nitroglycerin has been researched along with Muscle Contraction in 286 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Topical application of nitroglycerine represents a new, easily handled, and effective alternative in the treatment of anal fissures." | 9.08 | Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy? ( Bacher, H; Cerwenka, H; El-Shabrawi, A; Mischinger, HJ; Pfeifer, J; Schweiger, W; Werkgartner, G, 1997) |
| "In the rabbit subarachnoid hemorrhage (SAH) model, the sensitivity of spastic basilar arteries to nitric oxide (NO) was enhanced whereas the endothelial function to release/produce NO became impaired, as described previously." | 5.31 | Effective improvement of the cerebral vasospasm after subarachnoid hemorrhage with low-dose nitroglycerin. ( Azuma, H; Hirakawa, K; Isotani, E; Ito, Y; Mizuno, Y, 2000) |
| "Continuous nitroglycerin (NTG) administration causes pharmacologic tolerance in humans and animals, whereas intermittent dosing is capable of avoiding or reducing tolerance development." | 5.29 | Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels. ( Bauer, JA; Fung, HL; Gopalakrishnan, M; Kwon, YW; Triggle, DJ; Zheng, W, 1993) |
| "Topical application of nitroglycerine represents a new, easily handled, and effective alternative in the treatment of anal fissures." | 5.08 | Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy? ( Bacher, H; Cerwenka, H; El-Shabrawi, A; Mischinger, HJ; Pfeifer, J; Schweiger, W; Werkgartner, G, 1997) |
| "The effectiveness of organic nitrates in the therapy of angina pectoris can be explained from their direct relaxing action on vascular smooth muscle." | 4.76 | [Effect of nitrates, nitrate-like substances, calcium antagonists and beta-adrenergic receptor blockers on peripheral circulation]. ( Bassenge, E; Busse, R, 1982) |
| " The EWBP decreased after injection of edrophonium (which increases muscle contractions) and increased following sublingual nitroglycerin administration (which relaxes muscle) in normal subjects, as well as in NE patients." | 3.83 | Low esophageal mucosal blood flow in patients with nutcracker esophagus. ( Jiang, Y; Mittal, RK, 2016) |
| "We studied the effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam (a dopamine D1-agonist) on isolated human umbilical arteries (HUA) from patients classified as normotensive and with pregnancy-induced hypertension (PIH)." | 3.72 | The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery. ( Arias, ME; Levy, JH; Sato, N; Szlam, F; Tanaka, KA; Tsuda, A, 2003) |
| " These activators inhibited tracheal smooth muscle contractions produced by acetylcholine, histamine and electrical field stimulation." | 3.69 | Activation of guanylate cyclase in the guinea-pig trachea reduces contractile responses of the smooth muscle. ( Bailey, Y; Dunkley, H; Hamilton, T; Simon, OR; Thomas, E, 1995) |
| "Five patients (one male and four female; age, 18-48 years) with symptomatic esophageal spasm were give glyceryl trinitrate (GTN) intravenously in gradually increasing doses or L-arginine on two separate occasions and underwent manometric measurements of esophageal motility after wet swallows, using a multilumen perfused catheter system (Synetics Medical, Stockholm, Sweden)." | 3.69 | Diffuse esophageal spasm: a malfunction that involves nitric oxide? ( Domschke, W; Gillessen, A; Konturek, JW, 1995) |
| " As has similarly been reported for cholinergic agents in achalasia and in some cases of diffuse oesophageal spasm the oesophageal body responded in a hypersensitive fashion to subcutaneous and intravenous injections of pentagastrin." | 3.65 | Supersensitivity to pentagastrin in diffuse oesophageal spasm. ( Eckardt, V; Weigand, H, 1974) |
| "Posture-related vasovagal syncope is by far the most frequent cause of transient loss of consciousness, and present pharmacological and cardiac pacing treatment remains unsatisfactory." | 2.70 | Management of vasovagal syncope: controlling or aborting faints by leg crossing and muscle tensing. ( Krediet, CT; Linzer, M; van Dijk, N; van Lieshout, JJ; Wieling, W, 2002) |
| "Anesthetic management and dosage schedules of vasodilators have not been standardized in many studies of aortic cross clamping (CCL)." | 2.65 | Hemodynamics of intravenous nitroglycerin during aortic clamping. ( Guffin, AV; McNeill, DC; Perdue, G; Smith, R; Zaidan, JR, 1982) |
| " This dose of ZD2574 markedly blunted the pressor response to ET-1, indicating effective blockade of ET(A) receptors, and also abolished the initial transient depressor response to ET-1, indicating that blockade of endothelial ET(B) receptors also occurred using this dosage regimen for ZD2574." | 1.31 | Endothelin receptor antagonism does not prevent the development of in vivo glyceryl trinitrate tolerance in the rat. ( Adams, MA; Bennett, BM; Fraser, AB; Ratz, JD; Rees-Milton, KJ, 2000) |
| "In the rabbit subarachnoid hemorrhage (SAH) model, the sensitivity of spastic basilar arteries to nitric oxide (NO) was enhanced whereas the endothelial function to release/produce NO became impaired, as described previously." | 1.31 | Effective improvement of the cerebral vasospasm after subarachnoid hemorrhage with low-dose nitroglycerin. ( Azuma, H; Hirakawa, K; Isotani, E; Ito, Y; Mizuno, Y, 2000) |
| " Nitroglycerin pre-exposure (10 microM for 30 min) provoked a significant shift to the right of the dose-response curve to nitroglycerin in aortae isolated from rats of 8 weeks, 12 and 18 months." | 1.29 | Nitrate tolerance and aging in isolated rat aorta. ( Berkenboom, G; Brékine, D; Fontaine, J; Unger, P, 1993) |
| " A similar pattern of vascular damage was found in rats treated with a very toxic cyclosporin treatment (50 mg." | 1.29 | Regional differences in vasculotoxic effects of cyclosporin in rats. ( de Ridder, L; Lameire, N; Van de Voorde, J; Verbeke, M, 1995) |
| " Dose-response relaxation curves were determined for acetylcholine (ACh; 10(-8) to 10(-5) M), which stimulates endothelial nitric oxide production, and for nitroglycerine (10(-9) to 10(-6) M), which directly provides nitric oxide in vivo." | 1.29 | A novel nonanticoagulant heparin prevents vascular endothelial cell dysfunction during hyperdynamic sepsis. ( Chaudry, IH; Morrison, AM; Wang, P, 1996) |
| "Continuous nitroglycerin (NTG) administration causes pharmacologic tolerance in humans and animals, whereas intermittent dosing is capable of avoiding or reducing tolerance development." | 1.29 | Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels. ( Bauer, JA; Fung, HL; Gopalakrishnan, M; Kwon, YW; Triggle, DJ; Zheng, W, 1993) |
| "The combination of hydralazine and nitrates has been shown to provide long-term benefit in congestive heart failure, despite a nitrate dosage that should induce tolerance." | 1.29 | Interaction between hydralazine and nitrovasodilators in vascular smooth muscle. ( Berkenboom, G; Fontaine, J; Unger, P, 1993) |
| " None of the K+ channel blockers had an effect on the dose-response curve to NO, on the noradrenaline-induced contraction or on the relaxation to nitroglycerine (GTN)." | 1.29 | Prejunctional modulation of the nitrergic innervation of the canine ileocolonic junction via potassium channels. ( Boeckxstaens, GE; De Man, JG; De Winter, BY; Herman, AG; Pelckmans, PP; Van Maercke, YM, 1993) |
| "While hypertension is a major risk factor for stroke, it is not its sole determinant." | 1.29 | Association and cosegregation of stroke with impaired endothelium-dependent vasorelaxation in stroke prone, spontaneously hypertensive rats. ( Condorelli, G; Ganten, D; Ganten, U; Iaccarino, G; Lindpaintner, K; Rizzoni, D; Rubattu, S; Russo, R; Trimarco, B; Vecchione, C; Volpe, M, 1996) |
| "Nitroglycerin (10(-7) M) was similarly effective in stimulating the peristalsis." | 1.28 | Stimulative effect of sodium nitroprusside on peristaltic reflex in isolated guinea pig ileal segments. ( Komori, S; Ohashi, H; Sugisawa, K; Takewaki, T, 1991) |
| "Pretreatment with iloprost did not significantly affect the concentration-response curve to any agent." | 1.28 | Relaxant effects on iloprost in canine cerebral artery. ( Cook, D; Doi, M; Kasuya, H; Weir, B; Zhang, H, 1992) |
| "Pretreatment with melatonin (10(-3) M) or M&B 22." | 1.28 | The mode of vasorelaxing action of melatonin in rabbit aorta. ( Oe, H; Satake, N; Sawada, T; Shibata, S, 1991) |
| " In rabbit isolated superior mesenteric artery, NIC exhibited two relaxation dose-response curves (DRCs): one with a lower IC50 of 4." | 1.28 | Nicorandil-induced vasorelaxation: functional evidence for K+ channel-dependent and cyclic GMP-dependent components in a single vascular preparation. ( Cipkus-Dubray, LA; Hosner, JM; Khan, SA; Meisheri, KD, 1991) |
| "Nitroglycerine was more potent in portal veins than in aortas but relaxation was fast and transient in both tissues." | 1.28 | Different time course of atrial natriuretic factor-induced relaxation in rabbit aorta and portal vein. ( Castañeda-Hernández, G; De León, H; Hong, E, 1990) |
| "5." | 1.28 | GABAA receptor-mediated stimulation of non-adrenergic non-cholinergic neurones in the dog ileocolonic junction. ( Boeckxstaens, GE; Herman, AG; Pelckmans, PA; Rampart, M; Ruytjens, IF; Van Maercke, YM; Verbeuren, TJ, 1990) |
| "Hypercholesterolemia was shown to inhibit the reactivity of the vessel's wall to the weakening action of acetylcholine due to endothelial stimulation." | 1.28 | [Effects of hypercholesterolemia on the electrical and contractile properties of the blood vessel wall]. ( Bratus', VV; Talaeva, TV; Taranenko, VM; Tishkin, SM, 1989) |
| " Dose-response curves were plotted from data obtained following exposure to histamine (10(-7)-10(-3)) and GTN (10(-9)-10(-7)) and compared to responses from age-matched untreated controls, diabetic and diabetic rats treated with insulin (2 U/day)." | 1.28 | Histamine relaxation of aortic rings from diabetic rats. ( Chang, KS; Tanz, RD; Weller, TS, 1989) |
| "Nitroglycerin was a more potent antagonist (10-10,000 fold) of contractions produced by norepinephrine in the large coronary artery than in the other three vascular beds." | 1.27 | Comparative relaxant effects of nitroglycerin in isolated rings from various canine vascular beds. ( Gharaibeh, MN; Gross, GJ, 1984) |
