Page last updated: 2024-11-01

nitroglycerin and Intermittent Claudication

nitroglycerin has been researched along with Intermittent Claudication in 9 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Intermittent Claudication: A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's3 (33.33)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Lawall, H1
Bramlage, P1
Gorath, M1
Wittig, T1
Goldberg, LR1
Stouffer, GA1
Ray, SA1
Buckenham, TM1
Belli, AM1
Taylor, RS1
Dormandy, JA1
Walker, SR1
Tennant, S1
MacSweeney, ST1
Heer, R1
Walker, S1
MacSweeney, S1
Váradi, A1
Solti, F1
Iskum, M1
Vaccaro, E1
Solitro, A1
Barba, C1
Eliakim, M1
Sapoznikov, D1
Keynan, A1
Weinman, J1
Kühn, P1
Kohn, P1

Trials

5 trials available for nitroglycerin and Intermittent Claudication

ArticleYear
Intermittent Administration of Nitroglycerin Sublingual Powder Compared with Placebo in Outpatients with Peripheral Artery Disease: Results of a Randomised Proof of Concept Study.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2021, Volume: 61, Issue:3

    Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Ambulatory Care; Double-Blind Method; Dr

2021
The nature and importance of changes in toe-brachial pressure indices following percutaneous transluminal angioplasty for leg ischaemia.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 1997, Volume: 14, Issue:2

    Topics: Aged; Angioplasty, Balloon; Ankle; Blood Pressure; Brachial Artery; Chronic Disease; Combined Modali

1997
A randomized, double-blind, placebo-controlled, crossover study to assess the immediate effect of sublingual glyceryl trinitrate on the ankle brachial pressure index, claudication, and maximum walking distance of patients with intermittent claudication.
    Journal of vascular surgery, 1998, Volume: 28, Issue:5

    Topics: Administration, Sublingual; Aged; Blood Pressure; Cross-Over Studies; Double-Blind Method; Exercise

1998
The effects of sublingual glyceryl trinitrate on walking distance in patients with intermittent claudication. A randomised, doubled-blind, placebo-controlled, cross-over study.
    Current medical research and opinion, 2001, Volume: 17, Issue:2

    Topics: Administration, Sublingual; Aged; Aged, 80 and over; Cross-Over Studies; Double-Blind Method; Female

2001
[Oxyfedrin in long term therapy of angina pectoris (double blind test with cross over)].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1972, Volume: 53, Issue:3

    Topics: Aged; Amines; Angina Pectoris; Blood Pressure; Diabetes Complications; Electrocardiography; Female;

1972

Other Studies

4 other studies available for nitroglycerin and Intermittent Claudication

ArticleYear
Images in cardiovascular medicine. Iliac artery stress test.
    Circulation, 2004, Apr-13, Volume: 109, Issue:14

    Topics: Aorta, Abdominal; Aortography; Blood Pressure; Constriction, Pathologic; Exercise Test; Femoral Arte

2004
The effect of vasodilator therapy on the limb circulation in hypertension.
    Acta medica Hungarica, 1990, Volume: 47, Issue:3-4

    Topics: Arterial Occlusive Diseases; Female; Humans; Hydralazine; Hypertension; Intermittent Claudication; L

1990
Levodopa in the treatment of arterial insufficiency of the lower limbs. Clinical and rheographic trial.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:12

    Topics: Administration, Oral; Adult; Aged; Arterial Occlusive Diseases; Arteriosclerosis Obliterans; Dihydro

1973
The effect of long-acting glyceryl trinitrate on peripheral circulation.
    Geriatrics, 1972, Volume: 27, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Arteries; Arteriosclerosis; Blood Circulation; Femora

1972