nitroglycerin has been researched along with Impotence in 45 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Transcutaneous nitroglycerine has previously been reported to be effective in the treatment of erectile dysfunction." | 9.09 | Transcutaneous nitroglycerine in the treatment of erectile dysfunction: a placebo controlled clinical trial. ( Gramkow, J; Lendorf, A; Meyhoff, HH; Zhu, J, 1999) |
| "This study was done to evaluate the effectiveness of transdermal nitroglycerin in the treatment of erectile dysfunction in males with spinal cord lesions as compared to the treatment with intracavernous injection of papaverine." | 9.08 | Comparison of transdermal nitroglycerin and intracavernous injection of papaverine in the treatment of erectile dysfunction in patients with spinal cord lesions. ( Kurien, T; Renganathan, R; Suranjan, B, 1997) |
| " of a 2% solution) was studied under strict laboratory conditions in a double-blind controlled trial on 33 patients (4 with neurogenic plus arterial, 10 with neurogenic and 19 with arterial impotence) and compared to placebo and nitroglycerin (2." | 9.07 | Minoxidil versus nitroglycerin: a prospective double-blind controlled trial in transcutaneous erection facilitation for organic impotence. ( Cavallini, G, 1991) |
| "Topical nitroglycerin ointment has been studied in the laboratory as a possible treatment for impotence of various etiologies." | 7.68 | Nitroglycerin ointment in the treatment of impotence. ( Anderson, DC; Nunez, BD, 1993) |
| "For yohimbine, mean C(max) was 42 +/- 11 (2." | 6.71 | An oral yohimbine/L-arginine combination (NMI 861) for the treatment of male erectile dysfunction: a pharmacokinetic, pharmacodynamic and interaction study with intravenous nitroglycerine in healthy male subjects. ( Hughes, DM; Kernohan, AF; McIntyre, M; Reid, JL; Tam, SW; Worcel, M, 2005) |
| "The nitroglycerin plasters were applied on the skin of the penile shaft and a positive response was obtained in 12 men." | 5.28 | Transcutaneous nitroglycerin in the treatment of erectile dysfunction in spinal cord injured. ( Biering-Sørensen, F; Sønksen, J, 1992) |
| "Nitroglycerin plasters were applied to the penis in 10 impotent men and the erectile effect assessed." | 5.28 | Non-invasive management of impotence with transcutaneous nitroglycerin. ( Bødker, A; Meyhoff, HH; Rosenkilde, P, 1992) |
| "Transcutaneous nitroglycerine has previously been reported to be effective in the treatment of erectile dysfunction." | 5.09 | Transcutaneous nitroglycerine in the treatment of erectile dysfunction: a placebo controlled clinical trial. ( Gramkow, J; Lendorf, A; Meyhoff, HH; Zhu, J, 1999) |
| "This study was done to evaluate the effectiveness of transdermal nitroglycerin in the treatment of erectile dysfunction in males with spinal cord lesions as compared to the treatment with intracavernous injection of papaverine." | 5.08 | Comparison of transdermal nitroglycerin and intracavernous injection of papaverine in the treatment of erectile dysfunction in patients with spinal cord lesions. ( Kurien, T; Renganathan, R; Suranjan, B, 1997) |
| " of a 2% solution) was studied under strict laboratory conditions in a double-blind controlled trial on 33 patients (4 with neurogenic plus arterial, 10 with neurogenic and 19 with arterial impotence) and compared to placebo and nitroglycerin (2." | 5.07 | Minoxidil versus nitroglycerin: a prospective double-blind controlled trial in transcutaneous erection facilitation for organic impotence. ( Cavallini, G, 1991) |
| "Currently, 3 phosphodiesterase 5 (PDE5) inhibitor agents are available worldwide for the treatment of erectile dysfunction (ED): sildenafil, vardenafil, and tadalafil." | 4.82 | Pharmacology and drug interaction effects of the phosphodiesterase 5 inhibitors: focus on alpha-blocker interactions. ( Kloner, RA, 2005) |
