nitroglycerin has been researched along with Ischemic Attack, Transient in 25 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Controlled hypotension with nitroglycerin has been used n 30 neurosurgical procedures for aneurysms clipping, artero-veinous malformations, cerebral vascularised tumours and in some cases in the course of serial carotido-cerebral angiography." | 7.66 | [Controlled hypotension with nitroglycerin in neurosurgery (author's transl)]. ( Benech, F; Liboni, W; Lo Russo, G; Urciuoli, R, 1980) |
| "Pooled analyses of previous randomised studies have suggested that very early treatment with glyceryl trinitrate (also known as nitroglycerin) improves functional outcome in patients with acute ischaemic stroke or intracerebral haemorrhage, but this finding was not confirmed in a more recent trial (RIGHT-2)." | 5.51 | Prehospital transdermal glyceryl trinitrate in patients with presumed acute stroke (MR ASAP): an ambulance-based, multicentre, randomised, open-label, blinded endpoint, phase 3 trial. ( Berkhemer, OA; Boomars, R; Boomsma, JMF; Caminada, K; de Leeuw, FE; Dippel, DWJ; Emmer, BJ; Esteve Cuevas, LM; Fransen, PSS; Hofmeijer, J; Kerkhoff, H; Kwa, VIH; Lingsma, HF; Lok, T; Majoie, CBLM; Miedema, I; Nederkoorn, PJ; Nieboer, D; O Pruissen, DM; Raaijmakers, TWM; Reinink, H; Roos, YBWEM; Schipper, MH; Schonewille, WJ; Siegers, A; Uniken Venema, SM; van 't Net, A; van den Berg, SA; van der Lugt, A; van der Worp, HB; van Dijk, GW; van Eijkelenburg, RPJ; van Oostenbrugge, RJ; van Vliet, JA; Visser, MC; Zwetsloot, CP, 2022) |
| "Controlled hypotension with nitroglycerin has been used n 30 neurosurgical procedures for aneurysms clipping, artero-veinous malformations, cerebral vascularised tumours and in some cases in the course of serial carotido-cerebral angiography." | 3.66 | [Controlled hypotension with nitroglycerin in neurosurgery (author's transl)]. ( Benech, F; Liboni, W; Lo Russo, G; Urciuoli, R, 1980) |
| "High blood pressure is common in acute stroke and associated with a worse functional outcome." | 2.90 | Baseline characteristics of the 1149 patients recruited into the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) randomized controlled trial. ( Appleton, JP; Bath, PM; Dixon, M; Scutt, P; Sprigg, N; Wardlaw, JM; Woodhouse, LJ, 2019) |
| "The effects of intravenous nitroglycerin (NTG) combined with dopamine on intracranial pressure (ICP) and cerebral arteriovenous oxygen difference (AVDO2) were studied in 11 patients with acute subarachnoid haemorrhage (SAH)." | 1.29 | Effects of intravenous nitroglycerin combined with dopamine on intracranial pressure and cerebral arteriovenous oxygen difference in patients with acute subarachnoid haemorrhage. ( Aoki, H; Boku, E; Goda, K; Imanishi, M; Iwanaga, H; Koshimae, N; Okuchi, K; Sakaki, T; Tokunaga, H, 1995) |
| "Especially in patients with severe subarachnoid hemorrhage classified as CT group 3 or 4, symptomatic vasospasm occurred in 11 patients (30." | 1.28 | [Clinical effect of nitroglycerin (GTN) on prevention of cerebral vasospasm]. ( Goto, T; Ogayama, H; Sasaki, J; Sasanuma, J; Watanabe, K, 1991) |
| "These results suggest that subarachnoid hemorrhage influences both the generation of EDRF and the constriction of affected arteries." | 1.28 | Pharmacological studies on relaxation of spastic primate cerebral arteries in subarachnoid hemorrhage. ( Cook, DA; Findlay, JM; Kanamaru, K; Krueger, CA; Weir, BK, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (48.00) | 18.7374 |
| 1990's | 10 (40.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| van den Berg, SA | 1 |
| Uniken Venema, SM | 1 |
| Reinink, H | 1 |
| Hofmeijer, J | 1 |
| Schonewille, WJ | 1 |
| Miedema, I | 1 |
| Fransen, PSS | 1 |
| O Pruissen, DM | 1 |
| Raaijmakers, TWM | 1 |
