nitrous oxide has been researched along with Anemia, Sickle Cell in 14 studies
Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, persisting neurological signs despite adequate treatment lately led to diagnose subacute combined medullar degeneration due to abnormal cobalamin (vitamin B12) metabolism induced by repeated use of nitrous oxide during painful episodes of sickle-cell disease." | 3.80 | [Vitamin B12 deficiency due to nitrous oxide use: unrecognized cause of combined spinal cord degeneration]. ( Cabral, D; Chaugny, C; Collin-Masson, H; De Beauchêne, M; Fagniez, O; Simon, J; Veyssier-Belot, C, 2014) |
| "Nalbuphine was the most commonly used opioid for moderate PVOE and morphine for severe PVOE." | 1.40 | How French paediatric emergency departments manage painful vaso-occlusive episodes in sickle cell disease patients. ( Carbajal, R; Courtois, E; Galeotti, C, 2014) |
| "As nitrous oxide is known to cause a neuropathy similar to that seen in pernicious anaemia, we postulate that nitrous oxide analgesia combined with low B12 levels was the cause of the marked neuropathy in these patients." | 1.30 | Sickle cell disease and nitrous oxide-induced neuropathy. ( Adepegba, T; Ogundipe, O; Pearson, MW; Slater, NG; Westerdale, N, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Hill, B | 1 |
| da Fonseca, MA | 1 |
| Hsu, LL | 1 |
| Neveu, J | 1 |
| Perelman, S | 1 |
| Suisse, G | 1 |
| Monpoux, F | 1 |
| Alrayyes, S | 1 |
| Compton, AA | 1 |
| Kawar, N | 1 |
| Delehaye, F | 1 |
| Villarbu, M | 1 |
| Salaun, V | 1 |
| Bracquemart, C | 1 |
| Goyer, I | 1 |
| Bodet, D | 1 |
| Chaugny, C | 1 |
| Simon, J | 1 |
| Collin-Masson, H | 1 |
| De Beauchêne, M | 1 |
| Cabral, D | 1 |
| Fagniez, O | 1 |
| Veyssier-Belot, C | 1 |
| Galeotti, C | 1 |
| Courtois, E | 1 |
| Carbajal, R | 2 |
| Faguer, S | 1 |
| Ruiz, J | 1 |
| Mari, A | 1 |
| Gérardin, M | 1 |
| Couec, ML | 1 |
| Grall-Bronnec, M | 1 |
| Feuillet, F | 1 |
| Wainstein, L | 1 |
| Rousselet, M | 1 |
| Pinot, ML | 1 |
| Perrouin, F | 1 |
| Bonnot, O | 1 |
| Drouineau, MH | 1 |
| Jolliet, P | 1 |
| Victorri-Vigneau, C | 1 |
| Brittain, JE | 1 |
| Parise, LV | 1 |
| Hubert, P | 1 |
| Treluyer, JM | 1 |
| Jouvet, P | 1 |
| Olivier-Martin, M | 1 |
| Ogundipe, O | 1 |
| Pearson, MW | 1 |
| Slater, NG | 1 |
| Adepegba, T | 1 |
| Westerdale, N | 1 |
| McGarry, P | 1 |
| Duncan, C | 1 |
| Edwards, R | 1 |
| Ffoulkes-Crabbe, DJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intranasal Sufentanil for Analgesia of Severe Sickle Cell Vaso-occlusive Pain Crisis in the Pediatric Emergency Department: a Double Blind Randomized Versus Placebo Controlled Trial[NCT06181695] | Phase 3 | 182 participants (Anticipated) | Interventional | 2024-05-02 | Not yet recruiting | ||
| PHEDRE Trial Protocol - Observational Study of the Prevalence of Problematic Use of Equimolar Mixture of Oxygen and Nitrous Oxide (EMONO) and Analgesics in the French Sickle-cell Disease Population[NCT02580565] | 1,004 participants (Actual) | Observational | 2015-09-25 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for nitrous oxide and Anemia, Sickle Cell
| Article | Year |
|---|---|
Oral health considerations for pediatric patients with sickle cell disease.
Topics: Anemia, Sickle Cell; Anesthetics, Inhalation; Anti-Bacterial Agents; Child; Conscious Sedation; Dent | 2018 |
Cytokines and plasma factors in sickle cell disease.
Topics: Analgesics, Non-Narcotic; Anemia, Sickle Cell; Angiogenesis Inducing Agents; Blood Platelets; Cytoki | 2007 |
12 other studies available for nitrous oxide and Anemia, Sickle Cell
| Article | Year |
|---|---|
Nitrous Oxide for Dental Procedures in Pediatric Patients with Sickle Cell Disease: A Pilot Study.
Topics: Anemia, Sickle Cell; Anesthesia, Dental; Anesthetics, Inhalation; Child; Conscious Sedation; Humans; | 2021 |
Severe hyperhomocysteinemia and peripheral neuropathy as side effects of nitrous oxide in two patients with sickle cell disease.
Topics: Adolescent; Anemia, Sickle Cell; Anesthetics, Inhalation; Female; Humans; Hyperhomocysteinemia; Male | 2019 |
Psychiatric manifestation and pancytopenia during a sickle cell vaso-occlusive crisis: An unusual etiology.
Topics: Adolescent; Anemia, Sickle Cell; Anesthetics, Inhalation; Arterial Occlusive Diseases; Female; Gait | 2019 |
[Vitamin B12 deficiency due to nitrous oxide use: unrecognized cause of combined spinal cord degeneration].
Topics: Analgesics, Non-Narcotic; Anemia, Sickle Cell; Drug-Related Side Effects and Adverse Reactions; Huma | 2014 |
How French paediatric emergency departments manage painful vaso-occlusive episodes in sickle cell disease patients.
Topics: Adolescent; Analgesics; Anemia, Sickle Cell; Child; Emergency Service, Hospital; France; Guideline A | 2014 |
Massive hyperhomocysteinaemia as a complication of nitrous oxide inhalation.
Topics: Acute Pain; Administration, Inhalation; Adult; Analgesics, Non-Narcotic; Anemia, Sickle Cell; Female | 2016 |
PHEDRE trial protocol - observational study of the prevalence of problematic use of Equimolar Mixture of Oxygen and Nitrous Oxide (EMONO) and analgesics in the French sickle-cell disease population.
Topics: Adolescent; Adult; Analgesics; Anemia, Sickle Cell; Child; Female; France; Humans; Male; Nitrous Oxi | 2015 |
Nitrous oxide and morphine in children with sickle cell crisis.
Topics: Administration, Inhalation; Analgesics, Non-Narcotic; Analgesics, Opioid; Anemia, Sickle Cell; Child | 1996 |
Sickle cell disease and nitrous oxide-induced neuropathy.
Topics: Adult; Analgesics, Non-Narcotic; Anemia, Sickle Cell; Female; Humans; Male; Nitrous Oxide; Periphera | 1999 |
Anesthetic risks in sickle cell trait.
Topics: Adolescent; Anemia, Sickle Cell; Anesthesia, General; Autopsy; Brain; Child; Child, Preschool; Death | 1973 |
Anaesthesia for caesarean section in haemoglobin SC disease complicated by eclampsia: a case report.
Topics: Adult; Anemia, Sickle Cell; Anesthesia, General; Anesthesia, Obstetrical; Cesarean Section; Chlormet | 1973 |
Haemoglobin levels and anesthesia in a Nigerian casualty department.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Anesthesia, General; Anesthesia, Local; Arteries; Carbon Dio | 1971 |