nitroglycerin has been researched along with Hypoxia in 81 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These findings suggest that coronary endothelium plays a pivotal role in preventing the hypoxia-induced impairment of nitroglycerin responsiveness, regardless of the animal species." | 7.85 | Responsiveness of Coronary Arteries to Nitroglycerin under Hypoxia: The Importance of the Endothelium. ( Okamura, T; Sakonjo, H; Shimosato, T; Tawa, M, 2017) |
| " The measurements were performed during normoxia and hypoxia before and after sublingual administration of the NO donor nitroglycerin, and were repeated on a second study day after topical administration of the COX-inhibitor diclofenac." | 7.83 | Lack of effect of nitroglycerin on the diameter response of larger retinal arterioles in normal persons during hypoxia. ( Bek, T; Kaya, MY; Petersen, L, 2016) |
| " Systemic administration of nitroglycerin (NTG) or mild hypoxia resulted in a decreased of c-fos expression in the dorsolateral part of the denervated neostriatum." | 7.71 | Fos and nitric oxide synthase in rat brain with chronic mesostriatal dopamine deficiency: effects of nitroglycerin and hypoxia. ( Appenzeller, O; Bazilyuk, OV; Maisky, VA; Oleshko, NN; Sagach, VF; Talanov, SA, 2002) |
| "This study investigated the effects of the Ca2+-sensitive K+ channel antagonist charybdotoxin on responses to the nitrosovasodilators nitroglycerin and sodium nitroprusside and on pulmonary pressor responses to ventilatory hypoxia in the isolated blood-perfused rat lung." | 7.69 | Effects of charybdotoxin on responses to nitrosovasodilators and hypoxia in the rat lung. ( Feng, CJ; Kadowitz, PJ; Kaye, AD; Nossaman, BD, 1997) |
| "To evaluate the potency of vasodilatory drugs in hypoxia, we studied the effects of nitroglycerin (NTG), prostaglandin E1 (PGE1), and hydralazine on porcine coronary artery constricted with endothelin-1 (ET-1) in both oxygenated and hypoxic conditions." | 7.69 | Hypoxia modifies the vasodilatory effects of nitroglycerin, prostaglandin E1, and hydralazine on isolated porcine coronary arteries. ( Fujihara, H; Fujiwara, N; Fukuda, S; Sakuma, K; Shimoji, K; Tanaka, T; Toriumi, T; Tsukui, A, 1994) |
| "The effects of ligustrazine and nitroglycerine on acute hypoxic pulmonary hypertension were observed in 10 anesthetized dogs." | 7.69 | [Effects of ligustrazine and nitroglycerine on acute hypoxic pulmonary hypertension in anesthetized dogs]. ( Cao, W; Guo, Z; Luo, W, 1994) |
| " In the current study, we compared the effects of inhaled nitric oxide and intravenous nitroglycerine on pulmonary and systemic haemodynamic responses as well as on gas exchange measurements in anaesthetized pigs whose pulmonary pressure was increased by hypoxia (FiO2 = 15%)." | 7.69 | Comparison of the effect of inhaled nitric oxide and intravenous nitroglycerine on hypoxia-induced pulmonary hypertension in pigs. ( Blaise, G; Charbonneau, M; Collet, JP; da Silva, P; Ducruet, T; Jacob, E; Salazkin, I; Troncy, E, 1996) |
| "Nitroglycerin-induced hypoxia does not compromise oxidative metabolism of myocardium as can be assessed by a concomitant decrease in coronary sinus lactate concentration." | 7.69 | Nitroglycerin-induced hypoxemia does not produce myocardial ischemia. ( Bilgen, F; Calişirişçi, U; Canik, S; Demirtaş, M; Kopman, EA; Ozler, A; Toraman, F; Yiğiter, B, 1997) |
| "To investigate the effects of hypoxia and nitroglycerin on pulmonary vascular tone, multipoint mean pulmonary arterial flow-pressure (Q-P relationship) plots were constructed by producing stepwise increments of pulmonary flow with a roller pump installed in a right ventricle-pulmonary artery shunt in 12 mongrel dogs under pentobarbital sodium anesthesia." | 7.68 | Pulmonary arterial flow-pressure characteristics in dogs--effects of hypoxia and nitroglycerin. ( Ikeda, M; Kunieda, T; Nakanishi, N; Yoshioka, T, 1992) |
| "Migraine was provoked in six (42%) patients by hypoxia, in three (21%) by NTG and in two (14%) by placebo." | 5.33 | Normobaric hypoxia and nitroglycerin as trigger factors for migraine. ( Agosti, RM; Bärtsch, P; Baumgartner, RW; Ferrari, MD; Sándor, PS; Schoonman, GG; Siccoli, M, 2006) |
| "Nitroglycerin (Ng) is a potent and short-acting coronary and systemic vasodilator, widely used in anginal pain treatment." | 5.26 | Arterial hypoxemia following the administration of sublingual nitroglycerin in patients with ischemic heart disease and pneumonia. ( Kuhnreich, E; Naschitz, JE; Yeshurun, D, 1981) |