| van Dijk, GW | 1 |
| de Leeuw, FE | 1 |
| van Vliet, JA | 1 |
| Kwa, VIH | 1 |
| Kerkhoff, H | 1 |
| van 't Net, A | 1 |
| Boomars, R | 1 |
| Siegers, A | 1 |
| Lok, T | 1 |
| Caminada, K | 1 |
| Esteve Cuevas, LM | 1 |
| Visser, MC | 1 |
| Zwetsloot, CP | 1 |
| Boomsma, JMF | 1 |
| Schipper, MH | 1 |
| van Eijkelenburg, RPJ | 1 |
| Berkhemer, OA | 1 |
| Nieboer, D | 1 |
| Lingsma, HF | 1 |
| Emmer, BJ | 1 |
| van Oostenbrugge, RJ | 1 |
| van der Lugt, A | 1 |
| Roos, YBWEM | 1 |
| Majoie, CBLM | 1 |
| Dippel, DWJ | 1 |
| Nederkoorn, PJ | 1 |
| van der Worp, HB | 1 |
| Bath, PM | 1 |
| Scutt, P | 1 |
| Appleton, JP | 1 |
| Dixon, M | 1 |
| Woodhouse, LJ | 1 |
| Wardlaw, JM | 1 |
| Sprigg, N | 1 |
| Castriota, F | 1 |
| Cremonesi, A | 1 |
| Manetti, R | 1 |
| Liso, A | 1 |
| Oshola, K | 1 |
| Ricci, E | 1 |
| Balestra, G | 1 |
| RONNOV-JESSEN, V | 2 |
| DATLOW, DW | 1 |
| MASSUMI, RA | 1 |
| Artru, F | 1 |
| Philippon, B | 1 |
| Poussel, JF | 1 |
| Montarry, M | 1 |
| Deleuze, R | 1 |
| Urciuoli, R | 1 |
| Benech, F | 1 |
| Liboni, W | 1 |
| Lo Russo, G | 1 |
| Purvin, VA | 1 |
| Dunn, DW | 1 |
| Sutter, B | 1 |
| Suzuki, S | 1 |
| Arthur, AS | 1 |
| Kassell, NF | 1 |
| Lee, KS | 1 |
| Kurihara, J | 1 |
| Ochiai, N | 1 |
| Kato, H | 1 |
| Tasker, RC | 1 |
| Sahota, SK | 1 |
| Williams, SR | 1 |
| Kaito, N | 1 |
| Onoue, H | 1 |
| Abe, T | 1 |
| Iwanaga, H | 2 |
| Okuchi, K | 1 |
| Koshimae, N | 1 |
| Goda, K | 1 |
| Imanishi, M | 1 |
| Tokunaga, H | 1 |
| Aoki, H | 1 |
| Boku, E | 1 |
| Sakaki, T | 1 |
| Nakao, K | 1 |
| Murata, H | 1 |
| Kanamaru, K | 2 |
| Waga, S | 1 |
| Mitchell, GK | 1 |
| Kistler, JP | 1 |
| Lees, RS | 1 |
| Candia, G | 1 |
| Zervas, NT | 1 |
| Crowell, RM | 1 |
| Ojemann, RG | 1 |
| Abe, K | 1 |
| Yoshiya, I | 1 |
| Kawakami, M | 1 |
| Kodama, N | 1 |
| Toda, N | 1 |
| Sasanuma, J | 1 |
| Goto, T | 1 |
| Ogayama, H | 1 |
| Sasaki, J | 1 |
| Watanabe, K | 1 |
| Weir, BK | 1 |
| Findlay, JM | 1 |
| Krueger, CA | 1 |
| Cook, DA | 1 |
| Pisacreta, M | 1 |
| Jausseran, JM | 1 |
| Richard, D | 1 |
| Reggi, M | 1 |
| Bergeron, P | 1 |
| Courbier, R | 1 |
| Archie, JP | 1 |
| Poletti, CE | 1 |
| Wepsic, JG | 1 |
| Sweet, WH | 1 |
| Tomasi, A | 1 |
| Baratta, PF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cerebral Aneurysms: a Retrospective Study on the Experience in Our Hospital With a Comparative Analysis Between the Different Techniques Used in Its Treatment[NCT04792944] | 247 participants (Actual) | Observational | 2007-01-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for nitroglycerin and Ischemic Attack, Transient
| Article | Year |
|---|---|
Prehospital transdermal glyceryl trinitrate in patients with presumed acute stroke (MR ASAP): an ambulance-based, multicentre, randomised, open-label, blinded endpoint, phase 3 trial.
Topics: Adolescent; Adult; Ambulances; Brain Ischemia; Cerebral Hemorrhage; Humans; Ischemic Attack, Transie | 2022 |
Baseline characteristics of the 1149 patients recruited into the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) randomized controlled trial.
Topics: Aged; Aged, 80 and over; Cohort Studies; Female; Humans; Hypertension; Ischemic Attack, Transient; M | 2019 |
Carbon dioxide reactivity and local cerebral blood flow during prostaglandin E1- or nitroglycerin-induced hypotension.
Topics: Adult; Aged; Alprostadil; Anesthesia, Inhalation; Blood Pressure; Carbon Dioxide; Cerebrovascular Ci | 1992 |
22 other studies available for nitroglycerin and Ischemic Attack, Transient
| Article | Year |
|---|---|
Impact of cerebral protection devices on early outcome of carotid stenting.
Topics: Aged; Blood Vessel Prosthesis Implantation; Carotid Artery, Common; Carotid Stenosis; Cerebrovascula | 2002 |
[Cerebral complications caused by nitroglycerin treatment of angina pectoris].
