Compounds > nitrous oxide
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nitrous oxide and Abnormalities, Drug-Induced

nitrous oxide has been researched along with Abnormalities, Drug-Induced in 46 studies

Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research Excerpts

ExcerptRelevanceReference
" N2O itself did not cause situs inversus but increased the incidence of phenylephrine-induced situs inversus."3.69Methionine prevents nitrous oxide-induced teratogenicity in rat embryos grown in culture. ( Baden, JM; Fujinaga, M, 1994)
" One such possibility is that N2O causes adverse reproductive toxicity secondary to its sympathomimetic effects."1.28Preventive effects of phenoxybenzamine on nitrous oxide-induced reproductive toxicity in Sprague-Dawley rats. ( Baden, JM; Fujinaga, M; Mazze, RI; Myatt, JK; Suto, A, 1991)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199036 (78.26)18.7374
1990's7 (15.22)18.2507
2000's3 (6.52)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Starek, A1
Struciński, P1
Dobrzańska-Tatarczuch, L1
Olfert, SM1
Fink, BR1
Shepard, TH2
Blandau, RJ1
Baden, JM12
Simmon, VF1
Stoklov, M1
Trouiller, P1
Stieglitz, P1
Lamalle, Y1
Vincent, F1
Perdrix, A1
Marka, C1
de Gaudemaris, R1
Mallion, JM1
Faure, J1
Mazze, RI10
Wilson, AI2
Rice, SA3
Vieira, E3
Cleaton-Jones, P2
Moyes, D1
Green, CJ1
Austin, JC1
Moyes, DG1
Shaw, R1
Nunn, JF3
Dale, O1
Husum, B1
Fujinaga, M10
Meskin, LH1
Miller, MC1
Maze, M1
Goldstein, BD1
Paz, J1
Giuffrida, JG1
Palmes, ED1
Ferrand, EF1
Shah, RM1
Burdett, DN1
Donaldson, D1
Garro, AJ1
Phillips, RA1
Milliken, RA1
Rendell-Baker, L1
Bussard, DA1
Phairas, D1
Agarkov, VI1
Dotsenko, TM1
Shterliaev, VN1
Buteva, LV1
Severin, GK1
Pivneva, TI1
Koktyshev, IV1
Suto, A1
Myatt, JK1
Hansen, DK1
Billings, RE1
Fantel, AG1
Keeling, PA1
Rocke, DA1
Monk, SJ1
Lumb, MJ1
Halsey, MJ1
Eger, EI1
Gaskey, NJ1
Yhap, EO1
Sato, T1
Crawford, JS1
Lewis, M1
Aldridge, LM1
Tunstall, ME1
Harris, SB1
Spierdijk, J1
Regjer, V1
Smith, BE1
Pilon, RN1
Corbett, TH1
Parbrook, GD1
Parkhouse, J1

Reviews

6 reviews available for nitrous oxide and Abnormalities, Drug-Induced

ArticleYear
[Health hazard for medical staff exposed to nitrous oxide].
    Roczniki Panstwowego Zakladu Higieny, 2004, Volume: 55, Issue:3

    Topics: Abnormalities, Drug-Induced; Air Pollutants, Occupational; Anesthetics, Inhalation; Bone Marrow; Cen

2004
Reproductive outcomes among dental personnel: a review of selected exposures.
    Journal (Canadian Dental Association), 2006, Volume: 72, Issue:9

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anesthetics, Inhalation; Dental Disinfectants; D

2006
Mutagenic effects of inhalational anesthetics.
    Mutation research, 1980, Volume: 75, Issue:2

    Topics: Abnormalities, Drug-Induced; Anesthesia, Inhalation; Anesthetics; Animals; Cell Division; Cricetinae

1980
Anaesthetic gases and health risks to laboratory personnel: a review.
    Laboratory animals, 1981, Volume: 15, Issue:4

    Topics: Abnormalities, Drug-Induced; Anesthesia, Inhalation; Anesthetics; Animals; Chemical and Drug Induced

1981
Congenital anomalies and inhalation anesthetics.
    Journal of the American Dental Association (1939), 1976, Volume: 93, Issue:3

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anesthesia, Inhalation; Anesthetics; Animals; Co

1976
Anaesthesia and cell division.
    Annals of the Royal College of Surgeons of England, 1971, Volume: 48, Issue:2

    Topics: Abnormalities, Drug-Induced; Anesthetics; Animals; Chick Embryo; Chromosomes; Colchicine; Cyclopropa

1971

Other Studies

40 other studies available for nitrous oxide and Abnormalities, Drug-Induced

ArticleYear
Teratogenic activity of nitrous oxide.
    Nature, 1967, Apr-08, Volume: 214, Issue:5084