| " Reasonably good temporal and dose-response correlations between cyclic GMP elevation and relaxation were obtained with acetylcholine." | 1.27 | Possible role for cyclic GMP in endothelium-dependent relaxation of rabbit aorta by acetylcholine. Comparison with nitroglycerin. ( Chu, EB; Diamond, J, 1983) |
| " Two nitroglycerin dose-response curves were performed (n = 18)--one before (1st dose-response curve, from 10(-9) to 1." | 1.27 | N-acetylcysteine does not modify nitroglycerin-induced tolerance in canine vascular rings. ( Abdollah, A; Armstrong, PW; Moffat, JA, 1987) |
| "Methylene blue pretreatment produced approximately 5-fold shifts to the right of both nitroglycerin and nitroprusside relaxation curves." | 1.27 | Nitroglycerin tolerance and cyclic GMP generation in the longitudinal smooth muscle of the guinea-pig ileum. ( Burkman, AM; Fertel, RH; Keith, RA; Sokoloski, TD, 1983) |
| "Nitroglycerin was less effective than nitroprusside in elevating cyclic GMP levels, but was an effective relaxant in both tissues." | 1.27 | Lack of correlation between cyclic GMP elevation and relaxation of nonvascular smooth muscle by nitroglycerin, nitroprusside, hydroxylamine and sodium azide. ( Diamond, J, 1983) |
| "Anoxia has been shown to potentiate the constrictor effects of 5-hydroxytryptamine (5HT) in isolated vascular tissue." | 1.27 | Effects of nitroglycerin, dipyridamole, nifedipine, verapamil and diltiazem on canine coronary arterial rings contracted with 5-hydroxytryptamine and anoxia. ( Balkon, J; Barrett, JA; DePaul Lynch, V; Smith, RD; Wolf, PS, 1986) |
| " Isolated bovine pulmonary arteries and veins were contracted submaximally and cumulative dose-response relationships to glyceryl trinitrate were obtained; the vein was approximately 10 times more sensitive than the artery to glyceryl trinitrate induced relaxation." | 1.27 | A comparative study of glyceryl trinitrate biotransformation and glyceryl trinitrate induced relaxation in bovine pulmonary artery and vein. ( Brien, JF; Kawamoto, JH; Marks, GS; Nakatsu, K, 1987) |
| "Papaverine was shown to be the substance able to cause the biggest relaxation effect." | 1.27 | Relaxation of isolated corpus cavernosum induced by smooth-muscle relaxant drugs. A comparative study. ( Barbanti, G; Beneforti, P; Lapini, A; Turini, D, 1988) |
| "In both these models of ergotism, the directly acting vasodilator nitroglycerine (NTG) effectively relieved the ergotamine-induced arterial contractions." | 1.26 | Nitroglycerin for ergotism. Experimental studies in vitro and in migraine patients and treatment of an overt case. ( Gøthgen, I; Husum, B; Jacobsen, E; Ostergaard, JR; Rasmussen, JP; Tfelt-Hansen, P, 1982) |
| "Papaverine was assumed to produce a relaxation through augmentation of the calcium binding to the intercellular store sites for calcium as well as through inhibition of the calcium influx." | 1.26 | A comparison of the differential effects of nitroglycerin, nifedipine and papaverine on contractures induced in vascular and intestinal smooth muscle by potassium and lanthanum. ( Imai, S; Kitagawa, T, 1981) |
| " When arterial strips were processed by radioimmunoassay for dosage of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) after the relaxing action of the contrast medium occurred, a decrease in cAMP from 2." | 1.26 | Effects of angiographic contrast medium on isolated canine coronary arteries. ( Cingolani, H; Lardani, H; Rinaldi, G, 1982) |
| " The dose-response curve shifted to the right in the presence of NG noncompetitively in all the conditions employed to develop the tension." | 1.26 | Actions of nitroglycerine on the membrane and mechanical properties of smooth muscles of the coronary artery of the pig. ( Ito, Y; Kitamura, K; Kuriyama, H, 1980) |
| "Nitroglycerin (0." | 1.26 | The effect of sublingually administered nitroglycerin on the contraction of the human gallbladder. ( Kanto, J; Katevuo, K, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 149 (52.10) | 18.7374 |
| 1990's | 99 (34.62) | 18.2507 |
| 2000's | 28 (9.79) | 29.6817 |
| 2010's | 9 (3.15) | 24.3611 |
| 2020's | 1 (0.35) | 2.80 |
| Authors | Studies |
|---|---|
| Shan, R | 1 |
| Velazquez, C | 1 |
| Knaus, EE | 1 |
| Rotarius, TR | 1 |
| Lauver, JD | 1 |
| Thistlethwaite, JR | 1 |
| Scheuermann, BW | 1 |
| Vecherskiĭ, IuIu | 1 |
| Andreev, SL | 1 |
| Zatolokin, VV | 1 |
| Gusakova, SV | 1 |
| Kovalev, IV | 3 |
| Eremenko, KV | 1 |
| Dronova, IV | 1 |
| Jiang, Y | 1 |
| Mittal, RK | 1 |
| Toque, HA | 1 |
| Priviero, FB | 2 |
| Zemse, SM | 1 |
| Antunes, E | 2 |
| Teixeira, CE | 2 |
| Webb, RC | 2 |
| Gupte, SA | 1 |
| Kaminski, PM | 1 |
| George, S | 1 |
| Kouznestova, L | 1 |
| Olson, SC | 1 |
| Mathew, R | 1 |
| Hintze, TH | 1 |
| Wolin, MS | 3 |
| Van Hove, CE | 2 |
| Van der Donckt, C | 1 |
| Herman, AG | 9 |
| Bult, H | 2 |
| Fransen, P | 1 |
| Palecek, T | 1 |
| Lubanda, JC | 1 |
| Trckova, R | 1 |
| Linhart, A | 1 |
| Pant, J | 1 |
| Ranjan, P | 1 |
| Deshpande, SB | 1 |
| Fadel, PJ | 1 |
| Farias Iii, M | 1 |
| Gallagher, KM | 1 |
| Wang, Z | 1 |
| Thomas, GD | 1 |
| Birk, GK | 2 |
| Dawson, EA | 2 |
| Atkinson, C | 1 |
| Haynes, A | 1 |
| Cable, NT | 1 |
| Thijssen, DH | 2 |
| Green, DJ | 3 |
| Colussi, C | 1 |
| Scopece, A | 1 |
| Vitale, S | 1 |
| Spallotta, F | 1 |
| Mattiussi, S | 1 |
| Rosati, J | 1 |
| Illi, B | 1 |
| Mai, A | 1 |
| Castellano, S | 1 |
| Sbardella, G | 1 |
| Farsetti, A | 1 |
| Capogrossi, MC | 1 |
| Gaetano, C | 1 |
| Timothy Cable, N | 1 |
| Spence, AL | 1 |
| Carter, HH | 1 |
| Naylor, LH | 1 |
| Krediet, CT | 1 |
| van Dijk, N | 1 |
| Linzer, M | 1 |
| van Lieshout, JJ | 1 |
| Wieling, W | 1 |
| Sato, N | 2 |
| Tanaka, KA | 1 |
| Szlam, F | 2 |
| Tsuda, A | 1 |
| Arias, ME | 1 |
| Levy, JH | 2 |
| Ortega, A | 2 |
| Avellanal, M | 1 |
| España, G | 1 |
| Flores, A | 1 |
| Aleixandre, A | 1 |
| Baskakov, MB | 2 |
| Medvedev, MA | 2 |
| Borodin, IuL | 1 |
| Popov, AA | 1 |
| Minochenko, IL | 1 |
| Anfinogenova, IaD | 1 |
| Kapilevich, LV | 2 |
| de la Lande, IS | 3 |
| Siebert, TE | 1 |
| Bennett, CL | 1 |
| Stafford, I | 2 |
| Horowitz, JD | 3 |
| Costagliola, A | 1 |
| De Man, JG | 3 |
| Majewski, M | 1 |
| Lakomy, M | 1 |
| Cecio, A | 1 |
| Robberecht, P | 1 |
| Pelckmans, PA | 4 |
| Adriaensen, D | 1 |
| Timmermans, JP | 1 |
| Bény, JL | 1 |
| Xue, L | 1 |
| Locke, GR | 1 |
| Camilleri, M | 1 |
| Schuurkes, JA | 1 |
| Meulemans, A | 1 |
| Coulie, BJ | 1 |
| Szurszewski, JH | 1 |
| Farrugia, G | 1 |
| Claudino, MA | 1 |
| Baracat, JS | 1 |
| De Nucci, G | 1 |
| McGowan, CL | 1 |
| Levy, AS | 1 |
| Millar, PJ | 1 |
| Guzman, JC | 1 |
| Morillo, CA | 1 |
| McCartney, N | 1 |
| Macdonald, MJ | 1 |
| Esplugues, JV | 1 |
| Rocha, M | 1 |
| Nuñez, C | 1 |
| Bosca, I | 1 |
| Ibiza, S | 1 |
| Herance, JR | 1 |
| Serrador, JM | 1 |
| D'Ocon, P | 1 |
| Victor, VM | 1 |
| Crisafulli, A | 1 |
| Melis, F | 1 |
| Tocco, F | 1 |
| Pittau, G | 1 |
| Lorrai, L | 1 |
| Gori, T | 1 |
| Mancardi, D | 1 |
| Concu, A | 1 |
| Pagliaro, P | 1 |
| Jones, OM | 1 |
| Munir, S | 1 |
| Jiang, B | 1 |
| Guilcher, A | 1 |
| Brett, S | 1 |
| Redwood, S | 1 |
| Marber, M | 1 |
| Chowienczyk, P | 1 |
| Kreye, VA | 1 |
| Gruetter, CA | 4 |
| Kadowitz, PJ | 3 |
| Ignarro, LJ | 4 |
| Busse, R | 2 |
| Bassenge, E | 2 |
| Sugimoto, J | 1 |
| Syoji, N | 1 |
| Mizuno, K | 1 |
| Morita, M | 1 |
| Sakanashi, M | 4 |
| Takeo, S | 1 |
| Ito, H | 1 |
| Noguchi, K | 3 |
| Miyamato, Y | 1 |
| Higa, T | 1 |
| Karashima, T | 2 |
| Itoh, T | 5 |
| Kuriyama, H | 6 |
| Nabata, H | 1 |
| Sakai, K | 2 |
| Kobayashi, A | 1 |
| Suzuki, Y | 1 |
| Kamikawa, T | 1 |
| Hayashi, H | 1 |
| Yamazaki, N | 1 |
| Braughler, JM | 1 |
| Gruetter, DY | 1 |
| Lyon, JE | 1 |
| Axelsson, KL | 9 |
| Andersson, RG | 6 |
| Wikberg, JE | 4 |
| Lardani, H | 1 |
| Rinaldi, G | 2 |
| Cingolani, H | 2 |
| Keith, RA | 1 |
| Burkman, AM | 1 |
| Sokoloski, TD | 1 |
| Fertel, RH | 1 |
| Diamond, J | 5 |
| Chu, EB | 1 |
| Burke, TM | 1 |
| Wood, KS | 1 |
| Byrick, RJ | 1 |
| Hobbs, EG | 1 |
| Martineau, R | 1 |
| Noble, WH | 1 |
| Bennett, BM | 2 |
| Moffat, JA | 2 |
| Armstrong, PW | 3 |
| Marks, GS | 5 |
| Muramatsu, I | 1 |
| Fujii, K | 1 |
| Sakakibara, Y | 1 |
| Fujiwara, M | 3 |
| Ueno, H | 1 |
| Haver, VM | 1 |
| Namm, DH | 1 |
| Karaki, H | 3 |
| Murakami, K | 2 |
| Nakagawa, H | 1 |
| Urakawa, N | 2 |
| Drummond, WH | 1 |
| Brown, BG | 1 |
| Lee, AB | 1 |
| Bolson, EL | 1 |
| Dodge, HT | 1 |
| Tsukada, T | 1 |
| Imai, S | 5 |
| Rubio, R | 1 |
| Berne, R | 1 |
| Gharaibeh, MN | 1 |
| Gross, GJ | 1 |
| Lemke, SM | 2 |
| Glisson, SN | 1 |
| Sanchez, MM | 1 |
| El-Etr, AA | 1 |
| Lim, RA | 1 |
| Watkins, RW | 1 |
| Davidson, IW | 1 |
| Ginsburg, R | 2 |
| Bristow, MR | 1 |
| Harrison, DC | 1 |
| Stinson, EB | 1 |
| Armstrong, JA | 1 |
| Ito, Y | 3 |
| Kitamura, K | 2 |
| Oguro, K | 1 |
| Ono, H | 1 |
| Ross, G | 1 |
| Stinson, E | 1 |
| Schroeder, J | 1 |
| Kitagawa, T | 1 |
| Casteels, R | 1 |
| Raeymaekers, L | 1 |
| Suzuki, H | 2 |
| Van Eldere, J | 1 |
| Tfelt-Hansen, P | 1 |
| Ostergaard, JR | 1 |
| Gøthgen, I | 1 |
| Jacobsen, E | 1 |
| Rasmussen, JP | 1 |
| Husum, B | 1 |
| Zaidan, JR | 1 |
| Guffin, AV | 1 |
| Perdue, G | 1 |
| Smith, R | 1 |
| McNeill, DC | 1 |
| Toda, N | 5 |
| Usui, H | 6 |
| Osumi, S | 1 |
| Kanda, M | 1 |
| Kitao, K | 1 |
| Torfgård, KE | 1 |
| Svedjeholm, R | 1 |
| Håkansson, E | 1 |
| Ahlner, J | 5 |
| Bauer, JA | 1 |
| Fung, HL | 1 |
| Zheng, W | 1 |
| Kwon, YW | 1 |
| Gopalakrishnan, M | 1 |
| Triggle, DJ | 1 |
| Okamura, T | 2 |
| He, GW | 3 |
| Yang, CQ | 3 |
| Wilson, GJ | 1 |
| Rebeyka, IM | 1 |
| Kojda, G | 1 |
| Beck, JK | 1 |
| Meyer, W | 1 |
| Noack, E | 1 |
| Green, K | 1 |
| Campbell, G | 1 |
| Münzel, T | 1 |
| Giaid, A | 1 |
| Kurz, S | 1 |
| Stewart, DJ | 1 |
| Harrison, DG | 2 |
| Ishibashi, T | 2 |
| Kawada, T | 1 |
| Kato, K | 2 |
| Hamaguchi, M | 1 |
| Bank, AJ | 2 |
| Wilson, RF | 1 |
| Kubo, SH | 2 |
| Holte, JE | 2 |
| Dresing, TJ | 1 |