| " Twenty persons with cardiovascular risk (mean age 50+/-2 years) were treated with atorvastatin (80 mg/day) and FMD/NMD was measured during normoxia, hypoxia and oxygen supplementation before, after 1 day and 3 months." | 5.13 | Effect of acute changes in oxygen tension on flow-mediated dilation. Relation to cardivascular risk. ( Frøbert, O; Holmager, P; Jensen, KM; Schmidt, EB; Simonsen, U, 2008) |
| "These findings suggest that coronary endothelium plays a pivotal role in preventing the hypoxia-induced impairment of nitroglycerin responsiveness, regardless of the animal species." | 3.85 | Responsiveness of Coronary Arteries to Nitroglycerin under Hypoxia: The Importance of the Endothelium. ( Okamura, T; Sakonjo, H; Shimosato, T; Tawa, M, 2017) |
| " The measurements were performed during normoxia and hypoxia before and after sublingual administration of the NO donor nitroglycerin, and were repeated on a second study day after topical administration of the COX-inhibitor diclofenac." | 3.83 | Lack of effect of nitroglycerin on the diameter response of larger retinal arterioles in normal persons during hypoxia. ( Bek, T; Kaya, MY; Petersen, L, 2016) |
| " Twenty-four anaesthetized and mechanically ventilated piglets (5-7 days old) were randomly divided into four groups: (1) group S, not hypoxic; (2) group C, nebulized saline after hypoxia; (3) group NTG, nebulized nitroglycerine after hypoxia; (4) group SNP, nebulized sodium nitroprusside after hypoxia." | 3.74 | Effect of inhalation of nebulized NO donor substance on acute hypoxic lung injury in newborn piglets. ( Huang, GY; Sun, B; Xia, HP; Zhu, JX, 2008) |
| " Diameter responses and interstitial lactate/pyruvate ratios were studied during 90 min hypoxia, hypoxia + reoxygenation (60 min), nitroglycerin (100 microm, 90 min), and nitroglycerin + wash-out (60 min)." | 3.73 | HSP20 phosphorylation and interstitial metabolites in hypoxia-induced dilation of swine coronary arteries. ( Buus, CL; Frøbert, O; Rembold, CM, 2005) |
| " Systemic administration of nitroglycerin (NTG) or mild hypoxia resulted in a decreased of c-fos expression in the dorsolateral part of the denervated neostriatum." | 3.71 | Fos and nitric oxide synthase in rat brain with chronic mesostriatal dopamine deficiency: effects of nitroglycerin and hypoxia. ( Appenzeller, O; Bazilyuk, OV; Maisky, VA; Oleshko, NN; Sagach, VF; Talanov, SA, 2002) |
| " In the current study, we compared the effects of inhaled nitric oxide and intravenous nitroglycerine on pulmonary and systemic haemodynamic responses as well as on gas exchange measurements in anaesthetized pigs whose pulmonary pressure was increased by hypoxia (FiO2 = 15%)." | 3.69 | Comparison of the effect of inhaled nitric oxide and intravenous nitroglycerine on hypoxia-induced pulmonary hypertension in pigs. ( Blaise, G; Charbonneau, M; Collet, JP; da Silva, P; Ducruet, T; Jacob, E; Salazkin, I; Troncy, E, 1996) |
| "Nitroglycerin-induced hypoxia does not compromise oxidative metabolism of myocardium as can be assessed by a concomitant decrease in coronary sinus lactate concentration." | 3.69 | Nitroglycerin-induced hypoxemia does not produce myocardial ischemia. ( Bilgen, F; Calişirişçi, U; Canik, S; Demirtaş, M; Kopman, EA; Ozler, A; Toraman, F; Yiğiter, B, 1997) |
| "This study investigated the effects of the Ca2+-sensitive K+ channel antagonist charybdotoxin on responses to the nitrosovasodilators nitroglycerin and sodium nitroprusside and on pulmonary pressor responses to ventilatory hypoxia in the isolated blood-perfused rat lung." | 3.69 | Effects of charybdotoxin on responses to nitrosovasodilators and hypoxia in the rat lung. ( Feng, CJ; Kadowitz, PJ; Kaye, AD; Nossaman, BD, 1997) |
| "To evaluate the potency of vasodilatory drugs in hypoxia, we studied the effects of nitroglycerin (NTG), prostaglandin E1 (PGE1), and hydralazine on porcine coronary artery constricted with endothelin-1 (ET-1) in both oxygenated and hypoxic conditions." | 3.69 | Hypoxia modifies the vasodilatory effects of nitroglycerin, prostaglandin E1, and hydralazine on isolated porcine coronary arteries. ( Fujihara, H; Fujiwara, N; Fukuda, S; Sakuma, K; Shimoji, K; Tanaka, T; Toriumi, T; Tsukui, A, 1994) |
| "The effects of ligustrazine and nitroglycerine on acute hypoxic pulmonary hypertension were observed in 10 anesthetized dogs." | 3.69 | [Effects of ligustrazine and nitroglycerine on acute hypoxic pulmonary hypertension in anesthetized dogs]. ( Cao, W; Guo, Z; Luo, W, 1994) |
