nitrous oxide has been researched along with Cardiac Diseases in 27 studies
Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nitrous oxide was administered to eight dogs with experimentally induced left anterior descending coronary artery (LAD) critical stenosis during fentanyl (100 micrograms/kg bolus plus 1." | 1.27 | Gradual or abrupt nitrous oxide administration in a canine model of critical coronary stenosis induces regional myocardial dysfunction that is worsened by halothane. ( Foëx, P; Lehot, JJ; Leone, BJ; Philbin, DM; Ryder, WA, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (74.07) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (18.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jain, D | 1 |
| Ma, HK | 1 |
| Buckley, N | 2 |
| Beattie, WS | 1 |
| Wijeysundera, DN | 1 |
| Chan, MTV | 1 |
| Peyton, PJ | 1 |
| Leslie, K | 1 |
| Paech, MJ | 1 |
| Sessler, DI | 1 |
| Wallace, S | 1 |
| Myles, PS | 1 |
| Galagher, W | 1 |
| Farrington, C | 1 |
| Ditoro, A | 1 |
| Baulch, S | 1 |
| Sidiropoulos, S | 1 |
| Bulach, R | 1 |
| Bryant, D | 1 |
| O'Loughlin, E | 1 |
| Mitteregger, V | 1 |
| Bolsin, S | 1 |
| Osborne, C | 1 |
| McRae, R | 1 |
| Backstrom, M | 1 |
| Cotter, R | 1 |
| March, S | 1 |
| Silbert, B | 1 |
| Said, S | 1 |
| Halliwell, R | 1 |
| Cope, J | 1 |
| Fahlbusch, D | 1 |
| Crump, D | 1 |
| Thompson, G | 1 |
| Jefferies, A | 1 |
| Reeves, M | 1 |
| Tidy, T | 1 |
| Schricker, T | 1 |
| Lattermann, R | 1 |
| Iannuzzi, D | 1 |
| Carroll, J | 1 |
| Jacka, M | 1 |
| Bryden, C | 1 |
| Badner, N | 1 |
| Tsang, MWY | 1 |
| Cheng, BCP | 1 |
| Fong, ACM | 1 |
| Chu, LCY | 1 |
| Koo, EGY | 1 |
| Mohd, N | 1 |
| Ming, LE | 1 |
| Campbell, D | 1 |
| McAllister, D | 1 |
| Walker, S | 1 |
| Olliff, S | 1 |
| Kennedy, R | 1 |
| Eldawlatly, A | 1 |
| Alzahrani, T | 1 |
| Chua, N | 1 |
| Sneyd, R | 1 |
| McMillan, H | 1 |
| Parkinson, I | 1 |
| Brennan, A | 1 |
| Balaji, P | 1 |
| Nightingale, J | 1 |
| Kunst, G | 1 |
| Dickinson, M | 1 |
| Subramaniam, B | 1 |
| Banner-Godspeed, V | 1 |
| Liu, J | 1 |
| Kurz, A | 1 |
| Hesler, B | 1 |
| Fu, AY | 1 |
| Egan, C | 1 |
| Fiffick, AN | 1 |
| Hutcherson, MT | 1 |
| Turan, A | 1 |
| Naylor, A | 1 |
| Obal, D | 1 |
| Cooke, E | 1 |
| Banchs, R | 1 |
| Lerman, J | 1 |
| Wald, SH | 1 |
| Nagele, P | 1 |
| Brown, F | 1 |
| Francis, A | 1 |
| Scott, MG | 1 |
| Gage, BF | 1 |
| Miller, JP | 1 |
| Sathitkarnmanee, T | 1 |
| Tribuddharat, S | 1 |
| Nonlhaopol, D | 1 |
| Thananun, M | 1 |
| Somdee, W | 1 |
| RAMSEY, LH | 1 |
| PUCKETT, W | 1 |
| JOSE, A | 1 |
| LACY, WW | 1 |
| Bunatjan, AA | 1 |
| Osypov, VP | 1 |
| Meshcherjakov, AV | 1 |
| Gillespie, WJ | 1 |
| Greene, DG | 1 |
| Karatzas, NB | 2 |
| Lee, GD | 1 |
| Bull, AP | 1 |
| Wald, C | 1 |
| Summers, L | 1 |
| Dauchot, PJ | 1 |
| Rasmussen, JP | 1 |
| Nicholson, DH | 1 |
| Divers, RT | 1 |
| Katona, PG | 1 |
| Zollinger, RM | 1 |
| Knoke, JD | 1 |
| Kyo, EW | 1 |
| Gravenstein, JS | 1 |
| Murkin, JM | 1 |
| Farrar, JK | 1 |
| McNeill, B | 1 |
| Gelb, AW | 1 |
| Lok, P | 1 |
| O'Connor, JP | 1 |
| Hernández González, S | 1 |
