nitroglycerin has been researched along with Left Ventricular Hypertrophy in 22 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether limitation of left ventricular (LV) hypertrophy with angiotensin-converting enzyme inhibition after myocardial infarction (MI) is associated with improved systolic and diastolic function, quantitative two-dimensional echocardiograms and Doppler of 40 patients, who were randomized on day 3 after a first Q-wave anterior MI to receive therapy with captopril (12." | 5.08 | Limitation of left ventricular hypertrophy and dysfunction by ACE inhibition after anterior Q-wave myocardial infarction. ( Humen, DP; Jugdutt, BI, 1998) |
| "In 42 unmedicated patients with hypertension and electrocardiographic left ventricular hypertrophy, we measured the following: 24-h ambulatory blood pressure (BP), minimal forearm vascular resistance (MFVR) by plethysmography, intima-media cross-sectional area of the common carotid arteries (IMA), FMD, and nitroglycerin-induced dilatation (NID) in the brachial artery by ultrasound." | 3.71 | Vasodilatory capacity and vascular structure in long-standing hypertension: a LIFE substudy. Losartan Intervention For Endpoint-Reduction in Hypertension. ( Aalkjaer, C; Dige-Petersen, H; Ibsen, H; Olsen, MH; Rokkedal, J; Wachtell, K, 2002) |
| "With carvedilol treatment, LVMI was lower (p<0." | 2.75 | Effect of carvedilol on coronary flow reserve in patients with hypertensive left-ventricular hypertrophy. ( Mei, Z; Xiaozhen, H; Yu, S; Yun, Z, 2010) |
| " A dose-response curve was obtained with nitroglycerin (30, 90, and 150 microg) in 11 patients and sodium nitroprusside (1, 2, and 4 microg/min) in 6." | 2.69 | Effect of NO donors on LV diastolic function in patients with severe pressure-overload hypertrophy. ( Hess, OM; Jiang, Z; Kaufmann, PA; Mandinov, L; Matter, CM; Vassalli, G, 1999) |
| " Several randomized studies have demonstrated that long-term administration of converting enzyme inhibitors not only reduces left ventricular enlargement but also lowers morbidity and mortality after myocardial infarction." | 2.39 | [Remodeling of the left ventricle following myocardial infarction: physiopathology and prevention]. ( Lerch, R; Ricou, F, 1994) |
| "10%), prevalence of aortic regurgitation (30% vs." | 1.35 | High prevalence of subclinical cardiovascular abnormalities in patients with systemic lupus erythematosus in spite of a very low clinical damage index. ( Celentano, A; Di Minno, MN; Lupo, T; Migliaresi, P; Orefice, M; Palmieri, V; Valentini, G, 2009) |
| "Myocardial ischemia is associated with impaired endothelium-independent vasodilation of resistance coronary arteries and increased minimal coronary resistance." | 1.32 | Contribution of increased minimal coronary resistance and attenuated vascular adaptive remodeling to myocardial ischemia in patients with systemic hypertension and ventricular hypertrophy. ( Fukudome, T; Hamasaki, S; Ishida, S; Kataoka, T; Minagoe, S; Mizoguchi, E; Ninomiya, Y; Okui, H; Otsuji, Y; Saihara, K; Shinsato, T; Tei, C, 2004) |
| "A pig model of myocardial hibernation of 24 hours to 7 days was created through severe left anterior descending coronary artery stenosis with coronary flow reductions of approximately 40%, producing severe regional left ventricular dysfunction but no infarction in seven pigs." | 1.30 | Nitroglycerin enhances the ability of dobutamine stress echocardiography to detect hibernating myocardium. ( Chen, C; Chen, L; Gillam, L; Ma, L; Waters, DD, 1997) |
| "Because left ventricular hypertrophy (LVH) is also associated with subendocardial hypoperfusion during exercise, this study tested the hypothesis that alterations of NO availability can similarly influence subendocardial blood flow in the hypertrophied heart." | 1.30 | Effect of NO on transmural distribution of blood flow in hypertrophied left ventricle during exercise. ( Bache, RJ; Duncker, DJ; Ishibashi, Y; Traverse, JH, 1999) |