| " The aims of this study were to compare in the rat isolated perfused lung preparation, the dilator actions of nicorandil, pinacidil and nitroglycerin on the hypoxic pulmonary pressure response with or without hypercapnic acidosis and to investigate the possible involvement of K channels and EDRF in these effects." | 3.69 | Comparison of the effects of nicorandil, pinacidil and nitroglycerin on hypoxic and hypercapnic pulmonary vasoconstriction in the isolated perfused lung of rat. ( Advenier, C; Dumas, JP; Dumas, M; Giudicelli, JF; Rochette, L, 1996) |
| "To investigate the effects of hypoxia and nitroglycerin on pulmonary vascular tone, multipoint mean pulmonary arterial flow-pressure (Q-P relationship) plots were constructed by producing stepwise increments of pulmonary flow with a roller pump installed in a right ventricle-pulmonary artery shunt in 12 mongrel dogs under pentobarbital sodium anesthesia." | 3.68 | Pulmonary arterial flow-pressure characteristics in dogs--effects of hypoxia and nitroglycerin. ( Ikeda, M; Kunieda, T; Nakanishi, N; Yoshioka, T, 1992) |
| " In arteries mounted in vitro for measurements of isometric tension, 20 min of hypoxia (bath oxygen partial pressure, approximately 15 Torr) significantly increased cyclic GMP levels from 16 to 32, from 15 to 25 and from 20 to 38 pmol/g in rabbit common carotid, internal carotid and basilar arteries." | 3.68 | Effects of methylene blue on hypoxic cerebral vasodilatation in the rabbit. ( Aubineau, P; Ignarro, L; Lee, J; Pearce, WJ; Reynier-Rebuffel, AM; Seylaz, J, 1990) |
| "The myocardial protective effect of nicorandil, N-(2-hydroxyethyl) nicotinamide nitrate ester, against hypoxia was examined in comparison with that of nitroglycerin in 22 open chest dogs." | 3.67 | Examination of the direct effects of antianginal agents on the hypoxic canine myocardium. ( Hattori, S; Kojima, S; Miyamori, R; Miyazaki, T; Mori, H; Nagata, M; Nakamura, Y; Takahashi, M, 1987) |
| "Although menopause was not associated with vascular impairment, short-term improvement in vascular function was observed in those using menopausal hormonal therapy." | 1.91 | Effect of menopause and age on vascular impairment. ( Aittokallio, J; Hautajärvi, T; Heinonen, O; Kalleinen, N; Polo, O; Raitakari, O; Riskumäki, M; Saaresranta, T; Vahlberg, T, 2023) |
| "Immune escape is a fundamental trait of cancer in which mechanistic knowledge is incomplete." | 1.40 | A mechanism of hypoxia-mediated escape from adaptive immunity in cancer cells. ( Barsoum, IB; Graham, CH; Siemens, DR; Smallwood, CA, 2014) |
| "Migraine was provoked in six (42%) patients by hypoxia, in three (21%) by NTG and in two (14%) by placebo." | 1.33 | Normobaric hypoxia and nitroglycerin as trigger factors for migraine. ( Agosti, RM; Bärtsch, P; Baumgartner, RW; Ferrari, MD; Sándor, PS; Schoonman, GG; Siccoli, M, 2006) |
| "Worsening nocturnal hypoxemia, measured as nocturnal oxygen saturation nadir or percentage of sleep time spent in hypoxemia (< 90% hemoglobin oxygen saturation), predicted increased interventricular septum thickness (corrected for age and body mass index), prolonged isovolumetric relaxation time, decreased ratio between peak early and late mitral flow velocities, as well as reduced endothelium-dependent dilatory capacity of the brachial artery (all relationships corrected for cofactor age and with p < 0." | 1.31 | Impairment of vascular endothelial function and left ventricular filling : association with the severity of apnea-induced hypoxemia during sleep. ( Caidahl, K; Hedner, J; Kraiczi, H; Peker, Y; Samuelsson, A, 2001) |
| "Nitroglycerin was administrated either by inhalation or by infusion." | 1.30 | Effects of inhalation of nitroglycerin on hypoxic pulmonary vasoconstriction. ( Bando, M; Ishii, Y; Kitamura, S; Ohno, S, 1998) |
| " The effects of cytochrome P-450 inhibitor [2-dimethylaminoethyl-2,2-diphenyl-n-pentanoate (SKF-525A) and metyrapone] on the response of rabbit aortic rings to GTN was determined by recording cumulative GTN dose-response curves in the presence of either or both inhibitors." | 1.29 | Lack of evidence for the involvement of cytochrome P-450 or other hemoproteins in metabolic activation of glyceryl trinitrate in rabbit aorta. ( Brien, JF; Liu, Z; Marks, GS; McLaughlin, BE; Nakatsu, K, 1993) |
| "Ten episodic cluster headache patients in their active cluster period, ten patients in remission and five control subjects were monitored for minute to minute changes in oxygen saturation (SaO2) and pulse rate before and after nitroglycerin (NTG) administration." | 1.28 | Association of sustained oxyhemoglobin desaturation and onset of cluster headache attacks. ( Kudrow, DB; Kudrow, L, 1990) |
