nitroglycerin has been researched along with Optic Nerve Diseases in 2 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Optic Nerve Diseases: Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effects of nitroglycerin on the eye and specifically on intraocular pressure has been investigated with diverse results." | 3.70 | Nitrate therapy may retard glaucomatous optic neuropathy, perhaps through modulation of glutamate receptors. ( Chaturvedi, N; Dreyer, EB; Gorla, M; Grosskreutz, CL; Kanellopoulos, AJ; Lipton, SA; Vorwerk, CK; Zurakowski, D, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Acharya, S | 1 |
| Rogers, P | 1 |
| Krishnamoorthy, RR | 1 |
| Stankowska, DL | 1 |
| Dias, HV | 1 |
| Yorio, T | 1 |
| Zurakowski, D | 1 |
| Vorwerk, CK | 1 |
| Gorla, M | 1 |
| Kanellopoulos, AJ | 1 |
| Chaturvedi, N | 1 |
| Grosskreutz, CL | 1 |
| Lipton, SA | 1 |
| Dreyer, EB | 1 |
2 other studies available for nitroglycerin and Optic Nerve Diseases
| Article | Year |
|---|---|
Design and synthesis of novel hybrid sydnonimine and prodrug useful for glaucomatous optic neuropathy.
Topics: Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Glaucoma; Humans; Hydrogen | 2016 |
Nitrate therapy may retard glaucomatous optic neuropathy, perhaps through modulation of glutamate receptors.
Topics: Aged; Aged, 80 and over; Comorbidity; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ma | 1998 |