| Osorio Serna, M | 1 |
| Nava Tollaves, G | 1 |
| Leone, BJ | 1 |
| Philbin, DM | 1 |
| Lehot, JJ | 1 |
| Foëx, P | 1 |
| Ryder, WA | 1 |
| Weber, K | 1 |
| Gross, G | 1 |
| Scott, JG | 1 |
| Allan, D | 1 |
| Fabian, LW | 1 |
| Short, CE | 1 |
| Harrison, SG | 1 |
| Sellick, BA | 1 |
| Brown, RC | 1 |
| Munro, WD | 1 |
| Bannister, AK | 1 |
| Carnow, R | 1 |
| Kozam, RL | 1 |
| Landau, SM | 1 |
| Cubina, JM | 1 |
| Lukas, DS | 1 |
| Lee, Gde J | 1 |
| Zol'nikov, SM | 1 |
| Stepan'kov, IuL | 1 |
| Trekova, NA | 1 |
| Donawick, WJ | 1 |
| Nara, Y | 1 |
| Baue, AE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Large, Randomised, Parallel-group, Controlled Trial, With Patients Randomly Allocated to Either N2O-containing (70% N2O in Oxygen [FiO2 0.3]) or N2O-free (70% Nitrogen in Oxygen [FiO2 0.3]).[NCT00430989] | Phase 4 | 7,112 participants (Actual) | Interventional | 2007-04-30 | Completed | ||
| Evaluation of the Antidepressant Effects of Nitrous Oxide in People With Major Depressive Disorder[NCT05357040] | Phase 2 | 172 participants (Anticipated) | Interventional | 2021-06-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00430989)
Timeframe: 30 days
| Intervention | participants (Number) |
|---|---|
| Nitrous Oxide: 70% N2O (FiO2 0.3) | 15 |
| N2O Free Group (FiO2 0.3) | 19 |
(NCT00430989)
Timeframe: 30 Days Post Op
| Intervention | Days (Median) |
|---|---|
| Nitrous Oxide: 70% N2O (FiO2 0.3) | 6.1 |
| N2O Free Group (FiO2 0.3) | 6.1 |
(NCT00430989)
Timeframe: 30 days post op
| Intervention | participants (Number) |
|---|---|
| Nitrous Oxide: 70% N2O (FiO2 0.3) | 215 |
| N2O Free Group (FiO2 0.3) | 219 |
(NCT00430989)
Timeframe: 30 Days Post op
| Intervention | participants (Number) |
|---|---|
| N2O Group (FiO2 0.3) | 18 |
| N2O Free Group (FiO2 0.3) | 22 |
(NCT00430989)
Timeframe: 30 Days Post op
| Intervention | participants (Number) |
|---|---|
| Nitrous Oxide: 70% N2O (FiO2 0.3) | 26 |
| N2O Free Group (FiO2 0.3) | 19 |
(NCT00430989)
Timeframe: 30 days post op
| Intervention | participants (Number) |
|---|---|
| Nitrous Oxide: 70% N2O (FiO2 0.3) | 283 |
| N2O Free Group (FiO2 0.3) | 296 |
(NCT00430989)
Timeframe: 30 Days Post op
| Intervention | participants (Number) |
|---|---|
| Nitrous Oxide: 70% N2O (FiO2 0.3) | 321 |
| N2O Free Group (FiO2 0.3) | 311 |
1 review available for nitrous oxide and Cardiac Diseases
| Article | Year |
|---|---|
The anesthetic evaluation and management of the surgical patient with heart disease.
Topics: Aged; Anesthesia, Conduction; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Benzodia | 1983 |
3 trials available for nitrous oxide and Cardiac Diseases
23 other studies available for nitrous oxide and Cardiac Diseases
| Article | Year |
|---|---|
Impact of ENIGMA trials on nitrous oxide: a survey of Canadian anesthesiologists and residents.
Topics: Anesthesiologists; Anesthetics, Inhalation; Attitude of Health Personnel; Canada; Clinical Trials as | 2018 |
The use of nitrous oxide as an adjuvant for inhalation inductions with sevoflurane: a pro-con debate.