| Wang, H | 2 |
| Zhang, CL | 1 |
| Singer, AH | 1 |
| Tsao, PS | 1 |
| Wang, BY | 1 |
| Bloch, DA | 1 |
| Cooke, JP | 1 |
| Jino, H | 3 |
| Kurahashi, K | 6 |
| Shirahase, H | 2 |
| Nakata, Y | 2 |
| Shimizu, Y | 2 |
| Onoue, H | 2 |
| Kaito, N | 1 |
| Tokudome, S | 1 |
| Abe, T | 1 |
| Tashibu, K | 1 |
| Nagashima, H | 1 |
| Nakamura, N | 1 |
| Unger, P | 2 |
| Berkenboom, G | 2 |
| Fontaine, J | 2 |
| Zhou, Q | 1 |
| Satake, N | 3 |
| Shibata, S | 7 |
| Mack, MJ | 1 |
| Acuff, TE | 1 |
| Ryan, WH | 1 |
| Starr, A | 1 |
| Magnon, M | 1 |
| Durand, I | 1 |
| Cavero, I | 2 |
| Salas, E | 1 |
| López, MG | 1 |
| Villarroya, M | 1 |
| Sánchez-García, P | 1 |
| De Pascual, R | 1 |
| Dixon, WR | 1 |
| García, AG | 1 |
| Verbeke, M | 2 |
| Van de Voorde, J | 2 |
| de Ridder, L | 2 |
| Lameire, N | 2 |
| Isono, T | 1 |
| Yamamoto, T | 1 |
| Sawada, T | 2 |
| Yamazaki, S | 1 |
| Miura, S | 1 |
| Furuichi, A | 1 |
| Ozaki, R | 1 |
| Koibuchi, Y | 1 |
| Ohtsuka, M | 1 |
| Desai, KM | 1 |
| Warner, TD | 1 |
| Vane, JR | 1 |
| Antonaccio, MJ | 1 |
| Normandin, D | 1 |
| Ferrer, P | 1 |
| Fukazawa, M | 1 |
| Namiki, A | 1 |
| Boeckxstaens, GE | 4 |
| Van Maercke, YM | 4 |
| Brékine, D | 1 |
| Pelckmans, PP | 1 |
| De Winter, BY | 1 |
| Taub, HC | 1 |
| Lerner, SE | 1 |
| Melman, A | 1 |
| Christ, GJ | 1 |
| Abe, A | 1 |
| Venturini, CM | 1 |
| Palmer, RM | 2 |
| Moncada, S | 2 |
| Luo, DL | 1 |
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| del Monte, F | 1 |
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| Nagai, K | 1 |
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| Fukami, Y | 1 |
| Toki, Y | 1 |
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| Mukawa, H | 1 |
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| Capasso, A | 1 |
| Sorrentino, L | 1 |
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| Xiao, S | 1 |
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| Hooker, CS | 1 |
| Calkins, PJ | 1 |
| Fermum, R | 2 |
| Klinner, U | 2 |
| Meisel, P | 2 |
| Toma, TP | 1 |
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| Akimoto, Y | 3 |
| Hu, ZW | 1 |
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| Hoffman, BB | 2 |
| Shaw, J | 1 |
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| Hendle, PN | 1 |
| Baird, DK | 1 |
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| Magnusson, B | 1 |
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| Weir, B | 1 |
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| Cook, D | 1 |
| Jett, GK | 1 |
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| Hatcher, CR | 1 |
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| Weston, AH | 1 |
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| Weidinger, F | 1 |
| Krejcy, K | 1 |
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| Nakasone, J | 2 |
| Matsuzaki, T | 1 |
| Aniya, Y | 2 |
| Uezu, K | 1 |
| Taranenko, VM | 3 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Resistance Training and Cardiometabolic Health[NCT03325933] | 62 participants (Actual) | Interventional | 2017-09-21 | Terminated (stopped due to COVID-19) | |||
| A Pivotal Study To Evaluate The Effectiveness of Isometric Handgrip Therapy In Prehypertensive And Hypertensive Patients[NCT04467879] | 146 participants (Actual) | Interventional | 2020-06-01 | Terminated (stopped due to New Protocol and Outcome Measures in Review) | |||
| Inflammatory Pathogenesis of Coronary Atherosclerosis in HIV[NCT02624180] | Phase 2 | 81 participants (Actual) | Interventional | 2015-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Brachial Flow Mediated Dilatation (FMD) at 24 Weeks. (NCT02624180)
Timeframe: At 24 weeks
| Intervention | % brachial artery dilation (Median) |
|---|---|
| Colchicine | 3.82 |
| Placebo | 3.46 |
Brachial flow mediated dilatation (FMD) at 8 weeks. (NCT02624180)
Timeframe: At 8 weeks
| Intervention | % brachial artery dilation (Median) |
|---|---|
| Colchicine | 4.26 |
| Placebo | 4.12 |
Change in CSA as measured by the difference between CSA at rest and under IHE stress at 24 weeks (NCT02624180)
Timeframe: At 24 weeks
| Intervention | Percent change from rest measurement (Median) |
|---|---|
| Colchicine | -0.96 |
| Placebo | 5.04 |
Change in CSA as measured by the difference between CSA at rest and under IHE stress at 8 weeks (NCT02624180)
Timeframe: Difference between measurements at baseline compared to measurement at 8 weeks
| Intervention | Percent change from baseline measurement (Median) |
|---|---|
| Colchicine | -0.10 |
| Placebo | 1.53 |
Change in coronary blood flow (CBF) from rest to that during isometric handgrip exercise (IHE) stress at 24 weeks. (NCT02624180)
Timeframe: At 24 weeks.
| Intervention | Percent change from rest measurement (Median) |
|---|---|
| Colchicine | -1.27 |
| Placebo | 16.60 |
Percent change in coronary blood flow (CBF) from rest to that during isometric handgrip exercise (IHE) stress at 8 weeks. (NCT02624180)
Timeframe: Difference between measurements at baseline compared to measurement at 8 weeks
| Intervention | Percent change from rest measurement (Mean) |
|---|---|
| Colchicine | 8.1 |
| Placebo | 13.4 |
High-sensitivity C-reactive Protein (hsCRP) at 24 weeks (NCT02624180)
Timeframe: At 24 weeks
| Intervention | mg/l (Median) |
|---|---|
| Colchicine | 1.00 |
| Placebo | 1.30 |
High-sensitivity C-reactive protein (hsCRP) at 8 weeks (NCT02624180)
Timeframe: At 8 weeks.
| Intervention | mg/l (Median) |
|---|---|
| Colchicine | 1.65 |
| Placebo | 1.26 |
Interleukin-6 (IL-6) at 8 weeks (NCT02624180)
Timeframe: At 8 weeks
| Intervention | pg/ml (Median) |
|---|---|
| Colchicine | 0.53 |
| Placebo | 0.64 |
6 reviews available for nitroglycerin and Muscle Contraction
| Article | Year |
|---|---|
Direct vasodilators with unknown modes of action: the nitro-compounds and hydralazine.
Topics: Animals; Calcium; Cell Membrane; Cyclic GMP; Humans; Hydralazine; Muscle Contraction; Muscle Protein | 1984 |
[Effect of nitrates, nitrate-like substances, calcium antagonists and beta-adrenergic receptor blockers on peripheral circulation].
Topics: Adrenergic beta-Antagonists; Amyl Nitrite; Angina Pectoris; Animals; Blood Circulation; Calcium Chan | 1982 |
Persistent pulmonary hypertension of the neonate (persistent fetal circulation syndrome).
Topics: Acetylcholine; Calcium; Catecholamines; Epoprostenol; Homeostasis; Humans; Hypertension, Pulmonary; | 1983 |
[Dynamic left ventricular obstruction increased by nitroglycerin in elderly patients with hypertension and concentric left ventricular hypertrophy].
Topics: Aged; Cardiomegaly; Cardiomyopathy, Hypertrophic; Echocardiography; Female; Heart Ventricles; Humans | 1990 |
Esophageal physiology.
Topics: Atropine; Barium Sulfate; Deglutition; Esophageal Achalasia; Esophageal Diseases; Esophagus; Gastrin | 1974 |
Organic nitrates in angina pectoris.
Topics: Administration, Oral; Amyl Nitrite; Angina Pectoris; Blood Pressure; Coronary Circulation; Drug Tole | 1972 |
11 trials available for nitroglycerin and Muscle Contraction
| Article | Year |
|---|---|
Oxidative stress and enhanced sympathetic vasoconstriction in contracting muscles of nitrate-tolerant rats and humans.
Topics: Adult; Animals; Biomarkers; F2-Isoprostanes; Humans; Male; Models, Animal; Muscle Contraction; Muscl | 2012 |
A prospective randomized longitudinal study involving 6 months of endurance or resistance exercise. Conduit artery adaptation in humans.
Topics: Adaptation, Physiological; Adult; Analysis of Variance; Arteries; Brachial Artery; Carotid Arteries; | 2013 |
Management of vasovagal syncope: controlling or aborting faints by leg crossing and muscle tensing.
Topics: Adolescent; Adult; Aged; Blood Pressure; Disease Management; Exercise Movement Techniques; Female; H | 2002 |
Acute vascular responses to isometric handgrip exercise and effects of training in persons medicated for hypertension.
Topics: Aged; Endothelium, Vascular; Exercise; Exercise Therapy; Forearm; Hand Strength; Humans; Hypertensio | 2006 |
Hemodynamics of intravenous nitroglycerin during aortic clamping.
Topics: Aorta, Abdominal; Aortic Aneurysm; Aortic Diseases; Arteriosclerosis; Blood Circulation; Cardiac Out | 1982 |
Tolerance development and arterial and venous tissue-/plasma levels of glyceryl trinitrate and glyceryl dinitrate in patients treated with nitroglycerin infusion.
Topics: Aged; Blood Vessels; Drug Tolerance; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Musc | 1995 |
Effects of glyceryl trinitrate on the pyloric motor response to intraduodenal triglyceride infusion in humans.
Topics: Adolescent; Adult; Blood Pressure; Duodenum; Heart Rate; Humans; Male; Muscle Contraction; Nitric Ox | 1996 |
Sublingual nitroglycerine: effects on contractile activity of the distal oesophagus and lower oesophageal sphincter in healthy men.
Topics: Administration, Sublingual; Adult; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Me | 1996 |
Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy?
Topics: Acute Disease; Administration, Rectal; Administration, Topical; Adult; Anal Canal; Anesthetics, Loca | 1997 |
Effect of glyceryl trinitrate on proximal stomach musculature in normal volunteers.
Topics: Adult; Gastric Fundus; Humans; Manometry; Muscle Contraction; Nitroglycerin; Random Allocation; Refe | 1992 |
[The local effect of nitroglycerin ointment in dilating veins. A possible aid in establishing drip infusions].
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infusions, Parenteral; Male; Muscle C | 1985 |
269 other studies available for nitroglycerin and Muscle Contraction
| Article | Year |
|---|---|
Syntheses, calcium channel agonist-antagonist modulation activities, and nitric oxide release studies of nitrooxyalkyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-(2,1,3-benzoxadiazol-4-yl)pyridine-5-carboxylate racemates, enantiomers, and diastereomers.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Guinea Pigs; Heart; Ileum; In Vitro Techniques; | 2004 |
Muscle blood flow is independent of conduit artery diameter following prior vasodilation in males.
