nitrous oxide has been researched along with Aging in 61 studies
Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We asked whether the sympathomimetic effect of nitrous oxide (N2O) predisposed patients receiving N2O to arrhythmias in response to epinephrine administration." | 9.06 | Nitrous oxide and epinephrine-induced arrhythmias. ( Donegan, JH; Fouts, KE; Lampe, GH; Litt, LL; Rampil, IJ; Rose, BM; Rupp, SM; Wauk, LZ; Whitendale, P; Wilson, CB, 1990) |
| "Elderly patients with alcoholism often require surgery and receive nitrous oxide (N2O) as a component of their anesthetic." | 7.68 | Aging, chronic administration of ethanol, and acute exposure to nitrous oxide: effects on vitamin B12 and folate status in rats. ( Everman, BW; Koblin, DD, 1992) |
| "The cardiovascular effects of halothane anesthesia in a mixture of nitrous oxide and oxygen were studied on piglets 7 hr to 25 days of age." | 7.65 | Age-dependent cardiovascular effects of halothane anesthesia in neonatal pigs. ( Crane, L; Gootman, N; Gootman, PM, 1975) |
| "We asked whether the sympathomimetic effect of nitrous oxide (N2O) predisposed patients receiving N2O to arrhythmias in response to epinephrine administration." | 5.06 | Nitrous oxide and epinephrine-induced arrhythmias. ( Donegan, JH; Fouts, KE; Lampe, GH; Litt, LL; Rampil, IJ; Rose, BM; Rupp, SM; Wauk, LZ; Whitendale, P; Wilson, CB, 1990) |
| "Elderly patients with alcoholism often require surgery and receive nitrous oxide (N2O) as a component of their anesthetic." | 3.68 | Aging, chronic administration of ethanol, and acute exposure to nitrous oxide: effects on vitamin B12 and folate status in rats. ( Everman, BW; Koblin, DD, 1992) |
| "The effects of age on the pharmacokinetics and pharmacodynamics of vecuronium in eight elderly patients aged 72-86 yr and eight younger adults aged 26-48 yr undergoing elective surgical procedures under nitrous oxide-fentanyl anesthesia were studied." | 3.68 | Distribution, elimination, and action of vecuronium in the elderly. ( Diaz, J; Lien, CA; Matteo, RS; Ornstein, E; Schwartz, AE, 1991) |
| "To evaluate the effect of aging on the distribution, clearance, and neuromuscular junction sensitivity to atracurium, the authors determined the pharmacokinetics and pharmacodynamics of atracurium in five healthy elderly subjects (74-76 yr) during halothane-nitrous oxide anesthesia and compared these values to those obtained previously in five healthy young adults (22-44 yr)." | 3.68 | Pharmacokinetics and pharmacodynamics of atracurium in the elderly. ( Caldwell, JE; Canfell, PC; Fahey, MR; Fisher, DM; Heier, T; Kitts, JB; Miller, RD; Spellman, MJ, 1990) |
| "Vecuronium kinetics and dynamics were determined in five infants (3 to 11 months old) and five children (1 to 5 years old) during anesthesia with 70% nitrous oxide and 0." | 3.67 | Vecuronium kinetics and dynamics in anesthetized infants and children. ( Castagnoli, K; Fisher, DM; Miller, RD, 1985) |
| "Effects of age on the pharmacodynamics of alfentanil, as a supplement to nitrous oxide anesthesia, were studied in younger (31-52 years; n = 14) and older (56-86 years; n = 14) women undergoing curative surgery for primary breast cancer." | 3.67 | Age has no effect on the pharmacodynamics of alfentanil. ( Bovill, JG; Burm, AG; Hennis, PJ; Lemmens, HJ, 1988) |
| "The cardiovascular effects of halothane anesthesia in a mixture of nitrous oxide and oxygen were studied on piglets 7 hr to 25 days of age." | 3.65 | Age-dependent cardiovascular effects of halothane anesthesia in neonatal pigs. ( Crane, L; Gootman, N; Gootman, PM, 1975) |
