Page last updated: 2024-11-01

nitroglycerin and Necrosis

nitroglycerin has been researched along with Necrosis in 61 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"There was an overall 22 percent decreased incidence of mastectomy flap necrosis in the nitroglycerin ointment cohort (47."9.27Nitroglycerin Ointment for Reducing the Rate of Mastectomy Flap Necrosis in Immediate Implant-Based Breast Reconstruction. ( Fine, N; Li, DD; Turin, SY; Vaca, EE, 2018)
"In patients undergoing mastectomy and immediate reconstruction, there was a marked reduction in mastectomy flap necrosis in patients who received nitroglycerin ointment."9.20Effects of nitroglycerin ointment on mastectomy flap necrosis in immediate breast reconstruction: a randomized controlled trial. ( Bahng, S; Bovill, E; Brasher, P; Gdalevitch, P; Ho, A; Lennox, P; Macadam, S; Van Laeken, N, 2015)
"To study effects of long-term morphine-clofelin epidural analgesia and infusion of nitroglycerin on formation of the necrosis focus and the clinical course of acute myocardial infarction (MI)."9.11[Effect of long-term epidural analgesia and nitroglycerin infusion on formation of necrosis zone and clinical course of myocardial infarction]. ( Dzizinskiĭ, AA; Tumak, VN, 2004)
"Routine use of intravenous nitroglycerin after coronary stenting significantly reduced the occurrence of minor myocardial necrosis."9.09A double-blind, randomized study of the effect of immediate intravenous nitroglycerin on the incidence of postprocedural chest pain and minor myocardial necrosis after elective coronary stenting. ( Bertel, O; Kurz, DJ; Naegeli, B, 2000)
" A prospective clinical trial of nitroglycerin was performed in 40 children undergoing hypospadias repair."9.06Effect of nitroglycerin ointment on penile skin flap survival in hypospadias repair. Experimental and clinical studies. ( Hanna, MK; Scheuer, S, 1986)
"Flap necrosis is a common complication after mastectomy, and nitroglycerin (NTG) ointment has been used successfully to treat it."9.05Efficacy and safety of topical nitroglycerin in the prevention of mastectomy flap necrosis: a systematic review and meta-analysis. ( Gu, L; Ma, J; Qin, Z; Wang, P; Wang, Q, 2020)
"Dermal necrosis is a rare yet serious risk associated with cosmetic filler injections, and although current consensus recommends the use of hyaluronidase injections in cases of hyaluronic acid filler, the efficacy of topical nitroglycerin as a treatment has not yet been fully investigated."9.05Nitroglycerin, or Not, When Treating Impending Filler Necrosis. ( Carley, SK; Cohen, JL; Kraus, CN, 2020)
"We modified nitric oxide levels in rabbits using L-NAME (a NO synthase blocker) or nitroglycerine (a NO donor), and simultaneously evaluated variations in total and HDL cholesterol levels, some coagulation parameters, mean blood pressure values and myocardial necrosis patterns."7.72Drugs modifying nitric oxide metabolism affect plasma cholesterol levels, coagulation parameters, blood pressure values and the appearance of plasma myocardial necrosis markers in rabbits: opposite effects of L-NAME and nitroglycerine. ( Accinni, R; Bertolini, B; Bonacina, E; Brenna, S; Pinelli, A; Tomasoni, L; Trivulzio, S, 2003)
" In this communication, we elucidate the effect of exogenous NO administration, using nitroglycerin (GTN), on ferric nitrilotriacetate (Fe-NTA)-induced renal oxidative stress, hyperproliferative response and necrosis in ddY mice."7.72Nitroglycerin, a nitric oxide generator attenuates ferric nitrilotriacetate-induced renal oxidative stress, hyperproliferative response and necrosis in ddY mice. ( Iqbal, M; Okada, S; Okazaki, Y; Sharma, SD, 2003)
"In experiments on 150 rabbits with experimental necrosis of the myocardium it was shown that intravenous administration of nitroglycerin leads to decrease of morphological dimensions of the lesion and to positive dynamics of the precardial chartogram."7.66[Effect of nitroglycerin on the dimensions of the focal lesion in experimental myocardial necrosis]. ( Afonskaia, NI; Cherpachenko, NM; Kaverina, NV; Ostrogorskiĭ, IuM; Rozonov, IuB, 1982)
"Nitroglycerin seemed to be an ideal agent to increase the chance of flap survival in mastectomy flaps."6.66Topical nitroglycerin is associated with a reduced mastectomy skin flap necrosis-systematic review and meta-analysis. ( Irwansyah, D; Pranata, R; Vania, R, 2020)
