nitrous oxide and Age-Related Memory Disorders

nitrous oxide has been researched along with Age-Related Memory Disorders in 8 studies

Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.

Research

Studies (8)

Authors

Clinical Trials (7)

Trial Overview

Trial Outcomes

Mean Anxiety Score Experienced During Version

Anxiety scores will be collected following each version attempt using an 11 point scale (0 being not at all anxious; 10 being extremely anxious), ranging from 0 to 10. Higher scores indicate more anxiety, lower scores indicate less anxiety. If more than one attempt, anxiety scores will be averaged to obtain a single score for the entire procedure. (NCT03502915)
Timeframe: During each version procedure, a total average of up to approximately 30 minutes

Mean Pain Score Experienced During Version

Pain scores will be collected following each version attempt using an 11 point scale (with 0 being no pain at all; 10 being worst pain imaginable), ranging from 0 to 10. Higher scores indicate more pain, lower scores indicate less pain. If more than one attempt, pain scores will be averaged to obtain a single score for the entire procedure. (NCT03502915)
Timeframe: During each version procedure, a total average of up to approximately 30 minutes

Mean Post-procedure Pain Score

Pain scores will be collected following completion of the version using an 11 point scale (0 being no pain at all; 10 being worst pain imaginable), ranging from 0 to 10. Higher scores indicate more pain, lower scores indicate less pain. (NCT03502915)
Timeframe: Immediately Post-procedure, within approximately 15 minutes of final version attempt

Mean Post-procedure Patient Satisfaction Score

Satisfaction will be assessed following the procedure using an 11 point scale (0 being not at all satisfied; 10 being extremely satisfied), ranging from 0 to 10. Higher scores indicate more satisfaction, lower scores indicate less satisfaction. (NCT03502915)
Timeframe: Immediately Post-procedure, within approximately 15 minutes of final version attempt

Mean Post-procedure Provider Assessed Level of Difficulty Score

Following the procedure, the obstetric provider performing the procedure will rate the ease of procedure on a 1-10 scale (1 being very easy and 10 being extremely difficult), ranging from 1 to 10. Higher scores indicate more difficulty, lower scores indicate less difficulty. A 10 point scale was used for this outcome, while an 11 point scale was used for the other 4 outcome measures (pain, anxiety, post-procedure pain and satisfaction). (NCT03502915)
Timeframe: Immediately Post-procedure, within approximately 15 minutes of final version attempt

Incidence of Postoperative Delirium

Delirium was assessed with the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) twice daily during the first five days after surgery. (NCT02267538)
Timeframe: During the first five days after surgery

Length of Stay in Hospital After Surgery

Results was presented as median (95% confidence interval). (NCT02267538)
Timeframe: From end of surgery until discharge from hospital or 30 days after surgery

Length of Stay in the Intensive Care Unit

Results was presented as median (95% confidence interval). (NCT02267538)
Timeframe: From end of surgery until discharge from Intensive Care Unit or 30 days after surgery

Cognitive Function

"Cognitive function was assessed with the Mini Mental State Examination (MMSE) at baseline (the day before surgery) and on the sixth day after surgery, and with modified telephone interview for cognitive status (m-TICS) on the 30th day after surgery.~The introduction of MMSE scale has been explained in the baseline part in the result section.~The Telephone Interview for Cognitive Status-modified scale(m-TICS) is one of the most popular telephone interview-based screening instruments for mild cognitive impairment and dementia. It consists 11 items including wordlist memory, orientation, attention, repetition, conceptual knowledge and nonverbal praxis, which score ranges from 0 to 48, with higher scores indicating better cognitive function" (NCT02267538)
Timeframe: on the sixth day after surgery, and on the 30th day after surgery

Incidence of Non-delirium Complications After Surgery

Non-delirium complications was defined as any conditions other than delirium that occurred during the first 30 days after surgery and required therapeutic intervention.Complications listed here were not considered adverse events in this study. (NCT02267538)
Timeframe: Occurrence of non-delirium complications will be monitored until 30 days after surgery.

Pain Intensity

Pain intensity was assessed daily at 8 am during the first five days after surgery with the Numeric Rating Scale (NRS, 0 = no pain, 10 = the worst possible pain). (NCT02267538)
Timeframe: During the first five days after surgery

Subjective Sleep Quality

Subjective sleep quality was assessed daily at 8 am during the first five days after surgery with the Numeric Rating Scale (NRS, 0 = best sleep, 10 = the worst possible sleep). (NCT02267538)
Timeframe: During the first five days after surgery

Trials

1 trial available for nitrous oxide and Age-Related Memory Disorders

Other Studies

7 other studies available for nitrous oxide and Age-Related Memory Disorders