nitroglycerin has been researched along with Pre-Eclampsia in 44 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " administration of nitroglycerine as an antihypertensive agent in the management of pre-eclampsia is scarce." | 9.13 | Efficacy of nitroglycerine infusion versus sublingual nifedipine in severe pre-eclampsia: a randomized, triple-blind, controlled trial. ( Gordillo-Moscoso, A; Hernández-Sierra, JF; Mandeville, PB; Manzur-Verástegui, S; Rodríguez-Martínez, M, 2008) |
| "To evaluate the effect of transdermal nitroglycerin on Doppler velocity waveforms of the uterine, umbilical and fetal middle cerebral arteries in patients with severe pre-eclampsia." | 7.77 | Transdermal nitroglycerin in patients with severe pre-eclampsia with placental insufficiency: effect on uterine, umbilical and fetal middle cerebral artery resistance indices. ( Gonçalves, LF; Pires, MM; Trapani, A, 2011) |
| "Intravenous nitroglycerin would appear to be an ideal agent for the treatment of severe pregnancy-induced hypertension complicated by cardiogenic pulmonary edema." | 7.67 | Role of intravenous nitroglycerin in the treatment of severe pregnancy-induced hypertension complicated by pulmonary edema. ( Cotton, DB; Dorman, KF; Jones, MM; Joyce, TH; Longmire, S; Tessem, J, 1986) |
| "Seventeen patients with preeclampsia were treated with a nitroglycerin patch, 10 mg per 24 hours, for three consecutive days between 28 and 36 weeks' gestation." | 5.30 | Effects of transdermal nitroglycerin on impedance to flow in the uterine, umbilical, and fetal middle cerebral arteries in pregnancies complicated by preeclampsia and intrauterine growth retardation. ( Cacciatore, B; Halmesmäki, E; Kaaja, R; Teramo, K; Ylikorkala, O, 1998) |
| "Although obstetric pulmonary edema is associated with extensive radiographic infiltrates and severe hypoxemia, resolution occurs rapidly in most patients, limiting the need for intensive care support." | 5.30 | Pulmonary edema in obstetric patients is rapidly resolved except in the presence of infection or of nitroglycerin tocolysis after open fetal surgery. ( Burlingame, JM; DiFederico, EM; Harrison, M; Kilpatrick, SJ; Matthay, MA, 1998) |
| "25 micrograms/kg per minute with stepwise dosage increases until a diastolic blood pressure (BP) of 100 mmHg was achieved." | 5.29 | Effects of nitroglycerin on the uterine and umbilical circulation in severe preeclampsia. ( Carlström, K; Grunewald, C; Kublickas, M; Lunell, NO; Nisell, H, 1995) |
| " administration of nitroglycerine as an antihypertensive agent in the management of pre-eclampsia is scarce." | 5.13 | Efficacy of nitroglycerine infusion versus sublingual nifedipine in severe pre-eclampsia: a randomized, triple-blind, controlled trial. ( Gordillo-Moscoso, A; Hernández-Sierra, JF; Mandeville, PB; Manzur-Verástegui, S; Rodríguez-Martínez, M, 2008) |
| "To evaluate the effectiveness of nitroglycerin as a uterine relaxant for preterm labour, fetal extraction at Caesarean section, external version, embryo transfer, cervical dilation for first trimester pregnancy termination, and primary dysmenorrhea." | 4.81 | Nitroglycerin as a uterine relaxant: a systematic review. ( Kung, R; Morgan, PJ; Tarshis, J, 2002) |
| " Administration of nitroglycerin at 200 μg to relax uterine smooth muscles and the application of fundal pressure led to severe bradycardia and loss of consciousness, followed by cardiac arrest." | 3.85 | Neurally Mediated Syncope During Cesarean Delivery: A Case Report. ( Kusumoto, G; Nakamori, E; Sato, S; Shigematsu, K; Yamaura, K, 2017) |
