nitrosochloramphenicol and Hemolysis

nitrosochloramphenicol has been researched along with Hemolysis* in 1 studies

Other Studies

1 other study(ies) available for nitrosochloramphenicol and Hemolysis

Article	Year
Induction of methemoglobin formation by nitroso-chloramphenicol in hemolyzed blood. Research communications in chemical pathology and pharmacology, 1982, Volume: 38, Issue:3 We studied the effects of chloramphenicol (CAP), nitroso-chloramphenicol (NO-CAP) and thiamphenicol (TAP) on methemoglobin (MeHb) formation in vitro in hemolyzed blood. At concentrations of 0.5 to 10 mM CAP and TAP did not have any effect on hemoglobin. On the other hand, NO-CAP at 0.25 to 5 mM caused both time and concentration dependent increase in MeHb formation. The oxidation of hemoglobin was reversible by potassium cyanide. Since MeHb was detected only at NO-CAP concentration 0.25 mM or higher, methemoglobin formation is not a sensitive indication of NO-CAP presence. Topics: Chloramphenicol; Hemolysis; Humans; In Vitro Techniques; Methemoglobin; Thiamphenicol	1982

Article

Year

Induction of methemoglobin formation by nitroso-chloramphenicol in hemolyzed blood.

Research communications in chemical pathology and pharmacology, 1982, Volume: 38, Issue:3

We studied the effects of chloramphenicol (CAP), nitroso-chloramphenicol (NO-CAP) and thiamphenicol (TAP) on methemoglobin (MeHb) formation in vitro in hemolyzed blood. At concentrations of 0.5 to 10 mM CAP and TAP did not have any effect on hemoglobin. On the other hand, NO-CAP at 0.25 to 5 mM caused both time and concentration dependent increase in MeHb formation. The oxidation of hemoglobin was reversible by potassium cyanide. Since MeHb was detected only at NO-CAP concentration 0.25 mM or higher, methemoglobin formation is not a sensitive indication of NO-CAP presence.

Topics: Chloramphenicol; Hemolysis; Humans; In Vitro Techniques; Methemoglobin; Thiamphenicol

1982