| "Mivacurium was infused, targeting 90% twitch depression." | 2.69 | The pharmacokinetics and steady state pharmacodynamics of mivacurium in children. ( Brown, R; Fisher, DM; Lau, M; Luks, AM; Markakis, DA; Sharma, ML, 1998) |
| "The mivacurium infusion rate was adjusted to maintain single twitch depression at 95 +/- 4% of control." | 2.68 | Prolonged mivacurium infusion in young and elderly adults. ( Chakravorti, S; Cook, DR; Denman, W; Goudsouzian, N; Schwartz, A; Yang, HS, 1997) |
| "Nitrous oxide is a commonly used anesthetic that inhibits the activity of methionine synthase, an enzyme involved in methylation reactions and DNA synthesis and repair." | 1.34 | Nitrous oxide decreases cortical methionine synthase transiently but produces lasting memory impairment in aged rats. ( Baxter, MG; Crosby, G; Culley, DJ; Deth, RC; Raghavan, SV; Waly, M; Yukhananov, R, 2007) |
| "The effects of age on the pharmacokinetic and pharmacodynamic responses to rocuronium (Org 9426) were studied in 20 elderly (> 70 yr) and 20 younger control patients (< 60 yr) during N2O/O2, fentanyl anesthesia." | 1.29 | Pharmacokinetics and pharmacodynamics of rocuronium (Org 9426) in elderly surgical patients. ( Matteo, RS; Ornstein, E; Ostapkovich, N; Schwartz, AE; Stone, JG, 1993) |
| "The dose recommendations for atropine in anesthetized children vary, and the dose-response for heart rate has not been defined." | 1.28 | Dose-response for atropine and heart rate in infants and children anesthetized with halothane and nitrous oxide. ( Brown, MP; Palmisano, BW; Setlock, MA; Siker, D; Tripuraneni, R, 1991) |
| "Desflurane appears to be a mild airway irritant but was well tolerated by all patients." | 1.28 | Clinical characteristics of desflurane in surgical patients: minimum alveolar concentration. ( Damask, MC; Eger, EI; Lockhart, SH; Peterson, N; Rampil, IJ; Weiskopf, RB; Yasuda, N; Zwass, MS, 1991) |
| "Bupivacaine was infused at a constant rate while the pigs' ECGs and EEGs were recorded." | 1.28 | Bupivacaine toxicity in young pigs is age-dependent and is affected by volatile anesthetics. ( Badgwell, JM; Heavner, JE; Kytta, J, 1990) |
| " They then compared these dose-response relationships with values obtained for adults (greater than 18 years old) under comparable anesthetic conditions." | 1.27 | Neuromuscular effects of vecuronium (ORG NC45) in infants and children during N2O, halothane anesthesia. ( Fisher, DM; Miller, RD, 1983) |
| " The elimination half-life (t beta 1/2) was 174 +/- 60 min in neonates, significantly longer than the values of 90 +/- 23 and 89 +/- 18 min in children and adults, respectively." | 1.26 | Pharmacokinetics and pharmacodynamics of d-tubocurarine in infants, children, and adults. ( Cronnelly, R; Fisher, DM; Gregory, GA; Miller, RD; O'Keeffe, C; Stanski, DR, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (37.70) | 18.7374 |
| 1990's | 24 (39.34) | 18.2507 |
| 2000's | 12 (19.67) | 29.6817 |
| 2010's | 2 (3.28) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zier, JL | 1 |
| Tarrago, R | 1 |
| Liu, M | 1 |
| Mawhinney, LJ | 1 |
| de Rivero Vaccari, JP | 1 |
| Alonso, OF | 1 |
| Jimenez, CA | 1 |
| Furones, C | 1 |
| Moreno, WJ | 1 |
| Lewis, MC | 2 |
| Dietrich, WD | 1 |
| Bramlett, HM | 1 |
| Beals, JK | 1 |
| Carter, LB | 2 |
| Jevtovic-Todorovic, V | 2 |
| BERGSTROEM-WALAN, MB | 1 |
| WESTON, TE | 1 |