Topics: Adult; Blood Flow Velocity; Brachial Artery; Exercise; Forearm; Hemodynamics; Humans; Male; Muscle C | 2021 |
[In vitro study of the radial artery vasodilatory reactions].
Topics: Chlorpromazine; Dopamine Antagonists; Heparin; Humans; Muscle Contraction; Muscle, Smooth; Nifedipin | 2014 |
Low esophageal mucosal blood flow in patients with nutcracker esophagus.
Topics: Adult; Aged; Chest Pain; Esophageal Motility Disorders; Esophagus; Female; Humans; Ischemia; Laser-D | 2016 |
Effect of the phosphodiesterase 5 inhibitors sildenafil, tadalafil and vardenafil on rat anococcygeus muscle: functional and biochemical aspects.
Topics: Animals; Carbolines; Drug Evaluation, Preclinical; Enzyme Inhibitors; Guanylate Cyclase; Imidazoles; | 2009 |
Peroxide generation by p47phox-Src activation of Nox2 has a key role in protein kinase C-induced arterial smooth muscle contraction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Cattle; Coronary | 2009 |
Vasodilator efficacy of nitric oxide depends on mechanisms of intracellular calcium mobilization in mouse aortic smooth muscle cells.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcium; Calcium Channels, L-Type; Cyclic GMP; Hydrazines; | 2009 |
Left atrial flow propagation velocity: a new approach for assessment of left atrial reservoir function.
Topics: Adult; Analysis of Variance; Atrial Function, Left; Blood Flow Velocity; Compliance; Echocardiograph | 2011 |
Bisphenol A decreases atrial contractility involving NO-dependent G-cyclase signaling pathway.
Topics: Animals; Atropine; Benzhydryl Compounds; Cardiotoxins; Enzyme Inhibitors; Guanylate Cyclase; Heart A | 2011 |
Brachial artery adaptation to lower limb exercise training: role of shear stress.
Topics: Adaptation, Physiological; Adult; Analysis of Variance; Bicycling; Brachial Artery; Endothelium, Vas | 2012 |
P300/CBP associated factor regulates nitroglycerin-dependent arterial relaxation by N(ε)-lysine acetylation of contractile proteins.
Topics: Acetylation; Actins; Animals; Aorta; Benzamides; Cyclic GMP; Histone Deacetylase Inhibitors; Hydroxa | 2012 |
Effect of unilateral forearm inactivity on endothelium-dependent vasodilator function in humans.
Topics: Analysis of Variance; Blood Flow Velocity; Brachial Artery; Endothelium, Vascular; Forearm; Hand Str | 2013 |
The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Dopamine; Dose-Response Relation | 2003 |
Effect of nitroglycerine in popliteal preparations from patients with peripheral occlusive arteriopathy precontracted with KCl or 5-hydroxytryptamine.
Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Dose-Response Relationship, Drug; Electric Sti | 2003 |
[Myogenic effects of cyclic guanosine monophosphate in smooth muscle cells. Role of protein kinase C].
Topics: Action Potentials; Animals; Colon; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; | 2003 |
Influence of the endothelium on ex vivo tolerance and metabolism of glyceryl trinitrate in rat aorta.
Topics: Animals; Aorta; Chromatography, Gas; Drug Tolerance; Endothelium, Vascular; In Vitro Techniques; Mus | 2004 |
Coexistence of non-adrenergic non-cholinergic inhibitory and excitatory neurotransmitters in a large neuronal subpopulation in the vaginal segment of the chicken oviduct.
Topics: Adrenergic Agents; Animals; Atropine; Chickens; Dose-Response Relationship, Drug; Dose-Response Rela | 2004 |
Characterization of purine receptors in mouse thoracic aorta.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adenosine; Adenos | 2004 |
Effect of modulation of serotonergic, cholinergic, and nitrergic pathways on murine fundic size and compliance measured by ultrasonomicrometry.
Topics: Animals; Atropine; Bethanechol; Buspirone; Gastric Fundus; Male; Mice; Muscle Contraction; Muscle, S | 2006 |
Stimulation of soluble guanylyl cyclase by BAY 41-2272 relaxes anococcygeus muscle: interaction with nitric oxide.
Topics: Animals; Carbachol; Carbolines; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; | 2006 |
Complex I dysfunction and tolerance to nitroglycerin: an approach based on mitochondrial-targeted antioxidants.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Antioxidants; Cyclic GMP; Do | 2006 |
Delayed preconditioning-mimetic actions of exercise or nitroglycerin do not affect haemodynamics and exercise performance in trained or sedentary individuals.
Topics: Adult; Cardiac Output; Endothelium; Exercise; Facial Muscles; Heart Rate; Hemodynamics; Humans; Isch | 2007 |
Towards safer treatments for benign anorectal disease: the pharmacological manipulation of the internal anal sphincter.
Topics: Anal Canal; Anus Diseases; Botulinum Toxins; Gastrointestinal Agents; Humans; Muscle Contraction; Ni | 2007 |
Exercise reduces arterial pressure augmentation through vasodilation of muscular arteries in humans.
Topics: Adaptation, Physiological; Bicycling; Blood Flow Velocity; Blood Pressure; Brachial Artery; Carotid | 2008 |
Methylene blue inhibits coronary arterial relaxation and guanylate cyclase activation by nitroglycerin, sodium nitrite, and amyl nitrite.
Topics: Amyl Nitrite; Animals; Cattle; Coronary Vessels; Enzyme Activation; Guanylate Cyclase; In Vitro Tech | 1981 |
Increase in Ca2+ (Mg2+)-ATPase activity induced by a molsidomine derivative (SIN-1 A) and nitroglycerin in microsomal fraction of guinea-pig thoracic aorta.
Topics: Animals; Aorta, Thoracic; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium-Transporting ATPases; Dinoprost; Fe | 1984 |
Effects of an antihypertensive agent, nipradilol, on isolated coronary artery of the dog.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Coronary Vessels; Dogs; Female; In Vi | 1984 |
Effects of 2-nicotinamidoethyl nitrate on smooth muscle cells of the guinea-pig mesenteric and portal veins.
Topics: Acetylcholine; Animals; Female; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Membran | 1982 |
Effects of a new antianginal agent, nicorandil, on normoxic and anoxic contractions in isolated miniature pig coronary arteries exposed to 5-hydroxytryptamine and norepinephrine: comparison with nitroglycerin and diltiazem.
Topics: Animals; Benzazepines; Coronary Vessels; Diltiazem; Drug Interactions; Female; Male; Muscle Contract | 1983 |
The effects of nitroglycerin on cyclic nucleotides in the coronary artery in vivo.
Topics: Animals; Coronary Circulation; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dogs; Muscle Contraction; M | 1980 |
Dissociation of increases in cyclic GMP from relaxation of arterial smooth muscle.
Topics: Animals; Cyclic GMP; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smoot | 1981 |
Relationship between cyclic guanosine 3':5'-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: effects of methylene blue and methemoglobin.
Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; In Vitro Techniques; Methemoglobin; Methylene Blue; M | 1981 |
Correlation between vascular smooth muscle relaxation and increase in cyclic GMP induced by some organic nitro esters.
Topics: Animals; Cattle; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Ethylene Glycols; In Vitr | 1981 |
Vascular smooth muscle relaxation by nitro compounds: reduced relaxation and cGMP elevation in tolerant vessels and reversal of tolerance by dithiothreitol.
Topics: Animals; Cattle; Cyclic AMP; Cyclic GMP; Dithiothreitol; Drug Tolerance; Ferricyanides; Glutathione; | 1982 |
Effects of angiographic contrast medium on isolated canine coronary arteries.
Topics: Animals; Contrast Media; Coronary Angiography; Coronary Vessels; Cyclic AMP; Dogs; Dose-Response Rel | 1982 |
Nitroglycerin tolerance and cyclic GMP generation in the longitudinal smooth muscle of the guinea-pig ileum.
Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Female; Guinea Pigs; Ileum; M | 1983 |
Lack of correlation between cyclic GMP elevation and relaxation of nonvascular smooth muscle by nitroglycerin, nitroprusside, hydroxylamine and sodium azide.
Topics: Animals; Azides; Colon; Cyclic GMP; Female; Guinea Pigs; Hydroxylamine; Hydroxylamines; Male; Muscle | 1983 |
Possible role for cyclic GMP in endothelium-dependent relaxation of rabbit aorta by acetylcholine. Comparison with nitroglycerin.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Cyclic GMP; Endothelium; Female; In Vitro Techniques; Male; | 1983 |
The effect of substituted sydnonimines on coronary smooth muscle relaxation and cyclic guanosine monophosphate levels.
Topics: Animals; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Female; I | 1983 |
Association between cyclic GMP accumulation and acetylcholine-elicited relaxation of bovine intrapulmonary artery.
Topics: Acetylcholine; Animals; Cattle; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endotheliu | 1984 |
Nitroglycerin relaxes large airways.
Topics: Adult; Aged; Anesthesia, Intravenous; Blood Pressure; Dose-Response Relationship, Drug; Humans; Midd | 1983 |
Investigation of the role of prostaglandins in nitroglycerin-induced relaxation of isolated rabbit blood vessels.
Topics: Animals; Arachidonic Acids; Bradykinin; Celiac Artery; In Vitro Techniques; Indomethacin; Male; Mese | 1983 |
Vasorelaxing actions of molsidomine and its metabolites, in comparison with nitroglycerin.
Topics: Animals; Calcium; Dogs; Female; Male; Methemoglobin; Methylene Blue; Molsidomine; Muscle Contraction | 1983 |
Mechanisms of the nitroglycerine-induced vasodilation in vascular smooth muscles of the rabbit and pig.
Topics: Animals; Caffeine; Calcium; Female; Male; Muscle Contraction; Muscle Proteins; Muscle, Smooth, Vascu | 1983 |
Characterization of the thrombin-induced contraction of vascular smooth muscle.
Topics: Animals; Aorta, Thoracic; Coronary Vessels; Dogs; Heparin; Hirudins; Muscle Contraction; Muscle, Smo | 1984 |
Nitroglycerine-induced biphasic relaxation in vascular smooth muscle of rat aorta.
Topics: Animals; Aorta, Thoracic; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, | 1984 |
Reflex constriction of significant coronary stenosis as a mechanism contributing to ischemic left ventricular dysfunction during isometric exercise.
Topics: Adult; Aged; Constriction, Pathologic; Coronary Angiography; Coronary Disease; Coronary Vessels; Hea | 1984 |
[Sympathetic nervous system and response of the coronary artery to some drugs].
Topics: Adenosine; Animals; Coronary Vessels; Dogs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, | 1983 |
Comparative relaxant effects of nitroglycerin in isolated rings from various canine vascular beds.
Topics: Animals; Dogs; Female; Femoral Artery; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contra | 1984 |
Parenchymal and vascular strips from bovine lung respond differently to vasodilators.
Topics: Animals; Cattle; Dose-Response Relationship, Drug; In Vitro Techniques; Lung; Muscle Contraction; Mu | 1984 |
Nitroglycerin and the neuromuscular blockade produced by gallamine, succinylcholine, d-tubocurarine, and pancuronium.
Topics: Animals; Cats; Diaphragm; Drug Synergism; Gallamine Triethiodide; In Vitro Techniques; Muscle Contra | 1980 |
Comparative effects of nitroprusside and nitroglycerin; actions on phasic and tonic components of arterial smooth muscle contraction.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Epinephrine; Ferricyanides; In Vitro Techniques; Muscle Co | 1980 |
Studies with isolated human coronary arteries. Some general observations, potential mediators of spasm, role of calcium antagonists.
Topics: Acetylcholine; Animals; Calcium; Cattle; Coronary Vessels; Diltiazem; Dogs; Ergonovine; Gallopamil; | 1980 |
Absence of metabolite formation during nitroglycerin-induced relaxation of isolated blood vessels.
Topics: Animals; Biotransformation; Dogs; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle | 1980 |
Actions of nitroglycerine on the membrane and mechanical properties of smooth muscles of the coronary artery of the pig.
