nitroglycerin has been researched along with Pregnancy in 278 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 94 women with gestational hypertension and risk of intraoperative bleeding undergoing cesarean section were identified and randomized into the subcutaneous nitroglycerin group and control group." | 9.69 | Subcutaneous nitroglycerin increased the success rate of radial artery cannulation in women with gestational hypertension undergoing cesarean section : A randomized controlled trial. ( Chai, Y; Chen, P; Hu, WS; Men, X; Shou, HY; Wang, Q; Zhou, ZF, 2023) |
| " administration of nitroglycerine as an antihypertensive agent in the management of pre-eclampsia is scarce." | 9.13 | Efficacy of nitroglycerine infusion versus sublingual nifedipine in severe pre-eclampsia: a randomized, triple-blind, controlled trial. ( Gordillo-Moscoso, A; Hernández-Sierra, JF; Mandeville, PB; Manzur-Verástegui, S; Rodríguez-Martínez, M, 2008) |
| "Intravenous nitroglycerin and combined spinal-epidural anesthesia may offer an alternative to GA for achieving uterine relaxation in patients with PPP and a predicted difficult airway undergoing PTUI CS to control postpartum hemorrhage." | 9.05 | Use of nitroglycerin for parallel transverse uterine cesarean section in patients with pernicious placenta previa and placenta accrete and predicted difficult airway: A case report and review of literature. ( Jiang, X; Lin, X; Ma, Y; You, Y, 2020) |
| " The aim of this study was to analyze the sensitivity of rats with prenatal hyperhomocysteinemia (hHCY) in respect of the development of behavioral correlates of headache and spreading cortical depolarization (CSD) in a migraine model induced by the administration of the nitric oxide (NO) donor nitroglycerin." | 8.12 | Hyperhomocysteinemia Increases Cortical Excitability and Aggravates Mechanical Hyperalgesia and Anxiety in a Nitroglycerine-Induced Migraine Model in Rats. ( Bogatova, K; Enikeev, D; Gerasimova, E; Giniatullin, R; Hermann, A; Sitdikova, G; Yakovleva, O, 2022) |
| "To evaluate the effect of transdermal nitroglycerin on Doppler velocity waveforms of the uterine, umbilical and fetal middle cerebral arteries in patients with severe pre-eclampsia." | 7.77 | Transdermal nitroglycerin in patients with severe pre-eclampsia with placental insufficiency: effect on uterine, umbilical and fetal middle cerebral artery resistance indices. ( Gonçalves, LF; Pires, MM; Trapani, A, 2011) |
| "Intravenous ephedrine administered during a C-section was observed to cause an acute coronary syndrome in a pregnant woman with normal coronaries." | 7.72 | Acute coronary syndrome induced by intravenous ephedrine in pregnant woman with normal coronaries. ( Chamoun, A; Gedevanishvili, A; Rahman, AM; Uretsky, BF, 2004) |
| "To evaluate the effects and possibility of nitroglycerin on Pregnancy induced hypertension (PIH) treatment." | 7.71 | [Therapeutic effects of nitroglycerin on pregnancy induced hypertension]. ( Chen, D; Xu, H, 2001) |
| "During a 1-yr period, we evaluated prospectively the use of nitroglycerin (NTG) to relieve severe intrapartum fetal distress related to uterine hyperactivity." | 7.69 | Intravenous nitroglycerin to relieve intrapartum fetal distress related to uterine hyperactivity: a prospective observational study. ( Benhamou, D; Bouaziz, H; Dounas, M; Lhuissier, C; Mercier, FJ, 1997) |
| "Intravenous nitroglycerin would appear to be an ideal agent for the treatment of severe pregnancy-induced hypertension complicated by cardiogenic pulmonary edema." | 7.67 | Role of intravenous nitroglycerin in the treatment of severe pregnancy-induced hypertension complicated by pulmonary edema. ( Cotton, DB; Dorman, KF; Jones, MM; Joyce, TH; Longmire, S; Tessem, J, 1986) |
| "A total of 94 women with gestational hypertension and risk of intraoperative bleeding undergoing cesarean section were identified and randomized into the subcutaneous nitroglycerin group and control group." | 5.69 | Subcutaneous nitroglycerin increased the success rate of radial artery cannulation in women with gestational hypertension undergoing cesarean section : A randomized controlled trial. ( Chai, Y; Chen, P; Hu, WS; Men, X; Shou, HY; Wang, Q; Zhou, ZF, 2023) |
| "After these two UAE procedures, no recurrence of bleeding was observed." | 5.42 | Use of intra-arterial nitroglycerin during uterine artery embolization for severe postpartum hemorrhage with uterine artery vasospasm. ( Chiba, E; Hamamoto, K; Horiuchi, I; Matsuura, K; Mikami, Y; Okochi, T; Takagi, K; Wang, L, 2015) |
| "Although obstetric pulmonary edema is associated with extensive radiographic infiltrates and severe hypoxemia, resolution occurs rapidly in most patients, limiting the need for intensive care support." | 5.30 | Pulmonary edema in obstetric patients is rapidly resolved except in the presence of infection or of nitroglycerin tocolysis after open fetal surgery. ( Burlingame, JM; DiFederico, EM; Harrison, M; Kilpatrick, SJ; Matthay, MA, 1998) |
| "Seventeen patients with preeclampsia were treated with a nitroglycerin patch, 10 mg per 24 hours, for three consecutive days between 28 and 36 weeks' gestation." | 5.30 | Effects of transdermal nitroglycerin on impedance to flow in the uterine, umbilical, and fetal middle cerebral arteries in pregnancies complicated by preeclampsia and intrauterine growth retardation. ( Cacciatore, B; Halmesmäki, E; Kaaja, R; Teramo, K; Ylikorkala, O, 1998) |
| "25 micrograms/kg per minute with stepwise dosage increases until a diastolic blood pressure (BP) of 100 mmHg was achieved." | 5.29 | Effects of nitroglycerin on the uterine and umbilical circulation in severe preeclampsia. ( Carlström, K; Grunewald, C; Kublickas, M; Lunell, NO; Nisell, H, 1995) |
| " Because intravenous nitroglycerin is a potent, rapidly acting agent with a hemodynamic half-life measured in minutes, we evaluated its cardiovascular effects with and without volume expansion in six patients with severe pregnancy-induced hypertension." | 5.27 | Cardiovascular alterations in severe pregnancy-induced hypertension: effects of intravenous nitroglycerin coupled with blood volume expansion. ( Cotton, DB; Dorman, KF; Jones, MM; Joyce, TH; Longmire, S; Tessem, J, 1986) |
| " administration of nitroglycerine as an antihypertensive agent in the management of pre-eclampsia is scarce." | 5.13 | Efficacy of nitroglycerine infusion versus sublingual nifedipine in severe pre-eclampsia: a randomized, triple-blind, controlled trial. ( Gordillo-Moscoso, A; Hernández-Sierra, JF; Mandeville, PB; Manzur-Verástegui, S; Rodríguez-Martínez, M, 2008) |
| "Sublingual nitroglycerin was associated with a higher rate of headache and did not improve the rate of successful external cephalic version." | 5.10 | Sublingual nitroglycerin versus placebo as a tocolytic for external cephalic version: a randomized controlled trial in parous women. ( Berman, S; Boucher, M; Bujold, E; Ferreira, E; Marquette, GP; Rinfret, D, 2003) |
| "The object of this study was to compare intravaginal misoprostol and dinoprostone (prostaglandin E2) for second-trimester pregnancy termination, and to examine the role of the nitric oxide donor, glyceryl trinitrate, as a possible alternative to prostaglandins to induce cervical ripening in second-trimester pregnancy termination." | 5.10 | Second-trimester pregnancy termination: comparison of three different methods. ( Al-Hussaini, TK; Habib, DM; Makarem, MH; Makhlouf, AM, 2003) |
| "The mean time of pregnancy prolongation was 25 days in the nitroglycerin patch group, and 8 days in the magnesium sulfate and salbutamol sulfate group." | 5.10 | [Clinical effect and mechanism of nitroglycerin patch on arresting preterm labor]. ( Chen, X; Gu, H; Gu, Q; He, Q; Ning, H; Sha, J; Yang, Z, 2002) |
| "Nitric oxide (NO) and adrenomedullin (AM) are both involved in the regulation of fetoplacental circulation in human pregnancy." | 5.10 | Maternal nitric oxide supplementation increases adrenomedullin concentrations in growth retarded fetuses. ( Cosmi, EV; Di Iorio, R; Di Netta, T; Gazzolo, D; Letizia, C; Marinoni, E, 2002) |
| "The objective of the present study is to compare the effectiveness of transdermal glyceryl-trinitrate versus oral nifedipine in lowering blood pressure in patients affected by pregnancy-induced hypertension (PIH)." | 5.09 | 24-hour ambulatory blood pressure monitoring: a comparison between transdermal glyceryl-trinitrate and oral nifedipine. ( Facchinetti, F; Menghini, S; Neri, I; Romanini, C; Valensise, H; Volpe, A, 1999) |
| " Effectiveness of exogenic donator NO (transdermal nitroglycerine, Nitroderm NNS 5) was studied in a randomised trial of 76 gravidas with essential hypertension (EH), EH and chronic glomerulonephritis (GN)." | 5.08 | [Nitric oxide: its role in the development of pregnancy complications and in their prevention in women with hypertension and chronic glomerulonephritis]. ( Piatakova, NV; Rogov, VA; Tareeva, IE; Zozulia, OV, 1997) |
| "Intravenous nitroglycerin and combined spinal-epidural anesthesia may offer an alternative to GA for achieving uterine relaxation in patients with PPP and a predicted difficult airway undergoing PTUI CS to control postpartum hemorrhage." | 5.05 | Use of nitroglycerin for parallel transverse uterine cesarean section in patients with pernicious placenta previa and placenta accrete and predicted difficult airway: A case report and review of literature. ( Jiang, X; Lin, X; Ma, Y; You, Y, 2020) |
| " Nitroglycerin administration was not associated with an increase in headaches (RR 1." | 4.91 | Nitroglycerin for management of retained placenta. ( Abdel-Aleem, H; Abdel-Aleem, MA; Shaaban, OM, 2015) |
| "To evaluate the effectiveness of nitroglycerin as a uterine relaxant for preterm labour, fetal extraction at Caesarean section, external version, embryo transfer, cervical dilation for first trimester pregnancy termination, and primary dysmenorrhea." | 4.81 | Nitroglycerin as a uterine relaxant: a systematic review. ( Kung, R; Morgan, PJ; Tarshis, J, 2002) |
| " The aim of this study was to analyze the sensitivity of rats with prenatal hyperhomocysteinemia (hHCY) in respect of the development of behavioral correlates of headache and spreading cortical depolarization (CSD) in a migraine model induced by the administration of the nitric oxide (NO) donor nitroglycerin." | 4.12 | Hyperhomocysteinemia Increases Cortical Excitability and Aggravates Mechanical Hyperalgesia and Anxiety in a Nitroglycerine-Induced Migraine Model in Rats. ( Bogatova, K; Enikeev, D; Gerasimova, E; Giniatullin, R; Hermann, A; Sitdikova, G; Yakovleva, O, 2022) |
| " Administration of nitroglycerin at 200 μg to relax uterine smooth muscles and the application of fundal pressure led to severe bradycardia and loss of consciousness, followed by cardiac arrest." | 3.85 | Neurally Mediated Syncope During Cesarean Delivery: A Case Report. ( Kusumoto, G; Nakamori, E; Sato, S; Shigematsu, K; Yamaura, K, 2017) |
| "To evaluate the effect of transdermal nitroglycerin on Doppler velocity waveforms of the uterine, umbilical and fetal middle cerebral arteries in patients with severe pre-eclampsia." | 3.77 | Transdermal nitroglycerin in patients with severe pre-eclampsia with placental insufficiency: effect on uterine, umbilical and fetal middle cerebral artery resistance indices. ( Gonçalves, LF; Pires, MM; Trapani, A, 2011) |
| " Careful titration of dosage is required (beginning at 5 micrograms/min), and if the infusion sets contain polyvinylchloride, the delivered dose is lower than that calculated, because of adsorption of glyceryl trinitrate onto the plastic tubing." | 3.75 | Intravenous glyceryl trinitrate (nitroglycerin). A review of its pharmacological properties and therapeutic efficacy. ( Brogden, RN; Romankiewicz, JA; Sorkin, EM, 1984) |
| "To report the use of regional anesthesia and iv nitroglycerin to provide anesthesia and uterine relaxation for three Cesarean deliveries (CD) involving ex utero intrapartum treatment (EXIT) of potentially life-threatening airway obstruction in the newborn." | 3.74 | Case series: Combined spinal epidural anesthesia for Cesarean delivery and ex utero intrapartum treatment procedure. ( George, RB; Habib, AS; Melnick, AH; Rose, EC, 2007) |
| " General anesthesia was maintained with sevoflurane 2%, combined with continuous infusion of nitroglycerine (TNG)." | 3.74 | The use of potent inhalational agents for the ex- utero intrapartum treatment (exit) procedures: what concentrations? ( Kuczkowski, KM; Okutomi, T; Saito, M, 2007) |
| "The uterus at premature birth being thick and sensitive, we applied nitroglycerin (NTG) to relax the uterus during cesarean delivery for the low birthweight baby." | 3.73 | [Nitroglycerin to relax the uterus during cesarean delivery for the low birthweight baby]. ( Tsutsui, T, 2005) |
| "We studied the effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam (a dopamine D1-agonist) on isolated human umbilical arteries (HUA) from patients classified as normotensive and with pregnancy-induced hypertension (PIH)." | 3.72 | The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery. ( Arias, ME; Levy, JH; Sato, N; Szlam, F; Tanaka, KA; Tsuda, A, 2003) |
