nitroglycerin has been researched along with Sleep Apnea, Obstructive in 8 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Obstructive sleep apnea is associated with increased cardiovascular morbidity and mortality." | 1.37 | Myocardial perfusion by myocardial contrast echocardiography and endothelial dysfunction in obstructive sleep apnea. ( Butt, M; Dwivedi, G; Khair, OA; Lip, GY; Shantsila, A; Shantsila, E, 2011) |
| " Dose-response curves to bradykinin and nitroglycerin were obtained from 12 subjects with OSAS and 12 matched control subjects." | 1.31 | Vascular reactivity in obstructive sleep apnea syndrome. ( Blaschke, TF; Duchna, HW; Faul, JL; Guilleminault, C; Hoffman, BB; Moreno, H; Stoohs, RA, 2000) |
| "Worsening nocturnal hypoxemia, measured as nocturnal oxygen saturation nadir or percentage of sleep time spent in hypoxemia (< 90% hemoglobin oxygen saturation), predicted increased interventricular septum thickness (corrected for age and body mass index), prolonged isovolumetric relaxation time, decreased ratio between peak early and late mitral flow velocities, as well as reduced endothelium-dependent dilatory capacity of the brachial artery (all relationships corrected for cofactor age and with p < 0." | 1.31 | Impairment of vascular endothelial function and left ventricular filling : association with the severity of apnea-induced hypoxemia during sleep. ( Caidahl, K; Hedner, J; Kraiczi, H; Peker, Y; Samuelsson, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, A | 1 |
| Vennelle, M | 1 |
| Connell, M | 1 |
| McKillop, G | 1 |
| Newby, DE | 1 |
| Douglas, NJ | 1 |
| Riha, RL | 1 |
| Nguyen, PK | 1 |
| Katikireddy, CK | 1 |
| McConnell, MV | 1 |
| Kushida, C | 1 |
| Yang, PC | 1 |
| Butt, M | 1 |
| Khair, OA | 1 |
| Dwivedi, G | 1 |
| Shantsila, A | 1 |
| Shantsila, E | 1 |
| Lip, GY | 1 |
| Grebe, M | 1 |
| Eisele, HJ | 1 |
| Weissmann, N | 1 |
| Schaefer, C | 1 |
| Tillmanns, H | 1 |
| Seeger, W | 1 |
| Schulz, R | 1 |
| Duchna, HW | 3 |
| Stoohs, R | 1 |
| Guilleminault, C | 3 |
| Christine Anspach, M | 1 |
| Schultze-Werninghaus, G | 2 |
| Orth, M | 2 |
| Stoohs, RA | 2 |
| Faul, JL | 1 |
| Moreno, H | 1 |
| Hoffman, BB | 1 |
| Blaschke, TF | 1 |
| Kraiczi, H | 1 |
| Caidahl, K | 1 |
| Samuelsson, A | 1 |
| Peker, Y | 1 |
| Hedner, J | 1 |
| de Zeeuw, J | 1 |
| Rasche, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Prevalence and Implications of Obstructive Sleep Apnea in the Population of a Wound Center[NCT00679757] | 300 participants (Actual) | Observational | 2008-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for nitroglycerin and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
The effect of continuous positive airway pressure therapy on arterial stiffness and endothelial function in obstructive sleep apnea: a randomized controlled trial in patients without cardiovascular disease.
Topics: Adrenergic beta-2 Receptor Agonists; Adult; Albuterol; Aorta; Blood Flow Velocity; Cardiovascular Di | 2013 |
Nasal continuous positive airway pressure improves myocardial perfusion reserve and endothelial-dependent vasodilation in patients with obstructive sleep apnea.
Topics: Adult; Aged; Asymptomatic Diseases; Brachial Artery; California; Cardiovascular Diseases; Continuous | 2010 |
6 other studies available for nitroglycerin and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Myocardial perfusion by myocardial contrast echocardiography and endothelial dysfunction in obstructive sleep apnea.
Topics: Acetylcholine; Adult; Blood Pressure; Brachial Artery; Continuous Positive Airway Pressure; Echocard | 2011 |
Antioxidant vitamin C improves endothelial function in obstructive sleep apnea.
Topics: Administration, Sublingual; Antioxidants; Ascorbic Acid; Brachial Artery; Endothelium, Vascular; Fem | 2006 |
Vascular endothelial dysfunction in patients with mild obstructive sleep apnea syndrome.
Topics: Adolescent; Adult; Aged; Atherosclerosis; Body Mass Index; Bradykinin; Continuous Positive Airway Pr | 2006 |
Vascular reactivity in obstructive sleep apnea syndrome.
Topics: Blood Pressure; Bradykinin; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Nitrog | 2000 |
Impairment of vascular endothelial function and left ventricular filling : association with the severity of apnea-induced hypoxemia during sleep.
Topics: Adult; Aged; Blood Flow Velocity; Brachial Artery; Cross-Sectional Studies; Diastole; Echocardiograp | 2001 |
[Obstructive sleep apnea syndrome: a cardiovascular risk factor?].
Topics: Bradykinin; Cardiovascular Diseases; Data Interpretation, Statistical; Endothelium, Vascular; Follow | 2001 |