nitrosobis(2-oxopropyl)amine has been researched along with Cancer of Pancreas in 248 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 100 (40.32) | 18.7374 |
| 1990's | 99 (39.92) | 18.2507 |
| 2000's | 38 (15.32) | 29.6817 |
| 2010's | 11 (4.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grandhi, BK; Prabhu, S; Thakkar, A; Wang, J | 1 |
| Ishigamori, R; Kamanaka, Y; Kitahashi, T; Komiya, M; Maruyama, T; Mutoh, M; Naka, M; Sato, H; Sugimura, T; Takahashi, M; Wakabayashi, K | 1 |
| Crooks, PA; Holcomb, B; Neelakantan, S; Njoku, V; Ralstin, M; Schmidt, CM; Sweeney, CJ; Wu, H; Yip-Schneider, MT | 1 |
| Furukawa, M; Honoki, K; Tsujino, M; Tsujiuchi, T; Wakabayashi, N; Yamasaki, A; Yoshida, J | 1 |
| Bang, S; Chung, HW; Park, JY; Park, KH; Park, SW; Song, SY; Wen, J | 1 |
| Arjona-Sánchez, A; Cruz, A; Muñoz, Mdel C; Muntané, J; Padillo, FJ; Perea, MD; Ruiz-Rabelo, J; Túnez, I; Vázquez, R | 1 |
| Arjona, A; Montilla, P; Muntané, J; Padillo, J; Perea, D; Ruiz-Rabelo, J; Túnez, I; Vázquez, R | 1 |
| Bergmann, F; El-Ghamari, M; Schmied, BM; Ulrich, A; Weitz, J | 1 |
| Hori, M; Imai, T; Ishigamori, R; Kitahashi, T; Mutoh, M; Sugimura, T; Takahashi, M; Takasu, S; Wakabayashi, K | 1 |
| Ikawa, S; Kitahashi, T; Nakamura, Y; Nomura, Y; Park, EY; Sakamoto, A; Sasabe, S; Sato, K; Shimizu, K; Tsujiuchi, T; Tsutsumi, M | 1 |
| Ma, QS; Pu, Y; Shao, Y; Shen, CY; Wu, CY; Wu, ZS; Yang, ZW; Zeng, NL; Zhang, M; Zhang, XM; Zhou, LS | 1 |
| Fujii, H; Hayakawa, T; Imai, T; Kimura, S; Mutoh, M; Tsuda, K; Umeda, IO; Wakabayashi, K; Yoshimoto, M | 1 |
| Fujii, G; Imai, T; Ishigamori, R; Mutoh, M; Takahashi, M | 1 |
| Inoue, T; Ishii, Y; Matsuo, T; Nakamura, Y; Nishikawa, A; Ogawa, K; Okamoto, S; Okamura, T; Park, EY; Sato, K; Tasaki, M; Umemura, T | 1 |
| Gregor, JI; Guski, H; Jacobi, CA; Kilian, M; Mautsch, I; Schimke, I; Stahlknecht, P; Wenger, FA | 1 |
| Buscail, L; Torrisani, J | 1 |
| Furukawa, F; Hirose, M; Kanki, K; Kawamori, T; Lee, IS; Nishikawa, A; Okazaki, K; Umemura, T; Wakabayashi, K | 1 |
| Brackett, DJ; Hanas, JS; Lane, MM; Lerner, MR; Lightfoot, SA; Postier, RG; Vannarath, R | 1 |
| Akagi, J; Egami, H; Hayashi, N; Ishikawa, S; Kurizaki, T; Ogawa, M; Tamori, Y; Tan, X; Yoshida, N | 1 |
| Drenth, JP; Jansen, JB; Laverman, P; Oyen, WJ; van Kouwen, MC; van Krieken, JH | 1 |
| Nozawa, F; Pour, PM | 1 |
| Gregor, JI; Guski, H; Heukamp, I; Jacobi, CA; Kilian, M; Neumann, A; Schimke, I; Walz, MK; Wenger, FA | 1 |
| Adrian, TE; Bell, RH; Buchler, MW; Ding, XZ; Friess, H; Grippo, P; Hennig, R; Rao, SM; Talamonti, MS | 1 |
| Fujii, H; Hanaoka, M; Honoki, K; Kato, A; Shimizu, K; Tsujiuchi, T | 1 |
| Gregor, JI; Heukamp, I; Jacobi, CA; Kiewert, C; Kilian, M; Kristiansen, G; Schimke, I; Walz, MK; Wenger, FA | 1 |
| Hirose, M; Ishii, Y; Kanki, K; Kitamura, Y; Kuroiwa, Y; Nishikawa, A; Umemura, T | 1 |
| Gao, J; Iatropoulos, MJ; Kashfi, K; Kopelovich, L; Ouyang, N; Rigas, B; Tsioulias, GJ; Williams, JL | 1 |
| Iki, K; Pour, PM | 1 |
| Adachi, T; Fukuda, K; Kanematsu, T; Kitasato, A; Kuroki, T; Mishima, T; Tajima, Y; Tsutsumi, R | 1 |
| Ahlgrimm, M; Gregor, JI; Hanel, M; Heukamp, I; Jacobi, CA; Kilian, M; Kristiansen, G; Ommer, A; Schimke, I; Walz, MK; Wenger, FA | 1 |
| Mutoh, M; Niho, N; Sakano, K; Sato, H; Sugimura, T; Takahashi, M; Takeuchi, Y; Wakabayashi, K; Yamamoto, M | 1 |
| Cruz, A; González, R; Montilla, P; Muñoz-Villanueva, MC; Muntané, J; Padillo, FJ; Perea, MD; Romero, A; Ruiz-Rabelo, JF; Túnez, I; Vázquez, R | 1 |
| Fujii, H; Honoki, K; Itsuzaki, Y; Shimizu, K; Tsujiuchi, T | 1 |
| Donnelly, T; Pour, PM; Stepan, K | 2 |
| Helgeson, AS; Lawson, T; Pour, P | 1 |
| Hayashi, Y; Kokubo, T; Nagase, S; Takahashi, M | 1 |
| Bannasch, P; Ito, N; Moore, MA; Takahashi, M | 1 |
| Lawson, T; Pour, PM | 1 |
| Nagel, D; Pour, P; Salmasi, S; Wallcave, L | 1 |
| Birt, DF; Pour, PM; Salmasi, S | 1 |
| Donnelly, T; Muffly, K; Pour, PM; Stepan, K | 1 |
| Carmack, C; Collias, K; Haberfelde, G; Maset, R; Rinderknecht, H | 1 |
| Birt, DF; Pour, PM; Stepan, KR | 1 |
| Furukawa, F; Hayashi, Y; Kokubo, T; Kurata, Y; Takahashi, M | 1 |
| Patil, K; Pour, PM | 1 |
| Pour, PM; Reber, HA; Stepan, K | 1 |
| Longnecker, DS | 1 |
| Pour, PM; Stepan, K | 1 |
| Birt, D; Gingell, R; Lawson, T; Nagel, D; Pour, PM; Runge, RG; Salmasi, SZ; Wallcave, L | 1 |
| Birt, DF; Davies, MH; Pour, P; Sayed, S | 1 |
| Birt, DF; Götz, U; Pour, PM; Salmasi, SZ | 1 |
| Birt, DF; Pour, PM | 1 |
| Donnelly, T; Pour, PM; Stepan, K; Takahashi, M | 1 |
| Birt, DF; Davies, MH; Pour, PM; Salmasi, S | 1 |
| Curphey, TJ; Kuhlmann, ET; Longnecker, DS; Schaeffer, BK | 1 |
| Donnelly, T; Lawson, T; Pour, PM; Stepan, K | 1 |
| Knutsen, GL; Kovatch, RM; Lijinsky, W; Saavedra, JE | 1 |
| Donnelly, K; Pour, PM; Stepan, K | 2 |
| Hollenberg, PF; Kokkinakis, DM; Rao, MS; Scarpelli, DG | 1 |
| Brown, RA; Duguid, WP; Rosenberg, L | 1 |
| Pour, P; Runge, RG | 1 |
| Rao, MS; Scarpelli, DG; Subbarao, V | 3 |
| Curphey, TJ; Kuhlmann, ET; Longnecker, DS | 1 |
| Gingell, R; Wislocki, P | 1 |
| Flaks, A; Flaks, B; Moore, MA | 2 |
| Rao, MS; Scarpelli, DG | 1 |
| Arai, H; Furukawa, F; Ito, N; Kokubo, T; Kurata, Y; Takahashi, M | 1 |
| Gingell, R; Grandjean, C; Langenbach, R; Lawson, T; Nagel, D; Pour, P; Salmasi, S | 1 |
| Imaoka, S; Ishikawa, O; Mitsuo, M; Nakai, I; Ohigashi, H; Pour, PM; Weide, L | 1 |
| Clapper, ML; Lang, D; Leahy, K; Miknyoczki, S; Ruggeri, BA; Wood, M | 1 |
| Baum, A; Ernst, H; Kamino, K; Son, WC | 1 |
| Appel, MJ; Woutersen, RA | 1 |
| Adrian, TE; Bilchik, AJ; Herrington, MK; Kazakoff, KR; Permert, J; Pour, PM; Zuker, KA | 1 |
| Denda, A; Horiguchi, K; Iimura, K; Kobayashi, E; Konishi, Y; Noguchi, O; Okita, S; Tamura, K; Tsujiuchi, T; Tsutsumi, M | 1 |
| Fujii, K; Hayakawa, T; Kikuchi, M | 1 |
| Chang, KW; Hubchak, S; Laconi, S; Mangold, KA; Scarpelli, DG | 1 |
| Csikós, A; Halmos, G; Lapis, K; Mulchahey, JJ; Neill, JD; Schally, AV; Szende, B; Szepeshazi, K | 1 |
| Furukawa, F; Hayashi, Y; Ikezaki, S; Imazawa, T; Nishikawa, A; Takahashi, M; Yoshimura, H | 1 |
| Adrian, TE; Bilchik, AJ; Herrington, MK; Kazakoff, KR; Permert, J; Pour, PM; Zucker, KA | 1 |
| Hirose, N; Makino, T; Ogawa, T; Sugano, M | 1 |
| Aze, Y; Furukawa, F; Imazawa, T; Nishikawa, A; Sato, M; Takahashi, M; Yoshimura, H | 1 |
| Appel, MJ; van Garderen-Hoetmer, A; Woutersen, RA | 2 |
| Honoki, K; Horiguchi, K; Kobayashi, E; Kondoh, S; Konishi, Y; Noguchi, O; Ohashi, K; Okita, S; Tsujiuchi, T; Tsutsumi, M | 1 |
| Kobayashi, T; Tamura, K; Uchida, E; Yamanaka, N | 1 |
| Chaney, WG; Corra, S; Egami, H; Fujii, H; Hirota, M; Pour, PM; Rizzino, A | 1 |
| Ahrén, B; Andrén-Sandberg, A | 1 |
| Watanapa, P; Williamson, RC | 1 |
| Kokkinakis, DM; Subbarao, V | 1 |
| Bell, RH; Fenoglio-Preiser, CM; McCullough, PJ; Povoski, SP; Sayers, HJ; Zhou, W | 1 |
| Miyazaki, N; Saito, Y; Tomioka, M; Yamamoto, M | 1 |
| Chaney, WG; Hirota, M; Mogaki, M; Pour, PM | 1 |
| Chung, FL; Furukawa, F; Hayashi, Y; Ikezaki, S; Nishikawa, A; Takahashi, M; Tanakamaru, ZY | 1 |
| Bruggink, AH; de Weger, RA; Kobrin, MS; Korc, M; Seifert-Bock, I; van Blokland, WT; van Garderen-Hoetmer, A; Visser, CJ; Woutersen, RA | 1 |
| Foekens, JA; Klijn, JG; van Garderen-Hoetmer, A; Visser, CJ | 1 |
| Chung, FL; Furukawa, F; Hayashi, Y; Ikezaki, S; Nishikawa, A; Takahashi, M; Tanakamaru, Z; Uneyama, C | 1 |
| Kazakoff, K; Pour, PM | 2 |
| Bell, RH; Cualing, HD; Fenoglio-Preiser, CM; Povoski, SP; Yassin, RS | 1 |
| Hiura, A; Satake, K; Tsutsumi, M; Yokomatsu, H | 1 |
| Capellá, G; Cuatrecasas, M; Erill, N; Farré, A; Lluís, F; Pour, PM; Sancho, FJ | 1 |
| Kamano, T; Konishi, Y; Mori, Y; Suda, K; Takada, T; Takahashi, M; Tsutsumi, M; Uchida, T | 1 |
| Appel, MJ; Biemond, I; Lamers, CB; Tang, C; Visser, CJ; Woutersen, RA | 1 |
| Adrian, TE; Bagchi, D; Bagchi, M; Birt, DF; Cardesa, T; Kazakoff, K; Liu, J; Pour, PM | 1 |
| Go, VL; Zhang, J | 1 |
| Borch, K; Chu, M; Rehfeld, JF | 1 |
| Inoue, M; Onda, M; Uchida, E | 1 |
| Borch, K; Chu, M; Kullman, E; Rehfeld, JF | 1 |
| Fienhold, MA; Ikematsu, Y; Kazakoff, K; Liu, G; Pour, PM; Sanger, W; Scheetz, M; Toshkov, I; Weide, L | 1 |
| Baba, M; Iishi, H; Nakaizumi, A; Tatsuta, M; Uehara, H | 1 |
| Konishi, Y; Majima, T; Tsujiuchi, T; Tsunoda, T; Tsutsumi, M | 1 |
| Hiura, A; Satake, K; Tsutsumi, M | 1 |
| Adrian, TE; Cina, RA; Fehsenfeld, DM; Gasslander, T; Herrington, MK; Kazakoff, KR; Pour, PM | 1 |
| Fienhold, MA; Kazakoff, K; Pour, PM | 1 |
| Adrian, TE; Cano, M; Fienhold, MA; Hollingsworth, MA; Ikematsu, Y; Liu, G; Pour, PM; Sanger, W; Tomioka, T; Williamson, JE | 1 |
| Barnett, T; Birt, DF; Blackwood, D; Duysen, E; Nagel, DL; Pour, PM | 1 |
| Konishi, Y; Majima, T; Nishino, H; Tsunoda, T; Tsutsumi, M | 1 |
| Furukawa, F; Imazawa, T; Kasahara, K; Nishikawa, A; Takahashi, M | 1 |
| Konishi, Y; Tsujiuchi, T; Tsutsumi, M | 1 |
| Adrian, TE; Haay, W; Murphy, L; Pour, PM; Schmied, B; Toshkov, I | 1 |
| Adrian, TE; Kazakoff, K; Liu, J; Pour, PM | 1 |
| Batra, S; Hernberg, IS; Liu, G; Moyer, MP; Pour, PM; Sanger, W; Schmied, B | 1 |
| Pour, PM; Schmied, B | 1 |
| Iki, K; Kido, A; Konishi, Y; Motoyama, M; Sakitani, H; Takahama, M; Tatsumi, K; Tsunoda, T; Tsutsumi, M; Yoshimoto, M | 1 |
| Jacobi, CA; Kilian, M; Müller, JM; Wenger, FA; Zieren, HU; Zieren, J | 1 |
| Li, CH; Matsuzaki, H; Pour, PM; Schmied, BM; Ulrich, A | 1 |
| Pour, PM; Schmied, BM | 1 |
| Furukawa, F; Hirose, M; Ikeda, T; Imazawa, T; Kasahara, K; Miyauchi, M; Nakamura, H; Nishikawa, A; Tanakamaru, Z | 1 |