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Female; Fetal Death; Male; Nitrous Oxide; Pregnan

1967
[Exposure to anesthetic gases: risk and prevention].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1983, Sep-01, Volume: 59, Issue:29-30

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Air Pollutants, Occupational; Anesthesia, Inhala

1983
Reproduction and fetal development in rats exposed to nitrous oxide.
    Teratology, 1984, Volume: 30, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Behavior, Animal; Deoxyuridine; Dose-Response Relationship, Dr

1984
Effects of low intermittent concentrations of nitrous oxide on the developing rat fetus.
    British journal of anaesthesia, 1983, Volume: 55, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Bone and Bones; Female; Fetal Death; Fetal Resorp

1983
Reproduction and fetal development in mice chronically exposed to nitrous oxide.
    Teratology, 1982, Volume: 26, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Female; Fetus; Male; Mice; M

1982
Effects of low concentrations of nitrous oxide on rat fetuses.
    Anesthesia and analgesia, 1980, Volume: 59, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Resorption; Fetus; Litter Size; Maximum Allowabl

1980
Faulty cell replication: abortion, congenital abnormalities.
    International anesthesiology clinics, 1981,Winter, Volume: 19, Issue:4

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anesthetics; Animals; Cell Division; Cells, Cult

1981
Nitrous oxide: at threat to personnel and global environment?
    Acta anaesthesiologica Scandinavica, 1994, Volume: 38, Issue:8

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Air Pollutants; Female; Greenhouse Effect; Healt

1994
Methionine prevents nitrous oxide-induced teratogenicity in rat embryos grown in culture.
    Anesthesiology, 1994, Volume: 81, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Culture Techniques; Embryo, Mammalian; Female; Leucovorin; Mal

1994
No laughing matter.
    Journal of the American Dental Association (1939), 1993, Volume: 124, Issue:1

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Dental Staff; Female; Gas Scavengers; Humans; In

1993
The pregnant dental patient.
    Journal of the California Dental Association, 1995, Volume: 23, Issue:8

    Topics: Abnormalities, Drug-Induced; Contraindications; Dental Care; Dental Caries; Drug Utilization; Emerge

1995
Recent advances in understanding the actions and toxicity of nitrous oxide.
    Anaesthesia, 2000, Volume: 55, Issue:4

    Topics: Abnormalities, Drug-Induced; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Animals; Drug Tolera

2000
Editorial: Pregnancy and anaesthesia.
    Lancet (London, England), 1975, Jul-26, Volume: 2, Issue:7926

    Topics: Abnormalities, Drug-Induced; Anesthesia, Inhalation; Embryo, Mammalian; Environmental Exposure; Fema

1975
Atmospheric derivatives of anaesthetic gases as a possible hazard to operating-room personnel.
    Lancet (London, England), 1976, Jul-31, Volume: 2, Issue:7979

    Topics: Abnormalities, Drug-Induced; Anesthesia; Electricity; Environmental Exposure; Female; Humans; Hydroc

1976
Effect of the chronic administration of nitrous oxide 0.5% to gravid rats.
    British journal of anaesthesia, 1979, Volume: 51, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Female; Fetal Resorption; Fetus; Male; Nitrous

1979
The effects of nitrous oxide on the developing hamster embryos.
    Canadian journal of physiology and pharmacology, 1979, Volume: 57, Issue:11

    Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Embryo, Mammalian; Female; Fetal Resorption; Fetus

1979
Chronic anesthetic exposure--what is the margin of safety?
    Anesthesiology, 1979, Volume: 50, Issue:1

    Topics: Abnormalities, Drug-Induced; Anesthesiology; Animals; Dose-Response Relationship, Drug; Environmenta

1979
Wrongful birth and birth injury claims: new risks for oral surgeons.
    Journal of the Massachusetts Dental Society, 1992,Spring, Volume: 41, Issue:2

    Topics: Abnormalities, Drug-Induced; Anti-Bacterial Agents; Congenital Abnormalities; Contraceptives, Oral;

1992
[Mortality among infants with congenital anomalies in unfavorable hygienic conditions].
    Gigiena i sanitariia, 1991, Issue:12

    Topics: Abnormalities, Drug-Induced; Air Pollutants; Carbon Monoxide; Chemical Industry; Coke; Humans; Infan

1991
Preventive effects of phenoxybenzamine on nitrous oxide-induced reproductive toxicity in Sprague-Dawley rats.
    Teratology, 1991, Volume: 43, Issue:2

    Topics: Abnormalities, Drug-Induced; Analysis of Variance; Animals; Body Weight; Dose-Response Relationship,

1991
Effects of nitrous oxide on macromolecular content and DNA synthesis in rat embryos.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:3

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Abnormalities, Drug-Induced; Animals; DNA