| " The dose-response relation of intracoronary nitroglycerin was assessed in 14 patients (7 control subjects and 7 patients with aortic stenosis [study A]) using quantitative coronary angiography." | 1.29 | Reduced epicardial coronary vasodilator capacity in patients with left ventricular hypertrophy. ( Boj, H; Hess, OM; Jakob, M; Kaufmann, P; Kiowski, W; Vassalli, G; Villari, B, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (59.09) | 18.2507 |
| 2000's | 7 (31.82) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Palmieri, V | 1 |
| Migliaresi, P | 1 |
| Orefice, M | 1 |
| Lupo, T | 1 |
| Di Minno, MN | 1 |
| Valentini, G | 1 |
| Celentano, A | 1 |
| Xiaozhen, H | 1 |
| Yun, Z | 1 |
| Mei, Z | 1 |
| Yu, S | 1 |
| Bartolomucci, F | 1 |
| De Michele, M | 1 |
| Kozàkovà, M | 1 |
| Cipriani, F | 1 |
| Polemio, F | 1 |
| Palombo, C | 1 |
| Olsen, MH | 2 |
| Wachtell, K | 2 |
| Hermann, KL | 1 |
| Bella, JN | 1 |
| Dige-Petersen, H | 2 |
| Rokkedal, J | 2 |
| Ibsen, H | 2 |
| Kataoka, T | 1 |
| Hamasaki, S | 1 |
| Ishida, S | 1 |
| Saihara, K | 1 |
| Okui, H | 1 |
| Fukudome, T | 1 |
| Shinsato, T | 1 |
| Mizoguchi, E | 1 |
| Ninomiya, Y | 1 |
| Otsuji, Y | 1 |
| Minagoe, S | 1 |
| Tei, C | 1 |
| Vavuranakis, M | 1 |
| Rigopoulos, A | 1 |
| Vaina, S | 1 |
| Chrysohoou, C | 1 |
| Toutouzas, K | 1 |
| Stamatopoulos, I | 1 |
| Stefanadis, C | 1 |
| Seet, RC | 1 |
| Lim, EC | 1 |
| Mohler, ER | 1 |
| O'Hare, K | 1 |
| Darze, ES | 1 |
| Townsend, RR | 1 |
| Bridges, CR | 1 |
| Keane, MG | 1 |
| Sürig, M | 2 |
| Faber, L | 2 |
| Ylinen, T | 2 |
| Michalowski, Z | 1 |
| Klempt, HW | 2 |
| Vassalli, G | 2 |
| Kaufmann, P | 1 |
| Villari, B | 1 |
| Jakob, M | 1 |
| Boj, H | 1 |
| Kiowski, W | 1 |
| Hess, OM | 2 |
| Lerch, R | 1 |
| Ricou, F | 1 |
| Dumitriu, M | 1 |
| Schäfers, S | 1 |
| Kostic, N | 1 |
| Jugdutt, BI | 2 |
| Khan, MI | 1 |
| Ma, L | 1 |
| Chen, L | 1 |
| Gillam, L | 1 |
| Waters, DD | 1 |
| Chen, C | 1 |
| Ghaleh, B | 1 |
| Hittinger, L | 1 |
| Kim, SJ | 1 |
| Kudej, RK | 1 |
| Iwase, M | 1 |
| Uechi, M | 1 |
| Berdeaux, A | 1 |
| Bishop, SP | 1 |
| Vatner, SF | 1 |
| Pratt, CM | 1 |
| Mahmarian, JJ | 1 |
| Morales-Ballejo, H | 1 |
| Casareto, R | 1 |
| Moyé, LA | 1 |
| Humen, DP | 1 |
| Duncker, DJ | 1 |
| Traverse, JH | 1 |
| Ishibashi, Y | 1 |
| Bache, RJ | 1 |
| Matter, CM | 1 |
| Mandinov, L | 1 |
| Kaufmann, PA | 1 |
| Jiang, Z | 1 |
| Schunkert, H | 1 |
| Orzechowski, HD | 1 |
| Böcker, W | 1 |
| Meier, R | 1 |
| Riegger, GA | 1 |
| Paul, M | 1 |
| Aalkjaer, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Triple-Blind, Parallel Study to Investigate the Effect of Losartan Versus Atenolol on the Reduction of Morbidity and Mortality in Hypertensive Patients With Left Ventricular Hypertrophy[NCT00338260] | Phase 3 | 496 participants (Actual) | Interventional | 1995-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nitroglycerin and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
[Remodeling of the left ventricle following myocardial infarction: physiopathology and prevention].
Topics: Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertrophy, Left Ventricular; Myocardial Infarcti | 1994 |
6 trials available for nitroglycerin and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Effect of carvedilol on coronary flow reserve in patients with hypertensive left-ventricular hypertrophy.
Topics: Administration, Sublingual; Adrenergic beta-Antagonists; Aged; Blood Flow Velocity; Blood Pressure; | 2010 |
Impaired endothelium independent vasodilation in nonobstructive hypertrophic cardiomyopathy.