| ALLEN, GD | 1 |
| TOLAS, A | 1 |
| SMITH, JD | 1 |
| Culley, DJ | 4 |
| Baxter, MG | 3 |
| Yukhananov, R | 4 |
| Crosby, G | 4 |
| Mitsui, T | 2 |
| Kondo, T | 1 |
| Crosby, CA | 1 |
| Loguinov, A | 1 |
| Gerenstein, RI | 1 |
| Chidiac, G | 1 |
| Raghavan, SV | 1 |
| Waly, M | 1 |
| Deth, RC | 1 |
| Matsuura, T | 1 |
| Oda, Y | 1 |
| Ikeshita, K | 1 |
| Nishikawa, K | 1 |
| Ito, K | 1 |
| Asada, A | 1 |
| Fisher, DM | 5 |
| Miller, RD | 4 |
| Crumrine, RS | 1 |
| Yodlowski, EH | 1 |
| Linnell, JC | 1 |
| Matthews, DM | 1 |
| Sear, JW | 1 |
| Prys-Roberts, C | 1 |
| Phillips, KC | 1 |
| Koblin, DD | 5 |
| Lurz, FW | 2 |
| Eger, EI | 6 |
| O'Keeffe, C | 1 |
| Stanski, DR | 1 |
| Cronnelly, R | 1 |
| Gregory, GA | 1 |
| Kristoffersen, MB | 1 |
| Kjaer Hansen, EK | 1 |
| Jostell, KG | 1 |
| Stockman, O | 1 |
| Johanson, CE | 1 |
| Preston, JE | 1 |
| Gold, MI | 1 |
| Abello, D | 1 |
| Herrington, C | 1 |
| Matteo, RS | 2 |
| Ornstein, E | 2 |
| Schwartz, AE | 2 |
| Ostapkovich, N | 1 |
| Stone, JG | 1 |
| Ohno, F | 1 |
| Imakiire, T | 1 |
| Nobori, T | 1 |
| Ohyama, M | 1 |
| Taguchi, N | 1 |
| Nishikawa, T | 1 |
| Inomata, S | 1 |
| Taguchi, M | 1 |
| Yamashita, S | 1 |
| Naito, H | 1 |
| Fragen, RJ | 1 |
| Dunn, KL | 1 |
| Ozaki, M | 1 |
| Sessler, DI | 1 |
| Matsukawa, T | 1 |
| Ozaki, K | 1 |
| Atarashi, K | 1 |
| Negishi, C | 1 |
| Suzuki, H | 1 |
| Goudsouzian, N | 1 |
| Chakravorti, S | 1 |
| Denman, W | 1 |
| Schwartz, A | 1 |
| Yang, HS | 1 |
| Cook, DR | 1 |
| Kato, N | 1 |
| Shimaoka, K | 1 |
| Miyamura, M | 1 |
| Markakis, DA | 1 |
| Lau, M | 1 |
| Brown, R | 1 |
| Luks, AM | 1 |
| Sharma, ML | 1 |
| Kudoh, A | 1 |
| Sakai, T | 1 |
| Ishihara, H | 1 |
| Matsuki, A | 1 |
| Fujinaga, M | 1 |
| Doone, R | 1 |
| Davies, MF | 1 |
| Maze, M | 1 |
| Deleu, D | 1 |
| Louon, A | 1 |
| Sivagnanam, S | 1 |
| Sundaram, K | 1 |
| Okereke, P | 1 |
| Gravell, D | 1 |
| Al-Salmy, HS | 1 |
| Al Bahrani, I | 1 |
| Nam, D | 1 |
| Knox-MacAulay, H | 1 |
| Hanssens, Y | 1 |
| Schneede, J | 1 |
| Refsum, H | 1 |
| Ueland, PM | 1 |
| Crane, L | 1 |
| Gootman, N | 1 |
| Gootman, PM | 2 |
| Everman, BW | 1 |
| Lien, CA | 1 |
| Diaz, J | 1 |
| Murray, DJ | 1 |
| Mehta, MP | 1 |
| Forbes, RB | 1 |
| Palmisano, BW | 1 |
| Setlock, MA | 1 |
| Brown, MP | 1 |
| Siker, D | 1 |
| Tripuraneni, R | 1 |
| Rampil, IJ | 2 |
| Lockhart, SH | 1 |
| Zwass, MS | 1 |
| Peterson, N | 1 |
| Yasuda, N | 1 |
| Weiskopf, RB | 1 |
| Damask, MC | 1 |
| Lampe, GH | 4 |
| Wauk, LZ | 4 |
| Whitendale, P | 3 |
| Way, WL | 2 |
| Kozmary, SV | 1 |
| Donegan, JH | 2 |
| Rupp, SM | 1 |
| Fouts, KE | 1 |
| Rose, BM | 1 |
| Litt, LL | 1 |
| Wilson, CB | 1 |
| Murray, W | 1 |
| Tomerson, BW | 2 |
| Waldman, FM | 2 |
| Kitts, JB | 1 |
| Canfell, PC | 1 |
| Spellman, MJ | 1 |
| Caldwell, JE | 1 |
| Heier, T | 1 |
| Fahey, MR | 1 |
| Kitahara, Y | 1 |
| Kojima, Y | 1 |
| Nozaki, F | 1 |
| Badgwell, JM | 1 |
| Heavner, JE | 1 |
| Kytta, J | 1 |
| Debaene, B | 1 |
| Meistelman, C | 1 |
| d'Hollander, A | 1 |
| Lind, RC | 1 |
| Gandolfi, AJ | 1 |
| Hall, PD | 1 |
| Castagnoli, K | 1 |
| Baughman, VL | 1 |
| Hoffman, WE | 1 |
| Miletich, DJ | 1 |
| Albrecht, RF | 1 |
| Lemmens, HJ | 1 |
| Bovill, JG | 1 |
| Hennis, PJ | 1 |
| Burm, AG | 1 |
| Roizen, MF | 1 |
| Johnson, BH | 1 |
| Bainton, CR | 1 |
| Mullenix, PJ | 1 |
| Moore, PA | 1 |
| Tassinari, MS | 1 |
| Mosher, GL | 1 |
| Robinson, RH | 1 |
| Ikeda, K | 1 |
| Iwabuchi, T | 1 |
| Kutsuzawa, T | 1 |
| Nakamura, T | 1 |
| Crane, LA | 1 |
