nitroglycerin has been researched along with Intraocular Pressure in 24 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two separate studies of the effects of nitroglycerin (NTG) on intraocular pressure (IOP) were conducted." | 9.06 | Intranasal nitroglycerin and intraocular pressure during general anesthesia. ( Grover, VK; Mahajan, RP; Sharma, SL; Singh, H, 1988) |
| "Two separate studies of the effects of nitroglycerin (NTG) on intraocular pressure (IOP) were conducted." | 5.06 | Intranasal nitroglycerin and intraocular pressure during general anesthesia. ( Grover, VK; Mahajan, RP; Sharma, SL; Singh, H, 1988) |
| "25% nipradilol solution lowered intraocular pressure (IOP) with relatively weak contralateral effects in a dose-dependent manner with a maximum reduction of 6 mm Hg and an effect duration of 6 hours." | 3.70 | Effects of topical nipradilol, a beta-blocking agent with alpha-blocking and nitroglycerin-like activities, on aqueous humor dynamics and fundus circulation. ( Araie, M; Kanno, M; Sawanobori, K; Tomita, K, 1998) |
| " The effects of nitroglycerin on the eye and specifically on intraocular pressure has been investigated with diverse results." | 3.70 | Nitrate therapy may retard glaucomatous optic neuropathy, perhaps through modulation of glutamate receptors. ( Chaturvedi, N; Dreyer, EB; Gorla, M; Grosskreutz, CL; Kanellopoulos, AJ; Lipton, SA; Vorwerk, CK; Zurakowski, D, 1998) |
| "The nitrovasodilators nitroglycerin (NTG) and hydralazine (HZN) were investigated for their effects on intraocular pressure (IOP) and outflow facility in the cynomolgus monkey eye in vivo." | 3.69 | Nitrovasodilator effects on intraocular pressure and outflow facility in monkeys. ( Erickson, K; Nathanson, JA; Schuman, JS, 1994) |
| " Nitroglycerin lowered intraocular pressure in all patients when administered by the perfusion technique." | 3.66 | Organic nitrate therapy in glaucoma. ( Wizemann, AJ; Wizemann, V, 1980) |
| "Intravenously administered nitroglycerin lowers intraocular pressure both in glaucoma patients and healthy subjects." | 3.66 | [The use of organic nitrates to lower intraocular pressure in outpatient and surgical treatment (author's transl)]. ( Wizemann, A; Wizemann, V, 1980) |
| "Twenty patients with type 1 diabetes mellitus featuring no or mild nonproliferative diabetic retinopathy and 20 healthy, age-matched subjects were included in this study." | 2.74 | Reduced retinal vessel response to flicker stimulation but not to exogenous nitric oxide in type 1 diabetes. ( Garhofer, G; Karl, K; Pemp, B; Resch, H; Schmetterer, L; Weigert, G; Wolzt, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (54.17) | 18.7374 |
| 1990's | 5 (20.83) | 18.2507 |
| 2000's | 2 (8.33) | 29.6817 |
| 2010's | 3 (12.50) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Acharya, S | 1 |
| Rogers, P | 1 |
| Krishnamoorthy, RR | 1 |
| Stankowska, DL | 1 |
| Dias, HV | 1 |
| Yorio, T | 1 |
| Wilcox, PA | 1 |
| Strong, TD | 1 |
| Sebbag, L | 1 |
| Allbaugh, RA | 1 |
| Pournaras, JA | 1 |
| Nguyen, C | 1 |
| Mameletzi, E | 1 |
| Zografos, L | 1 |
| Wolfensberger, TJ | 1 |
| Pemp, B | 1 |
| Garhofer, G | 1 |
| Weigert, G | 1 |
| Karl, K | 1 |
| Resch, H | 1 |
| Wolzt, M | 1 |
| Schmetterer, L | 1 |
| Shen, SC | 1 |
| Ho, WJ | 2 |
| Wu, SC | 2 |
| Yu, KH | 1 |
| Lin, HC | 1 |
| Lin, YS | 1 |
| Tsay, PK | 2 |
| Chu, PH | 1 |
| Su, WW | 1 |
| Cheng, ST | 1 |
| Chang, SH | 1 |
| Masuda, A | 1 |
| Miyazaki, H | 1 |
| Yahagi, N | 1 |
| Yamazaki, M | 1 |
| Ito, Y | 1 |
| Wizemann, AJ | 1 |
| Wizemann, V | 2 |
| Wizemann, A | 1 |
| de Laage, P | 1 |
| Achard, P | 1 |
| Maestracci, P | 1 |
| Wang, RF | 1 |
| Podos, SM | 1 |
| Schuman, JS | 1 |
| Erickson, K | 1 |
| Nathanson, JA | 3 |
| Kanno, M | 1 |
| Araie, M | 1 |
| Tomita, K | 1 |
| Sawanobori, K | 1 |
| Zurakowski, D | 1 |
| Vorwerk, CK | 1 |
| Gorla, M | 1 |
| Kanellopoulos, AJ | 1 |
| Chaturvedi, N | 1 |
| Grosskreutz, CL | 1 |
| Lipton, SA | 1 |
| Dreyer, EB | 1 |
| Saman, K | 1 |
| Hradecká, V | 1 |
| Brodehl, D | 1 |
| Steinbach, PD | 1 |
| Jantzen, JP | 1 |
| Hennes, HJ | 1 |
| Wallenfang, T | 1 |
| Vrba, K | 1 |
| Svejda, J | 1 |
| Debowska-Weissowa, J | 1 |
| Malukiewicz-Wiśniewska, G | 1 |
| Karwowski, J | 1 |
| Mahajan, RP | 1 |
| Grover, VK | 1 |
| Sharma, SL | 1 |
| Singh, H | 1 |
| Leydhecker, W | 1 |
| Waller, W | 1 |
| Krieglstein, G | 1 |
| Robertson, DM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Correlation of Flicker Induced and Flow Mediated Vasodilatation in Patients With Endothelial Dysfunction and Healthy Volunteers[NCT00432029] | 80 participants (Actual) | Interventional | 2006-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nitroglycerin and Intraocular Pressure
| Article | Year |
|---|---|
The eye and adverse drug effects. Some selected considerations.