| "To evaluate the effect of transdermal nitroglycerin on Doppler velocity waveforms of the uterine, umbilical and fetal middle cerebral arteries in patients with severe pre-eclampsia." | 3.77 | Transdermal nitroglycerin in patients with severe pre-eclampsia with placental insufficiency: effect on uterine, umbilical and fetal middle cerebral artery resistance indices. ( Gonçalves, LF; Pires, MM; Trapani, A, 2011) |
| "We studied the effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam (a dopamine D1-agonist) on isolated human umbilical arteries (HUA) from patients classified as normotensive and with pregnancy-induced hypertension (PIH)." | 3.72 | The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery. ( Arias, ME; Levy, JH; Sato, N; Szlam, F; Tanaka, KA; Tsuda, A, 2003) |
| "To our knowledge, this is the first time that a combination of aspirin and glyceryl trinitrate (GTN) has been used in the prophylaxis of preeclampsia and fetal growth retardation, and their use associated with not only Doppler screening of the uterine arteries but also regular Doppler follow-up of the fetal arterial and venous circulation." | 3.70 | A novel approach to the management of pregnancies complicated by uteroplacental insufficiency and previous stillbirth. ( Black, RS; Campbell, S; Lees, CC; Oyelese, KO, 1998) |
| "Intravenous nitroglycerin would appear to be an ideal agent for the treatment of severe pregnancy-induced hypertension complicated by cardiogenic pulmonary edema." | 3.67 | Role of intravenous nitroglycerin in the treatment of severe pregnancy-induced hypertension complicated by pulmonary edema. ( Cotton, DB; Dorman, KF; Jones, MM; Joyce, TH; Longmire, S; Tessem, J, 1986) |
| "Fifty five women with preeclampsia, eclampsia, and HELLP syndrome administered GTN infusion for the management of hypertension were studied." | 2.71 | The effect of glyceryl trinitrate on hypertension in women with severe preeclampsia, HELLP syndrome, and eclampsia. ( Cetin, A; Cetin, M; Duran, B; Guvenal, T; Imir, AG; Yurtcu, N, 2004) |
| " The aim of this study was to determine whether pre-eclampsia and its complications could be prevented by the long-term use of nitric oxide donors in a group of women identified to be at risk on the basis of abnormal uterine artery Doppler measurements." | 2.69 | The efficacy and fetal-maternal cardiovascular effects of transdermal glyceryl trinitrate in the prophylaxis of pre-eclampsia and its complications: a randomized double-blind placebo-controlled trial. ( Black, R; Byiers, S; Campbell, S; Harrington, K; Lees, C; Romanini, C; Valensise, H, 1998) |
| " Although not causal, endothelial dysfunction and reduced nitric oxide bioavailability are likely to play an important role in the maternal and fetal pathophysiology of this condition." | 2.50 | The nitric oxide pathway and possible therapeutic options in pre-eclampsia. ( Everett, TR; Johal, T; Lees, CC; Wilkinson, IB, 2014) |
| " The present data suggest that the oxidative stress and reduced bioavailability of nitric oxide may contribute to attenuation of vasodilator responses to ACh and Ang II, and hyperreactivity to Ang II in the mesentery of preeclamptic rat, which may contribute to the increased peripheral vascular resistance and BP, as well as intrauterine growth restriction in L-NAME-induced PE." | 1.48 | Differential responses of mesenteric arterial bed to vasoactive substances in L-NAME-induced preeclampsia: Role of oxidative stress and endothelial dysfunction. ( Amaral, TAS; Carvalho, LCRM; Costa, CA; Moura, RS; Ognibene, DT; Resende, AC; Rocha, APM, 2018) |