| "Despite the proven efficacy of oral therapy for erectile dysfunction (ED), some patients are unable to take these medications because of drug interactions (ie, sildenafil and nitroglycerin) or a lack of response." | 4.81 | Topical agents and erectile dysfunction: is there a place? ( McVary, KT; Yap, RL, 2002) |
| "Sildenafil citrate is the first orally active therapy proved to be effective and safe treatment for erectile dysfunction (ED)." | 4.80 | Cardiovascular effects of sildenafil citrate and recommendations for its use. ( Kloner, RA; Zusman, RM, 1999) |
| "Topical nitroglycerin ointment has been studied in the laboratory as a possible treatment for impotence of various etiologies." | 3.68 | Nitroglycerin ointment in the treatment of impotence. ( Anderson, DC; Nunez, BD, 1993) |
| " The most commonly reported adverse events during MED2005 treatment were headache (patients, n = 18 [7." | 2.87 | Efficacy and Safety of MED2005, a Topical Glyceryl Trinitrate Formulation, in the Treatment of Erectile Dysfunction: A Randomized Crossover Study. ( Eardley, I; Holland, T; Ralph, DJ; Taubel, J; Terrill, P, 2018) |
| "For yohimbine, mean C(max) was 42 +/- 11 (2." | 2.71 | An oral yohimbine/L-arginine combination (NMI 861) for the treatment of male erectile dysfunction: a pharmacokinetic, pharmacodynamic and interaction study with intravenous nitroglycerine in healthy male subjects. ( Hughes, DM; Kernohan, AF; McIntyre, M; Reid, JL; Tam, SW; Worcel, M, 2005) |
| "Erectile dysfunction is a frequent condition in cardiovascular patients." | 2.41 | [Drug treatment of erection disorders in patients with cardiovascular disease]. ( Kingma, JH; Meuleman, EJ, 2001) |
| "Pharmacological treatment of erectile dysfunction includes all therapeutic modalities based on the use of erectogenic drugs, regardless of the route of administration." | 2.39 | Pharmacological management of erectile dysfunction. ( Guazzoni, G; Montorsi, F; Pozza, G; Rigatti, P, 1995) |
| "The nitroglycerin plasters were applied on the skin of the penile shaft and a positive response was obtained in 12 men." | 1.28 | Transcutaneous nitroglycerin in the treatment of erectile dysfunction in spinal cord injured. ( Biering-Sørensen, F; Sønksen, J, 1992) |
| "Nitroglycerin plasters were applied to the penis in 10 impotent men and the erectile effect assessed." | 1.28 | Non-invasive management of impotence with transcutaneous nitroglycerin. ( Bødker, A; Meyhoff, HH; Rosenkilde, P, 1992) |
| "Progress in diagnosis and therapy of impotence is handicapped by the absence of a validated and objective method for evaluating the vascular system; a gold-standard for vasculogenic impotence is needed." | 1.27 | Pharmacoarteriography in the evaluation of impotence. ( Bookstein, JJ; Kessler, W; Parsons, L; Valji, K, 1987) |
| "The prevalence of atherosclerotic impotence is not known but may be relatively high in older men." | 1.26 | Impotence responsive to glyceryl trinitrate. ( Mudd, JW, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (17.78) | 18.7374 |
| 1990's | 23 (51.11) | 18.2507 |
| 2000's | 10 (22.22) | 29.6817 |
| 2010's | 3 (6.67) | 24.3611 |
| 2020's | 1 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, A | 1 |
| Reisman, Y | 1 |
| Ralph, DJ | 1 |
| Eardley, I | 1 |
| Taubel, J | 1 |
| Terrill, P | 1 |
| Holland, T | 1 |
| Seftel, AD | 1 |
| Mamedov, MN | 1 |
| Digigova, RT | 1 |
| Sharvadze, GG | 1 |
| Ugurchieva, ZO | 1 |
| Kovrigina, MN | 1 |
| Stroeva, MV | 1 |
| Hisasue, S | 1 |
| Sato, Y | 1 |
| Tsukamoto, T | 1 |
| Yap, RL | 1 |
| McVary, KT | 1 |
| Khandheria, BK | 1 |
| DeBusk, RF | 1 |
| Abrams, J | 1 |
