, ID | 1 |
| Dohrn, CS | 1 |
| Uitvlugt, A | 1 |
| de Wit, H | 1 |
| Belknap, JK | 1 |
| Metten, P | 1 |
| Helms, ML | 1 |
| O'Toole, LA | 1 |
| Angeli-Gade, S | 1 |
| Crabbe, JC | 1 |
| Phillips, TJ | 1 |
| Hwang, JC | 1 |
| Himel, HN | 1 |
| Edlich, RF | 1 |
| Lai, NY | 1 |
| Silbert, PL | 1 |
| Erber, WN | 1 |
| Rijks, CJ | 1 |
| Brett, A | 1 |
| Temple, WA | 1 |
| Beasley, DM | 1 |
| Baker, DJ | 1 |
| Jones, HE | 1 |
| Balster, RL | 2 |
| Pema, PJ | 1 |
| Horak, HA | 1 |
| Wyatt, RH | 1 |
| Camarillo, VM | 1 |
| Sadeghi, P | 1 |
| Black, M | 1 |
| Bowen, SE | 1 |
| Daniel, J | 1 |
| McCartney, J | 1 |
| Butzkueven, H | 1 |
| King, JO | 1 |
| Weir, E | 1 |
| Brouette, T | 1 |
| Anton, R | 1 |
| Eichhorn, M | 1 |
| Watson, M | 1 |
| Wurst, F | 1 |
| McKirnan, DJ | 1 |
| Vanable, PA | 1 |
| Ostrow, DG | 1 |
| Hope, B | 1 |
| Iwata, K | 1 |
| O'Keefe, GB | 1 |
| Karanas, A | 1 |
| Smith, RA | 2 |
| Winter, PM | 2 |
| Smith, M | 2 |
| Eger, EI | 2 |
| Layzer, RB | 2 |
| Sahenk, Z | 1 |
| Mendell, JR | 1 |
| Couri, D | 1 |
| Nachtman, J | 1 |
| Fishman, RA | 1 |
| Schafer, JA | 1 |
| Farrell, B | 1 |
| Crosby, TW | 1 |
| Paulson, GW | 1 |
| Tisman, G | 1 |
| Testa, D | 1 |
| Anderson, TA | 1 |
| Bowman, RE | 1 |
| Eadie, MJ | 1 |
| Block, SH | 1 |
| Barber, DN | 1 |
| Wagner, SA | 1 |
| Clark, MA | 1 |
| Wesche, DL | 1 |
| Doedens, DJ | 1 |
| Lloyd, AW | 1 |
| Gowitt, GT | 1 |
| Hanzlick, RL | 1 |
| Lang, JB | 1 |
| Vishnubhakat, SM | 1 |
| Beresford, HR | 1 |
| Jastak, JT | 1 |
| Ingelman-Sundberg, A | 1 |
| Cedarholm, B | 1 |
| Pollard, TG | 1 |
| Yudenfreund-Sujka, SM | 1 |
| Suruda, AJ | 1 |
| McGlothlin, JD | 1 |
| Shimizu, T | 1 |
| Nishimura, Y | 1 |
| Fujishima, Y | 1 |
| Miyajima, H | 1 |
| Honda, N | 1 |
| Salvesen, KA | 1 |
| Jacobson, B | 2 |
| Nyberg, K | 1 |
| Eklund, G | 1 |
| Bygdeman, M | 1 |
| Rydberg, U | 1 |
| Heyer, EJ | 1 |
| Simpson, DM | 1 |
| Bodis-Wollner, I | 1 |
| Diamond, SP | 1 |
| Fraunfelder, FT | 1 |
| Rowbottom, SJ | 1 |
| McHugh, MJ | 1 |
| Stewart, RD | 1 |
| Murdoch, BD | 1 |
| Fleming, JH | 1 |
| Small, SC | 1 |
| Taylor, WJ | 1 |
| Gerula, GR | 1 |
| Lynn, EJ | 1 |
| James, M | 1 |
| Dendy, R | 1 |
| Harris, LA | 1 |
| Walter, RG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PHEDRE Trial Protocol - Observational Study of the Prevalence of Problematic Use of Equimolar Mixture of Oxygen and Nitrous Oxide (EMONO) and Analgesics in the French Sickle-cell Disease Population[NCT02580565] | 1,004 participants (Actual) | Observational | 2015-09-25 | Completed | |||
| Longitudinal Assessment of Neurological Recovery in Patients Following Nitrous Oxide Abuse[NCT05714917] | 100 participants (Anticipated) | Observational | 2023-04-01 | Not yet recruiting | |||
| Epidemiology of Neurological Complications to Nitrous Oxide Poisoning[NCT05329909] | 135 participants (Anticipated) | Observational | 2022-04-10 | Recruiting | |||
| Feasibility and Comfort of a Nasal Demand-Driven Method for Gas Delivery in a Dental Setting[NCT04305990] | 100 participants (Anticipated) | Interventional | 2020-03-31 | Not yet recruiting | |||
| Neurobiología Del Consumo de Substancias Psicoactivas: PET-CT- Inhalables[NCT02188914] | 70 participants (Actual) | Observational | 2014-11-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
23 reviews available for nitrous oxide and Chemical Dependence
| Article | Year |
|---|---|
Trends and associated risks in adolescent substance use: E-cigarette use and nitrous oxide use.
Topics: Adolescent; Electronic Nicotine Delivery Systems; Humans; Nitrous Oxide; Substance-Related Disorders | 2022 |
Recreational Nitrous Oxide Abuse: Prevalence, Neurotoxicity, and Treatment.
Topics: Humans; Illicit Drugs; Neurotoxicity Syndromes; Nitrous Oxide; Recreational Drug Use; Substance-Rela | 2021 |
Does vitamin B12 deficiency explain psychiatric symptoms in recreational nitrous oxide users? A narrative review.
