Page last updated: 2024-10-19

nitrous oxide and Amnesia-Memory Loss

nitrous oxide has been researched along with Amnesia-Memory Loss in 16 studies

Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.

Research Excerpts

ExcerptRelevanceReference
"The nitrous oxide was terminated at completion of the aspiration."1.28[Amnesic effect of nitrous oxide in gradual general anesthesia]. ( Bachelet, Y; Berlemont, D; Milhaud, A; Mouquet, W, 1989)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199015 (93.75)18.7374
1990's0 (0.00)18.2507
2000's1 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alkire, MT1
Gorski, LA1
Stanley, TH1
Reddy, P1
Gilmore, S1
Bennett, G1
Dich-Nielsen, J1
Holasek, J1
De Castro, J1
Parmentier, P1
Cormack, RS1
Tunstall, ME1
Mouquet, W1
Milhaud, A1
Berlemont, D1
Bachelet, Y1
Levy, WJ1
Stovner, J1
Vangen, O1
Porter, AL1
Wong, KC1
Martin, WE1
Hornbein, TF1
Freund, FG1
Everett, J1
Hunter, AR1
Isaac, M1
Pandit, SK1
Dundee, JW1
Galway, JE1
Eisenberg, L1
Kwan, AM1
Smith, BE1
Moya, F1
Gruber, RP1
Reed, DR1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Neurotoxic Effect of Sevoflurane-Based Anaesthesia Guided by Significant Short-Term Olfactory Identification Impairment in Old Age[NCT03726580]600 participants (Actual)Observational [Patient Registry]2017-03-01Completed
Does a Single Intravenous Dose of Ketamine Reduce the Need for Supplemental Opioids in Post-Cesarean Section Patients?[NCT00486902]188 participants (Actual)Interventional2006-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Cumulative Hydrocodone/Acetaminophen for Supplemental Analgesia to Treat Breakthrough Pain

Cumulative hydrocodone/acetaminophen for supplemental analgesia to treat breakthrough pain for 72 hours following cesarean delivery (NCT00486902)
Timeframe: 72 hours

Interventiontablets (Median)
Ketamine10
Placebo9

Disturbing Dreams

Number of subject reporting disturbing dreams at 72 hours post cesarean delivery (NCT00486902)
Timeframe: 72 hours

Interventionparticipants (Number)
Ketamine0
Placebo0

Number of Subjects Requiring Supplemental Analgesia in the First 24 Hours Following Cesarean Delivery

Request for oral hydrocodone/acetaminophen for pain not controlled by around the clock non-steroidal antiflammatory drugs in the first 24 hours following cesarean delivery. (NCT00486902)
Timeframe: 24 hours

Interventionparticipants (Number)
Ketamine64
Placebo66

Pain Score (0-10) at 2 Weeks Following Cesarean Delivery

Numeric rating for pain score (0 to 10) reported at 2 weeks following cesarean delivery. Zero is no pain and 10 is worst pain imaginable. (NCT00486902)
Timeframe: 2 weeks

InterventionScores on a scale (Median)
Ketamine2
Placebo2.6

Postoperative Nausea

Number of subjects reporting nausea in first 24 hours following cesarean delivery (NCT00486902)
Timeframe: 24 hours

Interventionparticipants (Number)
Ketamine27
Placebo30

Postoperative Vomiting

Number of subjects that vomited in the first 24 hours following cesarean delivery (NCT00486902)
Timeframe: 24 hours

Interventionparticipants (Number)
Ketamine13
Placebo13

Postperative Pruritus

Number of subjects with pruritus in the first 24 hours following cesarean delivery (NCT00486902)
Timeframe: 24 hours

Interventionparticipants (Number)
Ketamine12
Placebo19

Verbal Pain Scores (0 to 10) at First Analgesia Request

Numeric rating of pain scores (NRS) scale (0 to 10) at time of supplemental analgesia request. Zero is no pain and 10 is worst pain imaginable. (NCT00486902)
Timeframe: 24 hours

InterventionScores on a scale (Median)
Ketamine3
Placebo4

Reviews

1 review available for nitrous oxide and Amnesia-Memory Loss

ArticleYear
An analytical review of the effects of non-hydrogen-bonding anesthetics on memory processing.
    Behavioral biology, 1972, Volume: 7, Issue:3

    Topics: Age Factors; Amnesia; Anesthesia, Inhalation; Anesthetics; Animals; Behavior, Animal; Carbon Dioxide

