nitrous oxide has been researched along with Anemia, Megaloblastic in 24 studies
Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
Anemia, Megaloblastic: A disorder characterized by the presence of ANEMIA, abnormally large red blood cells (megalocytes or macrocytes), and MEGALOBLASTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Neutropenia following prolonged inhalation of nitrous oxide seems to be caused by a different mechanism, in which the cobalt in B12 is oxidised to the trivalent form by chemical reaction with nitrous oxide." | 4.76 | Anesthesia and the leucocyte. ( Nunn, JF, 1979) |
| "After exposure to nitrous oxide, an infant with unrecognized cobalamin deficiency developed neurologic deterioration and pancytopenia." | 3.70 | Acute neurologic decompensation in an infant with cobalamin deficiency exposed to nitrous oxide. ( Felmet, K; Hayflick, SJ; Robins, B; Tilford, D, 2000) |
| "As vitamin B12 deficiency is caused by malabsorption in the gastrointestinal tract, oral supplementation is insufficient." | 2.41 | [Subacute combined degeneration of the spinal cord: easy diagnosis, effective treatment]. ( Franke, CL; Jongen, JC; Koehler, PJ, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (75.00) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 5 (20.83) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burman, JF | 2 |
| Myles, PS | 1 |
| Leslie, K | 1 |
| Silbert, B | 1 |
| Paech, MJ | 1 |
| Peyton, P | 1 |
| Nunn, JF | 3 |
| Sharer, NM | 1 |
| Gorchein, A | 1 |
| Jones, JA | 1 |
| Wickramasinghe, SN | 1 |
| Amos, RJ | 1 |
| Amess, JA | 2 |
| Hinds, CJ | 1 |
| Mollin, DL | 2 |
| Blanco, G | 1 |
| Peters, HA | 1 |
| Rosenblatt, DS | 1 |
| Cooper, BA | 1 |
| Pottier, A | 1 |
| Lue-Shing, H | 1 |
| Matiaszuk, N | 1 |
| Grauer, K | 1 |
| Deacon, R | 4 |
| Lumb, MJ | 1 |
| Perry, J | 4 |
| Felmet, K | 1 |
| Robins, B | 1 |
| Tilford, D | 1 |
| Hayflick, SJ | 1 |
| Jongen, JC | 1 |
| Koehler, PJ | 1 |
| Franke, CL | 1 |
| van Geffen, GJ | 1 |
| de Boer, HD | 1 |
| Liem, T | 1 |
| Rees, GM | 1 |
| Nancekievill, DG | 1 |
| Beard, ME | 1 |
| Hamer, JW | 1 |
| Chanarin, I | 4 |
| Lumb, M | 3 |
| Haurani, FI | 1 |
| Muir, M | 1 |
| Lisiewicz, J | 1 |
| Gillman, MA | 1 |
| Berger, JJ | 1 |
| Modell, JH | 1 |
| Sypert, GW | 1 |
| Parry, TE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Nitrous Oxide In the Gas Mixture for Anaesthesia: a Randomised Controlled Trial[NCT00164047] | Phase 4 | 2,070 participants (Anticipated) | Interventional | 2003-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for nitrous oxide and Anemia, Megaloblastic
| Article | Year |
|---|---|
A review of the risks and benefits of nitrous oxide in current anaesthetic practice.
Topics: Anemia, Megaloblastic; Anesthesia; Anesthetics, Inhalation; Homocysteine; Humans; Hypoxia; Immunosup | 2004 |
Nitrous oxide, vitamin B12 deficiency and the methyl folate trap.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Megaloblastic; Animals; Humans; L | 1982 |
Vitamin B12, folate and nitrous oxide.
Topics: Anemia, Megaloblastic; Animals; Deoxyuridine; Folic Acid; Formates; Hematopoiesis; Humans; Methylati | 1982 |
[Subacute combined degeneration of the spinal cord: easy diagnosis, effective treatment].
Topics: Aged; Anemia, Megaloblastic; Anesthetics; Cervical Vertebrae; Female; Humans; Injections, Intramuscu | 2001 |
Anesthesia and the leucocyte.
