nitrosobenzylmethylamine has been researched along with Esophageal Neoplasms in 178 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (24.16) | 18.7374 |
| 1990's | 68 (38.20) | 18.2507 |
| 2000's | 40 (22.47) | 29.6817 |
| 2010's | 22 (12.36) | 24.3611 |
| 2020's | 5 (2.81) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Q; Liu, R; Lu, Q; Pu, Y; Wang, S; Yin, L; Yu, X; Zhang, H; Zhang, Y; Zhao, C; Zhou, J | 1 |
| Liu, R; Lu, L; Pu, Y; Shi, W; Wang, S; Yin, L; Zhang, H; Zhang, Y; Zhao, C; Zhou, Q | 1 |
| Chen, X; Dong, CD; Jiang, Y; Liu, K; Liu, Z; Ren, Y; Wu, Q; Xie, Y; Yao, K; Yuan, Q; Zhang, J; Zhao, J; Zhao, S | 1 |
| Chen, T; Cui, L; Li, L; Li, Z; Qiao, T; Sun, C; Wu, K; Xu, F | 1 |
| Deng, G; Fan, H; Jiang, W; Lu, SH; Yu, X; Zheng, W; Zou, Z | 1 |
| Chen, F; Chen, T; Clinton, SK; Shi, N; Sun, Z; Tang, X; Zhang, X | 1 |
| Deng, X; Fan, H; Guo, L; Jiang, W; Lu, SH; Yu, X; Zhan, Q; Zheng, W; Zou, Z | 1 |
| Fang, J; Jia, X; Li, N; Li, Y; Yang, H | 1 |
| Aleksandrov, VA; Bespalov, VG | 1 |
| Carmella, SG; Chen, JH; Hecht, SS; Huang, YW; Kuo, CT; Oshima, K; Peiffer, DS; Ransom, BW; Siddiqui, J; Stoner, GD; Wang, LS; Zimmerman, NP | 1 |
| Hou, Y; Jiang, D; Li, X | 1 |
| Chen, T; Clinton, SK; Jin, F; Pan, Z; Shi, N; Zhang, X | 1 |
| Chen, Q; Kang, Q; Li, C; Li, Z; Tian, S; Xia, Y; Yan, S; Zhang, S | 1 |
| Jia, X; Li, Y; Liang, C; Sun, N; Yang, H | 1 |
| Cheng, Y; Jiang, Y; Wang, Y; Wei, W; Ye, L; Yu, X | 1 |
| Dombkowski, A; Gu, F; Huang, YW; Stoner, GD; Wang, LS | 1 |
| Chai, CY; Chen, WC; Chen, YK; Cheng, YJ; Ko, HJ; Lin, HS; Liu, YP; Wu, CC; Wu, DC; Wu, IC; Wu, MT | 1 |
| Szumiło, J | 1 |
| Chiu, S; Kinghorn, AD; Rocha, C; Seguin, C; Stoner, GD; Stoner, K; Wang, LS | 1 |
| Henry, C; Larue, B; Lechner, JF; McIntyre, CM; Riedl, KM; Rocha, CM; Schwartz, SJ; Stoner, GD; Wang, LS | 1 |
| Chen, X; Fang, J; Han, C; Jia, X; Li, N; Yang, CS; Yang, H | 1 |
| Abdelrahim, M; Abudayyeh, A; Baker, CH; Basha, R; Herrera, LJ; Kaja, S; Maliakal, C; Maliakal, P; Safe, S; Sankpal, UT | 1 |
| Cukovic, D; Dombkowski, AA; Henry, C; Mukundan, A; Rocha, C; Seguin, C; Stoner, GD; Wang, LS | 1 |
| Basha, R; Ledford, A; Maliakal, C; Maliakal, P; Sankpal, UT; Wanwimolruk, S | 1 |
| Chen, H; Croce, CM; Farber, JL; Fong, LY; Huang, K; Jiang, Y; Liu, XP; Smalley, KJ; Taccioli, C | 1 |
| Chen, X; Jia, X; Li, N; Yang, CS; Yang, H | 1 |
| Feith, DJ; Fong, LY; Pegg, AE | 1 |
| Fukushima, S; Koide, A; Mori, Y; Morimura, K; Tatematsu, K | 1 |
| Ando, A; Asamoto, M; Naito, A; Ochiya, T; Ohnishi, T; Ota, T; Toriyama-Baba, H; Tsuda, H | 1 |
| Carlton, PS; Gopalakrishnan, R; Gupta, A; Habib, S; Liston, BW; Morse, MA; Stoner, GD | 1 |
| Ding, Y; Hashimoto, Y; Hong, T; Imamura, M; Kaganoi, J; Kawabe, A; Komoto, I; Li, ZG; Shimada, Y | 1 |
| Lin, K; Lu, S; Shen, W; Shen, Z; Wu, Y | 1 |
| Imamura, M; Itami, A; Kaganoi, J; Kawabe, A; Komoto, I; Li, ZG; Maeda, M; Sato, F; Shimada, Y | 1 |
| Croce, CM; Farber, JL; Fong, LY; Huebner, K; Ishii, H; Nguyen, VT; Vecchione, A | 1 |
| Aziz, R; Carlton, PS; Frankel, W; Gupta, A; Liston, BW; Nines, R; Stoner, GD | 1 |
| Chen, T; Kresty, LA; Nines, RG; Peschke, SM; Stoner, GD | 1 |
| Chen, T; Stoner, GD | 1 |
| Hara, A; Hata, K; Hirose, Y; Iwasaki, T; Kato, K; Kitaori, N; Kobayashi, H; Kuno, T; Mori, H; Qiang, SH; Wada, K; Yoshimura, T | 1 |
| Fujiwara, Y; Fukushima, S; Hirohashi, K; Lee, S; Morimura, K; Osugi, H; Suehiro, S; Takemura, M | 1 |
| de Boer, JG; Holcroft, J; Skov, K; Yang, H | 1 |
| Aziz, RM; Carlton, PS; Chen, T; Dixit, R; Qin, H; Rose, ME; Stoner, GD | 1 |
| Chen, T; Hwang, H; Nines, RG; Rose, ME; Stoner, GD | 2 |
| Fukumura, A; George, J; Ishizawa, K; Takase, S; Tsutsumi, M | 1 |
| Aziz, RM; Chen, T; Kresty, LA; Nines, R; Reinemann, T; Stoner, GD | 1 |
| Baden, T; Hioki, K; Michiura, T; Tsubura, A; Yamamichi, K | 1 |
| Croce, CM; Druck, T; Huebner, K; Inageta, T; Inoue, H; Ishii, H; Ishikawa, K; Mimori, K; Mori, M; Semba, S; Tani, K; Trapasso, F; Vecchione, A | 1 |
| Aqeilan, HA; Aqeilan, RI; Croce, CM; Fong, LY; Hagan, JP; Pichiorri, F | 1 |
| Cukovic, D; Dombkowski, AA; Kresty, LA; Mele, JM; Nines, R; Reen, RK; Salagrama, S; Stoner, GD | 1 |
| Barch, DH; Hollenberg, PF; Iannaccone, PM; Kuemmerle, SC | 1 |
| Chan, WC; Fong, LY; Lee, JS; Newberne, PM | 2 |
| Jiao, BZ | 1 |
| Lijinsky, W; Reuber, MD; Saavedra, JE; Singer, SS | 1 |
| Gabrial, GN; Newberne, PM; Schrager, TF | 1 |
| Anderson, LM; Armstrong, D; Good, RA; Hsia, CC; Sun, TT; Wang, YY | 1 |
| Hodgson, RM; Kleihues, P; Schweinsberg, F; Wiessler, M | 1 |
| Habs, M; Schmähl, D | 1 |
| Bürkle, V; Schweinsberg, F | 2 |
| Conney, AH; Ho, CT; Huang, MT; Lee, MJ; Wang, LD; Wang, ZY; Yang, CS | 1 |
| Amin, SG; Desai, DH; Francis, DJ; Heffner, EM; Kresty, LA; Morse, MA; Siglin, JC; Stoner, GD; Toburen, AL | 1 |
| Cui, X; Li, H; Lu, S | 2 |
| Guo, YJ; Liang, YY; Lu, SX | 1 |
| Aguelon, AM; Hollams, E; Lozano, JC; Mironov, NM; Yamasaki, H | 1 |
| Kresty, LA; Morse, MA; Stoner, GD; Wilkinson, JT | 1 |
| Barch, DH; Siglin, JC; Stoner, GD | 1 |
| Khare, L; Siglin, JC; Stoner, GD | 1 |
| Alfano, R; Glasgold, M; Glasgold, R; Pinto, J; Savage, H; Schantz, S | 1 |
| Gallant, D | 1 |
| Guo, YJ | 2 |
| Cabral, R; Cros, MP; Lozano, JC; Nakazawa, H; Yamasaki, H | 1 |
| Galati, AJ; Morse, MA; Schmidt, CJ; Stoner, GD; Zu, H | 1 |
| Imada, O; Wargovich, MJ | 1 |
| Earnest, DL; Eskelson, CD; Mufti, SI; Odeleye, OE; Watson, RR | 1 |
| Bijur, GN; Robertson, FM; Sabourin, CL; Stoner, GD; Wang, QS | 1 |
| Calvert, RJ; Stoner, GD; Wang, D; Weghorst, CM | 1 |
| Sabourin, CL; Stoner, GD; Wang, H; Wang, QS | 1 |
| Farber, JL; Fong, LY; Li, JX; Magee, PN | 1 |
| Morse, MA; Stoner, GD | 2 |
| Fukushima, S; Hasuma, T; Higashino, M; Morishima, Y; Osugi, H; Otani, S; Takada, N; Youssef, EM | 1 |
| Fernstrom, MJ; Garber, SA; Ruch, RJ; Stoner, GD | 1 |
| Fong, LY; Huebner, K; Lau, KM; Magee, PN | 1 |
| Castegnaro, M; Galendo, D; Garren, L; Miller, JD; Ohgaki, H; Wild, CP | 1 |
| Balentine, DA; Boone, CW; Harbowy, ME; Kelloff, GJ; Kresty, LA; Morse, MA; Steele, VE; Stoner, GD | 1 |
| Broitman, S; Newberne, PM; Schrager, TF | 1 |
| DeYoung, BR; Khare, L; Sabourin, CL; Stoner, GD; Wagner, BA | 1 |
| Gu, J | 1 |
| Farber, JL; Fong, LY; Magee, PN | 1 |
| Fong, LY; Magee, PN; Pegg, AE | 1 |
| De Young, BR; Jamasbi, RJ; Khare, L; Sabourin, CL; Stoner, GD | 1 |
| Adams, C; Amin, SG; Desai, D; Hecht, SS; Kresty, LA; Morse, MA; Murphy, SE; Stoner, GD | 1 |
| Jenkins, TD; Kent, R; Mueller, A; Odze, R; Rustgi, AK; Shahsafaei, A; Stoner, GD; Zukerberg, LR | 1 |
| Fong, LY; Magee, PN | 1 |
| Carlton, PS; Kresty, LA; Morse, MA; Siglin, JC; Stoner, GD | 1 |
