nitroglycerin has been researched along with Marfan Syndrome in 3 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Marfan Syndrome: An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome (type 1) is associated with mutations in the gene encoding FIBRILLIN-1 (FBN1), a major element of extracellular microfibrils of connective tissue. Mutations in the gene encoding TYPE II TGF-BETA RECEPTOR (TGFBR2) are associated with Marfan syndrome type 2.
Excerpt | Relevance | Reference |
---|---|---|
" Measurements were taken during hand hyperemia (a stimulus for endothelium-derived nitric oxide [NO] release in the upstream brachial artery) and after sublingual administration of the endothelium-independent vasodilator nitroglycerin." | 3.70 | Endothelial function in Marfan syndrome: selective impairment of flow-mediated vasodilation. ( Bellamy, MF; Brownlee, M; Davies, S; Goodfellow, J; Lewis, MJ; Ramsey, MW; Stuart, AG; Wilson, DG; Wilson, JF, 1999) |
"The antenatal diagnosis of aortic dissection carries a grave prognosis." | 1.39 | Successful management of aortic dissection in a patient with Marfan syndrome during pregnancy. ( Chang, CY; Chen, PH; Lam, CW; Yang, JM, 2013) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Chang, CY | 1 |
Yang, JM | 1 |
Lam, CW | 1 |
Chen, PH | 1 |
Payne, RA | 1 |
Hilling-Smith, RC | 1 |
Webb, DJ | 1 |
Maxwell, SR | 1 |
Denvir, MA | 1 |
Wilson, DG | 1 |
Bellamy, MF | 1 |
Ramsey, MW | 1 |
Goodfellow, J | 1 |
Brownlee, M | 1 |
Davies, S | 1 |
Wilson, JF | 1 |
Lewis, MJ | 1 |
Stuart, AG | 1 |
3 other studies available for nitroglycerin and Marfan Syndrome
Article | Year |
---|---|
Successful management of aortic dissection in a patient with Marfan syndrome during pregnancy.
Topics: Adult; Aortic Aneurysm; Aortic Dissection; Blood Pressure; Calcium Channel Blockers; Coronary Angiog | 2013 |
Augmentation index assessed by applanation tonometry is elevated in Marfan Syndrome.
Topics: Adolescent; Adult; Blood Pressure; Carotid Arteries; Case-Control Studies; Echocardiography; Elastic | 2007 |
Endothelial function in Marfan syndrome: selective impairment of flow-mediated vasodilation.
Topics: Acetylcholine; Adolescent; Adult; Brachial Artery; Bradykinin; Child; Endothelium, Vascular; Female; | 1999 |