"There was an overall 22 percent decreased incidence of mastectomy flap necrosis in the nitroglycerin ointment cohort (47."5.27Nitroglycerin Ointment for Reducing the Rate of Mastectomy Flap Necrosis in Immediate Implant-Based Breast Reconstruction. ( Fine, N; Li, DD; Turin, SY; Vaca, EE, 2018)
"Nitroglycerin has a reducing influence on these changes, but not down to the initial level."5.26[The treatment of acute myocardial infarctions with beta-receptor-blockers. II. Hemodynamic effects of propranolol with and without combination therapy with nitroglycerin (author's transl)]. ( Hochrein, H; Lehmann, HU; Oeff, M; Witt, E, 1981)
"Nitroglycerin was injected intravenously (100 micrograms/min) from 120 to 180 minutes after the operation."5.26[Effect of nitroglycerin on the extent of experimental myocardial necrosis]. ( Afonskaia, NI; Cherpachenko, NM; Kaverina, NV; Ostrogorskiĭ, IuM; Rozonov, IuB, 1981)
"In patients undergoing mastectomy and immediate reconstruction, there was a marked reduction in mastectomy flap necrosis in patients who received nitroglycerin ointment."5.20Effects of nitroglycerin ointment on mastectomy flap necrosis in immediate breast reconstruction: a randomized controlled trial. ( Bahng, S; Bovill, E; Brasher, P; Gdalevitch, P; Ho, A; Lennox, P; Macadam, S; Van Laeken, N, 2015)
"To study effects of long-term morphine-clofelin epidural analgesia and infusion of nitroglycerin on formation of the necrosis focus and the clinical course of acute myocardial infarction (MI)."5.11[Effect of long-term epidural analgesia and nitroglycerin infusion on formation of necrosis zone and clinical course of myocardial infarction]. ( Dzizinskiĭ, AA; Tumak, VN, 2004)
"Routine use of intravenous nitroglycerin after coronary stenting significantly reduced the occurrence of minor myocardial necrosis."5.09A double-blind, randomized study of the effect of immediate intravenous nitroglycerin on the incidence of postprocedural chest pain and minor myocardial necrosis after elective coronary stenting. ( Bertel, O; Kurz, DJ; Naegeli, B, 2000)
" A prospective clinical trial of nitroglycerin was performed in 40 children undergoing hypospadias repair."5.06Effect of nitroglycerin ointment on penile skin flap survival in hypospadias repair. Experimental and clinical studies. ( Hanna, MK; Scheuer, S, 1986)
"Flap necrosis is a common complication after mastectomy, and nitroglycerin (NTG) ointment has been used successfully to treat it."5.05Efficacy and safety of topical nitroglycerin in the prevention of mastectomy flap necrosis: a systematic review and meta-analysis. ( Gu, L; Ma, J; Qin, Z; Wang, P; Wang, Q, 2020)
" Nitroglycerin paste may be an important treatment option for dermal and epidermal ischemia in cosmetic surgery."4.88Nitroglycerin: a review of its use in the treatment of vascular occlusion after soft tissue augmentation. ( Cohen, JL; Kleydman, K; Marmur, E, 2012)
"We describe a protocol utilizing hyaluronidase, nitroglycerin paste, aspirin, antacid and a topical oxygen therapy that may be used to treat impending necrosis subsequent to injection with soft tissue fillers."3.77Management of impending necrosis associated with soft tissue filler injections. ( Arkins, JP; Dayan, SH; Mathison, CC, 2011)
" In this communication, we elucidate the effect of exogenous NO administration, using nitroglycerin (GTN), on ferric nitrilotriacetate (Fe-NTA)-induced renal oxidative stress, hyperproliferative response and necrosis in ddY mice."3.72Nitroglycerin, a nitric oxide generator attenuates ferric nitrilotriacetate-induced renal oxidative stress, hyperproliferative response and necrosis in ddY mice. ( Iqbal, M; Okada, S; Okazaki, Y; Sharma, SD, 2003)
"We modified nitric oxide levels in rabbits using L-NAME (a NO synthase blocker) or nitroglycerine (a NO donor), and simultaneously evaluated variations in total and HDL cholesterol levels, some coagulation parameters, mean blood pressure values and myocardial necrosis patterns."3.72Drugs modifying nitric oxide metabolism affect plasma cholesterol levels, coagulation parameters, blood pressure values and the appearance of plasma myocardial necrosis markers in rabbits: opposite effects of L-NAME and nitroglycerine. ( Accinni, R; Bertolini, B; Bonacina, E; Brenna, S; Pinelli, A; Tomasoni, L; Trivulzio, S, 2003)