| Ellis, FH; LoCicero, J; Loda, M; Macri, E; Xu, X | 1 |
| Hara, A; Kawabata, K; Koshimizu, K; Mori, H; Murakami, A; Ohigashi, H; Stoner, GD; Tanaka, T; Ushida, J; Yamamoto, T | 1 |
| Lu, SH | 1 |
| Bacus, JV; Bacus, JW; Boone, CW; Kagan, V; Kelloff, GJ; Morse, MA; Stoner, GD | 1 |
| Hara, A; Kawabata, K; Koshimizu, K; Mori, H; Murakami, A; Ohigashi, H; Stoner, GD; Tanaka, T; Yamamoto, T | 1 |
| Fong, L; Li, H; Lu, S | 1 |
| Farber, JL; Fong, LY; Huebner, K; Magee, PN; Nguyen, VT | 1 |
| Fujii, K; Ito, Y; Kawabata, K; Mori, H; Pham, QV; Sugie, S; Takeuchi, H; Tanaka, T; Ushida, J | 1 |
| Carlton, PS; Gupta, A; Hudson, TS; Morse, MA; Stoner, GD | 1 |
| Hodgson, RM; Kleihues, P; Wiessler, M | 1 |
| Bartsch, H; Camus, AM; Ji, C; Lu, SH; Wang, MY; Wang, YL | 1 |
| Carlton, PS; Kresty, LA; Lu, J; Morgan, C; Morse, MA; Siglin, JC; Stoner, GD | 1 |
| Ding, Y; Hong, T; Imamura, M; Kaganoi, J; Kawabe, A; Komoto, I; Li, Z; Maeda, M; Sato, F; Shimada, Y | 1 |
| Fong, LY; Magee, PN; Nguyen, VT; Pegg, AE | 1 |
| Fukushima, S; Hori, T; Kaneko, M; Morimura, K; Nishikawa, A; Nishikawa, T; Osugi, H; Takada, N; Wanibuchi, H | 1 |
| Aziz, RA; Carlton, PS; Gray, DL; Gupta, A; Morse, MA; Nines, R; Rodrigo, KA; Steele, VE; Stoner, GD | 1 |
| Blackwood, M; Carlton, PS; Gupta, A; Kresty, LA; Lu, J; Morgan, C; Morse, MA; Stoner, GD | 1 |
| Carlton, PS; Gupta, A; Harris, GK; Kresty, LA; Liston, BW; Nines, R; Stoner, GD | 1 |
| Farber, JL; Fong, LY; Nguyen, VT | 1 |
| Fukushima, S; Kaneko, M; Kobayashi, Y; Koide, A; Mori, Y; Morimura, K | 1 |
| Fong, LY; Newberne, PM; Sivak, A | 1 |
| Kouros, M; Manncke, K; Schweinsberg, F | 1 |
| Ichmura, S; Iizuka, T; Kawachi, T | 1 |
| Chen, J; Hall, J; Han, C; Hu, G; Wild, CP | 1 |
| Aleksandrov, VA; Bespalov, VG; Petrov, AS; Troian, DN | 2 |
| Aleksandrov, VA; Bardadze, KI; Beniashvili, DSh; Bespalov, VG; Petrov, AS; Sartaniia, MS | 1 |
| Yang, WX | 1 |
| Eskelson, CD; Mufti, SI; Odeleye, OE; Watson, RR | 4 |
| Zhu, M | 1 |
| Chen, J | 1 |
| Barch, DH; Brasitus, TA; Carney, WP; Iannaccone, PM; Jacoby, RF; Radosevich, JA | 1 |
| Chen, JS; Guo, ZL; Liu, ZQ; Xiao, Y; Zhu, JQ | 1 |
| Han, C; Xu, Y | 4 |
| Craddock, VM; Henderson, AR | 3 |
| Kennedy, AR; Newberne, PM; von Hofe, E | 1 |
| Daniel, EM; Stoner, GD | 1 |
| Daniel, EM; Galati, AJ; Heur, YH; Morrissey, DT; Stoner, GD; Wagner, SA | 1 |
| Imaida, K; Takahashi, M | 1 |
| Mufti, SI | 2 |
| Chi, H; Xu, Y | 1 |
| Li, HC | 1 |
| Mandal, S; Stoner, GD | 1 |
| Hioki, K; Kise, Y; Komada, H; Nakagawa, M; Yamamoto, M; Yamamura, M | 1 |
| Dirsch, OR; Kleihues, P; Koenigsmann, M; Ludeke, BI; Scherer, E | 1 |
| Anderson, MW; Reynolds, SH; Stoner, GD; Wang, Y; You, M | 1 |
| Lu, SX | 3 |
| Becker, G; Mufti, SI; Sipes, IG | 1 |
| Barch, DH; Fox, CC | 2 |
| du Bruyn, DB; Hall, JM; van Rensburg, SJ | 1 |
| Xu, NZ | 1 |
| Eng, VW; Gray, K; Stephens, LC; Wargovich, MJ; Woods, C | 1 |
| Barch, DH; Hedvegi, D; Iannaccone, PM; Walloch, J | 1 |
| Bueche, D; Nauss, KM; Newberne, PM | 1 |
| Cottencin, M; Daliam, A; Nicol, M; Ramée, MP; Savouré, N | 1 |
| Ding, ZW; Lin, PZ; Lu, SX; Zhang, JS | 1 |
| Craddock, VM; Driver, HE | 1 |
| Rossnagel, G; Wiessler, M | 1 |
| Craddock, VM | 1 |
| Craddock, VM; Henderson, AR; Sparrow, S | 1 |
| Busby, WF; Goldman, ME; Newberne, PM; Schrager, TF | 1 |
| Gathercole, PS; Hall, JM; van Rensburg, SJ | 1 |
| Archer, MC; Silinskas, KC; Zucker, PF | 1 |
| Bueche, D; Fu, P; Nauss, KM; Newberne, PM; Soule, N; Yew, K | 1 |
| Bogden, JD; Bruening, KS; Chung, HR; Holding, K; Kemp, FW; Naveh, Y | 1 |
| Bai, JF; Cheng, SJ; Chien, F; Guo, SP; Li, MH; Lou, HZ; Zhu, GF | 1 |
| Kobayashi, K | 1 |
| Coville, PF; Maliakal, PP; Wanwimolruk, S | 1 |
7 review(s) available for nitrosobenzylmethylamine and Esophageal Neoplasms
| Article | Year |
|---|---|
[Update on animal models of esophageal carcinoma].
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Dimethylnitrosamine; Disease Models, Animal; Esophageal Neoplasms; Humans; Neoplasm Transplantation | 2014 |
[Natural compounds in chemoprevention of esophageal squamous cell tumors--experimental studies].
Topics: Allyl Compounds; Animals; Anticarcinogenic Agents; Apoptosis; Carcinoma, Squamous Cell; Chemoprevention; Dimethylnitrosamine; DNA Adducts; Esophageal Neoplasms; Fruit; Isothiocyanates; Plant Oils; Rats; Sulfides; Tea | 2009 |
Esophageal carcinogenesis in the rat: a model for aerodigestive tract cancer.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Dimethylnitrosamine; Disease Models, Animal; Esophageal Neoplasms; Humans; Rats | 1993 |
Isothiocyanates as inhibitors of esophageal cancer.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Dimethylnitrosamine; Drug Screening Assays, Antitumor; Esophageal Neoplasms; Isothiocyanates; Male; Rats; Rats, Inbred F344 | 1996 |
Progress of cancer research in China.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Dimethylnitrosamine; Esophageal Neoplasms; Herpesvirus 4, Human; Humans; Liver Neoplasms; Nasopharyngeal Neoplasms | 1997 |
Alterations of oncogenes and tumor suppressor genes in esophageal cancer in China.
Topics: Animals; Carcinogens; China; Dimethylnitrosamine; Esophageal Neoplasms; Genes, Tumor Suppressor; Humans; Loss of Heterozygosity; Mutation; Oncogenes | 2000 |
Modification of tumor development in the gastrointestinal tract.
Topics: 1,2-Dimethylhydrazine; Animals; Cocarcinogenesis; Diet; Dimethylhydrazines; Dimethylnitrosamine; Esophageal Neoplasms; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; Nitroso Compounds | 1991 |
171 other study(ies) available for nitrosobenzylmethylamine and Esophageal Neoplasms
| Article | Year |
|---|---|
Metabolomic transition trajectory and potential mechanisms of N-nitrosomethylbenzylamine induced esophageal squamous cell carcinoma in rats.
Topics: Animals; Carcinogens; Carcinogens, Environmental; Cell Transformation, Neoplastic; Dimethylnitrosamine; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Metabolome; NAD; Niacin; Niacinamide; Nitrogen; Nitrosamines; Rats; Sphingolipids; Tryptophan; Tumor Microenvironment | 2022 |
Multi-omics analysis revealed NMBA induced esophageal carcinoma tumorigenesis via regulating PPARα signaling pathway.
Topics: Animals; Carcinogenesis; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Esophageal Neoplasms; Humans; Multiomics; Nitrosamines; PPAR alpha; Rats; Rats, Inbred F344; Signal Transduction | 2023 |
Ornithine decarboxylase inhibition downregulates multiple pathways involved in the formation of precancerous lesions of esophageal squamous cell cancer.