| "Intravenous ephedrine administered during a C-section was observed to cause an acute coronary syndrome in a pregnant woman with normal coronaries." | 3.72 | Acute coronary syndrome induced by intravenous ephedrine in pregnant woman with normal coronaries. ( Chamoun, A; Gedevanishvili, A; Rahman, AM; Uretsky, BF, 2004) |
| "To evaluate the effects and possibility of nitroglycerin on Pregnancy induced hypertension (PIH) treatment." | 3.71 | [Therapeutic effects of nitroglycerin on pregnancy induced hypertension]. ( Chen, D; Xu, H, 2001) |
| "In order to explore the role of nitric oxide (NO) in the control of fetoplacental vascular tone in normal pregnancy we have examined the effects of NO donors on uteroplacental arteries pre-contracted with the vasoconstrictor endothelin-1 (ET-1) or serotonin (5-HT)." | 3.71 | Effects of nitric oxide donors and inhibitors of nitric oxide signalling on endothelin- and serotonin-induced contractions in human placental arteries. ( Andersson, E; Fried, G; Sand, AE, 2002) |
| "Diethylamine-nitric oxide and nitroglycerin inhibited spontaneous uterine contractions in rings from midpregnancy, in both the absence and the presence of placenta." | 3.70 | Effect of placental tissue on inhibition of uterine contraction by nitric oxide donors. ( Chwalisz, K; Garfield, RE; Okawa, T; Saade, GR; Syal, A; Vedernikov, Y, 1999) |
| "To our knowledge, this is the first time that a combination of aspirin and glyceryl trinitrate (GTN) has been used in the prophylaxis of preeclampsia and fetal growth retardation, and their use associated with not only Doppler screening of the uterine arteries but also regular Doppler follow-up of the fetal arterial and venous circulation." | 3.70 | A novel approach to the management of pregnancies complicated by uteroplacental insufficiency and previous stillbirth. ( Black, RS; Campbell, S; Lees, CC; Oyelese, KO, 1998) |
| "During a 1-yr period, we evaluated prospectively the use of nitroglycerin (NTG) to relieve severe intrapartum fetal distress related to uterine hyperactivity." | 3.69 | Intravenous nitroglycerin to relieve intrapartum fetal distress related to uterine hyperactivity: a prospective observational study. ( Benhamou, D; Bouaziz, H; Dounas, M; Lhuissier, C; Mercier, FJ, 1997) |
| "Intravenous nitroglycerin would appear to be an ideal agent for the treatment of severe pregnancy-induced hypertension complicated by cardiogenic pulmonary edema." | 3.67 | Role of intravenous nitroglycerin in the treatment of severe pregnancy-induced hypertension complicated by pulmonary edema. ( Cotton, DB; Dorman, KF; Jones, MM; Joyce, TH; Longmire, S; Tessem, J, 1986) |
| "The effects of nitroglycerin (TNG) and sodium nitroprusside (SNP) on mean aortic pressure (MAP), uterine blood flow (UBF), uterine vascular conductance (UVC), and pulse rate (PR) were compared when the two agents were infused to prevent and treat hypertension induced by norepinephrine (NE) in gravid ewes." | 3.66 | Effects of nitroglycerin and nitroprusside on the uterine vasculature of gravid ewes. ( Dewan, DM; Fishburne, JI; Greiss, FC; James, FM; Meis, PJ; Rose, JC; Urban, RB; Wheeler, AS, 1980) |
| "Nitroglycerin in aqueous solution has been used as hypotensive agent during a caesarean section, in a patient who presented an arterial hypertension not controled by administration of four antihypertensive agents (acebutolol, clonidine, dihydralazine, alpha-methyl-dopa)." | 3.66 | [Clinical use of nitroglycerin as an hypotensive agent during general anesthesia for caesarean section. Report of a case (author's transl)]. ( Chelly, J; Delarrat, M; Garcia, A; Kergrohen, F; Passelecq, J, 1980) |
| "Nitroglycerin groups were exposed to incremental concentrations of nitroglycerin, while no nitroglycerin groups were kept in control (physiological salt) solution." | 3.01 | The Effects of Nitroglycerin on the Oxytocin Dose-Response Profile in Oxytocin-Desensitized and Naïve Human Myometrium: An In Vitro Study. ( Balki, M; Carvalho, JCA; Jayasooriya, GS; Luca, A, 2021) |
| "Currently, the only effective treatments for a retained placenta are the surgical procedures of manual removal of placenta (MROP) and uterine curettage, which are not universally available, particularly in low- and middle-income countries." | 2.90 | Nitroglycerin for treatment of retained placenta: A randomised, placebo-controlled, multicentre, double-blind trial in the UK. ( Brewin, J; Carruthers, KF; Chua, GN; Denison, FC; Hallowell, N; Hudson, J; Lawton, J; McPherson, G; Norman, JE; Norrie, J; Peace, M; Scotland, G, 2019) |
| "The only way to treat a retained placenta is for a trained doctor to remove it by an operation in theatre." | 2.90 | Glyceryl trinitrate to reduce the need for manual removal of retained placenta following vaginal delivery: the GOT-IT RCT. ( Brewin, J; Brook-Smith, S; Carruthers, KF; Chua, GN; Clarkson, C; Denison, FC; Hallowell, N; Hudson, J; Lawton, J; McPherson, G; Norman, JE; Norrie, J; Peace, M; Scotland, G, 2019) |
| "A retained placenta is diagnosed when the placenta is not delivered following delivery of the baby." | 2.84 | A pragmatic group sequential, placebo-controlled, randomised trial to determine the effectiveness of glyceryl trinitrate for retained placenta (GOT-IT): a study protocol. ( Brewin, J; Brook-Smith, S; Carruthers, KF; Clarkson, C; Denison, FC; Forrest, M; Hallowell, N; Hodges, L; Hudson, J; Lawton, J; McDonald, A; McPherson, GC; Morrow, S; Norman, JE; Norrie, J; Peace, M; Scotland, G, 2017) |
| "Management of preterm labor and prevention from preterm delivery in order to lower these risks have always been under serious concern." | 2.79 | Comparison between nitroglycerin dermal patch and nifedipine for treatment of preterm labor: a randomized clinical trial. ( Kashanian, M; Sheikhansari, N; Zamen, Z, 2014) |
| "The rates of successful removal of the retained placenta in the study (n=20) and control (n=20) groups were compared, as were blood pressure, pulse rate, blood loss, and adverse effects." | 2.76 | Intravenous nitroglycerin for controlled cord traction in the management of retained placenta. ( Permpolprasert, L; Prechapanich, J; Suksopee, P; Suwanvichai, S; Visalyaputra, S; Yimyam, S, 2011) |
| "A common approach in the management of retained placenta is administration of oxytocin followed by controlled cord traction." | 2.73 | Sublingual nitroglycerin seems to be effective in the management of retained placenta. ( Bullarbo, M; Ekerhovd, E, 2008) |
| "Terbutaline resulted in lower median contraction frequency per 10 minutes (2." | 2.73 | Randomized comparison of intravenous terbutaline vs nitroglycerin for acute intrapartum fetal resuscitation. ( Caughey, AB; Druzin, ML; El-Sayed, YY; Pullen, KM; Riley, ET; Taylor, L; Waller, SA, 2007) |
| " Outcome parameters were (1) the effects on fetal and maternal heart frequency (FHF/MHF) and blood pressure, and (2) subjective experiences of adverse effects assessed by utilising a questionnaire." | 2.71 | Maternal and fetal side effects of tocolysis using transdermal nitroglycerin or intravenous fenoterol combined with magnesium sulfate. ( Gross, W; Kähler, C; Möller, A; Möller, U; Richter, S; Schleussner, E; Seewald, HJ, 2003) |
| "Fifty five women with preeclampsia, eclampsia, and HELLP syndrome administered GTN infusion for the management of hypertension were studied." | 2.71 | The effect of glyceryl trinitrate on hypertension in women with severe preeclampsia, HELLP syndrome, and eclampsia. ( Cetin, A; Cetin, M; Duran, B; Guvenal, T; Imir, AG; Yurtcu, N, 2004) |
| "Women in threatened preterm labor with positive fetal fibronectin or ruptured membranes between 24 and 35 weeks' gestation were recruited and randomly assigned to either beta2 or GTN with rescue beta2 tocolysis if moderate-to-strong contractions persisted at 2 hours." | 2.71 | The Randomized Nitric Oxide Tocolysis Trial (RNOTT) for the treatment of preterm labor. ( Bisits, A; Cheung, K; Chung, T; Daniel, M; Giles, W; Gill, A; Jones, I; Knox, M; Kwek, K; Leung, TN; Madsen, G; Smith, R; Toohill, J; Tudehope, D; Yeo, G, 2004) |
| "Sublingual nitroglycerin for treatment of retained placenta seems to be effective without causing serious adverse effects." | 2.71 | Sublingual nitroglycerin for management of retained placenta. ( Bullarbo, M; Ekerhovd, E; Tjugum, J, 2005) |
| "Two hundred forty-five women with preterm labor and intact membranes between 24 and 36 weeks' gestation were randomized to transdermal glyceryl trinitrate or intravenous ritodrine." | 2.69 | Glyceryl trinitrate and ritodrine in tocolysis: an international multicenter randomized study. GTN Preterm Labour Investigation Group. ( Black, RS; Campbell, S; Danti, L; Lees, CC; Lojacono, A; Tanzi, P; Thompson, C; White, IR, 1999) |
| "Twenty-six consecutive patients with preterm labor were randomized to tocolytic treatment with transdermal glyceryl trinitrate (n=13) or intravenous albuterol (n=13)." | 2.69 | Corticotropin-releasing hormone: a biochemical predictor of preterm delivery in a pilot randomized trial of the treatment of preterm labor. ( Bisits, A; Giles, W; Madsen, G; McLean, M; O'Callaghan, S; Smith, R, 1998) |
| " The aim of this study was to determine whether pre-eclampsia and its complications could be prevented by the long-term use of nitric oxide donors in a group of women identified to be at risk on the basis of abnormal uterine artery Doppler measurements." | 2.69 | The efficacy and fetal-maternal cardiovascular effects of transdermal glyceryl trinitrate in the prophylaxis of pre-eclampsia and its complications: a randomized double-blind placebo-controlled trial. ( Black, R; Byiers, S; Campbell, S; Harrington, K; Lees, C; Romanini, C; Valensise, H, 1998) |
| "Nitroglycerin was administered as a 100-microg bolus, then at a rate of 1- to 10-microg/kg/min." | 2.69 | Randomized comparison of intravenous nitroglycerin and magnesium sulfate for treatment of preterm labor. ( Chitkara, U; Cohen, SE; Druzin, ML; El-Sayed, YY; Holbrook, RH; Riley, ET, 1999) |
| "Breech presentation is associated with increased complications." | 2.52 | Interventions for helping to turn term breech babies to head first presentation when using external cephalic version. ( Cluver, C; Dowswell, T; Gyte, GM; Hofmeyr, GJ; Sinclair, M, 2015) |
| " Although not causal, endothelial dysfunction and reduced nitric oxide bioavailability are likely to play an important role in the maternal and fetal pathophysiology of this condition." | 2.50 | The nitric oxide pathway and possible therapeutic options in pre-eclampsia. ( Everett, TR; Johal, T; Lees, CC; Wilkinson, IB, 2014) |
| "Breech presentation is associated with increased complications." | 2.48 | Interventions for helping to turn term breech babies to head first presentation when using external cephalic version. ( Cluver, C; Gyte, GM; Hofmeyr, GJ; Sinclair, M, 2012) |
| "Retained placenta affects 0." | 2.47 | Tocolysis for management of retained placenta. ( Abdel-Aleem, H; Abdel-Aleem, MA; Shaaban, OM, 2011) |
| " However, the preferred type of beta-adrenergic receptor agonist and dosage are unclear." | 2.44 | Acute tocolysis for uterine activity reduction in term labor: a review. ( de Heus, R; Derks, JB; Mulder, EJ; Visser, GH, 2008) |
| "Nitroglycerin has been used successfully as an acute tocolytic during Caesarean sections and manual removal of placenta." | 2.43 | Acute tocolysis. ( Arulkumaran, S; Chandraharan, E, 2005) |
| "Nitroglycerine was the NO donor used in all these trials." | 2.41 | Nitric oxide donors for the treatment of preterm labour. ( Duckitt, K; Thornton, S, 2002) |
| " These drugs must be administered parenterally and have a half-life of only a few minutes." | 2.40 | Clinical pharmacokinetics of vasodilators. Part II. ( Heintz, B; Kirsten, D; Kirsten, R; Nelson, K, 1998) |
| " The present data suggest that the oxidative stress and reduced bioavailability of nitric oxide may contribute to attenuation of vasodilator responses to ACh and Ang II, and hyperreactivity to Ang II in the mesentery of preeclamptic rat, which may contribute to the increased peripheral vascular resistance and BP, as well as intrauterine growth restriction in L-NAME-induced PE." | 1.48 | Differential responses of mesenteric arterial bed to vasoactive substances in L-NAME-induced preeclampsia: Role of oxidative stress and endothelial dysfunction. ( Amaral, TAS; Carvalho, LCRM; Costa, CA; Moura, RS; Ognibene, DT; Resende, AC; Rocha, APM, 2018) |
| "After these two UAE procedures, no recurrence of bleeding was observed." | 1.42 | Use of intra-arterial nitroglycerin during uterine artery embolization for severe postpartum hemorrhage with uterine artery vasospasm. ( Chiba, E; Hamamoto, K; Horiuchi, I; Matsuura, K; Mikami, Y; Okochi, T; Takagi, K; Wang, L, 2015) |
| "A nitroglycerin tablet was used to relax the lower uterine segment and cervix, which allowed the placenta to pass through the cervix for delivery." | 1.39 | A novel treatment for management of a trapped placenta using intracervical nitroglycerin tablets. ( Gray, R; Pasternak, A; Rodgers, BC, 2013) |
| "The antenatal diagnosis of aortic dissection carries a grave prognosis." | 1.39 | Successful management of aortic dissection in a patient with Marfan syndrome during pregnancy. ( Chang, CY; Chen, PH; Lam, CW; Yang, JM, 2013) |
| "The incidence and importance of retained placenta (RP) varies greatly around the world." | 1.35 | The retained placenta. ( Weeks, AD, 2008) |