| Iki, K; Konishi, Y; Sasaki, Y; Sugimura, T; Tsujiuchi, T; Tsutsumi, M; Wakabayashi, K; Yoshimoto, M | 1 |
| Ikematsu, Y; Inoue, K; Kanematsu, T; Kitajima, T; Tajima, Y; Tomioka, T | 1 |
| Batra, SK; Matsuzaki, H; Pour, PM; Schmied, BM; Ulrich, A | 1 |
| Furukawa, F; Hirose, M; Lee, IS; Miyauchi, M; Nakamura, H; Nishikawa, A; Son, HY; Takahashi, M | 1 |
| Konishi, Y; Minami, T; Okazaki, Y; Sakita, Y; Tsutsumi, M | 1 |
| Furukawa, F; Hirose, M; Koshimizu, K; Miyauchi, M; Murakami, A; Nakamura, H; Nishikawa, A; Ohigashi, H; Son, HY | 1 |
| Ikematsu, S; Kadomatsu, K; Konishi, Y; Kubozoe, T; Muramatsu, T; Sakitani, H; Sakuma, S; Tsujiuchi, T; Tsutsumi, M; Yoshimoto, M | 1 |
| Furukawa, F; Hirose, M; Ikeda, T; Lee, IS; Miyauchi, M; Nakamura, H; Nishikawa, A; Son, HY | 1 |
| Adrian, TE; Herrington, M; Kazakoff, K; Permert, J; Pour, PM | 1 |
| Dressler, H; Guski, H; Jacobi, CA; Kilian, M; Müller, JM; Wenger, FA | 1 |
| Guski, H; Jacobi, CA; Kilian, M; Mautsch, I; Müller, JM; Saul, GJ; Schimke, I; Wenger, FA | 1 |
| Konishi, Y; Kubozoe, T; Murata, N; Sasaki, Y; Tsujiuchi, T; Tsunoda, T; Tsutsumi, M | 1 |
| Guski, H; Jacobi, CA; Kilian, M; Mautsch, I; Müller, JM; Peter, FJ; Schimke, I; Steiert, A; Wenger, FA | 1 |
| Guski, H; Jacobi, CA; Kilian, M; Proske, JM; Schimke, I; Wenger, FA | 1 |
| Guski, H; Jacobi, CA; Kilian, M; Müller, JM; Ridders, J; Schimke, I; Stahlknecht, P; Wenger, FA | 1 |
| Beppu, H; Chihara, T; Furukawa, F; Hirose, M; Kuzuya, H; Lee, IS; Nishikawa, A; Shimpo, K | 1 |
| Braumann, C; Guski, H; Jacobi, CA; Kilian, M; Neumann, A; Peter, FJ; Ridders, J; Wenger, FA | 1 |
| Althoff, J; Krüger, FW; Mohr, U; Pour, P | 1 |
| Pour, P; Rao, MS | 1 |
| Brunk, G; Gingell, R; Nagel, D; Pour, P | 1 |
| Gingell, R; Nagel, D; Pour, P; Runge, R; Salmasi, S; Stepan, K; Wallcave, L | 1 |
| Pour, P; Runge, RG; Salmasi, SZ | 1 |
| Donnelly, T; Pour, P; Runge, R; Takahashi, M | 1 |
| Pour, PM; Runge, RG; Salmasi, SZ | 1 |
| Pour, P; Runge, R; Takahashi, M | 1 |
| Althoff, J; Donnelly, T; Pour, P; Takahashi, M | 1 |
| Althoff, J; Krüger, F; Mohr, U; Pour, P; Schmähl, D | 1 |
| Furukawa, F; Imazawa, T; Mitsumori, K; Nishikawa, A; Takahashi, M; Yoshimura, H | 1 |
| Enami, T; Furukawa, F; Hayashi, Y; Imaida, K; Mitsui, M; Nishikawa, A; Takahashi, M | 1 |
| Furukawa, F; Hayashi, Y; Imaida, K; Imazawa, T; Sato, M; Shinoda, K; Takahashi, M; Yoshimura, H | 1 |
| Chaney, WG; Hirota, M; Pour, PM; Tempero, MA | 1 |
| Barr, H; Bedwell, J; Bown, SG; Chatlani, PT; MacRobert, AJ; Nuutinen, PJ; Toda, N | 1 |
| Koga, A; Kosahara, K; Makino, T; Nakayama, F; Ogawa, T | 1 |
| Bell, RH; Pour, PM; Povoski, SP; Sayers, HJ; Zhou, W | 1 |
| Abad, MM; Arévalo, M; Bullón, A; Carrascal, E; Muñoz, E; Paz-Bouza, JI | 1 |
| Cerny, WL; Mangold, KA; Scarpelli, DG | 2 |
| Chaney, WG; Egami, H; Pour, PM; Takiyama, Y | 1 |
| Lapis, K; Schally, AV; Szepeshazi, K | 1 |
| Cai, RZ; Milovanovic, S; Radulovic, S; Schally, AV; Szepeshazi, K; Szoke, B | 1 |
| Bullón, A; Carrascal, E; Mar Abad, M; Muñoz, E; Paz-Bouza, JI | 1 |
| Bakker, GH; de Jong, FH; Foekens, JA; Klijn, JG; Meijers, M; van Garderen-Hoetmer, A; Woutersen, RA | 2 |
| Jansen, JB; Lamers, CB; Meijers, M; Rovati, LC; van Garderen-Hoetmer, A; Woutersen, RA | 3 |
| Amanuma, T; Denda, A; Kondoh, S; Konishi, Y; Mizumoto, K; Tsujiuchi, T; Tsutsumi, M | 1 |
| Pour, PM | 4 |
| Furukawa, F; Hayashi, Y; Imaida, K; Imazawa, T; Okamiya, H; Sato, M; Shinoda, K; Takahashi, M | 1 |
| Furukawa, F; Hayashi, Y; Imaida, K; Takahashi, M | 1 |
| Sato, T | 1 |
| Egami, H; Pour, PM; Takiyama, Y | 2 |
| Kokkinakis, DM | 1 |
| Carter, DC; Haddock, G; Harrison, DJ | 1 |
| Makino, T; Mizumoto, K; Nakayama, F; Ogawa, T | 1 |
| Amanuma, T; Denda, A; Kondo, S; Konishi, Y; Maruyama, H; Nakae, D; Tsujiuchi, T; Tsutsumi, M | 1 |
| Schally, AV; Zalatnai, A | 3 |
| Carlson, K; Kazakoff, K; Pour, PM | 1 |
| Groot, K; Lapis, K; Schally, AV; Srkalovic, G; Szende, B | 1 |
| Amanuma, T; Kitazawa, S; Konishi, Y; Maruyama, H; Mizumoto, K; Tsutsumi, M | 1 |
| Chaney, W; Egami, H; Fujii, H; Pelling, J; Pour, P | 1 |
| Furukawa, F; Hasegawa, R; Hayashi, Y; Imaida, K; Sato, H; Takahashi, M; Toyoda, K | 1 |
| Denda, A; Kitazawa, S; Konishi, Y; Mizumoto, K; Tsutsumi, M | 1 |
| Birt, DF; Dwork, E; Hanna, T; Julius, AD; Pour, PM; White, LT | 1 |
| Hioki, K; Kise, Y; Kogata, M; Takada, H; Uetsuji, S; Yamamoto, M; Yamamura, M | 1 |
| Bell, RH; Ray, MB | 1 |
| Furukawa, F; Hayashi, Y; Imaida, K; Nagase, S; Takahashi, M | 1 |
| Bax, J; Scherer, E; Van Garderen-Hoetmer, A; Woutersen, RA | 3 |
| Bell, RH; McCullough, PJ; Pour, PM; Ray, MB; Sayers, HJ | 1 |
| Denda, A; Ito, S; Kitazawa, S; Konishi, Y; Mizumoto, K; Takashima, Y; Tsutsumi, M | 1 |
| Fekete, M; Schally, AV; Zalatnai, A | 1 |
| Bell, RH; Pour, PM | 2 |
| Comaru-Schally, AM; Fekete, M; Schally, AV; Zalatnai, A | 1 |
| Furukawa, F; Hayashi, Y; Imai, K; Saito, Y; Suzuki, T; Takahashi, M; Toyo'oka, T; Uzu, S | 1 |
| Britton, DC; Chester, JF; Lever, JV; Norris, MA; Turnbull, AR | 1 |
| Kokkinakis, DM; Scarpelli, DG | 1 |
| Denda, A; Ito, S; Kitazawa, S; Konishi, Y; Mizumoto, K; Tsutsumi, M | 1 |
| Birt, DF; Julius, AD; Pour, PM; White, LT | 1 |
| Birt, DF; Julius, AD; Lawson, T; Pour, PM; Runice, CE; White, LT | 1 |
| Donnelly, T; Helgeson, S; Lawson, T; Pour, PM; Stepan, K | 1 |
| Bannasch, P; Hacker, HJ; Ito, N; Moore, MA; Satoh, T | 1 |
| Archer, MC; Chan, AM; Zucker, PF | 1 |
| Bax, J; Feringa, AW; Scherer, E; van Garderen-Hoetmer, A; Woutersen, RA | 1 |
| Bell, RH; McCullough, PJ; Pour, PM | 1 |
| Bell, RH; Brackett, K; Chen, IW; Joffe, SN; Schroder, T; Sperling, M | 1 |
| Chester, JF; Gaissert, HA; Malt, RA; Ross, JS | 2 |
| Furukawa, F; Hasegawa, R; Hayashi, Y; Jang, JJ; Sato, H; Takahashi, M; Toyoda, K | 1 |
| Denda, A; Konishi, Y; Mizumoto, K; Tsutsumi, M | 1 |
| Birt, DF; Julius, AD; Runice, CE; Salmasi, S | 1 |
| Carter, DC; Howatson, AG | 2 |
| Carré-Llopis, A; Eriguchi, M; Escribano, J; Orbach-Arbouys, S | 1 |
| Ito, S; Katsuragi, M; Konishi, Y; Makino, T; Obara, T; Ohishi, G; Uchida, H; Ura, H; Yoshiya, K | 1 |
| Carre-Llopis, A; de Vaux St Cyr, C; Escribano, MJ; Zuinghedau, J | 1 |
| Brown, LF; Chester, JF; Dvorak, HF; Malt, RA | 1 |
| Curphey, TJ; Kuhlmann, ET; Longnecker, DS; Neff, RK; Roebuck, BD | 1 |
| Birt, DF; Bresnick, E; Pelling, JC; Pour, PM; Schweickert, L; Tibbels, MG | 1 |
| Longnecker, DS; van Garderen-Hoetmer, A; Woutersen, RA | 1 |
| Carre-Llopis, A; Escribano, MJ; Loridon-Rosa, B | 1 |
| Fischer, M; Lawson, TA; Lewis, R; Nagel, DL; Stansbury, K; Stepan, K | 1 |
| Furukawa, F; Hasegawa, R; Hayashi, Y; Naito, Z; Takahashi, M; Toyoda, K | 1 |
| Hasdai, A; Liener, IE | 1 |
| Burnett, D; Pour, PM; Uchida, E | 1 |
| Birt, DF; Patil, K; Pour, PM | 1 |
8 review(s) available for nitrosobis(2-oxopropyl)amine and Cancer of Pancreas
| Article | Year |
|---|---|
Involvement of inflammatory factors in pancreatic carcinogenesis and preventive effects of anti-inflammatory agents.
Topics: Adipokines; Animals; Anti-Inflammatory Agents; Carcinogens; Cricetinae; Cyclooxygenase 2; Diabetes Mellitus, Type 2; Gene Expression Regulation, Neoplastic; Humans; Hyperlipidemias; Inflammation Mediators; Neoplasm Proteins; Neoplasms, Experimental; Nitric Oxide Synthase Type II; Nitrosamines; Obesity; Pancreatic Neoplasms; Pancreatitis; Risk Factors | 2013 |
[Molecular pathways of pancreatic carcinogenesis].
Topics: Adenocarcinoma; Animals; Carcinogens; Cell Differentiation; Cell Division; Codon; Cricetinae; Genes, ras; Humans; Mesocricetus; Mutation; Nitrosamines; Pancreatic Neoplasms | 2002 |
Experimental pancreatic hyperplasia and neoplasia: effects of dietary and surgical manipulation.
Topics: Animals; Cricetinae; Diet; Disease Models, Animal; Energy Intake; Esters; Flour; Gabexate; Glycine max; Guanidines; Humans; Hyperplasia; Mice; Nitrosamines; Pancreas; Pancreatic Diseases; Pancreatic Neoplasms; Rats | 1993 |
High fat diet, lipid peroxidation, and pancreatic carcinogenesis.
Topics: Animals; Arachidonic Acid; Carcinogens; Dietary Fats; Fish Oils; Humans; Lipid Peroxidation; Nitrosamines; Pancreatic Neoplasms; Prostaglandins | 1996 |
Mechanistic analysis of pancreatic ductal carcinogenesis in hamsters.
Topics: Adenocarcinoma; Animals; Carcinogens; Cricetinae; Disease Models, Animal; Hyperplasia; Mesocricetus; Mutation; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Pressure | 1998 |
The link between exocrine pancreatic cancer and the endocrine pancreas.
Topics: Adenocarcinoma; Animals; Carcinogens; Cell Differentiation; Cricetinae; Dietary Fats; Disease Models, Animal; Humans; Islets of Langerhans; Mesocricetus; Neoplasms, Experimental; Neoplastic Stem Cells; Nitrosamines; Pancreatic Neoplasms | 1999 |
Modification of tumor development in the pancreas.
Topics: 4-Hydroxyaminoquinoline-1-oxide; Aging; Animals; Azaserine; Cocarcinogenesis; Diet; Disease Models, Animal; Ethionine; Gonadal Steroid Hormones; Nitrosamines; Pancreatic Neoplasms; Precancerous Conditions; Vitamins | 1991 |
Possible enhancement of carcinogenesis by selenium in an animal tumor model.
Topics: Animals; Cricetinae; Disease Models, Animal; Nitrosamines; Pancreatic Neoplasms; Selenium | 1989 |
240 other study(ies) available for nitrosobis(2-oxopropyl)amine and Cancer of Pancreas
| Article | Year |
|---|---|
A novel combinatorial nanotechnology-based oral chemopreventive regimen demonstrates significant suppression of pancreatic cancer neoplastic lesions.
Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aspirin; Carcinogens; Cell Line, Tumor; Cricetinae; Curcumin; Disease Models, Animal; Disease Progression; Drug Delivery Systems; Immunohistochemistry; In Situ Nick-End Labeling; Isothiocyanates; Lipids; Male; Mesocricetus; Nanoparticles; Nitrosamines; Pancreatic Neoplasms; Proliferating Cell Nuclear Antigen; Sulfoxides | 2013 |
Increased expression of inducible nitric oxide synthase (iNOS) in N-nitrosobis(2-oxopropyl)amine-induced hamster pancreatic carcinogenesis and prevention of cancer development by ONO-1714, an iNOS inhibitor.
Topics: Amidines; Animals; Carcinogens; Cell Line, Tumor; Cricetinae; DNA Primers; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 2-Ring; Humans; Mesocricetus; Nitric Oxide Synthase Type II; Nitrosamines; Pancreatic Neoplasms; RNA, Messenger | 2008 |
Effect of celecoxib and the novel anti-cancer agent, dimethylamino-parthenolide, in a developmental model of pancreatic cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Cell Proliferation; Chemokines, C; Cricetinae; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Female; Ki-67 Antigen; Mesocricetus; Mucins; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Nitrosamines; Pancreatic Neoplasms; Pyrazoles; Sesquiterpenes; Sulfonamides; Time Factors | 2008 |
Mutations of LKB1 gene in pancreatic ductal adenocarcinomas induced by N-nitrosobis(2-oxopropyl)amine in hamsters.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cricetinae; Female; Mesocricetus; Mutagens; Nitrosamines; Pancreatic Neoplasms; Polymorphism, Single-Stranded Conformational; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Oct4 and Nanog expression is associated with early stages of pancreatic carcinogenesis.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Transformation, Neoplastic; Cricetinae; Genes, ras; Homeodomain Proteins; Humans; Mutation; Nanog Homeobox Protein; Nitrosamines; Octamer Transcription Factor-3; Pancreatic Neoplasms | 2010 |
Effects of capecitabine and celecoxib in experimental pancreatic cancer.
Topics: Animals; Capecitabine; Celecoxib; Cricetinae; Deoxycytidine; Fluorouracil; Lipid Peroxidation; Lipid Peroxides; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Pyrazoles; Sulfonamides | 2010 |
Improvement of capecitabine antitumoral activity by melatonin in pancreatic cancer.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antioxidants; Capecitabine; Cricetinae; Deoxycytidine; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Lipid Peroxides; Male; Melatonin; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Prodrugs | 2011 |
Islet cells contribute to pancreatic carcinogenesis in an animal model.
Topics: Animals; Biotransformation; Carcinoma, Pancreatic Ductal; Cell Transformation, Neoplastic; Cricetinae; Cytochrome P-450 Enzyme System; Disease Models, Animal; Female; Immunohistochemistry; Islets of Langerhans; Islets of Langerhans Transplantation; Isoenzymes; Mice; Mice, SCID; Nitrosamines; Pancreatic Neoplasms; Time Factors; Transplantation, Heterologous | 2011 |
Enhancement of carcinogenesis and fatty infiltration in the pancreas in N-nitrosobis(2-oxopropyl)amine-treated hamsters by high-fat diet.
Topics: Adenocarcinoma; Adipokines; Animals; Blood Glucose; Body Weight; Carcinogenicity Tests; Carcinoma, Pancreatic Ductal; Cell Transformation, Neoplastic; Cricetinae; Diet, High-Fat; Female; Gene Expression; Insulin; Lipids; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2011 |
Ingestion of proteoglycan fraction from shark cartilage increases serum inhibitory activity against matrix metalloproteinase-9 and suppresses development of N-nitrosobis(2-oxopropyl)amine-induced pancreatic duct carcinogenesis in hamster.
Topics: Animals; Cartilage; Cricetinae; Enzyme Inhibitors; Female; Matrix Metalloproteinase Inhibitors; Mesocricetus; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Proteoglycans; Sharks | 2012 |
Magnetic resonance imaging for pancreatic ductal adenocarcinomas induced by N-nitrosobis (2-oxopropyl) amine in Syrian golden hamsters.
Topics: Abdomen; Animals; Carcinogens; Carcinoma, Pancreatic Ductal; Cricetinae; Female; Magnetic Resonance Imaging; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Radiography; Random Allocation; Reproducibility of Results; Sensitivity and Specificity; Tumor Burden | 2012 |
In vivo SPECT imaging with 111In-DOTA-c(RGDfK) to detect early pancreatic cancer in a hamster pancreatic carcinogenesis model.
Topics: Animals; Autoradiography; Cricetinae; Disease Models, Animal; Early Detection of Cancer; Female; Fluorodeoxyglucose F18; Inflammation; Mice; Nitrosamines; Organometallic Compounds; Pancreatic Neoplasms; Peptides, Cyclic; Tomography, Emission-Computed, Single-Photon | 2012 |
Chemopreventive effects of 4-methylthio-3-butenyl Isothiocyanate (Raphasatin) but not curcumin against pancreatic carcinogenesis in hamsters.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Carcinogens; Cricetinae; Curcumin; Diet; Hyperplasia; Isothiocyanates; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms | 2013 |
Influence of conjugated vs. conventional linoleic acid on liver metastasis and hepatic lipidperoxidation in BOP-induced pancreatic cancer in Syrian hamster.
Topics: Animals; Cricetinae; Dietary Fats, Unsaturated; Glutathione Peroxidase; Linoleic Acids; Lipid Peroxidation; Liver; Liver Neoplasms; Nitrosamines; Pancreatic Neoplasms; Superoxide Dismutase | 2002 |
A cyclooxygenase-2 inhibitor, nimesulide, inhibits postinitiation phase of N-nitrosobis(2-oxopropyl)amine-induced pancreatic carcinogenesis in hamsters.
Topics: Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Cricetinae; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Progression; Isoenzymes; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Proliferating Cell Nuclear Antigen; Prostaglandin-Endoperoxide Synthases; Sulfonamides | 2003 |
DNA ploidy and markovian analysis of neoplastic progression in experimental pancreatic cancer.
Topics: Adenocarcinoma; Animals; Carcinogens; Cricetinae; DNA, Neoplasm; Female; Image Cytometry; Markov Chains; Mesocricetus; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Ploidies; Precancerous Conditions | 2003 |
Identification of genes related to invasion and metastasis in pancreatic cancer by cDNA representational difference analysis.
Topics: 1-Phosphatidylinositol 4-Kinase; Amino Acid Sequence; Animals; Apoptosis; Blotting, Northern; Carcinogens; Cell Line, Tumor; Cell Movement; Cell Survival; Cricetinae; DNA Fragmentation; DNA, Complementary; Enzyme Inhibitors; Humans; MAP Kinase Kinase 2; Mesocricetus; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Metastasis; Nitrosamines; Nucleic Acid Hybridization; Pancreatic Neoplasms; Protein-Tyrosine Kinases; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid | 2003 |
FDG-PET in the detection of early pancreatic cancer in a BOP hamster model.
Topics: Animals; Cricetinae; Disease Models, Animal; Fluorodeoxyglucose F18; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Positron-Emission Tomography | 2005 |
Pancreatic hepatocellular tumor.
Topics: Albumins; Animals; Antigens, Surface; Carcinogens; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cricetinae; Disease Models, Animal; Female; Hepatocytes; Immunoenzyme Techniques; Islets of Langerhans; Liver Neoplasms; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms | 2005 |
Effects of the antioxidative vitamins A, C and E on liver metastasis and intrametastatic lipid peroxidation in BOP-induced pancreatic cancer in Syrian hamsters.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Carcinoma, Pancreatic Ductal; Cricetinae; Disease Models, Animal; Glutathione Peroxidase; Lipid Peroxidation; Liver Neoplasms; Male; Mesocricetus; Neoplasm Metastasis; Nitrosamines; Pancreatic Neoplasms; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vitamin A; Vitamin E | 2005 |
5-Lipoxygenase, a marker for early pancreatic intraepithelial neoplastic lesions.
Topics: Adenocarcinoma; Animals; Arachidonate 5-Lipoxygenase; Biomarkers, Tumor; Carcinogens; Carcinoma in Situ; Cell Growth Processes; Chronic Disease; Cricetinae; Humans; Immunohistochemistry; Lipoxygenase Inhibitors; Mice; Mice, Transgenic; NIH 3T3 Cells; Nitrosamines; Pancreatic Neoplasms; Pancreatitis; Quinolines | 2005 |
Reduced expression of the E-cadherin gene and its aberrant DNA methylation in hamster pancreatic tumors.
Topics: Adenocarcinoma; Animals; Base Sequence; Cadherins; Carcinogens; Cricetinae; DNA Methylation; DNA, Neoplasm; Female; Mesocricetus; Molecular Sequence Data; Nitrosamines; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction | 2005 |
Does enteral nutrition of dietary polyunsaturated fatty acids promote oxidative stress and tumour growth in ductal pancreatic cancer? Experimental trial in Syrian Hamster.
Topics: Animals; Carcinogens; Carcinoma, Pancreatic Ductal; Cricetinae; Dietary Fats, Unsaturated; Docosahexaenoic Acids; Eicosapentaenoic Acid; Enteral Nutrition; Fatty Acids, Unsaturated; Fish Oils; Glutathione Peroxidase; Linoleic Acid; Male; Mesocricetus; Nitrosamines; Oleic Acid; Olive Oil; Oxidative Stress; Pancreas; Pancreatic Neoplasms; Plant Oils; Random Allocation; Soybean Oil; Superoxide Dismutase; Survival Rate; Thiobarbituric Acid Reactive Substances; Triglycerides | 2006 |
Protective effects of benzyl isothiocyanate and sulforaphane but not resveratrol against initiation of pancreatic carcinogenesis in hamsters.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Cricetinae; Cyclooxygenase 2; Diet; Injections, Subcutaneous; Isothiocyanates; Male; Membrane Proteins; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms; Resveratrol; Stilbenes; Sulfoxides; Thiocyanates | 2006 |
Nitric oxide-donating aspirin prevents pancreatic cancer in a hamster tumor model.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Aspirin; Carcinogens; Cell Growth Processes; Cricetinae; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Female; Mesocricetus; NF-kappa B; Nitric Oxide Donors; Nitrosamines; Pancreas; Pancreatic Neoplasms | 2006 |
Expression of Oct4, a stem cell marker, in the hamster pancreatic cancer model.
Topics: Animals; Antibodies, Monoclonal; Biomarkers, Tumor; Cell Nucleus; Cricetinae; Cytoplasm; Disease Models, Animal; Early Diagnosis; Immunohistochemistry; Male; Nitrosamines; Octamer Transcription Factor-3; Pancreas; Pancreatic Neoplasms; Stem Cells | 2006 |
Bile-reflux into the pancreatic ducts is associated with the development of intraductal papillary carcinoma in hamsters.
Topics: Adenocarcinoma; Animals; Bile Acids and Salts; Bile Reflux; Carcinogens; Carcinoma, Pancreatic Ductal; Carcinoma, Papillary; Cell Division; Cholecystostomy; Common Bile Duct; Cricetinae; Disease Models, Animal; Duodenostomy; Epithelial Cells; Female; Mesocricetus; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Proliferating Cell Nuclear Antigen; Sphincter of Oddi Dysfunction | 2006 |
Matrix metalloproteinase inhibitor RO 28-2653 decreases liver metastasis by reduction of MMP-2 and MMP-9 concentration in BOP-induced ductal pancreatic cancer in Syrian Hamsters: inhibition of matrix metalloproteinases in pancreatic cancer.
Topics: Animals; Carcinogens; Carcinoma, Pancreatic Ductal; Cricetinae; Disease Models, Animal; Liver Neoplasms; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Piperazines; Protease Inhibitors; Pyrimidines | 2006 |
Suppression of N-nitrosobis(2-oxopropyl)amine-induced pancreatic carcinogenesis in hamsters by pioglitazone, a ligand of peroxisome proliferator-activated receptor gamma.
Topics: Animals; Antineoplastic Agents; Carcinogens; Cricetinae; Female; Hyperlipidemias; Ligands; Lipoprotein Lipase; Mesocricetus; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Nitrosamines; Pancreatic Neoplasms; Pioglitazone; PPAR gamma; Rats; Rats, Inbred F344; Rats, Wistar; Thiazolidinediones | 2007 |
Beneficial properties of melatonin in an experimental model of pancreatic cancer.
Topics: Animals; Antioxidants; Body Weight; Cricetinae; Disease Models, Animal; Lipid Peroxides; Male; Melatonin; Nitrosamines; Pancreatic Neoplasms | 2007 |
Reduced expression of the Rassf1a gene and its aberrant DNA methylation in pancreatic duct adenocarcinomas induced by N-nitrosobis(2-oxopropyl)amine in hamsters.
Topics: Adenocarcinoma; Animals; Base Sequence; Carcinogens; Cricetinae; DNA Methylation; DNA Primers; Female; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Proteins | 2008 |
Modification of pancreatic carcinogenesis in the hamster model. 7. Inhibitory effect of bethanechol chloride.
Topics: Animals; Bethanechol; Bethanechol Compounds; Carcinoma in Situ; Cricetinae; Female; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms | 1983 |
Exocrine pancreatic secretion in the Syrian golden hamster Mesocricetus auratus--III. Effects of carcinogen administration and development of pancreas cancer.
Topics: Animals; Carcinogens; Cholecystokinin; Cricetinae; Female; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Secretin; Sex Factors | 1984 |
Changes of amylase during experimental pancreatic carcinogenesis in hamsters.
Topics: Adenocarcinoma; Amylases; Animals; Cricetinae; Female; Isoenzymes; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1981 |
Early lesions during pancreatic carcinogenesis induced in Syrian hamster by DHPN or DOPN. I. Histologic, histochemical and radioautographic findings.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cricetinae; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreas; Pancreatic Neoplasms; Staining and Labeling | 1983 |
Modification of pancreatic carcinogenesis in the hamster model. XV. Preventive effect of nicotinamide.
Topics: Adenoma; Animals; Carcinogens; Carcinoma; Cricetinae; Female; Male; Mesocricetus; Niacinamide; Nitrosamines; Pancreatic Neoplasms | 1984 |
Induction of local epidermal papillomas and carcinoma by selected nitrosamines.
Topics: Adenocarcinoma; Adenoma, Bile Duct; Animals; Bile Duct Neoplasms; Carcinoma; Cricetinae; Female; Head and Neck Neoplasms; Liver Neoplasms; Mesocricetus; Nitrosamines; Nose Neoplasms; Pancreatic Neoplasms; Papilloma; Skin Neoplasms | 1980 |
Enhancement of experimental pancreatic cancer in Syrian golden hamsters by dietary fat.
Topics: Adenoma; Animals; Carcinoma, Intraductal, Noninfiltrating; Cricetinae; Dietary Fats; Female; Lipomatosis; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Sex Factors | 1981 |
Modification of pancreatic carcinogenesis in the hamster model. 2. The effect of partial pancreatectomy.