Topics: Acetylcholine; Animals; Calcium; Coronary Vessels; Electric Stimulation; In Vitro Techniques; Membra | 1980 |
Effects of perhexiline on contractile response of rabbit aorta to norepinephrine and potassium.
Topics: Animals; Aorta, Thoracic; Drug Interactions; In Vitro Techniques; Muscle Contraction; Muscle, Smooth | 1980 |
Actions of nitroglycerine on smooth muscles of the guinea-pig and rat portal veins.
Topics: Animals; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscle, Smooth, | 1980 |
Spontaneous phasic activity of isolated human coronary arteries.
Topics: Adult; Calcium; Coronary Vessels; Ergonovine; Female; Humans; In Vitro Techniques; Male; Muscle Cont | 1980 |
Nitroglycerine and catecholamine actions on smooth muscle cells of the canine coronary artery.
Topics: Acetylcholine; Adenosine; Animals; Catecholamines; Coronary Vessels; Dogs; Female; In Vitro Techniqu | 1980 |
A comparison of the differential effects of nitroglycerin, nifedipine and papaverine on contractures induced in vascular and intestinal smooth muscle by potassium and lanthanum.
Topics: Animals; Calcium; Coronary Vessels; Dogs; Female; Intestines; Lanthanum; Male; Muscle Contraction; M | 1981 |
Tension response and 45Ca release in vascular smooth muscle incubated in Ca-free solution.
Topics: Animals; Calcium; Calcium Radioisotopes; Histamine; In Vitro Techniques; Muscle Contraction; Muscle, | 1981 |
Nitroglycerin for ergotism. Experimental studies in vitro and in migraine patients and treatment of an overt case.
Topics: Adult; Arteries; Blood Pressure; Ergotamine; Ergotism; Female; Humans; In Vitro Techniques; Migraine | 1982 |
Influence of trimetazidine, an antianginal drug, on isolated dog arteries and veins.
Topics: Animals; Diltiazem; Dinoprost; Dogs; Electric Stimulation; Female; In Vitro Techniques; Isoprotereno | 1982 |
Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels.
Topics: Administration, Cutaneous; Animals; Aorta, Thoracic; Binding Sites; Drug Tolerance; Glyburide; Heart | 1993 |
Responses to perivascular nerve stimulation of distal temporal arteries from dogs and monkeys.
Topics: Adrenergic alpha-Antagonists; Animals; Arginine; Dinoprost; Dogs; Drug Interactions; Electric Stimul | 1993 |
Tolerance of epicardial coronary endothelium and smooth muscle to hyperkalemia.
Topics: Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Coronary Vessels; Endothelium, Vasc | 1994 |
Nitrovasodilator-induced relaxation and tolerance development in porcine vena cordis magna: dependence on intact endothelium.
Topics: Animals; Arginine; Cysteine; Dinoprost; Drug Tolerance; Endothelium, Vascular; In Vitro Techniques; | 1994 |
Nitric oxide formation is involved in vagal inhibition of the stomach of the trout (Salmo gairdneri).
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Electric Stimulation; Female; Gastric Mucos | 1994 |
Evidence for a role of endothelin 1 and protein kinase C in nitroglycerin tolerance.
Topics: Alkaloids; Angiotensin II; Animals; Aorta, Thoracic; Drug Tolerance; Endothelins; Female; In Vitro T | 1995 |
Contribution of activation of K+ channels to glyceryl trinitrate-induced relaxation of rabbit aorta.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Apamin; Charybdotoxin; Cyclic GMP; En | 1995 |
Direct effects of smooth muscle relaxation and contraction on in vivo human brachial artery elastic properties.
Topics: Adult; Analysis of Variance; Biomechanical Phenomena; Brachial Artery; Compliance; Elasticity; Human | 1995 |
Effects of glyceryl trinitrate tolerance on vascular responsiveness to constrictor agents in bovine isolated coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cattle; Coronary Vessel | 1995 |
Discordant effects of dietary L-arginine on vascular structure and reactivity in hypercholesterolemic rabbits.
Topics: Acetylcholine; Analysis of Variance; Animals; Aorta, Abdominal; Arginine; Cholesterol; Cholesterol, | 1995 |
Pharmacological natures of caffeine-induced endothelium-dependent and -independent contraction in canine mesenteric artery.
Topics: Adenylyl Cyclases; Animals; Benzopyrans; Caffeine; Calcium; Calcium Channel Blockers; Colforsin; Cro | 1995 |
Investigation of postmortem functional changes in human cerebral arteries.
Topics: Adult; Aged; Autopsy; Bradykinin; Cerebral Arteries; Epoprostenol; Female; Humans; Male; Middle Aged | 1993 |
Interaction between hydralazine and nitrovasodilators in vascular smooth muscle.
Topics: Animals; Aorta, Thoracic; Drug Interactions; Drug Tolerance; Hydralazine; In Vitro Techniques; Isoni | 1993 |
The inhibitory mechanisms of nicorandil in isolated rat urinary bladder and femoral artery.
Topics: Acetylcholine; Animals; Benzopyrans; Cromakalim; Cyclic GMP; Electric Stimulation; Femoral Artery; G | 1995 |
Interaction between endothelin and vasodilators in the human internal mammary artery.
Topics: Endothelins; Female; Humans; In Vitro Techniques; Male; Mammary Arteries; Muscle Contraction; Muscle | 1994 |
The contribution of guanylate cyclase stimulation and K+ channel opening to nicorandil-induced vasorelaxation depends on the conduit vessel and on the nature of the spasmogen.
Topics: Animals; Aorta; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Male; Mesenteric Arteries | 1994 |
Endothelium-independent relaxation by 17-alpha-estradiol of pig coronary arteries.
Topics: Animals; Aorta, Thoracic; Arginine; Coronary Vessels; Endothelium, Vascular; Estradiol; Female; In V | 1994 |
Functional analysis of vascular dysfunction in cyclosporin treated rats.
Topics: Acetylcholine; Animals; Aorta; Arginine; Cyclic GMP; Cyclosporins; Endothelium, Vascular; In Vitro T | 1994 |
Tolerance to the vascular effect of a novel nitric oxide-donating vasodilator, FK409.
Topics: Animals; Antihypertensive Agents; Coronary Vessels; Cysteine; Dogs; Dose-Response Relationship, Drug | 1994 |
5-HT3 receptors do not mediate vagally-induced relaxation or contraction of the isolated stomach of the guinea-pig.
Topics: Animals; Dimethylphenylpiperazinium Iodide; Electric Stimulation; In Vitro Techniques; Male; Metoclo | 1994 |
Reduced contractile function after balloon denudation of rat carotid arteries.
Topics: Acetylcholine; Animals; Carotid Arteries; Catheterization; In Vitro Techniques; Male; Muscle Contrac | 1994 |
Reduced endothelium-dependent vasodilation by acetylcholine and bradykinin in isolated nitroglycerin-tolerant blood vessels.
Topics: Acetylcholine; Animals; Arginine; Bradykinin; Drug Tolerance; Endothelium, Vascular; In Vitro Techni | 1994 |
Involvement of nitric oxide in the inhibitory innervation of the human isolated colon.
Topics: Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Apamin; Arginine; Autonomic Nervous System; | 1993 |
Nitrate tolerance and aging in isolated rat aorta.
Topics: Aging; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Drug Tolerance; In Vitro Techniqu | 1993 |
Prejunctional modulation of the nitrergic innervation of the canine ileocolonic junction via potassium channels.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Autonomic Nervous System; Colon; Dogs; Electric Stim | 1993 |
Relationship between contraction and relaxation in human and rabbit corpus cavernosum.
Topics: Alprostadil; Animals; Humans; In Vitro Techniques; Linear Models; Male; Muscle Contraction; Muscle, | 1993 |
Synergistic effects of cyclic AMP-related vasodilators and the phosphatase inhibitor okadaic acid.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Bucladesine; Colforsin; Drug Synergism; Ethers, Cyclic; M | 1993 |
Vascular smooth muscle contains a depletable store of a vasodilator which is light-activated and restored by donors of nitric oxide.
Topics: Animals; Aorta, Thoracic; Endothelium, Vascular; In Vitro Techniques; Light; Male; Muscle Contractio | 1993 |
Putative, selective inhibitors of sarcoplasmic reticulum Ca+(+)-pump ATPase inhibit relaxation by nitroglycerin and atrial natriuretic factor of the rabbit aorta contracted by phenylephrine.
Topics: Adenosine Triphosphatases; Animals; Aorta; Atrial Natriuretic Factor; Calcium; Calcium-Transporting | 1993 |
Activation of ATP-dependent K+ channels enhances myocardial protection due to cold high potassium cardioplegia: a force-frequency relationship study.
Topics: Animals; Cold Temperature; Glyburide; Guinea Pigs; Heart; Heart Arrest, Induced; Ion Channel Gating; | 1995 |
Activation of guanylate cyclase in the guinea-pig trachea reduces contractile responses of the smooth muscle.
Topics: Acetylcholine; Animals; Ascorbic Acid; Carcinogens; Electric Stimulation; Guanylate Cyclase; Guinea | 1995 |
Diffuse esophageal spasm: a malfunction that involves nitric oxide?
Topics: Adolescent; Adult; Arginine; Esophageal Spasm, Diffuse; Esophagus; Female; Humans; Male; Manometry; | 1995 |
Association and cosegregation of stroke with impaired endothelium-dependent vasorelaxation in stroke prone, spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Basilar Artery; Blood Pressure; Cerebrovascular Disorders; | 1996 |
Chronic vitamin E treatment prevents defective endothelium-dependent relaxation in diabetic rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Dose-Response Relationship | 1995 |
Modulation of smooth muscle activity by nitric oxide in the human upper urinary tract.
Topics: Citrulline; Dose-Response Relationship, Drug; Humans; Kidney; Muscle Contraction; Muscle, Smooth; Ni | 1995 |
Regional differences in vasculotoxic effects of cyclosporin in rats.
Topics: Acetylcholine; Animals; Aorta; Carotid Arteries; Cyclosporine; Endothelium, Vascular; Immunosuppress | 1995 |
A novel nonanticoagulant heparin prevents vascular endothelial cell dysfunction during hyperdynamic sepsis.
Topics: Acetylcholine; Animals; Anticoagulants; Aorta; Cecum; Endothelium, Vascular; Heparin, Low-Molecular- | 1996 |
Pharmacological nature of TP receptor mediated contraction in human intrapulmonary artery.
Topics: Adult; Aged; Calcium; Colforsin; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Cont | 1996 |
Differential effects of diltiazem and nitroglycerin on cytosolic Ca2+ concentration and on force in the bovine ophthalmic artery.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Cattle; Cytosol; Diltiazem; Female; Fura-2; Ma | 1996 |
Contribution of collagen, elastin, and smooth muscle to in vivo human brachial artery wall stress and elastic modulus.
Topics: Adult; Blood Pressure; Brachial Artery; Collagen; Elasticity; Elastin; Humans; Injections, Intra-Art | 1996 |
Heterogeneity of glyceryl trinitrate response in isolated bovine coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bradykinin; Cattle; Cor | 1996 |
Acute amelioration of diabetic endothelial dysfunction with a derivative of the nitric oxide synthase cofactor, tetrahydrobiopterin.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Endothelium, Vascular; In | 1997 |
Myosin light chain kinase phosphorylation in nitrovasodilator induced swine carotid artery relaxation.
Topics: Aequorin; Animals; Calcium; Carotid Arteries; Cyclic AMP; Cyclic GMP; Histamine; Muscle Contraction; | 1997 |
Inhibition by singlet molecular oxygen of the vascular reactivity in rabbit mesenteric artery.
Topics: Acetylcholine; Animals; Catalase; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Fluorescent | 1997 |
Heterogeneity in the vasorelaxing effect of nicorandil on dog epicardial coronary arteries: comparison with other NO donors.
Topics: Animals; Atrial Natriuretic Factor; Benzopyrans; Coronary Vessels; Cromakalim; Cyclic GMP; Dogs; Fem | 1997 |
The vasodilator effects of clevidipine on human internal mammary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Calcium Channel B | 1997 |
Vasodilation profile of CD-832, a novel dihydropyridine derivative in rabbit aorta.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Calcium Channel Blockers; In Vitro Techniques; | 1997 |
Pancreatic transplantation reverses endothelial dysfunction in experimental diabetes mellitus.