| "Postpartum haemorrhage due to retained placenta is one of the commonest life-threatening conditions during the third stage of labour." | 1.32 | Intravenous nitro-glycerine versus general anaesthesia for placental extraction--a sequential comparison. ( Chiu, JW; Jha, S; Yeo, IS, 2003) |
| "Twenty-five pregnant women who received GTN patches (Nitroderm TTS 10) with a dosage of 0." | 1.32 | Nitric oxide donors: effects on fetoplacental blood flow. ( Kähler, C; Möller, A; Schleussner, E; Seewald, HJ, 2004) |
| "A total of 113 women with previous preeclampsia (n = 35 with recurrent episodes; n = 78 with a single episode) and 48 women with previous uncomplicated pregnancies, all of whom were at least 3 months (median, 3 years) postpartum." | 1.31 | Association of maternal endothelial dysfunction with preeclampsia. ( Chambers, JC; De Swiet, M; Fusi, L; Haskard, DO; Kooner, JS; Malik, IS, 2001) |
| "The use of beta blockers during treatment of mitral stenosis is discussed on four cases involving females patients who are symptomatic." | 1.30 | [Role of beta-blockers in the treatment of mitral stenosis, apropos of 4 cases]. ( Ba, SA; Diop, IB; Diouf, SM; Fall, MD; Hane, L; Kane, A; Sarr, M, 1997) |
| "Nitroglycerin was infused maternally over 30 minutes at 1." | 1.30 | Fetal and maternal hemodynamic and metabolic effects of maternal nitroglycerin infusions in sheep. ( Bootstaylor, BS; Heymann, MA; Parer, JT; Roman, C, 1997) |
| "Nitroglycerin (TNG) has recently gained popularity in obstetric anesthesia for facilitating acute uterine relaxation in the treatment of obstetric emergencies such as retained placenta." | 1.30 | Placental tissue enhances uterine relaxation by nitroglycerin. ( Csavoy, AN; Datta, S; Segal, S, 1998) |
| "Seventeen patients with preeclampsia were treated with a nitroglycerin patch, 10 mg per 24 hours, for three consecutive days between 28 and 36 weeks' gestation." | 1.30 | Effects of transdermal nitroglycerin on impedance to flow in the uterine, umbilical, and fetal middle cerebral arteries in pregnancies complicated by preeclampsia and intrauterine growth retardation. ( Cacciatore, B; Halmesmäki, E; Kaaja, R; Teramo, K; Ylikorkala, O, 1998) |
| "Although obstetric pulmonary edema is associated with extensive radiographic infiltrates and severe hypoxemia, resolution occurs rapidly in most patients, limiting the need for intensive care support." | 1.30 | Pulmonary edema in obstetric patients is rapidly resolved except in the presence of infection or of nitroglycerin tocolysis after open fetal surgery. ( Burlingame, JM; DiFederico, EM; Harrison, M; Kilpatrick, SJ; Matthay, MA, 1998) |
| "Pregnancy was managed to term before she progressed to NYHA Class IV and cardiac failure at 37 wk gestation." | 1.30 | Cesarean section in a mother with uncorrected congenital coronary to pulmonary artery fistula. ( Ong, BC; Tan, SA; Tay, SM, 1999) |
| "Nitroglycerin infusion caused a significant increase in maternal and fetal heart rate and a significant decrease in maternal and fetal mean arterial pressure at a dosage of 10 microram/kg per minute, without a change in blood gas values." | 1.30 | Effects of nitroglycerin and indomethacin on fetal-maternal circulation and on fetal cerebral blood flow and metabolism in sheep. ( Harrison, MR; Heymann, MA; Morris, JA; Roman, C; Skarsgard, ED; VanderWall, KJ, 1999) |
| "The diagnosis of increased permeability pulmonary edema was confirmed by the ratio of pulmonary edema fluid to plasma protein (ratio=0." | 1.29 | Pulmonary edema in a woman following fetal surgery. ( DiFederico, EM; Harrison, M; Matthay, MA, 1996) |
| "Histamine contractions were enhanced in endothelium-intact strips in the presence of 10 mumol/L L-NG-nitro arginine (competitive inhibitor of nitric oxide synthase) but not in the presence of 10 mumol/L indomethacin (cyclooxygenase inhibitor)." | 1.29 | Comparison of nitric oxide and prostacyclin in endothelium-dependent vasorelaxation of human umbilical artery at midgestation. ( Garfield, RE; Izumi, H; Makino, Y; Mohtai, H; Shirakawa, K, 1996) |
| "25 micrograms/kg per minute with stepwise dosage increases until a diastolic blood pressure (BP) of 100 mmHg was achieved." | 1.29 | Effects of nitroglycerin on the uterine and umbilical circulation in severe preeclampsia. ( Carlström, K; Grunewald, C; Kublickas, M; Lunell, NO; Nisell, H, 1995) |
| "Nitroglycerin (NTG) has been demonstrated to provide uterine relaxation in the management of various obstetric complications." | 1.29 | Alternating nitroglycerin and syntocinon to facilitate uterine exploration and removal of an adherent placenta. ( Ananthanarayan, C; Chan, AS; Rolbin, SH, 1995) |
| "These signs are similar to those of preeclampsia and indicate that an alteration in nitric oxide synthesis may be one of the factors responsible for this disorder." | 1.29 | Inhibition of nitric oxide synthesis in rats during pregnancy produces signs similar to those of preeclampsia. ( Garfield, RE; Yallampalli, C, 1993) |
| "In severe preeclampsia absence of lactate-induced dilatation of placental vessels may contribute to the fetal complications associated with impaired blood flow and vasospasm." | 1.29 | Absence of relaxation to lactate in human placental vessels of pregnancies with severe preeclampsia. ( Fayngersh, RP; Figueroa, R; Jiang, H; Martinez, E; Omar, HA; Tejani, N; Wolin, MS, 1995) |
| "Myocardial infarction is encountered rarely during pregnancy, but when it occurs the event is life-threatening to both mother and fetus." | 1.28 | Anaesthetic management of myocardial infarction in a parturient. ( Aglio, LS; Johnson, MD, 1990) |
| " Because intravenous nitroglycerin is a potent, rapidly acting agent with a hemodynamic half-life measured in minutes, we evaluated its cardiovascular effects with and without volume expansion in six patients with severe pregnancy-induced hypertension." | 1.27 | Cardiovascular alterations in severe pregnancy-induced hypertension: effects of intravenous nitroglycerin coupled with blood volume expansion. ( Cotton, DB; Dorman, KF; Jones, MM; Joyce, TH; Longmire, S; Tessem, J, 1986) |
| "When nitroglycerin was administered during oxygen-stimulated ductal closure, ductal blood flow increased 184%, from 79 +/- 18 to 225 +/- 18 ml/min (P less than 0." | 1.27 | Response of lamb ductus arteriosus to nitroglycerin and nitroprusside. ( Ely, SW; Mentzer, RM; Walsh, RS, 1988) |
| "Nitroglycerin was detected in all but two samples of foetal arterial blood but the foetal/maternal artery ratio was only 0." | 1.26 | Plasma levels and cardiovascular effect of nitroglycerin in pregnant sheep. ( Busch, MD; de Rosayro, M; Hill, AB; Kirsh, MM; Nahrwold, ML; Tait, AR, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (14.39) | 18.7374 |
| 1990's | 91 (32.73) | 18.2507 |
| 2000's | 97 (34.89) | 29.6817 |
| 2010's | 42 (15.11) | 24.3611 |
| 2020's | 8 (2.88) | 2.80 |
| Authors | Studies |
|---|---|
| Gerasimova, E | 1 |
| Yakovleva, O | 1 |
| Enikeev, D | 1 |
| Bogatova, K | 1 |
| Hermann, A | 1 |
| Giniatullin, R | 1 |
| Sitdikova, G | 1 |
| Men, X | 1 |
| Wang, Q | 1 |
| Chen, P | 1 |
| Hu, WS | 1 |
| Chai, Y | 1 |
| Shou, HY | 1 |
| Zhou, ZF | 1 |
| Pels, A | 1 |
| Ganzevoort, W | 1 |
| Kenny, LC | 1 |
| Baker, PN | 1 |
| von Dadelszen, P | 1 |
| Gluud, C | 1 |
| Kariya, CT | 1 |
| Leemhuis, AG | 1 |
| Groom, KM | 2 |
| Sharp, AN | 1 |
| Magee, LA | 1 |
| Jakobsen, JC | 1 |
| Mol, BWJ | 1 |
| Papageorghiou, AT | 1 |
| Denison, FC | 3 |
| Carruthers, KF | 3 |
| Hudson, J | 3 |
| McPherson, G | 2 |
| Chua, GN | 2 |
| Peace, M | 3 |
| Brewin, J | 3 |
| Hallowell, N | 3 |
| Scotland, G | 3 |
| Lawton, J | 3 |
| Norrie, J | 3 |
| Norman, JE | 5 |
| Brook-Smith, S | 2 |
| Clarkson, C | 2 |
| Ma, Y | 1 |
| You, Y | 1 |
| Jiang, X | 1 |
| Lin, X | 1 |
| Jayasooriya, GS | 1 |
| Carvalho, JCA | 1 |
| Luca, A | 1 |
| Balki, M | 1 |
| Yoon, SW | 1 |
| Choi, GJ | 1 |
| Seong, HK | 1 |
| Lee, MJ | 1 |
| Kang, H | 1 |
| Takakura, S | 1 |
| Tanaka, H | 1 |
| Enomoto, N | 1 |
| Maki, S | 1 |
| Ikeda, T | 1 |
| Robb, KP | 1 |
| Cotechini, T | 2 |
| Allaire, C | 1 |
| Sperou, A | 1 |
| Graham, CH | 6 |
| Amaral, TAS | 1 |
| Ognibene, DT | 1 |
| Carvalho, LCRM | 1 |
| Rocha, APM | 1 |
| Costa, CA | 1 |
| Moura, RS | 1 |
| Resende, AC | 1 |
| McPherson, GC | 1 |
| McDonald, A | 1 |
| Forrest, M | 1 |
| Morrow, S | 1 |
| Hodges, L | 1 |
| Gu, Z | 1 |
| Xin, L | 1 |
| Wang, Z | 1 |
| Wang, J | 1 |
| Leathersich, SJ | 1 |
| Vogel, JP | 1 |
| Tran, TS | 1 |
| Hofmeyr, GJ | 3 |
| Dinges, E | 1 |
| Heier, J | 1 |
| Delgado, C | 1 |
| Bollag, L | 1 |
| Cananzi, SG | 1 |
| Mayhan, WG | 1 |
| Katz, D | 1 |
| Riley, K | 1 |
| Kim, E | 1 |
| Beilin, Y | 1 |
| Nazarov, SB | 2 |
| Ivanova, AS | 2 |
| Novikov, AA | 2 |
| Matsuda, C | 1 |
| Hayashi, S | 1 |
| Kinouchi, K | 1 |
| Conde-Agudelo, A | 1 |
| Romero, R | 1 |
| Arulkumaran, N | 1 |
| Lightstone, L | 1 |
| Rodgers, BC | 1 |
| Pasternak, A | 1 |
| Gray, R | 1 |
| Johal, T | 1 |
| Lees, CC | 3 |
| Everett, TR | 1 |
| Wilkinson, IB | 1 |
| Duckitt, K | 2 |
| Thornton, S | 2 |
| O'Donovan, OP | 1 |
| Dowswell, T | 2 |
| Kashanian, M | 2 |
| Zamen, Z | 1 |
| Sheikhansari, N | 2 |
| Duffy, JM | 1 |
| Wilson, MJ | 1 |
| Khan, KS | 1 |
| Cluver, C | 2 |
| Gyte, GM | 2 |
| Sinclair, M | 2 |
| Wang, L | 1 |
| Horiuchi, I | 1 |
| Mikami, Y | 1 |
| Takagi, K | 1 |
| Okochi, T | 1 |
| Hamamoto, K | 1 |
| Chiba, E | 1 |
| Matsuura, K | 1 |
| Trapani, A | 2 |
| Gonçalves, LF | 2 |
| Trapani, TF | 1 |
| Franco, MJ | 1 |
| Galluzzo, RN | 1 |
| Pires, MM | 2 |
| Abdel-Aleem, H | 2 |
| Abdel-Aleem, MA | 2 |
| Shaaban, OM | 2 |
| Ardekani, S | 1 |
| Scott, HA | 1 |
| Gupta, S | 1 |
| Eum, S | 1 |
| Yang, X | 1 |
| Brunelle, AR | 1 |
| Wilson, SM | 1 |
| Mohideen, U | 1 |
| Ghosh, K | 1 |
| Hasankhani, S | 1 |
| Bahasadri, S | 1 |
| Homam, H | 1 |
| Iacobaeus, C | 1 |
| Kahan, T | 1 |
| Jörneskog, G | 1 |
| Bremme, K | 1 |
| Thorsell, M | 1 |
| Andolf, E | 1 |
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| Henry, D | 1 |
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| Moghadassi, M | 1 |
| Thiet, MP | 1 |
| Norton, M | 1 |
| Lucero, J | 1 |
| Sasano, T | 1 |
| Tomimatsu, T | 1 |
| Kanagawa, T | 1 |
| Kimura, T | 1 |
| Sato, S | 1 |
| Nakamori, E | 1 |
| Kusumoto, G | 1 |
| Shigematsu, K | 1 |
| Yamaura, K | 1 |
| Clift, K | 1 |
| Clift, J | 1 |
| Weeks, AD | 1 |
| Fornet, I | 1 |
| Ortiz-Gómez, JR | 1 |
| Palacio, FJ | 1 |
| López, MA | 1 |
| Gandhi, MN | 1 |
| Mahajan, NN | 1 |
| Iyer, HR | 1 |
| Shirodkar, SD | 1 |
| Hilton, J | 1 |
| Allan, B | 1 |
| Swaby, C | 1 |
| Wah, R | 1 |
| Jarrell, J | 1 |
| Wood, S | 1 |
| Ross, S | 1 |
| Tran, Q | 1 |
| Pàez, O | 1 |
| Alfie, J | 1 |
| Gorosito, M | 1 |
| Puleio, P | 1 |
| de Maria, M | 1 |
| Prieto, N | 1 |
| Majul, C | 1 |
| Amorim, MM | 1 |
| Lippo, LA | 1 |
| Costa, AA | 1 |
| Coutinho, IC | 1 |
| Souza, AS | 1 |
| Holzgreve, H | 2 |
| Smith, GN | 9 |
| Guo, Y | 2 |
| Wen, SW | 2 |
| Walker, MC | 4 |
| Visalyaputra, S | 1 |
| Prechapanich, J | 1 |
| Suwanvichai, S | 1 |
| Yimyam, S | 1 |
| Permpolprasert, L | 1 |
| Suksopee, P | 1 |
| Xie, R | 1 |
| Ioscovich, A | 1 |
| Shen, O | 1 |
| Sichel, JY | 1 |
| Lajos, Y | 1 |
| Orkin, D | 1 |
| Bromiker, R | 1 |
| Briskin, A | 1 |
| Barsoum, IB | 1 |
| Renaud, SJ | 1 |
| Espinoza, J | 1 |
| Espinoza, AF | 1 |
| Othman, M | 1 |
| Shaikh, S | 1 |
| Shaikh, AH | 1 |
| Akhter, S | 1 |
| Isran, B | 1 |
| Chang, CY | 1 |
| Yang, JM | 1 |
| Lam, CW | 1 |
| Chen, PH | 1 |
| Buhimschi, CS | 1 |
| Buhimschi, IA | 1 |
| Malinow, AM | 1 |
| Weiner, CP | 1 |
| Ezra, Y | 1 |
| Wade, C | 1 |
| Rolbin, SH | 3 |
| Farine, D | 1 |
| Di Iorio, R | 1 |
| Marinoni, E | 1 |
| Gazzolo, D | 1 |
| Letizia, C | 1 |
| Di Netta, T | 1 |
| Cosmi, EV | 1 |
| Morgan, PJ | 1 |
| Kung, R | 1 |
| Tarshis, J | 1 |
| Wang, CH | 1 |
| Li, ZY | 1 |
| Xiao, GX | 1 |
| Ohl, J | 1 |
| Lefèbvre-Maunoury, C | 1 |
| Wittemer, C | 1 |
| Nisand, G | 1 |
| Laurent, MC | 1 |
| Hoffmann, P | 1 |
| Leszczyńska-Gorzelak, B | 3 |
| Laskowska, M | 3 |
| Marciniak, B | 3 |
| Oleszczuk, J | 3 |
| Schleussner, E | 2 |
| Möller, A | 2 |
| Gross, W | 1 |
| Kähler, C | 2 |
| Möller, U | 1 |
| Richter, S | 1 |
| Seewald, HJ | 2 |
| Sato, N | 1 |
| Tanaka, KA | 1 |
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| Tsuda, A | 1 |
| Arias, ME | 1 |
| Levy, JH | 1 |
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| Sergerie, M | 1 |
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| Bédard, MJ | 1 |
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| Väisänen-Tommiska, M | 1 |
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| Aittomäki, K | 1 |
| Hiilesmaa, V | 1 |
| Ylikorkala, O | 2 |
| Ma, SX | 1 |
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| Marquette, GP | 2 |
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| Gauthier, RJ | 1 |
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| Makhlouf, AM | 1 |
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| BRILL, HM | 1 |
| LONG, JS | 1 |
| KLAWANS, AH | 1 |
| GOLDEN, M | 1 |
| SEAMAN, I | 1 |
| MORRIS, N | 1 |
| TOMKINSON, JS | 1 |
| O'CONNOR, BJ | 1 |
| RODDICK, JW | 1 |
| BENARON, HB | 1 |
| GARDINER, J | 1 |
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| GAUTIERI, RF | 3 |