Topics: Administration, Inhalation; Adolescent; Adult; Anesthetics, Inhalation; Dietary Supplements; Female; | 2021 |
Imaging appearance of myelopathy secondary to nitrous oxide abuse: a case report and review of the literature.
Topics: Adult; Cervical Cord; Humans; Magnetic Resonance Imaging; Male; Nitrous Oxide; Quadriplegia; Spinal | 2019 |
Recreational nitrous oxide abuse related subacute combined degeneration of the spinal cord in adolescents - A case series and literature review.
Topics: Adolescent; Adult; Female; Humans; Male; Nitrous Oxide; Outcome Assessment, Health Care; Subacute Co | 2019 |
Nitrous oxide: What do we know about its use disorder potential? Results of the French Monitoring Centre for Addiction network survey and literature review.
Topics: Drug Combinations; France; Humans; Nitrous Oxide; Oxygen; Substance-Related Disorders | 2019 |
Dental education in the prevention and treatment of substance use disorders.
Topics: Alcoholism; Anesthetics, Inhalation; Clinical Competence; Curriculum; Education, Dental; Humanism; H | 2002 |
Laughing gas abuse is no joke. An overview of the implications for psychiatric practice.
Topics: Anesthetics, Inhalation; Humans; Male; Mental Disorders; Nitrous Oxide; Psychiatry; Substance-Relate | 2013 |
Recreational nitrous oxide use: Prevalence and risks.
Topics: Administration, Inhalation; Dose-Response Relationship, Drug; Gases; Humans; Illicit Drugs; Nitrous | 2015 |
Neurologic, psychiatric, and other medical manifestations of nitrous oxide abuse: A systematic review of the case literature.
Topics: Behavior, Addictive; Humans; Neurologic Examination; Nitrous Oxide; Substance-Related Disorders; Vit | 2016 |
Neurologic, psychiatric, and other medical manifestations of nitrous oxide abuse: A systematic review of the case literature.
Topics: Behavior, Addictive; Humans; Neurologic Examination; Nitrous Oxide; Substance-Related Disorders; Vit | 2016 |
Neurologic, psychiatric, and other medical manifestations of nitrous oxide abuse: A systematic review of the case literature.
Topics: Behavior, Addictive; Humans; Neurologic Examination; Nitrous Oxide; Substance-Related Disorders; Vit | 2016 |
Neurologic, psychiatric, and other medical manifestations of nitrous oxide abuse: A systematic review of the case literature.
Topics: Behavior, Addictive; Humans; Neurologic Examination; Nitrous Oxide; Substance-Related Disorders; Vit | 2016 |
Nitrous oxide-induced B₁₂ deficiency myelopathy: Perspectives on the clinical biochemistry of vitamin B₁₂.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cobamides; Cytokines; Folic Acid | 2011 |
[Club drugs: old medicines as new party drugs].
Topics: Designer Drugs; Dextromethorphan; Humans; Hydroxybutyrates; Illicit Drugs; Ketamine; Nitrous Oxide; | 2004 |
A 17-year-old with weakness.
Topics: Administration, Inhalation; Adolescent; Amyl Nitrite; Diagnosis, Differential; Humans; Hydrocarbons; | 2003 |
Occupational risks in dentistry: comforts and concerns.
Topics: Absenteeism; Communicable Diseases; Dentists; Dermatitis, Occupational; Humans; Infection Control; M | 1993 |
Quantitative trait loci (QTL) applications to substances of abuse: physical dependence studies with nitrous oxide and ethanol in BXD mice.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Chromosome Mapping; Genetic Markers; Mice; Mice, I | 1993 |
Inhalant abuse in pregnancy.
Topics: Anesthetics, Inhalation; Animals; Female; Humans; Infant, Newborn; Nitrous Oxide; Occupational Expos | 1998 |
Reflections on volatile substance dependency treatment. Negotiating the boundary between inner and outer reality.
Topics: Administration, Inhalation; Adolescent; Adult; Behavior Therapy; Butanes; Female; Humans; Male; Mode | 1999 |
Clinical review of inhalants.
Topics: Administration, Inhalation; Adolescent; Adolescent Behavior; Analgesics, Non-Narcotic; Child; Humans | 2001 |
Nitrous oxide abuse in perspective.
Topics: Animals; Health Personnel; Humans; Nitrous Oxide; Occupational Diseases; Substance-Related Disorders | 1992 |
Relative addiction potential of major centrally-active drugs and drug classes--inhalants and anesthetics.
Topics: Administration, Inhalation; Anesthetics; Humans; Nitrous Oxide; Psychotropic Drugs; Substance-Relate | 1990 |
[Subacute myeloneuropathy after abuse of nitrous oxide: an electron microscopic study on the peripheral nerve].
Topics: Adult; Demyelinating Diseases; Humans; Male; Microscopy, Electron; Nitrous Oxide; Peripheral Nervous | 1989 |
Nitrous oxide, an opioid addictive agent. Review of the evidence.
Topics: Analgesia; Animals; Drug Tolerance; Humans; Locomotion; Nervous System Diseases; Nitrous Oxide; Opio | 1986 |
The abuse of volatile substances.
Topics: Adolescent; Child; Gasoline; Humans; Hydrocarbons, Halogenated; Nitrites; Nitrous Oxide; Solvents; S | 1987 |
4 trials available for nitrous oxide and Chemical Dependence
| Article | Year |
|---|---|
Choice of nitrous oxide and its subjective effects in light and moderate drinkers.
