nitroglycerin has been researched along with Hypotension, Postural in 28 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The orthostatic changes in heart rate (HR) and blood pressure (BP) were recorded in ten patients with stable angina pectoris before and after simultaneous sublingual nitroglycerin administration." | 9.05 | Orthostatic response before and after nitroglycerin in metoprolol- and verapamil-treated angina pectoris. ( Hyldstrup, L; Mogensen, NB; Nielsen, PE, 1983) |
| "Increments in heart rate during the TNG test (sublingual nitroglycerin with assumption of upright posture), passive head-up tilt, and postrecumbency standing were compared to the effects of intravenous isoproterenol in 15 mild hypertensives during administration of placebo and two dosage levels of propranolol." | 6.64 | Heart rate responses during treatment of hypertension with propranolol. The clinical usefulness of the nitroglycerin test. ( Hansson, L; Zweifler, AJ, 1976) |
| "The orthostatic changes in heart rate (HR) and blood pressure (BP) were recorded in ten patients with stable angina pectoris before and after simultaneous sublingual nitroglycerin administration." | 5.05 | Orthostatic response before and after nitroglycerin in metoprolol- and verapamil-treated angina pectoris. ( Hyldstrup, L; Mogensen, NB; Nielsen, PE, 1983) |
| "Ruboxistaurin is a selective protein kinase C beta inhibitor undergoing clinical investigation for treatment of diabetic microvascular complications." | 2.73 | Inhibition of PKC beta by ruboxistaurin does not enhance the acute blood pressure response to nitroglycerin. ( Benson, C; Seger, M; Voelker, J, 2007) |
| "Internal anal sphincterotomy for treating chronic anal fissure can irreversibly damage anal continence." | 2.69 | Glyceryl trinitrate for chronic anal fissure--healing or headache? Results of a multicenter, randomized, placebo-controled, double-blind trial. ( Altomare, DF; Arcanà, F; Bottini, C; Lovreglio, R; Milito, G; Nardelli, N; Pescatori, M; Pulvirenti-D'Urso, A; Rinaldi, M; Scardigno, D; Spinelli, F, 2000) |
| "In a double-blind, randomized, placebo cross-controlled trial the effectiveness and the adverse effects of two types of buccal tablets containing 5 mg nitroglycerin: Polnitrin produced by Warsaw Pharmaceutical Works POLFA and its analogue of foreign origin, were assessed." | 2.67 | [Evaluation of clinical effectiveness and adverse effects of Polnitrin]. ( Kośmicki, M; Sadowski, Z, 1992) |
| "When diltiazem was added to placebo compared to the control test, there was a 4% increase in oxygen consumption and -9% and -4% reduction in systemic resistance and systemic pressure, respectively." | 2.66 | Excessive reduction in peripheral resistance during exercise and risk of orthostatic symptoms with sustained-release nitroglycerin and diltiazem treatment of angina. ( Bruce, RA; Day, B; Hossack, KF; Kannagi, T; Kusumi, F, 1985) |
| "Increments in heart rate during the TNG test (sublingual nitroglycerin with assumption of upright posture), passive head-up tilt, and postrecumbency standing were compared to the effects of intravenous isoproterenol in 15 mild hypertensives during administration of placebo and two dosage levels of propranolol." | 2.64 | Heart rate responses during treatment of hypertension with propranolol. The clinical usefulness of the nitroglycerin test. ( Hansson, L; Zweifler, AJ, 1976) |