Topics: Animals; Carcinoma, Intraductal, Noninfiltrating; Cell Division; Cricetinae; Female; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreas; Pancreatectomy; Pancreatic Neoplasms; Probability; Regeneration; Time Factors | 1983 |
Pancreatic secretory abnormalities precede appearance of tumors of the pancreas in hamsters treated with bis-(2-oxopropyl)-N-nitrosamine.
Topics: Age Factors; Animals; Carcinoma, Intraductal, Noninfiltrating; Chymotrypsin; Cricetinae; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreas; Pancreatic Elastase; Pancreatic Juice; Pancreatic Neoplasms; Precancerous Conditions; Trypsin | 1983 |
Interaction of dietary fat and protein on pancreatic carcinogenesis in Syrian golden hamsters.
Topics: Adenoma, Islet Cell; Animals; Carcinogens; Cricetinae; Diet; Dietary Fats; Dietary Proteins; Energy Intake; Hyperplasia; Insulinoma; Lipoma; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms | 1983 |
Effect of dibutyltin dichloride on incidence of pancreatic adenocarcinoma induced in hamsters by a single dose of N-nitrosobis(2-oxopropyl)amine.
Topics: Animals; Carcinogens; Carcinoma, Intraductal, Noninfiltrating; Cricetinae; Female; Intubation, Gastrointestinal; Mesocricetus; Nitrosamines; Organotin Compounds; Pancreatic Neoplasms; Sarcoma, Experimental | 1983 |
Modification of pancreatic carcinogenesis in the hamster model. X. Effect of streptozotocin.
Topics: Adenoma, Islet Cell; Animals; Carcinoma, Intraductal, Noninfiltrating; Cocarcinogenesis; Cricetinae; Disease Models, Animal; Drug Synergism; Female; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Papilloma; Probability; Streptozocin | 1983 |
Modification of pancreatic carcinogenesis in the hamster model. XII. Dose-related effect of ethanol.
Topics: Animals; Carcinoma, Intraductal, Noninfiltrating; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Female; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Papilloma; Time Factors | 1983 |
Lesions induced in rodent pancreas by azaserine and other pancreatic carcinogens.
Topics: Animals; Azaserine; Carcinogens; Cell Transformation, Neoplastic; Cricetinae; Nitrosamines; Nitrosourea Compounds; Pancreatic Neoplasms; Rats; Rats, Inbred Lew | 1984 |
Modification of pancreatic carcinogenesis in the hamster model. VIII. Inhibitory effect of exogenous insulin.
Topics: Animals; Cricetinae; Insulin; Islets of Langerhans; Mesocricetus; Nitrosamines; Pancreatic Neoplasms | 1984 |
Current knowledge of pancreatic carcinogenesis in the hamster and its relevance to the human disease.
Topics: Animals; Carcinogens; Cricetinae; Dietary Fats; Humans; Mesocricetus; Morpholines; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms; Streptozocin; Structure-Activity Relationship | 1981 |
Sex differences in the effects of retinoids on carcinogenesis by N-nitrosobis(2-oxopropyl)amine in Syrian hamsters.
Topics: Animals; Carcinoma; Cricetinae; Female; Fenretinide; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms; Sex Factors; Tretinoin | 1981 |
Modifying factors in pancreatic carcinogenesis in the hamster model. I. Effect of protein-free diet fed during the early stages of carcinogenesis.
Topics: Animals; Cricetinae; Dietary Proteins; Female; Gallbladder Neoplasms; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms | 1983 |
Modifying factors in pancreatic carcinogenesis in the hamster model. IV. Effects of dietary protein.
Topics: Animals; Body Weight; Carcinogens; Cricetinae; Diet; Dietary Proteins; Energy Intake; Female; Hyperplasia; Lipoma; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1983 |
Modification of pancreatic carcinogenesis in the hamster model. IX. Effect of pancreatitis.
Topics: Acute Disease; Animals; Carcinogens; Chronic Disease; Cricetinae; Female; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreas; Pancreatic Neoplasms; Pancreatitis | 1983 |
Lack of inhibition by retinoids of bis(2-oxopropyl)nitrosamine-induced carcinogenesis in Syrian hamsters.
Topics: Animals; Body Weight; Cricetinae; Dose-Response Relationship, Drug; Female; Isomerism; Isotretinoin; Male; Mesocricetus; Neoplasms; Nitrosamines; Pancreatic Neoplasms; Sex Factors; Tretinoin | 1983 |
Experimental induction of pancreatic carcinomas in the hamster with N delta-(N-methyl-N-nitrosocarbamoyl)-L-ornithine.
Topics: Animals; Carcinoma; Cricetinae; DNA, Neoplasm; DNA, Single-Stranded; Dose-Response Relationship, Drug; Female; Male; Nitrosamines; Nitrosourea Compounds; Pancreas; Pancreatic Neoplasms | 1983 |
Modification of pancreatic carcinogenesis in the hamster model. XI. Inhibitory effect of pilocarpine hydrochloride.
Topics: Animals; Carcinogens; Cricetinae; Female; Injections, Subcutaneous; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Pilocarpine | 1984 |
Comparison of the carcinogenic effectiveness of N-nitrosobis(2-hydroxypropyl)amine, N-nitrosobis(2-oxopropyl)amine, N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine, and N-nitroso-2,6-dimethylmorpholine in Syrian hamsters.
Topics: Animals; Carcinogens; Cricetinae; Female; Liver Neoplasms; Lung Neoplasms; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Nitroso Compounds; Pancreatic Neoplasms; Structure-Activity Relationship | 1984 |
Modification of pancreatic carcinogenesis in the hamster model. 5. Effect of partial pancreatico-colostomy.
Topics: Animals; Bile Reflux; Biliary Tract Diseases; Carcinogens; Colostomy; Cricetinae; Female; Male; Mesocricetus; Models, Biological; Nitrosamines; Pancreatic Fistula; Pancreatic Neoplasms | 1983 |
Metabolism of pancreatic carcinogens N-nitroso-2,6-dimethylmorpholine and N-nitrosobis(2-oxopropyl)amine by microsomes and cytosol of hamster pancreas and liver.
Topics: Animals; Biotransformation; Carcinogens; Cricetinae; Cytosol; Kinetics; Liver; Male; Mesocricetus; Microsomes; Microsomes, Liver; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1983 |
Modification of pancreatic carcinogenesis in the hamster model. 6. The effect of ductal ligation and excision.
Topics: Animals; Cricetinae; Disease Models, Animal; Hyperplasia; Ligation; Mesocricetus; Mitosis; Nitrosamines; Pancreatectomy; Pancreatic Ducts; Pancreatic Neoplasms | 1983 |
Development of experimental cancer in the head of the pancreas by surgical induction of tissue injury.
Topics: Animals; Carcinoma; Constriction; Cricetinae; Disease Models, Animal; Female; Hyperplasia; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Ribonucleases | 1984 |
Blood group specificity of pancreatic tumor mucin.
Topics: Adenocarcinoma; Agglutinins; Animals; Blood Group Antigens; Cricetinae; Fluorescent Antibody Technique; Immunodiffusion; Mesocricetus; Mucins; Nitrosamines; Pancreatic Neoplasms; Rabbits | 1980 |
Modification of pancreatic carcinogenesis in the hamster model. 3. Inhibitory effect of alloxan.
Topics: Alloxan; Animals; Blood Glucose; Cricetinae; Female; Gallbladder Neoplasms; Injections, Subcutaneous; Male; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms | 1983 |
Augmentation of carcinogenesis by N-nitrosobis(2-oxopropyl)amine administered during S phase of the cell cycle in regenerating hamster pancreas.
Topics: Animals; Cricetinae; Interphase; Male; Neoplasms, Experimental; Nitrosamines; Pancreas; Pancreatic Neoplasms; Regeneration | 1983 |
Effects of four retinoids in N-nitrosobis(2-oxopropyl)amine-treated hamsters.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinoma in Situ; Cricetinae; Diet; Female; Liver Neoplasms; Lung Neoplasms; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Organ Size; Pancreatic Neoplasms; Sex Factors; Vitamin A | 1983 |
Mutagenicity of several pancreatic carcinogenic derivatives of N-nitrosodipropylamine in the Ames assay.
Topics: Animals; Biotransformation; Cricetinae; Drug Evaluation, Preclinical; Microsomes, Liver; Morpholines; Mutagens; Nitrosamines; Pancreatic Neoplasms; Salmonella typhimurium; Structure-Activity Relationship | 1980 |
Ultrastructural analysis of pancreatic carcinogenesis. VI. Early changes in hamster acinar cells induced by N-nitroso-bis(2-hydroxypropyl)amine.
Topics: Animals; Male; Microscopy, Electron; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms; Rats | 1982 |
Early changes in regenerating hamster pancreas following a single dose of N-nitrosobis (2-oxopropyl)amine (NBOP) administered at the peak of DNA synthesis.
Topics: Animals; Carcinogens; Cell Nucleolus; Cricetinae; Cytoplasmic Granules; DNA; Enzyme Precursors; Interphase; Male; Mesocricetus; Mitosis; Neoplasms, Experimental; Nitrosamines; Pancreas; Pancreatic Neoplasms; Regeneration | 1981 |
An ultrastructural study of precancerous and cancerous lesions of the pancreas in Syrian golden hamsters induced by N-nitrosobis(2-oxopropyl)amine.
Topics: Adenocarcinoma; Animals; Carcinogens; Cricetinae; Mesocricetus; Microscopy, Electron; Nitrosamines; Pancreas; Pancreatic Neoplasms; Precancerous Conditions | 1980 |
Ultrastructural analysis of pancreatic carcinogenesis. IV. Pseudoductular transformation of acini in the hamster pancreas during N-nitroso-bis(2-hydroxypropyl)amine carcinogenesis.
Topics: Animals; Cricetinae; Male; Mesocricetus; Microscopy, Electron; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms | 1981 |
Carcinogenicity of N-nitrosomethyl(2-oxopropyl)amine in Syrian hamsters.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Cell Line; Cricetinae; Digestive System Neoplasms; Female; Injections, Subcutaneous; Lethal Dose 50; Male; Mesocricetus; Mutagens; Neoplasms, Experimental; Neoplasms, Multiple Primary; Nitrosamines; Pancreatic Neoplasms; Respiratory Tract Neoplasms | 1980 |
The role of pancreatic islets in experimental pancreatic carcinogenicity.
Topics: Animals; Carcinogens; Choristoma; Cricetinae; Female; Islets of Langerhans; Islets of Langerhans Transplantation; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Submandibular Gland Diseases | 1995 |
Chemopreventive activity of Oltipraz against N-nitrosobis(2-oxopropyl)amine (BOP)-induced ductal pancreatic carcinoma development and effects on survival of Syrian golden hamsters.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Carcinoma, Ductal, Breast; Cricetinae; Female; Glutathione Transferase; Immunohistochemistry; Liver; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Pyrazines; Thiones; Thiophenes; Tumor Suppressor Protein p53 | 1995 |
Lack of influence of diethylstilbestrol on induced pancreatic ductal carcinomas in Syrian hamsters.
Topics: Adenocarcinoma; Animals; Carcinogens; Cricetinae; Diethylstilbestrol; Female; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Sex Factors | 1995 |
Effects of dietary fish oil (MaxEPA) on N-nitrosobis(2-oxopropyl)amine (BOP)-induced pancreatic carcinogenesis in hamsters.
Topics: Animals; Arachidonic Acid; Carcinogens; Cell Division; Cricetinae; Dinoprostone; Fish Oils; Linoleic Acid; Linoleic Acids; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms | 1995 |
Effects of high fat diet and cholecystokinin receptor blockade on pancreatic growth and tumor initiation in the hamster.
Topics: Animals; Benzodiazepinones; Carcinogens; Cholecystokinin; Cricetinae; Devazepide; Diet; Dietary Fats; DNA; Male; Mesocricetus; Nitrosamines; Organ Size; Pancreas; Pancreatic Neoplasms; Proteins; Receptors, Cholecystokinin; RNA | 1993 |
Inhibitory effects of sulfation inhibitors on initiation of pancreatic ductal carcinogenesis by N-nitrosobis(2-oxopropyl)amine in hamsters.
Topics: Animals; Carcinogens; Cricetinae; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Mesocricetus; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Sulfotransferases | 1995 |
Tumor induction in mice administered neonatally with bis(2-oxopropyl)nitrosamine.
Topics: Adenocarcinoma; Adenoma; Animals; Animals, Newborn; Carcinogens; Carcinoma; Female; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, Inbred ICR; Nasal Cavity; Neoplasms, Experimental; Nitrosamines; Nose Neoplasms; Pancreatic Neoplasms | 1994 |
Multiple genetic alterations in hamster pancreatic ductal adenocarcinomas.
Topics: Animals; Base Sequence; Carcinogens; Carcinoma, Ductal, Breast; Cell Transformation, Neoplastic; Cloning, Molecular; Cricetinae; DNA Primers; DNA, Complementary; Exons; Gene Deletion; Genes, p53; Genes, ras; Genes, Retinoblastoma; Humans; Mesocricetus; Mice; Molecular Sequence Data; Mutation; Nitrosamines; Nuclear Proteins; Oncogenes; Pancreatic Neoplasms; Polymerase Chain Reaction; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Sequence Homology, Amino Acid | 1995 |
The concentration of LH-RH receptors in the nuclei of pancreatic cancer cells. Effect of (D-Trp6)LH-RH on tumor-bearing Syrian golden hamsters.
Topics: Animals; Carcinogens; Cell Nucleus; Cricetinae; Female; Immunohistochemistry; Mesocricetus; Microscopy, Immunoelectron; Nitrosamines; Pancreatic Neoplasms; Radioligand Assay; Receptors, LHRH; Triptorelin Pamoate | 1994 |
Effects of cigarette smoke on N-nitrosobis(2-oxopropyl)amine-induced pancreatic and respiratory tumorigenesis in hamsters.
Topics: Animals; Carcinogens; Cocarcinogenesis; Cricetinae; Male; Mesocricetus; Nicotiana; Nitrosamines; Pancreatic Neoplasms; Plants, Toxic; Respiratory Tract Neoplasms; Smoke | 1994 |
Effects of raw soya diet and cholecystokinin receptor blockade on pancreatic growth and tumor initiation in the hamster.
Topics: Animals; Carcinogens; Cholecystokinin; Cocarcinogenesis; Cricetinae; Diet; Glycine max; Male; Mesocricetus; Nitrosamines; Organ Size; Pancreas; Pancreatic Neoplasms; Receptors, Cholecystokinin | 1994 |
Lack of influence of low blood cholesterol levels on pancreatic carcinogenesis after initiation with N-nitrosobis(2-oxopropyl)amine in Syrian golden hamsters.
Topics: Animals; Carcinogens; Cholesterol; Cholestyramine Resin; Cricetinae; Dioxoles; Female; Lignans; Lipid Peroxides; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1994 |
Blocking effects of synthetic trypsin inhibitor (camostat) on pancreatic carcinogenesis in hamsters initiated with N-nitrosobis(2-oxopropyl)amine.
