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nitroglycerin and Transposition of Great Vessels

nitroglycerin has been researched along with Transposition of Great Vessels in 6 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Transposition of Great Vessels: A congenital cardiovascular malformation in which the AORTA arises entirely from the RIGHT VENTRICLE, and the PULMONARY ARTERY arises from the LEFT VENTRICLE. Consequently, the pulmonary and the systemic circulations are parallel and not sequential, so that the venous return from the peripheral circulation is re-circulated by the right ventricle via aorta to the systemic circulation without being oxygenated in the lungs. This is a potentially lethal form of heart disease in newborns and infants.

Research Excerpts

ExcerptRelevanceReference
"With the dosage regimen used, supplemented with epinephrine, amrinone provides a higher cardiac output and more favorable oxygen dynamics than a combination of dopamine and nitroglycerin."2.69Amrinone versus dopamine and nitroglycerin in neonates after arterial switch operation for transposition of the great arteries. ( Happonen, JM; Laitinen, P; Peltola, K; Rautiainen, P; Sairanen, H, 1999)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oskarsson, G1
Pesonen, E1
Munkhammar, P1
Sandström, S1
Jögi, P1
Takada, K1
Fujita, M1
Satoh, M1
Sohma, N1
Shiina, K1
Nomura, M1
Nishiyama, K1
Shirai, K1
Kurosawa, H1
Imai, Y1
Iwanami, H1
Yamaguchi, S1
Nakajima, M1
Aida, H1
Sakamoto, S1
Anzai, Y1
Watanabe, K1
Laitinen, P1
Happonen, JM1
Sairanen, H1
Peltola, K1
Rautiainen, P1
Damen, J1
Hitchcock, JF1
Burakovskiĭ, VI1
Bukharin, VA1

Trials

2 trials available for nitroglycerin and Transposition of Great Vessels

ArticleYear
Normal coronary flow reserve after arterial switch operation for transposition of the great arteries: an intracoronary Doppler guidewire study.
    Circulation, 2002, Sep-24, Volume: 106, Issue:13

    Topics: Adenosine; Blood Flow Velocity; Cardiac Catheterization; Child; Child, Preschool; Coronary Angiograp

2002
Amrinone versus dopamine and nitroglycerin in neonates after arterial switch operation for transposition of the great arteries.
    Journal of cardiothoracic and vascular anesthesia, 1999, Volume: 13, Issue:2

    Topics: Adrenergic Agonists; Amrinone; Blood Circulation; Cardiac Output; Cardiopulmonary Bypass; Cardiotoni

1999

Other Studies

4 other studies available for nitroglycerin and Transposition of Great Vessels

ArticleYear
Anesthetic management in the arterial switch "jatene" operation for transposition of the great arteries.
    Journal of cardiothoracic anesthesia, 1987, Volume: 1, Issue:6

    Topics: Adjuvants, Anesthesia; Anesthesia, General; Cardiopulmonary Bypass; Cardiovascular Surgical Procedur

1987
[Evaluation of intravenous nitroglycerin in the management of pulmonary hypertension in complete transposition of great vessels late after operation (author's transl)].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1982, Volume: 30, Issue:3

    Topics: Child, Preschool; Female; Humans; Hypertension, Pulmonary; Injections, Intravenous; Male; Nitroglyce

1982
Reactive pulmonary hypertension after a switch operation. Successful treatment with glyceryl trinitrate.
    British heart journal, 1985, Volume: 53, Issue:2

    Topics: Cardiopulmonary Bypass; Humans; Hypertension, Pulmonary; Infant; Male; Nitroglycerin; Transposition

1985
[Basic surgical problems in congenital heart defects].
    Kardiologiia, 1969, Volume: 9, Issue:10

    Topics: Age Factors; Aortic Coarctation; Aortic Valve Stenosis; Child; Child, Preschool; Heart Defects, Cong

1969