Topics: Acetylcholine; Amino Acids; Animals; Aorta, Abdominal; Blood Glucose; Diabetes Mellitus, Experimenta | 1998 |
Accidental coin swallowing and sublingual nitroglycerin.
Topics: Esophagogastric Junction; Foreign Bodies; Humans; Muscle Contraction; Muscle, Smooth; Nitroglycerin | 1998 |
Endothelin-induced contractions in placental arteries is mediated by both ETA- and ETB-receptors.
Topics: Adult; Arteries; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Fem | 1998 |
Vasorelaxant effect of olprinone, an inhibitor of phosphodiesterase 3, on mesenteric small artery and vein of rabbits.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Caffeine; Calcium; Colforsin; Cyclic Nucleotide Phosph | 1998 |
Nitroglycerin-induced aortic relaxation mediated by calcium-activated potassium channel is markedly diminished in hypertensive rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Calcium; Charybdotoxin; Guanylate Cyclase; Hypertension; I | 1998 |
The role of nitric oxide in the development of opioid withdrawal induced by naloxone after acute treatment with mu- and kappa-opioid receptor agonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetylchol | 1998 |
Supersensitivity to serotonin- and histamine-induced arterial contraction following ovariectomy.
Topics: Acetylcholine; Adenosine; Animals; Aorta, Thoracic; Coronary Vessels; Dose-Response Relationship, Dr | 1998 |
Enhanced, unaltered and impaired nitric oxide-mediated endothelium-dependent relaxation in experimental diabetes mellitus: importance of disease duration.
Topics: Acetylcholine; Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibi | 1999 |
Effect of K+ channel openers, KRN2391 and Ki1769, and nitroglycerin on the urinary tract of rats in vivo.
Topics: Animals; Female; In Vitro Techniques; Muscle Contraction; Nitroglycerin; Potassium Channels; Pyridin | 1999 |
Effective improvement of the cerebral vasospasm after subarachnoid hemorrhage with low-dose nitroglycerin.
Topics: Administration, Cutaneous; Animals; Basilar Artery; Coronary Angiography; Hemodynamics; In Vitro Tec | 2000 |
[The effect of nitric oxide on the contractile activity of skinned preparations of the smooth muscles of the rat portal vein].
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Methylene Blue; M | 2000 |
Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells.
Topics: Animals; Female; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Nitroglycerin; Nitroprusside; Uter | 2000 |
Endothelin receptor antagonism does not prevent the development of in vivo glyceryl trinitrate tolerance in the rat.
Topics: Animals; Aorta, Thoracic; Binding, Competitive; Biotransformation; Blood Pressure; Cyclic GMP; Drug | 2000 |
YC-1 enhances the responsiveness of tolerant vascular smooth muscle to glyceryl trinitrate.
Topics: Animals; Aorta, Thoracic; Cyclic GMP; Drug Tolerance; Enzyme Activators; In Vitro Techniques; Indazo | 2001 |
HNS-32, a novel azulene-1-carboxamidine derivative, inhibits nifedipine-sensitive and -insensitive contraction of the isolated rabbit aorta.
Topics: Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; Calcium Channel Blockers; Colforsin; Endothelium, | 2001 |
Effects of radiation therapy on vascular responsiveness.
Topics: Acetylcholine; Animals; Aorta; Beta Particles; Bradykinin; Gamma Rays; In Vitro Techniques; Muscle C | 2001 |
Inhibitory effects of verapamil and nitroglycerin on contraction and cytosolic Ca2+ levels in cerebrovascular smooth muscle during chronic cerebral vasospasm.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Chronic Disease; Cytosol; Disease Models, Anima | 2001 |
The influence of nitric oxide donors on the responses to nitrergic nerve stimulation in the mouse duodenum.
Topics: Animals; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Enzyme Inhibitors; Ethylm | 2001 |
Identification of the enzymatic mechanism of nitroglycerin bioactivation.
Topics: Aldehyde Dehydrogenase; Animals; Aorta, Thoracic; Biotransformation; Cell Line; In Vitro Techniques; | 2002 |
The effect of sublingually administered nitroglycerin on the contraction of the human gallbladder.
Topics: Adolescent; Adult; Aged; Female; Gallbladder; Humans; Male; Middle Aged; Muscle Contraction; Muscle, | 1978 |
Effect of the ionophore, A23187, on contraction and relaxation of rat arteries and veins.
Topics: Animals; Anti-Bacterial Agents; Arteries; Blood Vessels; Calcimycin; Calcium; In Vitro Techniques; M | 1978 |
Effects of 2-nicotinamidoethyl nitrate (SG-75) on dog coronary artery and cat papillary muscle.
Topics: Animals; Calcium Chloride; Cats; Coronary Vessels; Dogs; Electric Stimulation; Female; Isoproterenol | 1979 |
Decreased vascular relaxation in hypertension.
Topics: Adenosine; Animals; Aorta, Thoracic; Bucladesine; Cyclic GMP; Female; Hypertension, Renal; Isoproter | 1976 |
Effect of isoprenaline and phenylephrine on the adenosine 3',5'-monophosphate content and mechanical activity of cold-stored and fresh taenia caecum from the guinea-pig.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Catecholamines; Cecum; Cold Tempera | 1977 |
Effects of sodium nitroprusside, nitroglycerin, and sodium azide on levels of cyclic nucleotides and mechanical activity of various tissues.
Topics: Animals; Azides; Cattle; Cyclic AMP; Cyclic GMP; Female; Ferricyanides; Guinea Pigs; Muscle Contract | 1977 |
Relationship between nitroglycerin, cyclic GMP and relaxation of vascular smooth muscle.
Topics: Animals; Cattle; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Mesenteric Arteries; Musc | 1979 |
Effects of isoproterenol on adrenergic constriction in vascular smooth muscle.
Topics: Animals; Carotid Arteries; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Nitroglycerin; N | 1977 |
Comparative effects of glyceryl trinitrate on venous and arterial smooth muscle in vitro; relevance to antianginal activity.
Topics: Angina Pectoris; Animals; Blood Vessels; Dogs; Drug Interactions; Femoral Artery; In Vitro Technique | 1977 |
Influence of reduction of preload and afterload by nitroglycerin on left ventricular diastolic pressure-volume relations and relaxation in man.
Topics: Adult; Blood Pressure; Blood Volume; Coronary Disease; Heart Ventricles; Hemodynamics; Humans; Male; | 1977 |
Effects of verapamil and nitroglycerin on contractile responses to potassium and noradrenaline in isolated human peripheral veins.
Topics: Adult; Aged; Culture Media; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; N | 1978 |
The relationship between age and relaxation of vascular smooth muscle in the rabbit and rat.
Topics: Aging; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Female; Isoproterenol; Male; Musc | 1976 |
Comparison of drug-induced responses of rabbit trachea and bronchus.
Topics: Aminophylline; Animals; Atropine; Bronchi; Carbachol; Dose-Response Relationship, Drug; Female; Hist | 1976 |
[Experments on the mechanism of action of vascular spasmolytic agents. I. Effect nitroprusside sodium, nitroglycerine, prenylamine and verapamil on the arrested potassium contracture of isolated coronary arteries].
Topics: Animals; Arteries; Cattle; Coronary Vessels; Muscle Contraction; Nitroglycerin; Nitroprusside; Paras | 1976 |
[Experiments on the mechanism of action of vascular spasmolytic agents. II. Action of nitroprusside sodium, nitroglycerin, prenylamine and verapamil on the lanthanum contracture of isolated coronary arteries].
Topics: Animals; Arteries; Cattle; Coronary Vessels; Lanthanum; Muscle Contraction; Nitroglycerin; Nitroprus | 1976 |
Nifedipine-resistant Ca(++)-induced contraction in tail artery of spontaneously hypertensive rats.
Topics: Animals; Arteries; Blood Pressure; Calcium; Cyclic GMP; Egtazic Acid; In Vitro Techniques; Male; Met | 1992 |
Prolonged exposure to catecholamines enhances sensitivity of smooth muscle relaxation induced by sodium nitroprusside and atriopeptin.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Cyclic GMP; Guanylate Cyclase; In Vitro Techniques; Male; | 1992 |
Inhibitory effects of glyceryl trinitrate on alpha-adrenoceptor mediated contraction in the human internal mammary artery.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Female; Humans | 1992 |
Comparative in vitro study of a series of organic nitroesters: unique biphasic concentration-effect curves for glyceryl trinitrate in isolated bovine arterial smooth muscle and lack of stereoselectivity for some glyceryl trinitrate analogues.
Topics: Animals; Cattle; In Vitro Techniques; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascu | 1992 |
Relaxant effects on iloprost in canine cerebral artery.
Topics: Animals; Basilar Artery; Cerebral Arteries; Dogs; Female; Iloprost; In Vitro Techniques; Male; Muscl | 1992 |
Inhibition of human internal mammary artery contractions. An in vitro study of vasodilators.
Topics: Adenosine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Isoproterenol; Mammary Art | 1992 |
Characteristics of the contractile response of rabbit aorta produced by cromakalim in calcium-free solution.
Topics: Animals; Aorta; Benzopyrans; Calcium; Colforsin; Cromakalim; Guanidines; Male; Microelectrodes; Mino | 1992 |
Assessment of changes in vasomotor tone in vivo using intravascular ultrasound.
Topics: Animals; Aorta; Arginine; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Este | 1992 |
Possibilities of the tolerance development to nipradilol and of the measurement of vascular glutathione content in isolated rat aorta.
Topics: Animals; Aorta, Thoracic; Drug Tolerance; Glutathione; In Vitro Techniques; Male; Muscle Contraction | 1992 |
Direct evidence for nitric oxide formation from glyceryl trinitrate during incubation with intact bovine pulmonary artery.
Topics: Animals; Carbon Dioxide; Cattle; In Vitro Techniques; Lung; Muscle Contraction; Muscle, Smooth, Vasc | 1992 |
[Changes in the reactivity of the vascular wall under the effect of ionizing radiation].
Topics: Acetylcholine; Animals; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Muscle Contractio | 1992 |
Effects of metabolic inhibitors on endothelium-dependent and endothelium-independent vasodilatation of rat and rabbit aorta.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Antimetabolites; Aorta, Thoracic; Bu | 1991 |
The mode of vasorelaxing action of melatonin in rabbit aorta.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta; Dinoprost; In Vitro Techniques; Male; Melatonin | 1991 |
Ouabain, Na(+)-free and K(+)-free solutions and relaxations to nitric oxide and nitrovasodilators.
Topics: Animals; Coronary Vessels; Dogs; Female; In Vitro Techniques; Isometric Contraction; Male; Muscle Co | 1991 |
Inhibition of coronary artery superoxide dismutase attenuates endothelium-dependent and -independent nitrovasodilator relaxation.
Topics: Acetylcholine; Animals; Cattle; Cells, Cultured; Coronary Vessels; Cyclic GMP; Ditiocarb; Endotheliu | 1991 |
Stimulative effect of sodium nitroprusside on peristaltic reflex in isolated guinea pig ileal segments.
Topics: Animals; Arginine; Cyclic GMP; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Methyl | 1991 |
Nicorandil: differential contribution of K+ channel opening and guanylate cyclase stimulation to its vasorelaxant effects on various endothelin-1-contracted arterial preparations. Comparison to aprikalim (RP 52891) and nitroglycerin.
Topics: Animals; Coronary Vessels; Endothelins; Endothelium, Vascular; Glyburide; Guanylate Cyclase; Heart; | 1991 |
Release and vascular activity of endothelium-derived relaxing factor in atherosclerotic rabbit aorta.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Aorta, Thoracic; Arteriosclerosis; Calcimycin; Cholesterol | 1990 |
Comparison of endothelium-dependent responses of monkey cerebral and temporal arteries.
Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcimycin; Cerebral Arteries | 1991 |
Protein kinase C-mediated contraction in rabbit aorta is inhibited by CD-349, a dihydropyridine derivative.
Topics: Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Calcium Channel Blockers; Cyclic AMP; Dihydropy | 1991 |
Nicorandil-induced vasorelaxation: functional evidence for K+ channel-dependent and cyclic GMP-dependent components in a single vascular preparation.