| "Thirteen patients had orthostatic hypotension (OH)." | 1.48 | Monitoring of cerebral oximetry during head-up tilt test in adults with history of syncope and orthostatic intolerance. ( Bachus, E; Fedorowski, A; Hamrefors, V; Holm, H; Magnusson, M; Melander, O; Sutton, R, 2018) |
| "After the procedure both symptoms and orthostatic hypotension disappeared." | 1.35 | Persistent atrial fibrillation associated with syncope due to orthostatic hypotension: a case report. ( Baratella, MC; D'este, D; Reato, S, 2009) |
| "The relative importance of the effect of absorption and first-pass extraction in bioavailability and clinical effectiveness of oraldihydroergotamine (DHE) was examined in six subjects with orthostatic hypotension." | 1.26 | Low oral bioavailability of dihydroergotamine and first-pass extraction in patients with orthostatic hypotension. ( Bobik, A; Esler, M; Jennings, G; McLean, A; Skews, H, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (39.29) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 8 (28.57) | 29.6817 |
| 2010's | 3 (10.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bachus, E | 1 |
| Holm, H | 1 |
| Hamrefors, V | 1 |
| Melander, O | 1 |
| Sutton, R | 1 |
| Magnusson, M | 1 |
| Fedorowski, A | 1 |
| Verheyden, B | 1 |
| Liu, J | 1 |
| van Dijk, N | 1 |
| Westerhof, BE | 1 |
| Reybrouck, T | 1 |
| Aubert, AE | 1 |
| Wieling, W | 1 |
| Reato, S | 1 |
| Baratella, MC | 1 |
| D'este, D | 1 |
| Rahman, F | 1 |
| Pechnik, S | 1 |
| Gross, D | 1 |
| Sewell, L | 1 |
| Goldstein, DS | 1 |
| Mørup, P | 1 |
| Levinsen, TH | 1 |
| Hovind, P | 1 |
| RONNOV-JESSEN, V | 1 |
| BIRCHFIELD, RI | 1 |
| DATLOW, DW | 1 |
| MASSUMI, RA | 1 |
| Shibao, C | 1 |
| Gamboa, A | 1 |
| Abraham, R | 1 |
| Raj, SR | 1 |
| Diedrich, A | 1 |
| Black, B | 1 |
| Robertson, D | 1 |
| Biaggioni, I | 1 |
| Benson, C | 1 |
| Seger, M | 1 |
| Voelker, J | 1 |
| Chernov, VI | 1 |
| Minin, SM | 1 |
| Makarova, EV | 1 |
| Krivoshchekov, EV | 1 |
| Lishmanov, IuB | 1 |
| Hyldstrup, L | 1 |
| Mogensen, NB | 1 |
| Nielsen, PE | 1 |
| Bobik, A | 1 |
| Jennings, G | 1 |
| Skews, H | 1 |
| Esler, M | 1 |
| McLean, A | 1 |
| Derchi, G | 1 |
| Dupuis, J | 1 |
| de Champlain, J | 1 |
| Rouleau, JL | 1 |
| Coperchini, ML | 1 |
| Kreeger, LC | 1 |
| Oldenburg, O | 1 |
| Sack, S | 1 |
| Erbel, R | 1 |
| Philipp, T | 1 |
| Kribben, A | 1 |
| Altomare, DF | 1 |
| Rinaldi, M | 1 |
| Milito, G | 1 |
| Arcanà, F | 1 |
| Spinelli, F | 1 |
| Nardelli, N | 1 |
| Scardigno, D | 1 |
| Pulvirenti-D'Urso, A | 1 |
| Bottini, C | 1 |
| Pescatori, M | 1 |
| Lovreglio, R | 1 |
| Schwinger, RH | 1 |
| Bonnin, P | 1 |
| Ben Driss, A | 1 |
| Benessiano, J | 1 |
| Maillet, A | 1 |
| Pavy le Traon, A | 1 |
| Levy, BI | 1 |
| Vogel, HC | 1 |
| Teichmann, W | 1 |
| Gerono, E | 1 |
| Seliger, G | 1 |
| Zweifler, AJ | 1 |
| Hansson, L | 1 |
| Kośmicki, M | 1 |
| Sadowski, Z | 1 |
| Tonkin, A | 1 |
| Wing, L | 1 |
| Jonsson, PV | 1 |
| Lipsitz, LA | 1 |
| Kelley, M | 1 |
| Koestner, J | 1 |
| Tatár, P | 1 |
| Bulas, J | 1 |
| Kvetnanský, R | 1 |
| Strec, V | 1 |
| Bruce, RA | 1 |
| Hossack, KF | 1 |
| Kusumi, F | 1 |
| Day, B | 1 |
| Kannagi, T | 1 |
| Tomasi, A | 1 |
| Baratta, PF | 1 |
| Nager, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Pathophysiology and Treatment of Supine Hypertension in Patients With Autonomic Failure[NCT00223717] | Phase 1 | 152 participants (Actual) | Interventional | 2001-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nitroglycerin and Hypotension, Postural
| Article | Year |
|---|---|
[Therapy of orthostatic hypotension].