Topics: Anemia, Megaloblastic; Anesthetics; Animals; Bone Marrow; Cell Movement; Chemotaxis, Leukocyte; Halo | 1979 |
Cobalamin and folate: recent developments.
Topics: Anemia, Megaloblastic; Female; Folic Acid; Humans; Methylation; Methylmalonic Acid; Nervous System D | 1992 |
Cobalamin-folate interrelations: a critical review.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Megaloblastic; Animals; Central N | 1985 |
1 trial available for nitrous oxide and Anemia, Megaloblastic
| Article | Year |
|---|---|
Megaloblastic haemopoiesis in patients receiving nitrous oxide.
Topics: Acute Disease; Anemia, Macrocytic; Anemia, Megaloblastic; Anesthesia, Inhalation; Bone Marrow; Cardi | 1978 |
16 other studies available for nitrous oxide and Anemia, Megaloblastic
| Article | Year |
|---|---|
Nitrous oxide and 5,10-methylenetetrahydrofolate reductase.
Topics: Anemia, Megaloblastic; Humans; Nitrous Oxide; Vitamin B 12 | 2003 |
Megaloblastic haemopoiesis after multiple short-term exposure to nitrous oxide.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Acute Disease; Adult; Anemia, Macrocytic; | 1982 |
Incidence and pathogenesis of acute megaloblastic bone-marrow change in patients receiving intensive care.
Topics: Adolescent; Adult; Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Anesthesia; Bone Marrow; Child; | 1982 |
Nitrous oxide and acute marrow failure.
Topics: Anemia, Megaloblastic; Bone Marrow; Hematopoiesis; Humans; Nitrous Oxide; Vitamin B 12 | 1982 |
Myeloneuropathy and macrocytosis associated with nitrous oxide abuse.
Topics: Adult; Anemia, Macrocytic; Anemia, Megaloblastic; Humans; Male; Nitrous Oxide; Peripheral Nervous Sy | 1983 |
Altered vitamin B12 metabolism in fibroblasts from a patient with megaloblastic anemia and homocystinuria due to a new defect in methionine biosynthesis.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Macrocytic; Anemia, Megaloblastic | 1984 |
Acute neurologic decompensation in an infant with cobalamin deficiency exposed to nitrous oxide.
Topics: Anemia, Megaloblastic; Anesthetics, Inhalation; Athetosis; Developmental Disabilities; Fatigue; Feve | 2000 |
[Subacute combined degeneration of the spinal cord due to vitamin B12 deficiency: easy diagnosis, effective therapy].
Topics: Anemia, Megaloblastic; Anesthetics; Humans; Malabsorption Syndromes; Mass Screening; Nitrous Oxide; | 2001 |
Nitrous oxide and the bone-marrow.
Topics: Anemia, Megaloblastic; Bone Marrow; Critical Care; Folic Acid Deficiency; Humans; Nitrous Oxide | 1978 |
Nitrous oxide and vitamin B12.
Topics: Anemia, Megaloblastic; Anesthesia, Inhalation; Animals; Humans; Nitrous Oxide; Rats; Time Factors; V | 1978 |
The effects of free radicals on cobalamin and iron.
Topics: Anemia, Megaloblastic; Free Radicals; Humans; Iron; Nitrous Oxide; Vitamin B 12 | 1989 |
[Megaloblastic anemia and occupational exposure].
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Arsenic; Benzene; Chemical Industry; Humans; Nitrous Oxid | 1988 |
Folinic acid prevents megaloblastic changes associated with nitrous oxide.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Humans; Leucovorin; Nitrous Oxide; Time Factors | 1988 |
Megaloblastic anemia and brief exposure to nitrous oxide--a causal relationship.
Topics: Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Female; Humans; Nitrous Oxide; Vitamin B 12 | 1988 |
Cobalamin-folate interrelations.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Animals; Enzyme Activation; Folic Acid; Humans; Isomerase | 1987 |
Role of folate dependent transformylases in synthesis of purine in bone marrow of man and in bone marrow and liver of rats.
Topics: Acyltransferases; Adenosine; Anemia, Megaloblastic; Animals; Bone Marrow; Deoxyadenosines; Humans; H | 1985 |