| "Anoxia has been shown to potentiate the constrictor effects of 5-hydroxytryptamine (5HT) in isolated vascular tissue." | 1.27 | Effects of nitroglycerin, dipyridamole, nifedipine, verapamil and diltiazem on canine coronary arterial rings contracted with 5-hydroxytryptamine and anoxia. ( Balkon, J; Barrett, JA; DePaul Lynch, V; Smith, RD; Wolf, PS, 1986) |
| "Nitroglycerin (Ng) is a potent and short-acting coronary and systemic vasodilator, widely used in anginal pain treatment." | 1.26 | Arterial hypoxemia following the administration of sublingual nitroglycerin in patients with ischemic heart disease and pneumonia. ( Kuhnreich, E; Naschitz, JE; Yeshurun, D, 1981) |
| "If bronchospasmolytic agents are added, hypoxemia can be prohibited." | 1.26 | [The distribution of ventilation and perfusion in the obstructive syndrome during nitroglycerin and bronchospasmolytic therapy]. ( Borkenstein, J, 1979) |
| "Influence of oxygen deficiency and vasodilating drugs on coronary arterial tonus was investigated." | 1.26 | Local specificity in responses of canine coronary vessels to oxygen deficiency and antianginal drugs. ( Honda, F; Kamitani, T; Katsuki, S; Mori, J; Nakano, K, 1977) |
| " The NE dose-response curves shifted to the left." | 1.25 | Potentiation of the contractile effects of norepinephrine by hypoxia. ( Cooper, T; Epstein, SE; Kent, KM, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (46.91) | 18.7374 |
| 1990's | 20 (24.69) | 18.2507 |
| 2000's | 11 (13.58) | 29.6817 |
| 2010's | 10 (12.35) | 24.3611 |
| 2020's | 2 (2.47) | 2.80 |
| Authors | Studies |
|---|---|
| Petrucci, E | 1 |
| Cofini, V | 1 |
| Pizzi, B | 1 |
| Necozione, S | 1 |
| Marinangeli, F | 1 |
| Aittokallio, J | 1 |
| Saaresranta, T | 1 |
| Riskumäki, M | 1 |
| Hautajärvi, T | 1 |
| Vahlberg, T | 1 |
| Polo, O | 1 |
| Heinonen, O | 1 |
| Raitakari, O | 1 |
| Kalleinen, N | 1 |
| Robb, KP | 1 |
| Cotechini, T | 1 |
| Allaire, C | 1 |
| Sperou, A | 1 |
| Graham, CH | 5 |
| Lewis, NCS | 1 |
| Bain, AR | 1 |
| Wildfong, KW | 1 |
| Green, DJ | 1 |
| Ainslie, PN | 1 |
| Gu, Z | 1 |
| Xin, L | 1 |
| Wang, Z | 1 |
| Wang, J | 1 |
| Barsoum, IB | 2 |
| Smallwood, CA | 1 |
| Siemens, DR | 2 |
| Mosing, M | 1 |
| Kutter, AP | 1 |
| Iff, S | 1 |
| Raszplewicz, J | 1 |
| Mauch, J | 1 |
| Bohm, SH | 1 |
| Tusman, G | 1 |
| Arif, S | 1 |
| Borgognone, A | 1 |
| Lin, EL | 1 |
| O'Sullivan, AG | 1 |
| Sharma, V | 1 |
| Drury, NE | 1 |
| Menon, A | 1 |
| Nightingale, P | 1 |
| Mascaro, J | 1 |
| Bonser, RS | 1 |
| Horowitz, JD | 1 |
| Feelisch, M | 1 |
| Frenneaux, MP | 1 |
| Madhani, M | 1 |
| Kaya, MY | 1 |
| Petersen, L | 1 |
| Bek, T | 1 |
| Tawa, M | 1 |
| Shimosato, T | 1 |
| Sakonjo, H | 1 |
| Okamura, T | 1 |
| Hu, N | 1 |
| Sheikhi, AK | 1 |
| Chung, E | 1 |
| Frederiksen, LJ | 1 |
| Pross, H | 1 |
| Xia, HP | 1 |
| Huang, GY | 1 |
| Zhu, JX | 1 |
| Sun, B | 1 |
| Renaud, SJ | 1 |
| Donegani, E | 1 |
| GABEL, LP | 1 |
| WINBURY, MM | 1 |
| ROWE, H | 1 |
| GRANDY, RP | 1 |
| MacLeod, DB | 1 |
| Cortinez, LI | 1 |
| Keifer, JC | 1 |
| Cameron, D | 1 |
| Wright, DR | 1 |
| White, WD | 1 |
| Moretti, EW | 1 |
| Radulescu, LR | 1 |
| Somma, J | 1 |
| Frøbert, O | 2 |
| Buus, CL | 1 |
| Rembold, CM | 1 |
| Karaaslan, P | 1 |
| Dönmez, A | 1 |
| Arslan, G | 1 |
| Schoonman, GG | 1 |
| Sándor, PS | 1 |
| Agosti, RM | 1 |
| Siccoli, M | 1 |
| Bärtsch, P | 1 |
| Ferrari, MD | 1 |
| Baumgartner, RW | 1 |
| Belkacemi, L | 1 |
| Bainbridge, SA | 1 |
| Dickinson, MA | 1 |
| Smith, GN | 1 |
| Holmager, P | 1 |
| Jensen, KM | 1 |
| Schmidt, EB | 1 |
| Simonsen, U | 1 |
| Watanabe, S | 1 |
| D'Oliveira, M | 1 |
| Sykes, MK | 1 |
| Chakrabarti, MK | 1 |
| Orchard, C | 1 |
| Keslin, J | 1 |
| Weygandt, GR | 2 |
| Kopman, EA | 3 |
| Ludbrook, PA | 1 |
| Naschitz, JE | 1 |
| Kuhnreich, E | 1 |
| Yeshurun, D | 1 |
| Casthely, PA | 1 |
| Lear, S | 1 |
| Cottrell, JE | 1 |
| Lear, E | 1 |
| Naeije, R | 1 |
| Mélot, C | 1 |
| Mols, P | 1 |
| Hallemans, R | 1 |
| Fukuda, S | 2 |
| Sakuma, K | 2 |
| Tsukui, A | 2 |
| Fujiwara, N | 2 |
| Tanaka, T | 2 |
| Fujihara, H | 1 |
| Toriumi, T | 1 |
| Shimoji, K | 2 |
| Wang, P | 3 |
| Ba, ZF | 3 |
| Chaudry, IH | 3 |
| Cao, W | 1 |
| Luo, W | 1 |
| Guo, Z | 1 |
| Liu, Z | 1 |
| Brien, JF | 1 |
| Marks, GS | 1 |
| McLaughlin, BE | 1 |
| Nakatsu, K | 1 |
| Dumas, M | 1 |
| Dumas, JP | 1 |
| Rochette, L | 1 |
| Advenier, C | 1 |
| Giudicelli, JF | 1 |
| Samoĭlenko, AV | 1 |
| Troncy, E | 1 |
| Jacob, E | 1 |
| da Silva, P | 1 |
| Ducruet, T | 1 |
| Collet, JP | 1 |
| Salazkin, I | 1 |
| Charbonneau, M | 1 |
| Blaise, G | 1 |
| Nossaman, BD | 1 |
| Kaye, AD | 1 |
| Feng, CJ | 1 |
| Kadowitz, PJ | 1 |
| Toraman, F | 1 |
| Calişirişçi, U | 1 |
| Demirtaş, M | 1 |
| Bilgen, F | 1 |
| Ozler, A | 1 |
| Canik, S | 1 |