Topics: Carcinogens; Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Dimethylnitrosamine; Down-Regulation; Esophageal Neoplasms; Humans; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Precancerous Conditions; Signal Transduction | 2020 |
Anticancer effects and possible mechanisms of lycopene intervention on N-methylbenzylnitrosamine induced esophageal cancer in F344 rats based on PPARγ
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Apoptosis; Cell Transformation, Neoplastic; Cyclooxygenase 2; Dimethylnitrosamine; Disease Models, Animal; Esophageal Neoplasms; Esophagus; Inflammation Mediators; Lycopene; Male; NF-kappa B; Oxidative Stress; PPAR gamma; Rats, Inbred F344; Signal Transduction | 2020 |
Aspirin enhances the therapeutic efficacy of cisplatin in oesophageal squamous cell carcinoma by inhibition of putative cancer stem cells.
Topics: Animals; Aspirin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Dimethylnitrosamine; Drug Synergism; Epigenesis, Genetic; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Neoplastic Stem Cells; Rats; Xenograft Model Antitumor Assays | 2021 |
Suppression of Oxidative Stress and NFκB/MAPK Signaling by Lyophilized Black Raspberries for Esophageal Cancer Prevention in Rats.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Dimethylnitrosamine; Esophageal Neoplasms; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Hydrogen Peroxide; Lipid Peroxides; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Oxidative Stress; Rats; Rubus; Superoxide Dismutase | 2017 |
Metformin suppresses the esophageal carcinogenesis in rats treated with NMBzA through inhibiting AMPK/mTOR signaling pathway.
Topics: AMP-Activated Protein Kinases; Animals; Carcinogenesis; Carcinogens; Cell Proliferation; Dimethylnitrosamine; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Hypoglycemic Agents; Male; Metformin; Rats; Rats, Inbred F344; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2019 |
[Effect of vitamin E and selenium deficiency on esophageal tumorigenesis and its oxidative stress mechanism].
Topics: Animals; Dimethylnitrosamine; Esophageal Neoplasms; Male; Oxidative Stress; Rats; Rats, Inbred F344; Selenium; Vitamin E; Vitamin E Deficiency | 2013 |
[Anticarcinogenic effect of potassium salts of glucaric and glucuronic acid in induced models of cervical and esophageal tumors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Calcium Compounds; Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; Disease Models, Animal; Esophageal Neoplasms; Female; Glucaric Acid; Glucuronic Acid; Mice; Potassium Compounds; Salts; Uterine Cervical Neoplasms | 2012 |
Chemoprevention of esophageal cancer with black raspberries, their component anthocyanins, and a major anthocyanin metabolite, protocatechuic acid.
Topics: Animals; Anthocyanins; Anticarcinogenic Agents; Chemoprevention; Diet Therapy; Dimethylnitrosamine; Esophageal Neoplasms; Fruit; Hydroxybenzoates; Male; Plant Extracts; Precancerous Conditions; Rats; Rats, Inbred F344; Rubus | 2014 |
Overexpression of human β-defensin 2 promotes growth and invasion during esophageal carcinogenesis.
Topics: Animals; beta-Defensins; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Dimethylnitrosamine; Esophageal Neoplasms; Gene Knockdown Techniques; Humans; Immunohistochemistry; Rats; Rats, Inbred F344; RNA, Messenger; Transfection | 2014 |
Rhizoma Paridis Saponins Suppresses Tumor Growth in a Rat Model of N-Nitrosomethylbenzylamine-Induced Esophageal Cancer by Inhibiting Cyclooxygenases-2 Pathway.
Topics: Animals; Cell Cycle Checkpoints; Cell Movement; Cell Survival; Cyclin D1; Cyclooxygenase 2; Dimethylnitrosamine; Dinoprostone; Esophageal Neoplasms; Esophagus; G2 Phase Cell Cycle Checkpoints; Male; Plant Extracts; Rats; Rats, Inbred F344; Rhizome; Saponins | 2015 |
[Regulation of α-tocopherol on NFκB and Nrf2 signaling pathway at early stage of N-nitrosomethylbenzylamine⁃induced human esophageal cell carcinogenesis].
Topics: alpha-Tocopherol; Carcinogenesis; Cyclooxygenase 2; Dimethylnitrosamine; Esophageal Neoplasms; Heme Oxygenase-1; Humans; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Signal Transduction | 2015 |
Expression of TP53, BCL-2, and VEGFA Genes in Esophagus Carcinoma and its Biological Significance.
Topics: Animals; Apoptosis; Barrett Esophagus; Carcinoma; Cell Proliferation; Dimethylnitrosamine; Esophageal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Male; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-bcl-6; Rats; Rats, Wistar; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A | 2015 |
Black raspberries demethylate Sfrp4, a WNT pathway antagonist, in rat esophageal squamous cell papilloma.
Topics: Animals; Carcinoma, Squamous Cell; Dimethylnitrosamine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Epigenesis, Genetic; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Gene Expression Regulation, Neoplastic; Humans; Male; Plant Extracts; Proto-Oncogene Proteins; Rats; Rubus; Wnt Signaling Pathway | 2016 |
Overexpression of ATPase Na+/+ transporting alpha 1 polypeptide, ATP1A1, correlates with clinical diagnosis and progression of esophageal squamous cell carcinoma.
Topics: Animals; Arecoline; Biomarkers, Tumor; Carcinogenesis; Carcinoma, Squamous Cell; Cell Line, Tumor; Dimethylnitrosamine; Disease Models, Animal; Disease Progression; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Male; Microarray Analysis; Rats; Sodium-Potassium-Exchanging ATPase; Up-Regulation | 2016 |
Multiple berry types prevent N-nitrosomethylbenzylamine-induced esophageal cancer in rats.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Body Weight; Chemoprevention; Dimethylnitrosamine; Eating; Esophageal Neoplasms; Fruit; Humans; Interleukin-5; Interleukin-8; Male; Phytotherapy; Rats; Rats, Sprague-Dawley | 2010 |
Drinking water with red beetroot food color antagonizes esophageal carcinogenesis in N-nitrosomethylbenzylamine-treated rats.
Topics: Animals; Antigens, CD34; Apoptosis; Beta vulgaris; Cell Proliferation; Dimethylnitrosamine; Disease Models, Animal; Esophageal Neoplasms; Food Coloring Agents; Humans; Leukocyte Common Antigens; Male; Plant Extracts; Plant Roots; Random Allocation; Rats; Rats, Sprague-Dawley; Water | 2010 |
Chemopreventive effects of early-stage and late-stage supplementation of vitamin E and selenium on esophageal carcinogenesis in rats maintained on a low vitamin E/selenium diet.
Topics: Animals; Arachidonate 5-Lipoxygenase; Blotting, Western; Carcinogens; Cell Proliferation; Cyclooxygenase 2; Diet; Dietary Supplements; Dimethylnitrosamine; Dinoprostone; Esophageal Neoplasms; Glutathione Peroxidase; Immunoenzyme Techniques; Leukotriene B4; Male; Neovascularization, Pathologic; Papilloma; Rats; Rats, Inbred F344; Selenium; Vitamin E | 2011 |
Chemopreventive effects of tolfenamic acid against esophageal tumorigenesis in rats.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Cell Survival; Dimethylnitrosamine; Disease Models, Animal; Esophageal Neoplasms; Humans; ortho-Aminobenzoates; Proto-Oncogene Proteins c-met; Rats; Rats, Inbred F344; Sp Transcription Factors; Tumor Burden | 2012 |
Mechanistic basis for the chemopreventive effects of black raspberries at a late stage of rat esophageal carcinogenesis.
Topics: Animals; Antigens, CD34; Apoptosis Regulatory Proteins; Blotting, Western; Dimethylnitrosamine; Dinoprostone; Esophageal Neoplasms; Esophagus; Fruit; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Ki-67 Antigen; Leukotriene B4; Male; Oligonucleotide Array Sequence Analysis; Phytotherapy; Plant Preparations; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Rosaceae; Time Factors | 2011 |
Relevance of drug metabolizing enzyme activity modulation by tea polyphenols in the inhibition of esophageal tumorigenesis.
Topics: Animals; Anticarcinogenic Agents; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Esophageal Neoplasms; Female; Polyphenols; Rats; Rats, Wistar; Tea | 2011 |
Dietary zinc deficiency fuels esophageal cancer development by inducing a distinct inflammatory signature.
Topics: Animal Nutritional Physiological Phenomena; Animals; Calgranulin A; Calgranulin B; Carcinoma, Squamous Cell; Chemokines; Cluster Analysis; Cyclooxygenase 2; Diet; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; Gene Expression Profiling; Immunohistochemistry; Inflammation; Male; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Receptors, Chemokine; Reverse Transcriptase Polymerase Chain Reaction; Weaning; Zinc | 2012 |
Time-selective chemoprevention of vitamin E and selenium on esophageal carcinogenesis in rats: the possible role of nuclear factor kappaB signaling pathway.
Topics: Amino Acids; Animals; Biomarkers; Cell Proliferation; Cell Transformation, Neoplastic; Dietary Supplements; Dimethylnitrosamine; Esophageal Neoplasms; Inflammation; Male; NF-kappa B; Nutritional Status; Rats; Rats, Inbred F344; Selenium; Signal Transduction; Time Factors; Vitamin E | 2012 |
Targeted expression of ornithine decarboxylase antizyme prevents upper aerodigestive tract carcinogenesis in p53-deficient mice.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Cell Proliferation; Cell Transformation, Neoplastic; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Gastric Mucosa; Head and Neck Neoplasms; Mice; Mice, Inbred C57BL; Mice, Transgenic; Polyamines; Proteins; Quinolones; Tongue Neoplasms; Tumor Burden; Tumor Suppressor Protein p53 | 2013 |
The enhancing effect of ethanol on the mutagenic activation of N-nitrosomethylbenzylamine by cytochrome P450 2A in the rat oesophagus.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carcinogens; Colon; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; Ethanol; Kidney; Liver; Lung; Male; Mutagens; N-Nitrosopyrrolidine; Rats; Rats, Inbred F344; Steroid Hydroxylases | 2013 |
Transgenic rats carrying human c-Ha-ras proto-oncogene are highly susceptible to N-nitrosomethylbenzylamine induction of esophageal tumorigenesis.