Topics: Animals; Calcium; Cyclic GMP; Drug Tolerance; Mesenteric Arteries; Methylene Blue; Muscle Contractio | 1991 |
Low level hyperlipidemia impairs endothelium-dependent relaxation of porcine coronary arteries by two mechanisms. Functional change in endothelium and impairment of endothelium-dependent relaxation by two mediators.
Topics: Animals; Bradykinin; Calcimycin; Cholesterol; Coronary Vessels; Endothelium, Vascular; Hyperlipidemi | 1991 |
Endothelin-1-induced phosphorylation of the 20-kDa myosin light chain and caldesmon in porcine coronary artery smooth muscle.
Topics: Animals; Calcium; Calmodulin; Calmodulin-Binding Proteins; Coronary Vessels; Endothelins; In Vitro T | 1991 |
Differential antagonism by glibenclamide of the relaxant effects of cromakalim, pinacidil and nicorandil on canine large coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arteries; Benzopyrans; | 1991 |
Effects of nitroglycerin on ATP-induced Ca(++)-mobilization, Ca(++)-activated K channels and contraction of cultured smooth muscle cells of porcine coronary artery.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Coronary Vessels; Cyclic | 1991 |
Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; In Vitro Techn | 1991 |
Influence of controlled hypotension by adenosine triphosphate or nitroglycerin on the neuromuscular blocking effect of atracurium in dogs.
Topics: Adenosine Triphosphate; Animals; Atracurium; Dogs; Drug Synergism; Female; Hindlimb; Hypotension, Co | 1991 |
Influence of glycerol trinitrate on contractions of isolated guinea pig tracheas induced by electrical field stimulation.
Topics: Airway Resistance; Animals; Culture Techniques; Dose-Response Relationship, Drug; Electric Stimulati | 1991 |
Airway blood flow modifies allergic airway smooth muscle contraction.
Topics: Acetylcholine; Airway Resistance; Allergens; Animals; Ascaris; Female; Mucous Membrane; Muscle Contr | 1991 |
Bioassay of nitric oxide released upon stimulation of non-adrenergic non-cholinergic nerves in the canine ileocolonic junction.
Topics: Animals; Aorta, Thoracic; Autonomic Nervous System; Colon; Dimethylphenylpiperazinium Iodide; Dogs; | 1991 |
Effect of tolerance to glyceryl trinitrate on vascular responses in conscious rabbits.
Topics: Administration, Cutaneous; Animals; Aorta, Thoracic; Consciousness; Drug Tolerance; Endothelium, Vas | 1991 |
Pertussis toxin inhibits endothelium-dependent relaxations evoked by fluoride.
Topics: Acetylcholine; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Coronary Vessels | 1990 |
Comparison of the direct effects of halothane and isoflurane on large and small coronary arteries isolated from dogs.
Topics: Adenosine; Animals; Coronary Vessels; Dogs; Female; Halothane; In Vitro Techniques; Isoflurane; Male | 1990 |
Effects of nitroglycerin on stable thromboxane A2 analogue-induced, nifedipine-resistant contraction in canine basilar artery.
Topics: Animals; Basilar Artery; Calcium; Coronary Vessels; Dogs; Muscle Contraction; Nifedipine; Nitroglyce | 1990 |
Different time course of atrial natriuretic factor-induced relaxation in rabbit aorta and portal vein.
Topics: Animals; Aorta, Thoracic; Atrial Natriuretic Factor; In Vitro Techniques; Muscle Contraction; Muscle | 1990 |
GABAA receptor-mediated stimulation of non-adrenergic non-cholinergic neurones in the dog ileocolonic junction.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Colon; Dogs; Electric Stimulation; Female; GABA Antag | 1990 |
[The dynamic changes in the functional characteristics of the vascular endothelium and smooth muscle cells under conditions of long-term hypercholesterolemia].
Topics: Acetylcholine; Animals; Aorta; Calcimycin; Chronic Disease; Diet, Atherogenic; Endothelium, Vascular | 1990 |
Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Aging; B | 1986 |
N-acetylcysteine does not modify nitroglycerin-induced tolerance in canine vascular rings.
Topics: Acetylcysteine; Animals; Dogs; Drug Interactions; Drug Tolerance; In Vitro Techniques; Muscle Contra | 1987 |
Development of a large fibromuscular intimal thickening does not impair endothelium-dependent relaxation in the rabbit carotid artery.
Topics: Animals; Calcimycin; Carotid Arteries; Endothelium; Male; Methacholine Chloride; Methacholine Compou | 1987 |
Effect of in vivo nitroglycerin therapy on endothelium-dependent and independent vascular relaxation and cyclic GMP accumulation in rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Cyclic GMP; Endothelium, Vascular; Histamine; Male; Muscle | 1987 |
Comparison of the inhibitory effects of nicorandil, nitroglycerin and isosorbide dinitrate on vascular smooth muscle of rabbit aorta.
Topics: Animals; Aorta; Calcium; Cyclic GMP; In Vitro Techniques; Ion Channels; Isosorbide Dinitrate; Male; | 1987 |
Nitroglycerin-sensitive and -resistant contractions mediated by receptor-operated calcium channels in rabbit ear artery.
Topics: Animals; Arteries; Ear; Histamine; In Vitro Techniques; Ion Channels; Muscle Contraction; Muscle, Sm | 1987 |
The effects of nicorandil on phasic contractions of isolated canine coronary artery.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calmodulin; Coronary Vessels; Dogs; Ergonov | 1987 |
Release of endothelium-derived relaxing factor is inhibited by 8-bromo-cyclic guanosine monophosphate.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aorta, Thoracic; Biological | 1988 |
Extraluminally applied acetylcholine and substance P on the release of EDRF.
Topics: Acetylcholine; Animals; Biological Factors; Dogs; Endothelium, Vascular; Female; Femoral Artery; Inf | 1989 |
Comparison of relaxation induced by glyceryl trinitrate, isosorbide dinitrate, and sodium nitroprusside in bovine airways.
Topics: Animals; Carbachol; Cattle; Dose-Response Relationship, Drug; Ferricyanides; In Vitro Techniques; Is | 1989 |
Synthetic nitrovasodilators are effective, in vitro, in relaxing penile tissue from impotent men: the findings and their implications.
Topics: Dose-Response Relationship, Drug; Erectile Dysfunction; Humans; In Vitro Techniques; Isosorbide Dini | 1989 |
Effects of magnesium on the tone of isolated human coronary arteries. Comparison with diltiazem and nitroglycerin.
Topics: Coronary Vasospasm; Coronary Vessels; Diltiazem; Female; Humans; In Vitro Techniques; Magnesium; Mal | 1989 |
Histamine relaxation of aortic rings from diabetic rats.
Topics: Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Diphenhydramine; Endothelium, Vascular; H | 1989 |
[Effects of hypercholesterolemia on the electrical and contractile properties of the blood vessel wall].
Topics: Acetylcholine; Animals; Arteriosclerosis; Endothelium, Vascular; Hypercholesterolemia; In Vitro Tech | 1989 |
Actions of a newly synthesized nitro-compound, E-4701, on rabbit vascular smooth muscles.
Topics: Acetylcholine; Animals; Calcium; Coronary Circulation; Dioxanes; Dioxins; Membrane Potentials; Mesen | 1989 |
Beta-migrating very low density lipoprotein attenuates endothelium-dependent relaxation in rabbit atherosclerotic aortas.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Aorta, Thoracic; Aortic Diseases; Arteriosclerosis; | 1989 |
Comparison of contractions to serotonin, carbamylcholine and prostaglandin F2 alpha in rat stomach fundus.
Topics: Animals; Carbachol; Diltiazem; Dinoprost; Gastric Fundus; Guanidines; In Vitro Techniques; Isoproter | 1989 |
[Two types of relaxation responses mediated by cyclic GMP in cerebral arteries].
Topics: Adult; Aged; Animals; Basilar Artery; Calcimycin; Cerebral Arteries; Child, Preschool; Cyclic GMP; D | 1989 |
Glyceryl trinitrate inhibits phosphatidylinositol hydrolysis and protein kinase C activity in bovine mesenteric artery.
Topics: Animals; Cattle; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol Phospha | 1988 |
Clinical pharmacology of vasodilator drugs.
Topics: Adrenergic alpha-Antagonists; Calcium Channel Blockers; Coronary Disease; Humans; Hydralazine; Hyper | 1985 |
Some actions of sodium nitroprusside and glyceryl trinitrate on guinea-pig isolated trachealis muscle.
Topics: Aminophylline; Animals; Ethacrynic Acid; Female; Ferricyanides; Guinea Pigs; In Vitro Techniques; Is | 1985 |
The relaxant effect of glyceryltrinitrate on isolated human peripheral vein and its relation to cyclic GMP metabolism.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Cyclic GMP; Dose-Response | 1986 |
Development of tolerance to glyceryl trinitrate in an isolated human peripheral vein and its relation to cyclic GMP metabolism.
Topics: Cyclic GMP; Dipyridamole; Drug Tolerance; Guanylate Cyclase; Humans; In Vitro Techniques; Muscle Con | 1986 |
Desensitization of guanylate cyclase in nitrate tolerance does not impair endothelium-dependent responses.
Topics: Animals; Aorta, Thoracic; Biological Factors; Cattle; Cells, Cultured; Cyclic GMP; Drug Tolerance; E | 1988 |
Effects of nicorandil on the rhythmic contractile response of isolated miniature pig coronary artery to 3,4-diaminopyridine: comparison with nitroglycerin.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Coronary Vasospasm; Coronary Vessels; Femal | 1986 |
Tetraethylammonium-induced contraction of rabbit coronary artery.
Topics: Animals; Arteries; Coronary Vessels; Ergonovine; Isoproterenol; Muscle Contraction; Muscle, Smooth, | 1988 |
Nitroglycerine- and isoprenaline-induced vasodilatation: assessment from the actions of cyclic nucleotides.
Topics: Animals; Bucladesine; Caffeine; Calcium; Cyclic AMP; Cyclic GMP; Drug Interactions; Female; In Vitro | 1985 |
Effect of glyceryltrinitrate and 8-Br-cGMP on tension and phosphorylase a activity in vascular smooth muscle.
Topics: Animals; Calcium; Cattle; Cyclic AMP; Cyclic GMP; Electric Stimulation; In Vitro Techniques; Isometr | 1985 |
Influence of the epithelium on responsiveness of guinea-pig isolated trachea to contractile and relaxant agonists.
Topics: Acetylcholine; Animals; Asthma; Autoradiography; Carbachol; Cimetidine; Colforsin; Dose-Response Rel | 1986 |
Nitroglycerin-induced desensitization of vascular smooth muscle may be mediated through cyclic GMP-disinhibition of phosphatidylinositol hydrolysis.
Topics: Animals; Aorta; Cyclic GMP; Drug Tolerance; Hydrolysis; Male; Muscle Contraction; Muscle, Smooth, Va | 1987 |
Studies on the effect of different inhibitors of arachidonic acid metabolism on glyceryltrinitrate-induced relaxation and cGMP elevation in bovine vascular tissue.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Vessels; Cattle; Cyclic GMP; In Vitro Techniques; Masopro | 1987 |
Comparative effects of diltiazem and glycerol trinitrate on isolated ureter and coronary artery of the dog.
Topics: Animals; Benzazepines; Calcium; Coronary Vessels; Diltiazem; Dogs; Female; Male; Muscle Contraction; | 1986 |
Atherosclerosis impairs endothelium-dependent vascular relaxation to acetylcholine and thrombin in primates.
Topics: Acetylcholine; Animals; Arteriosclerosis; Diet, Atherogenic; Dose-Response Relationship, Drug; Endot | 1986 |
Effects of nitroglycerin, dipyridamole, nifedipine, verapamil and diltiazem on canine coronary arterial rings contracted with 5-hydroxytryptamine and anoxia.
Topics: Animals; Arteries; Calcium; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Dipyridamole; Dog | 1986 |
Phorbol dibutyrate contractions in rabbit aorta: calcium dependence and sensitivity to nitrovasodilators and 8-BR-cyclic GMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Male; Muscle Contraction; Nifedipine; Nitr | 1986 |
Mode of vasorelaxing action of 5-[3-[[2-(3,4-dimethoxyphenyl)-ethyl]amino]-1-oxopropyl]-2,3,4,5- tetrahydro-1,5-benzothiazepine fumarate (KT-362), a new intracellular calcium antagonist.