Topics: Acetazolamide; Amyl Nitrite; Anesthesia; Chloramphenicol; Chloroquine; Contraceptives, Oral; Dexamet | 1972 |
3 trials available for nitroglycerin and Intraocular Pressure
| Article | Year |
|---|---|
Effect of topical nitric oxide donors 0.03% nitroglycerin and 0.1% hydralazine on intraocular pressure in healthy canine eyes.
Topics: Animals; Dogs; Hydralazine; Intraocular Pressure; Nitric Oxide Donors; Nitroglycerin; Tonometry, Ocu | 2022 |
Reduced retinal vessel response to flicker stimulation but not to exogenous nitric oxide in type 1 diabetes.
Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Glyca | 2009 |
Intranasal nitroglycerin and intraocular pressure during general anesthesia.
Topics: Administration, Intranasal; Adult; Anesthesia, General; Blood Pressure; Double-Blind Method; Heart R | 1988 |
20 other studies available for nitroglycerin and Intraocular Pressure
| Article | Year |
|---|---|
Design and synthesis of novel hybrid sydnonimine and prodrug useful for glaucomatous optic neuropathy.
Topics: Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Glaucoma; Humans; Hydrogen | 2016 |
Successful treatment of longstanding vasospastic central retinal artery occlusion.
Topics: Acetazolamide; Aged; Antihypertensive Agents; Blindness; Diuretics; Drug Therapy, Combination; Femal | 2010 |
Peripheral vascular endothelial dysfunction in glaucomatocyclitic crisis: a preliminary study.
Topics: Adolescent; Adult; Autoantibodies; Blood Flow Velocity; Blood Glucose; Blood Pressure; Brachial Arte | 2010 |
Glaucoma is associated with peripheral vascular endothelial dysfunction.
Topics: Blood Flow Velocity; Blood Pressure; Body Constitution; Brachial Artery; C-Reactive Protein; Case-Co | 2008 |
[Effect of hypotension induced by trimethaphan and nitroglycerin on intraocular pressure in man].
Topics: Adult; Anesthesia, General; Humans; Hypotension, Controlled; Intraocular Pressure; Middle Aged; Nitr | 1983 |
Organic nitrate therapy in glaucoma.
Topics: Administration, Oral; Dose-Response Relationship, Drug; Glaucoma; Humans; Infusions, Parenteral; Int | 1980 |
[The use of organic nitrates to lower intraocular pressure in outpatient and surgical treatment (author's transl)].
Topics: Dose-Response Relationship, Drug; Glaucoma; Humans; Intraocular Pressure; Isosorbide Dinitrate; Nitr | 1980 |
[The prevention of expulsive hemorrhage with trinitroglycerine].
Topics: Humans; Intraocular Pressure; Nitroglycerin; Postoperative Complications; Retinal Hemorrhage; Vasodi | 1982 |
Effect of the topical application of nitroglycerin on intraocular pressure in normal and glaucomatous monkeys.
Topics: Animals; Female; Glaucoma; Intraocular Pressure; Macaca fascicularis; Nitroglycerin | 1995 |
Nitrovasodilator effects on intraocular pressure and outflow facility in monkeys.
Topics: Animals; Aqueous Humor; Depression, Chemical; Dose-Response Relationship, Drug; Female; Hydralazine; | 1994 |
Effects of topical nipradilol, a beta-blocking agent with alpha-blocking and nitroglycerin-like activities, on aqueous humor dynamics and fundus circulation.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aqueous | 1998 |
Nitrate therapy may retard glaucomatous optic neuropathy, perhaps through modulation of glutamate receptors.
Topics: Aged; Aged, 80 and over; Comorbidity; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ma | 1998 |
[Nitroglycerin and glaucoma].
Topics: Aged; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Nitroglycerin | 1975 |
[What is the effect of glyceryl trinitrate on the intraocular pressure? (author's transl)].
Topics: Administration, Oral; Animals; Blood Pressure; Glaucoma; Humans; Injections, Intravenous; Intraocula | 1975 |
Nitrovasodilators as a new class of ocular hypotensive agents.
Topics: Administration, Topical; Animals; Aqueous Humor; Atrial Natriuretic Factor; Blood Pressure; Dose-Res | 1992 |
Nitroglycerine, succinylcholine and intraocular pressure.
Topics: Animals; Hemodynamics; Intraocular Pressure; Nitroglycerin; Succinylcholine; Swine | 1989 |
Direct application of a guanylate cyclase activator lowers intraocular pressure.
Topics: Animals; Blood Pressure; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Intraocular Pres | 1988 |
[Is nitroglycerin contraindicated in glaucoma?].
Topics: Aged; Angina Pectoris; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Nitroglycerin | 1986 |
[Effect of nitroglycerin on intraocular pressure].
Topics: Adult; Aged; Coronary Disease; Humans; Intraocular Pressure; Middle Aged; Nitroglycerin | 1986 |
[The effect of vasodilators on the intraocular pressure (author's transl)].
Topics: Administration, Intranasal; Administration, Oral; Benzyl Compounds; Blood Pressure; Cycloheptanes; D | 1974 |