Page last updated: 2024-11-01

nitroglycerin and Skin Ulcer

nitroglycerin has been researched along with Skin Ulcer in 5 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Skin Ulcer: An ULCER of the skin and underlying tissues.

Research Excerpts

ExcerptRelevanceReference
"The use of topical nitroglycerin has been reported to aid the healing of chronic skin ulcers."3.68The effect of topical nitroglycerin on transcutaneous oxygen. ( Alvarez, AF; Eaglstein, WH; Falanga, V; Katz, MH; Romanelli, M, 1991)
"In patients with systemic sclerosis (SSc), fingertip digital ulcers (DUs) are believed to be ischaemic, and extensor surface DUs a result of mechanical factors/microtrauma."2.84Reduced perfusion in systemic sclerosis digital ulcers (both fingertip and extensor) can be increased by topical application of glyceryl trinitrate. ( Dinsdale, G; Herrick, AL; Hughes, M; Manning, J; Moore, T; Murray, A; Roberts, C; Wilkinson, J, 2017)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
García-Gil, MF1
Lorda Espes, M1
Gracia-Cazaña, T1
Martínez García, A1
Ramirez-Lluch, M1
Monte Serrano, J1
Cruellas Lapeña, M1
Ara-Martín, M1
Hughes, M1
Moore, T1
Manning, J1
Wilkinson, J1
Dinsdale, G1
Roberts, C1
Murray, A1
Herrick, AL1
Wheeland, RG1
Gilchrist, RW1
Young, CJ1
Romanelli, M1
Katz, MH1
Alvarez, AF1
Eaglstein, WH1
Falanga, V1
Ahmad, S1

Trials

1 trial available for nitroglycerin and Skin Ulcer

ArticleYear
Reduced perfusion in systemic sclerosis digital ulcers (both fingertip and extensor) can be increased by topical application of glyceryl trinitrate.
    Microvascular research, 2017, Volume: 111

    Topics: Administration, Cutaneous; Adult; Aged; Blood Flow Velocity; Cross-Over Studies; Double-Blind Method

2017

Other Studies

4 other studies available for nitroglycerin and Skin Ulcer

ArticleYear
Cutaneous vasculopathy manifested as skin ulcers in neurofibromatosis.
    International journal of dermatology, 2020, Volume: 59, Issue:5

    Topics: Administration, Cutaneous; Adult; Back; Biopsy; Humans; Male; Neurofibromatosis 1; Nitroglycerin; Sk

2020
Treatment of ischemic digital ulcers with nitroglycerin ointment.
    The Journal of dermatologic surgery and oncology, 1983, Volume: 9, Issue:7

    Topics: Aged; Female; Fingers; Hand Dermatoses; Humans; Ischemia; Male; Middle Aged; Nitroglycerin; Ointment

1983
The effect of topical nitroglycerin on transcutaneous oxygen.
    The British journal of dermatology, 1991, Volume: 124, Issue:4

    Topics: Administration, Topical; Adult; Blood Gas Monitoring, Transcutaneous; Female; Humans; Male; Nitrogly

1991
Scleroderma and impotence: response to nitroglycerin applied to the fingers and penis.
    Southern medical journal, 1990, Volume: 83, Issue:12

    Topics: Adult; Erectile Dysfunction; Fingers; Humans; Male; Nitroglycerin; Penis; Scleroderma, Systemic; Ski

1990