Topics: Animals; Animals, Genetically Modified; Blotting, Northern; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Dimethylnitrosamine; DNA Mutational Analysis; Esophageal Neoplasms; Genes, ras; Genetic Predisposition to Disease; Humans; Male; Mutation; Papilloma; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Mas; Rats; RNA, Messenger; Sequence Analysis, DNA; Time Factors; Transgenes | 2002 |
Piroxicam is an ineffective inhibitor of N-nitrosomethylbenzylamine-induced tumorigenesis in the rat esophagus.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dimethylnitrosamine; Dinoprostone; Esophageal Neoplasms; Esophagus; Isoenzymes; Male; Membrane Proteins; Piroxicam; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; RNA, Messenger | 2002 |
Suppression of N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumorigenesis in F344 rats by resveratrol.
Topics: Animals; Carcinogenicity Tests; Cyclooxygenase 1; Cyclooxygenase 2; Dimethylnitrosamine; Dinoprostone; Disease Models, Animal; Esophageal Neoplasms; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Resveratrol; RNA, Messenger; Stilbenes; Transcription, Genetic | 2002 |
Dietary exposure and urinary excretion of total N-nitroso compounds, nitrosamino acids and volatile nitrosamine in inhabitants of high- and low-risk areas for esophageal cancer in southern China.
Topics: Adult; Carboxylic Acids; China; Diet; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms; Humans; Inositol Phosphates; Male; Middle Aged; N-Nitrosopyrrolidine; Nitrosamines; Nitroso Compounds; Thiazoles; Thiazolidines | 2002 |
Inhibitory effects of epigallocatechin-3-gallate on N-nitrosomethylbenzylamine-induced esophageal tumorigenesis in F344 rats.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cyclin D1; Cyclooxygenase 1; Cyclooxygenase 2; Dimethylnitrosamine; Dinoprostone; Disease Models, Animal; DNA Primers; Enzyme-Linked Immunosorbent Assay; Esophageal Neoplasms; Esophagus; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urokinase-Type Plasminogen Activator | 2002 |
p53 deficiency accelerates induction and progression of esophageal and forestomach tumors in zinc-deficient mice.
Topics: Animals; Carcinogens; Cell Division; Crosses, Genetic; Diet; Dimethylnitrosamine; Disease Progression; Esophageal Neoplasms; Genotype; Keratins; Mice; Mice, Knockout; Polymerase Chain Reaction; Stomach Neoplasms; Tumor Suppressor Protein p53; Zinc | 2003 |
Perillyl alcohol as a chemopreventive agent in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma, Squamous Cell; Cell Membrane; Dimethylnitrosamine; Esophageal Neoplasms; Male; Monoterpenes; Precancerous Conditions; Random Allocation; ras Proteins; Rats; Rats, Inbred F344 | 2003 |
Chemopreventive effects of a selective nitric oxide synthase inhibitor on carcinogen-induced rat esophageal tumorigenesis.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Dimethylnitrosamine; Eating; Enzyme Inhibitors; Esophageal Neoplasms; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Thiourea | 2004 |
Inducible nitric oxide synthase expression in N-nitrosomethylbenzylamine (NMBA)-induced rat esophageal tumorigenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Esophagus; Immunohistochemistry; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Reverse Transcriptase Polymerase Chain Reaction | 2004 |
Preventive effect of fermented brown rice and rice bran on N-nitrosomethylbenzylamine-induced esophageal tumorigenesis in rats.
Topics: Administration, Oral; Animal Feed; Animals; Carcinogens; Cell Proliferation; Diet; Dimethylnitrosamine; Esophageal Neoplasms; Fermentation; Male; Neoplasms, Experimental; Oryza; Plant Extracts; Rats; Rats, Inbred F344 | 2004 |
Suppressive effect of CPT-11 on rat esophageal tumorigenesis induced by N-nitrosomethylbenzylamine.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Squamous Cell; Dimethylnitrosamine; Disease Models, Animal; DNA, Single-Stranded; Esophageal Neoplasms; Immunohistochemistry; Irinotecan; Male; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Tumor Suppressor Protein p53 | 2004 |
Chemoprotection against N-nitrosomethylbenzylamine-induced mutation in the rat esophagus.
Topics: Allyl Compounds; Animals; Anticarcinogenic Agents; Dimethylnitrosamine; Ellagic Acid; Esophageal Neoplasms; Esophagus; Male; Mutation; Rats; Rats, Inbred F344; Sulfides; Tea | 2004 |
The effects of L-748706, a selective cyclooxygenase-2 inhibitor, on N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis.
Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinogens; Carcinoma, Squamous Cell; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dimethylnitrosamine; Dinoprostone; Esophageal Neoplasms; Gene Expression Regulation, Enzymologic; Male; Piroxicam; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; RNA, Messenger; Sulfones | 2005 |
Chemopreventive properties of black raspberries in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis: down-regulation of cyclooxygenase-2, inducible nitric oxide synthase, and c-Jun.
Topics: Animals; Body Weight; Carcinogens; Carcinoma, Squamous Cell; Cyclooxygenase 2; Diet; Dimethylnitrosamine; Dinoprostone; Down-Regulation; Eating; Esophageal Neoplasms; Fruit; JNK Mitogen-Activated Protein Kinases; Male; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Inbred F344; RNA, Messenger | 2006 |
Effect of chronic dietary ethanol in the promotion of N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in rats.
Topics: Alcohol Drinking; Animals; Carcinogens; Carcinoma, Squamous Cell; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; Esophageal Neoplasms; Male; Neoplasms, Experimental; Rats; Rats, Wistar | 2006 |
Black raspberries inhibit N-nitrosomethylbenzylamine (NMBA)-induced angiogenesis in rat esophagus parallel to the suppression of COX-2 and iNOS.
Topics: Animals; Carcinogens; Cyclooxygenase 2; Dimethylnitrosamine; Esophageal Neoplasms; Female; Fruit; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Microcirculation; Neovascularization, Pathologic; Nitric Oxide Synthase Type II; Plant Extracts; Rats; Rats, Inbred F344 | 2006 |
Protection against esophageal cancer in rodents with lyophilized berries: potential mechanisms.
Topics: Animals; Anticarcinogenic Agents; Cyclooxygenase 2; Diet; Dimethylnitrosamine; Dinoprostone; DNA Adducts; Esophageal Neoplasms; Esophagus; Food Preservation; Fragaria; Freeze Drying; Fruit; Gene Expression; Guanosine; Nitric Oxide Synthase Type II; Nitrites; Phytotherapy; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Rosaceae; Weight Gain | 2006 |
Sequential endoscopic findings and histological changes of N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in rats.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Dimethylnitrosamine; Endoscopy; Esophageal Neoplasms; Male; Rats; Rats, Inbred F344 | 2006 |
Fhit modulates the DNA damage checkpoint response.
Topics: Acid Anhydride Hydrolases; Animals; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Checkpoint Kinase 1; Dimethylnitrosamine; DNA Damage; Esophageal Neoplasms; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Humans; Immunoblotting; Immunohistochemistry; Mice; Mice, Knockout; Mice, Transgenic; Microscopy, Fluorescence; Mutation; Neoplasm Proteins; Protein Kinases; Stomach Diseases; Transfection | 2006 |
Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; Disease Progression; Esophageal Neoplasms; Gene Silencing; Genetic Predisposition to Disease; Immunohistochemistry; Mice; Neoplasms, Squamous Cell; Oxidoreductases; Stomach Neoplasms; WW Domain-Containing Oxidoreductase | 2007 |
Effects of phenylethyl isothiocyanate on early molecular events in N-nitrosomethylbenzylamine-induced cytotoxicity in rat esophagus.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome; Isothiocyanates; Oligonucleotide Array Sequence Analysis; Precancerous Conditions; Rats; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Esophageal microsomal metabolism of N-nitrosomethylbenzylamine in the zinc-deficient rat.
Topics: Animals; Carcinogens; Diet; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; Male; Microsomes; Rats; Rats, Inbred Strains; Zinc | 1984 |
Zinc deficiency and the development of esophageal and forestomach tumors in Sprague-Dawley rats fed precursors of N-nitroso-N-benzylmethylamine.
Topics: Animals; Benzylamines; Biotransformation; Dimethylnitrosamine; Esophageal Neoplasms; Male; Nitrites; Rats; Rats, Inbred Strains; Stomach Neoplasms; Zinc | 1984 |
[Studies on canceration of esophageal epithelium--(SEM) and (TEM) observations].
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Esophagus; Mice; Microscopy, Electron; Microscopy, Electron, Scanning; Neoplasms, Experimental; Nitrosamines | 1983 |
Esophageal carcinogenesis in F344 rats by nitrosomethylethylamines substituted in the ethyl group.
Topics: Animals; Dimethylnitrosamine; Esophageal Neoplasms; Liver Neoplasms; Male; Rats; Rats, Inbred F344 | 1982 |
Zinc deficiency, alcohol, and retinoid: association with esophageal cancer in rats.
Topics: Animals; Body Weight; Cocarcinogenesis; Copper; Diet; Dimethylnitrosamine; Esophageal Neoplasms; Ethanol; Isotretinoin; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tretinoin; Zinc | 1982 |
Enhancement of formation of the esophageal carcinogen benzylmethylnitrosamine from its precursors by Candida albicans.
Topics: Benzylamines; Biotransformation; Candida albicans; Chromatography, High Pressure Liquid; Dimethylnitrosamine; Esophageal Neoplasms; Humans; Kinetics; Mass Spectrometry; Sodium Nitrite | 1981 |
Mechanism of esophageal tumor induction in rats by N-nitrosomethylbenzylamine and its ring-methylated analog N-nitrosomethyl(4-methylbenzyl)amine.
Topics: Animals; Carcinogens; Dimethylnitrosamine; DNA; Esophageal Neoplasms; Esophagus; Liver; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1982 |
Zinc deficiency and the induction of oesophageal tumors in rats by benzylmethylamine and sodium nitrite.
Topics: Amines; Animals; Benzylamines; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Male; Neoplasms, Experimental; Nitrites; Rats; Rats, Inbred Strains; Sodium Nitrite; Stomach Neoplasms; Zinc | 1982 |
Experiments on the influence of an aromatic retinoid on the chemical carcinogenesis induced by N-nitroso-methyl benzylamine in rats.