| Kloner, RA | 3 |
| Kernohan, AF | 1 |
| McIntyre, M | 1 |
| Hughes, DM | 1 |
| Tam, SW | 1 |
| Worcel, M | 1 |
| Reid, JL | 1 |
| Wolf, HI | 1 |
| Lue, TF | 1 |
| Cavallini, G | 2 |
| Anderson, DC | 2 |
| Seifert, CF | 1 |
| Nunez, BD | 1 |
| Porst, H | 1 |
| Montorsi, F | 1 |
| Guazzoni, G | 1 |
| Rigatti, P | 1 |
| Pozza, G | 1 |
| Christ, GJ | 1 |
| Kim, DC | 1 |
| Taub, HC | 1 |
| Gondré, CM | 1 |
| Melman, A | 1 |
| Renganathan, R | 1 |
| Suranjan, B | 1 |
| Kurien, T | 1 |
| Schwartz, I | 1 |
| McCarthy, D | 1 |
| Gramkow, J | 1 |
| Lendorf, A | 1 |
| Zhu, J | 1 |
| Meyhoff, HH | 2 |
| Zusman, RM | 1 |
| Omote, M | 1 |
| Meuleman, EJ | 1 |
| Kingma, JH | 1 |
| Mudd, JW | 1 |
| Green, AW | 1 |
| McGuffey, E | 1 |
| Kramer, L | 1 |
| Biering-Sørensen, F | 2 |
| Sønksen, J | 2 |
| Rosenkilde, P | 1 |
| Bødker, A | 1 |
| Bohndorf, K | 2 |
| Sikora, R | 2 |
| Sohn, M | 2 |
| Adam, G | 1 |
| Günther, RW | 1 |
| Holzki, G | 1 |
| Gall, H | 1 |
| Bähren, W | 1 |
| Scherb, W | 1 |
| Sparwasser, C | 1 |
| Negelev, S | 1 |
| Heaton, JP | 2 |
| Morales, A | 3 |
| Owen, J | 1 |
| Saunders, FW | 1 |
| Fenemore, J | 3 |
| Gehl, HB | 1 |
| Vorwerk, D | 1 |
| Ahmad, S | 1 |
| Owen, JA | 1 |
| Saunders, F | 1 |
| Harris, C | 1 |
| Reid, K | 1 |
| Surridge, D | 1 |
| Condra, M | 1 |
| Claes, H | 1 |
| Baert, L | 1 |
| Bookstein, JJ | 2 |
| Valji, K | 1 |
| Parsons, L | 1 |
| Kessler, W | 1 |
| Lang, EV | 1 |
| Condra, MS | 1 |
| Owen, JE | 1 |
| Surridge, DH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Heart Rate and Blood Pressure Response During Exercise and Sexual Activity in Normotensive and Hypertensive Volunteers[NCT00143988] | 36 participants (Actual) | Observational | 2004-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 reviews available for nitroglycerin and Impotence
| Article | Year |
|---|---|
Development of a novel topical formulation of glyceryl trinitrate for the treatment of erectile dysfunction.
Topics: Endothelial Cells; Erectile Dysfunction; Humans; Male; Nitroglycerin; Penile Erection; Piperazines; | 2020 |
[Detection of erectile dysfunction and peculiarities of its treatment in men with high cardiovascular risk].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atherosclerosis; Cardiovascul | 2010 |
[Adverse events and drug interactions of sildenafil].
Topics: Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Interactions; Erectile Dysfun | 2002 |
Topical agents and erectile dysfunction: is there a place?
Topics: Administration, Topical; Alprostadil; Erectile Dysfunction; Humans; Male; Minoxidil; Nitroglycerin; | 2002 |
Cardiovascular effects of the 3 phosphodiesterase-5 inhibitors approved for the treatment of erectile dysfunction.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adrenergic alpha-Antagonists; Arteriosclerosis; Blood Pressure; | 2004 |
Pharmacology and drug interaction effects of the phosphodiesterase 5 inhibitors: focus on alpha-blocker interactions.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adrenergic alpha-Antagonists; Carbolines; Cyclic Nucleotide Pho | 2005 |
Topical nitrate treatment of impotence.
Topics: Administration, Topical; Clinical Trials as Topic; Erectile Dysfunction; Humans; Male; Nitroglycerin | 1993 |
Pharmacological management of erectile dysfunction.
Topics: Administration, Oral; Erectile Dysfunction; Humans; Injections, Intravenous; Male; Nitroglycerin; Pa | 1995 |
Cardiovascular effects of sildenafil citrate and recommendations for its use.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Administration, Oral; Antihypertensive Agents; Blood Pressure; | 1999 |
[Pharmacological profiles of sildenafil (VIAGRA) in the treatment of erectile dysfunction: efficacy and drug interaction with nitrate].