| CHRISTIE, RW | 1 |
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| Saade, GR | 4 |
| Garfield, RE | 7 |
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| Chan, AS | 1 |
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| Omar, HA | 2 |
| Figueroa, R | 3 |
| Tejani, N | 3 |
| Wolin, MS | 3 |
| Lees, C | 4 |
| Campbell, S | 7 |
| Jauniaux, E | 1 |
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| Lechner, W | 1 |
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| Fleming, R | 1 |
| Jamieson, ME | 1 |
| Yates, RW | 1 |
| Coutts, JR | 1 |
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| Belfort, MA | 1 |
| Ottman, EH | 1 |
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| Downing, JW | 1 |
| Martinez, E | 2 |
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| Jiang, H | 1 |
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| DiFederico, EM | 2 |
| Harrison, M | 2 |
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| Bartels, U | 1 |
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| Vanderstichele, S | 3 |
| Ducloy, JC | 2 |
| Monnier, JC | 4 |
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| Bootstaylor, BS | 1 |
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| Dounas, M | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| GOT-IT Trial: A Pragmatic Group Sequential Placebo Controlled Randomised Trial to Determine the Effectiveness of Glyceryl Trinitrate for Retained Placenta.[NCT02085213] | Phase 4 | 1,107 participants (Actual) | Interventional | 2014-09-30 | Completed | ||
| The Relaxant Effect of Nitroglycerin on Oxytocin Desensitized Human Myometrium and the Return of Contractility on Re-exposure to Oxytocin- an in Vitro Study[NCT03408054] | 17 participants (Actual) | Interventional | 2018-01-03 | Completed | |||
| Acute Tocolysis With Terbutaline vs Placebo Prior to Emergency Caesarean Delivery for Suspected Intrauterine Fetal Compromise[NCT05326269] | 100 participants (Actual) | Interventional | 2017-04-23 | Completed | |||
| Use of Sildenafil Citrate in Management of Mild Pre-eclampsia: A Randomized Controlled Trial[NCT03262961] | Phase 2/Phase 3 | 80 participants (Anticipated) | Interventional | 2016-09-15 | Recruiting | ||
| Efficacy and Safety of L Arginine to Prevent Preeclampsia in High Risk Pregnancies[NCT02363348] | Phase 3 | 96 participants (Actual) | Interventional | 2010-08-31 | Completed | ||
| Effect of Sevoflurane on the Success of External Cephalic Version for Breech Presentation[NCT04346823] | Phase 4 | 40 participants (Anticipated) | Interventional | 2020-05-25 | Not yet recruiting | ||
| Spinal Anesthesia for External Cephalic Version in Nulliparous Women, A Controlled Randomized Study[NCT03797833] | 200 participants (Anticipated) | Interventional | 2019-01-07 | Suspended (stopped due to Slow inclusion rate. Central contact person quit for another job.) | |||
| Randomized Controlled Trial of IV Nitroglycerin in Cesarean Deliveries After Second Stage Arrest for the Prevention of Uterine Extension[NCT02265965] | Phase 4 | 18 participants (Actual) | Interventional | 2015-10-31 | Completed | ||
| Maternal Outcomes Following Manual Lysis of the Placenta After Fifteen Compared to Thirty Minutes. A Randomized Controlled Trial.[NCT03626844] | 100 participants (Anticipated) | Interventional | 2018-11-20 | Suspended (stopped due to Insufficient resources.) | |||
| INVERT: IV Nitroglycerin for Versions Trial - a Randomized Placebo-controlled Trial in Nulliparous Women[NCT00896311] | 82 participants (Actual) | Interventional | 2003-03-31 | Completed | |||
| Intravenous (IV) Nitroglycerin for Versions in Multiparous Women[NCT00901758] | 44 participants (Actual) | Interventional | 2003-03-31 | Completed | |||
| NITROGLYCERINE SKIN PATCH VS PLACEBO PATCH FOR ENHANCING CERVICAL RIPENING IN LABOR INDUCTION: A RANDOMIZED CONTROLLED TRIAL[NCT03320187] | Phase 2/Phase 3 | 100 participants (Actual) | Interventional | 2016-12-31 | Completed | ||
| Self-management of Postnatal Anti-hypertensive Treatment: a Trial Development Pilot Study[NCT02333240] | 101 participants (Actual) | Interventional | 2015-04-30 | Completed | |||
| Efficacy L-arginine + L-citrulline as a Dietary Supplement vs Placebo for Weight Gain in Fetus With a Decrease in Their Growth Curve in the Third Trimester of Pregnancy[NCT05029778] | Phase 4 | 41 participants (Anticipated) | Interventional | 2021-10-20 | Not yet recruiting | ||
| Exploratory Study. Endothelial Function and Vascular Biomarkers: Predictive Indicators of the Progression From Gestational Hypertension to Preeclampsia?[NCT04520048] | 110 participants (Anticipated) | Interventional | 2023-08-24 | Recruiting | |||
| Assessment of the Cardiovascular Risk Profile of Infants Exposed to Pre-eclampsia in Utero[NCT05091827] | 234 participants (Anticipated) | Observational | 2021-11-30 | Not yet recruiting | |||
| [NCT00005208] | 0 participants | Observational | 1987-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The APGAR scale is determined by evaluating the newborn baby on five simple criteria -- Appearance, Pulse, Grimace, Activity, Respiration -- on a scale from zero to two, then summing up the five values thus obtained. The resulting APGAR score ranges from zero to 10. Zero is the worst possible score and 10 is the highest possible score. (NCT02265965)
Timeframe: Immediately after cesarean delivery, estimated to be within 4 hours after diagnosis of second stage arrest
| Intervention | score on a scale (Median) |
|---|---|
| Intravenous Nitroglycerin | 9 |
| Intravenous Saline | 9 |
Time from uterine incision to delivery (body of neonate fully extracted from uterus) (NCT02265965)
Timeframe: At time of cesarean delivery, estimated to be within 4 hours after diagnosis of second stage arrest
| Intervention | seconds (Mean) |
|---|---|
| Intravenous Nitroglycerin | 104.9 |
| Intravenous Saline | 131 |
(NCT02265965)
Timeframe: After cesarean delivery, estimated to be within 4 hours after diagnosis of second stage arrest
| Intervention | Participants (Count of Participants) |
|---|---|
| Intravenous Nitroglycerin | 1 |
| Intravenous Saline | 2 |
A cord blood base deficit more negative than negative 12 is abnormal and a sign of metabolic acidosis. (NCT02265965)
Timeframe: At time of cesarean delivery, estimated to be within 4 hours after diagnosis of second stage arrest
| Intervention | Participants (Count of Participants) |
|---|---|
| Intravenous Nitroglycerin | 7 |
| Intravenous Saline | 11 |
Obstetrician determined whether the subject had an uterine extension. (NCT02265965)
Timeframe: During cesarean delivery, estimated to be within 4 hours after diagnosis of second stage arrest
| Intervention | Participants (Count of Participants) |
|---|---|
| Intravenous Nitroglycerin | 3 |
| Intravenous Saline | 4 |
Total blood loss will be measured (NCT02265965)
Timeframe: During and after cesarean delivery, estimated to be within 4 hours after diagnosis of second stage arrest
| Intervention | ml (Mean) |
|---|---|
| Intravenous Nitroglycerin | 935.7 |
| Intravenous Saline | 1036.4 |
Time from uterine incision to out of room (NCT02265965)
Timeframe: After cesarean delivery, estimated to be within 4 hours after diagnosis of second stage arrest
| Intervention | minutes (Mean) |
|---|---|
| Intravenous Nitroglycerin | 68.3 |
| Intravenous Saline | 74.2 |
Measure of umbilical artery blood pH (NCT02265965)
Timeframe: At time of cesarean delivery, estimated to be within 4 hours after diagnosis of second stage arrest
| Intervention | pH (Mean) |
|---|---|
| Intravenous Nitroglycerin | 7.3 |
| Intravenous Saline | 7.3 |
27 reviews available for nitroglycerin and Pregnancy
| Article | Year |
|---|---|
Interventions affecting the nitric oxide pathway versus placebo or no therapy for fetal growth restriction in pregnancy.
Topics: Female; Fetal Death; Fetal Growth Retardation; Humans; Infant, Newborn; Nitric Oxide; Nitroglycerin; | 2023 |
Use of nitroglycerin for parallel transverse uterine cesarean section in patients with pernicious placenta previa and placenta accrete and predicted difficult airway: A case report and review of literature.
Topics: Administration, Intravenous; Adult; Cesarean Section; Female; Humans; Nitroglycerin; Placenta Accret | 2020 |
Acute tocolysis for uterine tachysystole or suspected fetal distress.
Topics: Adrenergic beta-2 Receptor Agonists; Cesarean Section; Female; Fenoterol; Fetal Distress; Hexoprenal | 2018 |
Transdermal nitroglycerin for the treatment of preterm labor: a systematic review and metaanalysis.
Topics: Administration, Cutaneous; Adrenergic beta-2 Receptor Agonists; Female; Humans; Magnesium Sulfate; N | 2013 |
Severe pre-eclampsia and hypertensive crises.
Topics: Administration, Intravenous; Administration, Oral; Antihypertensive Agents; Critical Care; Early Dia | 2013 |
The nitric oxide pathway and possible therapeutic options in pre-eclampsia.
Topics: Aldehyde Oxidoreductases; Clinical Trials as Topic; Endothelium, Vascular; Female; Humans; Isosorbid | 2014 |
Nitric oxide donors for treating preterm labour.
Topics: Female; Humans; Nitric Oxide Donors; Nitroglycerin; Obstetric Labor, Premature; Pregnancy; Randomize | 2014 |
What is the optimal pharmacological management of retained placenta?
Topics: Drug Administration Routes; Drug Therapy, Combination; Female; Humans; Nitroglycerin; Oxytocics; Oxy | 2014 |
Interventions for helping to turn term breech babies to head first presentation when using external cephalic version.
Topics: Analgesia, Obstetrical; Breech Presentation; Calcium Channel Blockers; Delivery, Obstetric; Female; | 2015 |
Interventions for helping to turn term breech babies to head first presentation when using external cephalic version.
Topics: Analgesia, Obstetrical; Breech Presentation; Calcium Channel Blockers; Delivery, Obstetric; Female; | 2015 |
Interventions for helping to turn term breech babies to head first presentation when using external cephalic version.
Topics: Analgesia, Obstetrical; Breech Presentation; Calcium Channel Blockers; Delivery, Obstetric; Female; | 2015 |
Interventions for helping to turn term breech babies to head first presentation when using external cephalic version.
Topics: Analgesia, Obstetrical; Breech Presentation; Calcium Channel Blockers; Delivery, Obstetric; Female; | 2015 |
Nitroglycerin for management of retained placenta.
Topics: Administration, Sublingual; Female; Headache; Humans; Nitroglycerin; Oxytocics; Oxytocin; Placenta, | 2015 |
Tocolysis for management of retained placenta.
Topics: Administration, Sublingual; Female; Humans; Nitroglycerin; Oxytocics; Oxytocin; Placenta, Retained; | 2011 |
Interventions for helping to turn term breech babies to head first presentation when using external cephalic version.
Topics: Analgesia, Obstetrical; Breech Presentation; Calcium Channel Blockers; Delivery, Obstetric; Female; | 2012 |
Nitric oxide donors for the treatment of preterm labour.
Topics: Female; Humans; Nitric Oxide Donors; Nitroglycerin; Obstetric Labor, Premature; Pregnancy; Randomize | 2002 |
Nitroglycerin as a uterine relaxant: a systematic review.
Topics: Cesarean Section; Dysmenorrhea; Embryo Transfer; Female; Humans; Nitroglycerin; Obstetric Labor, Pre | 2002 |
Recent pharmacological advances in the treatment of preterm membrane rupture, labour and delivery.
Topics: Adrenergic beta-2 Receptor Agonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; | 2004 |
Acute tocolysis.
Topics: Emergency Medical Services; Female; Humans; Labor, Obstetric; Nitroglycerin; Pregnancy; Time Factors | 2005 |
Nitric oxide for preventing pre-eclampsia and its complications.
Topics: Female; Humans; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Pre-Eclampsia; Pregnancy; Randomiz | 2007 |
Acute tocolysis for uterine activity reduction in term labor: a review.
Topics: Adrenergic beta-Agonists; Female; Humans; Labor, Obstetric; Nitric Oxide; Nitroglycerin; Pregnancy; | 2008 |
Intravenous glyceryl trinitrate (nitroglycerin). A review of its pharmacological properties and therapeutic efficacy.
Topics: Acute Disease; Administration, Oral; Administration, Topical; Angina, Unstable; Animals; Cardiac Sur | 1984 |
Current pharmacology and the obstetric anesthesiologist.
Topics: Anesthesia, Obstetrical; Calcium Channel Blockers; Female; Humans; Magnesium Sulfate; Nitroglycerin; | 1994 |
Intrapartum management of multiple gestations.
Topics: Birth Weight; Cesarean Section; Delivery, Obstetric; Female; Gestational Age; Humans; Infant Care; I | 1996 |
The use of intravenous nitroglycerin for cervico-uterine relaxation: a review of the literature.
Topics: Breech Presentation; Cervix Uteri; Cesarean Section; Female; Humans; Infusions, Intravenous; Muscle | 1997 |
Cervical ripening after nitric oxide.
Topics: Animals; Cervix Uteri; Female; Humans; Isosorbide Dinitrate; Labor Stage, First; Nitric Oxide; Nitro | 1998 |
Clinical pharmacokinetics of vasodilators. Part II.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Alprostadil; Amrinone; Carbazoles; Carvedilo | 1998 |
Use of nitroglycerin for uterine relaxation.
Topics: Animals; Dose-Response Relationship, Drug; Female; Humans; Nitric Oxide Donors; Nitroglycerin; Place | 1998 |
Glyceryl trinitrate and acute uterine relaxation: a literature review.