Topics: Angina Pectoris; Brain Ischemia; Cerebral Infarction; Humans; Ischemic Attack, Transient; Nitroglyce | 1963 |
CEREBRAL COMPLICATIONS IN NITROGLYCERINE TREATMENT OF ANGINA PECTORIS.
Topics: Angina Pectoris; Brain Ischemia; Cerebral Infarction; Humans; Hypotension; Hypotension, Orthostatic; | 1963 |
THE POTENTIAL CEREBRAL AND CARDIOVASCULAR DANGERS OF NITROGLYCERIN.
Topics: Brain Ischemia; Cerebral Infarction; Drug Therapy; Geriatrics; Hypotension; Hypotension, Orthostatic | 1965 |
[Effects of intravenous nitroglycerin on blood pressure, intracranial pressure and total and regional cerebral blood flow in cases of subarachnoid hemorrhage with vasospasm].
Topics: Blood Pressure; Cerebrovascular Circulation; Humans; Intracranial Aneurysm; Intracranial Pressure; I | 1984 |
[Controlled hypotension with nitroglycerin in neurosurgery (author's transl)].
Topics: Adult; Humans; Hypotension; Intracranial Pressure; Intraoperative Complications; Ischemic Attack, Tr | 1980 |
Nitrate-induced transient ischemic attacks.
Topics: Humans; Ischemic Attack, Transient; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin | 1981 |
Effects of subarachnoid hemorrhage on vascular responses to calcitonin gene-related peptide and its related second messengers.
Topics: Analysis of Variance; Animals; Basilar Artery; Calcitonin Gene-Related Peptide; Colforsin; Cyclic AM | 1995 |
Protection by nicorandil against the dysfunction of the central vagal baroreflex system following transient global cerebral ischaemia in dogs.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cerebrovascular Circulation; Dogs; Female; Heart Rate; Isc | 1993 |
Bioenergetic recovery following ischemia in brain slices studied by 31P-NMR spectroscopy: differential age effect of depolarization mediated by endogenous nitric oxide.
Topics: Adenosine Triphosphate; Aging; Analysis of Variance; Animals; Cerebral Cortex; Chromatography, High | 1996 |
Suppression of cerebral vasodilation with endothelin-1.
Topics: Acetylcholine; Animals; Cerebral Arteries; Cerebrovascular Circulation; Dogs; Endothelins; Endotheli | 1995 |
Effects of intravenous nitroglycerin combined with dopamine on intracranial pressure and cerebral arteriovenous oxygen difference in patients with acute subarachnoid haemorrhage.
Topics: Adult; Aged; Brain; Dopamine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; H | 1995 |
Effects of nitroglycerin on vasospasm and cyclic nucleotides in a primate model of subarachnoid hemorrhage.
Topics: Animals; Blood Pressure; Cerebral Angiography; Cerebral Arteries; Cerebral Cortex; Cerebrovascular C | 1996 |
Nitroglycerine by inhaler as treatment for migraine causing cerebral ischaemia.
Topics: Administration, Inhalation; Adult; Female; Humans; Ischemic Attack, Transient; Migraine with Aura; N | 1999 |
Nitroglycerin for neurosurgery.
Topics: Animals; Dogs; Humans; Ischemic Attack, Transient; Nitroglycerin | 1978 |
Suppression of the cerebral vasospastic actions of oxyhemoglobin by ascorbic acid.
Topics: Animals; Ascorbic Acid; Aspirin; Basilar Artery; Cattle; Cerebral Arteries; Dogs; Female; Ischemic A | 1991 |
[Clinical effect of nitroglycerin (GTN) on prevention of cerebral vasospasm].
Topics: Adult; Aged; Aged, 80 and over; Drug Evaluation; Female; Humans; Intracranial Aneurysm; Ischemic Att | 1991 |
Pharmacological studies on relaxation of spastic primate cerebral arteries in subarachnoid hemorrhage.
Topics: Acetylcholine; Animals; Calcimycin; Cerebral Angiography; Cerebral Arteries; Endothelium, Vascular; | 1989 |
[Carotid surgery associated with coronary pathology: diagnostic screening and surgical timing].
Topics: Aged; Aged, 80 and over; Carotid Arteries; Coronary Disease; Endarterectomy; Female; Humans; Ischemi | 1987 |
The relationship of early hypertension following carotid endarterectomy to intraoperative cerebral ischemia.
Topics: Aged; Arterial Occlusive Diseases; Blood Vessel Prosthesis; Brain Ischemia; Carotid Artery Diseases; | 1988 |
Middle cerebral arterial spasm from subarachnoid blood: spasmolysis with topical use of nitroglycerin.
Topics: Animals; Cerebral Arterial Diseases; Dogs; Ischemic Attack, Transient; Nitroglycerin; Subarachnoid H | 1972 |
[Idiopathic orthostatic hypotension].
Topics: Angiotensin II; Electroencephalography; Electromyography; Humans; Hypotension, Orthostatic; Ischemic | 1968 |