nitroglycerin has been researched along with Osteoporosis in 7 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The preventive effects of nitroglycerine (NG) on glucocorticoid-induced osteoporosis in growing rats were studied." | 7.74 | Preventive effects of nitroglycerine on glucocorticoid-induced osteoporosis in growing rats. ( Li, Y; Yang, W, 2007) |
| "Depression, osteoporosis, and the use of enalapril were associated with a higher risk of dementia, while nitroglycerin might be a protecting factor for dementia, in subjects with cerebrovascular diseases without mention of cerebral infarction." | 4.31 | Risk Factors of Dementia in Patients with Cerebral Vascular Diseases Based on Taiwan National Health Insurance Data. ( Fukushima, M; Hsu, CY; Kojima, S; Lin, CL; Zhou, B, 2023) |
| "The preventive effects of nitroglycerine (NG) on glucocorticoid-induced osteoporosis in growing rats were studied." | 3.74 | Preventive effects of nitroglycerine on glucocorticoid-induced osteoporosis in growing rats. ( Li, Y; Yang, W, 2007) |
| "Nitroglycerine has beneficial effects in multiple systems, especially the cardiovascular system." | 2.44 | Rationale for using nitric oxide donor therapy for prevention of bone loss and treatment of osteoporosis in humans. ( Wimalawansa, SJ, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, B | 1 |
| Lin, CL | 1 |
| Kojima, S | 1 |
| Fukushima, M | 1 |
| Hsu, CY | 1 |
| Khosla, S | 1 |
| Hao, YJ | 1 |
| Tang, Y | 1 |
| Chen, FB | 1 |
| Pei, FX | 1 |
| Wimalawansa, SJ | 2 |
| Li, Y | 2 |
| Yang, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Influence of Nitrates on Bone Remodeling and Endothelial Function in Patients With Type 2 Diabetes Mellitus.[NCT02011620] | Phase 4 | 0 participants (Actual) | Interventional | 2014-10-31 | Withdrawn (stopped due to The sponsor was no longer in a position to sponsor a CTIMP. Study did not open.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nitroglycerin and Osteoporosis
| Article | Year |
|---|---|
Rationale for using nitric oxide donor therapy for prevention of bone loss and treatment of osteoporosis in humans.
Topics: Animals; Bone and Bones; Bone Density; Clinical Trials as Topic; Cyclic GMP; Estrogens; Female; Huma | 2007 |
6 other studies available for nitroglycerin and Osteoporosis
| Article | Year |
|---|---|
Risk Factors of Dementia in Patients with Cerebral Vascular Diseases Based on Taiwan National Health Insurance Data.
Topics: Cerebral Infarction; Cerebrovascular Disorders; Dementia; Enalapril; Humans; Nitroglycerin; Osteopor | 2023 |
Is nitroglycerin a novel and inexpensive treatment for osteoporosis?
Topics: Animals; Bone Density; Bone Density Conservation Agents; Bone Resorption; Female; Fractures, Bone; H | 2011 |
New bone density treatment is a tried-and-true heart medication. The cost, efficacy and ease of administering nitroglycerin could mean a game-changer for treating thinning bones.
Topics: Bone Density; Bone Density Conservation Agents; Female; Humans; Middle Aged; Nitroglycerin; Osteopor | 2011 |
Different doses of nitric oxide donor prevent osteoporosis in ovariectomized rats.
Topics: Analysis of Variance; Animals; Bone Density; Estradiol; Female; Nitric Oxide Donors; Nitroglycerin; | 2005 |
Preventive effects of nitroglycerine on glucocorticoid-induced osteoporosis in growing rats.
Topics: Animals; Bone Density; Dexamethasone; Female; Nitric Oxide Donors; Nitroglycerin; Osteoporosis; Rand | 2007 |
Restoration of ovariectomy-induced osteopenia by nitroglycerin.
Topics: Absorptiometry, Photon; Amino Acids; Animals; Body Weight; Bone Density; Drug Therapy, Combination; | 2000 |