Page last updated: 2024-11-01

nitroglycerin and Hypertension, Portal

nitroglycerin has been researched along with Hypertension, Portal in 39 studies

Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.

Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.

Research Excerpts

ExcerptRelevanceReference
" The wedged hepatic venous pressure decreased after dosing by 7."2.68Portal and systemic hemodynamic responses to a very low dose of nitroglycerin in cirrhotic patients with portal hypertension. ( Aramaki, T; Katsuta, Y; Kurokawa, H; Sekiyama, T, 1995)
" The aim of this study was to examine the systemic and splanchnic hemodynamic responses to terlipressin administered alone or combined with nitroglycerin in patients with cirrhosis."2.67[Hemodynamic effects of the administration of terlipressin alone or combined with nitroglycerin in patients with cirrhosis]. ( Gaudin, C; Hadengue, A; Kleber, G; Lebrec, D; Moreau, R; Sogni, P; Soubrane, O, 1992)
"Terlipressin has longer effects and is more effective and safer than vasopressin alone or in combination with nitroglycerin."2.41The sixth Carlos E. Rubio Memorial Lecture. Prevention and treatment of variceal hemorrhage. ( Bosch, J, 2000)
"In conclusion, chronic administration of organic nitrates, allowing for a nitrate-free interval each day, to cirrhotic patients reduces portal pressure with a variable, dose-dependent effect on azygos blood flow."2.39Organic nitrates in portal hypertension. ( Hayes, PC; Jones, AL, 1994)
"The pharmacologic treatment of portal hypertension should be able to stop as well as to prevent variceal hemorrhage."2.38Pharmacologic treatment of portal hypertension. ( Groszmann, RJ; Rodríguez-Pérez, F, 1992)
" Thus, CVP can be used to guide NG dosage and fluid administration at horizontal position."1.40Nitroglycerine and patient position effect on central, hepatic and portal venous pressures during liver surgery. ( Houltz, E; Lundin, S; Rizell, M; Sand, L; Stenqvist, O; Wiklund, J, 2014)
"In 40 patients with esophageal varices, esophageal variceal pressure was assessed endoscopically using a pneumatic pressure sensor."1.29Clinical significance of esophageal variceal pressure in patients with esophageal varices. ( Bandoh, T; Kitano, S; Kobayashi, M; Mitarai, Y; Yoshida, T, 1994)
" The bioavailability of intraportal and intrajejunal nitroglycerin is influenced by the extent of portal systemic collaterals."1.27Portal-systemic shunting and the hemodynamic effects of nitroglycerin in the rat. ( Blei, AT; Gottstein, J; O'Reilly, DJ, 1984)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19908 (20.51)18.7374
1990's24 (61.54)18.2507
2000's3 (7.69)29.6817
2010's3 (7.69)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Kawaji, T2
Toyama, H2
Yoshida, N2
Moteki, S2
Sasaki, A2
Sasaki, K2
Fujio, A2
Tokodai, K2
Miyagi, S2
Yamauchi, M2
Sand, L1
Lundin, S1
Rizell, M1
Wiklund, J1
Stenqvist, O1
Houltz, E1
Sharma, M1
Babu, CS1
Dhiman, RK1
Chawla, Y1
Vujanac, A1
Jakovljevic, V1
Djordjevic, D1
Zivkovic, V1
Stojkovic, M1
Celikovic, D1
Andjelkovic, N1
Skevin, AJ1
Djuric, D1
Brensing, KA1
Hörsch, M1
Textor, J1
Schiedermaier, P1
Raab, P1
Schepke, M1
Strunk, H1
Schild, H1
Sauerbruch, T1
Blei, AT2
O'Reilly, DJ1
Gottstein, J1
Karatapanis, S1
McCormick, PA1
Kakad, S1
Chin, JK1
Islam, M1
Jeremy, J1
Harry, D1
McIntyre, N1
Burroughs, AK1
Jacobs, M1
Bosch, J3
Bruix, J1
Mas, A1
Navasa, M2
Rodés, J2
Kurokawa, H1
Sekiyama, T1
Katsuta, Y1
Aramaki, T1
Sarin, SK2
Saraya, A2
Bandoh, T1
Mitarai, Y1
Kitano, S1
Yoshida, T1
Kobayashi, M1
Noguchi, H1
Toyonaga, A3
Tanikawa, K3
Jones, AL1
Hayes, PC2
Polio, J1
Sieber, CC1
Lerner, E1
Groszmann, RJ2
Imai, F1
Sugano, S1
Suzuki, T1
Nishio, M1
Makino, H1
Okajima, T1
Renner, EL1
Rusyn, VI1
Peresta, IuIu1
Rammal', F1
Chavarha, M1
Eramishantsev, AK1
Shertsinger, AG1
Kitsenko, EA1
Bour, AV1
Bokhian, TS1
Musin, RA1
Van de Casteele, M1
Hösli, M1
Sägesser, H1
Reichen, J1
Gaenzer, H1
Sturm, W1
Neumayr, G1
Vogel, W1
Patsch, J1
Matloff, DS1
Rodríguez-Pérez, F1
Moreau, R2
Soubrane, O1
Hadengue, A1
Sogni, P1
Gaudin, C1
Kleber, G1
Lebrec, D2
Iwao, T2
Ikegami, M1
Sumino, M2
Oho, K1
Sakaki, M1
Nishizono, M1
Sweeting, J1
Takagi, K1
Ohkubo, K1
Inoue, R1
Rector, WG2
Hossack, KF2
Ready, JB1
García-Pagán, JC1
Feu, F1
Bru, C1
Ruiz del Arbol, L1
Terada, M1
Notsumata, K2
Unoura, M1
Kobayashi, K1
Hattori, N1
Maier, KP1
Westaby, D1
Gimson, A1
Williams, R1
Ganger, D1
Fung, HL1
Groszmann, R1
Sukigara, M1
Shimoji, K1
Ohata, M1
Matsumoto, T1
Komazaki, T1
Matsumura, M1
Itoh, S1
Omoto, R1