| Yiğiter, B | 1 |
| Bando, M | 1 |
| Ishii, Y | 1 |
| Kitamura, S | 1 |
| Ohno, S | 1 |
| Kraiczi, H | 1 |
| Caidahl, K | 1 |
| Samuelsson, A | 1 |
| Peker, Y | 1 |
| Hedner, J | 1 |
| Agvald, P | 1 |
| Adding, LC | 1 |
| Artlich, A | 1 |
| Persson, MG | 1 |
| Gustafsson, LE | 1 |
| Maisky, VA | 1 |
| Oleshko, NN | 1 |
| Bazilyuk, OV | 1 |
| Talanov, SA | 1 |
| Sagach, VF | 1 |
| Appenzeller, O | 1 |
| Hjalmarson, AC | 1 |
| Waldenström, AP | 1 |
| Bauer, S | 1 |
| Ferguson, TB | 1 |
| Kaverina, NV | 1 |
| Chumburidze, VB | 1 |
| Danilevicius, Z | 1 |
| Hales, CA | 1 |
| Westphal, D | 1 |
| Bonoron-Adèle, S | 1 |
| Besse, P | 1 |
| Tariosse, L | 1 |
| Bricaud, H | 1 |
| Borkenstein, J | 1 |
| Kamitani, T | 1 |
| Nakano, K | 1 |
| Mori, J | 1 |
| Katsuki, S | 1 |
| Honda, F | 1 |
| Brückner, JB | 1 |
| Gmeiner, R | 2 |
| Knapp, E | 1 |
| Schwingshackl, H | 1 |
| Dienstl, F | 1 |
| Brodie, BR | 1 |
| Cuck, L | 1 |
| Klausner, S | 1 |
| Grossman, W | 1 |
| Parmley, W | 1 |
| D'Angeli, MA | 1 |
| Goetzman, BW | 1 |
| Nakanishi, N | 1 |
| Yoshioka, T | 1 |
| Kunieda, T | 1 |
| Ikeda, M | 1 |
| Gaál, J | 1 |
| Vértesi, C | 2 |
| Knopf, E | 2 |
| Körmöczy, PS | 2 |
| Kudrow, L | 1 |
| Kudrow, DB | 1 |
| Pearce, WJ | 1 |
| Reynier-Rebuffel, AM | 1 |
| Lee, J | 1 |
| Aubineau, P | 1 |
| Ignarro, L | 1 |
| Seylaz, J | 1 |
| Cherry, PD | 1 |
| Omar, HA | 1 |
| Farrell, KA | 1 |
| Stuart, JS | 1 |
| Wolin, MS | 1 |
| Zierhut, W | 1 |
| Zimmer, HG | 1 |
| Leitold, M | 1 |
| Hader, S | 1 |
| Nakamura, Y | 1 |
| Kojima, S | 1 |
| Mori, H | 1 |
| Nagata, M | 1 |
| Miyazaki, T | 1 |
| Miyamori, R | 1 |
| Hattori, S | 1 |
| Takahashi, M | 1 |
| Berthelsen, P | 1 |
| St Haxholdt, O | 1 |
| Husum, B | 1 |
| Rasmussen, JP | 1 |
| Barrett, JA | 1 |
| DePaul Lynch, V | 1 |
| Balkon, J | 1 |
| Smith, RD | 1 |
| Wolf, PS | 1 |
| Bojar, RM | 1 |
| Rastegar, H | 1 |
| Payne, DD | 1 |
| Harkness, SH | 1 |
| England, MR | 1 |
| Stetz, JJ | 1 |
| Weiner, B | 1 |
| Cleveland, RJ | 1 |
| Watanabe, K | 1 |
| Kimura, Y | 1 |
| Abiko, Y | 3 |
| Dodek, A | 1 |
| Kassebaum, DG | 1 |
| Griswold, HE | 1 |
| Virtanen, KS | 1 |
| Meisel, M | 1 |
| Meisel, P | 1 |
| Urbaszek, W | 1 |
| Tronicke, E | 1 |
| Modersohn, D | 1 |
| Uhlich, C | 1 |
| Günther, K | 1 |
| Pankau, H | 1 |
| Guy, CR | 1 |
| Eliot, RS | 1 |
| Minamidate, A | 1 |
| Takano, S | 2 |
| Hashikawa, T | 2 |
| Hayashi, A | 1 |
| Thorn, W | 1 |
| Lochner, W | 1 |
| Froment, R | 1 |
| Kent, KM | 1 |
| Epstein, SE | 1 |
| Cooper, T | 1 |
| Hickam, JB | 1 |
| Frayser, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Study to Test the Feasibility of IV Injected Tc-99m-tilmanocept for Imaging of M2-like Tumour Associated Macrophages in Metastatic Melanoma[NCT04663126] | Early Phase 1 | 5 participants (Actual) | Interventional | 2021-02-01 | Terminated (stopped due to after inclusion of 5 patients, tracer had low uptake (kidney/liver)) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for nitroglycerin and Hypoxia
| Article | Year |
|---|---|
[New therapeutic agents and hypoxic pulmonary vasoconstriction].
Topics: Aminophylline; Anesthetics; Bronchodilator Agents; Humans; Hypoxia; Lung; Lung Diseases, Obstructive | 1983 |
Antianginal drugs.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anabolic Agents; Angina Pectoris; Animals; An | 1979 |
[Is adenosine the mediator for the regulation of the coronary circulation and for the effect of coronarodilators? Review].
Topics: Adenosine; Adenosine Triphosphate; Aminohydrolases; Aminophylline; Animals; Calcium; Carbon Dioxide; | 1974 |
The pathophysiologic vulnerability of the subendocardium of the left ventricle.
Topics: Arrhythmias, Cardiac; Capillaries; Cardiomegaly; Coronary Disease; Coronary Vessels; Endocardium; He | 1973 |
3 trials available for nitroglycerin and Hypoxia
| Article | Year |
|---|---|
Acute hypoxaemia and vascular function in healthy humans.
Topics: Acute Disease; Adult; Blood Flow Velocity; Brachial Artery; British Columbia; Endothelium, Vascular; | 2017 |
Effect of acute changes in oxygen tension on flow-mediated dilation. Relation to cardivascular risk.
Topics: Administration, Inhalation; Adult; Atorvastatin; Brachial Artery; Cardiovascular Diseases; Cholester | 2008 |
[Angina pectoris].
Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Angiography; Coronary Circulation; Coronary Vess | 1972 |
74 other studies available for nitroglycerin and Hypoxia
| Article | Year |
|---|---|
Arterial Blood Gas and Rotational Thromboelastometry Parameters in Healthy Rescuers Incidentally Exposed to Nitroglycerin, Nitrogen Compounds, and Combustion Products.