| Gootman, NL | 1 |
| Kitamura, H | 1 |
| Sawa, T | 1 |
| Ikezono, E | 1 |
| Becklake, MR | 1 |
| Frank, H | 1 |
| Dagenais, GR | 1 |
| Ostiguy, GL | 1 |
| Guzman, CA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Dexmedetomidine on the Incidence of Postoperative Delirium in Patients After Cardiac Surgery: a Randomized, Double-blinded, and Placebo-controlled Clinical Trial[NCT02267538] | Phase 4 | 285 participants (Actual) | Interventional | 2014-11-30 | Completed | ||
| Association Between Changes in Cerebral Gray Matter Volume and Postoperative Cognitive Dysfunction in Elderly Patients Following Sevoflurane Anesthesia (POCD-MRI)[NCT02045004] | 100 participants (Actual) | Observational | 2015-07-14 | Completed | |||
| A Prospective Randomized Clinical Trial Evaluating the Effect of Convective Pre-warming on Intra-operative Thermoregulatory Capabilities in Patients Enrolled in the TIGER Anesthesia Perioperative Protocol[NCT03876808] | 10 participants (Actual) | Interventional | 2017-10-26 | Terminated (stopped due to Poor participant recruitment) | |||
| The Quality of Recovery After General Anesthesia With Desflurane and Sevoflurane in Endoscopic Ureteral Lithotripsy[NCT04712162] | 60 participants (Actual) | Interventional | 2019-11-19 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Delirium was assessed with the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) twice daily during the first five days after surgery. (NCT02267538)
Timeframe: During the first five days after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| DEX Group | 7 |
| CTRL Group | 11 |
Results was presented as median (95% confidence interval). (NCT02267538)
Timeframe: From end of surgery until discharge from hospital or 30 days after surgery
| Intervention | days (Median) |
|---|---|
| DEX Group | 9 |
| CTRL Group | 9 |
Results was presented as median (95% confidence interval). (NCT02267538)
Timeframe: From end of surgery until discharge from Intensive Care Unit or 30 days after surgery
| Intervention | hours (Median) |
|---|---|
| DEX Group | 45.0 |
| CTRL Group | 46.0 |
"Cognitive function was assessed with the Mini Mental State Examination (MMSE) at baseline (the day before surgery) and on the sixth day after surgery, and with modified telephone interview for cognitive status (m-TICS) on the 30th day after surgery.~The introduction of MMSE scale has been explained in the baseline part in the result section.~The Telephone Interview for Cognitive Status-modified scale(m-TICS) is one of the most popular telephone interview-based screening instruments for mild cognitive impairment and dementia. It consists 11 items including wordlist memory, orientation, attention, repetition, conceptual knowledge and nonverbal praxis, which score ranges from 0 to 48, with higher scores indicating better cognitive function" (NCT02267538)
Timeframe: on the sixth day after surgery, and on the 30th day after surgery
| Intervention | units on a scale (Median) | |
|---|---|---|
| MMSE score on postoperative day 6 | m-TICS score on postoperative day 30 | |
| CTRL Group | 29 | 34 |
| DEX Group | 29 | 34 |
Non-delirium complications was defined as any conditions other than delirium that occurred during the first 30 days after surgery and required therapeutic intervention.Complications listed here were not considered adverse events in this study. (NCT02267538)
Timeframe: Occurrence of non-delirium complications will be monitored until 30 days after surgery.