Topics: Adrenergic beta-Antagonists; Cyclooxygenase Inhibitors; Deamino Arginine Vasopressin; Dihydroergotam | 1999 |
11 trials available for nitroglycerin and Hypotension, Postural
| Article | Year |
|---|---|
Clonidine for the treatment of supine hypertension and pressure natriuresis in autonomic failure.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Autonomic Nervous System; Autonomic Nervous System | 2006 |
Inhibition of PKC beta by ruboxistaurin does not enhance the acute blood pressure response to nitroglycerin.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Angina Pectoris; Blood Pressure; Chronic Di | 2007 |
Orthostatic response before and after nitroglycerin in metoprolol- and verapamil-treated angina pectoris.
Topics: Aged; Angina Pectoris; Blood Pressure; Heart Rate; Humans; Hypotension, Orthostatic; Metoprolol; Mid | 1983 |
Glyceryl trinitrate for chronic anal fissure--healing or headache? Results of a multicenter, randomized, placebo-controled, double-blind trial.
Topics: Adult; Anal Canal; Blood Flow Velocity; Chronic Disease; Double-Blind Method; Female; Fissure in Ano | 2000 |
Enhanced flow-dependent vasodilatation after bed rest, a possible mechanism for orthostatic intolerance in humans.
Topics: Adult; Bed Rest; Blood Flow Velocity; Blood Pressure; Brachial Artery; Endothelium, Vascular; Head-D | 2001 |
[Effect of vasoactive and coronary drugs on orthostasis in patients with constant-frequency cardiac pacemakers].
Topics: Aminophylline; Dihydroergotoxine; Humans; Hypotension, Orthostatic; Methods; Nitroglycerin; Pacemake | 1977 |
Heart rate responses during treatment of hypertension with propranolol. The clinical usefulness of the nitroglycerin test.
Topics: Adult; Aged; Clinical Trials as Topic; Heart Rate; Humans; Hypertension; Hypotension, Orthostatic; M | 1976 |
[Evaluation of clinical effectiveness and adverse effects of Polnitrin].
Topics: Administration, Buccal; Administration, Sublingual; Adult; Biological Availability; Coronary Disease | 1992 |
Aging and susceptibility to drug-induced orthostatic hypotension.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Analysis of Variance; Bendroflumethiazi | 1992 |
Venous plasma adrenaline response to orthostatic syncope during tilting in healthy men.
Topics: Adolescent; Adult; Epinephrine; Humans; Hypotension, Orthostatic; Male; Nitroglycerin; Norepinephrin | 1986 |
Excessive reduction in peripheral resistance during exercise and risk of orthostatic symptoms with sustained-release nitroglycerin and diltiazem treatment of angina.
Topics: Aged; Angina Pectoris; Benzazepines; Delayed-Action Preparations; Diltiazem; Drug Therapy, Combinati | 1985 |
16 other studies available for nitroglycerin and Hypotension, Postural
| Article | Year |
|---|---|
Monitoring of cerebral oximetry during head-up tilt test in adults with history of syncope and orthostatic intolerance.