Reviews

10 reviews available for nitroglycerin and Hypertension, Portal

ArticleYear
Rolling review: the treatment of major complications of cirrhosis.
    Alimentary pharmacology & therapeutics, 1994, Volume: 8, Issue:6

    Topics: Adrenergic beta-Antagonists; Ascites; Carcinoma, Hepatocellular; Catheterization; Diuretics; Hemorrh

1994
Organic nitrates in portal hypertension.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:1

    Topics: Animals; Collateral Circulation; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans

1994
[Drug therapy for the treatment of portal hypertension].
    Nihon Geka Gakkai zasshi, 1996, Volume: 97, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Combined Modality Therapy; Diuretics; Female; Humans; Hype

1996
[Esophageal varices].
    Therapeutische Umschau. Revue therapeutique, 1997, Volume: 54, Issue:11

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Combined Modality Therapy; Drug Therapy, Combi

1997
The sixth Carlos E. Rubio Memorial Lecture. Prevention and treatment of variceal hemorrhage.
    Puerto Rico health sciences journal, 2000, Volume: 19, Issue:1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination

2000
Treatment of acute variceal bleeding.
    Gastroenterology clinics of North America, 1992, Volume: 21, Issue:1

    Topics: Acute Disease; Balloon Occlusion; Catheterization; Drug Administration Schedule; Emergencies; Endosc

1992
Pharmacologic treatment of portal hypertension.
    Gastroenterology clinics of North America, 1992, Volume: 21, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Clonidine; Gastrointestinal Hemorrha

1992
Nitrovasodilators and portal hypertension.
    Journal of hepatology, 1990, Volume: 10, Issue:3

    Topics: Humans; Hypertension, Portal; Isosorbide Dinitrate; Nitroglycerin; Vasodilator Agents

1990
[Drug treatment of bleeding esophageal varices. Acute therapy and prevention of recurrence].
    Deutsche medizinische Wochenschrift (1946), 1986, Feb-21, Volume: 111, Issue:8

    Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Drug Therapy, Combination; Esophageal and Gastr

1986
Organic nitrates in portal hypertension.
    European heart journal, 1988, Volume: 9 Suppl A

    Topics: Animals; Humans; Hypertension, Portal; Isosorbide Dinitrate; Nitroglycerin; Splanchnic Circulation

1988

Trials

9 trials available for nitroglycerin and Hypertension, Portal

ArticleYear
Hemodynamic effects of propranolol and nitrates in cirrhotics with transjugular intrahepatic portosystemic stent-shunt.
    Scandinavian journal of gastroenterology, 2002, Volume: 37, Issue:9

    Topics: Blood Pressure; Drug Combinations; Female; Heart Rate; Hemodynamics; Humans; Hypertension, Portal; L

2002
Portal and systemic hemodynamic responses to a very low dose of nitroglycerin in cirrhotic patients with portal hypertension.
    Nihon Ika Daigaku zasshi, 1995, Volume: 62, Issue:1

    Topics: Female; Hemodynamics; Humans; Hypertension, Portal; Liver Circulation; Liver Cirrhosis; Male; Middle

1995
Effects of intravenous nitroglycerin and nitroglycerin and metoclopramide on intravariceal pressure: a double blind, randomized study.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:1

    Topics: Adolescent; Adult; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Esophageal and Ga

1995
Effects of intravenous nitroglycerin and metoclopramide on intravariceal pressure: a double-blind, randomized study.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:11