| Intervention | Participants (Count of Participants) | |||||||
|---|---|---|---|---|---|---|---|---|
| Stroke | New onset arrythmia | Pulmonary complications | Upper gastrointestinal bleeding | Surgical bleeding | Wound dehiscence or infection | Acute kidney injury | IABP assistance | |
| CTRL Group | 3 | 51 | 27 | 4 | 3 | 7 | 44 | 12 |
| DEX Group | 3 | 42 | 15 | 2 | 3 | 11 | 37 | 6 |
Pain intensity was assessed daily at 8 am during the first five days after surgery with the Numeric Rating Scale (NRS, 0 = no pain, 10 = the worst possible pain). (NCT02267538)
Timeframe: During the first five days after surgery
| Intervention | units on a scale (Median) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Pain score after surgery(d1), at rest | Pain score after surgery(d2), at rest | Pain score after surgery(d3), at rest | Pain score after surgery(d4), at rest | Pain score after surgery(d5), at rest | Pain score after surgery(d1), with coughing | Pain score after surgery(d2), with coughing | Pain score after surgery(d3), with coughing | Pain score after surgery(d4), with coughing | Pain score after surgery(d5), with coughing | |
| CTRL Group | 3 | 3 | 2 | 2 | 1 | 4 | 4 | 4 | 3 | 2 |
| DEX Group | 3 | 4 | 3 | 2 | 2 | 4 | 5 | 4 | 3 | 2 |
Subjective sleep quality was assessed daily at 8 am during the first five days after surgery with the Numeric Rating Scale (NRS, 0 = best sleep, 10 = the worst possible sleep). (NCT02267538)
Timeframe: During the first five days after surgery
| Intervention | units on a scale (Median) | ||||
|---|---|---|---|---|---|
| Subjective sleep quality after surgery(d1), score | Subjective sleep quality after surgery(d2), score | Subjective sleep quality after surgery(d3), score | Subjective sleep quality after surgery(d4), score | Subjective sleep quality after surgery(d5), score | |
| CTRL Group | 2 | 3 | 2 | 2 | 2 |
| DEX Group | 2 | 3 | 2 | 2 | 2 |
Change in core temperature between induction of anesthesia and end of skin preparation (NCT03876808)
Timeframe: Day 1
| Intervention | Degrees Celsius (Mean) |
|---|---|
| Convective Pre-warming | -0.95 |
| Standard of Care | -0.53 |
Core body temperature measured intraoperatively (NCT03876808)
Timeframe: Day 1
| Intervention | Degrees Celsius (Mean) |
|---|---|
| Convective Pre-warming | 36.0 |
| Standard of Care | 35.7 |
Change in skin temperature between arrival to the holding area and departure to the operating room, and arrival to the PACU (NCT03876808)
Timeframe: Day 1
| Intervention | Degrees Celsius (Mean) | |
|---|---|---|
| Holding area to operating room departure | Holding area to arrival in PACU | |
| Convective Pre-warming | -0.03 | -0.07 |
| Standard of Care | 0.08 | -0.48 |
Differences in temperature changes between elderly (≥ 65 years) and younger patients (< 65 years). (NCT03876808)
Timeframe: Day 1
| Intervention | Degrees Celcius (Mean) |
|---|---|
| Temperature before prewarming - Patients >65 years of age | |
| Standard of Care | 36.5 |
Differences in temperature changes between elderly (≥ 65 years) and younger patients (< 65 years). (NCT03876808)
Timeframe: Day 1
| Intervention | Degrees Celcius (Mean) | |||
|---|---|---|---|---|
| Temperature before prewarming - Patients <65 years of age | Temperature before prewarming - Patients >65 years of age | Temperature after prewarming - Patients <65 years of age | Temperature after prewarming - Patients >65 years of age | |
| Convective Pre-warming | 36.5 | 36.6 | 36.5 | 36.4 |
2 reviews available for nitrous oxide and Aging
| Article | Year |
|---|---|
Cobalamin metabolism and its clinical aspects.
Topics: Adolescent; Adult; Aged; Aging; Animals; Child; Child, Preschool; Cobamides; Cyanides; Female; Food | 1984 |
Biological and environmental determinants of plasma homocysteine.