| "A total of 113 women with previous preeclampsia (n = 35 with recurrent episodes; n = 78 with a single episode) and 48 women with previous uncomplicated pregnancies, all of whom were at least 3 months (median, 3 years) postpartum." | 1.31 | Association of maternal endothelial dysfunction with preeclampsia. ( Chambers, JC; De Swiet, M; Fusi, L; Haskard, DO; Kooner, JS; Malik, IS, 2001) |
| "Seventeen patients with preeclampsia were treated with a nitroglycerin patch, 10 mg per 24 hours, for three consecutive days between 28 and 36 weeks' gestation." | 1.30 | Effects of transdermal nitroglycerin on impedance to flow in the uterine, umbilical, and fetal middle cerebral arteries in pregnancies complicated by preeclampsia and intrauterine growth retardation. ( Cacciatore, B; Halmesmäki, E; Kaaja, R; Teramo, K; Ylikorkala, O, 1998) |
| "Although obstetric pulmonary edema is associated with extensive radiographic infiltrates and severe hypoxemia, resolution occurs rapidly in most patients, limiting the need for intensive care support." | 1.30 | Pulmonary edema in obstetric patients is rapidly resolved except in the presence of infection or of nitroglycerin tocolysis after open fetal surgery. ( Burlingame, JM; DiFederico, EM; Harrison, M; Kilpatrick, SJ; Matthay, MA, 1998) |
| "25 micrograms/kg per minute with stepwise dosage increases until a diastolic blood pressure (BP) of 100 mmHg was achieved." | 1.29 | Effects of nitroglycerin on the uterine and umbilical circulation in severe preeclampsia. ( Carlström, K; Grunewald, C; Kublickas, M; Lunell, NO; Nisell, H, 1995) |
| "These signs are similar to those of preeclampsia and indicate that an alteration in nitric oxide synthesis may be one of the factors responsible for this disorder." | 1.29 | Inhibition of nitric oxide synthesis in rats during pregnancy produces signs similar to those of preeclampsia. ( Garfield, RE; Yallampalli, C, 1993) |
| "In severe preeclampsia absence of lactate-induced dilatation of placental vessels may contribute to the fetal complications associated with impaired blood flow and vasospasm." | 1.29 | Absence of relaxation to lactate in human placental vessels of pregnancies with severe preeclampsia. ( Fayngersh, RP; Figueroa, R; Jiang, H; Martinez, E; Omar, HA; Tejani, N; Wolin, MS, 1995) |
| "Nitroglycerin was detected in all but two samples of foetal arterial blood but the foetal/maternal artery ratio was only 0." | 1.26 | Plasma levels and cardiovascular effect of nitroglycerin in pregnant sheep. ( Busch, MD; de Rosayro, M; Hill, AB; Kirsh, MM; Nahrwold, ML; Tait, AR, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (22.73) | 18.7374 |
| 1990's | 14 (31.82) | 18.2507 |
| 2000's | 13 (29.55) | 29.6817 |
| 2010's | 7 (15.91) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Robb, KP | 1 |
| Cotechini, T | 1 |
| Allaire, C | 1 |
| Sperou, A | 1 |
| Graham, CH | 3 |
| Amaral, TAS | 1 |
| Ognibene, DT | 1 |
| Carvalho, LCRM | 1 |
| Rocha, APM | 1 |
| Costa, CA | 1 |
| Moura, RS | 1 |
| Resende, AC | 1 |
| Arulkumaran, N | 1 |
| Lightstone, L | 1 |
| Johal, T | 1 |
| Lees, CC | 2 |
| Everett, TR | 1 |
| Wilkinson, IB | 1 |
| Sato, S | 1 |
| Nakamori, E | 1 |
| Kusumoto, G | 1 |
| Shigematsu, K | 1 |
| Yamaura, K | 1 |
| Pàez, O | 1 |
| Alfie, J | 1 |
| Gorosito, M | 1 |
| Puleio, P | 1 |
| de Maria, M | 1 |
| Prieto, N | 1 |
| Majul, C | 1 |
| Trapani, A | 1 |
| Gonçalves, LF | 1 |
| Pires, MM | 1 |
| Espinoza, J | 1 |
| Espinoza, AF | 1 |
| Morgan, PJ | 1 |
| Kung, R | 1 |
| Tarshis, J | 1 |
| Wang, CH | 1 |
| Li, ZY | 1 |
| Xiao, GX | 1 |
| Sato, N | 1 |
| Tanaka, KA | 1 |
| Szlam, F | 1 |
| Tsuda, A | 1 |
| Arias, ME | 1 |
