Page last updated: 2024-11-01

nitroglycerin and Nausea

nitroglycerin has been researched along with Nausea in 14 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.

Research Excerpts

ExcerptRelevanceReference
"Patients with a Crohn's disease activity index of > or = 150 and < 450 were randomized to receive 12 weeks of either glyceryl trinitrate (initially 6 mg twice daily, increasing to 9 mg twice daily after 6 weeks) or an identical placebo."2.70Enteric-release glyceryl trinitrate in active Crohn's disease: a randomized, double-blind, placebo-controlled trial. ( Ch'Ng, CL; Evans, BK; Green, JT; Hawkes, ND; Hawthorne, AB; Kingham, JG; Mayberry, JF; Rhodes, J; Rhodes, P; Richardson, C; Swift, GL; Thomas, GA; Williams, J, 2001)
" The ratios of the Cmax were within said limits for the signal metabolite 1,2-GDN and only slightly below (0."2.69Bioavailability and pharmacokinetic profile of glyceryl trinitrate and of glyceryl dinitrates during application of a new glyceryl trinitrate transdermal patch. ( Caplain, H; Gualano, V; Rovati, LC; Santoro, A; Setnikar, I, 2000)
"The pharmacokinetic characteristics and the bioavailability of glyceryl trinitrate (GTN, CAS 55-63-0) and of its main metabolities 1,2-glyceryl dinitrate (1,2-GDN, CAS 621-65-8) and 1,3-glyceryl dinitrate (1,3-GDN, CAS 623-87-0) during a single 24-h application of three strengths of a newly developed GTN transdermal patch (Epinitril) were investigated."2.69Plasma levels of glyceryl trinitrate and dinitrates during application of three strengths of a new glyceryl trinitrate transdermal patch. ( Caplain, H; Follet, M; Gualano, V; Rovati, LC; Santoro, A; Setnikar, I, 2000)
"Non-painful symptoms in migraine following headache resolution can last up to days."1.62The migraine postdrome: Spontaneous and triggered phenotypes. ( Bose, PR; Goadsby, PJ; Karsan, N; Nagaraj, K; Peréz-Rodríguez, A, 2021)
" Use of parenteral aminophylline to treat adverse events associated with intravenous dipyridamole brought complete relief of symptoms in 439 of 454 patients (96."1.28The safety of intravenous dipyridamole thallium myocardial perfusion imaging. Intravenous Dipyridamole Thallium Imaging Study Group. ( Kempthorne-Rawson, J; Ranhosky, A, 1990)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's2 (14.29)18.2507
2000's4 (28.57)29.6817
2010's2 (14.29)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Karsan, N1
Peréz-Rodríguez, A1
Nagaraj, K1
Bose, PR1
Goadsby, PJ1
Tafoya, C1
Singh, A1
Chen, L1
Li, X1
Todd, O1
Wang, C1
Jin, H1
Du, J1
Carey, MG1
Pelter, MM1
Hausken, T1
Gilja, OH1
Odegaard, S1
Berstad, A1
Santoro, A2
Rovati, LC2
Setnikar, I2
Caplain, H2
Gualano, V2
Follet, M1
Hawkes, ND1
Richardson, C1
Ch'Ng, CL1
Green, JT1
Evans, BK1
Williams, J1
Rhodes, P1
Rhodes, J1
Swift, GL1
Thomas, GA1
Hawthorne, AB1
Kingham, JG1
Mayberry, JF1
Ranhosky, A1
Kempthorne-Rawson, J1
Gudina, ON1
Hickie, JB1
Ekbom, K1
Votcal, BE1
Lozinskij, LG1
Bogaert, MG1
Rosseel, MT1
Belpaire, FM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Habituation of the Nociceptive Blink Reflex in Experimentally Induced Migraine Attack: a Cross-over, Randomized Controlled Study[NCT05718310]22 participants (Anticipated)Interventional2022-11-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nitroglycerin and Nausea

