nitroglycerin has been researched along with Metabolic Syndrome in 7 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin improves both endothelial function and insulin resistance in patients with MS." | 9.11 | Metformin improves endothelial function in patients with metabolic syndrome. ( Cornoldi, A; Fini, M; Mercuro, G; Rosano, GM; Vitale, C; Volterrani, M, 2005) |
| "Metformin improves both endothelial function and insulin resistance in patients with MS." | 5.11 | Metformin improves endothelial function in patients with metabolic syndrome. ( Cornoldi, A; Fini, M; Mercuro, G; Rosano, GM; Vitale, C; Volterrani, M, 2005) |
| " Future studies should pay attention to the delicate balance between sufficient dosing and timely normalization of plasma haem levels." | 1.43 | Vascular and metabolic effects of the haem oxygenase-1 inducer haem arginate in subjects with the metabolic syndrome: A translational cross-over study. ( Bilos, A; Dekker, D; Dorresteijn, MJ; Pennings, SW; Peters, WH; Smits, P; Wagener, FA, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dekker, D | 1 |
| Dorresteijn, MJ | 1 |
| Peters, WH | 1 |
| Bilos, A | 1 |
| Pennings, SW | 1 |
| Wagener, FA | 1 |
| Smits, P | 1 |
| Kovaite, M | 1 |
| Petrulioniene, Z | 1 |
| Ryliskyte, L | 1 |
| Badariene, J | 1 |
| Dzenkeviciute, V | 1 |
| Cypiene, A | 1 |
| Laucevicius, A | 1 |
| Polena, S | 1 |
| Gintautas, J | 1 |
| Hamdy, O | 1 |
| Ledbury, S | 1 |
| Mullooly, C | 1 |
| Jarema, C | 1 |
| Porter, S | 1 |
| Ovalle, K | 1 |
| Moussa, A | 1 |
| Caselli, A | 1 |
| Caballero, AE | 1 |
| Economides, PA | 1 |
| Veves, A | 1 |
| Horton, ES | 1 |
| Kelly, AS | 1 |
| Wetzsteon, RJ | 1 |
| Kaiser, DR | 1 |
| Steinberger, J | 1 |
| Bank, AJ | 1 |
| Dengel, DR | 1 |
| Vitale, C | 1 |
| Mercuro, G | 1 |
| Cornoldi, A | 1 |
| Fini, M | 1 |
| Volterrani, M | 1 |
| Rosano, GM | 1 |
| Sorensen, MB | 1 |
| Franks, S | 1 |
| Robertson, C | 1 |
| Pennell, DJ | 1 |
| Collins, P | 1 |
| Ghiadoni, L | 1 |
| Penno, G | 1 |
| Giannarelli, C | 1 |
| Plantinga, Y | 1 |
| Bernardini, M | 1 |
| Pucci, L | 1 |
| Miccoli, R | 1 |
| Taddei, S | 1 |
| Salvetti, A | 1 |
| Del Prato, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of High Intensity Interval Exercise on Inflammation and Endothelial Function in Children & Adolescents With Obesity[NCT01821313] | 43 participants (Actual) | Interventional | 2012-09-30 | Completed | |||
| Exercise Dose and Metformin for Vascular Health in Adults With Metabolic Syndrome[NCT03355469] | Phase 2/Phase 3 | 80 participants (Anticipated) | Interventional | 2017-08-07 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for nitroglycerin and Metabolic Syndrome
| Article | Year |
|---|---|
Inflammation, insulin, and endothelial function in overweight children and adolescents: the role of exercise.
Topics: Adolescent; Blood Glucose; Body Mass Index; C-Reactive Protein; Child; Cholesterol; Endothelium, Vas | 2004 |
Metformin improves endothelial function in patients with metabolic syndrome.
Topics: Brachial Artery; Endothelium, Vascular; Female; Homeostasis; Humans; Hypoglycemic Agents; Image Proc | 2005 |
5 other studies available for nitroglycerin and Metabolic Syndrome
| Article | Year |
|---|---|
Vascular and metabolic effects of the haem oxygenase-1 inducer haem arginate in subjects with the metabolic syndrome: A translational cross-over study.
Topics: Acetylcholine; Adult; Aged; Arginine; Bilirubin; Cross-Over Studies; Endothelium, Vascular; Female; | 2016 |
Systemic assessment of arterial wall structure and function in metabolic syndrome.
Topics: Adult; Aged; Arteries; Atherosclerosis; Carotid Arteries; Dilatation; Endothelium, Vascular; Female; | 2007 |
Lifestyle modification improves endothelial function in obese subjects with the insulin resistance syndrome.
Topics: Blood Flow Velocity; Blood Pressure; Body Mass Index; Brachial Artery; Endothelium, Vascular; Exerci | 2003 |
Severe endothelial dysfunction in young women with polycystic ovary syndrome is only partially explained by known cardiovascular risk factors.
Topics: Adult; Brachial Artery; Case-Control Studies; Endothelium, Vascular; Female; Humans; Linear Models; | 2006 |
Metabolic syndrome and vascular alterations in normotensive subjects at risk of diabetes mellitus.
Topics: Adult; Arteries; Blood Flow Velocity; Blood Pressure; Brachial Artery; Carotid Artery, Common; Cross | 2008 |