Topics: Acidosis, Respiratory; Adult; Blood Coagulation Disorders; Blood Gas Analysis; Humans; Hypercapnia; | 2022 |
Effect of menopause and age on vascular impairment.
Topics: Brachial Artery; Cardiovascular Diseases; Endothelium, Vascular; Female; Humans; Hypoxia; Menopause; | 2023 |
Inflammation-induced fetal growth restriction in rats is associated with increased placental HIF-1α accumulation.
Topics: Animals; Disease Models, Animal; Female; Fetal Growth Retardation; Gene Expression Regulation; Gesta | 2017 |
Intravenous anesthesia with nitroglycerin inhalation for surgical abortion in a patient with severe congenital heart disease and low oxygen saturation: A case report.
Topics: Abortion, Induced; Adult; Anesthesia, Intravenous; Blood Gas Analysis; Blood Pressure Determination; | 2018 |
A mechanism of hypoxia-mediated escape from adaptive immunity in cancer cells.
Topics: Adaptive Immunity; Animals; Apoptosis; B7-H1 Antigen; Cell Line, Tumor; Cytotoxicity, Immunologic; F | 2014 |
The effects of cardiac output and pulmonary arterial hypertension on volumetric capnography derived-variables during normoxia and hypoxia.
Topics: Anesthesia; Animals; Capnography; Carbon Monoxide; Cardiac Output; Dobutamine; Hemodynamics; Hyperte | 2015 |
Role of aldehyde dehydrogenase in hypoxic vasodilator effects of nitrite in rats and humans.
Topics: Aged; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Animals; Arteries; C | 2015 |
Lack of effect of nitroglycerin on the diameter response of larger retinal arterioles in normal persons during hypoxia.
Topics: Administration, Topical; Adult; Arterioles; Blood Pressure; Cyclooxygenase Inhibitors; Diclofenac; E | 2016 |
Responsiveness of Coronary Arteries to Nitroglycerin under Hypoxia: The Importance of the Endothelium.
Topics: Animals; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Hypoxia; | 2017 |
Hypoxia increases tumor cell shedding of MHC class I chain-related molecule: role of nitric oxide.
Topics: Adenocarcinoma; Animals; Cells, Cultured; Histocompatibility Antigens Class I; Humans; Hypoxia; Immu | 2008 |
Effect of inhalation of nebulized NO donor substance on acute hypoxic lung injury in newborn piglets.
Topics: Acute Lung Injury; Animals; Animals, Newborn; Bronchoalveolar Lavage Fluid; Hypoxia; Leukocyte Count | 2008 |
Glyceryl trinitrate inhibits hypoxia-induced release of soluble fms-like tyrosine kinase-1 and endoglin from placental tissues.
Topics: Antigens, CD; Chorionic Villi; Endoglin; Female; Gene Expression Regulation; Gene Knockdown Techniqu | 2011 |
[Nitrates at high altitude, that is the inappropriate use of a drug].
Topics: Administration, Cutaneous; Altitude Sickness; Angina Pectoris; Brain Edema; Disorders of Excessive S | 2011 |
THE EFFECT OF SEVERAL PHARMACOLOGICAL AGENTS UPON RB86 UPTAKE BY THE PERFUSED DOG HINDLIMB.
Topics: Acetylcholine; Animals; Blood Circulation; Cell Membrane Permeability; Dogs; Epinephrine; Hindlimb; | 1964 |
The desaturation response time of finger pulse oximeters during mild hypothermia.
Topics: Adult; Anthropometry; Fingers; Humans; Hypothermia; Hypoxia; Male; Monitoring, Physiologic; Nitrogly | 2005 |
HSP20 phosphorylation and interstitial metabolites in hypoxia-induced dilation of swine coronary arteries.
Topics: Animals; Blood Glucose; Coronary Vessels; Dilatation, Pathologic; Heat-Shock Proteins; HSP20 Heat-Sh | 2005 |
Severe hypoxaemia following intravenous nitroglycerine administration in an obese patient: case report.
Topics: Adult; Anesthesia, General; Diabetes Mellitus; Humans; Hypertension; Hypoxia; Infusions, Intravenous | 2005 |
Normobaric hypoxia and nitroglycerin as trigger factors for migraine.
Topics: Adult; Female; Humans; Hypoxia; Male; Migraine Disorders; Nitroglycerin; Pain Measurement; Risk Asse | 2006 |
Glyceryl trinitrate inhibits hypoxia/reoxygenation-induced apoptosis in the syncytiotrophoblast of the human placenta: therapeutic implications for preeclampsia.
Topics: Aldehydes; Apoptosis; Blotting, Western; Caspase 3; Collagen Type XI; Female; Humans; Hypoxia; Immun | 2007 |
Depression of hypoxic pulmonary vasoconstriction by sodium nitroprusside and nitroglycerine.
Topics: Animals; Blood Pressure; Carbon Dioxide; Depression, Chemical; Dogs; Ferricyanides; Hypoxia; Nitrogl | 1981 |
Mechanism of nitroglycerin-induced hypoxemia.
Topics: Cardiac Catheterization; Coronary Disease; Hemodynamics; Humans; Hypoxia; Male; Middle Aged; Nitrogl | 1980 |
Arterial hypoxemia following the administration of sublingual nitroglycerin in patients with ischemic heart disease and pneumonia.
Topics: Adult; Aged; Coronary Disease; Female; Femoral Artery; Humans; Hypoxia; Male; Middle Aged; Mouth Flo | 1981 |
Intrapulmonary shunting during induced hypotension.
Topics: Adult; Carbon Dioxide; Female; Hemodynamics; Humans; Hypotension, Controlled; Hypoxia; Intraoperativ | 1982 |
Effects of vasodilators on hypoxic pulmonary vasoconstriction in normal man.
Topics: Adult; Female; Hemodynamics; Humans; Hypoxia; Male; Nifedipine; Nitroglycerin; Nitroprusside; Oxygen | 1982 |
Hypoxia modifies the vasodilatory effects of nitroglycerin, prostaglandin E1, and hydralazine on isolated porcine coronary arteries.
