nitrous oxide has been researched along with Cerebral Palsy in 18 studies
Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine technical and clinical factors associated with pain when using an analgesic protocol with 50% nitrous oxide/oxygen and anesthetic cream (lidocaine and prilocaine, Emla(®)) for children with cerebral palsy undergoing botulinum toxin injections." | 9.15 | Determining the technical and clinical factors associated with pain for children undergoing botulinum toxin injections under nitrous oxide and anesthetic cream. ( Blajan, V; Brochard, S; Garlantezec, R; Houx, L; Le Moine, P; Lefranc, J; Lempereur, M; Peudenier, S; Rémy-Néris, O, 2011) |
| "The efficacy of nitrous oxide (N2O) inhalation on the elevated orofacial muscle tonus during dental treatment in patients with cerebral palsy (CP) was studied by measuring the mean frequency of electromyographic (EMG) discharge, blood pressure (BP) and heart rate (HR) taking mentally retarded patients (MR) as a control." | 7.72 | Effect of nitrous oxide on dental patients with cerebral palsy -- using an electromyogram (EMG) from orofacial muscles as an index. ( Akasaka, M; Nakajima, I; Uchida, A; Yamaguchi, T; Yoshida, M, 2003) |
| "Pain was evaluated with the Children's Hospital of Eastern Ontario Pain Scale (CHEOPS), the Visual Analogue Scale (VAS) and the Face Pain Scale (FPS) for the children and with a VAS for the parents." | 5.35 | Effectiveness of nitrous oxide and analgesic cream (lidocaine and prilocaine) for prevention of pain during intramuscular botulinum toxin injections in children. ( Blajan, V; Brochard, S; Le Moine, P; Lefranc, J; Lempereur, M; Peudenier, S; Rémy-Néris, O, 2009) |
| "Abnormal spinal reflexes seen in spastic diplegia can be abolished by inhaled N2O." | 5.29 | Nitrous oxide depresses the H-reflex in children with cerebral palsy. ( Logigian, EL; Madsen, JR; Prahl, PA; Scott, RM; Soriano, SG, 1995) |
| "To determine technical and clinical factors associated with pain when using an analgesic protocol with 50% nitrous oxide/oxygen and anesthetic cream (lidocaine and prilocaine, Emla(®)) for children with cerebral palsy undergoing botulinum toxin injections." | 5.15 | Determining the technical and clinical factors associated with pain for children undergoing botulinum toxin injections under nitrous oxide and anesthetic cream. ( Blajan, V; Brochard, S; Garlantezec, R; Houx, L; Le Moine, P; Lefranc, J; Lempereur, M; Peudenier, S; Rémy-Néris, O, 2011) |
| "This randomized, double-blind, placebo-controlled study compared the efficacy of inhaled nitrous oxide (N(2)O) with enteral midazolam for sedation of children with cerebral palsy (CP) undergoing botulinum toxin A (BoNT-A) injections." | 5.13 | Effectiveness of sedation using nitrous oxide compared with enteral midazolam for botulinum toxin A injections in children. ( Krach, LE; Rivard, PF; Wendorf, HR; Zier, JL, 2008) |
| " A significant odds ratio related to decreased SpO2 was observed for age, sex, midazolam and propofol levels, concurrent use of nitrous oxide, cerebral palsy, Down syndrome, and mental retardation." | 3.79 | Risk factors with intravenous sedation for patients with disabilities. ( Fukayama, H; Ishikawa, M; Jinno, S; Kohase, H; Kunimori, H; Miwa, Z; Nakamura, Z; Okumura, H; Shimoyama, K; Tamaki, Y; Yoshikawa, F, 2013) |
| "The efficacy of nitrous oxide (N2O) inhalation on the elevated orofacial muscle tonus during dental treatment in patients with cerebral palsy (CP) was studied by measuring the mean frequency of electromyographic (EMG) discharge, blood pressure (BP) and heart rate (HR) taking mentally retarded patients (MR) as a control." | 3.72 | Effect of nitrous oxide on dental patients with cerebral palsy -- using an electromyogram (EMG) from orofacial muscles as an index. ( Akasaka, M; Nakajima, I; Uchida, A; Yamaguchi, T; Yoshida, M, 2003) |