1972

Trials

2 trials available for nitrous oxide and Amnesia-Memory Loss

ArticleYear
Awareness during surgery--a new approach.
    British journal of anaesthesia, 1979, Volume: 51, Issue:11

    Topics: Adult; Amnesia; Anesthesia; Anti-Anxiety Agents; Consciousness; Dose-Response Relationship, Drug; Fe

1979
The reduction of amnesic wakefulness during caesarean section.
    Anaesthesia, 1979, Volume: 34, Issue:4

    Topics: Amnesia; Anesthesia, Obstetrical; Cesarean Section; Female; Halothane; Humans; Nitrous Oxide; Pregna

1979

Other Studies

13 other studies available for nitrous oxide and Amnesia-Memory Loss

ArticleYear
Relative amnesic potency of five inhalational anesthetics follows the Meyer-Overton rule.
    Anesthesiology, 2004, Volume: 101, Issue:2

    Topics: Amnesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Avoidance Learning; Behavior, Ani

2004
The cardiovascular effects of high-dose butorphanol-nitrous oxide anaesthesia before and during operation.
    Canadian Anaesthetists' Society journal, 1983, Volume: 30, Issue:4

    Topics: Adjuvants, Anesthesia; Amnesia; Analgesia; Anesthesia, General; Blood Pressure; Butorphanol; Cardiac

1983
Ketamine as induction agent for caesarean section.
    Acta anaesthesiologica Scandinavica, 1982, Volume: 26, Issue:2

    Topics: Amnesia; Anesthesia, General; Anesthesia, Obstetrical; Apgar Score; Cesarean Section; Diazepam; Drea

1982
[Choice of a potentiator of analgesics].
    Annales de l'anesthesiologie francaise, 1976, Volume: 17, Issue:10

    Topics: Amnesia; Analgesics, Opioid; Anesthesia; Anesthetics; Autonomic Nerve Block; Barbiturates; Diazepam;

1976
[Amnesic effect of nitrous oxide in gradual general anesthesia].
    Cahiers d'anesthesiologie, 1989, Volume: 37, Issue:3

    Topics: Abortion, Induced; Adolescent; Adult; Amnesia; Anesthesia, Inhalation; Anesthesia, Obstetrical; Fema

1989
Power spectrum correlates of changes in consciousness during anesthetic induction with enflurane.
    Anesthesiology, 1986, Volume: 64, Issue:6

    Topics: Amnesia; Anesthesia; Consciousness; Electroencephalography; Enflurane; Humans; Male; Nitrous Oxide;

1986
Diazepam compared to thiopentone as induction agent for caesarean sections.
    Acta anaesthesiologica Scandinavica, 1974, Volume: 18, Issue:4

    Topics: Amnesia; Anesthesia, Intravenous; Anesthesia, Obstetrical; Apgar Score; Atropine; Cesarean Section;

1974
The cardiovascular effects of morphine sulfate with oxygen and with nitrous oxide in man.
    Anesthesiology, 1973, Volume: 38, Issue:6

    Topics: Acid-Base Equilibrium; Adult; Amnesia; Anesthesia, Intravenous; Blood Flow Velocity; Blood Glucose;

1973
Thiopentone supplemented anaesthesia for neurosurgery.
    British journal of anaesthesia, 1972, Volume: 44, Issue:5

    Topics: Adult; Amnesia; Anesthesia, General; Brain; Female; Humans; Immobilization; Intracranial Pressure; M

1972
Intravenous ethanol anaesthesia. A study of sequelae and their implications.
    Acta anaesthesiologica Scandinavica, 1971, Volume: 15, Issue:3

    Topics: Alcohol Deterrents; Alcoholic Intoxication; Amnesia; Anesthesia, Intravenous; Atropine; Barbiturates

1971
Neuroleptanaesthesia with diazepam-morphine in poor-risk surgical patients.
    Canadian Anaesthetists' Society journal, 1971, Volume: 18, Issue:4

    Topics: Adult; Aged; Amnesia; Atropine; Carbon Dioxide; Diazepam; Female; Humans; Injections, Intramuscular;

1971
Inhalational analgesia with methoxyflurane for vaginal delivery.
    Southern medical journal, 1968, Volume: 61, Issue:4

    Topics: Acid-Base Equilibrium; Amnesia; Anesthesia, Inhalation; Anesthesia, Obstetrical; Blood Gas Analysis;

1968
Postoperative anterograde amnesia.
    British journal of anaesthesia, 1968, Volume: 40, Issue:11

    Topics: Adult; Amnesia; Anesthesia, General; Atropine; Female; Halothane; Humans; Male; Meperidine; Nitrous

1968