1986
Effects of nitrous oxide on rat embryos grown in culture.
    Anesthesiology, 1989, Volume: 71, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; In Vitro Techniques; Nitrous Oxide; Rats

1989
Susceptible period of nitrous oxide teratogenicity in Sprague-Dawley rats.
    Teratology, 1989, Volume: 40, Issue:5

    Topics: Abnormalities, Drug-Induced; Analysis of Variance; Animals; Bone Development; Female; Fetal Death; G

1989
Halothane prevents nitrous oxide teratogenicity in Sprague-Dawley rats; folinic acid does not.
    Teratology, 1988, Volume: 38, Issue:2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Abnormalities, Drug-Induced; Animals; Fem

1988
Rat whole embryo culture: an in vitro model for testing nitrous oxide teratogenicity.
    Anesthesiology, 1988, Volume: 69, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Culture Techniques; DNA; Embryo, Mammalian; Embryonic Developm

1988
Folinic acid protection against nitrous oxide teratogenicity in the rat.
    British journal of anaesthesia, 1986, Volume: 58, Issue:5

    Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Embryonic and Fetal Development; Female; Fetal

1986
A review of the present status of nitrous oxide.
    AANA journal, 1986, Volume: 54, Issue:1

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Abnormalities, Drug-Induced; Agranulocyto

1986
Reproductive and teratogenic effects of nitrous oxide, fentanyl and their combination in Sprague-Dawley rats.
    British journal of anaesthesia, 1987, Volume: 59, Issue:10

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Drug Synergism; Female; Fentanyl; Nitrous Oxide;

1987
Reproductive and teratogenic effects of nitrous oxide, isoflurane, and their combination in Sprague-Dawley rats.
    Anesthesiology, 1987, Volume: 67, Issue:6

    Topics: Abnormalities, Drug-Induced; Anesthesia, Inhalation; Anesthesia, Obstetrical; Animals; Drug Combinat

1987
[Reproductive and teratologic effects of long-term exposure to nitrous oxide and halothane in mice].
    Masui. The Japanese journal of anesthesiology, 1986, Volume: 35, Issue:2

    Topics: Abnormalities, Drug-Induced; Anesthesia, Inhalation; Animals; Female; Halothane; Male; Mice; Nitrous

1986
Nitrous oxide during pregnancy.
    Anaesthesia, 1986, Volume: 41, Issue:9

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anesthesia, General; Anesthesia, Obstetrical; Fe

1986
Nitrous oxide in early human pregnancy.
    Anaesthesia, 1986, Volume: 41, Issue:9

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anesthesia, Conduction; Anesthesia, General; Ane

1986
Nitrous oxide and the fetus. A review and the results of a retrospective study of 175 cases of anaesthesia for insertion of Shirodkar suture.
    British journal of anaesthesia, 1986, Volume: 58, Issue:12

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anesthesia, Inhalation; Anesthesia, Obstetrical; Fem

1986
Reproductive and teratogenic effects of nitrous oxide, halothane, isoflurane, and enflurane in Sprague-Dawley rats.
    Anesthesiology, 1986, Volume: 64, Issue:3

    Topics: Abnormalities, Drug-Induced; Anesthesia, Inhalation; Animals; Birth Weight; Body Weight; Cleft Palat

1986
Dangers of chronic exposure to inhalation anaesthetics. Preventive measures.
    Acta anaesthesiologica Belgica, 1973, Volume: 24, Issue:2

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Air Pollution; Anesthesiology; Anesthetics; Anim

1973
Teratology in anesthesia.
    Clinical obstetrics and gynecology, 1974, Volume: 17, Issue:2

    Topics: Abnormalities, Drug-Induced; Anesthesia, Inhalation; Anesthetics; Barbiturates; Bone and Bones; Cycl

1974
Anesthesia for uncomplicated obstetric delivery.
    American family physician, 1974, Volume: 9, Issue:1

    Topics: Abnormalities, Drug-Induced; Adjuvants, Anesthesia; Anesthesia, Conduction; Anesthesia, Epidural; An

1974
Anesthetics as a cause of abortion.
    Fertility and sterility, 1972, Volume: 23, Issue:11

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Embryo, Mammalian; Environmental Exposu

1972
Toxicity of nitrous oxide.
    Annals of the Royal College of Surgeons of England, 1971, Volume: 48, Issue:2

    Topics: Abnormalities, Drug-Induced; Anesthesia, Dental; Animals; Bone Marrow; Bronchitis; Diffusion; Female

1971
Inhalation anaesthesia and analgesia.
    International anesthesiology clinics, 1967,Spring, Volume: 5, Issue:1

    Topics: Abnormalities, Drug-Induced; Analgesia; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthesiol

1967