Page last updated: 2024-11-01

nitroglycerin and Kidney Failure, Chronic

nitroglycerin has been researched along with Kidney Failure, Chronic in 28 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
"A retrospective cohort study of patients hospitalized with acute congestive heart failure who received intravenous nesiritide or nitroglycerin for ≥6 hours."7.78Comparative effects of nesiritide and nitroglycerin on renal function, and incidence of renal injury by traditional and RIFLE criteria in acute heart failure. ( Ackerbauer, KA; Elkayam, U; Hshieh, S; Hyderi, AF; Ng, TM, 2012)
"A retrospective cohort study of patients hospitalized with acute congestive heart failure who received intravenous nesiritide or nitroglycerin for ≥6 hours."3.78Comparative effects of nesiritide and nitroglycerin on renal function, and incidence of renal injury by traditional and RIFLE criteria in acute heart failure. ( Ackerbauer, KA; Elkayam, U; Hshieh, S; Hyderi, AF; Ng, TM, 2012)
" High-resolution B-mode ultrasonography with automated off-line analysis was used to measure the intima-medial thickness in the common carotid artery and to measure the lumen diameter of the brachial artery at rest, during reactive hyperemia, and after sublingual nitroglycerine."3.71Does renal failure cause an atherosclerotic milieu in patients with end-stage renal disease? ( Case, C; Fathi, R; Isbel, N; Johnson, D; Kennedy, R; Marwick, TH, 2001)
" L-arginine has been used to improve endothelial function by increasing nitric oxide (NO) bioavailability and in animal models this in turn has attenuated the progression of atherosclerosis."2.70Oral L-arginine does not improve endothelial dysfunction in children with chronic renal failure. ( Bennett-Richards, KJ; Bruckdorfer, KR; Deanfield, JE; Donald, AE; Kattenhorn, M; Oakley, GR; Rees, L; Varghese, Z, 2002)
"In ND and HD, reactive hyperemia as well as %NTG and %FMD were attenuated to a similar degree."2.70Impairment of vascular responses to reactive hyperemia and nitric oxide in chronic renal failure. ( Hiraoka, K; Inoue, T; Ishigami, Y; Izumi, M; Nakanishi, T; Otaki, Y; Takamitsu, Y, 2002)
"Amrinone has potent inodilator effects because of its dual mechanism of action."2.68[Hemodynamic effects of amrinone combined with dopamine in patients undergoing living renal transplantation]. ( Hagihira, S; Inagaki, Y; Mashimo, T; Mori, T; Okuno, Y; Takashina, M; Yoshiya, I, 1997)
"The insulin resistance was estimated by the insulin sensitivity index (ISI)."1.37Kidney transplantation improves arterial function measured by pulse wave analysis and endothelium-independent dilatation in uraemic patients despite deterioration of glucose metabolism. ( Clausen, P; Feldt-Rasmussen, B; Hansen, JM; Hornum, M; Idorn, T; Mathiesen, ER, 2011)
"Patients with DM and ESRD had impaired coronary vasodilation to NTG compared to age-matched controls (17."1.35Noninvasive assessment of coronary vasodilation using cardiovascular magnetic resonance in patients at high risk for coronary artery disease. ( Engvall, J; McConnell, MV; Meyer, C; Nguyen, PK; Yang, P, 2008)
"The atherosclerosis is associated with increased arterial stiffness, endothelial dysfunction and elevated oxidative stress and inflammation."1.35Comparison of markers of oxidative stress, inflammation and arterial stiffness between incident hemodialysis and peritoneal dialysis patients--an observational study. ( Coombes, JS; Driver, R; Fassett, RG; Geraghty, DP; Healy, H; Ranganathan, D; Ratanjee, S; Robertson, IK; Sharman, JE, 2009)