Topics: Alprostadil; Analysis of Variance; Animals; Coronary Vessels; Cyclic AMP; Cyclic GMP; Endothelins; H | 1994 |
ATP-MgCl2 restores depressed endothelial cell function after hemorrhagic shock and resuscitation.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Endothelium, Vascular; Hemodynamics; Hypoxia; Male; | 1995 |
[Effects of ligustrazine and nitroglycerine on acute hypoxic pulmonary hypertension in anesthetized dogs].
Topics: Acute Disease; Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Female; Hypertension, Pulmon | 1994 |
Endothelial cell dysfunction occurs very early following trauma-hemorrhage and persists despite fluid resuscitation.
Topics: Acetylcholine; Animals; Blood Pressure; Endothelium, Vascular; Hematocrit; Hemorrhage; Hypoxia; Isot | 1993 |
Endothelial cell dysfunction occurs after hemorrhage in nonheparinized but not in preheparinized models.
Topics: Acetylcholine; Animals; Endothelium, Vascular; Heparin; Hypoxia; In Vitro Techniques; Male; Nitric O | 1993 |
Lack of evidence for the involvement of cytochrome P-450 or other hemoproteins in metabolic activation of glyceryl trinitrate in rabbit aorta.
Topics: Animals; Aorta; Biotransformation; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hemeproteins; Hy | 1993 |
Comparison of the effects of nicorandil, pinacidil and nitroglycerin on hypoxic and hypercapnic pulmonary vasoconstriction in the isolated perfused lung of rat.
Topics: Acidosis; Animals; Guanidines; Hypercapnia; Hypoxia; In Vitro Techniques; Lung; Male; Niacinamide; N | 1996 |
[Regular increase in the part of blood flow from the anterior vena cava in total venous return during systemic cardiovascular reactions].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Pressure; | 1996 |
Comparison of the effect of inhaled nitric oxide and intravenous nitroglycerine on hypoxia-induced pulmonary hypertension in pigs.
Topics: Administration, Inhalation; Animals; Female; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Infusio | 1996 |
Effects of charybdotoxin on responses to nitrosovasodilators and hypoxia in the rat lung.
Topics: Administration, Inhalation; Animals; Calcium; Charybdotoxin; Gases; Hypoxia; In Vitro Techniques; Lu | 1997 |
Nitroglycerin-induced hypoxemia does not produce myocardial ischemia.
Topics: Adult; Aged; Female; Humans; Hypoxia; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Vasodil | 1997 |
Effects of inhalation of nitroglycerin on hypoxic pulmonary vasoconstriction.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Blood Pressure; Cardiac Output; Disease M | 1998 |
Impairment of vascular endothelial function and left ventricular filling : association with the severity of apnea-induced hypoxemia during sleep.
Topics: Adult; Aged; Blood Flow Velocity; Brachial Artery; Cross-Sectional Studies; Diastole; Echocardiograp | 2001 |
Mechanisms of nitric oxide generation from nitroglycerin and endogenous sources during hypoxia in vivo.
Topics: Animals; Hypoxia; Lung; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroglycerin; | 2002 |
Fos and nitric oxide synthase in rat brain with chronic mesostriatal dopamine deficiency: effects of nitroglycerin and hypoxia.
Topics: Animals; Brain; Brain Stem; Chronic Disease; Dopamine; Hypoxia; Male; NADPH Dehydrogenase; Neostriat | 2002 |
Myocardial metabolism in angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Coronary Disease; Humans; Hypoxia; Myocardium | 1977 |
Arterial hypoxemia following the administration of sublingual nitroglycerin.
Topics: Administration, Oral; Adult; Carbon Dioxide; Coronary Artery Bypass; Coronary Disease; Female; Hemod | 1978 |
Hypoxemia from sublingual nitroglycerin.
Topics: Angina Pectoris; Blood Vessels; Humans; Hypoxia; Nitroglycerin; Oxygen Consumption; Partial Pressure | 1979 |
Hypoxemia following the administration of sublingual nitroglycerin.
Topics: Adult; Animals; Blood Pressure; Dogs; Female; Humans; Hypoxia; Lung Diseases, Obstructive; Male; Nit | 1978 |
[Effect of nitrate derivatives on the contractility and relaxation of papillary muscle in hypoxia and reoxygenation].
Topics: Animals; Cats; Ferricyanides; Hypoxia; In Vitro Techniques; Myocardial Contraction; Nitroglycerin; N | 1979 |
[The distribution of ventilation and perfusion in the obstructive syndrome during nitroglycerin and bronchospasmolytic therapy].
Topics: Aged; Fenoterol; Humans; Hypertension, Pulmonary; Hypoxia; Lung; Lung Diseases, Obstructive; Male; M | 1979 |
Local specificity in responses of canine coronary vessels to oxygen deficiency and antianginal drugs.
Topics: Adenosine; Angina Pectoris; Animals; Blood Pressure; Coronary Vessels; Cyanides; Dogs; Hypoxia; In V | 1977 |
[Pathophysiological mechanisms in stagnant hypoxia with special reference to myocardial ischaemia (author's transl)].
Topics: Adenosine Triphosphate; Anesthetics; Coronary Disease; Energy Metabolism; Glucose; Heart; Heart Arre | 1977 |
Hypoxic, isolated rat heart: hemodynamic and metabolic effects of nitroglycerin.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Cardiac Output; Heart; Hypoxia; In Vitro Tech | 1975 |
Effects of sodium nitroprusside and nitroglycerin on tension prolongation of cat papillary muscle during recovery from hypoxia.
Topics: Animals; Cats; Compliance; Culture Techniques; Elasticity; Ferricyanides; Hypoxia; Myocardial Contra | 1976 |
Vasorelaxation by nitroglycerin of the isolated porcine coronary artery during hypoxia.