Topics: Adult; Aged; Arterial Pressure; Cerebrovascular Circulation; Female; Frontal Lobe; Humans; Hypotensi | 2018 |
Steep fall in cardiac output is main determinant of hypotension during drug-free and nitroglycerine-induced orthostatic vasovagal syncope.
Topics: Adult; Blood Pressure; Body Mass Index; Electrocardiography; Female; Follow-Up Studies; Heart Ventri | 2008 |
Persistent atrial fibrillation associated with syncope due to orthostatic hypotension: a case report.
Topics: Adult; Atrial Fibrillation; Bradycardia; Electric Countershock; Electrocardiography; Humans; Hypoten | 2009 |
Low frequency power of heart rate variability reflects baroreflex function, not cardiac sympathetic innervation.
Topics: Baroreflex; Case-Control Studies; Electrophysiologic Techniques, Cardiac; Heart; Heart Rate; Humans; | 2011 |
[Glyceryl nitrates may cause hypertension].
Topics: Aged; Aged, 80 and over; Female; Humans; Hypertension; Hypotension, Orthostatic; Nitroglycerin; Tilt | 2011 |
CEREBRAL COMPLICATIONS IN NITROGLYCERINE TREATMENT OF ANGINA PECTORIS.
Topics: Angina Pectoris; Brain Ischemia; Cerebral Infarction; Humans; Hypotension; Hypotension, Orthostatic; | 1963 |
POSTURAL HYPOTENSION IN WERNICKE'S DISEASE. A MANIFESTATION OF AUTONOMIC NERVOUS SYSTEM INVOLVEMENT.
Topics: Autonomic Nervous System; Autonomic Nervous System Diseases; Blood Pressure; Blood Transfusion; Bloo | 1964 |
THE POTENTIAL CEREBRAL AND CARDIOVASCULAR DANGERS OF NITROGLYCERIN.
Topics: Brain Ischemia; Cerebral Infarction; Drug Therapy; Geriatrics; Hypotension; Hypotension, Orthostatic | 1965 |
[Scintigaraphic assessment of viability of the ischemic myocardium while carrying out nitroglycerine-mediated and orthostatic tests].
Topics: Adult; Female; Humans; Hypotension, Orthostatic; Male; Middle Aged; Myocardial Ischemia; Nitroglycer | 2006 |
Low oral bioavailability of dihydroergotamine and first-pass extraction in patients with orthostatic hypotension.
Topics: Absorption; Administration, Oral; Aged; Biological Availability; Blood Pressure; Dihydroergotamine; | 1981 |
Paradoxical decrease in circulating neuropeptide Y-like immunoreactivity during mild orthostatic stress in subjects with and without congestive heart failure.
Topics: Adult; Aged; Arousal; Catecholamines; Female; Heart Failure; Hemodynamics; Humans; Hypotension, Orth | 1993 |
Postural hypotension from topical glyceryl trinitrate ointment for anal pain.
Topics: Administration, Rectal; Adult; Anal Canal; Humans; Hypotension, Orthostatic; Male; Nitroglycerin; Oi | 1997 |
[Role of nitrates in the treatment of ischemia].
Topics: Angina Pectoris; Coronary Disease; Emergencies; Humans; Hypotension, Orthostatic; Isosorbide Dinitra | 2000 |
Hypotensive responses to common daily activities in institutionalized elderly. A potential risk for recurrent falls.
Topics: Accidental Falls; Accidents; Activities of Daily Living; Adult; Aged; Aged, 80 and over; Eating; Fem | 1990 |
[Idiopathic orthostatic hypotension].
Topics: Angiotensin II; Electroencephalography; Electromyography; Humans; Hypotension, Orthostatic; Ischemic | 1968 |
[Conservative therapy of angina pectoris].
Topics: Acute Disease; Amyl Nitrite; Angina Pectoris; Anticoagulants; Coronary Disease; Digitalis Glycosides | 1970 |