"Compared to control subjects, ESRD patients have mechanical artery dysfunction with lower CSC and CSD (0."1.31[Cardiovascular impact of end-stage renal insufficiency in children undergoing hemodialysis]. ( Aggoun, Y; Bonnet, D; Kachaner, J; Laffont, A; Niaudet, P; Sidi, D, 2000)
" After one dosage with a directly acting venodilator (nitroglycerin 5 mg s."1.28Compliance and reactivity of the peripheral venous system in chronic intermittent hemodialysis. ( Draaijer, P; Gladziwa, U; Kooman, JP; Leunissen, KM; Peltenburg, HG; Struyker-Boudier, HA; van Bortel, LM; van Hooff, JP; Wijnen, JA, 1992)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.57)18.7374
1990's7 (25.00)18.2507
2000's14 (50.00)29.6817
2010's6 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van Ballegooijen, AJ1
Zelnick, L1
Hoofnagle, AN1
Hamburg, NM2
Robinson-Cohen, C1
Roy-Chaudhury, P2
Cheung, AK1
Shiu, YT1
de Boer, IH1
Himmelfarb, J2
Beck, G1
Imrey, PB2
Kusek, JW2
Kestenbaum, B1
Penna, FJ1
Harvey, E1
John, P1
Armstrong, D1
Luginbuehl, I1
Odeh, RI1
Alyami, F1
Koyle, MA1
Lorenzo, AJ1
Dember, LM1
Duess, MA1
Larive, B1
Radeva, M1
Kraiss, LW1
Terry, CM1
Vazquez, MA1
Vongpatanasin, W1
Beck, GJ1
Vita, JA1
Nguyen, PK1
Meyer, C1
Engvall, J1
Yang, P1
McConnell, MV1
Hussein, G1
Bughdady, Y1
Kandil, ME1
Bazaraa, HM1
Taher, H1
Morimoto, S1
Yurugi, T1
Aota, Y1
Sakuma, T1
Jo, F1
Nishikawa, M1
Iwasaka, T1
Maki, K1
Fassett, RG1
Driver, R1
Healy, H1
Ranganathan, D1
Ratanjee, S1
Robertson, IK1
Geraghty, DP1
Sharman, JE1
Coombes, JS1
Hornum, M1
Clausen, P1
Idorn, T1
Hansen, JM1
Mathiesen, ER1
Feldt-Rasmussen, B1
Ng, TM1
Ackerbauer, KA1
Hyderi, AF1
Hshieh, S1
Elkayam, U1
Sheikh-Taha, M1
Zeitoun, A1
Akin, EB1
Topçu, O1
Ozcan, H1
Ersöz, S1
Aytaç, S1
Anadol, E1
Bennett-Richards, KJ1
Kattenhorn, M2
Donald, AE1
Oakley, GR1
Varghese, Z2
Bruckdorfer, KR1
Deanfield, JE2
Rees, L2
Nakanishi, T1
Ishigami, Y1
Otaki, Y1
Izumi, M1
Hiraoka, K1
Inoue, T1
Takamitsu, Y1
Vychytil, A1
Födinger, M1
Pleiner, J1
Müllner, M1
Konner, P1
Skoupy, S1
Röhrer, C1
Wolzt, M1
Sunder-Plassmann, G1
Shlipak, MG1
Massie, BM1
Yee, J1
Schneider, AL1
Wacarda, L1
von Klitzing, E1
Kochen, W1
Hellenbrecht, D1
Kooman, JP2
van Hooff, JP2
Leunissen, KM2
Sacchetti, A1
McCabe, J1
Torres, M1
Harris, RL1
Okuno, Y1
Mashimo, T1
Takashina, M1
Hagihira, S1
Inagaki, Y1
Mori, T1
Yoshiya, I1
Gonsorcík, J1
Szakács, M1
Palko, S1
Mydlík, M1
Miyazaki, H1
Matsuoka, H1
Itabe, H1
Usui, M1
Ueda, S1
Okuda, S1
Imaizumi, T1
Aggoun, Y1
Niaudet, P1
Laffont, A1
Sidi, D1
Kachaner, J1
Bonnet, D1
Kurata, N1
Nakamura, S1
Mizumura, J1
Sumi, M1
Nishimura, Y1
Yamamoto, T1
Yasuhara, H1
Kennedy, R1
Case, C1
Fathi, R1
Johnson, D1
Isbel, N1
Marwick, TH1
Bennett-Richards, K1
Donald, A1
Oakley, G1
Wijnen, JA1
Draaijer, P1
van Bortel, LM1
Gladziwa, U1
Peltenburg, HG1
Struyker-Boudier, HA1
Ross, JJ1
Ren, JF1
Land, W1
Chandrasekaran, K1
Mintz, GS1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Far Infrared Therapy on Arteriovenous Fistulas Maturation, Survival and Stenosis. A Randomized, Controlled Open-labeled Multicenter Study[NCT04011072]187 participants (Anticipated)Interventional2019-10-03Recruiting
The Use of Glyceryl Trinitrate Patches in Arteriovenous Fistulas[NCT01685710]Phase 4200 participants (Actual)Interventional2013-04-30Completed
Effects of Heparin on Early Patency of Arteriovenous Fistula in Angioaccess Surgery of Patients With End-Stage Renal Disease[NCT02493504]Phase 4150 participants (Actual)Interventional2011-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nitroglycerin and Kidney Failure, Chronic