Topics: Animals; Blood Pressure; Cyclic GMP; Dogs; Drug Interactions; Erectile Dysfunction; Humans; Male; Ni | 1999 |
[Drug treatment of erection disorders in patients with cardiovascular disease].
Topics: Cardiovascular Diseases; Contraindications; Drug Interactions; Erectile Dysfunction; Humans; Isosorb | 2001 |
Sexual activity and the postmyocardial infarction patient.
Topics: Adult; Alkalosis; Attitude; Coitus; Death, Sudden; Electrocardiography; Erectile Dysfunction; Exerci | 1975 |
Penile erection in men with spinal cord or cauda equina lesions.
Topics: Adult; Cauda Equina; Equipment and Supplies; Erectile Dysfunction; Female; Humans; Male; Nitroglycer | 1992 |
9 trials available for nitroglycerin and Impotence
| Article | Year |
|---|---|
Efficacy and Safety of MED2005, a Topical Glyceryl Trinitrate Formulation, in the Treatment of Erectile Dysfunction: A Randomized Crossover Study.
Topics: Adult; Aged; Coitus; Cross-Over Studies; Double-Blind Method; Erectile Dysfunction; Humans; Male; Mi | 2018 |
An oral yohimbine/L-arginine combination (NMI 861) for the treatment of male erectile dysfunction: a pharmacokinetic, pharmacodynamic and interaction study with intravenous nitroglycerine in healthy male subjects.
Topics: Administration, Oral; Adolescent; Adrenergic alpha-Antagonists; Adult; Arginine; Cross-Over Studies; | 2005 |
Minoxidil versus nitroglycerine: a prospective, double-blind, controlled trial in transcutaneous therapy for organic impotence.
Topics: Administration, Cutaneous; Adult; Aged; Double-Blind Method; Erectile Dysfunction; Humans; Male; Mid | 1994 |
Comparison of transdermal nitroglycerin and intracavernous injection of papaverine in the treatment of erectile dysfunction in patients with spinal cord lesions.
Topics: Administration, Cutaneous; Adult; Cross-Over Studies; Erectile Dysfunction; Humans; Injections; Male | 1997 |
Transcutaneous nitroglycerine in the treatment of erectile dysfunction: a placebo controlled clinical trial.
Topics: Administration, Cutaneous; Adult; Aged; Cross-Over Studies; Double-Blind Method; Erectile Dysfunctio | 1999 |
Minoxidil versus nitroglycerin: a prospective double-blind controlled trial in transcutaneous erection facilitation for organic impotence.
Topics: Administration, Topical; Adult; Aged; Double-Blind Method; Erectile Dysfunction; Gels; Humans; Male; | 1991 |
Topical nitroglycerin: a potential treatment for impotence.
Topics: Administration, Topical; Erectile Dysfunction; Humans; Male; Middle Aged; Nitroglycerin; Penile Erec | 1989 |
Transcutaneous nitroglycerin therapy in the treatment of impotence.
Topics: Administration, Cutaneous; Double-Blind Method; Erectile Dysfunction; Humans; Male; Nitroglycerin; P | 1989 |
Oral and transcutaneous pharmacologic agents in the treatment of impotence.
Topics: Administration, Cutaneous; Administration, Oral; Clinical Trials as Topic; Endocrine System Diseases | 1988 |
23 other studies available for nitroglycerin and Impotence
| Article | Year |
|---|---|
Re: Efficacy and Safety of MED2005, a Topical Glyceryl Trinitrate Formulation, in the Treatment of Erectile Dysfunction: A Randomized Crossover Study.
Topics: Administration, Topical; Cross-Over Studies; Double-Blind Method; Erectile Dysfunction; Humans; Male | 2018 |
Erection, erectile dysfunction: what has heart got to do with it?
Topics: Contraindications; Drug Interactions; Erectile Dysfunction; Hemodynamics; Humans; Male; Myocardial I | 2003 |
Sexual activity in patients with angina.
Topics: Angina Pectoris; Emergencies; Erectile Dysfunction; Humans; Male; Nitroglycerin; Phosphodiesterase I | 2003 |
Time course of the interaction between tadalafil and nitrates.
Topics: Angina Pectoris; Carbolines; Drug Interactions; Erectile Dysfunction; Humans; Male; Nitroglycerin; P | 2004 |
[Dionysos plaster or gunpowder without bullets].