"Topical nitroglycerin has been reported to prevent skin necrosis from brown recluse spider bites, but this has never been scientifically tested."3.71A controlled trial of topical nitroglycerin in a New Zealand white rabbit model of brown recluse spider envenomation. ( Bradfield, JF; Brewer, K; Carroll, RG; Lowry, BP; Meggs, WJ, 2001)
"To assess whether the reduction in ischaemic injury during acute myocardial infarction induced by nitroglycerin (NTG) results in a decrease in tissue necrosis, 96 rats were assigned to two groups."3.67Long-term protection of ischaemic myocardium by nitroglycerin ointment. ( Ambrosio, G; Brevetti, G; Cataffo, A; Chiariello, M; Condorelli, M; Pollice, U, 1984)
"In experiments on 150 rabbits with experimental necrosis of the myocardium it was shown that intravenous administration of nitroglycerin leads to decrease of morphological dimensions of the lesion and to positive dynamics of the precardial chartogram."3.66[Effect of nitroglycerin on the dimensions of the focal lesion in experimental myocardial necrosis]. ( Afonskaia, NI; Cherpachenko, NM; Kaverina, NV; Ostrogorskiĭ, IuM; Rozonov, IuB, 1982)
"Injection necrosis is a rare but clinically important potential complication caused by interruption of the vascular supply to the area by compression, injury, and/or obstruction of the vessel(s)."2.43Injection necrosis of the glabella: protocol for prevention and treatment after use of dermal fillers. ( Cohen, JL; Glaich, AS; Goldberg, LH, 2006)
"With venous congestion, nitroglycerin and BoTA treatments mitigated the epidermal and dermal injury; and clopidogrel caused coagulative necrosis."1.72Experimental study of the effects of nitroglycerin, botulinum toxin A, and clopidogrel on bipedicled superficial inferior epigastric artery flap survival. ( Abdel Fattah, IO; Abdel Kader, G; Abdelrahman, I; Ellabban, MA; Elmasry, M; Gomaa, AA; Sjoberg, F; Steinvall, I, 2022)
"Tissue necrosis was greatest in controls (51."1.62Quantifying the Effect of Topical Nitroglycerin on Random Pattern Flap Perfusion in a Rodent Model: An Application of the ViOptix Intra.Ox for Dynamic Flap Perfusion Assessment and Salvage. ( Darrach, H; Khavanin, N; Kraenzlin, F; Sacks, JM; Yesantharao, P, 2021)
"Injection-induced necrosis is a rare but dreaded consequence of soft tissue augmentation with filler agents."1.42Treatment of Hyaluronic Acid Filler-Induced Impending Necrosis With Hyaluronidase: Consensus Recommendations. ( Biesman, BS; Cohen, JL; Dayan, SH; DeLorenzi, C; Lambros, VS; Nestor, MS; Sadick, N; Sykes, J, 2015)
"Injection necrosis is a rare but clinically significant side effect."1.34Delayed presentation of impending necrosis following soft tissue augmentation with hyaluronic acid and successful management with hyaluronidase. ( Cohen, JL; Duffy, D; Hirsch, RJ; Lupo, M, 2007)
"Flap necrosis is still a significant complication in all types of flap surgery."1.30Effect of parenteral pentoxifylline and topical nitroglycerin on skin flap survival. ( Akbaş, H; Karacaoğlan, N, 1999)
"This study used an animal model of acute pancreatitis induced by intravenous caeruleint (10 micrograms/kg/h for up to six hours), which does not entail either haemorrhage or significant necrosis of the pancreas."1.29Vasoactive mediators and the progression from oedematous to necrotising experimental acute pancreatitis. ( Adler, G; Gress, TM; Lerch, MM; Pfaff, D; Turi, S; Weidenbach, H, 1995)
"Nitroglycerin was injected intravenously (100 micrograms/min) from 120 to 180 minutes after the operation."1.26[Effect of nitroglycerin on the extent of experimental myocardial necrosis]. ( Afonskaia, NI; Cherpachenko, NM; Kaverina, NV; Ostrogorskiĭ, IuM; Rozonov, IuB, 1981)
"Nitroglycerin has a reducing influence on these changes, but not down to the initial level."1.26[The treatment of acute myocardial infarctions with beta-receptor-blockers. II. Hemodynamic effects of propranolol with and without combination therapy with nitroglycerin (author's transl)]. ( Hochrein, H; Lehmann, HU; Oeff, M; Witt, E, 1981)