| "Pain was evaluated with the Children's Hospital of Eastern Ontario Pain Scale (CHEOPS), the Visual Analogue Scale (VAS) and the Face Pain Scale (FPS) for the children and with a VAS for the parents." | 1.35 | Effectiveness of nitrous oxide and analgesic cream (lidocaine and prilocaine) for prevention of pain during intramuscular botulinum toxin injections in children. ( Blajan, V; Brochard, S; Le Moine, P; Lefranc, J; Lempereur, M; Peudenier, S; Rémy-Néris, O, 2009) |
| "Abnormal spinal reflexes seen in spastic diplegia can be abolished by inhaled N2O." | 1.29 | Nitrous oxide depresses the H-reflex in children with cerebral palsy. ( Logigian, EL; Madsen, JR; Prahl, PA; Scott, RM; Soriano, SG, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (16.67) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 7 (38.89) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Delafontaine, A | 1 |
| Presedo, A | 1 |
| Mohamed, D | 1 |
| Lopes, D | 1 |
| Wood, C | 1 |
| Alberti, C | 1 |
| Cantador-Hornero, M | 1 |
| Jiménez-Espuch, P | 1 |
| de Torres-Garcia, I | 1 |
| Contreras-Jiménez, M | 1 |
| Martínez-Mezo, GL | 1 |
| Morales de Los Santos, JM | 1 |
| Fernández-Jurado, MI | 1 |
| Tirado-Reyes, M | 1 |
| Yoshikawa, F | 1 |
| Tamaki, Y | 1 |
| Okumura, H | 1 |
| Miwa, Z | 1 |
| Ishikawa, M | 1 |
| Shimoyama, K | 1 |
| Nakamura, Z | 1 |
| Kunimori, H | 1 |
| Jinno, S | 1 |
| Kohase, H | 1 |
| Fukayama, H | 1 |
| Zier, JL | 1 |
| Rivard, PF | 1 |
| Krach, LE | 1 |
| Wendorf, HR | 1 |
| Abdallah, C | 1 |
| Hannallah, R | 1 |
| Gubbay, A | 1 |
| Langdon, K | 1 |
| Kumar, R | 1 |
| Sneade, C | 1 |
| Littler, K | 1 |
| Brochard, S | 2 |
| Blajan, V | 2 |
| Lempereur, M | 2 |
| Le Moine, P | 2 |
| Peudenier, S | 2 |
| Lefranc, J | 2 |
| Rémy-Néris, O | 2 |
| Garlantezec, R | 1 |
| Houx, L | 1 |
| Forrester, M | 1 |
| Srinivasan, J | 1 |
| Mihrshahi, S | 1 |
| Waugh, M | 1 |
| O'Flaherty, S | 1 |
| Rice, J | 1 |
| Graham, K | 1 |
| Scheinberg, A | 1 |
| Soudant, DL | 1 |
| Staal, HM | 1 |
| Witlox, AM | 1 |
| Vles, JS | 1 |
| Yoshida, M | 1 |
| Nakajima, I | 1 |
| Uchida, A | 1 |
| Yamaguchi, T | 1 |
| Akasaka, M | 1 |
| DUNNOM, WR | 1 |
| Gambart, G | 1 |
| Mette, F | 1 |
| Pellot, AS | 1 |
| Richard, I | 1 |
| Soriano, SG | 1 |
| Logigian, EL | 1 |
| Scott, RM | 1 |
| Prahl, PA | 1 |
| Madsen, JR | 1 |
| Theroux, MC | 1 |
| Brandom, BW | 1 |
| Zagnoev, M | 1 |
| Kettrick, RG | 1 |
| Miller, F | 1 |
| Ponce, C | 1 |
| Sanders, RA | 1 |
| Duncan, PG | 1 |
| McCullough, DW | 1 |
| Guida, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Evaluation of the Efficacy of MEOPA Used to Obtain Better ROM Immediately After Multilevel Surgery in Children With Spastic Diplegia, Quadriplegia or Hemiplegia."[NCT00632528] | Phase 3 | 64 participants (Actual) | Interventional | 2008-03-31 | Completed | ||
| Chronic Postsurgical Pain in Cerebral Palsy[NCT05764681] | 500 participants (Anticipated) | Observational | 2023-03-31 | Not yet recruiting | |||
| Evaluation of the Effect of the Presence Of Clowns on Pain and Anxiety Seen During Injections Botulinum Toxin in Child[NCT03149263] | 80 participants (Actual) | Observational | 2015-11-10 | Completed | |||
| Validity of Bispectral Index Monitoring During Deep Sedation for Botulinum Toxin Injection in Children With Cerebral Palsy[NCT02096549] | 22 participants (Actual) | Observational | 2014-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 trials available for nitrous oxide and Cerebral Palsy
| Article | Year |
|---|---|
Equimolar mixture of nitroux oxyde and oxygen during post-operative physiotherapy in patients with cerebral palsy: A randomized, double-blind, placebo-controlled study.
Topics: Acute Pain; Adolescent; Analgesics, Non-Narcotic; Cerebral Palsy; Child; Double-Blind Method; Female | 2017 |
Equimolar mixture of nitroux oxyde and oxygen during post-operative physiotherapy in patients with cerebral palsy: A randomized, double-blind, placebo-controlled study.
