Page last updated: 2024-11-01

nitroglycerin and Hypothermia

nitroglycerin has been researched along with Hypothermia in 7 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.

Research Excerpts

ExcerptRelevanceReference
"Nicorandil-induced vasodilation of cerebral pial arterioles was not affected by mild hypothermia."7.71Effect of mild hypothermia on nicorandil-induced vasodilation of pial arterioles in cats. ( Furuya, H; Inoue, S; Kawaguchi, M; Kitaguchi, K; Kurehara, K; Sakamoto, T, 2001)
"Nicorandil-induced vasodilation of cerebral pial arterioles was not affected by mild hypothermia."3.71Effect of mild hypothermia on nicorandil-induced vasodilation of pial arterioles in cats. ( Furuya, H; Inoue, S; Kawaguchi, M; Kitaguchi, K; Kurehara, K; Sakamoto, T, 2001)
"Nitroglycerin treatment had no effect on either beating rate recovery or release of CPK and LDH from myocytes."1.29In vitro protective effects of nicorandil on hypothermic injury to immature cardiac myocytes: comparison with nitroglycerin. ( Fukasawa, M; Fukui, K; Hirooka, S; Kohi, M; Orita, H; Washio, M, 1994)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goenaga Díaz, EJ1
Carter, JE1
Templeton, TW1
Watson, AJ1
Gao, L1
Sun, L1
Tsun, J1
Jabbour, A1
Ru Qiu, M1
Jansz, PC1
Hicks, M1
Macdonald, PS1
MacLeod, DB1
Cortinez, LI1
Keifer, JC1
Cameron, D1
Wright, DR1
White, WD1
Moretti, EW1
Radulescu, LR1
Somma, J1
Orita, H1
Fukasawa, M1
Hirooka, S1
Fukui, K1
Kohi, M1
Washio, M1
Lapatto, O1
Kivistö, KT1
Salorinne, Y1
Morioka, N1
Ozaki, M1
Matsukawa, T1
Suzuki, H1
Inoue, S1
Kawaguchi, M1
Kurehara, K1
Sakamoto, T1
Kitaguchi, K1
Furuya, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Placebo- Controlled,Randomized,Double Blind Trial of Erythropoietin Effect on Ischemic_ Reperfusion Injury in Coronary Artery Bypass Graft Surgery[NCT02984111]97 participants (Actual)Interventional2016-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for nitroglycerin and Hypothermia

ArticleYear
The effects of glyceryl trinitrate and nicotinic acid ointments during cold exposure.
    Pharmacology & toxicology, 1997, Volume: 81, Issue:5

    Topics: Administration, Topical; Adult; Blood Pressure; Hand; Heart Rate; Humans; Hypothermia; Male; Niacin;

1997
[Transdermal nitroglycerin before induction of anesthesia prevents redistribution hypothermia in patients under general anesthesia].
    Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:12

    Topics: Administration, Cutaneous; Adult; Aged; Anesthesia, General; Female; Humans; Hypothermia; Intraopera

1998

Other Studies

5 other studies available for nitroglycerin and Hypothermia

ArticleYear
Nitroglycerin: An unusual solution to intraoperative hypothermia in a 4-year-old burn patient.
    Paediatric anaesthesia, 2018, Volume: 28, Issue:1

    Topics: Burns; Child, Preschool; Humans; Hypothermia; Infusions, Intravenous; Intraoperative Complications;

2018
Enhanced preservation of the rat heart after prolonged hypothermic ischemia with erythropoietin-supplemented Celsior solution.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2013, Volume: 32, Issue:6

    Topics: Animals; Cardioplegic Solutions; Cold Ischemia; Disaccharides; Dose-Response Relationship, Drug; Dru

2013
The desaturation response time of finger pulse oximeters during mild hypothermia.
    Anaesthesia, 2005, Volume: 60, Issue:1

    Topics: Adult; Anthropometry; Fingers; Humans; Hypothermia; Hypoxia; Male; Monitoring, Physiologic; Nitrogly

2005
In vitro protective effects of nicorandil on hypothermic injury to immature cardiac myocytes: comparison with nitroglycerin.
    Cardiovascular drugs and therapy, 1994, Volume: 8, Issue:1

    Topics: Animals; Cell Survival; Cells, Cultured; Creatine Kinase; Heart; Hypothermia; L-Lactate Dehydrogenas

1994
Effect of mild hypothermia on nicorandil-induced vasodilation of pial arterioles in cats.
    Critical care medicine, 2001, Volume: 29, Issue:11

    Topics: Administration, Topical; Animals; Cats; Cerebral Arteries; Cromakalim; Dose-Response Relationship, D

2001