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-199023 (37.70)18.7374
1990's9 (14.75)18.2507
2000's10 (16.39)29.6817
2010's11 (18.03)24.3611
2020's8 (13.11)2.80

Authors

AuthorsStudies
Ellabban, MA3
Elmasry, M3
Abdelrahman, I3
Abdel Kader, G3
Steinvall, I3
Sjoberg, F3
Gomaa, AA3
Abdel Fattah, IO3
Yao, A1
Greige, N1
Ricci, JA2
Draper, LB1
Weichman, KE1
Parra-Marquez, ML1
Peralta-Enriquez, A1
Peña, VG1
Charles-Lozoya, S1
Kerolus, JL1
Nassif, PS1
Vania, R1
Pranata, R1
Irwansyah, D1
Egger, A1
Tosti, A1
Wang, P1
Gu, L1
Qin, Z1
Wang, Q1
Ma, J1
Khavanin, N1
Yesantharao, P1
Kraenzlin, F1
Darrach, H1
Sacks, JM1
Singhal, D1
Fukudome, EY1
Tobias, AM1
Lin, SJ1
Lee, BT1
Turin, SY1
Li, DD1
Vaca, EE1
Fine, N1
Bibli, SI1
Papapetropoulos, A1
Iliodromitis, EK1
Daiber, A1
Randriamboavonjy, V1
Steven, S1
Brouckaert, P1
Chatzianastasiou, A1
Kypreos, KE1
Hausenloy, DJ1
Fleming, I1
Andreadou, I1
Carley, SK1
Kraus, CN1
Cohen, JL5
Biesman, BS1
Dayan, SH2
DeLorenzi, C1
Lambros, VS1
Nestor, MS1
Sadick, N1
Sykes, J1
Gdalevitch, P1
Van Laeken, N1
Bahng, S1
Ho, A1
Bovill, E1
Lennox, P1
Brasher, P1
Macadam, S1
Andersen, RJ1
Campoli, J1
Johar, SK1
Schumacher, KA1
Allison, EJ1
Kutun, S1
Ay, AA1
Ulucanlar, H1
Tarcan, O1
Ay, A1
Aldan, M1
Gorkem, G1
Demir, A1
Cetin, A1
Arkins, JP1
Mathison, CC1
Kleydman, K1
Marmur, E1
Kamar, R1
van Vonderen, JJ1
Lopriore, E1
Te Pas, AB1
Pinelli, A2
Trivulzio, S2
Tomasoni, L2
Bertolini, B2
Brenna, S2
Bonacina, E2
Atalay, C1
Koçkaya, EA1
Cetin, B1
Kismet, K1
Akay, MT1
Accinni, R1
Iqbal, M1
Okazaki, Y1
Sharma, SD1
Okada, S1
Ducasse, E1
Creusy, C1
Mazurier, J1
Cosset, JM1
Eschwege, F1
Puppinck, P1
Speziale, F1
Sbarigia, E1
Fiorani, P1
Lartigau, E1
Tumak, VN1
Dzizinskiĭ, AA1
Glaich, AS1
Goldberg, LH1
Hirsch, RJ1
Lupo, M1
Duffy, D1
Zharov, EI1
Sal'nikov, SN1
Vertkin, AL1
Taylor, RR1
Muller, JE1
Braunwald, E1
Shimoura, K1
Meerbaum, S1
Sakamaki, T1
Kondo, S1
Fishbein, MC1
Y-Rit, J1
Tei, C1
Shah, PM1
Corday, E1
Senoo, Y1
Murakami, T1
Kawakami, S1
Teramoto, S1
Rohrich, RJ1
Cherry, GW1
Spira, M1
Chiariello, M1
Brevetti, G1
Ambrosio, G1
Cataffo, A1
Pollice, U1
Condorelli, M1
Zingone, B1
Klugmann, S1
Benussi, B1
Pappalardo, A1
Camerini, F1
Branchini, B1
Gichka, SG1
Terzieva, L1
Ostrogorskiĭ, IuM2
Afonskaia, NI3
Cherpachenko, NM3
Rozonov, IuB2
Kaverina, NV2
Lehmann, HU1
Oeff, M1
Witt, E1
Hochrein, H1
Swan, HJ1
Shah, PK1
Rubin, S1
Weidenbach, H1
Lerch, MM1
Gress, TM1
Pfaff, D1
Turi, S1
Adler, G1
Fan, Z1
He, J1
Karacaoğlan, N1
Akbaş, H1
Ozzeybek, D1
Koca, U1
Elar, Z1
Olguner, M1
Hakgüder, G1
Kurz, DJ1
Naegeli, B1
Bertel, O1
Lowry, BP1
Bradfield, JF1
Carroll, RG1
Brewer, K1
Meggs, WJ1
Gajewska-Lipka, J1
Krotkiewski, A1
Faivre, G1
Groussin, P1
Pesch, C1
Chiche, P1
Derrida, JP1
Baligadoo, S1
Sal, R1
Bockeria, LA1
Kupatadze, NI1
Saprigin, DB1
Aslanidi, IP1
Chigogidze, NA1
Dyadyurko, AM1
Poplavskaya, LM1
Zhang, C1
Hsueh, W1
Shvilkin, AV1
Sadretdinov, SM1
Levitskiĭ, DO1
Ruda, MIa1
Vértesi, C1
Knopf, E1
Körmöczy, PS1
Irazuzta, J1
McManus, ML1
Grodecki, J1
O'Reilly, C1
McKay, FM1
Duffty, P1
Lloyd, DJ1
Scheuer, S1
Hanna, MK1
Vassanelli, C1
Menegatti, G1
Nidasio, GP1
Franceschini, L1
Cocco, C1
Rizzotti, P1
Smith, ER1
Guy, CR1
Eliot, RS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Nitroglycerin Ointment on Mastectomy Flap Necrosis[NCT01608880]154 participants (Actual)Interventional2012-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

14 reviews available for nitroglycerin and Necrosis

ArticleYear
Treatment Protocol for Compromised Nasal Skin.
    Facial plastic surgery clinics of North America, 2019, Volume: 27, Issue:4

    Topics: Administration, Cutaneous; Anti-Bacterial Agents; Humans; Hyperbaric Oxygenation; Leeching; Necrosis

2019
Topical nitroglycerin is associated with a reduced mastectomy skin flap necrosis-systematic review and meta-analysis.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2020, Volume: 73, Issue:6

