nitrous oxide has been researched along with Alcohol Abuse in 43 studies
Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Elderly patients with alcoholism often require surgery and receive nitrous oxide (N2O) as a component of their anesthetic." | 7.68 | Aging, chronic administration of ethanol, and acute exposure to nitrous oxide: effects on vitamin B12 and folate status in rats. ( Everman, BW; Koblin, DD, 1992) |
| "Elderly patients with alcoholism often require surgery and receive nitrous oxide (N2O) as a component of their anesthetic." | 3.68 | Aging, chronic administration of ethanol, and acute exposure to nitrous oxide: effects on vitamin B12 and folate status in rats. ( Everman, BW; Koblin, DD, 1992) |
| "Nitrous oxide gas (N2O) has been proposed to be effective in the treatment of the alcohol withdrawal syndrome (AWS)." | 2.70 | Long-term effects of and physiological responses to nitrous oxide gas treatment during alcohol withdrawal: a double-blind, placebo-controlled trial. ( Alho, H; Methuen, T; Paloheimo, M; Roine, R; Salaspuro, M; Seppä, K; Strid, N; Tiainen, J, 2002) |
| " The outcomes considered were alcohol withdrawal seizures, adverse events and dropouts." | 2.47 | Efficacy and safety of pharmacological interventions for the treatment of the Alcohol Withdrawal Syndrome. ( Amato, L; Davoli, M; Minozzi, S, 2011) |
| "One of the most severe consequences of alcohol dependence is the withdrawal syndrome, for which benzodiazepines are the most popular current treatment." | 2.44 | Psychotropic analgesic nitrous oxide for alcoholic withdrawal states. ( Gillman, MA; Lichtigfeld, FJ; Young, TN, 2007) |
| "A vitamin B12 deficiency is unusual in pregnant women who consume a normal, varied diet." | 2.37 | Clinical chemistry of vitamin B12. ( Davis, RE, 1985) |
| "Nitrous oxide (N2O) has been reported to reduce post-withdrawal craving in alcoholic humans, aiding in their continued abstinence." | 1.33 | Nitrous oxide acutely suppresses ethanol consumption in HAD and P rats. ( Kebabian, CE; Kosobud, AE; Rebec, GV, 2006) |
| "Chemical dependence is a devastating disease that, unless some form of intervention and treatment takes place, will ultimately destroy a person's life." | 1.29 | The Texas Dental Peer Assistance Program and the impaired dental professional. ( Jessee, SA, 1993) |
| "The chronic administration of ethanol or brief exposure to nitrous oxide (N2O) decreases the activity of hepatic methionine synthase and disrupts normal metabolic processes that require folate and vitamin B12." | 1.28 | Vitamin B12 and folate status in rats after chronic administration of ethanol and acute exposure to nitrous oxide. ( Everman, BW; Koblin, DD, 1991) |
| " The dose-response curve of the chronic ethanol-exposed group was shifted to the right of that of the control mice." | 1.28 | Influence of chronic ethanol exposure on nitrous oxide analgesia in mice. ( Henry, RJ; Ishii, MM; Quock, RM, 1990) |
| "Thiopental (3 mg/kg/min) was given for induction." | 1.26 | The need for halothane supplementation of N2O-O2-relaxant anaesthesia in chronic alcoholics. ( Tammisto, T; Tigerstedt, I, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (23.26) | 18.7374 |
| 1990's | 15 (34.88) | 18.2507 |
| 2000's | 12 (27.91) | 29.6817 |
| 2010's | 5 (11.63) | 24.3611 |
| 2020's | 1 (2.33) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen, L | 3 |
| Duroy, D | 3 |
| Perozziello, A | 3 |
| Sasportes, A | 3 |
| Lejoyeux, M | 3 |
| Geoffroy, PA | 3 |
| Christen, AG | 1 |
| Christen, JA | 1 |
| Vengeliene, V | 1 |
| Bessiere, B | 1 |
| Pype, J | 1 |
| Spanagel, R | 1 |
| Safdieh, JE | 1 |
| Chin, J | 1 |
| Forzani, B | 1 |
| Chowdhury, N | 1 |
| Lombardo, S | 1 |
| Rizzo, JR | 1 |