ArticleYear
Cardiac Memory: A Case Report and Review of the Literature.
    The Journal of emergency medicine, 2019, Volume: 57, Issue:1

    Topics: Aged; Amlodipine; Arrhythmias, Cardiac; Aspirin; Bundle-Branch Block; Chest Pain; Electrocardiograph

2019

Trials

7 trials available for nitroglycerin and Nausea

ArticleYear
Flow across the human pylorus soon after ingestion of food, studied with duplex sonography. Effect of glyceryl trinitrate.
    Scandinavian journal of gastroenterology, 1998, Volume: 33, Issue:5

    Topics: Adult; Eating; Food; Gastric Emptying; Gastrointestinal Motility; Headache; Humans; Male; Nausea; Ni

1998
Bioavailability and pharmacokinetic profile of glyceryl trinitrate and of glyceryl dinitrates during application of a new glyceryl trinitrate transdermal patch.
    Arzneimittel-Forschung, 2000, Volume: 50, Issue:9

    Topics: Adhesiveness; Administration, Cutaneous; Adult; Area Under Curve; Biological Availability; Cross-Ove

2000
Plasma levels of glyceryl trinitrate and dinitrates during application of three strengths of a new glyceryl trinitrate transdermal patch.
    Arzneimittel-Forschung, 2000, Volume: 50, Issue:9

    Topics: Adhesiveness; Administration, Cutaneous; Adult; Area Under Curve; Biological Availability; Cross-Ove

2000
Enteric-release glyceryl trinitrate in active Crohn's disease: a randomized, double-blind, placebo-controlled trial.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:12

    Topics: Administration, Oral; Adult; Crohn Disease; Dizziness; Double-Blind Method; Exanthema; Female; Flush

2001
Alprenolol ("aptin") in angina pectoris. A double-blind multicentre trial.
    The Medical journal of Australia, 1970, Aug-08, Volume: 2, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Amino Alcohols; Angina Pectoris; Clinical Trials as Topic;

1970
[Carbochromen in therapy of acute and chronic coronary insufficiency].
    Arzneimittel-Forschung, 1970, Volume: 20

    Topics: Acute Disease; Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Chronic Disease;

1970
Metabolism of nitroglycerin in man: influence of phenobarbital.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 192, Issue:1

    Topics: Clinical Trials as Topic; Enzyme Induction; Headache; Humans; Male; Nausea; Nitrates; Nitroglycerin;

1971

Other Studies

6 other studies available for nitroglycerin and Nausea

ArticleYear
The migraine postdrome: Spontaneous and triggered phenotypes.
    Cephalalgia : an international journal of headache, 2021, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Fatigue; Female; Headache; Humans; Male; Middle Aged; Migraine Disorders; Nausea;

2021
A clinical manifestation-based prediction of haemodynamic patterns of orthostatic intolerance in children: a multi-centre study.
    Cardiology in the young, 2014, Volume: 24, Issue:4

    Topics: Adolescent; Blood Pressure; Chest Pain; Child; Child, Preschool; Discriminant Analysis; Dizziness; F

2014
Rapid ventricular response.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2008, Volume: 17, Issue:1

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Bundle-Branch Block; Coronary Artery Bypass; Elec

2008
The safety of intravenous dipyridamole thallium myocardial perfusion imaging. Intravenous Dipyridamole Thallium Imaging Study Group.
    Circulation, 1990, Volume: 81, Issue:4

    Topics: Adult; Aged; Aminophylline; Bronchial Spasm; Chest Pain; Dipyridamole; Female; Headache; Heart; Hemo

1990
[Neuropathologic syndromes in patients with arterial hypotension].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1974, Volume: 74, Issue:12

    Topics: Adult; Ataxia; Blood Pressure; Electrocardiography; Electroencephalography; Eye Manifestations; Fema

1974
A clinical comparison of cluster headache and migraine.
    Acta neurologica Scandinavica, 1970

    Topics: Adolescent; Adult; Aged; Carotid Arteries; Chronic Disease; Diagnosis, Differential; Ergotamine; Fem

1970