    Topics: Administration, Cutaneous; Female; Humans; Mastectomy; Necrosis; Nitroglycerin; Skin Transplantation

2020
Carpal tunnel syndrome and associated nail changes: Review and examples from the author's practice.
    Journal of the American Academy of Dermatology, 2020, Volume: 83, Issue:6

    Topics: Administration, Topical; Carpal Tunnel Syndrome; Decompression, Surgical; Fingers; Glucocorticoids;

2020
Efficacy and safety of topical nitroglycerin in the prevention of mastectomy flap necrosis: a systematic review and meta-analysis.
    Scientific reports, 2020, 04-21, Volume: 10, Issue:1

    Topics: Breast Neoplasms; Female; Humans; Mammaplasty; Mammary Glands, Human; Mastectomy; Middle Aged; Necro

2020
Nitroglycerin, or Not, When Treating Impending Filler Necrosis.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2020, Volume: 46, Issue:1

    Topics: Administration, Topical; Adult; Cosmetic Techniques; Dermal Fillers; Humans; Hyaluronic Acid; Middle

2020
Suspected brown recluse envenomation: a case report and review of different treatment modalities.
    The Journal of emergency medicine, 2011, Volume: 41, Issue:2

    Topics: Aged; Anti-Infective Agents; Dapsone; Electroconvulsive Therapy; Humans; Hyperbaric Oxygenation; Mal

2011
Nitroglycerin: a review of its use in the treatment of vascular occlusion after soft tissue augmentation.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2012, Volume: 38, Issue:12

    Topics: Administration, Topical; Cosmetic Techniques; Dosage Forms; Humans; Ischemia; Necrosis; Nitroglyceri

2012
Injection necrosis of the glabella: protocol for prevention and treatment after use of dermal fillers.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2006, Volume: 32, Issue:2

    Topics: Biocompatible Materials; Cardiovascular Agents; Clinical Protocols; Enzyme Therapy; Forehead; Hepari

2006
Pathophysiology of myocardial ischaemia and the prevention of necrosis.
    Clinical and experimental pharmacology & physiology. Supplement, 1982, Volume: 6

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Disease; Coronary Vasospasm; Diastol

1982
Can infarct size be limited in patients with acute myocardial infarction?
    Cardiovascular clinics, 1983, Volume: 13, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Cardiotonic Agents; Coronary Artery

1983
[Venous use of nitroglycerin in acute myocardial infarct].
    Vutreshni bolesti, 1984, Volume: 23, Issue:6

    Topics: Blood Pressure; Coronary Circulation; Heart; Heart Rate; Hemodynamics; Humans; Infusions, Parenteral

1984
[The role of nitroglycerin in limiting the area of necrosis in myocardial infarction].
    Folia medica Cracoviensia, 1989, Volume: 30, Issue:1-2

    Topics: Humans; Myocardial Infarction; Myocardium; Necrosis; Nitroglycerin

1989
Acute myocardial infarction and muscle salvage: a potential role for pharmacological agents.
    Canadian journal of surgery. Journal canadien de chirurgie, 1974, Volume: 17, Issue:2

    Topics: Adenosine; Adrenergic alpha-Agonists; Animals; Assisted Circulation; Collateral Circulation; Coronar

1974
The pathophysiologic vulnerability of the subendocardium of the left ventricle.
    Advances in cardiology, 1973, Volume: 9

    Topics: Arrhythmias, Cardiac; Capillaries; Cardiomegaly; Coronary Disease; Coronary Vessels; Endocardium; He

1973

Trials

7 trials available for nitroglycerin and Necrosis

ArticleYear
Nitroglycerin Ointment for Reducing the Rate of Mastectomy Flap Necrosis in Immediate Implant-Based Breast Reconstruction.
    Plastic and reconstructive surgery, 2018, Volume: 142, Issue:3

    Topics: Administration, Cutaneous; Adult; Breast; Breast Implantation; Breast Neoplasms; Female; Follow-Up S

2018
Effects of nitroglycerin ointment on mastectomy flap necrosis in immediate breast reconstruction: a randomized controlled trial.
    Plastic and reconstructive surgery, 2015, Volume: 135, Issue:6

    Topics: Administration, Topical; Adult; Aged; Breast Neoplasms; British Columbia; Female; Follow-Up Studies;

2015
Is transdermal nitroglycerin application effective in preventing and healing flap ischaemia after modified radical mastectomy?
    South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie, 2010, Volume: 48, Issue:4

    Topics: Administration, Topical; Adult; Breast Neoplasms; Chi-Square Distribution; Female; Humans; Ischemia;

2010
[Effect of long-term epidural analgesia and nitroglycerin infusion on formation of necrosis zone and clinical course of myocardial infarction].
    Terapevticheskii arkhiv, 2004, Volume: 76, Issue:8

    Topics: Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Case-Control Studies; Clonidine;