Topics: Adenocarcinoma; Animals; Carcinogens; Cricetinae; Esters; Female; Gabexate; Guanidines; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1994 |
Effects of dietary linoleic acid on pancreatic carcinogenesis in rats and hamsters.
Topics: Animals; Arachidonic Acid; Azaserine; Carcinogens; Cricetinae; Dietary Fats; Fatty Acids; Linoleic Acid; Linoleic Acids; Male; Mesocricetus; Microsomes; Nitrosamines; Pancreas; Pancreatic Neoplasms; Plant Oils; Precancerous Conditions; Rats; Rats, Wistar; Reference Values; Safflower Oil; Species Specificity; Sunflower Oil | 1994 |
K-ras gene mutation in early ductal lesions induced in a rapid production model for pancreatic carcinomas in Syrian hamsters.
Topics: Animals; Base Sequence; Carcinoma; Codon; Cricetinae; DNA Primers; Female; Genes, ras; Hyperplasia; Mesocricetus; Molecular Sequence Data; Mutagens; Mutation; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms | 1993 |
The relationship between the expression of blood group-related antigens and the cell proliferation of pancreatic carcinomas induced by N-nitrosobis(2-oxopropyl)amine in hamsters.
Topics: ABO Blood-Group System; Animals; Antibodies, Monoclonal; Cell Division; Cricetinae; Female; Immunohistochemistry; Mesocricetus; Neoplasm Transplantation; Nitrosamines; Pancreatic Neoplasms | 1993 |
Production of scatter factor-like activity by a nitrosamine-induced pancreatic cancer cell line.
Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma, Intraductal, Noninfiltrating; Cell Adhesion; Cell Aggregation; Cell Division; Cricetinae; Culture Media; Growth Substances; Heparin; Hepatocyte Growth Factor; Humans; Nitrosamines; Pancreatic Neoplasms; Tumor Cells, Cultured | 1993 |
Glucose tolerance and insulin secretion in experimental pancreatic cancer in the Syrian hamster.
Topics: Animals; Blood Glucose; Carcinogens; Carcinoma; Cricetinae; Disease Models, Animal; Female; Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Mesocricetus; Nitrosamines; Pancreatic Neoplasms | 1993 |
The significance of DNA damage, its repair and cell proliferation during carcinogen treatment in the initiation of pancreatic cancer in the hamster model.
Topics: Alkylation; Animals; Carcinogens; Cell Division; Cricetinae; DNA; DNA Damage; DNA Repair; Female; Guanine; Mesocricetus; Nitrosamines; Pancreatic Neoplasms | 1993 |
Effect of streptozotocin diabetes on development of nitrosamine-induced pancreatic carcinoma when diabetes induction occurs after nitrosamine exposure.
Topics: Animals; Blood Glucose; Body Weight; Carcinogens; Cricetinae; Diabetes Mellitus, Experimental; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Cyst; Pancreatic Neoplasms; Reference Values; Streptozocin | 1993 |
[Effect of combined use of CR1505 with UFT for the tumor growth of the subcutaneously transplanted pancreatic cancer in the Syrian golden hamsters].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cholecystokinin; Cricetinae; Mesocricetus; Neoplasm Transplantation; Nitrosamines; Pancreatic Neoplasms; Proglumide; Tegafur; Uracil | 1993 |
Glycan structure of blood group-A antigen in hamster normal tissues and pancreatic cancers.
Topics: ABO Blood-Group System; Animals; Blotting, Western; Carcinogens; Cell Fractionation; Cell Membrane; Cricetinae; Digestive System; Electrophoresis, Polyacrylamide Gel; Immunohistochemistry; Intracellular Membranes; Mesocricetus; Nitrosamines; Organ Specificity; Pancreas; Pancreatic Neoplasms; Polysaccharides | 1993 |
Chemopreventive effects of 3-phenylpropyl isothiocyanate on hamster lung tumorigenesis initiated with N-nitrosobis(2-oxopropyl)amine.
Topics: Animals; Body Weight; Cricetinae; Female; Isothiocyanates; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Mesocricetus; Nitrosamines; Organ Size; Pancreatic Neoplasms | 1996 |
Overexpression of transforming growth factor-alpha and epidermal growth factor receptor, but not epidermal growth factor, in exocrine pancreatic tumours in hamsters.
Topics: Adenocarcinoma; Animals; Blotting, Northern; Body Weight; Carcinogens; Cricetinae; Epidermal Growth Factor; ErbB Receptors; Immunohistochemistry; Mesocricetus; Nitrosamines; Organ Size; Pancreas; Pancreatic Neoplasms; Polymerase Chain Reaction; Transforming Growth Factor alpha | 1996 |
Effects of sandostatin, alone and in combination with surgical castration, on pancreatic carcinogenesis in rats and hamsters.
Topics: Animals; Anticarcinogenic Agents; Azaserine; Body Weight; Carcinogens; Combined Modality Therapy; Cricetinae; Male; Mesocricetus; Microscopy; Nitrosamines; Octreotide; Orchiectomy; Organ Size; Pancreas; Pancreatic Neoplasms; Pituitary Gland; Rats; Rats, Wistar; Testis | 1996 |
Lack of inhibitory effects of beta-carotene, vitamin C, vitamin E and selenium on development of ductular adenocarcinomas in exocrine pancreas of hamsters.
Topics: Adenocarcinoma; Animals; Ascorbic Acid; beta Carotene; Body Weight; Carcinogens; Carcinoma, Ductal, Breast; Carotenoids; Cricetinae; Diet; Male; Mesocricetus; Nitrosamines; Organ Size; Pancreatic Neoplasms; Selenium; Vitamin E | 1996 |
Chemopreventive effects of phenethyl isothiocyanate on lung and pancreatic tumorigenesis in N-nitrosobis(2-oxopropyl)amine-treated hamsters.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Cricetinae; Female; Isothiocyanates; Lung Neoplasms; Mesocricetus; Nitrosamines; Pancreatic Neoplasms | 1996 |
Stimulation of islet cell proliferation enhances pancreatic ductal carcinogenesis in the hamster model.
Topics: Animals; Antibiotics, Antineoplastic; Blood Glucose; Carcinogens; Cell Division; Cellophane; Cricetinae; Disease Models, Animal; Injections, Subcutaneous; Islets of Langerhans; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Ducts; Pancreatic Neoplasms; Streptozocin; Survival Rate | 1996 |
Hematologic malignancies developing in Syrian golden hamsters during induction of pancreatic carcinoma.
Topics: Aging; Animals; Carcinogens; Cricetinae; Diabetes Mellitus, Experimental; Drug Interactions; Hematologic Neoplasms; Humans; Hyperplasia; Leukemia, Hairy Cell; Lymphoid Tissue; Lymphoma; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Streptozocin; Time Factors | 1996 |
Inhibitory effect of sarcophytol A on pancreatic carcinogenesis after initiation by N-nitrosobis(2-oxypropyl)amine in Syrian hamsters.
Topics: Animals; Antineoplastic Agents; Carcinogens; Cricetinae; Diterpenes; Female; Genes, ras; Mesocricetus; Mutation; Nitrosamines; Pancreatic Neoplasms; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proliferating Cell Nuclear Antigen | 1996 |
K-ras and p53 mutations in hamster pancreatic ductal adenocarcinomas and cell lines.
Topics: Animals; Carcinogens; Carcinoma, Ductal, Breast; Cricetinae; Genes, p53; Genes, ras; Mutation; Nitrosamines; Pancreatic Neoplasms; Polymorphism, Single-Stranded Conformational; Tumor Cells, Cultured | 1996 |
Mutagenic activation of N-nitrosobis(2-oxopropyl)amine by pancreatic juice and assessment of its ductal tumorigenicity following intraductal administration in dogs.
Topics: Animals; Biotransformation; Carcinogens; Chemical and Drug Induced Liver Injury; Dogs; Female; Liver Diseases; Male; Mutagenicity Tests; Mutagens; Nitrosamines; Pancreatic Ducts; Pancreatic Juice; Pancreatic Neoplasms | 1996 |
Expression of receptors for gut peptides in pancreata of BOP-treated and control hamsters.
Topics: Adenocarcinoma; Animals; Carcinogens; Cholecystokinin; Cricetinae; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Precancerous Conditions; Receptors, Cholecystokinin; Receptors, G-Protein-Coupled; Receptors, Gastrointestinal Hormone; Receptors, Somatostatin; Receptors, Vasoactive Intestinal Peptide; Secretin; Somatostatin; Vasoactive Intestinal Peptide | 1996 |
Effects of voluntary physical exercise on high-fat diet-promoted pancreatic carcinogenesis in the hamster model.
Topics: Adenocarcinoma; Animals; Blood Glucose; Carcinogens; Corn Oil; Cricetinae; Dietary Fats; Female; Glucose Tolerance Test; Glutathione; Insulin; Insulin-Like Growth Factor I; Lipids; Liver; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Physical Exertion | 1996 |
Chronic endogenous hypercholecystokininemia promotes pancreatic carcinogenesis in the hamster.
Topics: Animals; Carcinogens; Cholecystokinin; Cricetinae; Duodenum; Gastrins; Male; Mesocricetus; Nitrosamines; Organ Size; Pancreas; Pancreatic Ducts; Pancreatic Neoplasms | 1997 |
[The significance of blood group-related antigen A in a pancreatic cell line (PGHAM-1) in hamsters. With special reference to cell proliferation].
Topics: ABO Blood-Group System; Animals; Antibodies, Monoclonal; Bromodeoxyuridine; Cell Division; Cricetinae; Mesocricetus; Neoplasm Transplantation; Nitrosamines; Pancreatic Neoplasms; Tumor Cells, Cultured | 1997 |
Effect of chronic endogenous hypergastrinaemia on pancreatic growth and carcinogenesis in the hamster.
Topics: Animals; Benzodiazepinones; Carcinogens; Cholecystokinin; Cricetinae; Disease Models, Animal; Gastric Fundus; Gastrins; Hypertrophy; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreas; Pancreatic Neoplasms; Phenylurea Compounds; Receptors, Cholecystokinin | 1997 |
Experimental evidence for the origin of ductal-type adenocarcinoma from the islets of Langerhans.
Topics: Adenocarcinoma; Animals; Carcinogens; Cricetinae; Diabetes Mellitus, Experimental; Female; Immunohistochemistry; Islets of Langerhans; Islets of Langerhans Transplantation; Karyotyping; Lung Neoplasms; Male; Microscopy, Electron; Nitrosamines; Pancreas; Pancreatic Ducts; Pancreatic Neoplasms; Streptozocin; Submandibular Gland Neoplasms | 1997 |
d-Limonene inhibits N-nitrosobis(2-oxopropyl)amine induced hamster pancreatic carcinogenesis.
Topics: Animals; Apoptosis; Body Weight; Bromodeoxyuridine; Carcinoma; Cricetinae; Cyclohexenes; DNA Replication; Limonene; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Terpenes | 1997 |
Mutations of K-ras but not p53 genes in biliary duct and pancreatic duct carcinomas induced in hamsters by cholecystoduodenostomy with dissection of the common duct followed by N-nitrosobis(2-oxopropyl)amine.
Topics: Animals; Bile Duct Neoplasms; Bile Ducts, Extrahepatic; Carcinogens; Cricetinae; Female; Genes, p53; Genes, ras; Humans; Mesocricetus; Mutagenesis; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms | 1997 |
Inhibitory effect of green tea extract on the process of pancreatic carcinogenesis induced by N-nitrosobis-(2-oxypropyl)amine (BOP) and on tumor promotion after transplantation of N-nitrosobis-(2-hydroxypropyl)amine (BHP)-induced pancreatic cancer in Syri
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma; Carcinoma in Situ; Cricetinae; Lung Neoplasms; Lymphatic Metastasis; Mesocricetus; Neoplasm Invasiveness; Neoplasm Transplantation; Nitrosamines; Pancreatic Neoplasms; Tea | 1997 |
Effects of high-fat diet and cholecystokinin receptor blockade on promotion of pancreatic ductal cell tumors in the hamster.
Topics: Animals; Benzodiazepinones; Carcinogens; Cholecystokinin; Cricetinae; Devazepide; Dietary Fats; Male; Mesocricetus; Nitrosamines; Organ Size; Pancreas; Pancreatic Ducts; Pancreatic Neoplasms; Receptors, Cholecystokinin | 1997 |
The effect of streptozotocin and a high-fat diet on BOP-induced tumors in the pancreas and in the submandibular gland of hamsters bearing transplants of homologous islets.
Topics: Adenocarcinoma; Animals; Cricetinae; Dietary Fats; Female; Islets of Langerhans Transplantation; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Streptozocin; Submandibular Gland Neoplasms; Time Factors | 1997 |
In vitro pancreatic ductal cell carcinogenesis.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Epidermal Growth Factor; ErbB Receptors; Genes, p53; Genes, ras; Karyotyping; Keratins; Kinetics; Mice; Microscopy, Electron; Molecular Sequence Data; Mutagenesis; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Rats; Sequence Alignment; Transforming Growth Factor alpha | 1997 |
Dietary energy restriction does not inhibit pancreatic carcinogenesis by N-nitrosobis-2-(oxopropyl)amine in the Syrian hamster.
Topics: Animals; Carcinogens; Cricetinae; Energy Intake; Isoenzymes; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Protein Kinase C | 1997 |
Inhibitory effects of beta-carotene, palm carotene, and green tea polyphenols on pancreatic carcinogenesis initiated by N-nitorsobis(2-oxopropyl)amine in Syrian golden hamsters.
Topics: Animals; beta Carotene; Carcinogens; Carotenoids; Cricetinae; Female; Flavonoids; Fruit; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Phenols; Polymers; Polyphenols; Tea | 1998 |
Enhancing effects of quinacrine on development of hepatopancreatic lesions in N-nitrosobis(2-oxopropyl)amine-initiated hamsters.
Topics: Animals; Antineoplastic Agents; Body Weight; Carcinogens; Cricetinae; Drug Synergism; Female; Kidney Neoplasms; Liver; Liver Neoplasms, Experimental; Lung Neoplasms; Mesocricetus; Microscopy, Electron; Nitrosamines; Organ Size; Pancreatic Neoplasms; Quinacrine | 1998 |
Establishment of tumor cell culture (ILA) derived from hamster pancreatic islets treated with BOP.
Topics: Adenoma, Islet Cell; Animals; Cell Transformation, Neoplastic; Chromosome Aberrations; Cricetinae; ErbB Receptors; Genes, ras; Immunohistochemistry; Islets of Langerhans Transplantation; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Tumor Cells, Cultured | 1998 |
The intracellular mechanism of insulin resistance in the hamster pancreatic ductal adenocarcinoma model.
Topics: Adenocarcinoma; Animals; Carcinogens; Cricetinae; Dietary Fats; Disease Models, Animal; Female; Glycogen Synthase; Insulin; Insulin Resistance; Mesocricetus; Muscle, Skeletal; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Phosphorylases; Physical Exertion; Receptor, Insulin | 1998 |
Induction of adenocarcinoma from hamster pancreatic islet cells treated with N-nitrosobis(2-oxopropyl)amine in vitro.