ArticleYear
The venous system and dialysis-associated hypotension.
    Contributions to nephrology, 1994, Volume: 106

    Topics: Blood Volume; Body Fluid Compartments; Doxazosin; Humans; Hypertension, Renal; Hypotension; Kidney F

1994

Trials

7 trials available for nitroglycerin and Kidney Failure, Chronic

ArticleYear
Doppler assessment of brachial artery flow as a measure of endothelial dysfunction in pediatric chronic renal failure.
    Pediatric nephrology (Berlin, Germany), 2008, Volume: 23, Issue:11

    Topics: Adolescent; Atherosclerosis; Brachial Artery; Calcium; Child; Endothelium, Vascular; Female; Humans;

2008
Hemodynamic effect of transdermal glyceryl trinitrate on newly constructed arteriovenous fistula.
    World journal of surgery, 2002, Volume: 26, Issue:10

    Topics: Administration, Cutaneous; Arteriovenous Shunt, Surgical; Female; Hemodynamics; Humans; Kidney Failu

2002
Hemodynamic effect of transdermal glyceryl trinitrate on newly constructed arteriovenous fistula.
    World journal of surgery, 2002, Volume: 26, Issue:10

    Topics: Administration, Cutaneous; Arteriovenous Shunt, Surgical; Female; Hemodynamics; Humans; Kidney Failu

2002
Hemodynamic effect of transdermal glyceryl trinitrate on newly constructed arteriovenous fistula.
    World journal of surgery, 2002, Volume: 26, Issue:10

    Topics: Administration, Cutaneous; Arteriovenous Shunt, Surgical; Female; Hemodynamics; Humans; Kidney Failu

2002
Hemodynamic effect of transdermal glyceryl trinitrate on newly constructed arteriovenous fistula.
    World journal of surgery, 2002, Volume: 26, Issue:10

    Topics: Administration, Cutaneous; Arteriovenous Shunt, Surgical; Female; Hemodynamics; Humans; Kidney Failu

2002
Oral L-arginine does not improve endothelial dysfunction in children with chronic renal failure.
    Kidney international, 2002, Volume: 62, Issue:4

    Topics: Administration, Oral; Adolescent; Arginine; Arteriosclerosis; Child; Cross-Over Studies; Dietary Sup

2002
Impairment of vascular responses to reactive hyperemia and nitric oxide in chronic renal failure.
    Nephron, 2002, Volume: 92, Issue:3

    Topics: Blood Pressure; Creatinine; Cysteine; Endothelium, Vascular; Female; Glutathione; Homocysteine; Huma

2002
Acute effect of amino acid peritoneal dialysis solution on vascular function.
    The American journal of clinical nutrition, 2003, Volume: 78, Issue:5

    Topics: Adult; Amino Acids; Blood Flow Velocity; Blood Pressure; Cross-Over Studies; Endothelium, Vascular;

2003
[Hemodynamic effects of amrinone combined with dopamine in patients undergoing living renal transplantation].
    Masui. The Japanese journal of anesthesiology, 1997, Volume: 46, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Amrinone; Cyclic Nucleotide Phosphodiesterases, Type 3;

1997
Does oral folic acid lower total homocysteine levels and improve endothelial function in children with chronic renal failure?
    Circulation, 2002, Apr-16, Volume: 105, Issue:15

    Topics: Administration, Oral; Adolescent; Child; Cross-Over Studies; Dietary Supplements; Double-Blind Metho

2002

Other Studies

20 other studies available for nitroglycerin and Kidney Failure, Chronic

ArticleYear
Association of Vitamin D Metabolites With Arterial Function in the Hemodialysis Fistula Maturation Study.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 69, Issue:6

    Topics: 25-Hydroxyvitamin D 2; Adult; Aged; Anastomosis, Surgical; Arteries; Brachial Artery; Calcifediol; C

2017
Intra-arterial nitroglycerin for intra-operative arterial vasospasm during pediatric renal transplantation.
    Pediatric transplantation, 2016, Volume: 20, Issue:3

    Topics: Allografts; Child, Preschool; Coronary Vasospasm; Female; Hemodynamics; Humans; Injections, Intra-Ar

2016
Vascular Function at Baseline in the Hemodialysis Fistula Maturation Study.
    Journal of the American Heart Association, 2016, 07-22, Volume: 5, Issue:7

    Topics: Adult; Aged; Anastomosis, Surgical; Brachial Artery; Cohort Studies; Cross-Sectional Studies; Female

2016
Noninvasive assessment of coronary vasodilation using cardiovascular magnetic resonance in patients at high risk for coronary artery disease.
    Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2008, May-30, Volume: 10

    Topics: Blood Pressure; Coronary Artery Disease; Coronary Vessels; Diabetes Mellitus; Female; Heart Rate; Hu

2008
Prognostic significance of ankle-brachial index, brachial-ankle pulse wave velocity, flow-mediated dilation, and nitroglycerin-mediated dilation in end-stage renal disease.
    American journal of nephrology, 2009, Volume: 30, Issue:1

