nitroglycerin has been researched along with Peripheral Arterial Diseases in 9 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We examined whether NMD is impaired in obesity by performing a GTN dose-response study, as this is a potentially more sensitive measure of arterial smooth muscle function." | 2.76 | Severe obesity is associated with impaired arterial smooth muscle function in young adults. ( Ayer, JG; Celermajer, DS; David, C; Harmer, JA; S Steinbeck, K; Seale, JP, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Nordanstig, J | 1 |
| Langenskiöld, M | 1 |
| Lawall, H | 1 |
| Bramlage, P | 1 |
| Gorath, M | 1 |
| Wittig, T | 1 |
| Kiani, S | 1 |
| Aasen, JG | 1 |
| Holbrook, M | 1 |
| Khemka, A | 1 |
| Sharmeen, F | 1 |
| LeLeiko, RM | 1 |
| Tabit, CE | 1 |
| Farber, A | 1 |
| Eberhardt, RT | 1 |
| Gokce, N | 1 |
| Vita, JA | 1 |
| Hamburg, NM | 1 |
| Kashyap, VS | 1 |
| Lakin, RO | 1 |
| Feiten, LE | 1 |
| Bishop, PD | 1 |
| Sarac, TP | 1 |
| Kajikawa, M | 2 |
| Maruhashi, T | 2 |
| Iwamoto, Y | 2 |
| Iwamoto, A | 2 |
| Matsumoto, T | 2 |
| Hidaka, T | 1 |
| Kihara, Y | 2 |
| Chayama, K | 2 |
| Nakashima, A | 2 |
| Goto, C | 2 |
| Noma, K | 2 |
| Higashi, Y | 2 |
| Oda, N | 1 |
| Ayer, JG | 1 |
| Harmer, JA | 1 |
| David, C | 1 |
| S Steinbeck, K | 1 |
| Seale, JP | 1 |
| Celermajer, DS | 1 |
| Banerjee, S | 1 |
| Badhey, N | 1 |
| Lichtenwalter, C | 1 |
| Varghese, C | 1 |
| Brilakis, ES | 1 |
| HUEBER, EF | 1 |
| THALER, H | 1 |
| WICK, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Endothelial Function in Human Arteries[NCT00848302] | Early Phase 1 | 25 participants (Actual) | Interventional | 2009-09-30 | Completed | ||
| Outcomes in Femoropopliteal Disease Stratified by Translesional Pressure Gradient[NCT02387658] | 25 participants (Actual) | Observational | 2015-02-06 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for nitroglycerin and Peripheral Arterial Diseases
| Article | Year |
|---|---|
Intermittent Administration of Nitroglycerin Sublingual Powder Compared with Placebo in Outpatients with Peripheral Artery Disease: Results of a Randomised Proof of Concept Study.
Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Ambulatory Care; Double-Blind Method; Dr | 2021 |
Severe obesity is associated with impaired arterial smooth muscle function in young adults.
Topics: Adolescent; Adult; Blood Flow Velocity; Blood Pressure; Body Mass Index; Brachial Artery; Female; Hu | 2011 |
7 other studies available for nitroglycerin and Peripheral Arterial Diseases
| Article | Year |
|---|---|
Are These Pills Made for Walking?
Topics: Humans; Nitroglycerin; Outpatients; Peripheral Arterial Disease; Powders; Proof of Concept Study; Wa | 2021 |
Peripheral artery disease is associated with severe impairment of vascular function.
Topics: Aged; Blood Flow Velocity; Blood Vessels; Brachial Artery; Comorbidity; Coronary Artery Disease; End | 2013 |
In vivo assessment of endothelial function in human lower extremity arteries.
Topics: Acetylcholine; Aged; Biomarkers; Endothelium, Vascular; Endovascular Procedures; Female; Femoral Art | 2013 |
Borderline ankle-brachial index value of 0.91-0.99 is associated with endothelial dysfunction.
Topics: Adult; Aged; Ankle Brachial Index; Female; Humans; Male; Middle Aged; Nitroglycerin; Peripheral Arte | 2014 |
Relationship between nitroglycerine-induced vasodilation and clinical severity of peripheral artery disease.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Case-Control Studies; Endothelium, Vascular; Female; | 2014 |
Relationship of walking impairment and ankle-brachial index assessments with peripheral arterial translesional pressure gradients.
Topics: Adenosine; Ankle Brachial Index; Blood Pressure; Female; Gait Ataxia; Health Status Indicators; Huma | 2011 |
[Peripheral arterial circulatory disorders and therapy. I. Rheoangiographic registration of the effect of nitroglycerin preparations in healthy subjects].
Topics: Healthy Volunteers; Nitrites; Nitroglycerin; Peripheral Arterial Disease; Peripheral Vascular Diseas | 1956 |