Topics: Adolescent; Anesthetics, Inhalation; Apoptosis; Child; Child, Preschool; Drug Interactions; Environm | 2013 |
1-1-12 one-step wash-in scheme for desflurane low flow anesthesia: performance without nitrous oxide.
Topics: Adolescent; Adult; Anesthesia, General; Blood Pressure; Desflurane; Female; Heart Diseases; Heart Ra | 2015 |
PERICAPILLARY GAS AND WATER DISTRIBUTION VOLUMES OF THE LUNG CALCULATED FROM MULTIPLE INDICATOR DILUTION CURVES.
Topics: Acetylene; Animals; Biomedical Research; Capillary Permeability; Dogs; Heart Diseases; Heart Failure | 1964 |
Anaesthesia and peripheral blood flow under general hypothermic perfusion.
Topics: Acidosis; Anesthesia, Inhalation; Body Temperature; Extracorporeal Circulation; Halothane; Heart Def | 1966 |
Effect of atrial systole on right ventricular stroke output in complete heart block.
Topics: Adult; Aged; Cardiac Catheterization; Cardiac Output; Female; Heart Atria; Heart Block; Heart Diseas | 1967 |
Nitrous oxide - are there any real contraindications?
Topics: Anesthesia, Dental; Anesthesia, Inhalation; Heart Diseases; Humans; Lung Diseases; Mental Disorders; | 1983 |
On-line systolic time intervals during anesthesia in patients with and without heart disease.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Blood Pressure; Female; Halothane; Hea | 1976 |
Cerebral oxygen consumption during sufentanil anesthesia: measurement by N2O uptake vs 133xenon clearance.
Topics: Anesthesia, Inhalation; Anesthetics; Brain; Cerebrovascular Circulation; Fentanyl; Heart Diseases; H | 1990 |
Nitrous oxide 1844-1990.
Topics: Anesthesia, Inhalation; Animals; Heart; Heart Diseases; History, 19th Century; History, 20th Century | 1990 |
[General anesthesia in patients with various pediatric cardiopathies].
Topics: Anesthesia, General; Anesthetics; Child; Dental Care for Disabled; Heart Diseases; Humans; Muscle Re | 1987 |
Gradual or abrupt nitrous oxide administration in a canine model of critical coronary stenosis induces regional myocardial dysfunction that is worsened by halothane.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Cardiomyopathies; Coronary Disease; Diastole; Dogs; Dru | 1988 |
[Combination anesthesia using methohexital in urologic patients posing medical risks].
Topics: Adult; Age Factors; Aged; Anesthesia, General; Benperidol; Carcinoma; Drug Synergism; Halothane; Hea | 1971 |
Anaesthesia for dentistry in children: a review of 101 surgical procedures.
Topics: Adolescent; Anesthesia, Dental; Anesthesia, General; Atropine; Auscultation; Blood Pressure Determin | 1970 |
Anesthesia for the patient with acquired and congenital heart disease.
Topics: Anesthesia; Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Aortic Valve Stenosis; Atropin | 1973 |
Cardiovascular effects of althesin in patients with cardiac pathology. Preliminary communication.
Topics: Adult; Anesthesia, General; Anesthetics; Blood Pressure; Diazepam; Electrocardiography; Extracorpore | 1972 |
Pulsus alternans as a complication of anesthesia.
Topics: Anesthesia, Inhalation; Anesthetics; Blood Pressure; Cyclopropanes; Electrocoagulation; Female; Halo | 1974 |
Phenoperidine in anaesthesia of respiratory cripples.
Topics: Abdomen; Adjuvants, Anesthesia; Analgesics; Anesthesia, General; Blood Pressure; Chlorpromazine; Cur | 1966 |
Heart disease and analgesia.
Topics: Anesthesia, Dental; Heart Diseases; Nitrous Oxide | 1969 |
Solubility of nitrous oxide in biologic fluid and myocardium.
Topics: Animals; Autopsy; Blood; Body Fluids; Cell Membrane; Chromatography, Gas; Dogs; Erythrocytes; Heart | 1970 |
Instantaneous lung capillary blood flow in patients with heart disease.
Topics: Adult; Aged; Blood Pressure; Capillaries; Cardiac Catheterization; Cardiac Output; Female; Heart Dis | 1970 |
[Anesthesia by means of GOBA in heart surgery].
Topics: Adult; Anesthesia, General; Ethyl Ethers; Heart Diseases; Humans; Male; Nitrous Oxide | 1967 |
Techniques for successful cardiopulmonary bypass in the calf.
Topics: Anesthesia, Inhalation; Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Surgical Procedures; | 1969 |