| Levy, JH | 1 |
| Finsterer, J | 1 |
| Schlager, T | 1 |
| Kopsa, W | 1 |
| Wild, E | 1 |
| BRILL, HM | 1 |
| LONG, JS | 1 |
| KLAWANS, AH | 1 |
| GOLDEN, M | 1 |
| SEAMAN, I | 1 |
| MORRIS, N | 1 |
| TOMKINSON, JS | 1 |
| O'CONNOR, BJ | 1 |
| RODDICK, JW | 1 |
| BENARON, HB | 1 |
| GARDINER, J | 1 |
| HERDAN, G | 1 |
| Cetin, A | 1 |
| Yurtcu, N | 1 |
| Guvenal, T | 1 |
| Imir, AG | 1 |
| Duran, B | 1 |
| Cetin, M | 1 |
| Belkacemi, L | 1 |
| Bainbridge, SA | 1 |
| Dickinson, MA | 1 |
| Smith, GN | 1 |
| Meher, S | 1 |
| Duley, L | 1 |
| Manzur-Verástegui, S | 1 |
| Mandeville, PB | 1 |
| Gordillo-Moscoso, A | 1 |
| Hernández-Sierra, JF | 1 |
| Rodríguez-Martínez, M | 1 |
| de Rosayro, M | 1 |
| Nahrwold, ML | 1 |
| Hill, AB | 1 |
| Tait, AR | 1 |
| Busch, MD | 1 |
| Kirsh, MM | 1 |
| Federmesser, KM | 1 |
| Pilipenko, NV | 1 |
| Sologubov, AP | 1 |
| Grunewald, C | 1 |
| Kublickas, M | 1 |
| Carlström, K | 1 |
| Lunell, NO | 1 |
| Nisell, H | 1 |
| Ramsay, B | 1 |
| De Belder, A | 1 |
| Campbell, S | 3 |
| Moncada, S | 1 |
| Martin, JF | 1 |
| Yallampalli, C | 1 |
| Garfield, RE | 1 |
| Downing, JW | 1 |
| Figueroa, R | 1 |
| Martinez, E | 1 |
| Fayngersh, RP | 1 |
| Jiang, H | 1 |
| Omar, HA | 1 |
| Tejani, N | 1 |
| Wolin, MS | 1 |
| González, C | 1 |
| Cruz, MA | 1 |
| Gallardo, V | 1 |
| Miguel, P | 1 |
| Carrasco, G | 1 |
| Poranen, AK | 1 |
| Aubry, J | 1 |
| Kujari, H | 1 |
| Ekblad, U | 1 |
| Cacciatore, B | 1 |
| Halmesmäki, E | 1 |
| Kaaja, R | 1 |
| Teramo, K | 1 |
| Ylikorkala, O | 1 |
| DiFederico, EM | 1 |
| Burlingame, JM | 1 |
| Kilpatrick, SJ | 1 |
| Harrison, M | 1 |
| Matthay, MA | 1 |
| Lees, C | 1 |
| Valensise, H | 1 |
| Black, R | 1 |
| Harrington, K | 1 |
| Byiers, S | 1 |
| Romanini, C | 1 |
| Oyelese, KO | 1 |
| Black, RS | 1 |
| Luzi, G | 1 |
| Caserta, G | 1 |
| Iammarino, G | 1 |
| Clerici, G | 1 |
| Di Renzo, GC | 1 |
| Anumba, DO | 1 |
| Ford, GA | 1 |
| Boys, RJ | 1 |
| Robson, SC | 1 |
| Kossenjans, W | 1 |
| Eis, A | 1 |
| Sahay, R | 1 |
| Brockman, D | 1 |
| Myatt, L | 1 |
| Chambers, JC | 1 |
| Fusi, L | 1 |
| Malik, IS | 1 |
| Haskard, DO | 1 |
| De Swiet, M | 1 |
| Kooner, JS | 1 |
| Postovit, LM | 1 |
| Adams, MA | 1 |
| Davis, DG | 1 |
| Brown, PM | 1 |
| Longmire, S | 3 |
| Leduc, L | 1 |
| Jones, MM | 2 |
| Hawkins, JL | 1 |
| Joyce, TH | 2 |
| Cotton, DB | 3 |
| Rudra, A | 1 |
| Das, B | 1 |
| Adhikary, D | 1 |
| Dorman, KF | 1 |
| Tessem, J | 2 |
| Kirshon, B | 1 |
| Moise, KJ | 1 |
| Jones, M | 1 |
| Joyce, TA | 1 |
| Hood, DD | 1 |
| Dewan, DM | 1 |
| James, FM | 1 |
| Floyd, HM | 1 |
| Bogard, TD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Use of Sildenafil Citrate in Management of Mild Pre-eclampsia: A Randomized Controlled Trial[NCT03262961] | Phase 2/Phase 3 | 80 participants (Anticipated) | Interventional | 2016-09-15 | Recruiting | ||
| Efficacy and Safety of L Arginine to Prevent Preeclampsia in High Risk Pregnancies[NCT02363348] | Phase 3 | 96 participants (Actual) | Interventional | 2010-08-31 | Completed | ||
| Exploratory Study. Endothelial Function and Vascular Biomarkers: Predictive Indicators of the Progression From Gestational Hypertension to Preeclampsia?[NCT04520048] | 110 participants (Anticipated) | Interventional | 2023-08-24 | Recruiting | |||
| Assessment of the Cardiovascular Risk Profile of Infants Exposed to Pre-eclampsia in Utero[NCT05091827] | 234 participants (Anticipated) | Observational | 2021-11-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for nitroglycerin and Pre-Eclampsia
| Article | Year |
|---|---|
Severe pre-eclampsia and hypertensive crises.