Topics: Administration, Inhalation; Adult; Alcohol Drinking; Alcoholic Intoxication; Choice Behavior; Cross- | 2008 |
Within-subject comparison of the subjective and psychomotor effects of a gaseous anesthetic and two volatile anesthetics in healthy volunteers.
Topics: Adult; Anesthetics, Inhalation; Arousal; Attention; Conscious Sedation; Cross-Over Studies; Discrimi | 2006 |
Reinforcing effects of extended inhalation of nitrous oxide in humans.
Topics: Administration, Inhalation; Adult; Affect; Arousal; Choice Behavior; Dose-Response Relationship, Dru | 1993 |
Effects of ethanol and nitrous oxide, alone and in combination, on mood, psychomotor performance and pain reports in healthy volunteers.
Topics: Adult; Affect; Cross-Over Studies; Double-Blind Method; Drug Synergism; Ethanol; Female; Humans; Mal | 1998 |
155 other studies available for nitrous oxide and Chemical Dependence
| Article | Year |
|---|---|
Nitrous oxide-induced neurological disorders: an increasing public health concern.
Topics: Adolescent; Humans; Nervous System Diseases; Nitrous Oxide; Public Health; Substance-Related Disorde | 2022 |
Alarming increase in poisonings from recreational nitrous oxide use after a change in EU-legislation, inquiries to the Dutch Poisons Information Center.
Topics: Humans; Illicit Drugs; Information Centers; Nitrous Oxide; Poisons; Substance-Related Disorders | 2022 |
Psychoactive substance use among students: A cross-sectional analysis.
Topics: Adolescent; Adult; Binge Drinking; Cannabis; Cross-Sectional Studies; Ethanol; Female; Humans; Male; | 2022 |
Nitrous oxide abuse induced subacute combined degeneration despite patient initiated B12 supplementation.
Topics: Dietary Supplements; Humans; Illicit Drugs; Nitrous Oxide; Subacute Combined Degeneration; Substance | 2022 |
Myeloneuropathy induced by recreational nitrous oxide use with variable exposure levels.
Topics: Adolescent; Adult; Ataxia; Female; Humans; Male; Nervous System Diseases; Nitrous Oxide; Peripheral | 2022 |
Survey of substance use among adolescent drug offenders referred from juvenile courts in Taiwan: Clinical epidemiology of single versus multiple illicit substance use.
Topics: Adolescent; Criminals; Depressive Disorder, Major; Humans; Illicit Drugs; Ketamine; Methamphetamine; | 2022 |
Recreational Nitrous Oxide Use and Associated Factors among Health Profession Students in France.
Topics: Adult; Female; Health Occupations; Humans; Illicit Drugs; Nitrous Oxide; Students, Health Occupation | 2022 |
Nitrous oxide and cervical myelopathy.
Topics: Cervical Vertebrae; Humans; Magnetic Resonance Imaging; Nitrous Oxide; Spinal Cord Diseases; Substan | 2022 |
Nitrous oxide misuse: Not a laughing matter.
Topics: Humans; Nitrous Oxide; Substance-Related Disorders | 2023 |
Becoming a nitrous oxide user on social media: Learning to maximise pleasures and minimise harms.
Topics: Drug Users; Humans; Nitrous Oxide; Pleasure; Social Media; Substance-Related Disorders | 2022 |
Recreational use of nitrous oxide.
Topics: Humans; Illicit Drugs; Nitrous Oxide; Substance-Related Disorders; Vitamin B 12 | 2022 |
Comparison of biomarker for diagnosis of nitrous oxide abuse: challenge of cobalamin metabolic parameters, a retrospective study.
Topics: Biomarkers; Humans; Methylmalonic Acid; Nitrous Oxide; Retrospective Studies; Substance-Related Diso | 2023 |
Nitrous oxide misuse: a clue not to be missed in young patients with venous thromboembolism.
Topics: Adult; Female; Humans; Male; Nitrous Oxide; Substance-Related Disorders; Venous Thromboembolism; Ven | 2023 |
High Incidence of Signs of Neuropathy and Self-Reported Substance Use Disorder for Nitrous Oxide in Patients Intoxicated with Nitrous Oxide.
Topics: Diagnostic and Statistical Manual of Mental Disorders; Humans; Incidence; Nitrous Oxide; Prospective | 2023 |
Nitrous oxide: a unique official French addictovigilance national survey.
Topics: Cardiovascular Diseases; Female; France; Humans; Nitrous Oxide; Public Health; Substance-Related Dis | 2023 |
Nitrous oxide-induced myeloneuropathy: a case series.
Topics: Humans; Nitrous Oxide; Paresthesia; Spinal Cord Diseases; Substance-Related Disorders | 2023 |
Nitrous Oxide Inhalant Abuse: Preliminary Results from a Cross-Sectional Study on Knowledge, Attitudes, and Practices of Italian Physicians (2023).
Topics: Cross-Sectional Studies; Health Knowledge, Attitudes, Practice; Humans; Inhalant Abuse; Nitrous Oxid | 2023 |
[Severe neurologic and psychiatric symptoms after extensive use of nitrous oxide].
Topics: Humans; Nitrous Oxide; Substance-Related Disorders | 2023 |
Skin hyperpigmentation: a rare presenting symptom of nitrous oxide abuse.
Topics: China; Female; Humans; Hyperpigmentation; Illicit Drugs; Male; Nervous System Diseases; Nitrous Oxid | 2020 |
Increasing illicit use of nitrous oxide in presentations to NSW emergency departments.
Topics: Adolescent; Adult; Criminal Behavior; Emergency Service, Hospital; Female; Humans; Inhalant Abuse; M | 2019 |
Encephalitis secondary to nitrous oxide and vitamin B
Topics: Adult; Confusion; Diagnosis, Differential; Encephalitis; Female; Humans; Illicit Drugs; Nitrous Oxid | 2019 |
Nitrous Oxide Inhalant Use Disorder Preceding Symptoms Concerning for Primary Psychotic Illness.
