Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
| Trial | Phase | Enrollment | Study Type | Start Date | Status |
|---|
| Anaesthesia for Supratentorial Tumor Resection : a Double-blind Comparison of Target Plasma Concentration of Propofol-remifentanil and Sevoflurane-sufentanil[NCT00389883] | Phase 3 | 69 participants (Actual) | Interventional | 2006-11-30 | Completed |
| Anesthesiological Strategies in Elective Craniotomy: Randomized, Equivalence, Open Trial[NCT00741351] | Phase 3 | 411 participants (Actual) | Interventional | 2007-12-31 | Completed |
| The Effect of Furosemide Versus Placebo on Brain Relaxation and Incidence of Significant Intravascular Volume Depletion in Human Subjects Receiving Mannitol[NCT01054404] | | 23 participants (Actual) | Interventional | 2010-02-28 | Terminated (stopped due to Concern for volume depletion and electrolyte abnormalities in furosemide arm.) |
| Clinical Effectiveness of Hypertonic Sodium Lactate Infusion for Intraoperative Brain Relaxation in Patients Undergoing Scheduled Craniotomy for Supratentorial Brain Tumor Resection: Study Protocol of a Single Center Double-blind Randomized Controlled Pha[NCT04488874] | Phase 3 | 50 participants (Actual) | Interventional | 2020-09-29 | Completed |
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] |
"Rating of brain relaxation will be on a 4-point scale:~0 = brain very relaxed under dura, acceptable~= brain adequately relaxed under dura, acceptable~= brain slightly tense under dura, acceptable~= brain very tense under bulging dura, unacceptable" (NCT01054404)
Timeframe: just prior to dural opening for each subject
| Article | Year |
|---|
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.Anesthesiology, 1993, Volume: 78, Issue:6
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
Effect of anaesthesia on intracranial pressure in patients with space-occupying lesions.Lancet (London, England), 1969, Jan-11, Volume: 1, Issue:7585
Topics: Adolescent; Adult; Aged; Anesthesia, Endotracheal; Benperidol; Blood Pressure; Blood Volume; Brain A | 1969 |
| Article | Year |
|---|
Intraoperative airway obstruction due to dissection of a reinforced endotracheal tube in a prone patient.Journal of neurosurgical anesthesiology, 2011, Volume: 23, Issue:4
Topics: Adult; Airway Obstruction; Anesthesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Equipment Fa | 2011 |
Warm-water cooling.Acta anaesthesiologica Scandinavica. Supplementum, 1966, Volume: 23Topics: Adolescent; Adult; Aged; Body Temperature; Child; Chlorpromazine; Craniopharyngioma; Halothane; Hot | 1966 |
CBF and CMRO2 during continuous etomidate infusion supplemented with N2O and fentanyl in patients with supratentorial cerebral tumour. A dose-response study.Acta anaesthesiologica Scandinavica, 1985, Volume: 29, Issue:5
Topics: Adult; Aged; Anesthetics; Brain; Brain Neoplasms; Carbon Dioxide; Cerebrovascular Circulation; Dose- | 1985 |
Decrease in cerebrospinal fluid pressure following the pressure injection technique.Acta radiologica: diagnosis, 1972, Volume: 13, Issue:0
Topics: Adult; Aged; Brain Neoplasms; Cerebrospinal Fluid; Craniocerebral Trauma; Depression, Chemical; Fema | 1972 |
[Experiences in brain surgery with positive-negative pressure respiration anesthesia].Shujutsu. Operation, 1968, Volume: 22, Issue:5
Topics: Anesthesia, Inhalation; Brain Abscess; Brain Neoplasms; Child; Craniopharyngioma; Halothane; Humans; | 1968 |
Plasma cortisol responses during neurosurgical and abdominal operations.British journal of anaesthesia, 1971, Volume: 43, Issue:12
Topics: Abdomen; Adrenal Glands; Adult; Aged; Anesthesia, General; Betamethasone; Brain Neoplasms; Craniotom | 1971 |