Page last updated: 2024-11-01

nitroglycerin and Placental Insufficiency

nitroglycerin has been researched along with Placental Insufficiency in 4 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Placental Insufficiency: Failure of the PLACENTA to deliver an adequate supply of nutrients and OXYGEN to the FETUS.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effect of transdermal nitroglycerin on Doppler velocity waveforms of the uterine, umbilical and fetal middle cerebral arteries in patients with severe pre-eclampsia."7.77Transdermal nitroglycerin in patients with severe pre-eclampsia with placental insufficiency: effect on uterine, umbilical and fetal middle cerebral artery resistance indices. ( Gonçalves, LF; Pires, MM; Trapani, A, 2011)
"To evaluate the effect of transdermal nitroglycerin on Doppler velocity waveforms of the uterine, umbilical and fetal middle cerebral arteries in patients with severe pre-eclampsia."3.77Transdermal nitroglycerin in patients with severe pre-eclampsia with placental insufficiency: effect on uterine, umbilical and fetal middle cerebral artery resistance indices. ( Gonçalves, LF; Pires, MM; Trapani, A, 2011)
"To our knowledge, this is the first time that a combination of aspirin and glyceryl trinitrate (GTN) has been used in the prophylaxis of preeclampsia and fetal growth retardation, and their use associated with not only Doppler screening of the uterine arteries but also regular Doppler follow-up of the fetal arterial and venous circulation."3.70A novel approach to the management of pregnancies complicated by uteroplacental insufficiency and previous stillbirth. ( Black, RS; Campbell, S; Lees, CC; Oyelese, KO, 1998)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Trapani, A2
Gonçalves, LF2
Trapani, TF1
Franco, MJ1
Galluzzo, RN1
Pires, MM2
Espinoza, J1
Espinoza, AF1
Oyelese, KO1
Black, RS1
Lees, CC1
Campbell, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Use of Sildenafil Citrate in Management of Mild Pre-eclampsia: A Randomized Controlled Trial[NCT03262961]Phase 2/Phase 380 participants (Anticipated)Interventional2016-09-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for nitroglycerin and Placental Insufficiency

ArticleYear
Comparison between transdermal nitroglycerin and sildenafil citrate in intrauterine growth restriction: effects on uterine, umbilical and fetal middle cerebral artery pulsatility indices.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2016, Volume: 48, Issue:1

    Topics: Administration, Cutaneous; Adult; Blood Flow Velocity; Double-Blind Method; Female; Fetal Growth Ret

2016

Other Studies

3 other studies available for nitroglycerin and Placental Insufficiency

ArticleYear
Transdermal nitroglycerin in patients with severe pre-eclampsia with placental insufficiency: effect on uterine, umbilical and fetal middle cerebral artery resistance indices.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2011, Volume: 38, Issue:4

    Topics: Adult; Blood Flow Velocity; Female; Gestational Age; Humans; Middle Cerebral Artery; Nitroglycerin;

2011
Pre-eclampsia: a maternal manifestation of a fetal adaptive response?
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2011, Volume: 38, Issue:4

    Topics: Blood Flow Velocity; Female; Humans; Middle Cerebral Artery; Nitroglycerin; Placental Insufficiency;

2011
A novel approach to the management of pregnancies complicated by uteroplacental insufficiency and previous stillbirth.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1998, Volume: 38, Issue:4

    Topics: Adult; Aspirin; Drug Therapy, Combination; Female; Fetal Death; Fetal Growth Retardation; Fetal Moni

1998