Topics: Adult; Aged; Aging; Alcohol Drinking; Child; Cystathionine beta-Synthase; Diagnosis-Related Groups; | 2000 |
11 trials available for nitrous oxide and Aging
| Article | Year |
|---|---|
Differential electroencephalographic response to tracheal intubation between young and elderly during isoflurane and sevoflurane nitrous oxide anaesthesia.
Topics: Adult; Aged; Aged, 80 and over; Aging; Anesthetics, Combined; Anesthetics, Inhalation; Blood Pressur | 2007 |
Age influences the minimum infusion rate (ED50) for continuous infusions of Althesin and methohexitone.
Topics: Adult; Aged; Aging; Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Dose-Response Relationsh | 1984 |
Hemodynamic effects of intravenous ephedrine in infants and children anesthetized with halothane and nitrous oxide.
Topics: Adolescent; Adrenergic Agonists; Aging; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Press | 1996 |
The minimum alveolar concentration (MAC) of sevoflurane with and without nitrous oxide in elderly versus young adults.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anesthetics, Inhalation; Cross-Over Studies; Dose | 1996 |
Prolonged mivacurium infusion in young and elderly adults.
Topics: Adolescent; Adult; Aged; Aging; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inh | 1997 |
The pharmacokinetics and steady state pharmacodynamics of mivacurium in children.
Topics: Adolescent; Adult; Aging; Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Child, Preschool; | 1998 |
Long-term effects of nitrous oxide anaesthesia on laboratory and clinical parameters in elderly Omani patients: a randomized double-blind study.
Topics: Aged; Aging; Anesthetics, Inhalation; Double-Blind Method; Female; Folic Acid; Hemoglobins; Humans; | 2000 |
The additive contribution of nitrous oxide to isoflurane MAC in infants and children.
Topics: Aging; Anesthesia, Inhalation; Drug Synergism; Humans; Infant; Isoflurane; Nitrous Oxide; Pediatrics | 1991 |
Postoperative hypoxemia after nonabdominal surgery: a frequent event not caused by nitrous oxide.
Topics: Adult; Aged; Aging; Anesthesia, Inhalation; Female; Humans; Hypoxia; Intraoperative Period; Isoflura | 1990 |
Nitrous oxide and epinephrine-induced arrhythmias.
Topics: Adult; Aging; Anesthesia, Inhalation; Arrhythmias, Cardiac; Electrocardiography; Epinephrine; Female | 1990 |
Nitrous oxide does not impair hepatic function in young or old surgical patients.
Topics: Aged; Aging; Anesthesia, Inhalation; Female; Humans; Liver; Liver Function Tests; Male; Middle Aged; | 1990 |
48 other studies available for nitrous oxide and Aging
| Article | Year |
|---|---|
Level of sedation with nitrous oxide for pediatric medical procedures.
Topics: Adolescent; Aging; Anesthetics, Inhalation; Child; Child, Preschool; Conscious Sedation; Dental Anxi | 2010 |
Isoflurane/nitrous oxide anesthesia induces increases in NMDA receptor subunit NR2B protein expression in the aged rat brain.
Topics: Aging; Analysis of Variance; Anesthetics, Inhalation; Animals; Brain; Caspase 3; Cell Death; Dose-Re | 2012 |
Neurotoxicity of nitrous oxide and ketamine is more severe in aged than in young rat brain.
Topics: Aging; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Cerebral Cortex; Female; Ketamin | 2003 |
EFFICACY OF EDUCATION FOR CHILDBIRTH.
Topics: Aging; Anxiety; Blood Pressure; Education; Female; Humans; Hypnotics and Sedatives; Labor, Obstetric | 1963 |
PRESBYACUSIS. A CLINICAL STUDY.
Topics: Aging; Anesthesia; Bendroflumethiazide; Cardiovascular Diseases; Ethinyl Estradiol; Geriatrics; Hear | 1964 |
BLOOD PRESSURE CHANGES DURING DENTAL ANESTHESIA.
Topics: Adolescent; Aging; Anesthesia; Anesthesia, Dental; Blood Pressure; Blood Pressure Determination; Chi | 1965 |
Long-term impairment of acquisition of a spatial memory task following isoflurane-nitrous oxide anesthesia in rats.
Topics: Aging; Analysis of Variance; Anesthesia, General; Anesthetics, Inhalation; Animals; Isoflurane; Male | 2004 |
Increased breath nitrous oxide after ingesting nitrate in patients with atrophic gastritis and partial gastrectomy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Breath Tests; Female; Gastrectomy; Gastritis, Atr | 2004 |
Impaired acquisition of spatial memory 2 weeks after isoflurane and isoflurane-nitrous oxide anesthesia in aged rats.
