nitroglycerin has been researched along with Migraine with Aura in 8 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Migraine with Aura: A subtype of migraine disorder, characterized by recurrent attacks of reversible neurological symptoms (aura) that precede or accompany the headache. Aura may include a combination of sensory disturbances, such as blurred VISION; HALLUCINATIONS; VERTIGO; NUMBNESS; and difficulty in concentrating and speaking. Aura is usually followed by features of the COMMON MIGRAINE, such as PHOTOPHOBIA; PHONOPHOBIA; and NAUSEA. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In contrast to patients with migraine with aura (MA) and migraine without aura (MO), most patients with familial hemiplegic migraine (FHM) do not report migraine-like attacks after pharmacologic provocation with glyceryl trinitrate (GTN), a donor of nitric oxide." | 1.36 | Coexisting typical migraine in familial hemiplegic migraine. ( Ashina, M; Hansen, JM; Olesen, J; Thomsen, LL, 2010) |
| "In each group, a migraine was induced using a glyceryl trinitrate (GTN) infusion." | 1.33 | A PET study exploring the laterality of brainstem activation in migraine using glyceryl trinitrate. ( Afridi, SK; Frackowiak, RS; Friston, KJ; Goadsby, PJ; Kaube, H; Lee, L; Matharu, MS, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hansen, JM | 3 |
| Thomsen, LL | 4 |
| Olesen, J | 4 |
| Ashina, M | 3 |
| Afridi, SK | 1 |
| Matharu, MS | 1 |
| Lee, L | 1 |
| Kaube, H | 2 |
| Friston, KJ | 1 |
| Frackowiak, RS | 1 |
| Goadsby, PJ | 2 |
| Afridi, S | 1 |
| Marconi, R | 1 |
| Casari, G | 1 |
| Christiansen, I | 1 |
| Daugaard, D | 1 |
| Ulrich, V | 1 |
| Mitchell, GK | 1 |
| Bánk, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neuroimaging Studies of Chronic Primary Headaches Using Positron Emission Tomography and Magnetic Resonance Imaging[NCT01741246] | 78 participants (Actual) | Observational | 2011-09-30 | Completed | |||
| A Phase 2a Study of the Safety and Effectiveness of NXN-188 for the Acute Treatment of Migraine Attacks With Aura[NCT00877838] | Phase 2 | 40 participants (Anticipated) | Interventional | 2009-05-31 | Recruiting | ||
| CGRP-induced Headache in Patients With Familial Hemiplegic Migraine, Migraine With Aura and Healthy Controls[NCT00687947] | 30 participants (Anticipated) | Interventional | 2008-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for nitroglycerin and Migraine with Aura
| Article | Year |
|---|---|
Familial hemiplegic migraine type 1 shows no hypersensitivity to nitric oxide.
Topics: Adult; Cyclic GMP; Female; Humans; Male; Middle Aged; Migraine with Aura; Nitric Oxide; Nitroglyceri | 2008 |
Glyceryl trinitrate induces attacks of migraine without aura in sufferers of migraine with aura.
Topics: Adult; Analgesics; Female; Hemodynamics; Humans; Male; Migraine with Aura; Migraine without Aura; Ni | 1999 |
6 other studies available for nitroglycerin and Migraine with Aura
| Article | Year |
|---|---|
Coexisting typical migraine in familial hemiplegic migraine.
Topics: Adult; Aged; Analgesics; Female; Humans; Male; Middle Aged; Migraine Disorders; Migraine with Aura; | 2010 |
A PET study exploring the laterality of brainstem activation in migraine using glyceryl trinitrate.
Topics: Adult; Aged; Brain Stem; Female; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Mig | 2005 |
Occipital activation in glyceryl trinitrate induced migraine with visual aura.
Topics: Cerebrovascular Circulation; Humans; Infusions, Intravenous; Male; Middle Aged; Migraine with Aura; | 2005 |
Familial hemiplegic migraine type 2 does not share hypersensitivity to nitric oxide with common types of migraine.
Topics: Adult; Blood Flow Velocity; Blood Pressure; Cerebrovascular Circulation; Cyclic GMP; Female; Genotyp | 2008 |
Nitroglycerine by inhaler as treatment for migraine causing cerebral ischaemia.
Topics: Administration, Inhalation; Adult; Female; Humans; Ischemic Attack, Transient; Migraine with Aura; N | 1999 |
Migraine with aura after administration of sublingual nitroglycerin tablets.
Topics: Administration, Sublingual; Angina Pectoris; Animals; Humans; Male; Middle Aged; Migraine with Aura; | 2001 |