Topics: Animals; Cyclic GMP; Female; Hemodynamics; Humans; Muscle Relaxation; Nitric Oxide; Nitroglycerin; O | 2001 |
[Management of peroperative hypertensive crises].
Topics: Adrenergic beta-Antagonists; Anesthesia, General; Calcium Channel Blockers; Clonidine; Coronary Dise | 1988 |
53 trials available for nitroglycerin and Pregnancy
| Article | Year |
|---|---|
Subcutaneous nitroglycerin increased the success rate of radial artery cannulation in women with gestational hypertension undergoing cesarean section : A randomized controlled trial.
Topics: Catheterization, Peripheral; Cesarean Section; Child; Female; Humans; Hypertension, Pregnancy-Induce | 2023 |
Nitroglycerin for treatment of retained placenta: A randomised, placebo-controlled, multicentre, double-blind trial in the UK.
Topics: Administration, Sublingual; Adult; Cost-Benefit Analysis; Delivery, Obstetric; Double-Blind Method; | 2019 |
Glyceryl trinitrate to reduce the need for manual removal of retained placenta following vaginal delivery: the GOT-IT RCT.
Topics: Administration, Sublingual; Adolescent; Adult; Blood Transfusion; Cost-Benefit Analysis; Double-Blin | 2019 |
The Effects of Nitroglycerin on the Oxytocin Dose-Response Profile in Oxytocin-Desensitized and Naïve Human Myometrium: An In Vitro Study.
Topics: Adult; Cesarean Section; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Myomet | 2021 |
A pragmatic group sequential, placebo-controlled, randomised trial to determine the effectiveness of glyceryl trinitrate for retained placenta (GOT-IT): a study protocol.
Topics: Administration, Sublingual; Blood Volume; Cost Savings; Cost-Benefit Analysis; Double-Blind Method; | 2017 |
Comparison between nitroglycerin dermal patch and nifedipine for treatment of preterm labor: a randomized clinical trial.
Topics: Apgar Score; Birth Weight; Cesarean Section; Female; Gestational Age; Humans; Infant, Newborn; Inten | 2014 |
Comparison between transdermal nitroglycerin and sildenafil citrate in intrauterine growth restriction: effects on uterine, umbilical and fetal middle cerebral artery pulsatility indices.
Topics: Administration, Cutaneous; Adult; Blood Flow Velocity; Double-Blind Method; Female; Fetal Growth Ret | 2016 |
The effects of sequential use of oxytocin and sublingual nitroglycerin in the cases of retained placenta.
Topics: Administration, Sublingual; Adult; Female; Humans; Nitroglycerin; Oxytocics; Oxytocin; Placenta, Ret | 2016 |
Intravenous nitroglycerin for external cephalic version: a randomized controlled trial.
Topics: Adult; Breech Presentation; Cesarean Section; Dose-Response Relationship, Drug; Double-Blind Method; | 2009 |
Intravenous nitroglycerin for external cephalic version: a randomized controlled trial.
Topics: Adult; Breech Presentation; Cesarean Section; Dose-Response Relationship, Drug; Double-Blind Method; | 2009 |
Intravenous nitroglycerin for external cephalic version: a randomized controlled trial.
Topics: Adult; Breech Presentation; Cesarean Section; Dose-Response Relationship, Drug; Double-Blind Method; | 2009 |
Intravenous nitroglycerin for external cephalic version: a randomized controlled trial.
Topics: Adult; Breech Presentation; Cesarean Section; Dose-Response Relationship, Drug; Double-Blind Method; | 2009 |
[Transdermal nitroglycerin versus oral nifedipine administration for tocolysis: a randomized clinical trial].
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Female; Humans; Nifedipine; Nitr | 2009 |
Secondary analysis of the use of transdermal nitroglycerin for preterm labor.
Topics: Administration, Cutaneous; Adult; Confidence Intervals; Delivery, Obstetric; Dose-Response Relations | 2010 |
Intravenous nitroglycerin for controlled cord traction in the management of retained placenta.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Injections, Intravenous; Nitroglycerin; Placenta, | 2011 |
Effects of sublingual nitroglycerin on human uterine contractility during the active phase of labor.
Topics: Administration, Sublingual; Adult; Double-Blind Method; Female; Humans; Labor, Obstetric; Multivaria | 2002 |
Maternal nitric oxide supplementation increases adrenomedullin concentrations in growth retarded fetuses.
Topics: Administration, Cutaneous; Adrenomedullin; Adult; Double-Blind Method; Female; Fetal Growth Retardat | 2002 |
Nitric oxide donors for patients undergoing IVF. A prospective, double-blind, randomized, placebo-controlled trial.
Topics: Administration, Cutaneous; Double-Blind Method; Embryo Implantation; Embryo Transfer; Endometrium; F | 2002 |
Maternal and fetal side effects of tocolysis using transdermal nitroglycerin or intravenous fenoterol combined with magnesium sulfate.
Topics: Administration, Cutaneous; Adolescent; Adult; Blood Pressure; Drug Therapy, Combination; Female; Fen | 2003 |
Sublingual nitroglycerin versus intravenous ritodrine as tocolytic for external cephalic version: a double-blinded randomized trial.
Topics: Administration, Sublingual; Adult; Double-Blind Method; Female; Humans; Infusions, Intravenous; Nitr | 2003 |
Second-trimester pregnancy termination: comparison of three different methods.
Topics: Abortifacient Agents; Abortion, Induced; Administration, Intravaginal; Adult; Analgesia; Contraindic | 2003 |
NO-donor nitroglycerin versus the prostaglandin gemeprost for cervical ripening in first trimester missed abortion.
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Missed; Administration, Intravaginal; Adult; Alprostad | 2003 |
Sublingual nitroglycerin versus placebo as a tocolytic for external cephalic version: a randomized controlled trial in parous women.
Topics: Administration, Sublingual; Adult; Double-Blind Method; Female; Headache; Humans; Nitroglycerin; Par | 2003 |
Tocolytic effects of intravenous nitroglycerin.
Topics: Adult; Clinical Protocols; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fetal Bloo | 2004 |
Glyceryl trinitrate vs. ritodrine for the treatment of preterm labor.
Topics: Administration, Cutaneous; Female; Humans; Infusions, Intravenous; Nitroglycerin; Obstetric Labor, P | 2004 |
[Effect of long-term therapy with transdermal patches releasing glyceryl trinitrate (GTN) used in pregnant hypertensive women on stabilisation of blood pressure and on the condition of the newborn infant].
Topics: Administration, Cutaneous; Adult; Blood Pressure; Dose-Response Relationship, Drug; Drug Administrat | 2004 |
The effect of glyceryl trinitrate on hypertension in women with severe preeclampsia, HELLP syndrome, and eclampsia.
Topics: Adult; Aspartate Aminotransferases; Bilirubin; Biomarkers; Blood Platelets; Blood Pressure; Diastole | 2004 |
The Randomized Nitric Oxide Tocolysis Trial (RNOTT) for the treatment of preterm labor.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adult; Delivery, Obstetric; Female; G | 2004 |
Randomized comparison of intravenous nitroglycerin and subcutaneous terbutaline for external cephalic version under tocolysis.
Topics: Female; Follow-Up Studies; Gestational Age; Humans; Infusions, Intravenous; Injections, Subcutaneous | 2004 |
Evaluation of glyceryl trinitrate, misoprostol, and prostaglandin E2 gel for preinduction cervical ripening in term pregnancy.
Topics: Administration, Intravaginal; Cervical Ripening; Dinoprostone; Female; Gels; Humans; Labor Onset; Mi | 2005 |
Sublingual nitroglycerin for management of retained placenta.
Topics: Administration, Sublingual; Adult; Blood Pressure; Delivery, Obstetric; Double-Blind Method; Female; | 2005 |
Intravaginal glyceryl trinitrate and dinoprostone for cervical ripening and induction of labor.
Topics: Administration, Intravaginal; Adult; Cervical Ripening; Dinoprostone; Double-Blind Method; Female; H | 2006 |
Neonatal neurodevelopmental outcomes following tocolysis with glycerol trinitrate patches.
Topics: Adrenergic beta-Agonists; Albuterol; Child Development; Female; Humans; Infant; Intelligence; Nitrog | 2006 |
Randomized double-blind placebo-controlled trial of transdermal nitroglycerin for preterm labor.
Topics: Administration, Cutaneous; Adult; Double-Blind Method; Female; Humans; Infant, Newborn; Infant, Newb | 2007 |
Randomized comparison of intravenous terbutaline vs nitroglycerin for acute intrapartum fetal resuscitation.
Topics: Adult; Blood Pressure; Female; Fetal Distress; Fetus; Heart Rate, Fetal; Humans; Infant, Newborn; Ni | 2007 |
Efficacy of nitroglycerine infusion versus sublingual nifedipine in severe pre-eclampsia: a randomized, triple-blind, controlled trial.
Topics: Administration, Sublingual; Adult; Female; Humans; Injections, Intravenous; Magnesium Sulfate; Nifed | 2008 |
Sublingual nitroglycerin seems to be effective in the management of retained placenta.
Topics: Administration, Sublingual; Adult; Drug Therapy, Combination; Female; Humans; Injections, Intramuscu | 2008 |
Intravenous glyceryl trinitrate (nitroglycerin). A review of its pharmacological properties and therapeutic efficacy.
Topics: Acute Disease; Administration, Oral; Administration, Topical; Angina, Unstable; Animals; Cardiac Sur | 1984 |
A nitric oxide donor improves uterine artery diastolic blood flow in normal early pregnancy and in women at high risk of pre-eclampsia.
Topics: Adaptation, Physiological; Blood Flow Velocity; Diastole; Epoprostenol; Female; Humans; Infusions, I | 1994 |
Assessments of embryo transfer after in-vitro fertilization: effects of glyceryl trinitrate.
Topics: Cervix Uteri; Double-Blind Method; Embryo Transfer; Female; Fertilization in Vitro; Humans; Muscle R | 1993 |
[Nitric oxide: its role in the development of pregnancy complications and in their prevention in women with hypertension and chronic glomerulonephritis].
Topics: Administration, Cutaneous; Adult; Chronic Disease; Female; Glomerulonephritis; Humans; Hypertension; | 1997 |
Nitroglycerin to facilitate fetal extraction during cesarean delivery.
Topics: Adult; Cesarean Section; Cohort Studies; Dose-Response Relationship, Drug; Double-Blind Method; Extr | 1998 |
Corticotropin-releasing hormone: a biochemical predictor of preterm delivery in a pilot randomized trial of the treatment of preterm labor.
Topics: Administration, Cutaneous; Adult; Albuterol; Corticotropin-Releasing Hormone; Female; Gestational Ag | 1998 |
Intravenous nitroglycerin for internal podalic version of the second twin in transverse lie.
Topics: Adult; Female; Humans; Injections, Intravenous; Nitroglycerin; Parasympatholytics; Pregnancy; Twins; | 1998 |
The efficacy and fetal-maternal cardiovascular effects of transdermal glyceryl trinitrate in the prophylaxis of pre-eclampsia and its complications: a randomized double-blind placebo-controlled trial.
Topics: Administration, Cutaneous; Adult; Arteries; Cardiovascular System; Double-Blind Method; Female; Hemo | 1998 |
Randomized comparison of intravenous nitroglycerin and magnesium sulfate for treatment of preterm labor.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Injections, Intravenous; Magnesium Sulfate; Nitro | 1999 |
Randomised, double-blind, placebo controlled pilot study assessing nitroglycerin as a tocolytic.
Topics: Administration, Cutaneous; Adult; Double-Blind Method; Female; Humans; Nitroglycerin; Obstetric Labo | 1999 |
24-hour ambulatory blood pressure monitoring: a comparison between transdermal glyceryl-trinitrate and oral nifedipine.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Analysis of Variance; Female; Humans; Hypert | 1999 |
Glyceryl trinitrate and ritodrine in tocolysis: an international multicenter randomized study. GTN Preterm Labour Investigation Group.
Topics: Adolescent; Adult; Female; Humans; Nitroglycerin; Obstetric Labor, Premature; Pregnancy; Ritodrine; | 1999 |
Maternal and fetal cardiovascular effects of transdermal glyceryl trinitrate and intravenous ritodrine.
Topics: Administration, Cutaneous; Adult; Cardiovascular System; Female; Fetus; Humans; Injections, Intraven | 1999 |
Double-blind randomised controlled trial of glyceryl trinitrate spray for external cephalic version.
Topics: Administration, Intravaginal; Adult; Breech Presentation; Double-Blind Method; Female; Humans; Nitro | 2000 |
Randomized comparison of glyceryl trinitrate and prostaglandin E2 for cervical ripening at term.
Topics: Adult; Cervical Ripening; Cesarean Section; Dinoprostone; Female; Humans; Labor, Induced; Nitric Oxi | 2000 |
Potential efficacy of nitric oxide for cervical ripening in pregnancy at term.
Topics: Cervical Ripening; Dinoprostone; Female; Humans; Isosorbide Dinitrate; Nitric Oxide Donors; Nitrogly | 2000 |
Oxytocics reverse the tocolytic effect of glyceryl trinitrate on the human uterus.
Topics: Dinoprost; Ergonovine; Female; Humans; Myometrium; Nitroglycerin; Oxytocics; Oxytocin; Pregnancy; Ut | 2001 |
Nitric oxide for treatment of threatened preterm labor.
Topics: Administration, Cutaneous; Cardiotocography; Drug Monitoring; Female; Gestational Age; Humans; Nitri | 2001 |
[Clinical effect and mechanism of nitroglycerin patch on arresting preterm labor].
Topics: Adult; Albuterol; Corticotropin-Releasing Hormone; Drug Therapy, Combination; Female; Humans; Magnes | 2002 |
199 other studies available for nitroglycerin and Pregnancy
| Article | Year |
|---|---|
Hyperhomocysteinemia Increases Cortical Excitability and Aggravates Mechanical Hyperalgesia and Anxiety in a Nitroglycerine-Induced Migraine Model in Rats.
Topics: Animals; Anxiety; Cortical Excitability; Female; Homocysteine; Hyperalgesia; Hyperhomocysteinemia; M | 2022 |
Pharmacological strategies to prevent haemodynamic changes after intubation in parturient women with hypertensive disorders of pregnancy: A network meta-analysis.
Topics: Anesthesia, General; Antihypertensive Agents; Apgar Score; Blood Pressure; Blood Pressure Determinat | 2021 |
The Successful Use of Nitroglycerin for Uterine Hyperstimulation with Fetal Heart Rate Abnormality Caused by a Controlled-Release Dinoprostone Vaginal Delivery System (PROPESS): A Case Report.
Topics: Cesarean Section; Delayed-Action Preparations; Dinoprostone; Female; Heart Rate, Fetal; Humans; Labo | 2021 |
Inflammation-induced fetal growth restriction in rats is associated with increased placental HIF-1α accumulation.