Topics: Administration, Intravenous; Administration, Oral; Antihypertensive Agents; Critical Care; Early Dia | 2013 |
The nitric oxide pathway and possible therapeutic options in pre-eclampsia.
Topics: Aldehyde Oxidoreductases; Clinical Trials as Topic; Endothelium, Vascular; Female; Humans; Isosorbid | 2014 |
Nitroglycerin as a uterine relaxant: a systematic review.
Topics: Cesarean Section; Dysmenorrhea; Embryo Transfer; Female; Humans; Nitroglycerin; Obstetric Labor, Pre | 2002 |
Nitric oxide for preventing pre-eclampsia and its complications.
Topics: Female; Humans; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Pre-Eclampsia; Pregnancy; Randomiz | 2007 |
4 trials available for nitroglycerin and Pre-Eclampsia
| Article | Year |
|---|---|
The effect of glyceryl trinitrate on hypertension in women with severe preeclampsia, HELLP syndrome, and eclampsia.
Topics: Adult; Aspartate Aminotransferases; Bilirubin; Biomarkers; Blood Platelets; Blood Pressure; Diastole | 2004 |
Efficacy of nitroglycerine infusion versus sublingual nifedipine in severe pre-eclampsia: a randomized, triple-blind, controlled trial.
Topics: Administration, Sublingual; Adult; Female; Humans; Injections, Intravenous; Magnesium Sulfate; Nifed | 2008 |
A nitric oxide donor improves uterine artery diastolic blood flow in normal early pregnancy and in women at high risk of pre-eclampsia.
Topics: Adaptation, Physiological; Blood Flow Velocity; Diastole; Epoprostenol; Female; Humans; Infusions, I | 1994 |
The efficacy and fetal-maternal cardiovascular effects of transdermal glyceryl trinitrate in the prophylaxis of pre-eclampsia and its complications: a randomized double-blind placebo-controlled trial.
Topics: Administration, Cutaneous; Adult; Arteries; Cardiovascular System; Double-Blind Method; Female; Hemo | 1998 |
36 other studies available for nitroglycerin and Pre-Eclampsia
| Article | Year |
|---|---|
Inflammation-induced fetal growth restriction in rats is associated with increased placental HIF-1α accumulation.
Topics: Animals; Disease Models, Animal; Female; Fetal Growth Retardation; Gene Expression Regulation; Gesta | 2017 |
Differential responses of mesenteric arterial bed to vasoactive substances in L-NAME-induced preeclampsia: Role of oxidative stress and endothelial dysfunction.
Topics: Acetylcholine; Angiotensin II; Animals; Arginine; Blood Pressure; Enzyme Inhibitors; Female; Fetal G | 2018 |
Neurally Mediated Syncope During Cesarean Delivery: A Case Report.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Bradycardia; Cardiopulmonary Resuscitation; Cesa | 2017 |
Parallel decrease in arterial distensibility and in endothelium-dependent dilatation in young women with a history of pre-eclampsia.
Topics: Adolescent; Adult; Birth Weight; Blood Flow Velocity; Carotid Arteries; Case-Control Studies; Cross- | 2009 |
Transdermal nitroglycerin in patients with severe pre-eclampsia with placental insufficiency: effect on uterine, umbilical and fetal middle cerebral artery resistance indices.