Topics: Adenoma, Islet Cell; Animals; Carcinogens; Cell Division; Cell Line; Cricetinae; Immunohistochemistry; Islets of Langerhans; Karyotyping; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms | 1999 |
Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine.
Topics: Adenocarcinoma; Animals; Blotting, Western; Collagenases; Cricetinae; Enzyme Activation; Enzyme Precursors; Female; Gelatin; Gelatinases; Immunohistochemistry; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Protease Inhibitors; Quinolones; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-2 | 1999 |
Does dietary alpha-linolenic acid promote liver metastases in pancreatic carcinoma initiated by BOP in Syrian hamster?
Topics: alpha-Linolenic Acid; Animals; Carcinogens; Cricetinae; Dietary Fats, Unsaturated; Incidence; Liver Neoplasms; Mesocricetus; Mutagens; Nitrosamines; Pancreatic Neoplasms | 1999 |
In vitro pancreatic carcinogenesis.
Topics: Animals; Cell Division; Chromosome Aberrations; Cricetinae; Disease Models, Animal; Female; Genes, ras; Islets of Langerhans; Nitrosamines; Organ Culture Techniques; Pancreatic Neoplasms | 1999 |
One thousand faces of Langerhans islets.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cricetinae; Humans; Hyperplasia; Islets of Langerhans; Liver; Mesocricetus; Metaplasia; Nitrosamines; Pancreas; Pancreatic Neoplasms; Stem Cells | 1999 |
Failure of phenethyl isothiocyanate to inhibit hamster tumorigenesis induced by N-nitrosobis(2-oxopropyl)amine when given during the post-initiation phase.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Body Weight; Carcinogenicity Tests; Cricetinae; Dietary Supplements; Female; Isothiocyanates; Kidney Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms | 1999 |
Carcinogenicity of heterocyclic amines for the pancreatic duct epithelium in hamsters.
Topics: Animals; Carbolines; Carcinogens; Cricetinae; Epithelial Cells; Imidazoles; Mutagens; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Quinoxalines | 1999 |
Tauroursodeoxycholate and cholestyramine enhance biliary carcinogenesis in hamsters.
Topics: Administration, Oral; Animals; Anion Exchange Resins; Biliary Tract Neoplasms; Carcinogens; Cholagogues and Choleretics; Cholestyramine Resin; Cricetinae; Drug Synergism; Female; Isomerism; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Taurochenodeoxycholic Acid; Time Factors | 2000 |
In vitro induction of giant cell tumors from cultured hamster islets treated with N-Nitrosobis(2-Oxopropyl)amine.
Topics: Animals; Carcinogens; Cricetinae; Culture Techniques; Female; Giant Cell Tumors; Immunohistochemistry; Islets of Langerhans; Male; Mesocricetus; Mice; Mice, Nude; Microscopy, Electron; Nitrosamines; Pancreatic Neoplasms; Time Factors | 2000 |
Inhibition by methionine of pancreatic carcinogenesis in hamsters after initiation with N-nitrosobis(2-oxopropyl) amine.
Topics: Adipose Tissue; Animals; Body Weight; Carcinogens; Cricetinae; Female; Mesocricetus; Methionine; Nitrosamines; Pancreas; Pancreatic Neoplasms | 2000 |
Lack of involvement of metallothionein expression in pancreatic carcinogenesis by N-nitrosobis (2-oxopropyl) amine in Syrian hamsters.
Topics: Animals; Carcinogens; Cell Division; Cricetinae; Epithelial Cells; Female; Immunohistochemistry; Mesocricetus; Metallothionein; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Time Factors | 2000 |
Inhibitory effects of 1'-acetoxychavicol acetate on N-Nitrosobis(2-oxopropyl)-amine-induced initiation of cholangiocarcinogenesis in Syrian hamsters.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Benzyl Alcohols; Bile Duct Neoplasms; Carcinogens; Carcinoma, Hepatocellular; Cholangiocarcinoma; Cricetinae; Drug Screening Assays, Antitumor; Liver Neoplasms; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Terpenes | 2000 |
Overexpression of midkine in pancreatic duct adenocarcinomas induced by N-Nitrosobis(2-oxopropyl)amine in hamsters and their cell lines.
Topics: Animals; Antineoplastic Agents; Blotting, Northern; Carcinoma, Pancreatic Ductal; Carrier Proteins; Cell Division; Cells, Cultured; Cricetinae; Cytokines; Disease Models, Animal; Female; Fenretinide; Gene Expression; Immunohistochemistry; Mesocricetus; Midkine; Nitrosamines; Pancreatic Neoplasms; RNA, Messenger; Tretinoin | 2000 |
Modifying effects of 4-phenylbutyl isothiocyanate on N-nitrosobis(2-oxopropyl)amine-induced tumorigenesis in hamsters.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Carcinoma, Pancreatic Ductal; Cricetinae; Drug Interactions; Female; Isothiocyanates; Kidney Neoplasms; Liver; Liver Neoplasms, Experimental; Lung Neoplasms; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Organ Size; Pancreatic Neoplasms; Structure-Activity Relationship | 2000 |
Early changes in islet hormone secretion in the hamster pancreatic cancer model.
Topics: Adenocarcinoma; Amyloid; Animals; Carcinogens; Cricetinae; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glucose Tolerance Test; Insulin; Insulin Resistance; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Male; Mesocricetus; Nitrosamines; Pancreatic Juice; Pancreatic Neoplasms; Somatostatin | 2001 |
The impact of laparoscopic biopsy of pancreatic lymph nodes with helium and carbon dioxide on port site and liver metastasis in BOP-induced pancreatic cancer in hamster.
Topics: Animals; Biopsy; Carbon Dioxide; Carcinogens; Cricetinae; Helium; Laparoscopy; Liver Neoplasms, Experimental; Lymph Nodes; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms | 2000 |
Influence of octreotide and tamoxifen on tumor growth and liver metastasis in N-nitrosobis(2-oxopropyl)amine-induced pancreatic cancer in Syrian hamsters.
Topics: Animals; Antineoplastic Agents, Hormonal; Carcinogens; Cricetinae; Incidence; Liver Neoplasms; Male; Mesocricetus; Nitrosamines; Octreotide; Pancreatic Neoplasms; Receptors, Estrogen; Receptors, Somatostatin; Tamoxifen | 2000 |
Absence of beta-catenin gene mutations in pancreatic duct lesions induced by N-nitrosobis(2-oxopropyl)amine in hamsters.
Topics: Animals; beta Catenin; Carcinogens; Carcinoma, Pancreatic Ductal; Cell Membrane; Cell Nucleus; Cricetinae; Cytoplasm; Cytoskeletal Proteins; Female; Immunohistochemistry; Mesocricetus; Mutation; Neoplasms, Experimental; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Signal Transduction; Trans-Activators | 2001 |
Influence of octreotide on liver metastasis and hepatic lipid peroxidation in BOP-induced pancreatic cancer in Syrian hamsters.
Topics: Animals; Carcinogens; Cricetinae; Dietary Fats; Glutathione Peroxidase; Lipid Peroxidation; Liver; Liver Neoplasms; Male; Mesocricetus; Nitrosamines; Octreotide; Pancreas; Pancreatic Neoplasms; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2001 |
The impact of laparoscopic biopsy of pancreatic lymph nodes on lipid peroxidation using helium and carbon dioxide in BOP-induced pancreatic cancer in hamsters.
Topics: Animals; Biopsy; Carbon Dioxide; Carcinoma, Pancreatic Ductal; Cricetinae; Glutathione Peroxidase; Helium; Laparoscopy; Laparotomy; Lipid Peroxidation; Liver Neoplasms; Lymph Nodes; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Pneumoperitoneum, Artificial; Superoxide Dismutase | 2001 |
Influence of antioxidative vitamins A, C and E on lipid peroxidation in BOP-induced pancreatic cancer in Syrian hamsters.
Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Carcinoma, Pancreatic Ductal; Cell Division; Cricetinae; Glutathione Peroxidase; Lipid Peroxidation; Mesocricetus; Nitrosamines; Oxidative Stress; Pancreatic Neoplasms; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vitamin A; Vitamins | 2001 |
Chemopreventive effects of Aloe arborescens on N-nitrosobis(2-oxopropyl)amine-induced pancreatic carcinogenesis in hamsters.
Topics: Adenocarcinoma; Aloe; Animals; Carcinogens; Cricetinae; Female; Nitrosamines; Pancreatic Neoplasms; Plant Extracts | 2002 |
Effects of taurolidine and octreotide on port site and liver metastasis after laparoscopy in an animal model of pancreatic cancer.
Topics: Animals; Antineoplastic Agents; Biopsy; Carcinoma, Pancreatic Ductal; Cricetinae; Diet; Laparoscopy; Liver Neoplasms; Male; Mesocricetus; Neoplasm Seeding; Nitrosamines; Octreotide; Pancreatic Neoplasms; Taurine; Thiadiazines | 2002 |
Improvement of pancreatic cancer model by modified treatment with N-nitroso-bis (2-oxopropyl) amine.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinogens; Carcinoma in Situ; Carcinoma, Intraductal, Noninfiltrating; Cricetinae; Disease Models, Animal; Female; Lung Neoplasms; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Time Factors | 1977 |
Development of biliary and hepatic neoplasms in guinea pigs treated with N-nitrosobis(2-oxopropyl)amine.
Topics: Adenoma, Bile Duct; Animals; Bile Duct Neoplasms; Cricetinae; Guinea Pigs; Liver Neoplasms, Experimental; Male; Neoplasms, Experimental; Nitrosamines; Organ Specificity; Pancreatic Neoplasms; Species Specificity | 1978 |
Metabolism of three radiolabeled pancreatic carcinogenic nitrosamines in hamsters and rats.
Topics: Animals; Bile; Biotransformation; Carbon Dioxide; Carcinoma, Intraductal, Noninfiltrating; Cricetinae; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreatic Juice; Pancreatic Neoplasms; Rats; Species Specificity | 1979 |
Carcinogenicity of N-nitrosobis(2-hydroxypropyl)amine and N-nitrosobis(2-oxopropyl)amine in MRC rats.
Topics: Animals; Female; Gastrointestinal Neoplasms; Hemangioendothelioma; Hemangiosarcoma; Lethal Dose 50; Liver Neoplasms; Male; Microscopy; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms; Rats; Respiratory Tract Neoplasms; Thyroid Neoplasms; Urogenital Neoplasms | 1979 |
Ductular origin of pancreatic cancer and its multiplicity in man comparable to experimentally induced tumors. A preliminary study.
Topics: Adenocarcinoma; Aged; Animals; Cricetinae; Humans; Male; Mesocricetus; Middle Aged; Neoplasms, Experimental; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms | 1979 |
The morphologic and biologic patterns of chemically induced pancreatic adenocarcinoma in Syrian golden hamsters after homologous transplantation.
Topics: Adenocarcinoma; Animals; Cricetinae; Mesocricetus; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms; Transplantation, Homologous | 1979 |
Selective induction of pancreatic ductular tumors by single doses of N-nitrosobis(2-oxopropyl)amine in Syrian golden hamsters.
Topics: Adenocarcinoma; Animals; Cricetinae; Dose-Response Relationship, Drug; Female; Lethal Dose 50; Male; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms; Sex Factors | 1978 |
Pancreatic ductulitis in Syrian golden hamsters bearing homologous transplantable pancreatic adenocarcinomas.
Topics: Adenocarcinoma; Animals; Cricetinae; Male; Mesocricetus; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Pancreatitis; Transplantation, Homologous | 1978 |
Sequential alteration of the pancreas during carcinogenesis in Syrian hamsters by N-nitrosobis(2-oxopropyl)amine.
Topics: Adenocarcinoma; Animals; Cricetinae; Female; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Precancerous Conditions; Time Factors | 1977 |
Induction of pancreatic neoplasms by 2,2'-dioxopropyl-N-propylnitrosamine.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma; Cricetinae; Female; Lung Neoplasms; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms | 1975 |
Effects of caffeine, nicotine, ethanol and sodium selenite on pancreatic carcinogenesis in hamsters after initiation with N-nitrosobis(2-oxopropyl)amine.
Topics: Animals; Body Weight; Caffeine; Carcinogens; Cricetinae; Ethanol; Female; Nicotine; Nitrosamines; Pancreas; Pancreatic Neoplasms; Precancerous Conditions; Selenium; Sodium Selenite | 1992 |
Inhibitory effects of crude soybean trypsin inhibitor on pancreatic ductal carcinogenesis in hamsters after initiation with N-nitrosobis(2-oxopropyl)amine.
Topics: Animals; Body Weight; Carcinogens; Carcinoma, Intraductal, Noninfiltrating; Cricetinae; Drug Interactions; Female; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Precancerous Conditions; Trypsin Inhibitor, Kunitz Soybean | 1992 |
[Effects of crude soybean trypsin inhibitor on pancreatic atrophy induced by BOP treatment in hamsters].
Topics: Adenocarcinoma; Animals; Atrophy; Cricetinae; Female; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Trypsin Inhibitors | 1990 |
Purification and analysis of glycoproteins bearing blood group-A determinants from hamster pancreatic ductal adenocarcinomas.
Topics: ABO Blood-Group System; Animals; Antigens, Neoplasm; Carcinogens; Carcinoma, Intraductal, Noninfiltrating; Cricetinae; Electrophoresis, Polyacrylamide Gel; Epitopes; Glycoside Hydrolases; Immunoblotting; Lectins; Membrane Glycoproteins; Nitrosamines; Oligosaccharides; Pancreas; Pancreatic Neoplasms; Plant Lectins; Sodium Dodecyl Sulfate; Tumor Cells, Cultured | 1992 |
Selective necrosis in hamster pancreatic tumours using photodynamic therapy with phthalocyanine photosensitization.
Topics: Animals; Cricetinae; Female; Fluoroscopy; Indoles; Isoindoles; Mesocricetus; Necrosis; Neoplasms, Experimental; Nitrosamines; Pancreas; Pancreatic Neoplasms; Photochemotherapy; Radiation-Sensitizing Agents | 1992 |
Promoting effects of both dietary cholesterol and cholestyramine on pancreatic carcinogenesis initiated by N-nitrosobis(2-oxopropyl)amine in Syrian golden hamsters.
Topics: Adenocarcinoma; Adenoma; Animals; Bile Acids and Salts; Carcinogenicity Tests; Carcinogens; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Cricetinae; DNA; Female; Hyperplasia; Liver; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1992 |
Mechanism of prevention of development of N-nitrosobis(2-oxopropyl)amine induced pancreatic carcinoma by a protein-free diet in hamsters.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinoma; Cricetinae; Dietary Proteins; Mesocricetus; Nitrosamines; Pancreas Transplantation; Pancreatic Neoplasms; Random Allocation; Survival Rate | 1992 |
Modifications of "A cells" in the development of experimentally induced pancreatic ductal adenocarcinoma: an ultrastructural and immunohistochemical study.