2004
A double-blind, randomized study of the effect of immediate intravenous nitroglycerin on the incidence of postprocedural chest pain and minor myocardial necrosis after elective coronary stenting.
    American heart journal, 2000, Volume: 139, Issue:1 Pt 1

    Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Biomarkers; Coronary Angiography; Coronary Disease;

2000
[The treatment of recent myocardial infarction by prolonged infusion of trinitrin (author's transl)].
    La Nouvelle presse medicale, 1977, Dec-24, Volume: 6, Issue:44

    Topics: Aged; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Female; Heart Failure; Heart Rate; Hum

1977
Effect of nitroglycerin ointment on penile skin flap survival in hypospadias repair. Experimental and clinical studies.
    Urology, 1986, Volume: 27, Issue:5

    Topics: Animals; Child; Clinical Trials as Topic; Dogs; Fluorescein Angiography; Humans; Hypospadias; Male;

1986

Other Studies

40 other studies available for nitroglycerin and Necrosis

ArticleYear
Experimental study of the effects of nitroglycerin, botulinum toxin A, and clopidogrel on bipedicled superficial inferior epigastric artery flap survival.
    Scientific reports, 2022, 12-03, Volume: 12, Issue:1

    Topics: Animals; Botulinum Toxins, Type A; Clopidogrel; Epigastric Arteries; Hyperemia; Necrosis; Nitroglyce

2022
Experimental study of the effects of nitroglycerin, botulinum toxin A, and clopidogrel on bipedicled superficial inferior epigastric artery flap survival.
    Scientific reports, 2022, 12-03, Volume: 12, Issue:1

    Topics: Animals; Botulinum Toxins, Type A; Clopidogrel; Epigastric Arteries; Hyperemia; Necrosis; Nitroglyce

2022
Experimental study of the effects of nitroglycerin, botulinum toxin A, and clopidogrel on bipedicled superficial inferior epigastric artery flap survival.
    Scientific reports, 2022, 12-03, Volume: 12, Issue:1

    Topics: Animals; Botulinum Toxins, Type A; Clopidogrel; Epigastric Arteries; Hyperemia; Necrosis; Nitroglyce

2022
Experimental study of the effects of nitroglycerin, botulinum toxin A, and clopidogrel on bipedicled superficial inferior epigastric artery flap survival.
    Scientific reports, 2022, 12-03, Volume: 12, Issue:1

    Topics: Animals; Botulinum Toxins, Type A; Clopidogrel; Epigastric Arteries; Hyperemia; Necrosis; Nitroglyce

2022
Topical Nitroglycerin Ointment Reduces Mastectomy Flap Necrosis in Immediate Autologous Breast Reconstruction.
    Plastic and reconstructive surgery, 2023, 10-01, Volume: 152, Issue:4

    Topics: Breast Neoplasms; Female; Humans; Mammaplasty; Mastectomy; Necrosis; Nitroglycerin; Ointments; Posto

2023
Protective effect of nitroglycerin ointment and dimethyl sulfoxide on necrosis of skin flaps in rats.
    Cirugia y cirujanos, 2023, Volume: 91, Issue:5

    Topics: Animals; Dimethyl Sulfoxide; Male; Necrosis; Nitroglycerin; Ointments; Petrolatum; Rats; Rats, Wista

2023
Quantifying the Effect of Topical Nitroglycerin on Random Pattern Flap Perfusion in a Rodent Model: An Application of the ViOptix Intra.Ox for Dynamic Flap Perfusion Assessment and Salvage.
    Plastic and reconstructive surgery, 2021, Jul-01, Volume: 148, Issue:1

    Topics: Animals; Disease Models, Animal; Graft Survival; Humans; Necrosis; Nitroglycerin; Oxygen; Postoperat

2021
Topical nitroglycerin for the treatment of intraoperative microsurgical vasospasm.
    Microsurgery, 2018, Volume: 38, Issue:5

    Topics: Administration, Topical; Adult; Anastomosis, Surgical; Breast; Cohort Studies; Female; Follow-Up Stu

2018
Nitroglycerine limits infarct size through S-nitrosation of cyclophilin D: a novel mechanism for an old drug.
    Cardiovascular research, 2019, 03-01, Volume: 115, Issue:3

    Topics: Adult; Aged; Animals; Cyclophilins; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Male;

2019
Treatment of Hyaluronic Acid Filler-Induced Impending Necrosis With Hyaluronidase: Consensus Recommendations.
    Aesthetic surgery journal, 2015, Volume: 35, Issue:7

    Topics: Aspirin; Dermal Fillers; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Massage; Necrosis; Nitro

2015
Management of impending necrosis associated with soft tissue filler injections.
    Journal of drugs in dermatology : JDD, 2011, Volume: 10, Issue:9

    Topics: Adult; Antacids; Aspirin; Cosmetic Techniques; Durapatite; Female; Humans; Hyaluronic Acid; Hyaluron

2011
Nitroglycerin for severe ischaemic injury after peripheral arterial line in a preterm infant.
    Acta paediatrica (Oslo, Norway : 1992), 2013, Volume: 102, Issue:4

