Page last updated: 2024-11-01

nitroglycerin and Phlebitis

nitroglycerin has been researched along with Phlebitis in 10 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Phlebitis: Inflammation of a vein, often a vein in the leg. Phlebitis associated with a blood clot is called (THROMBOPHLEBITIS).

Research Excerpts

ExcerptRelevanceReference
"This study was conducted to examine the effects of sesame oil and nitroglycerin ointment on the incidence of chemotherapy-induced phlebitis in patients with cancer."9.69Comparing the Effects of Sesame Oil vs. Nitroglycerin Ointment on the Incidence of Chemotherapy-Induced Phlebitis: A Single Blind Clinical Trial. ( Ehsanpor, A; Elahi, N; Maraghi, E; Molavynejad, S; Safikani Mohammadzadeh, N, 2023)
"The purpose of this study was to evaluate the beneficial effects of transdermal nitroglycerine (TNG) in the treatment of superficial phlebitis caused by endovenous catheters and to compare them with the effects from the application of heparinoid substances."9.07[Heparinoids versus nitroglycerin in the treatment of superficial phlebitis]. ( Algarra, F; Almenar, L; Gimeno, JV; Hernández, M; Palencia, M, 1993)
"To evaluate the clinical use of transdermal nitroglycerin for the prevention of intravenous infusion failures due to phlebitis or extravasation."8.80Transdermal nitroglycerin for the prevention of intravenous infusion failure due to phlebitis and extravasation. ( Ansani, NT; Tjon, JA, 2000)
"This study was conducted to examine the effects of sesame oil and nitroglycerin ointment on the incidence of chemotherapy-induced phlebitis in patients with cancer."5.69Comparing the Effects of Sesame Oil vs. Nitroglycerin Ointment on the Incidence of Chemotherapy-Induced Phlebitis: A Single Blind Clinical Trial. ( Ehsanpor, A; Elahi, N; Maraghi, E; Molavynejad, S; Safikani Mohammadzadeh, N, 2023)
"The purpose of this study was to evaluate the beneficial effects of transdermal nitroglycerine (TNG) in the treatment of superficial phlebitis caused by endovenous catheters and to compare them with the effects from the application of heparinoid substances."5.07[Heparinoids versus nitroglycerin in the treatment of superficial phlebitis]. ( Algarra, F; Almenar, L; Gimeno, JV; Hernández, M; Palencia, M, 1993)
"To evaluate the clinical use of transdermal nitroglycerin for the prevention of intravenous infusion failures due to phlebitis or extravasation."4.80Transdermal nitroglycerin for the prevention of intravenous infusion failure due to phlebitis and extravasation. ( Ansani, NT; Tjon, JA, 2000)
"Phlebitis is the commonest complication of intravenous infusion."2.71Effect of transdermal glyceryl trinitrate and anti-inflammatory gel in infusion phlebitis. ( Cökmez, A; Deniz, S; Genç, H; Gür, S; Tarcan, E, 2003)
"Headaches were more common in patients with active patches but were relieved by simple analgesics."2.66Use of transdermal glyceryl trinitrate to reduce failure of intravenous infusion due to phlebitis and extravasation. ( Hecker, JF; Lewis, GB; Wright, A, 1985)
"Phlebitis is the commonest complication of intravenous infusion."2.66Effect of transdermal glyceryl trinitrate on the survival of peripheral intravenous infusions: a double-blind prospective clinical study. ( Campbell, MJ; Khawaja, HT; Weaver, PC, 1988)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's3 (30.00)18.2507
2000's3 (30.00)29.6817
2010's0 (0.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Safikani Mohammadzadeh, N1
Elahi, N1
Molavynejad, S1
Maraghi, E1
Ehsanpor, A1
Cökmez, A1
Gür, S1
Genç, H1
Deniz, S1
Tarcan, E1
Ruiz Trillo, C1
Borrero Esteban, MP1
Almenar, L1
Hernández, M1
Gimeno, JV1
Palencia, M1
Algarra, F1
Tjon, JA1
Ansani, NT1
Khawaja, HT4
Williams, JD1
Weaver, PC3
O'Brien, BJ2
Buxton, MJ2
Wright, A1
Hecker, JF1
Lewis, GB1
Campbell, MJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
To Investigate the Effectiveness of Topical Glycerine Sulphate, Hirudoid Cream and Nil Application in Treating Peripheral Cannula Related Phlebitis[NCT01226069]147 participants (Actual)Interventional2009-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nitroglycerin and Phlebitis

ArticleYear
Transdermal nitroglycerin for the prevention of intravenous infusion failure due to phlebitis and extravasation.
    The Annals of pharmacotherapy, 2000, Volume: 34, Issue:10

    Topics: Administration, Cutaneous; Capillary Permeability; Humans; Infusions, Intravenous; Nitroglycerin; Ph

2000

Trials

7 trials available for nitroglycerin and Phlebitis

ArticleYear
Comparing the Effects of Sesame Oil vs. Nitroglycerin Ointment on the Incidence of Chemotherapy-Induced Phlebitis: A Single Blind Clinical Trial.
    Asian Pacific journal of cancer prevention : APJCP, 2023, Apr-01, Volume: 24, Issue:4

    Topics: Administration, Topical; Antineoplastic Agents; Humans; Incidence; Nitroglycerin; Ointments; Phlebit

2023
Effect of transdermal glyceryl trinitrate and anti-inflammatory gel in infusion phlebitis.
    ANZ journal of surgery, 2003, Volume: 73, Issue:10

    Topics: Administration, Cutaneous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Gels; Humans; Inf

2003
[Heparinoids versus nitroglycerin in the treatment of superficial phlebitis].
    Revista clinica espanola, 1993, Volume: 193, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Catheterization, Peripheral; Female; Heparin; Humans; Male; Middle A

1993
Transdermal glyceryl trinitrate to allow peripheral total parenteral nutrition: a double-blind placebo controlled feasibility study.
    Journal of the Royal Society of Medicine, 1991, Volume: 84, Issue:2

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Feasibil

1991
An economic evaluation of transdermal glyceryl trinitrate in the prevention of intravenous infusion failure.
    Journal of clinical epidemiology, 1990, Volume: 43, Issue:8

    Topics: Administration, Cutaneous; Cost-Benefit Analysis; Double-Blind Method; Extravasation of Diagnostic a

1990
Use of transdermal glyceryl trinitrate to reduce failure of intravenous infusion due to phlebitis and extravasation.
    Lancet (London, England), 1985, Nov-23, Volume: 2, Issue:8465

    Topics: Administration, Topical; Clinical Trials as Topic; Double-Blind Method; Extravasation of Diagnostic

1985
Effect of transdermal glyceryl trinitrate on the survival of peripheral intravenous infusions: a double-blind prospective clinical study.
    The British journal of surgery, 1988, Volume: 75, Issue:12

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Catheterization, Peripheral; Clinical Trials as

1988

Other Studies

2 other studies available for nitroglycerin and Phlebitis

ArticleYear
[Treatment applied to post-perfusion phlebitis].
    Revista de enfermeria (Barcelona, Spain), 2006, Volume: 29, Issue:2

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Female; Humans; Injections, Intravenous; Male; M

2006
Cost minimisation study of transdermal glyceryl trinitrate in reducing failures of peripheral intravenous infusion.
    BMJ (Clinical research ed.), 1989, Jul-08, Volume: 299, Issue:6691

    Topics: Administration, Cutaneous; Cost Control; England; Hospitalization; Humans; Infusions, Intravenous; N

1989