Topics: Adenocarcinoma; Animals; Carcinogens; Cricetinae; Female; Islets of Langerhans; Mesocricetus; Microscopy, Electron; Nitrosamines; Pancreatic Neoplasms | 1992 |
K-ras mutation is an early event in pancreatic duct carcinogenesis in the Syrian golden hamster.
Topics: Adenocarcinoma; Animals; Carcinogens; Cricetinae; DNA Mutational Analysis; Gene Expression Regulation, Neoplastic; Genes, ras; Hyperplasia; Mesocricetus; Mutation; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Polymerase Chain Reaction; Precancerous Conditions | 1992 |
Subcellular localization of blood group A substance produced by pancreatic adenocarcinoma induced in hamsters by N-nitrosobis(2-oxopropyl)amine (BOP) and by its cell line (PC-1).
Topics: ABO Blood-Group System; Adenocarcinoma; Animals; Antibodies, Monoclonal; Antigens, Differentiation; Blotting, Western; CD11 Antigens; CD18 Antigens; Cell Membrane; Cricetinae; Duodenum; Electrophoresis, Polyacrylamide Gel; Humans; Immunohistochemistry; Injections, Subcutaneous; Microscopy, Electron; Neoplasm Transplantation; Nitrosamines; Pancreas; Pancreatic Neoplasms; Receptors, Leukocyte-Adhesion; Sodium Dodecyl Sulfate; Subcellular Fractions; Tumor Cells, Cultured | 1991 |
Effect of combination treatment with analogs of luteinizing hormone-releasing hormone (LH-RH) or somatostatin and 5-fluorouracil on pancreatic cancer in hamsters.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Cricetinae; Drug Screening Assays, Antitumor; Female; Fluorouracil; Gonadotropin-Releasing Hormone; Mesocricetus; Nitrosamines; Organ Size; Pancreatic Neoplasms; Pyrrolidonecarboxylic Acid; Somatostatin | 1991 |
Inhibitory effect of bombesin/gastrin-releasing peptide antagonist RC-3095 and high dose of somatostatin analogue RC-160 on nitrosamine-induced pancreatic cancers in hamsters.
Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Antineoplastic Agents; Bombesin; Carcinogens; Cell Membrane; Cricetinae; ErbB Receptors; Female; Gastrins; Mesocricetus; Molecular Sequence Data; Nitrosamines; Organ Size; Pancreatic Neoplasms; Peptide Fragments; Receptors, Bombesin; Receptors, Neurotransmitter; Somatostatin | 1991 |
Ultrastructural study of the initial phases of pancreatic carcinoma induced by BOP in the Syrian golden hamster.
Topics: Animals; Carcinogens; Carcinoma, Intraductal, Noninfiltrating; Cell Division; Cricetinae; Cytoplasmic Granules; Enzyme Precursors; Female; Mesocricetus; Microscopy, Electron; Nitrosamines; Pancreatic Neoplasms; Staining and Labeling | 1991 |
Effects of sandostatin and castration on pancreatic carcinogenesis in rats and hamsters.
Topics: Animals; Azaserine; Carcinogens; Cricetinae; Drug Interactions; Eating; Growth Substances; Guinea Pigs; Hormones; Male; Mesocricetus; Nitrosamines; Octreotide; Orchiectomy; Organ Size; Pancreas; Pancreatic Neoplasms; Rats; Rats, Inbred Strains | 1992 |
Effects of the synthetic trypsin inhibitor camostate on the development of N-nitrosobis(2-oxopropyl)amine-induced pancreatic lesions in hamsters.
Topics: Animals; Carcinogens; Carcinoma; Carcinoma in Situ; Cholecystokinin; Cricetinae; Esters; Gabexate; Guanidines; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Proglumide; Reference Values; Trypsin Inhibitors | 1991 |
Effects of 3-aminobenzamide on the post-initiation phase of N-nitrosobis(2-oxopropyl)amine induced pancreatic carcinogenesis in Syrian hamsters.
Topics: Animals; Benzamides; Body Weight; Carcinogens; Cricetinae; Dose-Response Relationship, Drug; Eating; Male; Mesocricetus; Nitrosamines; Organ Size; Pancreatic Neoplasms; Poly(ADP-ribose) Polymerase Inhibitors; Radiation-Sensitizing Agents | 1991 |
Effects of castration, alone and in combination with aminoglutethimide, on growth of (pre)neoplastic lesions in exocrine pancreas of rats and hamsters.
Topics: Aminoglutethimide; Animals; Azaserine; Body Weight; Buserelin; Carcinogens; Cricetinae; Epidermal Growth Factor; Gastrins; Goserelin; Male; Mesocricetus; Nitrosamines; Orchiectomy; Organ Size; Pancreatic Neoplasms; Precancerous Conditions; Rats; Rats, Inbred Strains; Somatomedins; Testosterone | 1991 |
Effects of bombesin on the development of N-nitrosobis(2-oxopropyl)amine-induced pancreatic lesions in hamsters.
Topics: Animals; Body Weight; Bombesin; Cholecystokinin; Cricetinae; Liver; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Proglumide | 1991 |
Inhibitory effects of soybean trypsin inhibitor on induction of pancreatic neoplastic lesions in hamsters by N-nitrosobis(2-oxopropyl)amine.
Topics: Adenocarcinoma; Animals; Atrophy; Carcinogens; Cricetinae; Drug Antagonism; Duodenal Neoplasms; Female; Nitrosamines; Pancreatic Neoplasms; Splenic Neoplasms; Stomach Neoplasms; Trypsin Inhibitors | 1991 |
Inhibitory effects of soybean trypsin inhibitor during initiation and promotion phases of N-nitrosobis(2-oxopropyl)amine-induced hamster pancreatic carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Division; Cricetinae; Female; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Rats; Rats, Inbred Strains; Trypsin Inhibitor, Kunitz Soybean | 1991 |
[Experimental study of pancreatic duct adenocarcinoma in dog].
Topics: Adenocarcinoma; Animals; Disease Models, Animal; Dogs; Female; Male; Methylnitronitrosoguanidine; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms | 1991 |
Patterns of growth and metastases of induced pancreatic cancer in relation to the prognosis and its clinical implications.
Topics: Animals; Carcinogens; Cricetinae; Lymph Nodes; Lymphatic Metastasis; Mesocricetus; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Nitrosamines; Pancreatic Neoplasms; Prognosis; Tumor Cells, Cultured | 1991 |
Differences between pancreatropic nitrosamine carcinogens and N-nitrosodimethylamine in methylating DNA in various tissues of hamsters and rats.
Topics: Animals; Cricetinae; Dimethylnitrosamine; DNA Damage; Inactivation, Metabolic; Kidney; Liver; Lung; Mesocricetus; Methylation; Nitrosamines; Pancreas; Pancreatic Neoplasms; Rats | 1991 |
The effect of the somatostatin analogue SMS 201-995 on experimental pancreatic carcinogenesis in the Syrian golden hamster.
Topics: Animals; Cricetinae; Dose-Response Relationship, Drug; Male; Mesocricetus; Nitrosamines; Octreotide; Pancreas; Pancreatic Neoplasms; Species Specificity | 1991 |
Promoting effect of truncal vagotomy on pancreatic carcinogenesis initiated with N-nitrosobis(2-oxopropyl)amine in Syrian golden hamsters.
Topics: Animals; Bile Acids and Salts; Body Weight; Carcinogens; Cholecystokinin; Cricetinae; Female; Gallbladder; Liver; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Vagotomy, Truncal | 1991 |
Effects of catechol and its analogs on pancreatic carcinogenesis initiated by N-nitrosobis(2-oxopropyl)amine in Syrian hamsters.
Topics: Animals; Body Weight; Carcinogens; Catechols; Cricetinae; Female; Gallbladder; Hydroquinones; Liver; Mesocricetus; Nitrosamines; Organ Size; Pancreas; Pancreatic Neoplasms; Resorcinols; Stomach | 1991 |
Hepatic lesions in Syrian golden hamsters with pancreatic carcinoma induced by N-nitrosobis(2-oxopropyl)amine (BOP).
Topics: Animals; Carcinogens; Cricetinae; Female; Liver; Male; Mesocricetus; Nitrosamines; Organ Size; Pancreatic Neoplasms | 1990 |
Inhibition of streptozotocin-induced islet cell tumors and N-nitrosobis(2-oxopropyl)amine-induced pancreatic exocrine tumors in Syrian hamsters by exogenous insulin.
Topics: Adenoma, Islet Cell; Animals; Blood Glucose; Common Bile Duct Neoplasms; Cricetinae; Diabetes Mellitus, Experimental; Gallbladder Neoplasms; Insulin; Insulinoma; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Streptozocin | 1990 |
Regression of nitrosamine-induced pancreatic cancers in hamsters treated with luteinizing hormone-releasing hormone antagonists or agonists.
Topics: Animals; Antineoplastic Agents; Cricetinae; Female; Gonadotropin-Releasing Hormone; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Receptors, Cell Surface; Receptors, LH; Receptors, Somatomedin; Remission Induction; Triptorelin Pamoate | 1990 |
Activation of K-ras in transplantable pancreatic ductal adenocarcinomas of Syrian golden hamsters.
Topics: Animals; Carcinoma, Intraductal, Noninfiltrating; Cricetinae; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, ras; Mesocricetus; Nitrosamines; Pancreatic Neoplasms | 1990 |
Inhibition of pancreatic hepatocyte induction in hamsters treated sequentially with ethionine, a protein-free diet and then methionine by prior N-nitrosobis-(2-oxopropyl)amine administration.
Topics: Adenocarcinoma; Adenoma, Bile Duct; Animals; Carcinogens; Cricetinae; Dose-Response Relationship, Drug; Ethionine; Female; Injections, Subcutaneous; Liver; Mesocricetus; Methionine; Nitrosamines; Pancreas; Pancreatic Neoplasms; Protein-Energy Malnutrition | 1990 |
Pancreatic ductal adenocarcinomas induced in Syrian hamsters by N-nitrosobis(2-oxopropyl)amine contain a c-Ki-ras oncogene with a point-mutated codon 12.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carcinoma, Intraductal, Noninfiltrating; Cricetinae; Exons; Mesocricetus; Molecular Sequence Data; Mutation; Nitrosamines; Oncogenes; Pancreatic Neoplasms; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogene Proteins p21(ras) | 1990 |
Role of cholecystokinin in the development of BOP-induced pancreatic lesions in hamsters.
Topics: Animals; Body Weight; Carcinogens; Cholecystokinin; Cocarcinogenesis; Cricetinae; Male; Nitrosamines; Organ Size; Pancreas; Pancreatic Neoplasms; Proglumide | 1990 |
Effects of various prostaglandin synthesis inhibitors on pancreatic carcinogenesis in hamsters after initiation with N-nitrosobis(2-oxopropyl)amine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinogens; Cricetinae; Female; Indomethacin; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Pancreatitis; Phenylbutazone | 1990 |
Expression of human tumor-associated antigens in pancreatic cancer induced in Syrian hamsters.
Topics: Animals; Antigens, Neoplasm; Antigens, Tumor-Associated, Carbohydrate; Carcinogens; Cricetinae; Glycoproteins; Humans; Immunohistochemistry; Mesocricetus; Neoplasm Transplantation; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1990 |
Usefulness of rapid production model for pancreatic carcinoma in male hamsters.
Topics: Animals; Carcinoma; Choline Deficiency; Cricetinae; Disease Models, Animal; Ethionine; Gallbladder; Male; Methionine; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1990 |
Comparison of the effects of dietary beef tallow and corn oil on pancreatic carcinogenesis in the hamster model.
Topics: Adenocarcinoma; Adenoma; Animals; Body Composition; Body Weight; Carcinogens; Carcinoma in Situ; Corn Oil; Cricetinae; Dietary Fats; Energy Intake; Lipid Metabolism; Lipomatosis; Male; Meat; Meat Products; Mesocricetus; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Plant Oils; Proteins | 1990 |
Inhibitory effect of selenium on hamster pancreatic cancer induction by N'-nitrosobis(2-oxopropyl)amine.
Topics: Animals; Carcinogens; Cricetinae; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Female; Glutathione Peroxidase; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Selenium; Time Factors | 1990 |
Cytokeratin antigen in BOP-induced pancreatic tumors--implications for histogenesis.
Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Cricetinae; Immunohistochemistry; Keratins; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms | 1987 |
Elevated activity of pancreatic type amylase in the urine as an early indicator of pancreatic tumors in hamsters.
Topics: Adenocarcinoma; Amylases; Animals; Clinical Enzyme Tests; Cricetinae; Female; Isoenzymes; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1989 |
Modulation of putative preneoplastic foci in exocrine pancreas of rats and hamsters. Interaction of dietary fat and coffee.
Topics: Animals; Azaserine; Body Weight; Carcinogens; Coffee; Cricetinae; Dietary Fats; Drug Interactions; Male; Nitrosamines; Organ Size; Pancreas; Pancreatic Neoplasms; Precancerous Conditions; Rats; Rats, Inbred Strains; Specific Pathogen-Free Organisms; Time Factors; Weaning | 1989 |
Importance of diabetes in inhibition of pancreatic cancer by streptozotocin.
Topics: Animals; Blood Glucose; Carcinogens; Cricetinae; Diabetes Mellitus, Experimental; Mesocricetus; Nitrosamines; Pancreas Transplantation; Pancreatic Neoplasms; Premedication; Streptozocin | 1989 |
Cycles of repeated augmentation pressure in rapid production of pancreatic and cholangiocellular carcinomas in hamsters initiated with N-nitrosobis(2-oxopropyl)amine.
Topics: Adenoma, Bile Duct; Animals; Body Weight; Carcinogens; Cricetinae; Ethionine; Female; Liver Neoplasms, Experimental; Mesocricetus; Methionine; Nitrosamines; Pancreatic Neoplasms | 1989 |
Treatment of N-nitrosobis(2-oxopropyl)amine-induced pancreatic cancer in Syrian golden hamsters with D-Trp-6-LH-RH and somatostatin analogue RC-160 microcapsules.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capsules; Cricetinae; Female; Gonadotropin-Releasing Hormone; Mesocricetus; Neoplasm Metastasis; Nitrosamines; Organ Size; Pancreatic Neoplasms; Somatostatin; Triptorelin Pamoate | 1989 |
Responsiveness of the hamster pancreatic cancer to treatment with microcapsules of D-Trp-6-LH-RH and somatostatin analog RC-160. Histological evidence of improvement.
Topics: Animals; Antineoplastic Agents; Capsules; Cricetinae; Epithelium; Gonadotropin-Releasing Hormone; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Somatostatin; Triptorelin Pamoate | 1989 |
Presence of membrane binding sites for [D-TRP6]-luteinizing hormone-releasing hormone in experimental pancreatic cancer.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cricetinae; ErbB Receptors; Female; Gonadotropin-Releasing Hormone; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Receptors, LHRH; Receptors, Neurotransmitter; Receptors, Somatostatin; Somatostatin; Triptorelin Pamoate | 1989 |
Alteration of pancreatic endocrine cell patterns and their secretion during pancreatic carcinogenesis in the hamster model.