    Topics: Cesarean Section; Extremities; Humans; Infant, Newborn; Infant, Premature; Intensive Care Units, Neo

2013
Cardiac necrosis markers associated with low nitric oxide levels in the plasma of rabbits after treatment with vasopressin: protective effects of nitroglycerin administration.
    Pharmacological research, 2002, Volume: 45, Issue:6

    Topics: Animals; Biomarkers; Creatine Kinase; Creatine Kinase, MB Form; Electrocardiography; Fibrinogen; Iso

2002
Efficacy of topical nitroglycerin and transcutaneous electrical nerve stimulation on survival of random-pattern skin flaps in rats.
    Scandinavian journal of plastic and reconstructive surgery and hand surgery, 2003, Volume: 37, Issue:1

    Topics: Administration, Topical; Animals; Male; Necrosis; Nitroglycerin; Rats; Rats, Wistar; Surgical Flaps;

2003
Drugs modifying nitric oxide metabolism affect plasma cholesterol levels, coagulation parameters, blood pressure values and the appearance of plasma myocardial necrosis markers in rabbits: opposite effects of L-NAME and nitroglycerine.
    Cardiovascular drugs and therapy, 2003, Volume: 17, Issue:1

    Topics: Animals; Biomarkers; Blood Pressure; Cholesterol; Cholesterol, HDL; Male; Myocardium; Necrosis; NG-N

2003
Nitroglycerin, a nitric oxide generator attenuates ferric nitrilotriacetate-induced renal oxidative stress, hyperproliferative response and necrosis in ddY mice.
    Biochimica et biophysica acta, 2003, Oct-13, Volume: 1623, Issue:2-3

    Topics: Animals; Antioxidants; Cell Division; DNA; Ferric Compounds; Glutathione; Kidney; Lipid Peroxidation

2003
Morphometric and histological changes in the vascular wall after external radiation for the prevention of intimal hyperplasia.
    The Journal of surgical research, 2004, Volume: 117, Issue:2

    Topics: Acetylcholine; Animals; Aorta; Female; Fibrosis; Gamma Rays; Hyperplasia; Necrosis; Nitroglycerin; R

2004
Delayed presentation of impending necrosis following soft tissue augmentation with hyaluronic acid and successful management with hyaluronidase.
    Journal of drugs in dermatology : JDD, 2007, Volume: 6, Issue:3

    Topics: Administration, Topical; Adult; Cosmetic Techniques; Female; Humans; Hyaluronic Acid; Hyaluronogluco

2007
[Importance of a comprehensive evaluation of the size of cardiac muscle necrosis for the prognosis and treatment of acute myocardial infarct patients].
    Kardiologiia, 1984, Volume: 24, Issue:9

    Topics: Aged; Creatine Kinase; Diphosphates; Drug Therapy, Combination; Electrocardiography; Female; Heart;

1984
Relation between functional response to nitroglycerin and extent of myocardial necrosis in dogs: mapping of the left ventricle by 2-dimensional echocardiography.
    The American journal of cardiology, 1983, Volume: 52, Issue:1

    Topics: Animals; Coronary Disease; Dogs; Echocardiography; Heart; Hemodynamics; Myocardium; Necrosis; Nitrog

1983
Changes in systemic redistribution of blood flow by vasodilators.
    Japanese circulation journal, 1984, Volume: 48, Issue:4

    Topics: Animals; Blood Circulation; Blood Gas Analysis; Blood Pressure; Cardiac Output; Chlorpromazine; Dogs

1984
Enhancement of skin-flap survival using nitroglycerin ointment.
    Plastic and reconstructive surgery, 1984, Volume: 73, Issue:6

    Topics: Administration, Topical; Animals; Drug Evaluation; Graft Survival; Models, Biological; Necrosis; Nit

1984
Long-term protection of ischaemic myocardium by nitroglycerin ointment.
    Cardiovascular research, 1984, Volume: 18, Issue:5

    Topics: Animals; Collagen; Creatine Kinase; Hydroxyproline; Male; Myocardial Infarction; Myocardium; Necrosi

1984
[Coronary spasm as a mechanism of ischemia or myocardial necrosis immediately after coronary surgery. Considerations on 5 cases and review of the literature].
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:3

    Topics: Adult; Coronary Artery Bypass; Coronary Disease; Coronary Vasospasm; Humans; Intraoperative Period;

1984
[Morphological criteria of the effectiveness of nitroglycerin, dipyridamole and propranolol hydrochloride in an experimental metabolic lesion of the myocardium].
    Vrachebnoe delo, 1984, Issue:7

    Topics: Animals; Cardiomyopathies; Dipyridamole; Drug Evaluation, Preclinical; Histocytochemistry; Male; Myo

1984
[Effect of nitroglycerin on the extent of experimental myocardial necrosis].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 92, Issue:8

    Topics: Animals; Chinchilla; Heart Rate; Male; Myocardial Infarction; Myocardium; Necrosis; Nitroglycerin; R