Topics: Animals; Carcinogens; Dimethylnitrosamine; Drug Interactions; Esophageal Neoplasms; Etretinate; Female; Male; Neoplasms, Experimental; Rats; Tretinoin | 1981 |
[Effect of disulfiram on the toxicity and carcinogenicity of N-methyl-n-nitrosobenzylamine in rats (author's transl)].
Topics: Animals; Bronchial Neoplasms; Dimethylnitrosamine; Disulfiram; Drug Synergism; Esophageal Neoplasms; Female; Neoplasms, Experimental; Precancerous Conditions; Rats; Tracheal Neoplasms | 1981 |
Inhibition of N-nitrosomethylbenzylamine-induced esophageal tumorigenesis in rats by green and black tea.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Male; Rats; Rats, Sprague-Dawley; Tea | 1995 |
Enhancement of esophageal carcinogenesis in male F344 rats by dietary phenylhexyl isothiocyanate.
Topics: Animals; Carcinogens; Diet; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Synergism; Esophageal Neoplasms; Esophagus; Isothiocyanates; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1995 |
[Correlation studies on the alterations of multiple tumor suppressor genes in human esophageal cancer and in human and monkey esophageal epithelial cells treated with N-methyl-N-benzyl nitrosamine].
Topics: Animals; Carcinogens; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Genes, APC; Genes, MCC; Genes, p53; Genes, Retinoblastoma; Genes, Tumor Suppressor; Humans; Macaca mulatta; Mutation; Polymerase Chain Reaction | 1995 |
[Multiple tumor suppressor genes in esophageal carcinoma induced in human fetus esophageal epithelium by NMBzA].
Topics: Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Fetus; Gene Deletion; Genes, Tumor Suppressor; Humans; Point Mutation | 1995 |
[Alterations of oncogenes in human fetal esophageal epithelium induced by N-methylbenzylnitrosamine (NMBzA)].
Topics: Carcinogens; Carcinoma, Squamous Cell; Culture Techniques; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Esophagus; Fetus; Gene Amplification; Gene Deletion; Genes, erbB-1; Genes, myc; Genes, p53; Genes, Retinoblastoma; Humans; Hyperplasia; Proto-Oncogenes | 1994 |
Microsatellite alterations in human and rat esophageal tumors at selective loci.
Topics: Adult; Aged; Aged, 80 and over; Animals; Carcinogens; Carcinoma, Squamous Cell; Dimethylnitrosamine; DNA, Neoplasm; DNA, Satellite; Electrophoresis; Esophageal Neoplasms; Humans; Male; Mice; Mice, Inbred Strains; Middle Aged; Papilloma; Polymerase Chain Reaction; Rats; Repetitive Sequences, Nucleic Acid | 1995 |
Effect of alkyl chain length on inhibition of N-nitrosomethylbenzylamine-induced esophageal tumorigenesis and DNA methylation by isothiocyanates.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Esophageal Neoplasms; Isothiocyanates; Male; Methylation; Molecular Structure; Rats; Rats, Inbred F344; Structure-Activity Relationship | 1995 |
Effects of dietary phenethyl isothiocyanate, ellagic acid, sulindac and calcium on the induction and progression of N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in rats.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Calcium; Carcinogens; Diet; Dimethylnitrosamine; Ellagic Acid; Esophageal Neoplasms; Isothiocyanates; Male; Rats; Rats, Inbred F344; Sulindac; Time Factors | 1995 |
Evaluation of dose and treatment duration on the esophageal tumorigenicity of N-nitrosomethylbenzylamine in rats.
Topics: Animals; Body Weight; Carcinogens; Cell Division; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Eating; Esophageal Neoplasms; Esophagus; Evaluation Studies as Topic; Injections, Subcutaneous; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344 | 1995 |
Tissue autofluorescence as an intermediate endpoint in NMBA-induced esophageal carcinogenesis.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Dimethylnitrosamine; Esophageal Neoplasms; Fluorescence; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Spectrum Analysis | 1994 |
Vitamin E and ethanol-enhanced carcinogenesis.
Topics: Animals; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Ethanol; Female; Free Radicals; Lipid Peroxidation; Mice; Neoplasms, Experimental; Reactive Oxygen Species; Vitamin E | 1993 |
[Amplification of int-2 gene in primary esophageal carcinoma and fetal esophageal carcinoma induced by N-methyl-N-benzylnitrosamine (NMBzA)].
Topics: Carcinoma, Squamous Cell; Dimethylnitrosamine; Esophageal Neoplasms; Fetus; Gene Amplification; Humans; Proto-Oncogenes | 1993 |
G-->A mutations in p53 and Ha-ras genes in esophageal papillomas induced by N-nitrosomethylbenzylamine in two strains of rats.
Topics: Adenine; Animals; Base Sequence; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Genes, p53; Genes, ras; Guanine; Molecular Sequence Data; Papilloma; Point Mutation; Rats; Rats, Inbred F344 | 1994 |
Dose-related inhibition by dietary phenethyl isothiocyanate of esophageal tumorigenesis and DNA methylation induced by N-nitrosomethylbenzylamine in rats.
Topics: Animals; Anticarcinogenic Agents; Diet; Dimethylnitrosamine; DNA, Neoplasm; Dose-Response Relationship, Drug; Esophageal Neoplasms; Isothiocyanates; Male; Methylation; Rats; Rats, Inbred F344 | 1993 |
Modulation of cancer growth by vitamin E and alcohol.
Topics: Alcohol Drinking; Alcoholism; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Dimethylnitrosamine; Esophageal Neoplasms; Female; Mice; Mice, Inbred C57BL; Vitamin E | 1993 |
Alterations in transforming growth factor-alpha and epidermal growth factor receptor expression during rat esophageal tumorigenesis.
Topics: Animals; Base Sequence; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Dimethylnitrosamine; DNA Primers; ErbB Receptors; Esophageal Neoplasms; Esophagus; Gene Expression; In Situ Hybridization; Male; Molecular Sequence Data; Papilloma; Polymerase Chain Reaction; Precancerous Conditions; Rats; Rats, Inbred F344; RNA, Messenger | 1996 |
Mutation in the p53 tumor suppressor gene in rat esophageal papillomas induced by N-nitrosomethylbenzylamine.
Topics: Animals; Base Sequence; Carcinogens; Dimethylnitrosamine; DNA Primers; Esophageal Neoplasms; Exons; Genes, p53; Introns; Male; Molecular Sequence Data; Mutation; Papilloma; Polymorphism, Single-Stranded Conformational; Rats; Rats, Inbred F344 | 1996 |
Overexpression of cyclin D1 and cyclin E in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis.
Topics: Animals; Base Sequence; Carcinogens; Cyclin D1; Cyclins; Dimethylnitrosamine; DNA Primers; Esophageal Neoplasms; Immunohistochemistry; Male; Molecular Sequence Data; Oncogene Proteins; Papilloma; Polymerase Chain Reaction; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; RNA, Messenger | 1996 |
Cell proliferation and esophageal carcinogenesis in the zinc-deficient rat.
Topics: Aging; Animals; Body Weight; Bromodeoxyuridine; Carcinogens; Cell Division; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; Male; Mitotic Index; Papilloma; Rats; Rats, Sprague-Dawley; Reference Values; S Phase; Time Factors; Weaning; Zinc | 1996 |
Overexpression of cyclin D1 in rat esophageal carcinogenesis model.
Topics: Animals; Cyclin D1; Cyclins; Dimethylnitrosamine; Esophageal Neoplasms; Immunohistochemistry; Male; Oncogene Proteins; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344 | 1997 |
Isothiocyanates and plant polyphenols as inhibitors of lung and esophageal cancer.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Carcinogens; Dimethylnitrosamine; DNA Methylation; Dose-Response Relationship, Drug; Ellagic Acid; Esophageal Neoplasms; Female; Guanine; Isothiocyanates; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Nitrosamines; Rats; Rats, Inbred F344 | 1997 |
Altered gap junctional intercellular communication in neoplastic rat esophageal epithelial cells.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Communication; Cell Line; Connexin 43; Connexins; Dimethylnitrosamine; Epithelial Cells; Epithelium; Esophageal Neoplasms; Esophagus; Gap Junctions; Immunohistochemistry; Precancerous Conditions; Rats; Tumor Cells, Cultured | 1997 |
Induction of esophageal tumors in zinc-deficient rats by single low doses of N-nitrosomethylbenzylamine (NMBA): analysis of cell proliferation, and mutations in H-ras and p53 genes.
Topics: Animals; Cell Division; Cocarcinogenesis; Dimethylnitrosamine; Dose-Response Relationship, Drug; Epithelium; Esophageal Neoplasms; Genes, p53; Genes, ras; Immunohistochemistry; Male; Mutation; Polymorphism, Single-Stranded Conformational; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Zinc | 1997 |
Absence of a synergistic effect between fumonisin B1 and N-nitrosomethylbenzylamine in the induction of oesophageal papillomas in the rat.
Topics: Animals; Carboxylic Acids; Carcinogens; Cocarcinogenesis; Dimethylnitrosamine; Drug Synergism; Esophageal Neoplasms; Fumonisins; Infusions, Parenteral; Male; Papilloma; Rats | 1997 |
Effects of theaflavins on N-nitrosomethylbenzylamine-induced esophageal tumorigenesis.
Topics: Animals; Benzocycloheptenes; Biological Assay; Catechin; Dimethylnitrosamine; Esophageal Neoplasms; Gallic Acid; Male; Molecular Structure; Phenols; Rats; Rats, Inbred F344; Tea | 1997 |
Esophageal carcinogenesis in the rat: zinc deficiency, DNA methylation and alkyltransferase activity.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Chromatography, High Pressure Liquid; Dimethylnitrosamine; Disease Models, Animal; DNA Methylation; DNA, Neoplasm; Esophageal Neoplasms; Esophagus; Male; Necrosis; O(6)-Methylguanine-DNA Methyltransferase; Papilloma; Rats; Rats, Sprague-Dawley; Zinc | 1997 |
Alterations in the expression of alpha6beta4 integrin and p21/WAF1/Cip1 in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis.