Topics: Adult; Blood Flow Velocity; Female; Gestational Age; Humans; Middle Cerebral Artery; Nitroglycerin; | 2011 |
Pre-eclampsia: a maternal manifestation of a fetal adaptive response?
Topics: Blood Flow Velocity; Female; Humans; Middle Cerebral Artery; Nitroglycerin; Placental Insufficiency; | 2011 |
[Role of nitric oxide in pathogenesis of pregnancy induced hypertension].
Topics: Animals; Endothelin-1; Female; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nit | 2000 |
The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Dopamine; Dose-Response Relation | 2003 |
Nitroglycerin-aggravated pre-eclamptic posterior reversible encephalopathy syndrome (PRES).
Topics: Adult; Brain; Brain Diseases; Female; Humans; Magnetic Resonance Imaging; Nitroglycerin; Pre-Eclamps | 2003 |
The nitroglycerin flicker fusion threshold test in toxemia of pregnancy.
Topics: Female; Flicker Fusion; Nitroglycerin; Pre-Eclampsia; Pregnancy; Vision, Ocular | 1952 |
The significance of the nitroglycerine flicker fusion response in normal subjects and in pregnancy.
Topics: Female; Flicker Fusion; Humans; Nitroglycerin; Pre-Eclampsia; Pregnancy; Vision, Ocular | 1953 |
Flicker fusion threshold; nitroglycerine response as a screening test for toxemia of pregnancy.
Topics: Female; Flicker Fusion; Nitrites; Nitroglycerin; Pre-Eclampsia; Pregnancy; Vision, Ocular | 1954 |
A statistical evaluation of the nitroglycerine flicker-fusion threshold test and the weight-gain sign in the prediction of the clinical syndrome of pre-eclampsia.
Topics: Body Weight; Female; Humans; Nitroglycerin; Pre-Eclampsia; Pregnancy; Vision Tests; Vision, Ocular; | 1957 |
Glyceryl trinitrate inhibits hypoxia/reoxygenation-induced apoptosis in the syncytiotrophoblast of the human placenta: therapeutic implications for preeclampsia.
Topics: Aldehydes; Apoptosis; Blotting, Western; Caspase 3; Collagen Type XI; Female; Humans; Hypoxia; Immun | 2007 |
Plasma levels and cardiovascular effect of nitroglycerin in pregnant sheep.
Topics: Animals; Blood Pressure; Cardiovascular System; Female; Fetal Blood; Fetus; Hypertension; Nitroglyce | 1980 |
[Sublingual use of nitroglycerin in the emergency therapy of hypertensive toxicoses in pregnant women].
Topics: Administration, Oral; Female; Humans; Hypertension; Nitroglycerin; Pre-Eclampsia; Pregnancy; Tablets | 1982 |
Effects of nitroglycerin on the uterine and umbilical circulation in severe preeclampsia.
Topics: Blood Pressure; Female; Humans; Nitroglycerin; Pre-Eclampsia; Pregnancy; Pulsatile Flow; Regional Bl | 1995 |
Inhibition of nitric oxide synthesis in rats during pregnancy produces signs similar to those of preeclampsia.
Topics: Animals; Arginine; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Female; Fetal Deat | 1993 |
Severe pregnancy-induced hypertension and blood pressure control during general anesthesia: nitroglycerin or opioids, the logical choice?
Topics: Anesthesia, General; Female; Humans; Narcotics; Nitroglycerin; Pre-Eclampsia; Pregnancy | 1993 |
Absence of relaxation to lactate in human placental vessels of pregnancies with severe preeclampsia.
Topics: Adult; Arteries; Colforsin; Female; Humans; Infant, Newborn; Infant, Premature; Lactates; Lactic Aci | 1995 |
Relative potency of nitrovasodilators on human placental vessels from normal and preeclamptic pregnancies.
Topics: Analysis of Variance; Arteries; Dose-Response Relationship, Drug; Female; Humans; Muscle, Smooth, Va | 1997 |
Expression of nitric oxide synthase in normal and preeclamptic placental tissue and effects of glyceryl trinitrate and shear stress on placental blood flow.