Topics: Aging; Anesthetics, Combined; Anesthetics, Inhalation; Animals; Cognition; Isoflurane; Maze Learning | 2004 |
The anesthetics nitrous oxide and ketamine are more neurotoxic to old than to young rat brain.
Topics: Aging; Anesthetics; Animals; Brain; Dose-Response Relationship, Drug; Drug Combinations; Female; Ket | 2005 |
General anesthesia does not reduce life expectancy in aged rats.
Topics: Aging; Anesthesia, General; Animals; Isoflurane; Life Expectancy; Longevity; Male; Nitrous Oxide; Ra | 2006 |
Onset time for sevoflurane/nitrous oxide induction in adults is prolonged with increasing age.
Topics: Adult; Aged; Aging; Anesthesia, Inhalation; Anesthetics, Inhalation; Electroencephalography; Eyelash | 2006 |
Nitrous oxide decreases cortical methionine synthase transiently but produces lasting memory impairment in aged rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aging; Animals; Cerebral Cortex; Male; Me | 2007 |
Neuromuscular effects of vecuronium (ORG NC45) in infants and children during N2O, halothane anesthesia.
Topics: Adolescent; Adult; Aging; Anesthesia, Inhalation; Child; Child, Preschool; Electromyography; Halotha | 1983 |
Assessment of neuromuscular function in infants.
Topics: Action Potentials; Aging; Child, Preschool; Electric Stimulation; Electromyography; Humans; Infant; | 1981 |
Age-dependent alterations in nitrous oxide requirement of mice.
Topics: Aging; Anesthesia, Inhalation; Animals; Dose-Response Relationship, Drug; Drug Resistance; Male; Mic | 1983 |
Pharmacokinetics and pharmacodynamics of d-tubocurarine in infants, children, and adults.
Topics: Adolescent; Adult; Aging; Anesthesia, General; Child; Child, Preschool; Electromyography; Half-Life; | 1982 |
Chlormethiazole (Heminevrin), pethidine and nitrous oxide as compared to halothane for general anesthesia.
Topics: Aged; Aging; Anesthesia, General; Chlormethiazole; Halothane; Humans; Kinetics; Meperidine; Middle A | 1982 |
Potassium efflux from infant and adult rat choroid plexuses: effects of CSF anion substitution, N-ethylmaleimide and Cl transport inhibitors.
Topics: Aging; Animals; Anions; Benzoates; Bumetanide; Chlorides; Choroid Plexus; Ethylmaleimide; Female; Fu | 1994 |
Minimum alveolar concentration of desflurane in patients older than 65 yr.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anesthetics; Desflura | 1993 |
Pharmacokinetics and pharmacodynamics of rocuronium (Org 9426) in elderly surgical patients.
Topics: Adult; Aged; Aging; Androstanols; Anesthesia, Inhalation; Anesthesia, Intravenous; Female; Fentanyl; | 1993 |
[Gas ventilation through middle ear mucosa].
Topics: Acoustic Impedance Tests; Adolescent; Adult; Aged; Aging; Anesthesia, General; Child; Child, Prescho | 1993 |
The threshold for thermoregulatory vasoconstriction during nitrous oxide/sevoflurane anesthesia is reduced in the elderly.
Topics: Adult; Aged; Aged, 80 and over; Aging; Anesthetics, Combined; Anesthetics, Inhalation; Body Temperat | 1997 |
Effect of aging on the concentrations of nitrous oxide in exhaled air.
Topics: Adolescent; Adult; Aged; Aging; Bacteria; Breath Tests; Child; Child, Preschool; Female; Humans; Mal | 1997 |
Renin-aldosterone in elderly patients with hyperkalaemia under anaesthesia.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Anesthesia, General; Anesthetics, Inhalation; An | 1999 |
Nitrous oxide lacks the antinociceptive effect on the tail flick test in newborn rats.
Topics: Aging; Analgesics, Non-Narcotic; Animals; Animals, Newborn; Female; Male; Nitrous Oxide; Pain; Pain | 2000 |
Age-dependent cardiovascular effects of halothane anesthesia in neonatal pigs.
Topics: Aging; Anesthesia; Animals; Animals, Newborn; Blood Pressure; Halothane; Heart Rate; Hemodynamics; N | 1975 |
Aging, chronic administration of ethanol, and acute exposure to nitrous oxide: effects on vitamin B12 and folate status in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aging; Alcoholism; Animals; Disease Model | 1992 |
Distribution, elimination, and action of vecuronium in the elderly.