1981
[The treatment of acute myocardial infarctions with beta-receptor-blockers. II. Hemodynamic effects of propranolol with and without combination therapy with nitroglycerin (author's transl)].
    Zeitschrift fur Kardiologie, 1981, Volume: 70, Issue:10

    Topics: Adult; Aged; Drug Therapy, Combination; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged;

1981
Role of vasodilators in the changing phases of acute myocardial infarction.
    American heart journal, 1982, Volume: 103, Issue:4 Pt 2

    Topics: Angina Pectoris; Cardiac Output; Heart Aneurysm; Humans; Ischemia; Myocardial Infarction; Necrosis;

1982
[Effect of nitroglycerin on the dimensions of the focal lesion in experimental myocardial necrosis].
    Kardiologiia, 1982, Volume: 22, Issue:10

    Topics: Animals; Drug Evaluation, Preclinical; Electrocardiography; Heart; Male; Myocardial Infarction; Necr

1982
Vasoactive mediators and the progression from oedematous to necrotising experimental acute pancreatitis.
    Gut, 1995, Volume: 37, Issue:3

    Topics: Acute Disease; Animals; Arginine; Bradykinin; Catecholamines; Ceruletide; Edema; Labetalol; Male; Mi

1995
Preventing necrosis of the skin flaps with nitroglycerin after radical resection for breast cancer.
    Journal of surgical oncology, 1993, Volume: 53, Issue:3

    Topics: Breast Neoplasms; Female; Humans; Mastectomy, Radical; Necrosis; Nitroglycerin; Surgical Flaps

1993
Effect of parenteral pentoxifylline and topical nitroglycerin on skin flap survival.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1999, Volume: 120, Issue:2

    Topics: Administration, Topical; Animals; Graft Survival; Injections, Intraperitoneal; Necrosis; Nitroglycer

1999
Glycerol trinitrate plus epidural sympathetic block in the ischemia of glans penis.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:4

    Topics: Anesthesia, Epidural; Anesthetics, Local; Anticoagulants; Autonomic Nerve Block; Bupivacaine; Child;

1999
A controlled trial of topical nitroglycerin in a New Zealand white rabbit model of brown recluse spider envenomation.
    Annals of emergency medicine, 2001, Volume: 37, Issue:2

    Topics: Administration, Cutaneous; Analysis of Variance; Animals; Blood Urea Nitrogen; Creatine Kinase; Crea

2001
[Effect of drugs on the extent of necrosis in acute myocardial infarct].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1979, Jun-11, Volume: 34, Issue:24

    Topics: Acute Disease; Adult; Aged; Heart; Humans; Male; Middle Aged; Myocardial Infarction; Myocardium; Nec

1979
[Hemodynamic and cartographic study of intravenous trinitrin in the acute stage of myocardial infarct].
    Archives des maladies du coeur et des vaisseaux, 1979, Volume: 72, Issue:4

    Topics: Acute Disease; Adult; Aged; Female; Heart; Heart Failure; Hemodynamics; Humans; Infusions, Parentera

1979
Surgical treatment of the Wolff-Parkinson-White syndrome by epicardial electrical ablation.
    The Annals of thoracic surgery, 1991, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Aged; Child; Coronary Angiography; Creatine Kinase; Electrocardiography; Electroc

1991
PAF-induced bowel necrosis. Effects of vasodilators.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:5

    Topics: Alprostadil; Animals; Hydralazine; Hypotension; Indazoles; Intestinal Diseases; Leukopenia; Male; Me

1991
[Effects of verapamil and nitroglycerin on experimental occlusion- reperfusion-induced myocardial infarction in rabbits].
    Kardiologiia, 1991, Volume: 31, Issue:1

    Topics: Animals; Coronary Vessels; Disease Models, Animal; Drug Evaluation, Preclinical; Ligation; Male; Myo

1991
Effect of nitroglycerin and a nitroglycerin-like substance in isoprenaline (ISO) necrosis and hypoxia.
    Acta physiologica Hungarica, 1990, Volume: 75 Suppl

    Topics: Animals; Hypoxia; Isoproterenol; Molsidomine; Necrosis; Nitroglycerin; Rats

1990
Use of topically applied nitroglycerin in the treatment of purpura fulminans.
    The Journal of pediatrics, 1990, Volume: 117, Issue:6

    Topics: Administration, Topical; Blood Flow Velocity; Disseminated Intravascular Coagulation; Female; Humans

1990
Glyceryl trinitrate in skin necrosis caused by extravasation of parenteral nutrition.
    Lancet (London, England), 1988, Sep-03, Volume: 2, Issue:8610

    Topics: Extravasation of Diagnostic and Therapeutic Materials; Foot Dermatoses; Humans; Infant, Newborn; Nec

1988
Comparison of different pharmacological interventions on enzymatic parameters during acute myocardial infarction.
    Clinical biochemistry, 1987, Volume: 20, Issue:6

    Topics: Adult; Aged; Clinical Enzyme Tests; Creatine Kinase; Dipyridamole; Female; Heart; Heparin; Humans; I

1987