    Topics: Aged; Ankle; Ankle Brachial Index; Cohort Studies; Endothelium; Female; Follow-Up Studies; Humans; K

2009
Comparison of markers of oxidative stress, inflammation and arterial stiffness between incident hemodialysis and peritoneal dialysis patients--an observational study.
    BMC nephrology, 2009, Mar-12, Volume: 10

    Topics: Atherosclerosis; Brachial Artery; C-Reactive Protein; Carotid Arteries; Clinical Trials as Topic; Ec

2009
Kidney transplantation improves arterial function measured by pulse wave analysis and endothelium-independent dilatation in uraemic patients despite deterioration of glucose metabolism.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:7

    Topics: Adult; Arteries; Blood Flow Velocity; Blood Pressure; Case-Control Studies; Dilatation; Endothelium,

2011
Comparative effects of nesiritide and nitroglycerin on renal function, and incidence of renal injury by traditional and RIFLE criteria in acute heart failure.
    Journal of cardiovascular pharmacology and therapeutics, 2012, Volume: 17, Issue:1

    Topics: Acute Disease; Acute Kidney Injury; Adult; Aged; Cohort Studies; Female; Heart Failure; Humans; Inci

2012
Effect of intermittent nesiritide administration on kidney function.
    Journal of cardiovascular pharmacology and therapeutics, 2012, Volume: 17, Issue:2

    Topics: Acute Kidney Injury; Female; Heart Failure; Humans; Kidney Failure, Chronic; Male; Natriuretic Pepti

2012
The clinical challenge of cardiorenal syndrome.
    Circulation, 2004, Sep-21, Volume: 110, Issue:12

    Topics: Angiotensin-Converting Enzyme Inhibitors; Case Management; Cohort Studies; Creatinine; Disease Progr

2004
Chronic kidney disease--a disease domain complex.
    Geriatrics, 2008, Volume: 63, Issue:3

    Topics: Aged; Alendronate; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Asp

2008
Experimental observations on peritoneal transport in rabbits.
    Kidney international. Supplement, 1983, Volume: 15

    Topics: Animals; Biological Transport; Creatinine; Disease Models, Animal; Dopamine; Fenoterol; Inulin; Isop

1983
ED management of acute congestive heart failure in renal dialysis patients.
    The American journal of emergency medicine, 1993, Volume: 11, Issue:6

    Topics: Acute Disease; Administration, Cutaneous; Administration, Oral; Administration, Sublingual; Captopri

1993
[Pharmacotherapy of silent myocardial ischemia in patients on hemodialysis].
    Vnitrni lekarstvi, 1996, Volume: 42, Issue:12

    Topics: Adrenergic beta-Agonists; Adult; Aged; Calcium Channel Blockers; Female; Humans; Kidney Failure, Chr

1996
Hemodialysis impairs endothelial function via oxidative stress: effects of vitamin E-coated dialyzer.
    Circulation, 2000, Mar-07, Volume: 101, Issue:9

    Topics: Adult; Brachial Artery; Cross-Over Studies; Echocardiography, Doppler; Endothelium, Vascular; Female

2000
[Cardiovascular impact of end-stage renal insufficiency in children undergoing hemodialysis].
    Archives des maladies du coeur et des vaisseaux, 2000, Volume: 93, Issue:8

    Topics: Adult; Blood Pressure; Brachial Artery; Carotid Artery Diseases; Carotid Artery, Common; Case-Contro

2000
Enhancement of nitroglycerin induced blood vessel relaxation in chronic renal failure model rats.
    Research communications in molecular pathology and pharmacology, 1999, Volume: 106, Issue:1-2

    Topics: Adenine; Animals; Aorta; Aryl Hydrocarbon Hydroxylases; Blood Urea Nitrogen; Cyclic GMP; Cytochrome

1999
Does renal failure cause an atherosclerotic milieu in patients with end-stage renal disease?
    The American journal of medicine, 2001, Feb-15, Volume: 110, Issue:3

    Topics: Adult; Aged; Arteriosclerosis; Brachial Artery; Carotid Artery, Common; Case-Control Studies; Cross-

2001
Compliance and reactivity of the peripheral venous system in chronic intermittent hemodialysis.
    Kidney international, 1992, Volume: 41, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Blood Pressure; Compliance; Doxazosin; Female; Humans; Hy

1992
Transthoracic high frequency (7.5 MHz) echocardiographic assessment of coronary vascular reserve and its relation to left ventricular mass.
    Journal of the American College of Cardiology, 1990, Volume: 16, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cardiomyopathy, Dilated; Coronary Circulation; Coronary Vessels; Ech

1990