Topics: Adult; Aged; Aged, 80 and over; Aging; Anesthesia; Fentanyl; Humans; Middle Aged; Nitrous Oxide; Sur | 1991 |
Dose-response for atropine and heart rate in infants and children anesthetized with halothane and nitrous oxide.
Topics: Aging; Anesthesia, Inhalation; Atropine; Blood Pressure; Child; Child, Preschool; Dose-Response Rela | 1991 |
Clinical characteristics of desflurane in surgical patients: minimum alveolar concentration.
Topics: Adult; Aging; Anesthesia Recovery Period; Anesthesia, Inhalation; Desflurane; Humans; Isoflurane; Mi | 1991 |
Effect of nitrous oxide on folate and vitamin B12 metabolism in patients.
Topics: Adult; Aged; Aging; Female; Folic Acid; Formiminoglutamic Acid; Humans; Male; Middle Aged; Nitrous O | 1990 |
Pharmacokinetics and pharmacodynamics of atracurium in the elderly.
Topics: Adult; Aged; Aging; Anesthesia, Inhalation; Atracurium; Halothane; Humans; Neuromuscular Junction; N | 1990 |
[Aperiodic analysis of EEG in children during halothane anesthesia].
Topics: Aging; Anesthesia, Inhalation; Child; Child, Preschool; Electroencephalography; Female; Halothane; H | 1990 |
Bupivacaine toxicity in young pigs is age-dependent and is affected by volatile anesthetics.
Topics: Aging; Animals; Arrhythmias, Cardiac; Blood Pressure; Bupivacaine; Cardiac Output; Drug Interactions | 1990 |
Disruption of folate and vitamin B12 metabolism in aged rats following exposure to nitrous oxide.
Topics: Aging; Animals; Brain; Folic Acid; Kidney; Liver; Male; Nitrous Oxide; Rats; Rats, Inbred F344; Vita | 1990 |
Recovery from vecuronium neuromuscular blockade following neostigmine administration in infants, children, and adults during halothane anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, Inhalation; Child; Child, Preschool; Halothane; Humans; Infant; Midd | 1989 |
Age and gender influence halothane-associated hepatotoxicity in strain 13 guinea pigs.
Topics: Aging; Anesthesia, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Female; Guinea Pigs; | 1989 |
Vecuronium kinetics and dynamics in anesthetized infants and children.
Topics: Aging; Anesthesia; Child, Preschool; Female; Halothane; Humans; Infant; Infusions, Parenteral; Kinet | 1985 |
Effects of phenobarbital on cerebral blood flow and metabolism in young and aged rats.
Topics: Aging; Anesthesia, Inhalation; Animals; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circu | 1986 |
Age has no effect on the pharmacodynamics of alfentanil.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alfentanil; Anesthesia; Dose-Response Relationship, Drug; Fem | 1988 |
Mechanism of age-related and nitrous oxide-associated anesthetic sensitivity: the role of brain catecholamines.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain Chemistry; Dopamine; Drug Resistance; Male; Mi | 1988 |
Behavioral toxicity of nitrous oxide in rats following prenatal exposure.
Topics: Aging; Animals; Behavior, Animal; Female; Motor Activity; Nitrous Oxide; Pregnancy; Prenatal Exposur | 1986 |
Anesthesia for fractured hips. Innovar versus halothane.
Topics: Adult; Aged; Aging; Benperidol; Drug Combinations; Female; Fentanyl; Fractures, Bone; Halothane; Hip | 1972 |
Relationship between cerebral blood flow and arterial blood pressure in patients with apoplexy.
Topics: Adult; Aged; Aging; Blood Pressure; Cerebrovascular Circulation; Cerebrovascular Disorders; Humans; | 1973 |
The effects of decamethonium (C-10) on blood pressure and heart rate in newborn piglets.
Topics: Acetylcholine; Aging; Anesthesia; Animals; Animals, Newborn; Blood Pressure; Carbon Dioxide; Decamet | 1974 |
Postoperative hypoxemia: The contribution of age to the maldistribution of ventilation.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Aging; Anesthesia, General; Child; Female; Halothane | 1972 |
Influence of age and sex on exercise cardiac output.
Topics: Adult; Aged; Aging; Blood Circulation; Cardiac Output; Female; Heart; Heart Rate; Humans; Male; Midd | 1965 |