| Ragucci, M | 1 |
| Krystal, JH | 1 |
| Petrakis, IL | 1 |
| O'Malley, S | 1 |
| Krishnan-Sarin, S | 1 |
| Pearlson, G | 1 |
| Yoon, G | 1 |
| Gillman, MA | 11 |
| Amato, L | 1 |
| Minozzi, S | 1 |
| Davoli, M | 1 |
| Alho, H | 1 |
| Methuen, T | 1 |
| Paloheimo, M | 1 |
| Strid, N | 1 |
| Seppä, K | 1 |
| Tiainen, J | 1 |
| Salaspuro, M | 1 |
| Roine, R | 1 |
| Lichtigfeld, FJ | 8 |
| Diamond, I | 1 |
| Gillman, M | 1 |
| Lichtigfeld, F | 1 |
| Chick, J | 1 |
| Franck, J | 1 |
| Kosobud, AE | 1 |
| Kebabian, CE | 1 |
| Rebec, GV | 1 |
| Young, TN | 1 |
| Gilmann, MA | 1 |
| Lindenbaum, J | 1 |
| Ficarra, BJ | 1 |
| Daynes, G | 1 |
| Ojutkangas, R | 1 |
| Brimacombe, J | 1 |
| Jessee, SA | 1 |
| Belknap, JK | 1 |
| Metten, P | 1 |
| Helms, ML | 1 |
| O'Toole, LA | 1 |
| Angeli-Gade, S | 1 |
| Crabbe, JC | 1 |
| Phillips, TJ | 1 |
| Tammisto, T | 4 |
| Tigerstedt, I | 2 |
| Myles, MJ | 1 |
| Everman, BW | 2 |
| Koblin, DD | 2 |
| Henry, RJ | 1 |
| Ishii, MM | 1 |
| Quock, RM | 1 |
| Davis, RE | 1 |
| Takki, S | 2 |
| Meyer, JS | 1 |
| Gotoh, F | 1 |
| Akiyama, M | 1 |
| Yoshitake, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective Assessment of Valproate on Ethanol Withdrawal[NCT03235531] | Phase 4 | 210 participants (Anticipated) | Interventional | 2017-07-11 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for nitrous oxide and Alcohol Abuse
| Article | Year |
|---|---|
Dental education in the prevention and treatment of substance use disorders.
Topics: Alcoholism; Anesthetics, Inhalation; Clinical Competence; Curriculum; Education, Dental; Humanism; H | 2002 |
Efficacy and safety of pharmacological interventions for the treatment of the Alcohol Withdrawal Syndrome.
Topics: Alcohol Withdrawal Seizures; Alcoholism; Anticonvulsants; Baclofen; Benzodiazepines; Ethanol; Humans | 2011 |
Psychotropic analgesic nitrous oxide for alcoholic withdrawal states.
Topics: Alcoholic Beverages; Alcoholism; Analgesics, Non-Narcotic; Humans; Nitrous Oxide; Randomized Control | 2007 |
Drugs and vitamin B12 and folate metabolism.
Topics: Alcoholism; Animals; Anticonvulsants; Ascorbic Acid; Contraceptives, Oral; Folic Acid; Folic Acid An | 1983 |
Psychotropic analgesic nitrous oxide and neurotransmitter mechanisms involved in the alcohol withdrawal state.
Topics: Acetylcholine; Alcoholism; Epinephrine; Ethanol; gamma-Aminobutyric Acid; Glutamates; Humans; Neurot | 1994 |
Quantitative trait loci (QTL) applications to substances of abuse: physical dependence studies with nitrous oxide and ethanol in BXD mice.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Chromosome Mapping; Genetic Markers; Mice; Mice, I | 1993 |
Clinical chemistry of vitamin B12.
Topics: Absorption; Adult; Alcoholism; Anemia, Pernicious; Ascorbic Acid; Autoantibodies; Biguanides; Biolog | 1985 |
3 trials available for nitrous oxide and Alcohol Abuse
| Article | Year |
|---|---|
Long-term effects of and physiological responses to nitrous oxide gas treatment during alcohol withdrawal: a double-blind, placebo-controlled trial.
Topics: Alcoholism; Behavior, Addictive; Chi-Square Distribution; Double-Blind Method; Humans; Linear Models | 2002 |
Placebo and analgesic nitrous oxide for treatment of the alcohol withdrawal state.
Topics: Administration, Inhalation; Adult; Alcohol Withdrawal Delirium; Alcoholism; Carbon Dioxide; Double-B | 1991 |
Opioid effects of analgesic (subanesthetic) nitrous oxide on the alcohol withdrawal state.
Topics: Alcoholism; Analgesics; Double-Blind Method; Humans; Nitrous Oxide; Placebos; Substance Withdrawal S | 1991 |
33 other studies available for nitrous oxide and Alcohol Abuse
| Article | Year |
|---|---|
A cross-sectional study: Nitrous oxide abuse in Parisian medical students.