    Topics: Adult; Blood Pressure; Double-Blind Method; Esophageal and Gastric Varices; Female; Humans; Hyperten

1993
Chronic splanchnic hemodynamic effects of low-dose transdermal nitroglycerin versus low-dose transdermal nitroglycerin plus spironolactone in patients with cirrhosis.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:3

    Topics: Administration, Cutaneous; Aged; Dose-Response Relationship, Drug; Drug Therapy, Combination; Esopha

1997
[Hemodynamic effects of the administration of terlipressin alone or combined with nitroglycerin in patients with cirrhosis].
    Gastroenterologie clinique et biologique, 1992, Volume: 16, Issue:8-9

    Topics: Blood Pressure; Cardiac Output; Catecholamines; Drug Therapy, Combination; Female; Hemodynamics; Hum

1992
Effect of intraportal nitroglycerin on portosystemic hemodynamics in patients with cirrhosis: comparison with i.v. route.
    Journal of clinical gastroenterology, 1991, Volume: 13, Issue:4

    Topics: Administration, Oral; Administration, Sublingual; Blood Pressure; Female; Hemodynamics; Humans; Hype

1991
Long-term haemodynamic effects of isosorbide 5-mononitrate in patients with cirrhosis and portal hypertension.
    Journal of hepatology, 1990, Volume: 11, Issue:2

    Topics: Administration, Oral; Aged; Blood Pressure; Double-Blind Method; Female; Hemodynamics; Humans; Hyper

1990
Haemodynamic response to intravenous vasopressin and nitroglycerin in portal hypertension.
    Gut, 1988, Volume: 29, Issue:3

    Topics: Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hypertension,

1988

Other Studies

20 other studies available for nitroglycerin and Hypertension, Portal

ArticleYear
Postreperfusion Syndrome Presenting as Posttransplant Portal Hypertension due to Prolonged Elevation of Pulmonary Vascular Resistance and the Role of Nitroglycerin in Diagnosis and Treatment: A Case Report of Budd-Chiari Syndrome.
    The Tohoku journal of experimental medicine, 2023, Jan-21, Volume: 259, Issue:2

    Topics: Budd-Chiari Syndrome; Female; Hemodynamics; Humans; Hypertension, Portal; Middle Aged; Nitroglycerin

2023
Postreperfusion Syndrome Presenting as Posttransplant Portal Hypertension due to Prolonged Elevation of Pulmonary Vascular Resistance and the Role of Nitroglycerin in Diagnosis and Treatment: A Case Report of Budd-Chiari Syndrome.
    The Tohoku journal of experimental medicine, 2023, Jan-21, Volume: 259, Issue:2

    Topics: Budd-Chiari Syndrome; Female; Hemodynamics; Humans; Hypertension, Portal; Middle Aged; Nitroglycerin

2023
Postreperfusion Syndrome Presenting as Posttransplant Portal Hypertension due to Prolonged Elevation of Pulmonary Vascular Resistance and the Role of Nitroglycerin in Diagnosis and Treatment: A Case Report of Budd-Chiari Syndrome.
    The Tohoku journal of experimental medicine, 2023, Jan-21, Volume: 259, Issue:2

    Topics: Budd-Chiari Syndrome; Female; Hemodynamics; Humans; Hypertension, Portal; Middle Aged; Nitroglycerin

2023
Postreperfusion Syndrome Presenting as Posttransplant Portal Hypertension due to Prolonged Elevation of Pulmonary Vascular Resistance and the Role of Nitroglycerin in Diagnosis and Treatment: A Case Report of Budd-Chiari Syndrome.
    The Tohoku journal of experimental medicine, 2023, Jan-21, Volume: 259, Issue:2

    Topics: Budd-Chiari Syndrome; Female; Hemodynamics; Humans; Hypertension, Portal; Middle Aged; Nitroglycerin

2023
Nitroglycerine and patient position effect on central, hepatic and portal venous pressures during liver surgery.
    Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:8

    Topics: Aged; Antihypertensive Agents; Blood Loss, Surgical; Blood Pressure; Carcinoma; Cardiac Output; Fema

2014
Induced hypotension in the management of acute hemobilia during therapeutic ERCP in a patient with portal biliopathy (with videos).
    Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6

    Topics: Adult; Cholangiography; Cholangiopancreatography, Endoscopic Retrograde; Common Bile Duct; Endosonog

2010
Nitroglycerine effects on portal vein mechanics and oxidative stress in portal hypertension.
    World journal of gastroenterology, 2012, Jan-28, Volume: 18, Issue:4

    Topics: Adult; Female; Hemodynamics; Humans; Hydrogen Peroxide; Hypertension, Portal; Lipid Peroxidation; Ma