Topics: Humans; Illicit Drugs; Male; Nitrous Oxide; Psychoses, Substance-Induced; Risk Factors; Substance-Re | 2020 |
Isolated cortical vein thrombosis after nitrous oxide use in a young woman: a case report.
Topics: Adult; Cerebral Veins; Female; Humans; Intracranial Thrombosis; Nitrous Oxide; Substance-Related Dis | 2020 |
No laughing matter - Myeloneuropathy due to heavy chronic nitrous oxide abuse.
Topics: Adult; Analgesics, Non-Narcotic; Emergency Service, Hospital; Female; Humans; Magnetic Resonance Ima | 2021 |
Associations of socio-demographic characteristics, well-being, school absenteeism, and substance use with recreational nitrous oxide use among adolescents: A cross-sectional study.
Topics: Absenteeism; Adolescent; Binge Drinking; Cross-Sectional Studies; Educational Status; Female; Humans | 2021 |
Appearance of hypersegmented neutrophils in the peripheral blood associated with subacute combined degeneration of the spinal cord due to nitrous oxide abuse.
Topics: Adult; Anesthetics, Inhalation; Humans; Male; Neutrophils; Nitrous Oxide; Spinal Cord; Subacute Comb | 2021 |
[Thromboembolisms due to recreational use of nitrous oxide].
Topics: Female; Humans; Illicit Drugs; Male; Nervous System Diseases; Nitrous Oxide; Peripheral Nervous Syst | 2021 |
Problematic Use of Nitrous Oxide by Young Moroccan-Dutch Adults.
Topics: Adolescent; Ethnicity; Humans; Nitrous Oxide; Qualitative Research; Substance-Related Disorders; You | 2021 |
Electrophysiological characteristics of patients with nitrous oxide abuse.
Topics: Adolescent; Adult; Diabetic Neuropathies; Extremities; Female; Guillain-Barre Syndrome; Humans; Male | 2021 |
Nitrous Oxide-Induced Neuropathy among Recreational Users in Vietnam.
Topics: Adolescent; Adult; Humans; Nervous System Diseases; Nitrous Oxide; Peripheral Nervous System Disease | 2021 |
Nitrous Oxide Abuse Associated with Severe Thromboembolic Complications.
Topics: Administration, Inhalation; Adult; Anticoagulants; Embolectomy; Female; Hallucinogens; Humans; Illic | 2021 |
No laughing matter.
Topics: Anesthetics, Inhalation; Demyelinating Diseases; Humans; Nitrous Oxide; Substance-Related Disorders; | 2017 |
[MEOPA use practices in a university hospital: Which conformity?]
Topics: Analgesics; Cross-Sectional Studies; France; Guideline Adherence; Health Care Surveys; Health Person | 2017 |
Adoniram Judson Shurtleff: a Tragic Picture of Anesthetic Drug Abuse.
Topics: Anesthetics; Death; History, 19th Century; Massachusetts; Nitrous Oxide; Substance-Related Disorders | 2017 |
Is nitrous oxide really that joyful?
Topics: Anemia, Hemolytic; Female; Humans; Leukopenia; Nitrous Oxide; Paresis; Substance-Related Disorders; | 2017 |
Nitrous oxide abuse presenting with acute psychosis and peripheral neuropathy.
Topics: Analgesics, Non-Narcotic; Humans; Nitrous Oxide; Peripheral Nervous System Diseases; Psychoses, Subs | 2018 |
No laughing matter: subacute degeneration of the spinal cord due to nitrous oxide inhalation.
Topics: Adolescent; Adult; Ataxia; Diagnosis, Differential; Female; Humans; Magnetic Resonance Imaging; Male | 2018 |
Subacute Combined Degeneration from Recreational Nitrous Oxide Inhalation.
Topics: Administration, Inhalation; Adult; Anesthetics; Humans; Magnetic Resonance Imaging; Male; Nitrous Ox | 2018 |
Laughter isn't always the best medicine.
Topics: Health Education; Humans; Illicit Drugs; Laughter; Nitrous Oxide; Substance-Related Disorders | 2018 |
Subacute progressive sensorimotor symptoms.
Topics: Adult; Diagnosis, Differential; Female; Humans; Magnetic Resonance Imaging; Neurodegenerative Diseas | 2019 |
My story: "I didn't think it was addictive"!
Topics: Dentists; Humans; Nitrous Oxide; Oklahoma; Substance-Related Disorders | 2012 |
Subacute combined degeneration of the spinal cord following recreational nitrous oxide use.
Topics: Female; Humans; Magnetic Resonance Imaging; Nitrous Oxide; Physical Therapy Modalities; Spinal Cord; | 2013 |
Nitrous oxide induced myeloneuropathy: a case report.
Topics: Adult; Contrast Media; Diagnosis, Differential; Humans; Magnetic Resonance Imaging; Male; Nitrous Ox | 2014 |
Nitrous oxide myelopathy in a pediatric patient.
Topics: Administration, Inhalation; Adolescent; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Diagnosis | 2014 |
A 23-year-old man with acute onset paresthesias and gait ataxia.
Topics: Aerosol Propellants; Gait Ataxia; Hematinics; Humans; Male; Nitrous Oxide; Paresthesia; Substance-Re | 2014 |
Predicting addictive vulnerability: individual differences in initial responding to a drug's pharmacological effects.
Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Body Temperature Regulation; Calorimet | 2015 |
Rehabilitation essential in the recovery of multifactorial subacute combined degeneration.