Topics: Alcoholism; Behavior, Addictive; Cross-Sectional Studies; Humans; Male; Nitrous Oxide; Students, Med | 2023 |
A cross-sectional study: Nitrous oxide abuse in Parisian medical students.
Topics: Alcoholism; Behavior, Addictive; Cross-Sectional Studies; Humans; Male; Nitrous Oxide; Students, Med | 2023 |
A cross-sectional study: Nitrous oxide abuse in Parisian medical students.
Topics: Alcoholism; Behavior, Addictive; Cross-Sectional Studies; Humans; Male; Nitrous Oxide; Students, Med | 2023 |
A cross-sectional study: Nitrous oxide abuse in Parisian medical students.
Topics: Alcoholism; Behavior, Addictive; Cross-Sectional Studies; Humans; Male; Nitrous Oxide; Students, Med | 2023 |
A cross-sectional study: Nitrous oxide abuse in Parisian medical students.
Topics: Alcoholism; Behavior, Addictive; Cross-Sectional Studies; Humans; Male; Nitrous Oxide; Students, Med | 2023 |
A cross-sectional study: Nitrous oxide abuse in Parisian medical students.
Topics: Alcoholism; Behavior, Addictive; Cross-Sectional Studies; Humans; Male; Nitrous Oxide; Students, Med | 2023 |
A cross-sectional study: Nitrous oxide abuse in Parisian medical students.
Topics: Alcoholism; Behavior, Addictive; Cross-Sectional Studies; Humans; Male; Nitrous Oxide; Students, Med | 2023 |
A cross-sectional study: Nitrous oxide abuse in Parisian medical students.
Topics: Alcoholism; Behavior, Addictive; Cross-Sectional Studies; Humans; Male; Nitrous Oxide; Students, Med | 2023 |
A cross-sectional study: Nitrous oxide abuse in Parisian medical students.
Topics: Alcoholism; Behavior, Addictive; Cross-Sectional Studies; Humans; Male; Nitrous Oxide; Students, Med | 2023 |
The effects of xenon and nitrous oxide gases on alcohol relapse.
Topics: Alcoholism; Anesthetics, Inhalation; Animals; Atmosphere Exposure Chambers; Conditioning, Operant; C | 2014 |
Patient management problem.
Topics: Adenocarcinoma; Aged; Alcoholism; Anesthetics, Inhalation; Bariatric Surgery; Diabetes Mellitus, Typ | 2014 |
Rehabilitation essential in the recovery of multifactorial subacute combined degeneration.
Topics: Adult; Alcoholism; Anemia, Pernicious; Humans; Male; Nitrous Oxide; Subacute Combined Degeneration; | 2015 |
NMDA Glutamate Receptor Antagonism and the Heritable Risk for Alcoholism: New Insights from a Study of Nitrous Oxide.
Topics: Alcoholism; Glutamic Acid; Humans; N-Methylaspartate; Nitrous Oxide; Receptors, N-Methyl-D-Aspartate | 2017 |
Psychotropic analgesic nitrous oxide for alcohol withdrawal.
Topics: Alcoholism; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Clinical Trials as Topic; Ethanol; Hu | 2008 |
Correct use of analgesic nitrous oxide for the alcohol withdrawal state is essential.
Topics: Alcoholism; Anesthetics, Inhalation; Ethanol; Humans; Nitrous Oxide; Substance Withdrawal Syndrome | 2004 |
Further comments on the effects of nitrous oxide treatment on alcohol withdrawal.
Topics: Alcoholism; Humans; Nitrous Oxide; Randomized Controlled Trials as Topic; Substance Withdrawal Syndr | 2004 |
Long-term effects of and physiological responses to nitrous oxide gas treatment during alcohol withdrawal: a double-blind, placebo-controlled trial.
Topics: Alcoholism; Double-Blind Method; Humans; Nitrous Oxide; Randomized Controlled Trials as Topic; Subst | 2004 |
An incorrect technique guarantees failure.
Topics: Alcoholism; Double-Blind Method; Humans; Nitrous Oxide; Randomized Controlled Trials as Topic; Resea | 2004 |
The nitrous oxide study: two points (expert response to Gillman/Alho letters to the editor).
Topics: Alcoholism; Double-Blind Method; Humans; Nitrous Oxide; Randomized Controlled Trials as Topic; Subst | 2004 |
Expert response to Gillman/Alho.