Topics: Animals; Antigens, Surface; Biomarkers, Tumor; Blotting, Northern; Carcinogens; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dimethylnitrosamine; Disease Models, Animal; Disease Progression; Esophageal Neoplasms; Esophagus; Fluorescent Antibody Technique; Integrin alpha6beta4; Integrins; Male; Polymerase Chain Reaction; Precancerous Conditions; Rats; Rats, Inbred F344; RNA, Messenger; Transcription, Genetic | 1998 |
Zinc replenishment reduces esophageal cell proliferation and N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumor incidence in zinc-deficient rats.
Topics: Animals; Carcinogens; Cell Division; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; Male; Rats; Rats, Sprague-Dawley; Zinc | 1998 |
Alpha-difluoromethylornithine inhibits N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in zinc-deficient rats: effects on esophageal cell proliferation and apoptosis.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Biogenic Polyamines; Carcinogens; Cell Division; Cocarcinogenesis; Diet; Dimethylnitrosamine; Eflornithine; Esophageal Neoplasms; Esophagus; Male; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Zinc | 1998 |
Altered localization of E-cadherin and alpha-catenin in rat esophageal tumors.
Topics: alpha Catenin; Animals; Blotting, Western; Cadherins; Cytoskeletal Proteins; Dimethylnitrosamine; Esophageal Neoplasms; Immunohistochemistry; Male; Rats; Rats, Inbred F344; Tumor Cells, Cultured | 1999 |
Inhibition of N'-nitrosonornicotine-induced esophageal tumorigenesis by 3-phenylpropyl isothiocyanate.
Topics: Animals; Anticarcinogenic Agents; Biotransformation; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; Isothiocyanates; Male; Nitrosamines; Rats; Rats, Inbred F344 | 1998 |
Cyclin D1 overexpression combined with N-nitrosomethylbenzylamine increases dysplasia and cellular proliferation in murine esophageal squamous epithelium.
Topics: Animals; Carcinogens; Cell Division; Cyclin D1; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Gene Expression; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Squamous Cell | 1999 |
Dietary zinc deficiency enhances esophageal cell proliferation and N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumor incidence in C57BL/6 mouse.
Topics: Animals; Body Weight; Bromodeoxyuridine; Carcinogens; Cell Division; Dimethylnitrosamine; Eating; Epithelial Cells; Esophageal Neoplasms; Esophagus; Male; Mice; Mice, Inbred C57BL; Zinc | 1999 |
Isothiocyanates and freeze-dried strawberries as inhibitors of esophageal cancer.
Topics: Animals; Dimethylnitrosamine; Ellagic Acid; Esophageal Neoplasms; Freeze Drying; Fruit; Guanosine; Humans; Isothiocyanates; Male; Rats; Rats, Inbred F344 | 1999 |
Barrett's esophagus and associated adenocarcinoma in a mouse surgical model.
Topics: Adenocarcinoma; Animals; Barrett Esophagus; Dimethylnitrosamine; Esophageal Neoplasms; Esophagostomy; Jejunostomy; Mice | 2000 |
Suppression of N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis by dietary feeding of 1'-acetoxychavicol acetate.
Topics: Animals; Anticarcinogenic Agents; Benzyl Alcohols; Biogenic Polyamines; Dimethylnitrosamine; DNA Adducts; Esophageal Neoplasms; Male; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Terpenes | 2000 |
Quantitative grading of rat esophageal carcinogenesis using computer-assisted image tile analysis.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Carcinogens; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Image Interpretation, Computer-Assisted; Incidence; Isothiocyanates; Male; Neoplasms, Multiple Primary; Rats; Rats, Inbred F344; Time Factors | 2000 |
Suppression of N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis by dietary feeding of auraptene.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Coumarins; Diet; Dimethylnitrosamine; Esophageal Neoplasms; Incidence; Male; Rats; Rats, Inbred F344 | 2000 |
[Study on the status of methylation of Rb gene promoter in human esophageal cancer and effect of NMBzA on Rb gene promoter in monkey esophageal epithelium].
Topics: Animals; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Esophagus; Gene Expression Regulation; Genes, Retinoblastoma; Humans; Macaca mulatta; Methylation; Promoter Regions, Genetic | 1998 |
Early deregulation of the the p16ink4a-cyclin D1/cyclin-dependent kinase 4-retinoblastoma pathway in cell proliferation-driven esophageal tumorigenesis in zinc-deficient rats.
Topics: Animals; Carcinogens; Carrier Proteins; Cell Division; Cocarcinogenesis; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinases; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; G1 Phase; Immunohistochemistry; Male; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Retinoblastoma Protein; S Phase; Signal Transduction; Zinc | 2000 |
Chemopreventive effect of curcumin on N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in rats.
Topics: Animals; Anticarcinogenic Agents; Bromodeoxyuridine; Carcinogens; Curcumin; Dimethylnitrosamine; Esophageal Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 2000 |
Investigation of the enhancement of N-nitrosomethylbenzylamine-induced esophageal tumorigenesis by 6-phenylhexyl isothiocyanate.
Topics: Animals; Carcinogens; Cyclin D1; Dimethylnitrosamine; Esophageal Neoplasms; Isothiocyanates; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344 | 2001 |
Preferential methylation of target organ DNA by the oesophageal carcinogen N-nitrosomethylbenzylamine.
Topics: Animals; Biotransformation; Carcinogens; Dimethylnitrosamine; DNA Methylation; Esophageal Neoplasms; Esophagus; Male; Organ Specificity; Rats; Rats, Wistar; Tissue Distribution | 1980 |
Mutagenicity in Salmonella typhimurium of N-3-methylbutyl-N-1-methyl-acetonyl-nitrosamine and N-methyl-N-benzylnitrosamine, N-nitrosation products isolated from corn-bread contaminated with commonly occurring moulds in linshien county, a high incidence ar
Topics: Animals; Bread; Carcinogens; China; Dimethylnitrosamine; Esophageal Neoplasms; Female; Mutagenicity Tests; Nitrosamines; Rats; Salmonella typhimurium | 1980 |
Inhibition of N-nitrosomethylbenzylamine-induced tumorigenesis in the rat esophagus by dietary freeze-dried strawberries.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Dimethylnitrosamine; DNA Adducts; Esophageal Neoplasms; Fruit; Male; Rats | 2001 |
Suppression of N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumorigenesis in F344 rats by JTE-522, a selective COX-2 inhibitor.
Topics: Animals; Benzenesulfonates; Body Weight; Carcinogens; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dimethylnitrosamine; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Esophageal Neoplasms; Esophagus; Isoenzymes; Male; Oxazoles; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction | 2001 |
Alpha-difluoromethylornithine induction of apoptosis: a mechanism which reverses pre-established cell proliferation and cancer initiation in esophageal carcinogenesis in zinc-deficient rats.
Topics: Analysis of Variance; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Division; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p16; Diet; Dimethylnitrosamine; Disease Models, Animal; Drug Interactions; Eflornithine; Enzyme Inhibitors; Esophageal Neoplasms; Genes, bcl-2; Immunohistochemistry; Male; Polyamines; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Zinc | 2001 |
Promotion of chemically induced rat esophageal tumorigenesis with post-initiation ethanol modification.
Topics: Animals; Bromodeoxyuridine; Carcinogens; Cyclin D1; Dimethylnitrosamine; Disease Progression; Epithelium; Esophageal Neoplasms; Esophagus; Ethanol; Hyperplasia; Immunohistochemistry; Male; Rats; Rats, Inbred F344 | 2001 |
Effects of dietary N-(4-hydroxyphenyl)retinamide on N-nitrosomethylbenzylamine metabolism and esophageal tumorigenesis in the Fischer 344 rat.
Topics: Alitretinoin; Animals; Antineoplastic Agents; Carcinogens; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; DNA Adducts; Esophageal Neoplasms; Esophagus; Fenretinide; Male; Rats; Rats, Inbred F344; Retinoids; RNA, Messenger; Time Factors; Tretinoin | 2001 |
Chemoprevention of esophageal tumorigenesis by dietary administration of lyophilized black raspberries.
Topics: Animals; Carcinogens; Chemoprevention; Diet; Dimethylnitrosamine; DNA Adducts; Ellagic Acid; Esophageal Neoplasms; Freeze Drying; Fruit; Guanine; Male; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344 | 2001 |
Incidence and effects of Ha-ras codon 12 G-->A transition mutations in preneoplastic lesions induced by N-nitrosomethylbenzylamine in the rat esophagus.
Topics: Animals; Carcinogens; Cell Cycle Proteins; Codon; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Dimethylnitrosamine; Disease Progression; DNA Primers; Esophageal Neoplasms; Genes, ras; Hypoxanthine Phosphoribosyltransferase; Incidence; Male; Papilloma; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Precancerous Conditions; Rats; Rats, Inbred F344; RNA, Messenger; Tumor Suppressor Proteins | 2001 |
Esophageal cancer prevention in zinc-deficient rats: rapid induction of apoptosis by replenishing zinc.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Carbonates; Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; Epithelial Cells; Esophageal Neoplasms; Esophagus; Gene Expression Regulation, Neoplastic; Hyperplasia; Male; Neoplasm Proteins; Papilloma; Precancerous Conditions; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Zinc; Zinc Compounds | 2001 |
Effect of ethanol treatment on metabolic activation and detoxification of esophagus carcinogenic N-nitrosamines in rat liver.
Topics: Animals; Blotting, Western; Carcinogens; Cytochrome P-450 CYP2E1; Densitometry; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms; Ethanol; Glucuronosyltransferase; Immunoblotting; Liver; Male; Mutagens; Mutation; Nitrosamines; Rats; Rats, Inbred F344; Rats, Wistar; Solvents | 2002 |
Zinc deficiency and methylbenzylnitrosamine-induced esophageal cancer in rats.
Topics: Animals; Carcinoma, Squamous Cell; Dimethylnitrosamine; DNA; Esophageal Neoplasms; Esophagus; In Vitro Techniques; Liver; Male; Neoplasms, Experimental; Nitrosamines; Rats; RNA; Time Factors; Zinc | 1978 |
[Comparative investigations on the organotropic carcinogenic effect of different N-nitroso compounds with rat after single and chronic treatment (author's transl)].