Topics: Adult; Alcoholism; Anemia, Pernicious; Humans; Male; Nitrous Oxide; Subacute Combined Degeneration; | 2015 |
Subacute combined degeneration of the spinal cord in a patient abusing nitrous oxide and self-medicating with cyanocobalamin.
Topics: Adult; Female; Humans; Magnetic Resonance Imaging; Nitrous Oxide; Self Medication; Spinal Cord Disea | 2015 |
The increasing recreational use of nitrous oxide: history revisited.
Topics: Anesthetics, Inhalation; History, 18th Century; History, 19th Century; History, 20th Century; Histor | 2016 |
Nitrous Oxide Abuse and Vitamin B12 Action in a 20-Year-Old Woman: A Case Report.
Topics: Adult; Demyelinating Diseases; Female; Humans; Methylmalonic Acid; Nitrous Oxide; Paresthesia; Spina | 2015 |
PHEDRE trial protocol - observational study of the prevalence of problematic use of Equimolar Mixture of Oxygen and Nitrous Oxide (EMONO) and analgesics in the French sickle-cell disease population.
Topics: Adolescent; Adult; Analgesics; Anemia, Sickle Cell; Child; Female; France; Humans; Male; Nitrous Oxi | 2015 |
Up: The rise of nitrous oxide abuse. An international survey of contemporary nitrous oxide use.
Topics: Adult; Dose-Response Relationship, Drug; Female; Hallucinations; Humans; Illicit Drugs; Male; Nitrou | 2016 |
'Whippits': nitrous oxide gas inhalation as recreational drug use.
Topics: Humans; Illicit Drugs; Nitrous Oxide; Substance-Related Disorders | 2016 |
Nitrous Oxide-induced Subacute Combined Degeneration Presenting with Dystonia and Pseudoathetosis: A Case Report.
Topics: Adult; Athetosis; Dystonia; Female; Gait Disorders, Neurologic; Humans; Nitrous Oxide; Subacute Comb | 2016 |
An adjusting-dose procedure for assessing the reinforcing effects of nitrous oxide with humans.
Topics: Adult; Anesthetics, Inhalation; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Hum | 2008 |
The hospital as a source of free inhalant drugs.
Topics: Adolescent; Anesthetics, Inhalation; Belgium; Hospitals; Humans; Nitrous Oxide; Security Measures; S | 2009 |
Peripheral neuropathy following nitrous oxide abuse.
Topics: Adult; Humans; Male; Nitrous Oxide; Peripheral Nervous System Diseases; Substance-Related Disorders | 2010 |
Nitrous oxide inhalation among adolescents: prevalence, correlates, and co-occurrence with volatile solvent inhalation.
Topics: Administration, Inhalation; Adolescent; Female; Humans; Male; Nitrous Oxide; Prevalence; Solvents; S | 2009 |
Trends and pattern of drug abuse deaths in Maryland teenagers.
Topics: Adolescent; Age Distribution; Black People; Butanes; Cause of Death; Chlorofluorocarbons, Methane; C | 2011 |
Teaching NeuroImages: myelopathy due to B₁₂ deficiency in long-term colchicine treatment and nitrous oxide misuse.
Topics: Adult; Colchicine; Humans; Male; Nitrous Oxide; Spinal Cord Diseases; Substance-Related Disorders; V | 2011 |
Nitrous oxide myelopathy posing as spinal cord injury.
Topics: Anesthetics, Inhalation; Diagnosis, Differential; Humans; Male; Nitrous Oxide; Spinal Cord Diseases; | 2012 |
Nitrous oxide use in first-year students at Auckland University.
Topics: Adolescent; Adult; Cross-Sectional Studies; Female; Health Surveys; Humans; Illicit Drugs; Incidence | 2003 |
Nitrous oxide-oxygen: a new look at a very old technique.
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Anesthetics, Inhalation; Conscious Sedation; Fertility; | 2003 |
A BAG FULL OF LAUGHS.
Topics: Brain; Euphoria; Nitrous Oxide; Pharmacology; Substance-Related Disorders; Toxicology | 1964 |
Nitrous oxide "whippit" abuse presenting as clinical B12 deficiency and ataxia.
Topics: Adult; Anesthetics, Inhalation; Ataxia; Humans; Male; Nitrous Oxide; Substance-Related Disorders; Vi | 2004 |
"Whippets"-induced cobalamin deficiency manifesting as cervical myelopathy.
Topics: Adult; Humans; Magnetic Resonance Imaging; Male; Nitrous Oxide; Spinal Cord; Spinal Cord Diseases; S | 2004 |
Dentists' use, misuse, abuse or dependence on mood-altering substances.
Topics: Affect; Dentists; Diazepam; Humans; Male; Nitrous Oxide; Substance-Related Disorders; Suicide; Tobac | 2004 |
Nitrous oxide inhalation as a cause of cervical myelopathy.
Topics: Administration, Inhalation; Adult; Cervical Vertebrae; Humans; Magnetic Resonance Imaging; Male; Nit | 2005 |
You are not alone.
Topics: Alcoholism; Anesthetics, Inhalation; Dentists; Humans; Nitrous Oxide; Professional Impairment; Subst | 2005 |
Symposium: psychotropic analgesic nitrous oxide (PAN): mechanisms of action and use for treating substance abuse withdrawal presented at 8th world congress of biological psychiatry Vienna (2 July 2005) in memoriam Frederick J Lichtigfeld (1933-2005).
Topics: Analgesics, Non-Narcotic; Animals; Biological Psychiatry; Humans; Nitrous Oxide; Substance-Related D | 2006 |
A case of unusual substance abuse causing myeloneuropathy.
Topics: Adult; Female; Humans; Magnetic Resonance Imaging; Nitrous Oxide; Subacute Combined Degeneration; Su | 2007 |
Systems-level adaptations explain chronic tolerance development to nitrous oxide hypothermia in young and mature rats.