Topics: Animals; Disease Models, Animal; Female; Fetal Growth Retardation; Gene Expression Regulation; Gesta | 2017 |
Differential responses of mesenteric arterial bed to vasoactive substances in L-NAME-induced preeclampsia: Role of oxidative stress and endothelial dysfunction.
Topics: Acetylcholine; Angiotensin II; Animals; Arginine; Blood Pressure; Enzyme Inhibitors; Female; Fetal G | 2018 |
Intravenous anesthesia with nitroglycerin inhalation for surgical abortion in a patient with severe congenital heart disease and low oxygen saturation: A case report.
Topics: Abortion, Induced; Adult; Anesthesia, Intravenous; Blood Gas Analysis; Blood Pressure Determination; | 2018 |
Multimodal general anesthesia approach for Ex Utero Intrapartum Therapy (EXIT) procedures: two case reports.
Topics: Adult; Analgesics, Opioid; Anesthesia, General; Anesthesia, Obstetrical; Craniofacial Abnormalities; | 2019 |
In Utero Exposure to Alcohol Impairs Reactivity of Cerebral Arterioles and Increases Susceptibility of the Brain to Damage Following Ischemia/Reperfusion in Adulthood.
Topics: Acetophenones; Adenosine Diphosphate; Animals; Arterioles; Brain; Enzyme Inhibitors; Ethanol; Excita | 2019 |
Comparison of Nitroglycerin and Terbutaline for External Cephalic Version in Women Who Received Neuraxial Anesthesia: A Retrospective Analysis.
Topics: Anesthesia, Obstetrical; Breech Presentation; Cesarean Section; Female; Humans; Live Birth; Nitrogly | 2020 |
Effect of nitric oxide on physical development and erythropoiesis in the offspring of rats with impaired uteroplacental circulation.
Topics: Animals; Animals, Outbred Strains; Body Weight; Erythropoiesis; Female; Fetal Hypoxia; Nitric Oxide | 2013 |
[The effect of nitroglycerin 200 microg on uterine relaxation during cesarean delivery].
Topics: Cesarean Section; Female; Humans; Injections, Intravenous; Nitroglycerin; Pregnancy; Uterine Contrac | 2013 |
A novel treatment for management of a trapped placenta using intracervical nitroglycerin tablets.
Topics: Administration, Intravaginal; Adult; Female; Humans; Nitroglycerin; Placenta, Retained; Pregnancy; T | 2013 |
Use of intra-arterial nitroglycerin during uterine artery embolization for severe postpartum hemorrhage with uterine artery vasospasm.
Topics: Adult; Cesarean Section; Combined Modality Therapy; Constriction, Pathologic; Female; Humans; Nitrog | 2015 |
Nanoliposomal Nitroglycerin Exerts Potent Anti-Inflammatory Effects.
Topics: Animals; Anti-Inflammatory Agents; Cell Adhesion; Cell Line; Dose-Response Relationship, Drug; Endot | 2015 |
Fetal growth is associated with first-trimester maternal vascular function.
Topics: Adult; Birth Weight; Brachial Artery; Cross-Sectional Studies; Female; Fetal Development; Forearm; H | 2016 |
The association between nitroglycerin use and adverse outcomes in women undergoing cesarean delivery in the second stage of labor.
Topics: Administration, Intravenous; Administration, Sublingual; Adult; Cesarean Section; Female; Humans; La | 2017 |
Neglected shoulder presentation with foetal death managed by internal podalic version with nitroglycerine and sevoflurane.
Topics: Abruptio Placentae; Adult; Anesthetics, Inhalation; Female; Fetal Death; Humans; Labor Presentation; | 2017 |
Neurally Mediated Syncope During Cesarean Delivery: A Case Report.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Bradycardia; Cardiopulmonary Resuscitation; Cesa | 2017 |
Uterine relaxation during caesarean section under regional anaesthesia: a survey of UK obstetric anaesthetists.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Cesarean Section; Female; Humans; Muscle Relaxation | 2008 |
The retained placenta.
Topics: Female; Humans; Labor Stage, Third; Nitroglycerin; Oxytocics; Oxytocin; Placenta, Retained; Pregnanc | 2008 |
[Use of nitroglycerin to facilitate obstetric analgesia].
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Female; Humans; Infant, Newborn; Labor, Induced; | 2008 |
Intravenous nitroglycerin: a potent uterine relaxant for internal podalic version: case.
Topics: Adult; Analgesics; Delivery, Obstetric; Female; Humans; Infant, Newborn; Injections, Intravenous; Ke | 2009 |
Parallel decrease in arterial distensibility and in endothelium-dependent dilatation in young women with a history of pre-eclampsia.
Topics: Adolescent; Adult; Birth Weight; Blood Flow Velocity; Carotid Arteries; Case-Control Studies; Cross- | 2009 |
[Hypertensive urgency or hypertensive emergency?].
Topics: Adult; Antihypertensive Agents; Blood Pressure Determination; Emergencies; Female; Follow-Up Studies | 2010 |
Maternal transdermal nitroglycerin use and early childhood development.
Topics: Administration, Cutaneous; Canada; Child Development; Child, Preschool; Female; Follow-Up Studies; H | 2010 |
Transdermal nitroglycerin in patients with severe pre-eclampsia with placental insufficiency: effect on uterine, umbilical and fetal middle cerebral artery resistance indices.
Topics: Adult; Blood Flow Velocity; Female; Gestational Age; Humans; Middle Cerebral Artery; Nitroglycerin; | 2011 |
Remifentanil-nitroglycerin combination as an anesthetic support for ex utero intrapartum treatment (EXIT) procedure.
Topics: Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, General; Drug Therapy, Combination; Femal | 2011 |
Glyceryl trinitrate inhibits hypoxia-induced release of soluble fms-like tyrosine kinase-1 and endoglin from placental tissues.
Topics: Antigens, CD; Chorionic Villi; Endoglin; Female; Gene Expression Regulation; Gene Knockdown Techniqu | 2011 |
Pre-eclampsia: a maternal manifestation of a fetal adaptive response?
Topics: Blood Flow Velocity; Female; Humans; Middle Cerebral Artery; Nitroglycerin; Placental Insufficiency; | 2011 |
Nitroglycerin prevents coagulopathies and foetal death associated with abnormal maternal inflammation in rats.
Topics: Administration, Cutaneous; Animals; Blood Coagulation; Blood Coagulation Disorders; Etanercept; Fema | 2012 |
Efficacy of transdermal nitroglycerine in idiopathic pre-term labour.
Topics: Administration, Cutaneous; Adult; Female; Gestational Age; Humans; Infant, Newborn; Male; Nitroglyce | 2012 |
[The role of nitric oxide in regulation of the erythrocyte system state in rat offspring with chronic disturbance of uteroplacental blood circulation].
Topics: Animals; Animals, Newborn; Erythrocytes; Erythropoiesis; Female; Fetal Hypoxia; Male; Nitric Oxide; | 2012 |
Successful management of aortic dissection in a patient with Marfan syndrome during pregnancy.
Topics: Adult; Aortic Aneurysm; Aortic Dissection; Blood Pressure; Calcium Channel Blockers; Coronary Angiog | 2013 |
Uterine tocolysis at cesarean breech delivery with epidural anesthesia.
Topics: Adult; Anesthesia, Epidural; Apgar Score; Breech Presentation; Cesarean Section; Female; Humans; Med | 2002 |
[Role of nitric oxide in pathogenesis of pregnancy induced hypertension].
Topics: Animals; Endothelin-1; Female; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nit | 2000 |
[The use of nitroglycerin as nitric oxide donor for treatment of preterm labour].
Topics: Administration, Cutaneous; Adult; Female; Humans; Hypertension; Nitric Oxide Donors; Nitroglycerin; | 2002 |
The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Dopamine; Dose-Response Relation | 2003 |
Nitroglycerin for fetal surgery: fetoscopy and ex utero intrapartum treatment procedure with malignant hyperthermia precautions.
Topics: Adult; Constriction; Female; Fetoscopy; Fetus; Hernia, Diaphragmatic; Humans; Hysterotomy; Infant, N | 2003 |
[The influence of transdermal nitroglycerin patches on fetal blood flow parameters in threatened preterm labor].
Topics: Administration, Cutaneous; Adult; Blood Flow Velocity; Female; Fetus; Humans; Nitroglycerin; Obstetr | 2002 |
Sublingual nitroglycerine as a tocolytic in external cephalic version: a comparative study.
Topics: Administration, Sublingual; Adolescent; Adult; Breech Presentation; Case-Control Studies; Delivery, | 2003 |
Nitric oxide metabolites in cervical fluid during pregnancy: further evidence for the role of cervical nitric oxide in cervical ripening.
Topics: Administration, Topical; Adult; Body Fluids; Cervical Ripening; Cervix Uteri; Female; Humans; Labor, | 2003 |
Cardiovascular regulation and expressions of NO synthase-tyrosine hydroxylase in nucleus tractus solitarius of ovine fetus.
Topics: Animals; Animals, Newborn; Blood Pressure; Cardiovascular System; Delivery, Obstetric; Enzyme Inhibi | 2003 |
Intravenous nitro-glycerine versus general anaesthesia for placental extraction--a sequential comparison.
Topics: Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Female; Fentanyl; Hemodynami | 2003 |
Intravenous nitroglycerin in the management of retained placenta.
Topics: Adult; Blood Pressure; Female; Humans; Nitroglycerin; Placenta, Retained; Pregnancy; Pulse | 2003 |
Nitroglycerin-aggravated pre-eclamptic posterior reversible encephalopathy syndrome (PRES).
Topics: Adult; Brain; Brain Diseases; Female; Humans; Magnetic Resonance Imaging; Nitroglycerin; Pre-Eclamps | 2003 |
The nitroglycerin flicker fusion threshold test in toxemia of pregnancy.
Topics: Female; Flicker Fusion; Nitroglycerin; Pre-Eclampsia; Pregnancy; Vision, Ocular | 1952 |
The significance of the nitroglycerine flicker fusion response in normal subjects and in pregnancy.
Topics: Female; Flicker Fusion; Humans; Nitroglycerin; Pre-Eclampsia; Pregnancy; Vision, Ocular | 1953 |
Flicker fusion threshold; nitroglycerine response as a screening test for toxemia of pregnancy.
Topics: Female; Flicker Fusion; Nitrites; Nitroglycerin; Pre-Eclampsia; Pregnancy; Vision, Ocular | 1954 |
A statistical evaluation of the nitroglycerine flicker-fusion threshold test and the weight-gain sign in the prediction of the clinical syndrome of pre-eclampsia.
Topics: Body Weight; Female; Humans; Nitroglycerin; Pre-Eclampsia; Pregnancy; Vision Tests; Vision, Ocular; | 1957 |
EFFECT OF CERTAIN DRUGS ON PERFUSED HUMAN PLACENTAS. II. VASODILATORS.
Topics: Female; Humans; Isoproterenol; Nitroglycerin; Papaverine; Perfusion; Pharmacology; Placenta; Pregnan | 1963 |
CONGENITAL LEUKEMIA.
Topics: Antifungal Agents; Communicable Diseases; Dextropropoxyphene; Female; Humans; Infant, Newborn; Infan | 1964 |
Effects of nitric oxide donors on non-pregnant and pregnant rat uterine and aortic smooth muscle.
Topics: Animals; Aorta; Dose-Response Relationship, Drug; Female; Hydrazines; In Vitro Techniques; Muscle, S | 2003 |
Steady-state maternal and fetal plasma concentrations of glyceryl trinitrate (GTN) in the preterm sheep.
Topics: Administration, Cutaneous; Animals; Blood Gas Monitoring, Transcutaneous; Blood Pressure; Chromatogr | 2003 |
Human maternal and fetal plasma glyceryl trinitrate concentrations.
Topics: Administration, Cutaneous; Biological Availability; Female; Fetal Blood; Gestational Age; Humans; Ma | 2003 |
Nitroglycerin for relaxation to establish a fetal airway (EXIT procedure).
Topics: Adolescent; Airway Obstruction; Anesthesia, Obstetrical; Delivery, Obstetric; Female; Fetal Diseases | 2004 |
Contractile properties of human placental anchoring villi.
Topics: Chorionic Villi; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; In Vitro Techn | 2004 |
Nitric oxide donors: effects on fetoplacental blood flow.
Topics: Arteries; Female; Fetus; Gestational Age; Humans; Nitric Oxide Donors; Nitroglycerin; Obstetric Labo | 2004 |
Four cases of the ex utero intrapartum treatment (EXIT) procedure: anesthetic implications.
Topics: Adult; Airway Obstruction; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthetics, Inhalation; | 2004 |
Drug labelling and a near miss in the labour suite.
Topics: Adult; Canada; Cesarean Section; Delivery Rooms; Dose-Response Relationship, Drug; Drug Labeling; Em | 2004 |
Acute coronary syndrome induced by intravenous ephedrine in pregnant woman with normal coronaries.
Topics: Acute Disease; Adult; Anesthesia, Obstetrical; Cesarean Section; Coronary Angiography; Coronary Dise | 2004 |
Nitroglycerin to facilitate insertion of a labor epidural.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Female; Humans; Nitroglycerin; Pregnancy; Vasodi | 2005 |
[Nitroglycerin to relax the uterus during cesarean delivery for the low birthweight baby].
Topics: Anesthesia, General; Anesthesia, Obstetrical; Cesarean Section; Female; Humans; Infant, Low Birth We | 2005 |
Clinical problem-solving. Double jeopardy.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Aortic Dissection; Cardiac Catheterization; Chest P | 2005 |
Cardiovascular risk factors in healthy women with previous gestational hypertension.
Topics: Adult; Blood Glucose; Body Composition; Brachial Artery; Carbohydrate Metabolism; Cardiovascular Dis | 2006 |
Nitric oxide donor-induced inhibition of pregnant rat uterine spontaneous contractile activity and release of nitric oxide from uterus measured by microdialysis.
Topics: Animals; Chromatography, High Pressure Liquid; Diethylamines; Female; Microdialysis; Myometrium; Nit | 2005 |
Resolution of peripheral tissue ischemia secondary to arterial vasospasm following treatment with a topical nitroglycerin device in two newborns: case reports.
Topics: Administration, Topical; Arteries; Blood Gas Analysis; Catheterization, Peripheral; Female; Humans; | 2006 |
Nitroglycerin for uterine inversion in the absence of placental fragments.
Topics: Adult; Female; Humans; Nitroglycerin; Placenta; Pregnancy; Uterine Inversion | 2006 |
Transdermal nitroglycerin for preterm labor.
Topics: Administration, Cutaneous; Female; Humans; Nitroglycerin; Obstetric Labor, Premature; Pregnancy; Toc | 2007 |
Cardiorespiratory symptoms in pregnancy: not always pulmonary embolism.
Topics: Cardiomyopathies; Cesarean Section; Chest Pain; Diagnosis, Differential; Diuretics; Dyspnea; Echocar | 2007 |
Glyceryl trinitrate inhibits hypoxia/reoxygenation-induced apoptosis in the syncytiotrophoblast of the human placenta: therapeutic implications for preeclampsia.