Topics: Animals; Carcinogens; Cricetinae; Glucagon; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Juice; Pancreatic Neoplasms; Reference Values; Secretin; Sincalide; Somatostatin | 1989 |
Membrane receptors for peptides in experimental and human pancreatic cancers.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Autopsy; Carcinogens; Cricetinae; ErbB Receptors; Female; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Receptors, LHRH; Receptors, Somatotropin; Somatostatin; Triptorelin Pamoate | 1989 |
Determination of thiols and disulfides in normal rat tissues and hamster pancreas treated with N-nitrosobis(2-oxopropyl)amine using 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole and ammonium 7-fluoro-2,1,3-benzoxadiazole-4-sulfonate.
Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cricetinae; Disulfides; Female; Fluorobenzenes; Indicators and Reagents; Mesocricetus; Nitrosamines; Oxadiazoles; Pancreas; Pancreatic Neoplasms; Rats; Rats, Inbred F344; Rats, Inbred Strains; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Tissue Distribution | 1989 |
Experimental pancreatic cancer in the Syrian hamster: effect of cholecystectomy.
Topics: Animals; Carcinogens; Cholecystectomy; Cricetinae; Disease Models, Animal; Female; Incidence; Mesocricetus; Nitrosamines; Organ Size; Pancreatic Neoplasms | 1989 |
Modulation of dietary fat-promoted pancreatic carcinogenesis in rats and hamsters by chronic coffee ingestion.
Topics: Adenocarcinoma; Animals; Azaserine; Cocarcinogenesis; Coffee; Cricetinae; Dietary Fats; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Rats; Rats, Inbred Strains | 1989 |
DNA alkylation in the hamster induced by two pancreatic carcinogens.
Topics: Alkylation; Animals; Carcinogens; Cricetinae; Cytosol; DNA; Kidney; Kinetics; Liver; Lung; Male; Mesocricetus; Microsomes; Mitochondria; Nitrosamines; Pancreas; Pancreatic Neoplasms; Tissue Distribution | 1989 |
Effect of secretin on pancreatic carcinogenesis in the hamster model.
Topics: Adenocarcinoma; Adenoma; Animals; Common Bile Duct Neoplasms; Cricetinae; Disease Models, Animal; Female; Gallbladder Neoplasms; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Secretin | 1989 |
Inhibitory effect of butylated hydroxyanisole administration on pancreatic carcinogenesis in Syrian hamsters initiated with N-nitrosobis(2-oxopropyl)amine.
Topics: Animals; Butylated Hydroxyanisole; Carcinogens; Cricetinae; Female; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Reference Values | 1989 |
Enhancement of pancreatic carcinogenesis in hamsters fed a high-fat diet ad libitum and at a controlled calorie intake.
Topics: Adenocarcinoma; Adenoma; Aging; Animals; Carcinogens; Cricetinae; Diet, Reducing; Dietary Fats; Energy Intake; Gallbladder; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1989 |
Enhancement of BOP-induced pancreatic carcinogenesis in selenium-fed Syrian golden hamsters under specific dietary conditions.
Topics: Animals; Carcinoma, Intraductal, Noninfiltrating; Cricetinae; Dietary Fats; DNA Repair; Food, Formulated; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Papilloma; Selenium; Sex Factors | 1988 |
Effect of cholecystokinin on pancreatic carcinogenesis in the hamster model.
Topics: Adenoma; Animals; Carcinogens; Carcinoma, Intraductal, Noninfiltrating; Cholecystokinin; Cricetinae; Female; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1988 |
Immunohistochemically demonstrated increase in glutathione S-transferase species in propylnitrosamine-induced focal proliferative and neoplastic Syrian hamster pancreatic lesions.
Topics: Animals; Cricetinae; Gene Expression Regulation; Glutathione Transferase; Hyperplasia; Immunoenzyme Techniques; Isoenzymes; Mesocricetus; Neoplasm Proteins; Nitrosamines; Pancreas; Pancreatic Neoplasms; Precancerous Conditions | 1987 |
Modulation of dietary fat-promoted pancreatic carcinogenesis in rats and hamsters by chronic ethanol ingestion.
Topics: Animals; Body Weight; Cricetinae; Dietary Fats; Drinking; Eating; Ethanol; Male; Mesocricetus; Nitrosamines; Organ Size; Pancreatic Neoplasms; Precancerous Conditions; Rats; Rats, Inbred Strains | 1989 |
Cellular toxicity of pancreatic carcinogens.
Topics: Animals; Azaserine; Carcinogens; Cricetinae; Glutamine; Leucine; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Protein Biosynthesis; Rats; Rats, Inbred Strains; Streptozocin; Tritium | 1986 |
Modulation of putative preneoplastic foci in exocrine pancreas of rats and hamsters. I. Interaction of dietary fat and ethanol.
Topics: Adenosine Triphosphatases; Animals; Azaserine; Body Weight; Cricetinae; Dietary Fats; Eating; Ethanol; Male; Mesocricetus; Nitrosamines; Organ Size; Pancreas; Pancreatic Neoplasms; Precancerous Conditions; Rats; Rats, Inbred Strains | 1986 |
Influence of diabetes on susceptibility to experimental pancreatic cancer.
Topics: Animals; Blood Glucose; Cricetinae; Diabetes Mellitus, Experimental; Disease Susceptibility; Male; Mesocricetus; Niacinamide; Nitrosamines; Pancreatic Neoplasms; Streptozocin | 1988 |
Hematoporphyrin derivative uptake and photodynamic therapy in pancreatic carcinoma.
Topics: Adenocarcinoma; Animals; Cricetinae; Drug Evaluation, Preclinical; Hematoporphyrin Derivative; Hematoporphyrin Photoradiation; Hematoporphyrins; Iodine Radioisotopes; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Photochemotherapy; Radiation-Sensitizing Agents; Time Factors; Tissue Distribution | 1988 |
Induction of unusual pancreatic neoplasms, with morphologic similarity to human tumors, and evidence for their ductal/ductular cell origin.
Topics: ABO Blood-Group System; Adenocarcinoma; Animals; Carcinogens; Carcinoma; Carcinoma, Small Cell; Cricetinae; Mesocricetus; Nitrosamines; Pancreatic Neoplasms | 1985 |
Pancreatic cancer in the Syrian hamster induced by N-nitrosobis(2-oxopropyl)-amine: cocarcinogenic effect of epidermal growth factor.
Topics: Adenocarcinoma; Animals; Body Weight; Bronchial Neoplasms; Carcinogens; Cocarcinogenesis; Cricetinae; Epidermal Growth Factor; ErbB Receptors; Female; Mesocricetus; Nitrosamines; Oncogenes; Pancreatic Neoplasms; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor | 1986 |
Induction of exocrine pancreatic, bile duct, and thyroid gland tumors in offspring of Syrian hamsters treated with N-nitrosobis(2-oxopropyl)amine during pregnancy.
Topics: Adenocarcinoma; Adenoma; Animals; Bile Duct Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cricetinae; Female; Male; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms; Pregnancy; Thyroid Neoplasms | 1986 |
Inhibitory effect of dibutyltin dichloride on pancreatic adenocarcinoma development by N-nitrosobis(2-oxopropyl)amine in the Syrian hamster.
Topics: Adenocarcinoma; Animals; Bile Ducts; Carcinogens; Cricetinae; Female; Mesocricetus; Nitrosamines; Organotin Compounds; Pancreatic Neoplasms; Pancreatitis | 1986 |
Rapid production of pancreatic carcinoma by initiation with N-nitroso-bis(2-oxopropyl)amine and repeated augmentation pressure in hamsters.
Topics: Animals; Carcinogens; Carcinoma; Choline Deficiency; Cocarcinogenesis; Cricetinae; Diet; Ethionine; Female; Liver; Mesocricetus; Methionine; Nitrosamines; Pancreatic Neoplasms | 1988 |
Mechanism of pseudoductular (tubular) formation during pancreatic carcinogenesis in the hamster model. An electron-microscopic and immunohistochemical study.
Topics: Animals; Cricetinae; Cytoplasm; Immunohistochemistry; Isoantigens; Mesocricetus; Microscopy, Electron; Nitrosamines; Pancreatic Neoplasms | 1988 |
Augmentation of chemically induced pancreatic and bronchial cancers by epidermal growth factor.
Topics: Animals; Bronchial Neoplasms; Carcinogens; Cocarcinogenesis; Cricetinae; Epidermal Growth Factor; Female; Mesocricetus; Nitrosamines; Pancreatic Neoplasms | 1987 |
Effects of dietary selenium on bis(2-oxopropyl)nitrosamine-induced carcinogenesis in Syrian golden hamsters.
Topics: Animals; Biliary Tract Neoplasms; Body Weight; Carcinogens; Cricetinae; Diet; Female; Glutathione Peroxidase; Liver; Male; Mesocricetus; Necrosis; Nitrosamines; Pancreatic Neoplasms; Selenium; Sex Factors | 1986 |
Pancreatic carcinogenesis: effect of secretin in the hamster- nitrosamine model.
Topics: Adenocarcinoma; Animals; Bicarbonates; Cricetinae; Drug Synergism; Infusions, Intravenous; Injections, Subcutaneous; Male; Mesocricetus; Nitrosamines; Nucleic Acids; Pancreas; Pancreatic Juice; Pancreatic Neoplasms; Secretin; Secretory Rate | 1987 |
Evolution of the expression of fetal acinar antigens during carcinogenesis of the pancreas in hamsters: individual follow-up by open biopsy.
Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; Biopsy; Cricetinae; Cystadenoma; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1987 |
Vascular changes associated with growth of primary and transplantable pancreatic adenocarcinomas induced in Syrian golden hamsters by N-nitrosobis(2-oxopropyl)amine (BOP) and N-nitrosobis(2-hydroxypropyl)amine (BHP).
Topics: Adenocarcinoma; Angiography; Animals; Blood Vessels; Cricetinae; Injections, Subcutaneous; Male; Mathematics; Mesocricetus; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms | 1986 |
Detection of pancreas pretumoral stage by means of organ transplantation.
Topics: Animals; Cricetinae; Mesocricetus; Nitrosamines; Pancreas Transplantation; Pancreatic Neoplasms; Precancerous Conditions; Time Factors | 1986 |
Fibrin deposition in autochthonous Syrian hamster pancreatic adenocarcinomas induced by the chemical carcinogen N-nitroso-bis(2-oxopropyl)amine.
Topics: Adenocarcinoma; Animals; Basement Membrane; Capillary Permeability; Collagen; Cricetinae; Female; Fibrin; Fibrinogen; Fluorescent Antibody Technique; Histocytochemistry; Immunoenzyme Techniques; Laminin; Mesocricetus; Nitrosamines; Pancreatic Neoplasms | 1987 |
Effects of retinoids in N-nitrosobis(2-oxopropyl)amine-treated hamsters.
Topics: Adenocarcinoma; Animals; Atrophy; Carcinogens; Carcinoma in Situ; Cricetinae; Disease Models, Animal; Female; Hyperplasia; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Retinoids; Sex Factors; Testis | 1986 |
Enhanced pancreatic and skin tumorigenesis in cabbage-fed hamsters and mice.
Topics: Animals; Body Weight; Brassica; Cricetinae; Dietary Fats; Female; Gallbladder Neoplasms; Male; Mesocricetus; Mice; Nitrosamines; Pancreatic Neoplasms; Selenium; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triiodothyronine; Vitamin A | 1987 |
Characterization of a 4-month protocol for the quantitation of BOP-induced lesions in hamster pancreas and its application in studying the effect of dietary fat.
Topics: Adenocarcinoma; Animals; Carcinogens; Cricetinae; Dietary Fats; Hyperplasia; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1987 |
Ultrastructural changes in acinar cells of hamster pancreas in chemically induced carcinogenesis.
Topics: Animals; Carcinogens; Cricetinae; Mesocricetus; Microscopy, Electron; Nitrosamines; Pancreas; Pancreatic Neoplasms; Precancerous Conditions; Time Factors | 1987 |
Beta-oxidized N-nitrosoalkylcarbamates as models for DNA alkylation by N-nitrosobis(2-oxopropyl)amine in Syrian hamsters.
Topics: Adenocarcinoma; Alkylation; Animals; Carbamates; Cattle; Cricetinae; DNA; Half-Life; Liver; Mesocricetus; Methylation; Nitrosamines; Pancreatic Neoplasms; Structure-Activity Relationship | 1987 |
Pancreatic lesions induced by a single dose of N-nitrosobis(2-oxopropyl)amine and selection by resistance to cytotoxicity.
Topics: Animals; Cell Survival; Cricetinae; Drug Resistance; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Ducts; Pancreatic Neoplasms | 1986 |
Scanning electron microscopic study of precancerous and cancerous pancreatic lesions induced by N-nitrosobis (2-oxopropyl) amine in Syrian golden hamsters.
Topics: Animals; Carcinogens; Cricetinae; Female; Hyperplasia; Mesocricetus; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Precancerous Conditions | 1986 |
Pancreatic carcinogenicity of N-nitrosobis(2-oxopropyl)-amine in diabetic and non-diabetic Chinese hamsters.
Topics: Animals; Blood Glucose; Body Weight; Carcinogens; Cricetinae; Cricetulus; Diabetes Mellitus, Experimental; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Nitrosamines; Pancreatic Neoplasms; Skin Neoplasms; Species Specificity | 1987 |
Pancreatic carcinogenesis-enhancement by cholecystokinin in the hamster-nitrosamine model.
Topics: Adenocarcinoma; Animals; Cholecystokinin; Cocarcinogenesis; Cricetinae; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Juice; Pancreatic Neoplasms; Precancerous Conditions | 1985 |
Carcinogenic effect of N-nitrosobis (2-oxopropyl)amine in newborn rats.
Topics: Animals; Animals, Newborn; Carcinogens; Female; Kidney Neoplasms; Liver Neoplasms, Experimental; Male; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms; Rats; Rats, Inbred F344; Testicular Neoplasms | 1985 |
The effects of soy flour and N-nitrosobis (2-oxopropyl) amine on the pancreas of the hamster.
Topics: Animals; Body Weight; Cricetinae; Flour; Glycine max; Hot Temperature; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1985 |
Lectin binding affinities of induced pancreatic lesions in the hamster model.
Topics: Animals; Carcinogens; Cricetinae; Cytosol; Female; Hyperplasia; Lectins; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Receptors, Mitogen; Structure-Activity Relationship | 1985 |
Comparative studies on the effects of semipurified and commercial diet on longevity and spontaneous and induced lesions in the Syrian golden hamster.
Topics: Adenoma; Animal Feed; Animals; Body Weight; Cricetinae; Female; Food, Formulated; Kidney; Liver; Longevity; Male; Mesocricetus; Nitrosamines; Organ Size; Pancreas; Pancreatic Neoplasms | 1985 |