Topics: Administration, Inhalation; Allostasis; Animals; Body Temperature; Body Temperature Regulation; Calo | 2007 |
Nitrous oxide abuse: dentistry's unique addiction.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anesthetics, Inhalation; Dentistry; Denti | 2006 |
Direct evidence for systems-level modulation of initial drug (in)sensitivity in rats.
Topics: Administration, Inhalation; Animals; Body Temperature; Body Temperature Regulation; Calorimetry; Cal | 2007 |
Neurotoxicity of nitrous oxide: multimodal evoked potentials in an abuser.
Topics: Adult; Anesthetics, Inhalation; Evoked Potentials, Somatosensory; Humans; Magnetic Resonance Imaging | 2007 |
[Pneumothorax following recreational inhalation of nitrous oxide].
Topics: Adult; Anesthetics, Inhalation; Drainage; Humans; Illicit Drugs; Male; Nitrous Oxide; Pneumothorax; | 2007 |
Paralysis caused by "nagging".
Topics: Adult; Female; Humans; Malnutrition; Nitrous Oxide; Paralysis; Spinal Cord Diseases; Substance Abuse | 2007 |
Nitrous oxide inhalation as a fad. Dangers in uncontrolled sniffing for psychedelic effect.
Topics: Adolescent; Adult; California; Hallucinogens; Heroin; Humans; Nitrous Oxide; Substance-Related Disor | 1967 |
Neuropathy after nitrous oxide abuse.
Topics: Female; Humans; Male; Neuromuscular Diseases; Nitrous Oxide; Peripheral Nervous System Diseases; Sub | 1980 |
Myeloneuropathy and macrocytosis associated with nitrous oxide abuse.
Topics: Adult; Anemia, Macrocytic; Anemia, Megaloblastic; Humans; Male; Nitrous Oxide; Peripheral Nervous Sy | 1983 |
Nitrous oxide-induced myeloneuropathy.
Topics: Adult; Humans; Hypesthesia; Leg; Male; Muscle Hypotonia; Muscles; Nitrous Oxide; Paresthesia; Periph | 1983 |
Nitrous oxide: a potentially lethal euphoriant inhalant.
Topics: Adult; Humans; Male; Nitrous Oxide; Sensation; Substance-Related Disorders | 1984 |
N20 and chemically dependent patients.
Topics: Anesthesia, Dental; Humans; Nitrous Oxide; Substance-Related Disorders | 1984 |
Drug abuse. Its relationship to dental practice.
Topics: Amphetamines; Benzodiazepines; Cannabis; Cocaine; Dental Care; Dentists; Drug Prescriptions; Halluci | 1984 |
Management of acute and postoperative pain.
Topics: Acute Disease; Anesthetics, Local; Cryosurgery; Electric Stimulation Therapy; Humans; Injections; Na | 1983 |
Personality, prior drug use, and introspective experience during nitrous oxide intoxication.
Topics: Adult; Euphoria; Humans; Internal-External Control; Male; Nitrous Oxide; Personality Inventory; Set, | 1983 |
Subacute toxic delirium following nitrous oxide abuse.
Topics: Acute Disease; Adult; Brain Diseases; Delirium; Humans; Male; Nitrous Oxide; Substance-Related Disor | 1983 |
Nitrous oxide: use and abuse in dentistry.
Topics: Anesthesia, Dental; Dentists; Humans; Nitrous Oxide; Substance-Related Disorders | 1980 |
Effects of nitrous oxide.
Topics: Adolescent; Adult; Anesthesia, Dental; Anxiety; Child; Humans; Nitrous Oxide; Substance-Related Diso | 1981 |
Nitrous oxide-induced myeloneuropathy: report of cases.
Topics: Adult; Dentists; Humans; Male; Nitrous Oxide; Occupational Diseases; Paresthesia; Substance-Related | 1981 |
Homemade nitrous oxide: no laughing matter.
Topics: Adult; Drug Contamination; Humans; Lung Diseases; Male; Nitrogen Dioxide; Nitrous Oxide; Substance-R | 1982 |
Nitrous oxide abuse: a new cause of pneumomediastinum.
Topics: Adult; Humans; Male; Mediastinal Emphysema; Nitrous Oxide; Radiography; Substance-Related Disorders | 1982 |
Physical dependence on nitrous oxide in mice: resemblance to alcohol but not to opiate withdrawal.
Topics: Animals; Ethanol; Humans; Male; Mice; Naloxone; Nitrous Oxide; Opioid-Related Disorders; Seizures; S | 1981 |
A study of analgesic and dependence producing actions of nitrous oxide in mice.
Topics: Analgesics; Animals; Drug Implants; Humans; Male; Mice; Morphine Dependence; Naloxone; Nitrous Oxide | 1982 |
Nitrous oxide availability.
Topics: Aerosols; Drug Labeling; Household Products; Humans; Nitrous Oxide; Substance-Related Disorders; Uni | 1980 |
Death from inhalant abuse: toxicological and pathological evaluation of 34 cases.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Chlorofluorocarbons, Methane; Chromatography, Gas; Female; | 1980 |
Nitrous oxide hazards.
Topics: Animals; Environmental Exposure; Health Workforce; Humans; Nitrous Oxide; Substance-Related Disorder | 1980 |
Toxicologic states treated in an Emergency Department.
Topics: Alcoholism; Camphor; Emergency Service, Hospital; Ethylene Oxide; Humans; Illicit Drugs; Nitrous Oxi | 1980 |
Nitrous oxide and the terminology of 'abuse' and 'use'.
Topics: Administration, Inhalation; Humans; Mental Recall; Nitrous Oxide; Psychomotor Performance; Substance | 1995 |
Nitrous oxide has a very low abuse potential.