Topics: Administration, Cutaneous; Erectile Dysfunction; Humans; Male; Nitroglycerin; Penile Erection; Penis | 2008 |
Organic impotence.
Topics: Diagnosis, Differential; Erectile Dysfunction; Humans; Hyperprolactinemia; Impotence, Vasculogenic; | 1994 |
Nitroglycerin ointment in the treatment of impotence.
Topics: Administration, Cutaneous; Arteriosclerosis; Erectile Dysfunction; Humans; Male; Middle Aged; Nitrog | 1993 |
[Nitroglycerin ointment in erectile impotence?].
Topics: Adult; Erectile Dysfunction; Humans; Male; Nitroglycerin; Ointments; Penile Erection | 1993 |
Characterization of nitroglycerine-induced relaxation in human corpus cavernosum smooth muscle: implications to erectile physiology and dysfunction.
Topics: Adult; Aged; Aged, 80 and over; Erectile Dysfunction; Humans; Kinetics; Male; Middle Aged; Muscle Re | 1995 |
Sildenafil in the treatment of erectile dysfunction.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aged; Coitus; Contraindications; Drug Interactions; Erectile Dy | 1998 |
Impotence responsive to glyceryl trinitrate.
Topics: Angina Pectoris; Arteriosclerosis; Depression; Erectile Dysfunction; Humans; Imipramine; Male; Middl | 1977 |
Drugs for impotence.
Topics: Alprostadil; Erectile Dysfunction; Humans; Male; Minoxidil; Nitroglycerin; Papaverine | 1992 |
Transcutaneous nitroglycerin in the treatment of erectile dysfunction in spinal cord injured.
Topics: Administration, Cutaneous; Adult; Aging; Erectile Dysfunction; Humans; Male; Middle Aged; Nitroglyce | 1992 |
Non-invasive management of impotence with transcutaneous nitroglycerin.
Topics: Administration, Cutaneous; Aged; Erectile Dysfunction; Headache; Humans; Male; Middle Aged; Nitrogly | 1992 |
[Angiography of the a. pudenda and its branches in erectile dysfunction. A modified angiographic technic and optimized use of vasodilator substances].
Topics: Arteries; Blood Flow Velocity; Catheterization, Peripheral; Erectile Dysfunction; Humans; Male; Nitr | 1991 |
[Nitroglycerin test for the diagnosis of erectile dysfunction].
Topics: Administration, Topical; Erectile Dysfunction; Humans; Male; Nitroglycerin; Penile Erection; Penis; | 1991 |
Re: Topical nitroglycerin: a potential treatment for impotence.
Topics: Administration, Topical; Erectile Dysfunction; Humans; Male; Nitroglycerin; Penile Erection; Penis; | 1990 |
Topical glyceryltrinitrate causes measurable penile arterial dilation in impotent men.
Topics: Blood Flow Velocity; Erectile Dysfunction; Humans; Male; Nitroglycerin; Penile Erection; Penis; Ultr | 1990 |
[Imaging of penile vascular anastomoses using color-coded Doppler ultrasound: comparison with CW Doppler ultrasound and clinical aspects].
Topics: Adult; Arteriovenous Shunt, Surgical; Blood Flow Velocity; Erectile Dysfunction; Follow-Up Studies; | 1990 |
Scleroderma and impotence: response to nitroglycerin applied to the fingers and penis.
Topics: Adult; Erectile Dysfunction; Fingers; Humans; Male; Nitroglycerin; Penis; Scleroderma, Systemic; Ski | 1990 |
Synthetic nitrovasodilators are effective, in vitro, in relaxing penile tissue from impotent men: the findings and their implications.
Topics: Dose-Response Relationship, Drug; Erectile Dysfunction; Humans; In Vitro Techniques; Isosorbide Dini | 1989 |
Pharmacoarteriography in the evaluation of impotence.
Topics: Adult; Aged; Angiography; Erectile Dysfunction; Humans; Male; Middle Aged; Nitroglycerin; Papaverine | 1987 |
Penile magnification pharmacoarteriography: details of intrapenile arterial anatomy.
Topics: Arterial Occlusive Diseases; Arteries; Collateral Circulation; Erectile Dysfunction; Humans; Iopamid | 1987 |