2012
Portal-systemic shunting and the hemodynamic effects of nitroglycerin in the rat.
    Gastroenterology, 1984, Volume: 86, Issue:6

    Topics: Animals; Blood Pressure; Cerium Radioisotopes; Collateral Circulation; Hypertension, Portal; Male; N

1984
Alteration in vascular reactivity in isolated aortic rings from portal vein-constricted rats.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:6

    Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Constriction; Hypertension, Por

1994
Clinical significance of esophageal variceal pressure in patients with esophageal varices.
    Journal of hepatology, 1994, Volume: 21, Issue:3

    Topics: Aged; Blood Pressure; Blood Pressure Determination; Esophageal and Gastric Varices; Esophagoscopy; E

1994
Influence of nitroglycerin on portal pressure and gastric mucosal hemodynamics in patients with cirrhosis.
    Journal of gastroenterology, 1994, Volume: 29, Issue:2

    Topics: Adult; Aged; Female; Gastric Mucosa; Hemodynamics; Humans; Hypertension, Portal; Liver Cirrhosis; Ma

1994
Cardiovascular hyporesponsiveness to norepinephrine, propranolol and nitroglycerin in portal-hypertensive and aged rats.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:1

    Topics: Aging; Animals; Blood Pressure; Cardiovascular System; Dose-Response Relationship, Drug; Heart Rate;

1993
[The use of nitroglycerin in integral treatment of hemorrhage with portal hypertension].
    Klinichna khirurhiia, 1997, Issue:11-12

    Topics: Acute Disease; Adult; Esophagus; Female; Hemorrhage; Humans; Hypertension, Portal; Male; Middle Aged

1997
[The conservative therapy of acute esophagogastric hemorrhages in portal hypertension patients].
    Klinicheskaia meditsina, 1998, Volume: 76, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Combined Modality Therapy; Drug Therapy, Combination; Endosc

1998
Intraportal administration of glyceryl trinitrate or nitroprusside exerts more systemic than intrahepatic effects in anaesthetised cirrhotic rats.
    Journal of hepatology, 1999, Volume: 31, Issue:2

    Topics: Animals; Blood Pressure; Hypertension, Portal; Infusions, Intravenous; Liver Circulation; Liver Cirr

1999
Hyperdynamic circulation in liver cirrhosis: no evidence for peripheral vasodilation detected by ultrasound of the brachial artery.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:2

    Topics: Adult; Aged; Blood Pressure; Brachial Artery; Female; Heart Rate; Humans; Hypertension, Portal; Live

2000
Portohepatic pressures, hepatic function, and blood gases in the combination of nitroglycerin and vasopressin: search for additive effects in cirrhotic portal hypertension.
    The American journal of gastroenterology, 1992, Volume: 87, Issue:6

    Topics: Aged; Catheterization, Peripheral; Child; Drug Therapy, Combination; Esophageal and Gastric Varices;

1992
Nitroglycerin in the treatment of portal hypertension.
    Gastroenterology, 1991, Volume: 101, Issue:2

    Topics: Female; Humans; Hypertension, Portal; Male; Nitroglycerin; Portal Vein; Vascular Resistance; Venous

1991
Nitroglycerin for portal hypertension. A controlled comparison of the hemodynamic effects of graded doses.
    Journal of hepatology, 1990, Volume: 10, Issue:3

    Topics: Adult; Arteries; Coronary Circulation; Dose-Response Relationship, Drug; Female; Hemodynamics; Human

1990
Vasopressin and vasopressin plus nitroglycerin for portal hypertension. Effects on systemic and splanchnic hemodynamics and coronary blood flow.
    Journal of hepatology, 1989, Volume: 8, Issue:3

    Topics: Adult; Coronary Circulation; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension, Portal;

1989
Effects of propranolol and nitroglycerin on portal pressure and the mechanism of their reducing portal pressure.
    Journal of gastroenterology and hepatology, 1989, Volume: 4 Suppl 1

    Topics: Drug Therapy, Combination; Hemodynamics; Humans; Hypertension, Portal; Liver Circulation; Nitroglyce

1989
[The effects of propranolol or nitroglycerin on azygos blood flow in patients with portal hypertension].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1986, Volume: 83, Issue:8

    Topics: Azygos Vein; Humans; Hypertension, Portal; Nitroglycerin; Propranolol; Regional Blood Flow

1986
Effects of propranolol and nitroglycerin on cephalad collateral venous flow in patients with cirrhosis: evaluation using transesophageal real-time two-dimensional Doppler echography.
    The American journal of gastroenterology, 1988, Volume: 83, Issue:11

    Topics: Aged; Aorta; Azygos Vein; Blood Flow Velocity; Collateral Circulation; Color; Female; Humans; Hypert

1988