Topics: Diagnosis, Differential; Humans; Motivation; Nitrous Oxide; Risk Factors; Substance-Related Disorder | 1995 |
Accidental death by nitrous oxide inhalation.
Topics: Adult; Asphyxia; Fatal Outcome; Humans; Male; Nitrous Oxide; Substance-Related Disorders | 1995 |
Nitrous oxide: a serious look at laughing gas.
Topics: Humans; Legislation, Drug; Nitrous Oxide; Substance-Related Disorders | 1993 |
The Texas Dental Peer Assistance Program and the impaired dental professional.
Topics: Alcoholism; Dentists; Humans; Licensure, Dental; Nitrous Oxide; Peer Group; Professional Impairment; | 1993 |
Behavioral and electrophysiological aspects of nitrous oxide dependence.
Topics: Animals; Behavior, Animal; Electrodes, Implanted; Electrophysiology; Evoked Potentials, Visual; Male | 1994 |
Frostbite of the face after recreational misuse of nitrous oxide.
Topics: Facial Injuries; Frostbite; Humans; Male; Middle Aged; Nitrous Oxide; Substance-Related Disorders | 1996 |
"Nanging": another cause of nitrous oxide neurotoxicity.
Topics: Adult; Female; Humans; Nitrous Oxide; Peripheral Nervous System Diseases; Substance-Related Disorder | 1997 |
Myeloneuropathy from whipped cream bulbs presenting as conversion disorder.
Topics: Adult; Central Nervous System Diseases; Conversion Disorder; Diagnosis, Differential; Female; Humans | 1997 |
Nitrous oxide abuse from whipped cream dispenser chargers.
Topics: Administration, Inhalation; Humans; Nitrous Oxide; Substance-Related Disorders | 1997 |
Myelopathy caused by nitrous oxide toxicity.
Topics: Adult; Humans; Magnetic Resonance Imaging; Male; Neck; Nitrous Oxide; Spinal Cord; Spinal Cord Disea | 1998 |
Chemically dependent dentists fight back with help from the profession.
Topics: Dentists; Humans; Nitrous Oxide; Professional Impairment; Substance-Related Disorders | 1998 |
Deaths associated with inhalant abuse in Virginia from 1987 to 1996.
Topics: Administration, Inhalation; Adolescent; Adult; Butanes; Female; Humans; Male; Middle Aged; Nitrous O | 1999 |
Nitrous oxide myelopathy in an abuser of whipped cream bulbs.
Topics: Adult; Cervical Vertebrae; Humans; Male; Methionine; Nitrous Oxide; Spinal Cord Diseases; Substance- | 2000 |
Inhalant use and addiction in Canada.
Topics: Amyl Nitrite; Canada; Emergency Treatment; Humans; Needs Assessment; Nitrous Oxide; Oils, Volatile; | 2001 |
[Polyneuropathy and myelopathy in N2O abuse within the scope of multiple drug abuse].
Topics: Adult; Humans; Illicit Drugs; Male; Neurologic Examination; Nitrous Oxide; Polyneuropathies; Spinal | 2001 |
Expectancies of sexual "escape" and sexual risk among drug and alcohol-involved gay and bisexual men.
Topics: Adult; Bisexuality; Black or African American; Cocaine; Denial, Psychological; HIV Infections; Homos | 2001 |
Neurologic problems associated with chronic nitrous oxide abuse in a non-healthcare worker.
Topics: Humans; Inhalation Exposure; Male; Middle Aged; Nervous System Diseases; Nitrous Oxide; Substance-Re | 2001 |
Convulsions in mice after anesthesia.
Topics: Anesthetics; Animals; Cyclopropanes; Ether; Ethers; Ethylenes; Humans; Methyldopa; Mice; Mice, Inbre | 1979 |
Myeloneuropathy after prolonged exposure to nitrous oxide.
Topics: Adult; Anesthesia, Dental; Arm; Dental Technicians; Dentists; Erectile Dysfunction; Humans; Leg; Mal | 1978 |
Polyneuropathy from inhalation of N2O cartridges through a whipped-cream dispenser.
Topics: Adult; Dairy Products; Electromyography; Female; Humans; Neural Conduction; Nitrous Oxide; Periphera | 1978 |
Neuropathy following abuse of nitrous oxide.
Topics: Adult; Dentistry; Humans; Male; Medical Laboratory Science; Neural Conduction; Nitrous Oxide; Periph | 1978 |
Nitrous oxide-induced myelopathy-neuropathy: potential for chronic misuse by dentists.
Topics: Adult; Dentists; Humans; Male; Nitrous Oxide; Paresthesia; Self Medication; Substance-Related Disord | 1979 |
"Recreational" misuse of nitrous oxide.
Topics: Adult; Humans; Male; Nitrous Oxide; Paresthesia; Substance-Related Disorders | 1979 |
Not a laughing matter [ letter].
Topics: Diagnosis, Differential; Humans; Nitrous Oxide; Substance-Related Disorders | 1979 |
Sniffing out nitrous problems.
Topics: Anesthesia, Dental; Humans; Nitrous Oxide; Substance-Related Disorders | 1979 |
Preclinical behavioral toxicology of inhalant solvents.
Topics: Anesthetics; Animals; Behavior; Female; Halothane; Humans; Hydrocarbons, Chlorinated; Male; Nitrous | 1977 |
Nervous laughter--or, hazards of laughing gas.
Topics: Humans; Nervous System Diseases; Nitrous Oxide; Occupational Diseases; Substance-Related Disorders | 1979 |
Tolerance to and dependence on inhalational anesthetics.