Topics: Alcoholism; Double-Blind Method; Humans; Nitrous Oxide; Randomized Controlled Trials as Topic; Subst | 2004 |
You are not alone.
Topics: Alcoholism; Anesthetics, Inhalation; Dentists; Humans; Nitrous Oxide; Professional Impairment; Subst | 2005 |
Nitrous oxide acutely suppresses ethanol consumption in HAD and P rats.
Topics: Alcohol Drinking; Alcoholism; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Behavior, Ani | 2006 |
Nitrous oxide and treatment of withdrawal symptoms.
Topics: Alcoholism; Endorphins; Humans; Nitrous Oxide; Opioid-Related Disorders; Substance Withdrawal Syndro | 1980 |
Toxicologic states treated in an Emergency Department.
Topics: Alcoholism; Camphor; Emergency Service, Hospital; Ethylene Oxide; Humans; Illicit Drugs; Nitrous Oxi | 1980 |
Analgesic nitrous oxide for addictive withdrawal.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Humans; Nitrous Oxide | 1994 |
Analgesic nitrous oxide for addictive withdrawal.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Humans; Nitrous Oxide | 1994 |
Psychotropic analgesic nitrous oxide as an investigative diagnostic and therapeutic tool.
Topics: Alcoholism; Central Nervous System; Drugs, Investigational; Humans; Inactivation, Metabolic; Nitrous | 1994 |
Psychotropic analgesic nitrous oxide prevents craving after withdrawal for alcohol, cannabis and tobacco.
Topics: Adolescent; Adult; Alcoholism; Ethanol; Female; Humans; Male; Marijuana Abuse; Middle Aged; Nitrous | 1994 |
Psychotropic analgesic nitrous oxide for treating alcohol withdrawal in an outpatient setting.
Topics: Adult; Aged; Alcoholism; Ambulatory Care; Ethanol; Female; Humans; Male; Middle Aged; Nitrous Oxide; | 1994 |
An extreme case of resistance to anaesthetic agents.
Topics: Adult; Alcoholism; Anesthesia, Inhalation; Anesthesia, Intravenous; Drug Resistance; Fentanyl; Halot | 1994 |
The Texas Dental Peer Assistance Program and the impaired dental professional.
Topics: Alcoholism; Dentists; Humans; Licensure, Dental; Nitrous Oxide; Peer Group; Professional Impairment; | 1993 |
The need for halothane supplementation of N2O-O2-relaxant anaesthesia in chronic alcoholics.
Topics: Alcoholism; Anesthesia, Inhalation; Biliary Tract Surgical Procedures; Blood Pressure; Digestive Sys | 1977 |
The need for fentanyl supplementation of N2O-O2 relaxant anaesthesia in chronic alcoholics.
Topics: Adult; Aged; Alcoholism; Anesthesia, Inhalation; Biliary Tract Surgical Procedures; Drug Resistance; | 1977 |
Managing alcohol withdrawal states with oxygen and nitrous oxide.
Topics: Alcoholism; Humans; Nitrous Oxide; Oxygen Inhalation Therapy; Substance Withdrawal Syndrome | 1992 |
Aging, chronic administration of ethanol, and acute exposure to nitrous oxide: effects on vitamin B12 and folate status in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aging; Alcoholism; Animals; Disease Model | 1992 |
Vitamin B12 and folate status in rats after chronic administration of ethanol and acute exposure to nitrous oxide.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alcoholism; Animals; Folic Acid; Formates | 1991 |
Influence of chronic ethanol exposure on nitrous oxide analgesia in mice.
Topics: Alcoholism; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Ethanol; Male; Mice; Nitrous | 1990 |
Chemical dependency: the road to recovery.
Topics: Adult; Alcoholism; American Dental Association; Child; Cocaine; Denial, Psychological; Dentists; Fam | 1987 |
The effect of operative stress on plasma catecholamine levels in chronic alcoholics.
Topics: Adjuvants, Anesthesia; Adult; Alcohol Drinking; Alcoholism; Anesthesia, General; Bis-Trimethylammoni | 1974 |
Nitrous oxide-oxygen-relaxant anaesthesia in alcoholics: a retrospective study.
Topics: Adult; Aged; Alcoholism; Anesthesia, General; Biliary Tract Diseases; Blood Pressure; Droperidol; Fe | 1973 |
Automatic recording of cerebral blood flow by nitrous oxide inhalation without blood loss.
Topics: Adolescent; Adult; Aged; Alcoholism; Animals; Anxiety Disorders; Blood Flow Velocity; Carbon Dioxide | 1967 |