Topics: Animals; Benzyl Compounds; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms; Female; Kidney Neoplasms; Liver Neoplasms, Experimental; Neoplasms, Experimental; Organ Specificity; Pharyngeal Neoplasms; Rats; Time Factors | 1979 |
Autoradiography and organ distribution of N-methyl-N-nitro-sobenzylamine in rats.
Topics: Animals; Autoradiography; Benzylamines; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; Liver; Male; Neoplasms, Experimental; Nitrosamines; Rats; Tissue Distribution | 1978 |
Lack of effects of selenium on N-nitrosomethylbenzylamine-induced tumorigenesis, DNA methylation, and oncogene expression in rats and mice.
Topics: Animals; Biological Assay; Carcinogens; Deoxyguanosine; Dimethylnitrosamine; DNA, Neoplasm; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Genes, myc; Male; Methylation; Methyltransferases; Mice; Mice, Inbred Strains; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Wistar; Selenium; Stomach Neoplasms | 1992 |
[The inhibiting effect of epsilon-aminocaproic acid on the incidence of induced tumors of the esophagus, nervous system and kidneys].
Topics: Aminocaproic Acid; Animals; Anticarcinogenic Agents; Carcinogens; Chi-Square Distribution; Dimethylnitrosamine; Drug Screening Assays, Antitumor; Esophageal Neoplasms; Ethylnitrosourea; Female; Incidence; Kidney Neoplasms; Male; Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Rats | 1992 |
[Esophageal tumor induction in monkeys].
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Dimethylnitrosamine; Disease Models, Animal; Esophageal Neoplasms; Esophagoscopy; Esophagus; Female; Macaca fascicularis; Male; Nitrosamines; Papilloma; Time Factors | 1992 |
[The anticarcinogenic effects of fumaric acid on models of carcinogenesis in the esophagus, nervous system and kidney].
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Chi-Square Distribution; Dimethylnitrosamine; Disease Models, Animal; Drug Screening Assays, Antitumor; Esophageal Neoplasms; Ethylnitrosourea; Female; Fumarates; Kidney Neoplasms; Male; Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Rats | 1992 |
[Exposure level of N-nitrosamines in the gastric juice and its inhibition by vitamin C in high risk areas of esophageal cancer].
Topics: Adult; Aged; Ascorbic Acid; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; Female; Gastric Juice; Humans; Hyperplasia; Male; Middle Aged; N-Nitrosopyrrolidine; Nitrosamines; Precancerous Conditions | 1992 |
Vitamin E protection against nitrosamine-induced esophageal tumor incidence in mice immunocompromised by retroviral infection.
Topics: Animals; Carcinogens; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Esophageal Neoplasms; Female; Immunocompromised Host; Lipid Peroxidation; Liver; Liver Diseases; Lymph Nodes; Mice; Mice, Inbred BALB C; Murine Acquired Immunodeficiency Syndrome; Organ Size; Retroviridae Infections; Spleen; Vitamin A; Vitamin E | 1992 |
[Influence of dietary selenium level on immune function of rats with esophageal tumors induced by methylbenzylnitrosamine (NMBzA)].
Topics: Animals; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Hemolytic Plaque Technique; Hypersensitivity, Delayed; Killer Cells, Natural; Male; Rats; Rats, Inbred Strains; Selenium | 1992 |
[Overexpression of p53 protein in human spontaneous esophageal carcinoma and fetal esophageal carcinoma induced by N-methyl-N-benzylnitrosamine (NMBzA)].
Topics: Adenocarcinoma; Carcinogens; Carcinoma, Squamous Cell; Dimethylnitrosamine; Epithelial Cells; Esophageal Neoplasms; Fetus; Genes, p53; Humans; Immunohistochemistry; Tumor Suppressor Protein p53 | 1992 |
Vitamin E inhibition of lipid peroxidation and ethanol-mediated promotion of esophageal tumorigenesis.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Dimethylnitrosamine; Eating; Esophageal Neoplasms; Ethane; Ethanol; Female; Free Radicals; Lipid Peroxidation; Liver; Malondialdehyde; Mice; Mice, Inbred C57BL; Organ Size; Vitamin A; Vitamin E | 1992 |
Vitamin E inhibits the carcinogenicity of N-nitrosomethylbenzylamine.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Ethanol; Female; Liver; Mice; Mice, Inbred C57BL; Vitamin A; Vitamin E | 1992 |
Effects of supplemental vitamin E on cancer growth and promotion during murine AIDS.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Female; Food, Fortified; Lipid Peroxidation; Liver; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Vitamin E | 1992 |
The effects of Chinese tea on the occurrence of esophageal tumors induced by N-nitrosomethylbenzylamine in rats.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Dimethylnitrosamine; DNA; Esophageal Neoplasms; Male; Methylation; Mice; Nitrosation; Rats; Rats, Inbred Strains; Tea | 1992 |
Incidence of Harvey ras oncogene point mutations and their expression in methylbenzylnitrosamine-induced esophageal tumorigenesis.
Topics: Adenine; Animals; Base Sequence; Carcinogens; Codon; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; Gene Expression Regulation, Neoplastic; Genes, ras; Guanine; Immunohistochemistry; Male; Molecular Sequence Data; Mutation; Oncogene Protein p21(ras); Papilloma; Rats; Rats, Inbred Strains | 1991 |
The effects of Chinese tea on the methylation of DNA by the esophageal carcinogen N-nitrosomethylbenzylamine.
Topics: Animals; Anticarcinogenic Agents; Autoradiography; Dimethylnitrosamine; DNA; Esophageal Neoplasms; Guanine; Male; Methylation; Purine Nucleotides; Rats; Rats, Inbred Strains; Tea | 1991 |
[Prevention of in vivo formation of NMBz A and the formation of oesophageal tumour by tea in rats].
Topics: Animals; Benzylamines; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Male; Papilloma; Plant Extracts; Rats; Rats, Inbred Strains; Sodium Nitrite; Tea | 1991 |
Chinese tea inhibits the occurrence of oesophageal tumours induced by N-nitrosomethylbenzylamine and blocks its formation in rats.
Topics: Animals; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Rats; Rats, Inbred Strains; Tea | 1991 |
Potent inhibition of oesophageal metabolism of N-nitrosomethylbenzylamine, an oesophageal carcinogen, by higher alcohols present in alcoholic beverages.
Topics: Alcoholic Beverages; Alcohols; Animals; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; In Vitro Techniques; Microsomes; Rats | 1991 |
Inhibition of N-nitrosomethylbenzylamine-induced esophageal neoplasms by the Bowman-Birk protease inhibitor.
Topics: Animals; Carcinogens; Carcinoma; Dimethylnitrosamine; Disease Models, Animal; Drug Antagonism; Esophageal Neoplasms; Esophagus; Hyperplasia; Male; Papilloma; Rats; Rats, Inbred Strains; Tablets; Trypsin Inhibitor, Bowman-Birk Soybean | 1991 |
The effects of ellagic acid and 13-cis-retinoic acid on N-nitrosobenzylmethylamine-induced esophageal tumorigenesis in rats.
Topics: Animals; Antineoplastic Agents; Body Weight; Carcinogens; Diet; Dimethylnitrosamine; Drug Synergism; Ellagic Acid; Esophageal Neoplasms; Male; Rats; Rats, Inbred F344; Tretinoin | 1991 |
Inhibitory effects of phenethyl isothiocyanate on N-nitrosobenzylmethylamine carcinogenesis in the rat esophagus.
Topics: Animals; Carcinogens; Dimethylnitrosamine; DNA; Drug Screening Assays, Antitumor; Esophageal Neoplasms; Esophagus; Isothiocyanates; Male; Rats; Rats, Inbred F344; Thiocyanates | 1991 |
Free radicals generated in ethanol metabolism may be responsible for tumor promoting effects of ethanol.
Topics: Animals; Carcinogens; Cocarcinogenesis; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms; Ethanol; Free Radicals; Glutathione; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred Strains | 1991 |
The effect of Chinese tea on the occurrence of esophageal tumors induced by N-nitrosomethylbenzylamine formed in vivo.
Topics: Animals; Body Weight; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Humans; Male; Papilloma; Rats; Rats, Inbred Strains; Tea | 1990 |
[Retinoblastoma gene in human esophageal cancer].
Topics: Blotting, Southern; Dimethylnitrosamine; Esophageal Neoplasms; Genes, Neoplasm; Genes, Retinoblastoma; Humans; Precancerous Conditions | 1990 |
Inhibition of N-nitrosobenzylmethylamine-induced esophageal tumorigenesis in rats by ellagic acid.
Topics: Animals; Antineoplastic Agents; Benzopyrans; Dimethylnitrosamine; Ellagic Acid; Esophageal Neoplasms; Esophagus; Male; Rats; Rats, Inbred F344 | 1990 |
An animal model of immune response associated with alcohol-related cancers.
Topics: Alcoholism; Animals; Cocarcinogenesis; Dimethylnitrosamine; Disease Models, Animal; Esophageal Neoplasms; Ethanol; Immunity, Cellular; Immunosuppressive Agents; Male; Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Inbred Strains | 1990 |
Effect of dietary molybdenum on esophageal carcinogenesis in rats induced by N-methyl-N-benzylnitrosamine.
Topics: Animals; Body Weight; Carcinogens; Diet; Dimethylnitrosamine; Dose-Response Relationship, Drug; Esophageal Neoplasms; Esophagus; Male; Molybdenum; Rats; Rats, Inbred F344 | 1990 |
The effect of Chinese tea on occurrence of esophageal tumor induced by N-nitrosomethylbenzylamine in rats.
Topics: Animals; Body Weight; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Female; Male; Rats; Rats, Inbred Strains; Tea | 1990 |
Bioactivation of N-nitrosomethylbenzylamine and N-nitrosomethyl-amylamine in oesophageal papillomas.
Topics: Animals; Autoradiography; Biotransformation; Carbon Radioisotopes; Carcinogens; Deoxyguanosine; Dimethylnitrosamine; Esophageal Neoplasms; Male; Nitrosamines; Papilloma; Rats; Rats, Inbred F344 | 1990 |
Mutational activation of the cellular Harvey ras oncogene in rat esophageal papillomas induced by methylbenzylnitrosamine.