Topics: Anesthesia, Inhalation; Anesthetics; Animals; Cyclopropanes; Drug Tolerance; Humans; Isoflurane; Mic | 1979 |
The grocery store high.
Topics: Adolescent; Aerosol Propellants; Aerosols; Child; Child, Preschool; Dairy Products; Humans; Male; Ni | 1978 |
Nitrous oxide analgesia--possible addiction.
Topics: Diazepam; Humans; Nitrous Oxide; Substance-Related Disorders | 1975 |
Asphyxial deaths from the recreational use of nitrous oxide.
Topics: Adolescent; Adult; Aerosols; Asphyxia; Cause of Death; Humans; Male; Middle Aged; Nitrous Oxide; Oxy | 1992 |
Atypical autoerotic deaths.
Topics: Adult; Chlorofluorocarbons, Methane; Cocaine; Humans; Hydrocarbons, Halogenated; Male; Nitrites; Nit | 1992 |
"I'm a chemically dependent dentist"/ Case 1. A near fatal combination.
Topics: Adult; Dentists; Humans; Male; Nitrous Oxide; Physician Impairment; Substance-Related Disorders | 1990 |
Nitrous oxide abuse presenting as premature exhaustion of Sodasorb.
Topics: Calcium Compounds; Humans; Nitrous Oxide; Oxides; Sodium Hydroxide; Substance-Related Disorders; Tim | 1991 |
Reversible myeloneuropathy of nitrous oxide abuse: serial electrophysiological studies.
Topics: Adult; Ataxia; Electromyography; Electrophysiology; Female; Humans; Male; Neural Conduction; Nitrous | 1991 |
Nitrous oxide and its abuse.
Topics: Hematopoiesis; Humans; Nervous System Diseases; Nitrous Oxide; Students, Dental; Students, Medical; | 1991 |
[Is there a connection between obstetrical nitrous oxide analgesia and amphetamine abuse?].
Topics: Amphetamine; Analgesia, Obstetrical; Female; Humans; Maternal-Fetal Exchange; Nitrous Oxide; Pregnan | 1991 |
Nitrous oxide becomes the vice of dentists.
Topics: Dentists; Humans; Nitrous Oxide; Substance-Related Disorders | 1990 |
Nitrous oxide abuse presenting as premature exhaustion of sodasorb.
Topics: Anesthesiology; Humans; Nitrous Oxide; Operating Rooms; Substance-Related Disorders | 1990 |
Fatal abuse of nitrous oxide in the workplace.
Topics: Humans; Nitrous Oxide; Occupational Diseases; Substance-Related Disorders; United States; United Sta | 1990 |
[Administration of laughing gas during labor may cause later amphetamine addiction in the offspring].
Topics: Amphetamines; Anesthetics, Inhalation; Female; Humans; Infant, Newborn; Labor, Obstetric; Nitrous Ox | 1989 |
[What does exposure to nitrous oxide during labor mean for the development of amphetamine abuse in children?].
Topics: Adolescent; Adult; Amphetamine; Female; Humans; Maternal-Fetal Exchange; Nitrous Oxide; Pregnancy; S | 1989 |
[Laughing gas and amphetamine abuse].
Topics: Amphetamine; Anesthesia, Obstetrical; Female; Humans; Maternal-Fetal Exchange; Nitrous Oxide; Pregna | 1989 |
Treatment of acute drug abuse reactions.
Topics: Central Nervous System Depressants; Central Nervous System Stimulants; Cocaine; Hallucinogens; Human | 1987 |
Nitrous oxide: clinical and electrophysiologic investigation of neurologic complications.
Topics: Adult; Evoked Potentials, Somatosensory; Evoked Potentials, Visual; Humans; Male; Median Nerve; Nerv | 1986 |
Solvent-inhalant abuse.
Topics: Adolescent; Adult; Age Factors; Humans; Nitrites; Nitrous Oxide; Solvents; Substance-Related Disorde | 1988 |
Nitrous oxide warning.
Topics: Adolescent; Asphyxia; Drug Storage; Humans; Male; Nitrous Oxide; Substance-Related Disorders | 1988 |
Nitrous oxide abuse.
Topics: Humans; Male; Nitrous Oxide; Substance-Related Disorders | 1988 |
Chemical dependency: the road to recovery.
Topics: Adult; Alcoholism; American Dental Association; Child; Cocaine; Denial, Psychological; Dentists; Fam | 1987 |
Nitrous oxide sedation/analgesia in emergency medicine.
Topics: Analgesia; Anxiety; Emergencies; Emergency Medicine; Environmental Pollution; Female; Fetal Diseases | 1985 |
Pattern-reversal visual evoked potential in a case of nitrous oxide abuse and recovery.
Topics: Adult; Dentists; Diagnostic Errors; Evoked Potentials, Visual; Humans; Male; Multiple Sclerosis; Ner | 1985 |
The status of nitrous oxide in dentistry.
Topics: Analgesia; Anesthesia, Dental; Humans; Nitrous Oxide; Substance-Related Disorders | 1973 |
History and pharmacology of psychedelic drugs.
Topics: Amphetamine; Caffeine; Cannabis; Coca; Cocaine; Condiments; Ethanol; Ethyl Ethers; Hallucinogens; Hi | 1971 |
A bizarre tragedy.
Topics: Anesthesia, Inhalation; Humans; Nitrous Oxide; Substance-Related Disorders | 1969 |
Anaesthetic time-dose curves. VII. Experience with pentazocine.
Topics: Adjuvants, Anesthesia; Adult; Aged; Drug Prescriptions; Female; Halothane; Humans; Male; Meperidine; | 1971 |
Non-medical use of nitrous oxide: a preliminary report.
Topics: Humans; Michigan; Nitrous Oxide; Substance-Related Disorders | 1971 |