Topics: Animals; Coronary Vessels; Cyclic GMP; Hypoxia; In Vitro Techniques; Muscle Relaxation; Muscle, Smoo | 1992 |
Intratracheal administration of pulmonary vasodilator agents.
Topics: Animals; Animals, Newborn; Epinephrine; Hemodynamics; Histamine; Hypoxia; Injections, Intravenous; I | 1992 |
Pulmonary arterial flow-pressure characteristics in dogs--effects of hypoxia and nitroglycerin.
Topics: Animals; Blood Pressure; Dogs; Hypoxia; Nitroglycerin; Pulmonary Artery; Pulmonary Circulation; Vaso | 1992 |
Comparison of the cardioprotective effect of nitroglycerin, molsidomine and SIN-1 in rats with cardiac hypoxia.
Topics: Animals; Antihypertensive Agents; Heart Diseases; Hypoxia; Molsidomine; Nitroglycerin; Rats | 1990 |
Effect of nitroglycerin and a nitroglycerin-like substance in isoprenaline (ISO) necrosis and hypoxia.
Topics: Animals; Hypoxia; Isoproterenol; Molsidomine; Necrosis; Nitroglycerin; Rats | 1990 |
Association of sustained oxyhemoglobin desaturation and onset of cluster headache attacks.
Topics: Adult; Cluster Headache; Female; Humans; Hypoxia; Male; Middle Aged; Monitoring, Physiologic; Nitrog | 1990 |
Effects of methylene blue on hypoxic cerebral vasodilatation in the rabbit.
Topics: Animals; Cerebrovascular Circulation; Cyclic GMP; Drug Interactions; Hypoxia; Injections, Intravenou | 1990 |
Superoxide anion inhibits cGMP-associated bovine pulmonary arterial relaxation.
Topics: Aminoquinolines; Animals; Anions; Cattle; Cyclic GMP; Ditiocarb; Hydrogen Peroxide; Hypoxia; Isoprot | 1990 |
Effect of calcium antagonists and other drugs on the hypoxia-induced increase in rat right ventricular pressure.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Captopril; Female; Heart; Heart Rate; Heart Ventr | 1989 |
[Influence of antianginal drugs on Lypressin induced T-wave enhancement in the electrocardiogram of the rat].
Topics: Administration, Oral; Angina Pectoris; Animals; Coronary Vasospasm; Electrocardiography; Hypoxia; Is | 1986 |
Examination of the direct effects of antianginal agents on the hypoxic canine myocardium.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cardiomyopathies; Coronary Circulation; Dogs | 1987 |
PEEP reverses nitroglycerin-induced hypoxemia following coronary artery bypass surgery.
Topics: Coronary Artery Bypass; Hemodynamics; Humans; Hypoxia; Intraoperative Complications; Nitroglycerin; | 1986 |
Effects of nitroglycerin, dipyridamole, nifedipine, verapamil and diltiazem on canine coronary arterial rings contracted with 5-hydroxytryptamine and anoxia.
Topics: Animals; Arteries; Calcium; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Dipyridamole; Dog | 1986 |
Methemoglobinemia from intravenous nitroglycerin: a word of caution.
Topics: Aged; Coronary Artery Bypass; Humans; Hypoxia; Infusions, Intravenous; Intraoperative Complications; | 1987 |
Nifedipine increases oxygen saturation level of myoglobin in the rat heart during hypoxia.
Topics: Animals; Dipyridamole; Heart; Hypoxia; Male; Myocardium; Myoglobin; Nifedipine; Nitroglycerin; Rats; | 1986 |
Stress electrocardiography in the evaluation of aortocoronary bypass surgery.
Topics: Adult; Angina Pectoris; Aortography; Coronary Angiography; Coronary Artery Bypass; Coronary Disease; | 1973 |
Phasic myocardial blood content. An experimental study on effects of hypoxaemia, ischaemia and coronary drugs.
Topics: Animals; Anti-Arrhythmia Agents; Biopsy; Cardiac Output; Chromium Radioisotopes; Coronary Circulatio | 1974 |
Effect of nitroglycerin on the mechanical and metabolic performance of the isolated aerobic and hypoxic rat heart.
Topics: Animals; Aorta; Blood Pressure; Buffers; Cardiac Output; Heart; Heart Rate; Heart Ventricles; Hypoxi | 1974 |
[Effects of coronary vaso dilators on myocardial survival time in the rat under anoxia conditions].
Topics: Animals; Coronary Circulation; Dipyridamole; Female; Heart; Hypoxia; Male; Myocardium; Nitroglycerin | 1974 |
Transmural gradient of NAD-NADPH ratio in their canine left ventricular myocardium, and effects of coronary dilators on the transmural gradient.
Topics: Animals; Coronary Vessels; Dipyridamole; Dogs; Female; Heart Ventricles; Hypoxia; Male; Myocardium; | 1973 |
Redox state of nicotinamide-adenine dinucleotide in the inner and outer layers of canine left ventricle, and effects of coronary dilators on the redox state.
Topics: Animals; Coronary Vessels; Dipyridamole; Dogs; Female; Heart Ventricles; Hypoxia; Male; NAD; Nitrogl | 1974 |
[Nitroglycerin and 4-(2'-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester tested on rabbit heart under hypoxic respiration].
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Dicarboxylic Acids; Glycogen; Heart; Hypoxia; Myoca | 1972 |
[Physiology of the coronary circulation as a basis for evaluating coronary dilators].
Topics: Animals; Blood Pressure; Carbon Dioxide; Coronary Circulation; Coronary Vessels; Disease Models, Ani | 1972 |
Potentiation of the contractile effects of norepinephrine by hypoxia.
Topics: Animals; Aorta; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Coronary Circulation; Dogs; Ele | 1972 |
Aphotographic method for measuring the mean retinal circulation time using fluorescein.
Topics: Blood Circulation Time; Carbon Dioxide; Densitometry; Fluoresceins; Fundus Oculi; Humans; Hypoxia; I | 1965 |