Topics: Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; DNA, Neoplasm; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Genes, ras; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Transfection | 1990 |
[Esophageal carcinoma in human fetus induced by N-methyl-N-benzylnitrosamine (NMBzA)].
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Culture Techniques; Dimethylnitrosamine; DNA, Neoplasm; Epithelium; Esophageal Neoplasms; Fetus; Mice; Mice, Inbred BALB C; Mice, Nude; Repetitive Sequences, Nucleic Acid | 1989 |
[The effect of Chinese teas on the occurrence of oesophageal tumor caused by N-nitrosomethylbenzylamine in rats].
Topics: Animals; Dimethylnitrosamine; Esophageal Neoplasms; Female; Male; Rats; Rats, Inbred Strains; Tea | 1989 |
Effect of chronic dietary ethanol consumption on the initiation and promotion of chemically-induced esophageal carcinogenesis in experimental rats.
Topics: Animals; Carcinogens; Cocarcinogenesis; Dimethylnitrosamine; Esophageal Neoplasms; Ethanol; Male; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Dietary ellagic acid reduces the esophageal microsomal metabolism of methylbenzylnitrosamine.
Topics: Animals; Benzopyrans; Biotransformation; Diet; Dimethylnitrosamine; Ellagic Acid; Esophageal Neoplasms; Esophagus; In Vitro Techniques; Male; Microsomes; Rats; Rats, Inbred Strains | 1989 |
Effects of various dietary staples on esophageal carcinogenesis induced in rats by subcutaneously administered N-nitrosomethylbenzylamine.
Topics: Animals; Bone and Bones; Dietary Fiber; Dimethylnitrosamine; Esophageal Neoplasms; Magnesium; Rats; Rats, Inbred Strains; Risk; Vitamins; Zinc | 1985 |
[Sister chromatid exchange rate in detecting susceptible individuals to esophageal cancer].
Topics: Adolescent; Adult; Aged; Dimethylnitrosamine; Esophageal Neoplasms; Female; Humans; Male; Middle Aged; Sister Chromatid Exchange | 1986 |
Chemoprevention of N-nitrosomethylbenzylamine-induced esophageal cancer in rats by the naturally occurring thioether, diallyl sulfide.
Topics: Allyl Compounds; Animals; Carcinogens; Cell Nucleus; Dimethylnitrosamine; DNA Damage; Esophageal Neoplasms; Male; Microsomes; Rats; Rats, Inbred Strains; Sulfides | 1988 |
[N-nitrosamines in gastric juice of subjects from high incidence area of esophageal cancer].
Topics: Carcinogens; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Esophagus; Gastric Juice; Humans; Hyperplasia; N-Nitrosopyrrolidine; Nitrosamines | 1988 |
Histopathology of methylbenzylnitrosamine-induced esophageal carcinoma in the rat: comparison with cytomorphology.
Topics: Animals; Carcinoma; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Male; Rats; Rats, Inbred Strains; Zinc | 1986 |
Effect of vitamin A nutriture on experimental esophageal carcinogenesis.
Topics: Animals; Body Weight; Diet; Dimethylnitrosamine; Esophageal Neoplasms; Liver; Male; Nutritional Status; Rats; Rats, Inbred Strains; Vitamin A; Vitamin A Deficiency | 1987 |
[Vitamin A status and the carcinogenic action of N-nitrosobenzyl methylamine on the esophagus in the rat].
Topics: Animals; Dimethylnitrosamine; Enzyme Induction; Esophageal Neoplasms; Keratosis; Neoplasms, Experimental; Ornithine Decarboxylase; Rats; Tretinoin; Vitamin A; Vitamin A Deficiency | 1987 |
[Carcinogenic and promoting effects of Roussin red methyl ester (RRME) on the forestomach epithelium of mice and esophageal epithelium of rats, and its inhibition by retinamide and vitamin C].
Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Dimethylnitrosamine; Esophageal Neoplasms; Female; Mice; Nitroso Compounds; Rats; Rats, Inbred Strains; Stomach Neoplasms; Tretinoin | 1986 |
Sequential histological studies of rat oesophagus during the rapid initiation of cancer by repeated injection of N-methyl-N-benzylnitrosamine.
Topics: Animals; Carcinogens; Carcinoma; Dimethylnitrosamine; Esophageal Neoplasms; Female; Papilloma; Precancerous Conditions; Rats; Rats, Inbred Strains; Time Factors | 1987 |
Dietary zinc deficiency increases the methylbenzylnitrosamine-induced formation of O6-methylguanine in the esophageal DNA of the rat.
Topics: Animals; Deficiency Diseases; Dimethylnitrosamine; DNA; Esophageal Neoplasms; Esophagus; Guanine; Male; Mutation; Rats; Rats, Inbred Strains; Zinc | 1987 |
Effect of the esophageal carcinogen methylbenzylnitrosamine and of a putative potentiating factor, a trichothecene mycotoxin, on O6-methylguanine-dna methyl transferase in rat esophagus and liver.
Topics: Animals; Cocarcinogenesis; Dimethylnitrosamine; DNA Ligases; Enzyme Induction; Esophageal Neoplasms; Esophagus; Female; Fusarium; Liver; Mycotoxins; Polynucleotide Ligases; Rats; Rats, Inbred Strains; Sesquiterpenes; Trichothecenes | 1987 |
Alpha-glucuronides of N-nitrosomethylbenzylamine.
Topics: Animals; Dimethylnitrosamine; Esophageal Neoplasms; Glucuronates; Male; Rats; Rats, Inbred Strains | 1987 |
Effect of the trichothecene mycotoxin diacetoxyscirpenol on nitrosamine-induced oesophageal cancer and on relevant enzymes in oesophagus and liver.
Topics: Animals; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; Liver; Nitrosamines; Rats; Sesquiterpenes; Trichothecenes | 1987 |
The effect of the trichothecene mycotoxin diacetoxyscirpenol on nitrosamine-induced esophageal cancer in the rat.
Topics: Animals; Cocarcinogenesis; Dimethylnitrosamine; Esophageal Neoplasms; Female; Mycotoxins; Rats; Rats, Inbred Strains; Sesquiterpenes; Trichothecenes | 1986 |
Enhancement of methylbenzylnitrosamine-induced esophageal carcinogenesis in zinc-deficient rats: effects on incorporation of [3H]thymidine into DNA of esophageal epithelium and liver.
Topics: Animals; Cell Division; Cocarcinogenesis; Diet; Dimethylnitrosamine; DNA; Epithelium; Esophageal Neoplasms; Esophagus; Liver; Male; Mitosis; Rats; Rats, Inbred Strains; Thymidine; Time Factors; Zinc | 1986 |
Effect of N-nitrosamines carcinogenic for oesophagus on O6-alkyl-guanine-DNA-methyl transferase in rat oesophagus and liver.
Topics: Alkylation; Animals; Cysteine; Dimethylnitrosamine; DNA; DNA Repair; DNA Replication; Esophageal Neoplasms; Esophagus; Guanine; Liver; Liver Neoplasms, Experimental; Methyltransferases; Nitrosamines; O(6)-Methylguanine-DNA Methyltransferase; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1986 |
Inhibition of esophageal carcinogenesis in corn-fed rats by riboflavin, nicotinic acid, selenium, molybdenum, zinc, and magnesium.
Topics: Animals; Calcium; Carcinogens; Diet; Dimethylnitrosamine; Esophageal Neoplasms; Magnesium; Molybdenum; Niacin; Papilloma; Rats; Rats, Inbred Strains; Riboflavin; Selenium; Zea mays; Zinc | 1986 |
Mechanism of organ specificity in nitrosamine carcinogenesis.
Topics: Animals; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Liver; Liver Neoplasms, Experimental; Neoplasms, Experimental; Phenobarbital; Rats | 1986 |
Effect of dietary selenium levels on methylbenzylnitrosamine-induced esophageal cancer in rats.
Topics: Animals; Dimethylnitrosamine; Esophageal Neoplasms; Glutathione Peroxidase; Glutathione Transferase; Liver; Male; Rats; Selenium; Sulfhydryl Compounds | 1986 |
Effect of selenium and molybdenum on methylbenzylnitrosamine-induced esophageal lesions and tissue trace metals in the rat.
Topics: Analysis of Variance; Animals; Dimethylnitrosamine; Drug Interactions; Esophageal Neoplasms; Iron; Male; Manganese; Metals; Molybdenum; Precancerous Conditions; Rats; Rats, Inbred Strains; Selenium; Tissue Distribution | 1986 |
[Mutagenic effect of methylbenzylnitrosamine on V79 cells co-cultivated with hepatocytes or esophageal epithelial cells of human, rat and chicken origins].
Topics: Animals; Biotransformation; Carcinogens; Cells, Cultured; Chickens; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Esophagus; Humans; Liver; Male; Mutation; Rats; Rats, Inbred Strains; Sister Chromatid Exchange; Species Specificity | 1985 |
[Effect of sex hormone on the experimental induction of esophageal cancer].
Topics: Animals; Benzylamines; Carcinoma, Squamous Cell; Castration; Cocarcinogenesis; Dimethylnitrosamine; Esophageal Neoplasms; Estradiol; Female; Male; Neoplasms, Multiple Primary; Rats; Rats, Inbred Strains; Testosterone | 1985 |
Nitrite: a co-carcinogen?
Topics: Animals; Cocarcinogenesis; Dimethylnitrosamine; Drug Synergism; Esophageal Neoplasms; Female; Neoplasms, Experimental; Nitrites; Rats; Respiratory System; Sodium Nitrite | 1985 |
[Promoting effect of Roussin red methyl ester (RRME) in the pickled vegetables in Linxian County on the forestomach epithelium of mice].
Topics: Animals; Carcinogens; China; Dimethylnitrosamine; Drug Synergism; Esophageal Neoplasms; Male; Mice; Mutagens; Nitroso Compounds; Papilloma; Stomach Neoplasms; Vegetables | 1985 |
Decreased hepatic drug metabolising enzyme activity in rats with nitrosamine-induced tumours.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Carcinoma, Squamous Cell; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Activation; Esophageal Neoplasms; Female; Liver; Microsomes, Liver; Nitrosamines; Organ Specificity; Oxidoreductases, N-Demethylating; Rats; Rats, Wistar | 2002 |