Topics: Animals; Caffeine; Calcium Channel Blockers; Diltiazem; Egtazic Acid; Gallopamil; Lanthanum; Male; M | 1987 |
Vasodilator actions of TRK-100, a new prostaglandin I2 analogue.
Topics: Animals; Basilar Artery; Calcium; Dinoprost; Dogs; Epoprostenol; Female; In Vitro Techniques; Male; | 1986 |
[Biological effects of SIN-1 in the vascular wall].
Topics: Animals; Endothelium; Epoprostenol; Molsidomine; Muscle Contraction; Muscle, Smooth, Vascular; Nitro | 1987 |
A comparative study of glyceryl trinitrate biotransformation and glyceryl trinitrate induced relaxation in bovine pulmonary artery and vein.
Topics: Animals; Biotransformation; Cattle; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Musc | 1987 |
[Effects of calcium antagonists on intracellular calcium deposits].
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Diltiazem; Female; In Vitro Techniques; | 1987 |
Nitroglycerin-induced coronary vasodilatory responses in patients during isometric handgrip exercise.
Topics: Cardiac Catheterization; Coronary Circulation; Coronary Disease; Coronary Vessels; Hemodynamics; Hum | 1988 |
Studies on the effects of viprostol in isolated small blood vessels and thoracic aorta of the rat.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Basilar Artery; Blood Vessels; Dinoprostone; Dose | 1988 |
EDRF generation and release from perfused bovine pulmonary artery and vein.
Topics: Animals; Biological Products; Calcimycin; Cattle; In Vitro Techniques; Muscle Contraction; Muscle Re | 1988 |
Relaxation of isolated corpus cavernosum induced by smooth-muscle relaxant drugs. A comparative study.
Topics: Adult; Aged; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; | 1988 |
The effect of furosemide on vascular smooth muscle is influenced by plasma protein.
Topics: Animals; Dose-Response Relationship, Drug; Electric Stimulation; Furosemide; In Vitro Techniques; Mu | 1988 |
Abolition of spontaneous rhythmic contractions of isolated monkey coronary arteries by diltiazem, nifedipine, verapamil and nicorandil but not by nitroglycerin.
Topics: Animals; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Erythrocebus patas; Female; In Vitro | 1985 |
Effect of glyceryl trinitrate on the sphincter of Oddi motility and baseline pressure.
Topics: Adolescent; Adult; Ampulla of Vater; Common Bile Duct; Dilatation; Female; Humans; Male; Manometry; | 1985 |
[Adrenergic components of direct coronary and cardiac action of nitroglycerin].
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Coronary Vessels; Guinea Pigs; Heart | 1974 |
[Mechanism of nitroglycerine effect from the aspect of myocardial contractility. Experimental animal studies on the isolated human ventricular myocardium].
Topics: Adolescent; Adult; Angina Pectoris; Animals; Cats; Heart; Humans; In Vitro Techniques; Middle Aged; | 1973 |
Sulfhydryl requirement for relaxation of vascular smooth muscle.
Topics: Animals; Aorta, Thoracic; Blood Vessels; Cysteine; Dose-Response Relationship, Drug; Ethacrynic Acid | 1973 |
Supersensitivity to pentagastrin in diffuse oesophageal spasm.
Topics: Adult; Atropine; Esophageal Achalasia; Esophagogastric Junction; Esophagus; Humans; Injections, Intr | 1974 |
Effects of dipyridamole on neurogenic and non-neurogenic dilator responses of arterial smooth muscle.
Topics: Acetylcholine; Animals; Arteries; Blood Pressure; Depression, Chemical; Dipyridamole; Electric Stimu | 1974 |
The effects of theophylline, diazoxide and imidazole on isoproterenol-induced inhibition of the rabbit ileum.
Topics: Animals; Cyclic AMP; Diazoxide; Ileum; Imidazoles; In Vitro Techniques; Isoproterenol; Muscle Contra | 1969 |
Responses of isolated human uterine arteries to vasoactive drugs.
Topics: Adult; Aged; Angiotensin II; Arteries; Female; Humans; Isoproterenol; Middle Aged; Muscle Contractio | 1971 |
The prevention of isoproterenol desensitization and isoproterenol reversal.
Topics: Aminophylline; Angiotensin II; Animals; Aorta; Bromine; Desensitization, Immunologic; Drug Interacti | 1972 |
A possible etiology of contractility impairment of vascular smooth muscle from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Barium; Blood Pressure; Calcium; Cobalt; Hypertension; In | 1973 |
Age-related changes in vascular responsiveness to cyclic nucleotides and contractile agonists.
Topics: Aging; Animals; Aorta, Thoracic; Benzyl Compounds; Bucladesine; Cyclic AMP; Cyclic GMP; Dose-Respons | 1974 |
Effect of catecholamines on smooth muscle motility and phosphorylase activity.
Topics: Animals; Epinephrine; Ethanolamines; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Methys | 1966 |
Effects of glyceryl trinitrate on the aortic strip of rabbits.
Topics: Animals; Aorta; Hydrogen-Ion Concentration; In Vitro Techniques; Muscle Contraction; Nitroglycerin; | 1967 |
Effect of certain drugs on perfused human placenta. IX. Mode of action of angiotensin.
Topics: Angiotensin II; Blood Vessels; Constriction; Dipyridamole; Ethanolamines; Female; Humans; Hydralazin | 1969 |
An evaluation of the vasodilation produced by mephentermine and certain other sympathomimetic amines.
Topics: Animals; Arteries; Atropine; Blood Flow Velocity; Chemical Phenomena; Chemistry; Dextroamphetamine; | 1970 |
Extent of carotid sinus regulation of the myocardial contractile state in conscious dogs.
Topics: Animals; Atropine; Blood Pressure; Cardiac Output; Carotid Arteries; Carotid Sinus; Constriction; Do | 1972 |
[Physiology of the coronary circulation as a basis for evaluating coronary dilators].
Topics: Animals; Blood Pressure; Carbon Dioxide; Coronary Circulation; Coronary Vessels; Disease Models, Ani | 1972 |
[Electromechanical uncoupling of vascular smooth muscle as the basic principle of coronary dilatation by 4-(2'-nitrophenyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester (BAY a 1040, Nifedipine). 1. The significance of Ca ++ ions f
Topics: Animals; Calcium; Cattle; Coronary Vessels; Dicarboxylic Acids; Female; Membrane Potentials; Muscle | 1972 |
Evidence that phentolamine acts centrally to increase the contractile force of the heart.
Topics: Animals; Blood Pressure; Carotid Arteries; Dogs; Female; Ganglia, Autonomic; Heart; Heart Rate; Hexa | 1972 |
Regulation of cardiac output after administration of isoproterenol and ouabain: interactions of systolic impedance and contractility.
Topics: Animals; Blood Pressure; Calcium Chloride; Cardiac Output; Coronary Circulation; Dogs; Heart Rate; I | 1972 |
Nitroglycerin on the carotid artery and femoral artery of the dog.
Topics: Animals; Blood Pressure; Carotid Arteries; Denervation; Dogs; Femoral Artery; Muscle Contraction; Ni | 1972 |
Effects of adenosine on isolated coronary vascular smooth muscle.
Topics: Adenosine; Animals; Coronary Vessels; Dilatation; Isoproterenol; Muscle Contraction; Muscle, Smooth; | 1972 |
[Mechanism of nitroglycerin effect from the aspect of myocardial contractibility: studies in the isolated human ventricular muscle].
Topics: Adolescent; Adult; Angina Pectoris; Heart; Humans; Middle Aged; Muscle Contraction; Myocardium; Nitr | 1972 |
Influence of coronary blood flow on left ventricular contractility and stiffness.
Topics: Animals; Coronary Circulation; Coronary Vessels; Dogs; Elasticity; Heart; Heart Function Tests; Musc | 1972 |
Effects of vasodilators on the isolated taenia coli of the guinea-pig.
Topics: Aminophylline; Animals; Calcium; Cell Membrane; Electrophysiology; Epinephrine; Guinea Pigs; In Vitr | 1967 |
Tolerance towards glyceryltrinitrate (trinitrin) in rabbits.
Topics: Animals; Aorta; Blood Pressure; Depression, Chemical; Drug Tolerance; Muscle Contraction; Muscle, Sm | 1968 |
[Significance of the a-wave for the evaluation of end-diastolic filling of the ventricle. Apex-cardiographic studies on subjects with coronary disease and with normal hearts].
Topics: Cardiac Output; Exercise Test; Female; Heart Ventricles; Humans; Kinetocardiography; Male; Middle Ag | 1968 |
Cardiovascular effects of glyceryldinitrates as compared to glyceryltrinitrate.
Topics: Animals; Aorta; Blood Pressure; Dogs; Guinea Pigs; Hindlimb; Muscle Contraction; Nitroglycerin; Perf | 1968 |
Smooth muscle relaxants: dissociation between resting membrane potential and resting tension in rat myometrium.
Topics: Animals; Catecholamines; Epinephrine; Female; In Vitro Techniques; Isoproterenol; Membrane Potential | 1969 |
A comparison of the effects of various smooth muscle relaxants on the electrical and mechanical activity of rat uterus.
Topics: Action Potentials; Animals; Calcium; Cell Membrane; Electricity; Epinephrine; Female; In Vitro Techn | 1969 |
[Physiology of the coronary circulation as a basis for evaluation of coronary dilators].
Topics: Animals; Aorta; Blood Pressure; Coronary Vessels; Depression, Chemical; Dogs; Guinea Pigs; Heart; He | 1969 |
[Action of nitroglycerin and intravenous injections of papaverine on the contractile function of the heart in patients with coronary circulatory disorders].
Topics: Adult; Aged; Coronary Disease; Female; Heart; Humans; Hypertension; Injections, Intravenous; Male; M | 1969 |
[Study of the effect of nitroglycerin on the hemodynamics and contractile function of6the myocardium using electrokymography].
Topics: Blood Pressure; Cardiac Output; Coronary Disease; Electrokymography; Heart; Heart Rate; Hemodynamics | 1969 |
Cardiovascular pharmacology of perhexiline.
Topics: Amidohydrolases; Animals; Blood Flow Velocity; Blood Pressure; Cardiac Output; Cardiovascular System | 1970 |
Effects of nitroglycerin (trinitrin) on vascular smooth muscle.
Topics: Acetylcholine; Animals; Aorta; Blood Flow Velocity; Blood Pressure; Blood Vessels; Constriction; Dog | 1970 |
Effects of coronary blood flow and perfusion pressure on left ventricular contractility in dogs.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Coronary Vessels; Dogs; Female; Male; Muscle Contracti | 1970 |
[Studies on inotropic actions of nitroglycerol on isolated ventricular muscle].
Topics: Animals; Cats; Heart Ventricles; In Vitro Techniques; Muscle Contraction; Nitroglycerin; Papillary M | 1971 |
Effect of nitroglycerin at different degrees of contraction of the rabbit aortic strip.
Topics: Animals; Aorta; Ions; Muscle Contraction; Nitroglycerin; Norepinephrine; Rabbits | 1971 |
[Aspects of the inotropic effects of nitroglycerin on the myocardium. Studies on the isolated human atrial and ventricular myocardium].
Topics: Angina Pectoris; Heart; Heart Atria; Heart Ventricles; Humans; Muscle Contraction; Nitroglycerin | 1971 |
Hemodynamic effects of nitroglycerin and amyl nitrite in the conscious dog.
Topics: Amyl Nitrite; Animals; Aorta, Thoracic; Blood Pressure; Cardiac Catheterization; Cardiac Output; Car | 1971 |
[Action mechanism of nitroglycerin: studies on the inotropic effect of nitroglycerin on the isolated human ventricular myocardium].
Topics: Heart Rate; Heart Ventricles; Humans; Muscle Contraction; Nitroglycerin; Papillary Muscles | 1971 |
[Contractile capacity of the myocardium in workers subjected to prolonged exposures of small concentrations of carbon monoxide].
Topics: Adult; Carbon Monoxide; Carbon Monoxide Poisoning; Chemical Industry; Heart; Heart Function Tests; H | 1971 |