Topics: Administration, Sublingual; Adult; Brachial Artery; Cardiomyopathy, Hypertrophic; Endothelium, Vascu | 2011 |
Design of a randomized, placebo-controlled multicenter trial on the long-term effects of intermittent transdermal nitroglycerin on left ventricular remodeling after acute myocardial infarction. Transdermal Nitroglycerin Investigators Group.
Topics: Administration, Cutaneous; Adult; Aged; Double-Blind Method; Exercise Test; Female; Gated Blood-Pool | 1998 |
Limitation of left ventricular hypertrophy and dysfunction by ACE inhibition after anterior Q-wave myocardial infarction.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Captopril; Chi-Square Distribution; | 1998 |
Effect of NO donors on LV diastolic function in patients with severe pressure-overload hypertrophy.
Topics: Adult; Aged; Aortic Valve Stenosis; Cardiac Catheterization; Coronary Angiography; Coronary Circulat | 1999 |
GISSI-3 study protocol on the effects of lisinopril, of nitrates, and of their association in patients with acute myocardial infarction.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Clinical Protocols; Dipeptides; Drug Combinations; F | 1992 |
15 other studies available for nitroglycerin and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
High prevalence of subclinical cardiovascular abnormalities in patients with systemic lupus erythematosus in spite of a very low clinical damage index.
Topics: Adolescent; Adult; Aortic Valve Insufficiency; Brachial Artery; Cardiovascular Diseases; Carotid Art | 2009 |
Left ventricular hypertrophy is associated with reduced vasodilatory capacity in the brachial artery in patients with longstanding hypertension. A LIFE substudy.
Topics: Acetylcholine; Aged; Arteries; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brachial Arter | 2002 |
Contribution of increased minimal coronary resistance and attenuated vascular adaptive remodeling to myocardial ischemia in patients with systemic hypertension and ventricular hypertrophy.
Topics: Acetylcholine; Aged; Blood Flow Velocity; Cardiac Volume; Coronary Angiography; Coronary Artery Dise | 2004 |
Lack of increased left main coronary artery dimensions in hypertensive patients with left ventricular hypertrophy and coronary artery disease. An intracoronary ultrasound study.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Arteries; Blood Pressur | 2004 |
Images in cardiovascular medicine. Hypertensive brainstem encephalopathy.
Topics: Abdominal Pain; Adult; Blood-Brain Barrier; Brain Edema; Brain Stem; Drugs, Chinese Herbal; Headache | 2007 |
Cardiovascular function in normotensive offspring of persons with essential hypertension and black race.
Topics: Adolescent; Adult; Biomarkers; Black People; Brachial Artery; Carotid Stenosis; Diastole; Echocardio | 2007 |
[Reproducible (latent) obstruction of the left ventricular outflow tract].
Topics: Adult; Aged; Echocardiography; Exercise Test; Female; Humans; Hypertrophy, Left Ventricular; Male; M | 1995 |
Reduced epicardial coronary vasodilator capacity in patients with left ventricular hypertrophy.
Topics: Adult; Coronary Angiography; Coronary Vessels; Dilatation, Pathologic; Humans; Hypertrophy, Left Ven | 1995 |
Dynamic intracavity gradients: a 'new' hemodynamic abnormality in the spectrum of secondary left ventricular hypertrophy.
Topics: Administration, Sublingual; Aged; Aged, 80 and over; Cardiomyopathy, Hypertrophic; Cohort Studies; E | 1994 |
Effect of prolonged nitrate therapy on left ventricular remodeling after canine acute myocardial infarction.
Topics: Animals; Dogs; Echocardiography; Female; Hypertrophy, Left Ventricular; Isosorbide Dinitrate; Male; | 1994 |
Nitroglycerin enhances the ability of dobutamine stress echocardiography to detect hibernating myocardium.
Topics: Animals; Confounding Factors, Epidemiologic; Diagnosis, Differential; Dobutamine; Drug Synergism; Ec | 1997 |
Selective large coronary endothelial dysfunction in conscious dogs with chronic coronary pressure overload.
Topics: Acetylcholine; Animals; Blood Flow Velocity; Blood Pressure; Constriction; Coronary Vessels; Dogs; E | 1998 |
Effect of NO on transmural distribution of blood flow in hypertrophied left ventricle during exercise.
Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Enzyme Inhibitors; Heart Rate; Hemodynamics; Hy | 1999 |
The cardiac endothelin system in established pressure overload left ventricular hypertrophy.
Topics: Amiloride; Animals; Aortic Diseases; Aspartic Acid Endopeptidases; Blood Pressure; Endothelin-1; End | 1999 |
Vasodilatory capacity and vascular structure in long-standing hypertension: a LIFE substudy. Losartan Intervention For Endpoint-Reduction in Hypertension.
Topics: Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brachial Artery; Carotid Artery, Common | 2002 |