Topics: Aldehydes; Apoptosis; Blotting, Western; Caspase 3; Collagen Type XI; Female; Humans; Hypoxia; Immun | 2007 |
Case series: Combined spinal epidural anesthesia for Cesarean delivery and ex utero intrapartum treatment procedure.
Topics: Adult; Airway Obstruction; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Bupiva | 2007 |
Ex utero intrapartum treatment procedure in a patient with arthrogryposis multiplex congenita, using continuous spinal anesthesia and intravenous nitroglycerin for uterine relaxation.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Arthrogryposis; Cesarean S | 2008 |
The use of potent inhalational agents for the ex- utero intrapartum treatment (exit) procedures: what concentrations?
Topics: Adult; Anesthesia; Anesthetics, Inhalation; Cesarean Section; Electrocardiography; Female; Fetus; Hu | 2007 |
Randomized, double-blind, placebo-controlled trial of transdermal nitroglycerin for preterm labor.
Topics: Administration, Cutaneous; Double-Blind Method; Female; Gestational Age; Humans; Nitroglycerin; Obst | 2007 |
Effects of nitroglycerin and nitroprusside on the uterine vasculature of gravid ewes.
Topics: Animals; Blood Pressure; Female; Ferricyanides; Hypertension; Nitroglycerin; Nitroprusside; Norepine | 1980 |
Nitroglycerin therapy for phenylephrine-induced hypertension in pregnant ewes.
Topics: Animals; Female; Gestational Age; Hemodynamics; Hypertension; Nitroglycerin; Phenylephrine; Pregnanc | 1980 |
Glyceryl trinitrate ointment 2 percent: drugs in current use.
Topics: Female; Humans; Nitroglycerin; Ointments; Pregnancy | 1980 |
[Clinical use of nitroglycerin as an hypotensive agent during general anesthesia for caesarean section. Report of a case (author's transl)].
Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Cesarean Section; Female; Humans; Hypertension; | 1980 |
Plasma levels and cardiovascular effect of nitroglycerin in pregnant sheep.
Topics: Animals; Blood Pressure; Cardiovascular System; Female; Fetal Blood; Fetus; Hypertension; Nitroglyce | 1980 |
[Sublingual use of nitroglycerin in the emergency therapy of hypertensive toxicoses in pregnant women].
Topics: Administration, Oral; Female; Humans; Hypertension; Nitroglycerin; Pre-Eclampsia; Pregnancy; Tablets | 1982 |
The use of intravenous nitroglycerin for emergency cervico-uterine relaxation.
Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Cervix Uteri; Emergencies; Female; Humans; Inje | 1995 |
Prostacyclin contributes to nitroglycerin-mediated relaxation of human umbilical arteries.
Topics: Epoprostenol; Female; Humans; In Vitro Techniques; Indomethacin; Molsidomine; Muscle Relaxation; Mus | 1993 |
Nitroglycerin for fetal head entrapment during vaginal breech delivery?
Topics: Breech Presentation; Cesarean Section; Female; Humans; Muscle Relaxation; Nitroglycerin; Obstetric L | 1995 |
Effects of nitroglycerin on the uterine and umbilical circulation in severe preeclampsia.
Topics: Blood Pressure; Female; Humans; Nitroglycerin; Pre-Eclampsia; Pregnancy; Pulsatile Flow; Regional Bl | 1995 |
Role of nitric oxide on vasorelaxation in human umbilical artery.
Topics: Caffeine; Calcimycin; Calcium; Cyclic GMP; Female; Histamine; Humans; In Vitro Techniques; Nitric Ox | 1995 |
Alternating nitroglycerin and syntocinon to facilitate uterine exploration and removal of an adherent placenta.
Topics: Adult; Blood Pressure; Calcium; Ephedrine; Female; Humans; Infusions, Intravenous; Myosins; Nitrogly | 1995 |
Properties of a lactate-induced relaxation in human placental arteries and veins.
Topics: Analysis of Variance; Arginine; Arteries; Colforsin; Cyanides; Dinoprost; Dose-Response Relationship | 1993 |
Arrest of preterm labour and prolongation of gestation with glyceryl trinitrate, a nitric oxide donor.
Topics: Administration, Cutaneous; Female; Humans; Nitroglycerin; Obstetric Labor, Premature; Pregnancy; Ute | 1994 |
Glyceryl trinitrate in management of preterm labour.
Topics: Administration, Cutaneous; Female; Humans; Nitroglycerin; Obstetric Labor, Premature; Pregnancy; Toc | 1994 |
Glyceryl trinitrate in management of preterm labour.
Topics: Administration, Cutaneous; Female; Humans; Nitroglycerin; Obstetric Labor, Premature; Pregnancy; Toc | 1994 |
[Inhibition of spontaneous uterine contractions by nitroglycerin].
Topics: Female; Humans; Myometrium; Nitroglycerin; Organ Culture Techniques; Pregnancy; Uterine Contraction | 1994 |
Intravenous nitroglycerin for intrapartum external version of the second twin.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Female; Humans; Injections, Intravenous; Labor, | 1994 |
Inhibition of nitric oxide synthesis in rats during pregnancy produces signs similar to those of preeclampsia.
Topics: Animals; Arginine; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Female; Fetal Deat | 1993 |
Gestational changes in endothelium-dependent vasorelaxation in human umbilical artery.
Topics: Arginine; Biological Assay; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Histami | 1994 |
Intravenous nitroglycerin as a tocolytic agent for intrapartum external cephalic version.
Topics: Adult; Female; Humans; Injections, Intravenous; Nitroglycerin; Pregnancy; Tocolysis; Version, Fetal | 1993 |
Myocardial infarction in the third trimester of pregnancy secondary to an aortic valve thrombus.
Topics: Adult; Aortic Valve; Female; Heart Valve Prosthesis; Heparin; Humans; Myocardial Infarction; Nifedip | 1993 |
Severe pregnancy-induced hypertension and blood pressure control during general anesthesia: nitroglycerin or opioids, the logical choice?
Topics: Anesthesia, General; Female; Humans; Narcotics; Nitroglycerin; Pre-Eclampsia; Pregnancy | 1993 |
Absence of relaxation to lactate in human placental vessels of pregnancies with severe preeclampsia.
Topics: Adult; Arteries; Colforsin; Female; Humans; Infant, Newborn; Infant, Premature; Lactates; Lactic Aci | 1995 |
The use of small-dose intravenous nitroglycerin in a case of uterine inversion.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Dissociative; Anesthetics, Local; | 1996 |
Pulmonary edema in a woman following fetal surgery.
Topics: Adult; Blood Proteins; Female; Fetal Diseases; Fetus; Hernia, Diaphragmatic; Humans; Intubation, Int | 1996 |
[Reaction of umbilical cord arteries to PGF2 alpha and glycerol trinitrate during the first days post partum].
Topics: Autacoids; Dinoprost; Female; Humans; Infant, Newborn; Nitroglycerin; Oxytocics; Postpartum Period; | 1995 |
[Intravenous use of nitroglycerin in obstetrical emergencies. 9 cases of version by internal manipulations].
Topics: Emergencies; Female; Humans; Injections, Intravenous; Nitroglycerin; Pregnancy; Pregnancy Complicati | 1996 |
Comparison of nitric oxide and prostacyclin in endothelium-dependent vasorelaxation of human umbilical artery at midgestation.
Topics: Endothelium, Vascular; Epoprostenol; Female; Histamine; Humans; Indomethacin; Nitric Oxide; Nitric O | 1996 |
Preterm labour and delivery.
Topics: Adrenergic beta-Agonists; Biomarkers; Female; Humans; Indomethacin; Magnesium; Nitroglycerin; Obstet | 1996 |
Nitroglycerin and uterine relaxation.
Topics: Female; Humans; Infant, Newborn; Male; Nitroglycerin; Pregnancy; Uterus | 1996 |
Radionuclide esophageal emptying and long-acting nitrates (Nitroderm) in childhood achalasia.
Topics: Child; Esophageal Achalasia; Esophagus; Female; Fundoplication; Humans; Nitroglycerin; Organotechnet | 1996 |
[Intravenous use of nitroglycerin for emergency relaxation of the cervix and uterus. A case report].
Topics: Adult; Emergencies; Female; Fetal Membranes, Premature Rupture; Humans; Injections, Intravenous; Nit | 1996 |
Opposing actions of cholinergic agonist and trinitroglycerin on net vascular resistance in perfused rat heart.
Topics: Acetylcholine; Animals; Cholinergic Agonists; Female; Heart; In Vitro Techniques; Methacholine Chlor | 1996 |
Utilization of intravenous nitroglycerin for obstetrical emergencies.
Topics: Adult; Breech Presentation; Female; Humans; Muscle Relaxation; Nitroglycerin; Parasympatholytics; Pr | 1996 |
Treatment of preterm cervical dilatation with glyceryl trinitrate, a nitric oxide donor.
Topics: Administration, Cutaneous; Adult; Female; Humans; Labor Stage, First; Nitroglycerin; Obstetric Labor | 1996 |
Intravenous nitroglycerin for intrapartum internal podalic version of the second non-vertex twin.
Topics: Female; Humans; Infant, Newborn; Muscle Relaxation; Nitroglycerin; Pregnancy; Pregnancy Outcome; Ret | 1996 |
Sublingual aerosol nitroglycerin for uterine relaxation in attempted external version.
Topics: Administration, Sublingual; Aerosols; Blood Pressure; Female; Humans; Muscle Relaxation; Nitroglycer | 1997 |
Safety of intravenous glyceryl trinitrate in management of retained placenta.
Topics: Adult; Analgesia, Obstetrical; Female; Hemodynamics; Humans; Injections, Intravenous; Nitroglycerin; | 1997 |
Fetal and maternal hemodynamic and metabolic effects of maternal nitroglycerin infusions in sheep.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Fetus; Glucose; Heart Rate; Hemod | 1997 |
The use of intravenous nitroglycerin for emergency cervico-uterine relaxation.
Topics: Adult; Cervix Uteri; Emergencies; Female; Humans; Injections, Intravenous; Muscle Relaxation; Muscle | 1997 |
Intravenous nitroglycerin to relieve intrapartum fetal distress related to uterine hyperactivity: a prospective observational study.
Topics: Adult; Analgesia, Obstetrical; Apgar Score; Blood Pressure; Drug Evaluation; Female; Fetal Distress; | 1997 |
Relative potency of nitrovasodilators on human placental vessels from normal and preeclamptic pregnancies.
Topics: Analysis of Variance; Arteries; Dose-Response Relationship, Drug; Female; Humans; Muscle, Smooth, Va | 1997 |
Effects of cGMP and the nitric oxide donors glyceryl trinitrate and sodium nitroprusside on contractions in vitro of isolated myometrial tissue from pregnant women.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Benzopyrans; Calcium Channel Agonists; Calcium Channel Block | 1997 |
Role of the L-arginine nitric oxide pathway in hypoxic fetoplacental vasoconstriction.
Topics: Adult; Arginine; Blood Gas Analysis; Drug Combinations; Female; Fetal Hypoxia; Humans; In Vitro Tech | 1997 |
Treatment of pre-term cervical dilatation with glyceryl trinitrate, a nitric oxide donor.
Topics: Female; Humans; Nitroglycerin; Obstetric Labor, Premature; Pregnancy; Tocolytic Agents; Vasodilator | 1997 |
Placental tissue enhances uterine relaxation by nitroglycerin.
Topics: Acetylcholine; Animals; Female; Nitroglycerin; Phenylephrine; Placenta; Pregnancy; Rats; Rats, Sprag | 1998 |
[Tocolytic effects of nitric oxide. Introduction to an experimental approach].
Topics: Animals; Drug Evaluation, Preclinical; Female; In Vitro Techniques; Molsidomine; Nitric Oxide; Nitri | 1997 |
Intravenous nitroglycerin for rapid uterine relaxation.
Topics: Cesarean Section; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Injections, | 1998 |
Sublingual glyceryl trinitrate for uterine relaxation at Caeserean section--a prospective trial.
Topics: Administration, Sublingual; Apgar Score; Birth Weight; Blood Pressure; Cesarean Section; Female; Hum | 1998 |
Management of the entrapped second twin: the benefits of sublingual glyceryl trinitrate.
Topics: Administration, Sublingual; Adult; Female; Humans; Male; Muscle, Smooth; Nitroglycerin; Obstetric La | 1998 |
Nitroglycerin to facilitate fetal extraction during cesarean delivery.
Topics: Cesarean Section; Extraction, Obstetrical; Female; Humans; Muscle Relaxation; Muscle, Smooth; Nitrog | 1998 |
[Tocolysis with a nitroglycerin patch].
Topics: Administration, Cutaneous; Adult; Female; Fenoterol; Humans; Infant, Newborn; Nitroglycerin; Obstetr | 1998 |
Anaesthetic management for caesarean section combined with removal of phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Alprostadil; Anesthesia, Epidural; Anesthesia, General; Anesthesia, | 1998 |
Expression of nitric oxide synthase in normal and preeclamptic placental tissue and effects of glyceryl trinitrate and shear stress on placental blood flow.
Topics: Blood Flow Velocity; Female; Humans; In Vitro Techniques; NADPH Dehydrogenase; Nitric Oxide Synthase | 1998 |
Effects of transdermal nitroglycerin on impedance to flow in the uterine, umbilical, and fetal middle cerebral arteries in pregnancies complicated by preeclampsia and intrauterine growth retardation.
Topics: Administration, Cutaneous; Adult; Arteries; Blood Flow Velocity; Cerebral Arteries; Female; Fetal Gr | 1998 |
Endothelin-induced contractions in placental arteries is mediated by both ETA- and ETB-receptors.
Topics: Adult; Arteries; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Fem | 1998 |
Intravenous nitroglycerin in obstetrics: a new indication.
Topics: Abruptio Placentae; Adult; Female; Fetal Death; Humans; Injections, Intravenous; Muscle Hypertonia; | 1998 |
Pulmonary edema in obstetric patients is rapidly resolved except in the presence of infection or of nitroglycerin tocolysis after open fetal surgery.
Topics: Critical Care; Female; Fetus; Hemodynamics; Humans; Lung; Nitroglycerin; Obstetric Labor, Premature; | 1998 |
In-utero and neonatal exposure to secondhand smoke causes vascular dysfunction in newborn rats.
Topics: Acetylcholine; Animals; Animals, Newborn; Aorta, Thoracic; Calcimycin; Cotinine; Disease Models, Ani | 1998 |
[Role of beta-blockers in the treatment of mitral stenosis, apropos of 4 cases].
Topics: Adrenergic beta-Antagonists; Adult; Anemia; Anti-Arrhythmia Agents; Digitalis Glycosides; Diuretics; | 1997 |
A novel approach to the management of pregnancies complicated by uteroplacental insufficiency and previous stillbirth.
