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nitroglycerin and Persistent Fetal Circulation Syndrome

nitroglycerin has been researched along with Persistent Fetal Circulation Syndrome in 4 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Persistent Fetal Circulation Syndrome: A syndrome of persistent PULMONARY HYPERTENSION in the newborn infant (INFANT, NEWBORN) without demonstrable HEART DISEASES. This neonatal condition can be caused by severe pulmonary vasoconstriction (reactive type), hypertrophy of pulmonary arterial muscle (hypertrophic type), or abnormally developed pulmonary arterioles (hypoplastic type). The newborn patient exhibits CYANOSIS and ACIDOSIS due to the persistence of fetal circulatory pattern of right-to-left shunting of blood through a patent ductus arteriosus (DUCTUS ARTERIOSUS, PATENT) and at times a patent foramen ovale (FORAMEN OVALE, PATENT).

Research Excerpts

ExcerptRelevanceReference
"(1) Continuous intravenous infusion (2-10 micrograms/kg/min) of nitroglycerin (TNG) was administered to 20 neonates consisting of 17 with refractory congestive heart failure and 3 with PFC (Persistent Fetal Circulation)."9.06Effects of intravenous nitroglycerin on hemodynamics in neonates with refractory congestive heart failure or PFC. ( Kawano, T; Tamura, M, 1990)
"Pulmonary hypertension was induced by an iv infusion of group B Streptococci."5.27Neither nitroglycerin nor nitroprusside selectively reduces sepsis-induced pulmonary hypertension in piglets. ( Komar, KJ; Meadow, WL; Rudinsky, BF; Strates, E, 1987)
"(1) Continuous intravenous infusion (2-10 micrograms/kg/min) of nitroglycerin (TNG) was administered to 20 neonates consisting of 17 with refractory congestive heart failure and 3 with PFC (Persistent Fetal Circulation)."5.06Effects of intravenous nitroglycerin on hemodynamics in neonates with refractory congestive heart failure or PFC. ( Kawano, T; Tamura, M, 1990)
"Pulmonary hypertension was induced by an iv infusion of group B Streptococci."1.27Neither nitroglycerin nor nitroprusside selectively reduces sepsis-induced pulmonary hypertension in piglets. ( Komar, KJ; Meadow, WL; Rudinsky, BF; Strates, E, 1987)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iijima, S1
Ueno, D1
Baba, T1
Ohishi, A1
Drummond, WH1
Tamura, M1
Kawano, T1
Rudinsky, BF1
Komar, KJ1
Strates, E1
Meadow, WL1

Reviews

2 reviews available for nitroglycerin and Persistent Fetal Circulation Syndrome

ArticleYear
Hypertrophic pyloric stenosis following persistent pulmonary hypertension of the newborn: a case report and literature review.
    BMC pediatrics, 2018, 09-03, Volume: 18, Issue:1

    Topics: Antihypertensive Agents; Atropine; Bosentan; Bronchodilator Agents; Female; High-Frequency Ventilati

2018
Persistent pulmonary hypertension of the neonate (persistent fetal circulation syndrome).
    Advances in pediatrics, 1983, Volume: 30

    Topics: Acetylcholine; Calcium; Catecholamines; Epoprostenol; Homeostasis; Humans; Hypertension, Pulmonary;

1983

Trials

1 trial available for nitroglycerin and Persistent Fetal Circulation Syndrome

ArticleYear
Effects of intravenous nitroglycerin on hemodynamics in neonates with refractory congestive heart failure or PFC.
    Acta paediatrica Japonica : Overseas edition, 1990, Volume: 32, Issue:3

    Topics: Female; Heart Failure; Hemodynamics; Humans; Infant, Newborn; Infusions, Intravenous; Male; Nitrogly

1990

Other Studies

1 other study available for nitroglycerin and Persistent Fetal Circulation Syndrome

ArticleYear
Neither nitroglycerin nor nitroprusside selectively reduces sepsis-induced pulmonary hypertension in piglets.
    Critical care medicine, 1987, Volume: 15, Issue:12

    Topics: Animals; Aorta; Blood Pressure; Disease Models, Animal; Drug Evaluation, Preclinical; Ferricyanides;

1987