Topics: Blood Flow Velocity; Female; Humans; In Vitro Techniques; NADPH Dehydrogenase; Nitric Oxide Synthase | 1998 |
Effects of transdermal nitroglycerin on impedance to flow in the uterine, umbilical, and fetal middle cerebral arteries in pregnancies complicated by preeclampsia and intrauterine growth retardation.
Topics: Administration, Cutaneous; Adult; Arteries; Blood Flow Velocity; Cerebral Arteries; Female; Fetal Gr | 1998 |
Pulmonary edema in obstetric patients is rapidly resolved except in the presence of infection or of nitroglycerin tocolysis after open fetal surgery.
Topics: Critical Care; Female; Fetus; Hemodynamics; Humans; Lung; Nitroglycerin; Obstetric Labor, Premature; | 1998 |
A novel approach to the management of pregnancies complicated by uteroplacental insufficiency and previous stillbirth.
Topics: Adult; Aspirin; Drug Therapy, Combination; Female; Fetal Death; Fetal Growth Retardation; Fetal Moni | 1998 |
Nitric oxide donors in pregnancy: fetomaternal hemodynamic effects induced in mild pre-eclampsia and threatened preterm labor.
Topics: Blood Flow Velocity; Blood Pressure; Female; Gestational Age; Heart Rate, Fetal; Hemodynamics; Human | 1999 |
Stimulated nitric oxide release and nitric oxide sensitivity in forearm arterial vasculature during normotensive and preeclamptic pregnancy.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Arteries; Blood Pressure; Brachial Artery; Female; Fore | 1999 |
Role of peroxynitrite in altered fetal-placental vascular reactivity in diabetes or preeclampsia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Angiotensin II; Antihyper | 2000 |
Association of maternal endothelial dysfunction with preeclampsia.
Topics: Adult; Antioxidants; Ascorbic Acid; Blood Flow Velocity; Brachial Artery; Case-Control Studies; Endo | 2001 |
Association of maternal endothelial dysfunction with preeclampsia.
Topics: Adult; Antioxidants; Ascorbic Acid; Blood Flow Velocity; Brachial Artery; Case-Control Studies; Endo | 2001 |
Association of maternal endothelial dysfunction with preeclampsia.
Topics: Adult; Antioxidants; Ascorbic Acid; Blood Flow Velocity; Brachial Artery; Case-Control Studies; Endo | 2001 |
Association of maternal endothelial dysfunction with preeclampsia.
Topics: Adult; Antioxidants; Ascorbic Acid; Blood Flow Velocity; Brachial Artery; Case-Control Studies; Endo | 2001 |
Does nitric oxide play a role in the aetiology of pre-eclampsia?
Topics: Adult; Blotting, Western; Cell Adhesion; Cell Line; Cell Movement; Enzyme Inhibitors; Female; Humans | 2001 |
Re: glyceryl trinitrate (GTN) patches are unsuitable in hypertensive pregnancy.
Topics: Administration, Cutaneous; Female; Headache; Humans; Nitroglycerin; Pre-Eclampsia; Pregnancy; Random | 2001 |
The hemodynamic effects of intubation during nitroglycerin infusion in severe preeclampsia.
Topics: Acute Disease; Adolescent; Adult; Anesthesia, General; Anesthesia, Obstetrical; Blood Volume; Drug E | 1991 |
Role of nitroglycerin ointment in preventing the pressure response during caesarean section in pre-eclampsia.
Topics: Cesarean Section; Female; Humans; Hypertension; Intubation, Intratracheal; Laryngoscopy; Nitroglycer | 1989 |
Role of intravenous nitroglycerin in the treatment of severe pregnancy-induced hypertension complicated by pulmonary edema.
Topics: Female; Hemodynamics; Humans; Infusions, Parenteral; Nitroglycerin; Oxygen Consumption; Pre-Eclampsi | 1986 |
Role of volume expansion in severe pre-eclampsia.
Topics: Antihypertensive Agents; Blood Pressure; Blood Volume; Cardiac Catheterization; Colloids; Delivery, | 1988 |
The use of nitroglycerin in preventing the hypertensive response to tracheal intubation in severe preeclampsia.
Topics: Adult; Cesarean Section; Drug Evaluation; Female; Fetus; Humans; Hypertension; Infant, Newborn; Infu | 1985 |