Topics: Adult; Aspirin; Drug Therapy, Combination; Female; Fetal Death; Fetal Growth Retardation; Fetal Moni | 1998 |
Endothelial function is impaired in fit young adults of low birth weight.
Topics: Adult; Blood Pressure; Brachial Artery; Case-Control Studies; Endothelium, Vascular; Female; Fetal G | 1998 |
Cesarean section in a mother with uncorrected congenital coronary to pulmonary artery fistula.
Topics: Adult; Analgesics, Opioid; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesia, Obstetrical; | 1999 |
Effect of placental tissue on inhibition of uterine contraction by nitric oxide donors.
Topics: Animals; Diethylamines; Female; Gestational Age; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; P | 1999 |
Effects of nitroglycerin and indomethacin on fetal-maternal circulation and on fetal cerebral blood flow and metabolism in sheep.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Brain; Carotid Arteries; Female; Fetus; Heart Rate; He | 1999 |
Nitric oxide donors in pregnancy: fetomaternal hemodynamic effects induced in mild pre-eclampsia and threatened preterm labor.
Topics: Blood Flow Velocity; Blood Pressure; Female; Gestational Age; Heart Rate, Fetal; Hemodynamics; Human | 1999 |
Stimulated nitric oxide release and nitric oxide sensitivity in forearm arterial vasculature during normotensive and preeclamptic pregnancy.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Arteries; Blood Pressure; Brachial Artery; Female; Fore | 1999 |
The effect of nitroglycerin on the gravid uterus in sheep and rabbits.
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Compliance; Female; Heart Rate; In Vitro Techniqu | 2000 |
Alterations in relaxation to lactate and H(2)O(2) in human placental vessels from gestational diabetic pregnancies.
Topics: Adolescent; Adult; Arachidonic Acid; Colforsin; Diabetes, Gestational; Female; Humans; Hydrogen Pero | 2000 |
Role of peroxynitrite in altered fetal-placental vascular reactivity in diabetes or preeclampsia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Angiotensin II; Antihyper | 2000 |
Nitroglycerin application during cesarean delivery: plasma levels, fetal/maternal ratio of nitroglycerin, and effects in newborns.
Topics: Adolescent; Adult; Cesarean Section; Female; Fetal Blood; Humans; Infant, Newborn; Injections, Intra | 2000 |
Comparison of the relaxation effect in vitro of nitroglycerin vs. fenoterol on human myometrial strips.
Topics: Adrenergic beta-Agonists; Dose-Response Relationship, Drug; Female; Fenoterol; Humans; In Vitro Tech | 2000 |
Practice tips. Novel uses for nitroglycerin.
Topics: Adult; Biliary Tract Diseases; Child; Colic; Delivery, Obstetric; Esophageal Spasm, Diffuse; Female; | 2000 |
Randomised, double-blind, placebo controlled pilot study assessing nitroglycerin as a tocolytic.
Topics: Cervical Ripening; Double-Blind Method; Female; Humans; Nitroglycerin; Pilot Projects; Pregnancy; Ra | 2000 |
Presence of placental tissue is necessary for TNG to provide uterine relaxation.
Topics: Adult; Delivery, Obstetric; Female; Humans; Nitroglycerin; Oxytocics; Oxytocin; Placenta; Placenta, | 2000 |
A case of locked twins successfully treated with nitroglycerin sublingually before manual reposition and vaginal delivery.
Topics: Administration, Sublingual; Adult; Aerosols; Female; Humans; Infant, Newborn; Nitroglycerin; Obstetr | 2001 |
Association of maternal endothelial dysfunction with preeclampsia.
Topics: Adult; Antioxidants; Ascorbic Acid; Blood Flow Velocity; Brachial Artery; Case-Control Studies; Endo | 2001 |
Association of maternal endothelial dysfunction with preeclampsia.
Topics: Adult; Antioxidants; Ascorbic Acid; Blood Flow Velocity; Brachial Artery; Case-Control Studies; Endo | 2001 |
Association of maternal endothelial dysfunction with preeclampsia.
Topics: Adult; Antioxidants; Ascorbic Acid; Blood Flow Velocity; Brachial Artery; Case-Control Studies; Endo | 2001 |
Association of maternal endothelial dysfunction with preeclampsia.
Topics: Adult; Antioxidants; Ascorbic Acid; Blood Flow Velocity; Brachial Artery; Case-Control Studies; Endo | 2001 |
Effects of nitrovasodilators on the human fetal-placental circulation in vitro.
Topics: Adolescent; Adult; Antioxidants; Arteries; Chorion; Cysteine; Female; Fetus; Gestational Age; Glutat | 2001 |
Effects of nitric oxide donors on the contractility and prostaglandin synthesis of myometrial strips from pregnant and non-pregnant women.
Topics: Cyclic GMP; Dinoprost; Dinoprostone; Epoprostenol; Female; Humans; Myometrium; Nitric Oxide Donors; | 2001 |
Glyceryl trinitrate ointment as a potential treatment for primary vaginismus.
Topics: Adult; Female; Humans; Male; Nitroglycerin; Ointments; Pregnancy; Sexual Dysfunctions, Psychological | 2001 |
Does nitric oxide play a role in the aetiology of pre-eclampsia?
Topics: Adult; Blotting, Western; Cell Adhesion; Cell Line; Cell Movement; Enzyme Inhibitors; Female; Humans | 2001 |
[Hypertensive crisis, hypertensive emergency. Nitrate spray and ambulance--this can also be wrong].
Topics: Administration, Oral; Aerosols; Ambulances; Emergencies; Female; Humans; Hypertension, Malignant; Ni | 2001 |
[Therapeutic effects of nitroglycerin on pregnancy induced hypertension].
Topics: Adult; Blood Pressure; Female; Fetal Growth Retardation; Humans; Hypertension; Nitroglycerin; Placen | 2001 |
Re: glyceryl trinitrate (GTN) patches are unsuitable in hypertensive pregnancy.
Topics: Administration, Cutaneous; Female; Headache; Humans; Nitroglycerin; Pre-Eclampsia; Pregnancy; Random | 2001 |
Effects of nitric oxide donors and inhibitors of nitric oxide signalling on endothelin- and serotonin-induced contractions in human placental arteries.
Topics: Adult; Aminoquinolines; Cyclic GMP; Dose-Response Relationship, Drug; Endothelin-1; Female; Humans; | 2002 |
[Contribution of diagnostic ultrasonography in cases of repeated embryonic implantation failure in fertilization in vitro].
Topics: Arteries; Aspirin; Embryo Implantation; Embryo Transfer; Female; Fertilization in Vitro; Humans; Lut | 2001 |
Central neuraxial blockade promotes external cephalic version success after a failed attempt.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Breech Presentation; Cesarean Section; Female; H | 2002 |
Effects of age on aortic pressure-diameter and elastic stiffness-stress relationships in unanesthetized sheep.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Aorta; Blood Pressure; Elasticity; Female; Hemodyn | 1979 |
Placental transfer of nitroglycerin.
Topics: Female; Humans; Maternal-Fetal Exchange; Nitroglycerin; Pregnancy; Succinylcholine | 1979 |
The use of nitroglycerin to control severe hypertension of pregnancy during cesarean section.
Topics: Adult; Cesarean Section; Female; Humans; Hypertension; Nitroglycerin; Pregnancy; Pregnancy Complicat | 1979 |
Angiotensin II increases uterine vascular resistance in pregnant and nonpregnant rabbits.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Nitroglycerin; Ph | 1977 |
A species and developmental comparison of trinitroglycerin metabolism in vitro.
Topics: Adult; Aged; Aging; Animals; Dogs; Embryo, Mammalian; Female; Gestational Age; Haplorhini; Humans; I | 1977 |
Reduction in human fetal umbilical-placental vascular resistance by glyceryl trinitrate.
Topics: Adult; Blood Flow Velocity; Female; Fetus; Humans; Nitroglycerin; Placenta; Pregnancy; Regional Bloo | 1992 |
Studies of autacoid responsiveness and endothelium dependency in human umbilical arteries.
Topics: Autacoids; Dinoprost; Dinoprostone; Endothelium, Vascular; Female; Humans; Methylene Blue; Microscop | 1992 |
Antepartum uterine relaxation with nitroglycerin at caesarean delivery.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Bupivacaine; Cesarean Section; Female; Humans; I | 1992 |
Intravenous nitroglycerin for uterine relaxation of an inverted uterus.
Topics: Adult; Female; Humans; Injections, Intravenous; Nitroglycerin; Pregnancy; Pregnancy Complications; U | 1992 |
Breech extraction facilitated by glyceryl trinitrate sublingual spray.
Topics: Adult; Aerosols; Breech Presentation; Extraction, Obstetrical; Female; Humans; Nitroglycerin; Pregna | 1991 |
Attenuation of the vasoconstrictor effects of thromboxane and endothelin by nitric oxide in the human fetal-placental circulation.
Topics: Acetylcholine; Arginine; Calcimycin; Endothelins; Female; Fetus; Humans; Nitric Oxide; Nitroarginine | 1992 |
Uterine relaxation can be life saving.
Topics: Cesarean Section; Female; Humans; Muscle Relaxation; Muscle, Smooth; Nitroglycerin; Obstetric Labor | 1991 |
The hemodynamic effects of intubation during nitroglycerin infusion in severe preeclampsia.
Topics: Acute Disease; Adolescent; Adult; Anesthesia, General; Anesthesia, Obstetrical; Blood Volume; Drug E | 1991 |
Intravenous nitroglycerin aids manual extraction of a retained placenta.
Topics: Female; Humans; Injections, Intravenous; Nitroglycerin; Placenta Diseases; Pregnancy; Puerperal Diso | 1990 |
Anaesthetic management of myocardial infarction in a parturient.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Cardiac Catheterization; Cesarean Section; Fem | 1990 |
Relaxation of bovine mesenteric arteries by glyceryl trinitrate and other nitro-compounds: evidence for partly different mechanisms of action.
Topics: Aminoquinolines; Animals; Cattle; Female; Isosorbide Dinitrate; Mesenteric Arteries; Mice; Muscle Re | 1990 |
[Ruptured aneurysm during pregnancy. Case report].
Topics: Adult; Female; Fetal Monitoring; Heart Rate, Fetal; Humans; Hypotension, Controlled; Intracranial An | 1987 |
Intravenous nitroglycerin for uterine relaxation in the postpartum patient with retained placenta.
Topics: Adult; Female; Humans; Infusions, Intravenous; Nitroglycerin; Placenta; Pregnancy; Puerperal Disorde | 1989 |
Role of nitroglycerin ointment in preventing the pressure response during caesarean section in pre-eclampsia.
Topics: Cesarean Section; Female; Humans; Hypertension; Intubation, Intratracheal; Laryngoscopy; Nitroglycer | 1989 |
Role of intravenous nitroglycerin in the treatment of severe pregnancy-induced hypertension complicated by pulmonary edema.
Topics: Female; Hemodynamics; Humans; Infusions, Parenteral; Nitroglycerin; Oxygen Consumption; Pre-Eclampsi | 1986 |
Ventricular tachycardia and hypotension with amniotic fluid embolism during cesarean section.
Topics: Adult; Anesthesia, Obstetrical; Blood Pressure; Bupivacaine; Cesarean Section; Diazepam; Electrocard | 1986 |
Cardiovascular alterations in severe pregnancy-induced hypertension: effects of intravenous nitroglycerin coupled with blood volume expansion.
Topics: Adolescent; Adult; Albumins; Blood Pressure; Blood Volume; Cardiac Output; Female; Fetal Heart; Huma | 1986 |
[Teratological test of 10% nitroglycerin (NT-1 ointment) in rabbits].
Topics: Abnormalities, Drug-Induced; Administration, Cutaneous; Animals; Embryonic and Fetal Development; Fe | 1986 |
Response of lamb ductus arteriosus to nitroglycerin and nitroprusside.
Topics: Alprostadil; Animals; Ductus Arteriosus; Female; Ferricyanides; Nitrogen; Nitroglycerin; Nitroprussi | 1988 |
Role of volume expansion in severe pre-eclampsia.
Topics: Antihypertensive Agents; Blood Pressure; Blood Volume; Cardiac Catheterization; Colloids; Delivery, | 1988 |
[Drug therapy in eclampsia].
Topics: Blood Pressure; Cerebrovascular Circulation; Cesarean Section; Dexamethasone; Dihydralazine; Dobutam | 1985 |
The use of nitroglycerin in preventing the hypertensive response to tracheal intubation in severe preeclampsia.
Topics: Adult; Cesarean Section; Drug Evaluation; Female; Fetus; Humans; Hypertension; Infant, Newborn; Infu | 1985 |
The influence of pharmaca on the oxygen induced constriction of the human umbilical cord artery.
Topics: Drug Interactions; Female; Humans; In Vitro Techniques; Isoproterenol; Methysergide; Nitroglycerin; | 1974 |
Myocardial infarction in pregnancy. Case report and brief review.
Topics: Adult; Analgesics; Electrocardiography; Female; Gestational Age; Humans; Myocardial Infarction; Nitr | 1973 |
Effect of certain drugs on perfused human placenta. 8. Angiotensin-II antagonists.
Topics: Acetates; Angiotensin II; Atropine; Blood Pressure Determination; Cobalt; Cocaine; Cyproheptadine; D | 1968 |
[Sheehan's disease followed by severe arterial hypertension with right renal artery stenosis. Discussion of the role of hypopituitarism in atherogenesis].
Topics: Adrenal Cortex Hormones; Adult; Androgens; Arteriosclerosis; Clofibrate; Coronary Disease; Female; H | 1973 |
Effect of certain drugs on perfused human placenta. IX. Mode of action of angiotensin.
Topics: Angiotensin II; Blood Vessels; Constriction; Dipyridamole; Ethanolamines; Female; Humans; Hydralazin | 1969 |
Homicide and nitroglycerin: a case of drug interaction?
Topics: Adult; Drug Interactions; Female; Humans; Morphine; Nitroglycerin; Pregnancy | 1972 |
Smooth muscle relaxants: dissociation between resting membrane potential and resting tension in rat myometrium.
Topics: Animals; Catecholamines; Epinephrine; Female; In Vitro Techniques; Isoproterenol; Membrane Potential | 1969 |
A comparison of the effects of various smooth muscle relaxants on the electrical and mechanical activity of rat uterus.
Topics: Action Potentials; Animals; Calcium; Cell Membrane; Electricity; Epinephrine; Female; In Vitro Techn | 1969 |
[Evaluation of pulmonary hemodynamics on the basis of rheography of the lungs and gas exchange in pregnant women with mitral diseases].
Topics: Adolescent; Adult; Electrocardiography; Female; Hemodynamics; Humans; Lung; Mitral Valve Insufficien | 1970 |
Differential reactivity of the myoendometrial and placental vasculatures: vasodilatation.
Topics: Animals; Cyanides; Dilatation; Female; Gestational Age; Ischemia; Isoproterenol; Nitroglycerin; Plac | 1971 |