Topics: Acute Pain; Adolescent; Analgesics, Non-Narcotic; Cerebral Palsy; Child; Double-Blind Method; Female | 2017 |
Equimolar mixture of nitroux oxyde and oxygen during post-operative physiotherapy in patients with cerebral palsy: A randomized, double-blind, placebo-controlled study.
Topics: Acute Pain; Adolescent; Analgesics, Non-Narcotic; Cerebral Palsy; Child; Double-Blind Method; Female | 2017 |
Equimolar mixture of nitroux oxyde and oxygen during post-operative physiotherapy in patients with cerebral palsy: A randomized, double-blind, placebo-controlled study.
Topics: Acute Pain; Adolescent; Analgesics, Non-Narcotic; Cerebral Palsy; Child; Double-Blind Method; Female | 2017 |
[Sedation-analgesia protocol for the injection of botulinum toxin A in cerebral palsy].
Topics: Adolescent; Analgesia; Anesthetics, Local; Benzodiazepines; Botulinum Toxins, Type A; Cerebral Palsy | 2019 |
Effectiveness of sedation using nitrous oxide compared with enteral midazolam for botulinum toxin A injections in children.
Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Child, Preschool; Double-Blind Method; | 2008 |
Effectiveness of sedation using nitrous oxide compared with enteral midazolam for botulinum toxin A injections in children.
Topics: Adolescent; Anesthetics, Inhalation; Anesthetics, Intravenous; Botulinum Toxins, Type A; Cerebral Pa | 2009 |
Determining the technical and clinical factors associated with pain for children undergoing botulinum toxin injections under nitrous oxide and anesthetic cream.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Botulinum Toxins, Type A; Cerebral Palsy; C | 2011 |
[Evaluation of analgesic protocol with nitrous oxide and EMLA cream during botulinum toxin injections in children].
Topics: Adolescent; Analgesics, Non-Narcotic; Anesthetics, Local; Botulinum Toxins, Type A; Cerebral Palsy; | 2007 |
Dose response of succinylcholine at the adductor pollicis of children with cerebral palsy during propofol and nitrous oxide anesthesia.
Topics: Anesthesia, General; Cerebral Palsy; Child; Child, Preschool; Cholinesterases; Dose-Response Relatio | 1994 |
11 other studies available for nitrous oxide and Cerebral Palsy
| Article | Year |
|---|---|
Risk factors with intravenous sedation for patients with disabilities.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Dental; Anesthes | 2013 |
Dystonic reaction after Botox injection under nitrous oxide/oxygen and sevoflurane anesthesia.
Topics: Adolescent; Anesthesia, Inhalation; Anesthetics, Inhalation; Botulinum Toxins, Type A; Cerebral Pals | 2009 |
'Effectiveness of sedation using nitrous oxide compared with enteral midazolam for botulinum toxin A injections in children'.
Topics: Botulinum Toxins, Type A; Cerebral Palsy; Child; Conscious Sedation; Female; Humans; Hypnotics and S | 2009 |
Effectiveness of nitrous oxide and analgesic cream (lidocaine and prilocaine) for prevention of pain during intramuscular botulinum toxin injections in children.
Topics: Administration, Cutaneous; Administration, Inhalation; Adolescent; Anesthetics; Anti-Dyskinesia Agen | 2009 |
Conscious sedation or general anaesthetic for intramuscular botulinum toxin injections in children - a two centre cross-sectional prospective audit.
Topics: Botulinum Toxins, Type A; Cerebral Palsy; Female; Humans; Lidocaine; Male; Nitrous Oxide; Pain; Para | 2012 |
Conscious sedation or general anaesthetic for intramuscular botulinum toxin injections in children - a two centre cross-sectional prospective audit.
Topics: Botulinum Toxins, Type A; Cerebral Palsy; Female; Humans; Lidocaine; Male; Nitrous Oxide; Pain; Para | 2013 |
Effect of nitrous oxide on dental patients with cerebral palsy -- using an electromyogram (EMG) from orofacial muscles as an index.
Topics: Adult; Anesthetics, Inhalation; Blood Pressure; Cerebral Palsy; Electromyography; Facial Muscles; Fe | 2003 |
Operative dentistry for the cerebral palsied and difficult child patient under general anesthesia.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, General; Anesthesia, Inhalation; Cerebr | 1953 |
Nitrous oxide depresses the H-reflex in children with cerebral palsy.
Topics: Cerebral Palsy; Child, Preschool; Depression, Chemical; Female; H-Reflex; Humans; Male; Muscle Spast | 1995 |
Clinical experience with brain stem audiometry performed under general anesthesia.
Topics: Adolescent; Anesthesia, Inhalation; Anesthesia, Intravenous; Audiometry; Brain Stem; Cerebral Palsy; | 1979 |
[Advantages of conscious sedation in the handicapped].
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, General; Cerebral Palsy; Child; Dental Care for D | 1988 |